Silvestrol
Title | Journal |
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Synthetic silvestrol analogues as potent and selective protein synthesis inhibitors. | Journal of medicinal chemistry 20121025 |
Total synthesis of 2''',5'''-diepisilvestrol and its C1''' epimer: key structure activity relationships at C1''' and C2'''. | Journal of natural products 20120824 |
Synthesis of rocaglamide hydroxamates and related compounds as eukaryotic translation inhibitors: synthetic and biological studies. | Journal of medicinal chemistry 20120112 |
Resistance to the translation initiation inhibitor silvestrol is mediated by ABCB1/P-glycoprotein overexpression in acute lymphoblastic leukemia cells. | The AAPS journal 20110901 |
The relevance of higher plants in lead compound discovery programs. | Journal of natural products 20110624 |
Resorcylic acid lactones with cytotoxic and NF-κB inhibitory activities and their structure-activity relationships. | Journal of natural products 20110527 |
Isolation and characterization of minor analogues of silvestrol and other constituents from a large-scale re-collection of Aglaia foveolata. | Journal of natural products 20101129 |
Synergistic effect of inhibiting translation initiation in combination with cytotoxic agents in acute myelogenous leukemia cells. | Leukemia research 20100401 |
Inhibitors of translation initiation as cancer therapeutics. | Future medicinal chemistry 20091201 |
Synthetic analogue of rocaglaol displays a potent and selective cytotoxicity in cancer cells: involvement of apoptosis inducing factor and caspase-12. | Journal of medicinal chemistry 20090827 |
Total synthesis of the potent anticancer Aglaia metabolites (-)-silvestrol and (-)-episilvestrol and the active analogue (-)-4'-desmethoxyepisilvestrol. | Journal of the American Chemical Society 20090204 |
Antitumor activity and mechanism of action of the cyclopenta[b]benzofuran, silvestrol. | PloS one 20090101 |
Therapeutic suppression of translation initiation modulates chemosensitivity in a mouse lymphoma model. | The Journal of clinical investigation 20080701 |
Silvestrol, a potential anticancer rocaglate derivative from Aglaia foveolata, induces apoptosis in LNCaP cells through the mitochondrial/apoptosome pathway without activation of executioner caspase-3 or -7. | Anticancer research 20070101 |
Total synthesis of (-)-episilvestrol and (-)-silvestrol. | Angewandte Chemie (International ed. in English) 20070101 |
Silvestrol regulates G2/M checkpoint genes independent of p53 activity. | Anticancer research 20060101 |
Silvestrol and episilvestrol, potential anticancer rocaglate derivatives from Aglaia silvestris. | The Journal of organic chemistry 20040514 |