Ar 231453
Title | Journal |
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Discovery of a second generation agonist of the orphan G-protein coupled receptor GPR119 with an improved profile. | Bioorganic & medicinal chemistry letters 20120215 |
Stimulating β-cell replication and improving islet graft function by AR231453, A GPR119 agonist. | Transplantation proceedings 20111101 |
Discovery of fused bicyclic agonists of the orphan G-protein coupled receptor GPR119 with in vivo activity in rodent models of glucose control. | Bioorganic & medicinal chemistry letters 20110515 |
GPR119 regulates murine glucose homeostasis through incretin receptor-dependent and independent mechanisms. | Endocrinology 20110201 |
Discovery of the first potent and orally efficacious agonist of the orphan G-protein coupled receptor 119. | Journal of medicinal chemistry 20080911 |
A role for intestinal endocrine cell-expressed g protein-coupled receptor 119 in glycemic control by enhancing glucagon-like Peptide-1 and glucose-dependent insulinotropic Peptide release. | Endocrinology 20080501 |
A role for beta-cell-expressed G protein-coupled receptor 119 in glycemic control by enhancing glucose-dependent insulin release. | Endocrinology 20070601 |