3-IODOTHYRONAMINE-[ETHYLAMINO-1,1,2,2-2H4] HYDROCHLORIDE
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Biosynthesis of 3-iodothyronamine (T1AM) is dependent on the sodium-iodide symporter and thyroperoxidase but does not involve extrathyroidal metabolism of T4. | Endocrinology 20121101 |
Identification and quantification of 3-iodothyronamine metabolites in mouse serum using liquid chromatography-tandem mass spectrometry. | Journal of chromatography. A 20120921 |
Mitochondrial F(0) F(1) -ATP synthase is a molecular target of 3-iodothyronamine, an endogenous metabolite of thyroid hormone. | British journal of pharmacology 20120801 |
Distribution of exogenous [125I]-3-iodothyronamine in mouse in vivo: relationship with trace amine-associated receptors. | The Journal of endocrinology 20120601 |
3-Iodothyronamine: a modulator of the hypothalamus-pancreas-thyroid axes in mice. | British journal of pharmacology 20120501 |
Induction of torpor: mimicking natural metabolic suppression for biomedical applications. | Journal of cellular physiology 20120401 |
ApoB-100-containing lipoproteins are major carriers of 3-iodothyronamine in circulation. | The Journal of biological chemistry 20120113 |
Detection of 3-iodothyronamine in human patients: a preliminary study. | The Journal of clinical endocrinology and metabolism 20120101 |
Revisiting thyroid hormones in schizophrenia. | Journal of thyroid research 20120101 |
LTI models for 3-iodothyronamine time dynamics: a multiscale view. | IEEE transactions on bio-medical engineering 20111201 |
Trace amine-associated receptor 1 is a stereoselective binding site for compounds in the amphetamine class. | Bioorganic & medicinal chemistry 20111201 |
3-Iodothyronamine metabolism and functional effects in FRTL5 thyroid cells. | Journal of molecular endocrinology 20110801 |
Cardioprotective effect of 3-iodothyronamine in perfused rat heart subjected to ischemia and reperfusion. | Cardiovascular drugs and therapy 20110801 |
Effects of the thyroid hormone derivatives 3-iodothyronamine and thyronamine on rat liver oxidative capacity. | Molecular and cellular endocrinology 20110720 |
Evidence for extrathyroidal formation of 3-iodothyronamine in humans as provided by a novel monoclonal antibody-based chemiluminescent serum immunoassay. | The Journal of clinical endocrinology and metabolism 20110601 |
Endogenous 3-iodothyronamine (T1AM): more than we bargained for. | The Journal of clinical endocrinology and metabolism 20110601 |
Sustained torpidity following multi-dose administration of 3-iodothyronamine in mice. | Journal of cellular physiology 20110401 |
Thyronamines--past, present, and future. | Endocrine reviews 20110201 |
Nongenomic signaling pathways triggered by thyroid hormones and their metabolite 3-iodothyronamine on the cardiovascular system. | Journal of cellular physiology 20110101 |
The central effects of thyroid hormones on appetite. | Journal of thyroid research 20110101 |
Primary and secondary thyroid hormone transporters. | Thyroid research 20110101 |
Differential modulation of Beta-adrenergic receptor signaling by trace amine-associated receptor 1 agonists. | PloS one 20110101 |
Tissue distribution and cardiac metabolism of 3-iodothyronamine. | Endocrinology 20101001 |
An online solid-phase extraction-liquid chromatography-tandem mass spectrometry method to study the presence of thyronamines in plasma and tissue and their putative conversion from 13C6-thyroxine. | The Journal of endocrinology 20100901 |
Transport of thyroid hormones is selectively inhibited by 3-iodothyronamine. | Molecular bioSystems 20100801 |
3-Iodothyronamine (T(1)AM): a new chapter of thyroid hormone endocrinology? | Molecular bioSystems 20100801 |
Normal thermoregulatory responses to 3-iodothyronamine, trace amines and amphetamine-like psychostimulants in trace amine associated receptor 1 knockout mice. | Journal of neuroscience research 20100701 |
Cardiac effects of thyronamines. | Heart failure reviews 20100301 |
Prokineticin 2 is a hypothalamic neuropeptide that potently inhibits food intake. | Diabetes 20100201 |
Structural and functional evolution of the trace amine-associated receptors TAAR3, TAAR4 and TAAR5 in primates. | PloS one 20100101 |
Modulation of cardiac ionic homeostasis by 3-iodothyronamine. | Journal of cellular and molecular medicine 20090901 |
Central effects of thyronamines on glucose metabolism in rats. | The Journal of endocrinology 20090601 |
Identification and characterization of 3-iodothyronamine intracellular transport. | Endocrinology 20090401 |
The molecular basis of species-specific ligand activation of trace amine-associated receptor 1 (TAAR(1)). | ACS chemical biology 20090320 |
The thyroid hormone derivative 3-iodothyronamine increases food intake in rodents. | Diabetes, obesity & metabolism 20090301 |
Minireview: 3-Iodothyronamine (T1AM): a new player on the thyroid endocrine team? | Endocrinology 20090301 |
Iodothyronamines are oxidatively deaminated to iodothyroacetic acids in vivo. | Chembiochem : a European journal of chemical biology 20090126 |
Thyroid hormone analogs and metabolites: new applications for an old hormone? | Nature clinical practice. Endocrinology & metabolism 20090101 |
Validation of a liquid chromatography-tandem mass spectrometry method to enable quantification of 3-iodothyronamine from serum. | Journal of chromatography. A 20081107 |
Cardiac effects of trace amines: pharmacological characterization of trace amine-associated receptors. | European journal of pharmacology 20080610 |
Toward deciphering the code to aminergic G protein-coupled receptor drug design. | Chemistry & biology 20080401 |
3-Iodothyronamine: a novel hormone controlling the balance between glucose and lipid utilisation. | Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20080201 |
Metabolic effects of thyroid hormone derivatives. | Thyroid : official journal of the American Thyroid Association 20080201 |
Probing cell type-specific functions of Gi in vivo identifies GPCR regulators of insulin secretion. | The Journal of clinical investigation 20071203 |
Trace amine-associated receptor 1-Family archetype or iconoclast? | Pharmacology & therapeutics 20071201 |
Central nervous system regulation of mammalian hibernation: implications for metabolic suppression and ischemia tolerance. | Journal of neurochemistry 20070901 |
Novel thyroxine derivatives, thyronamine and 3-iodothyronamine, induce transient hypothermia and marked neuroprotection against stroke injury. | Stroke 20070901 |
Exploring the structure-activity relationship of the ethylamine portion of 3-iodothyronamine for rat and mouse trace amine-associated receptor 1. | Journal of medicinal chemistry 20070614 |
Cardiac effects of 3-iodothyronamine: a new aminergic system modulating cardiac function. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070501 |
Thyronamines are substrates for human liver sulfotransferases. | Endocrinology 20070401 |
Trace amine-associated receptors and their ligands. | British journal of pharmacology 20061201 |
Rapid modulation of TRH-like peptides in rat brain by thyroid hormones. | Peptides 20060601 |
Trace amine-associated receptor agonists: synthesis and evaluation of thyronamines and related analogues. | Journal of medicinal chemistry 20060209 |
3-Iodothyronamine is an endogenous and rapid-acting derivative of thyroid hormone. | Nature medicine 20040601 |