4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol
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Targeting C4-demethylating genes in the cholesterol pathway sensitizes cancer cells to EGF receptor inhibitors via increased EGF receptor degradation. | Cancer discovery 20130101 |
Analysis of hypoxia and hypoxia-like states through metabolite profiling. | PloS one 20110101 |
Characterization of sterol lipids in Kluyveromyces lactis strain M-16 accumulating a high amount of steryl glucoside. | Journal of oleo science 20090101 |
Preservation of genes involved in sterol metabolism in cholesterol auxotrophs: facts and hypotheses. | PloS one 20080101 |
Essential gene identification and drug target prioritization in Aspergillus fumigatus. | PLoS pathogens 20070301 |
Characterizing sterol defect suppressors uncovers a novel transcriptional signaling pathway regulating zymosterol biosynthesis. | The Journal of biological chemistry 20051028 |
The ERG28-encoded protein, Erg28p, interacts with both the sterol C-4 demethylation enzyme complex as well as the late biosynthetic protein, the C-24 sterol methyltransferase (Erg6p). | Biochimica et biophysica acta 20041108 |
Enzymological properties of sterol-C4-methyl-oxidase of yeast sterol biosynthesis. | Biochimica et biophysica acta 20030721 |
In yeast sterol biosynthesis the 3-keto reductase protein (Erg27p) is required for oxidosqualene cyclase (Erg7p) activity. | Biochimica et biophysica acta 20030704 |
PF1163A, a novel antifungal agent, inhibit ergosterol biosynthesis at C-4 sterol methyl oxidase. | The Journal of antibiotics 20021101 |
Sterol-dependent regulation of sphingolipid metabolism in Saccharomyces cerevisiae. | The Journal of biological chemistry 20020719 |
The effect of the erg26-1 mutation on the regulation of lipid metabolism in Saccharomyces cerevisiae. | The Journal of biological chemistry 20010420 |