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Tetryzoline

CAS No.:
84-22-0
Catalog Number:
AG00G28N
Molecular Formula:
C13H16N2
Molecular Weight:
200.2795
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Product Description
Catalog Number:
AG00G28N
Chemical Name:
Tetryzoline
CAS Number:
84-22-0
Molecular Formula:
C13H16N2
Molecular Weight:
200.2795
MDL Number:
MFCD00216026
IUPAC Name:
2-(1,2,3,4-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazole
InChI:
InChI=1S/C13H16N2/c1-2-6-11-10(4-1)5-3-7-12(11)13-14-8-9-15-13/h1-2,4,6,12H,3,5,7-9H2,(H,14,15)
InChI Key:
BYJAVTDNIXVSPW-UHFFFAOYSA-N
SMILES:
C1CN=C(N1)C1CCCc2c1cccc2
EC Number:
201-522-3
Properties
Complexity:
259  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
200.131g/mol
Formal Charge:
0
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
200.285g/mol
Monoisotopic Mass:
200.131g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
24.4A^2
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0
XLogP3:
1.8  
Literature
Title Journal
Use of tetrahydrozoline for chemical submission. Forensic science international 20120910
Development of prilocaine gels for enhanced local anesthetic action. Archives of pharmacal research 20120701
Drug-facilitated sexual assault using tetrahydrozoline. Journal of forensic sciences 20120501
Safety and efficacy of topical azithromycin ophthalmic solution 1.0% in the treatment of contact lens-related dry eye. Eye & contact lens 20120301
New formulations of local anaesthetics-part I. Anesthesiology research and practice 20120101
Ocular medicines in children: the regulatory situation related to clinical research. BMC pediatrics 20120101
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). PLoS computational biology 20111201
A randomized controlled trial of intralesional bevacizumab injection on primary pterygium: preliminary results. Cornea 20111101
Tetrahydrozoline (Visine®) concentrations in serum and urine during therapeutic ocular dosing: a necessary first step in determining an overdose. Clinical toxicology (Philadelphia, Pa.) 20111101
Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2. Journal of medicinal chemistry 20110714
Serum concentrations in three children with unintentional tetrahydrozoline overdose. Clinical toxicology (Philadelphia, Pa.) 20110601
Enhanced local anesthetic action of mepivacaine from the bioadhesive gels. Pakistan journal of pharmaceutical sciences 20110101
Automatic extraction of semantic relations between medical entities: a rule based approach. Journal of biomedical semantics 20110101
2-(1,2,3,4-Tetra-hydro-1-naphth-yl)imidazolium chloride monohydrate. Acta crystallographica. Section E, Structure reports online 20100901
Naloxone use in a newborn with apnea due to tetrahydrozoline intoxication. Pediatrics international : official journal of the Japan Pediatric Society 20100601
A comparative kinetic and mechanistic study between tetrahydrozoline and naphazoline toward photogenerated reactive oxygen species. Photochemistry and photobiology 20100101
Determination of tetrahydrozoline in urine and blood using gas chromatography-mass spectrometry (GC-MS). Methods in molecular biology (Clifton, N.J.) 20100101
Development of a multicommutated flow system with chemiluminometric detection for quantification of gentamicin in pharmaceuticals. Journal of automated methods & management in chemistry 20100101
Prolonged cardiovascular effects after unintentional ingestion of tetrahydrozoline. Clinical toxicology (Philadelphia, Pa.) 20080201
Patient use of Visine (tetrahydrozoline) masks Horner syndrome. The British journal of ophthalmology 20080101
Drug facilitated sexual assault using an over-the-counter ocular solution containing tetrahydrozoline (Visine). Legal medicine (Tokyo, Japan) 20070701
Comparative evaluation of antimicrobial efficacy of sodium hypochlorite, MTAD, and Tetraclean against Enterococcus faecalis biofilm. Journal of endodontics 20070701
Antagonism by imidazoline-type drugs of muscarinic and other receptors in the guinea-pig ileum. Autonomic & autacoid pharmacology 20060701
[Drug administration in newborns. Is clinical experience enough?]. Anales de pediatria (Barcelona, Spain : 2003) 20060401
Ophthalmic delivery systems based on drug-polymer-polymer ionic ternary interaction: in vitro and in vivo characterization. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20060101
[Systemic involvement in premature infants after intranasal administration of tetryzoline drops]. Anales de pediatria (Barcelona, Spain : 2003) 20051001
Effects of two eye drop products on computer users with subjective ocular discomfort. Optometry (St. Louis, Mo.) 20050101
Simple HPLC determination of benzalkonium chloride in ophthalmic formulations containing antazoline and tetrahydrozoline. PDA journal of pharmaceutical science and technology 20050101
Sinoatrial node arrest following tetrahydrozoline ingestion. The Journal of emergency medicine 20041001
[The tolerability of nasal drugs with special regard to preservatives and physico-chemical parameters]. Laryngo- rhino- otologie 20031101
Pediatric Visine (tetrahydrozoline) ingestion: case report and review of imidazoline toxicity. Veterinary and human toxicology 20030801
Transdermal penetration of vasoconstrictors--present understanding and assessment of the human epidermal flux and retention of free bases and ion-pairs. Pharmaceutical research 20030201
[Acute exposure to imidazoline derivatives in children]. Jornal de pediatria 20030101
Simultaneous determination of ofloxacin, tetrahydrozoline hydrochloride, and prednisolone acetate by high-performance liquid chromatography. Journal of chromatographic science 20020901
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. The Journal of biological chemistry 20020419
Electron microscopic analysis of the effects of chemical retraction agents on cultured rat keratinocytes. The Journal of prosthetic dentistry 20020101
Viability of fibroblasts in cell culture after treatment with different chemical retraction agents. Journal of oral rehabilitation 20020101
Gingival inflammatory response induced by chemical retraction agents in beagle dogs. The International journal of prosthodontics 20020101
Gingival tissue inflammatory response following treatment with chemical retraction agents in Beagle dogs. Pflugers Archiv : European journal of physiology 20010101
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