Nesbuvir
| Title | Journal |
|---|---|
| Hepatitis C replication inhibitors that target the viral NS4B protein. | Journal of medicinal chemistry 20140313 |
| In vitro characterization of GSK2485852, a novel hepatitis C virus polymerase inhibitor. | Antimicrobial agents and chemotherapy 20131101 |
| In vitro efficacy of approved and experimental antivirals against novel genotype 3 hepatitis C virus subgenomic replicons. | Antiviral research 20131101 |
| Restoration of the activated Rig-I pathway in hepatitis C virus (HCV) replicon cells by HCV protease, polymerase, and NS5A inhibitors in vitro at clinically relevant concentrations. | Antimicrobial agents and chemotherapy 20130901 |
| Discovery of substituted N-phenylbenzenesulphonamides as a novel class of non-nucleoside hepatitis C virus polymerase inhibitors. | Antiviral research 20120801 |
| MK-5172, a selective inhibitor of hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants. | Antimicrobial agents and chemotherapy 20120801 |
| Cellular growth kinetics distinguish a cyclophilin inhibitor from an HSP90 inhibitor as a selective inhibitor of hepatitis C virus. | PloS one 20120101 |
| The hepatitis C virus (HCV) NS4B RNA binding inhibitor clemizole is highly synergistic with HCV protease inhibitors. | The Journal of infectious diseases 20100701 |
| Mechanisms of activity and inhibition of the hepatitis C virus RNA-dependent RNA polymerase. | The Journal of biological chemistry 20100430 |
| Inhibitors of hepatitis C virus polymerase: synthesis and characterization of novel 2-oxy-6-fluoro-N-((S)-1-hydroxy-3-phenylpropan-2-yl)-benzamides. | Bioorganic & medicinal chemistry letters 20100401 |
| Slow binding inhibition and mechanism of resistance of non-nucleoside polymerase inhibitors of hepatitis C virus. | The Journal of biological chemistry 20090605 |
| Substituted imidazopyridines as potent inhibitors of HCV replication. | Journal of hepatology 20090501 |
| Severe hepatocellular injury with apoptosis induced by a hepatitis C polymerase inhibitor. | Journal of clinical gastroenterology 20090401 |
| HCV796: A selective nonstructural protein 5B polymerase inhibitor with potent anti-hepatitis C virus activity in vitro, in mice with chimeric human livers, and in humans infected with hepatitis C virus. | Hepatology (Baltimore, Md.) 20090301 |
| Molecular mechanism of hepatitis C virus replicon variants with reduced susceptibility to a benzofuran inhibitor, HCV-796. | Antimicrobial agents and chemotherapy 20080901 |
| Existence of hepatitis C virus NS5B variants naturally resistant to non-nucleoside, but not to nucleoside, polymerase inhibitors among untreated patients. | The Journal of antimicrobial chemotherapy 20080601 |
| The hepatitis C virus replicon presents a higher barrier to resistance to nucleoside analogs than to nonnucleoside polymerase or protease inhibitors. | Antimicrobial agents and chemotherapy 20080501 |