DL-MANDELIC ACID BENZYL ESTER
Title | Journal |
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Expression of drug transporters and drug metabolizing enzymes in the bladder urothelium in man and affinity of the bladder spasmolytic trospium chloride to transporters likely involved in its pharmacokinetics. | Molecular pharmaceutics 20150105 |
Benefits and harms of pharmacologic treatment for urinary incontinence in women: a systematic review. | Annals of internal medicine 20120619 |
Once-daily trospium chloride 60 mg extended-release provides effective, long-term relief of overactive bladder syndrome symptoms. | Neurourology and urodynamics 20110901 |
Once-daily administration of trospium chloride extended release provides 24-hr coverage of nocturnal and diurnal symptoms of overactive bladder: an integrated analysis of two phase III trials. | Neurourology and urodynamics 20110401 |
Trospium chloride once-daily extended release is efficacious and tolerated in elderly subjects (aged ≥ 75 years) with overactive bladder syndrome. | BJU international 20110201 |
Oxybutynin and trospium are substrates of the human organic cation transporters. | Naunyn-Schmiedeberg's archives of pharmacology 20110201 |
Once-daily trospium chloride 60 mg extended release in subjects with overactive bladder syndrome who use multiple concomitant medications: Post hoc analysis of pooled data from two randomized, placebo-controlled trials. | Drugs & aging 20110201 |
Safety and efficacy of once-daily trospium chloride extended-release in male patients with overactive bladder. | Urology 20110101 |
New once-daily formulation for trospium in overactive bladder. | International journal of clinical practice 20101001 |
New strategies for medical management of overactive bladder in children. | Current opinion in urology 20100701 |
Determination of the quaternary ammonium compound trospium in human plasma by LC-MS/MS: application to a pharmacokinetic study. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100415 |
Effects of combined use of trospium chloride and melatonin on in vitro contractility of rat urinary bladder. | Urology 20100401 |
Editorial comment. | Urology 20100401 |
Pharmacokinetics of once-daily trospium chloride 60 mg extended release and twice-daily trospium chloride 20 mg in healthy adults. | Journal of clinical pharmacology 20100201 |
Extended-release trospium chloride improves quality of life in overactive bladder. | Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20100101 |
Dose escalation improves therapeutic outcome: post hoc analysis of data from a 12-week, multicentre, double-blind, parallel-group trial of trospium chloride in patients with urinary urge incontinence. | BMC urology 20100101 |
[Sexual dysfunction in women with overactive bladder and their correction with m-cholinolytic spasmex]. | Urologiia (Moscow, Russia : 1999) 20100101 |
Trospium chloride extended release is effective and well tolerated in women with overactive bladder syndrome. | International urogynecology journal and pelvic floor dysfunction 20091201 |
Trospium chloride once-daily extended release is effective and well tolerated for the treatment of overactive bladder syndrome: an integrated analysis of two randomised, phase III trials. | International journal of clinical practice 20091201 |
Trospium chloride and oxybutynin hydrochloride in a german study of adults with urinary urge incontinence: results of a 12-week, multicenter, randomized, double-blind, parallel-group, flexible-dose noninferiority trial. | Clinical therapeutics 20091101 |
Trospium and cognition in patients with late onset Alzheimer disease. | The journal of nutrition, health & aging 20091001 |
The role of p-glycoprotein in limiting brain penetration of the peripherally acting anticholinergic overactive bladder drug trospium chloride. | Drug metabolism and disposition: the biological fate of chemicals 20090701 |
Trospium chloride treatment of overactive bladder. | The Annals of pharmacotherapy 20090201 |
[Spasmex in the treatment of overactive bladder. Russian experience]. | Urologiia (Moscow, Russia : 1999) 20090101 |
The effects of reformulation: improved therapeutic index. | Current urology reports 20081101 |
Effective treatment of neurogenic detrusor dysfunction by combined high-dosed antimuscarinics without increased side-effects. | European urology 20080501 |
Overactive bladder disease: the urge for better therapies. | Journal of managed care pharmacy : JMCP 20080501 |
Trospium 60 mg once daily (QD) for overactive bladder syndrome: results from a placebo-controlled interventional study. | Urology 20080301 |
Role of trospium chloride in brachytherapy-related detrusor overactivity. | Urology 20080301 |
[Comparative characteristics of M-cholinolytics in combined treatment of mixed urinary incontinence in women]. | Urologiia (Moscow, Russia : 1999) 20080101 |
New drugs and dosage forms. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070915 |
Comparison of the efficacy and tolerability of solifenacin succinate with or without previous use of trospium chloride. | International urogynecology journal and pelvic floor dysfunction 20070901 |
Once daily trospium chloride is effective and well tolerated for the treatment of overactive bladder: results from a multicenter phase III trial. | The Journal of urology 20070901 |
Treatment of overactive bladder: selective use of anticholinergic agents with low drug-drug interaction potential. | Geriatrics 20070501 |
[M-cholinolytic spasmex and its role in preoperative preparation of patients with urine incontinence]. | Urologiia (Moscow, Russia : 1999) 20070101 |
[Trospium chloride (spasmex) in the treatment of lower urinary tract symptoms in patients with neurogenic hyperactive urinary bladder caused by vertebrogenic lesions]. | Urologiia (Moscow, Russia : 1999) 20070101 |
Trospium chloride in patients with neurogenic detrusor overactivity: is dose titration of benefit to the patients? | International journal of clinical pharmacology and therapeutics 20061201 |
Trospium chloride: Distinct among other anticholinergic agents available for the treatment of overactive bladder. | The Urologic clinics of North America 20061101 |
Treatment of the overactive bladder syndrome with muscarinic receptor antagonists: a matter of metabolites? | Naunyn-Schmiedeberg's archives of pharmacology 20061101 |
Predictive power of an in vitro system to assess drug interactions of an antimuscarinic medication: a comparison of in vitro and in vivo drug-drug interaction studies of trospium chloride with digoxin. | Journal of clinical pharmacology 20060701 |
Using anticholinergics to treat overactive bladder: the issue of treatment tolerability. | The American journal of medicine 20060301 |
Neurogenic bladder treatment by doubling the recommended antimuscarinic dosage. | Neurourology and urodynamics 20060101 |
[Tuberculosis of the urinary bladder: diagnosis and treatment]. | Urologiia (Moscow, Russia : 1999) 20060101 |
Trospium chloride: an anticholinergic quaternary ammonium compound for the treatment of overactive bladder. | Expert opinion on pharmacotherapy 20050701 |
Overactive bladder. | Cleveland Clinic journal of medicine 20050701 |
The overactive bladder-symptom composite score: a composite symptom score of toilet voids, urgency severity and urge urinary incontinence in patients with overactive bladder. | The Journal of urology 20050501 |
Trospium chloride for the treatment of overactive bladder with urge incontinence. | Clinical therapeutics 20050501 |
Effects on sleep of anticholinergics used for overactive bladder treatment in healthy volunteers aged > or = 50 years. | BJU international 20050201 |
Antimuscarinic agents exhibit local inhibitory effects on muscarinic receptors in bladder-afferent pathways. | Urology 20050201 |
Clinical pharmacokinetics of trospium chloride. | Clinical pharmacokinetics 20050101 |
[Neurological aspect of the hyperactive urinary bladder syndrome]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20050101 |
[Trospium chloride in the treatment of idiopathic and neurogenic detrusor overactivity]. | Urologiia (Moscow, Russia : 1999) 20050101 |
Preview of new drugs for overactive bladder and incontinence: darifenacin, solifenacin, trospium, and duloxetine. | Current urology reports 20041001 |
Elevating our therapeutic expectations in overactive bladder. | Journal of the American Academy of Nurse Practitioners 20041001 |
Trospium chloride improves overactive bladder symptoms: a multicenter phase III trial. | The Journal of urology 20040601 |
[The combined treatment of interstitial cystitis in women with spasmex]. | Urologiia (Moscow, Russia : 1999) 20040101 |
[Combined treatment of voiding disorders in women with m-cholinolytic and alpha 1-adrenoblocker]. | Urologiia (Moscow, Russia : 1999) 20040101 |
Trospium chloride in the management of overactive bladder. | Drugs 20040101 |
Trospium chloride: a quaternary amine with unique pharmacologic properties. | Current urology reports 20031201 |
Update on overactive bladder: pharmacologic approaches on the horizon. | Current urology reports 20031001 |
Controlled, double-blind, multicentre clinical trial to investigate long-term tolerability and efficacy of trospium chloride in patients with detrusor instability. | World journal of urology 20030501 |
[Urinary incontinence--treatment]. | Deutsche medizinische Wochenschrift (1946) 20030404 |
[Spasmex treatment of patients with hyperactive urinary bladder]. | Urologiia (Moscow, Russia : 1999) 20030101 |
Trospium chloride--an effective drug in the treatment of overactive bladder and detrusor hyperreflexia. | World journal of urology 20011101 |
Effects of tolterodine, trospium chloride, and oxybutynin on the central nervous system. | Journal of clinical pharmacology 20010601 |