NICOTINIC-D4 ACID
| Title | Journal |
|---|---|
| Perindopril, fosinopril and losartan inhibited the progression of diethylnitrosamine-induced hepatocellular carcinoma in mice via the inactivation of nuclear transcription factor kappa-B. | Toxicology letters 20181001 |
| Ovatodiolide suppresses yes-associated protein 1-modulated cancer stem cell phenotypes in highly malignant hepatocellular carcinoma and sensitizes cancer cells to chemotherapy in vitro. | Toxicology in vitro : an international journal published in association with BIBRA 20180901 |
| Flavan enantiomers from Daphne giraldii selectively induce apoptotic cell death in p53-null hepatocarcinoma cells in vitro. | Chemico-biological interactions 20180601 |
| Lenvatinib versus sorafenib in first-line treatment of patients with unresectable hepatocellular carcinoma: a randomised phase 3 non-inferiority trial. | Lancet (London, England) 20180324 |
| Mechanisms of mitochondrial toxicity of the kinase inhibitors ponatinib, regorafenib and sorafenib in human hepatic HepG2 cells. | Toxicology 20180215 |
| Sorafenib targets the mitochondrial electron transport chain complexes and ATP synthase to activate the PINK1-Parkin pathway and modulate cellular drug response. | The Journal of biological chemistry 20170908 |
| 3-Acetylpyridine neurotoxicity in mice. | Neurotoxicology 20170101 |
| A novel JAK inhibitor, peficitinib, demonstrates potent efficacy in a rat adjuvant-induced arthritis model. | Journal of pharmacological sciences 20170101 |
| Over-the-counter treatments for acne and rosacea. | Seminars in cutaneous medicine and surgery 20160601 |
| 5-((3-Amidobenzyl)oxy)nicotinamides as Sirtuin 2 Inhibitors. | Journal of medicinal chemistry 20160414 |
| Nilotinib reduced the viability of human ovarian cancer cells via mitochondria-dependent apoptosis, independent of JNK activation. | Toxicology in vitro : an international journal published in association with BIBRA 20160301 |
| Resveratrol attenuates constitutive STAT3 and STAT5 activation through induction of PTPε and SHP-2 tyrosine phosphatases and potentiates sorafenib-induced apoptosis in renal cell carcinoma. | BMC nephrology 20160101 |
| Inhibition of IKKα by BAY61-3606 Reveals IKKα-Dependent Histone H3 Phosphorylation in Human Cytomegalovirus Infected Cells. | PloS one 20160101 |
| New Approach for Treatment of Primary Liver Tumors: The Role of Quercetin. | Nutrition and cancer 20160101 |
| Growth arrest DNA damage-inducible gene 45 gamma expression as a prognostic and predictive biomarker in hepatocellular carcinoma. | Oncotarget 20150929 |
| A phase 2a randomized, double-blind, placebo-controlled, sequential dose-escalation study to evaluate the efficacy and safety of ASP015K, a novel Janus kinase inhibitor, in patients with moderate-to-severe psoriasis. | The British journal of dermatology 20150901 |
| The HSP90 inhibitor alvespimycin enhances the potency of telomerase inhibition by imetelstat in human osteosarcoma. | Cancer biology & therapy 20150601 |
| Resveratrol activates duodenal Sirt1 to reverse insulin resistance in rats through a neuronal network. | Nature medicine 20150501 |
| Arsenic trioxide potentiates the anti-cancer activities of sorafenib against hepatocellular carcinoma by inhibiting Akt activation. | Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20150401 |
| Downregulation of stanniocalcin 1 is responsible for sorafenib-induced cardiotoxicity. | Toxicological sciences : an official journal of the Society of Toxicology 20150201 |
| Combinatorial chemopreventive effect of butyric acid, nicotinamide and calcium glucarate against the 7,12-dimethylbenz(a)anthracene induced mouse skin tumorigenesis attained by enhancing the induction of intrinsic apoptotic events. | Chemico-biological interactions 20150125 |
| Cytochrome P450-Mediated Biotransformation of Sorafenib and Its N-Oxide Metabolite: Implications for Cell Viability and Human Toxicity. | Chemical research in toxicology 20150120 |
| G-protein-coupled bile acid receptor 1 (GPBAR1, TGR5) agonists reduce the production of proinflammatory cytokines and stabilize the alternative macrophage phenotype. | Journal of medicinal chemistry 20141226 |
| Discovery of 2-[5-(4-Fluorophenylcarbamoyl)pyridin-2-ylsulfanylmethyl]phenylboronic Acid (SX-517): Noncompetitive Boronic Acid Antagonist of CXCR1 and CXCR2. | Journal of medicinal chemistry 20141023 |
| Discovery of potent and selective sirtuin 2 (SIRT2) inhibitors using a fragment-based approach. | Journal of medicinal chemistry 20141023 |
| Sirtuin-1 (SIRT1) is required for promoting chondrogenic differentiation of mesenchymal stem cells. | The Journal of biological chemistry 20140808 |
| Sirtuin 1-mediated inhibition of p66shc expression alleviates liver ischemia/reperfusion injury. | Critical care medicine 20140501 |
| Preclinical evaluation of AMG 925, a FLT3/CDK4 dual kinase inhibitor for treating acute myeloid leukemia. | Molecular cancer therapeutics 20140401 |
| HSF1 protects neurons through a novel trimerization- and HSP-independent mechanism. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20140129 |
| Resveratrol, an activator of SIRT1, upregulates AMPK and improves cardiac function in heart failure. | Genetics and molecular research : GMR 20140121 |
| Precision-cut liver slices as a model for the early onset of liver fibrosis to test antifibrotic drugs. | Toxicology and applied pharmacology 20140115 |
| Pentamethylquercetin reduces fat deposition via Sirt1-mediated pathways in male obese mice induced by a high fat diet. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20131201 |
| Pharmacological characterization of a novel centrally permeable P2X7 receptor antagonist: JNJ-47965567. | British journal of pharmacology 20131001 |
| Mechanism of MEK inhibition determines efficacy in mutant KRAS- versus BRAF-driven cancers. | Nature 20130912 |
| LY2801653 is an orally bioavailable multi-kinase inhibitor with potent activity against MET, MST1R, and other oncoproteins, and displays anti-tumor activities in mouse xenograft models. | Investigational new drugs 20130801 |
| Synergistic interactions between sorafenib and everolimus in pancreatic cancer xenografts in mice. | Cancer chemotherapy and pharmacology 20130501 |
| Simultaneous analysis of anticancer agents bortezomib, imatinib, nilotinib, dasatinib, erlotinib, lapatinib, sorafenib, sunitinib and vandetanib in human plasma using LC/MS/MS. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20130501 |
| Oral L-glutamine increases active GLP-1 (7-36) amide secretion and improves glycemic control in stretpozotocin-nicotinamide induced diabetic rats. | Chemico-biological interactions 20130425 |
| Unique signaling profiles of positive allosteric modulators of metabotropic glutamate receptor subtype 5 determine differences in in vivo activity. | Biological psychiatry 20130315 |
| Catalytic contribution of threonine 244 in human ALDH2. | Chemico-biological interactions 20130225 |
| Mechanisms of apoptosis induction by simultaneous inhibition of PI3K and FLT3-ITD in AML cells in the hypoxic bone marrow microenvironment. | Cancer letters 20130201 |
| Mitochondrial inhibitor models of Huntington's disease and Parkinson's disease induce zinc accumulation and are attenuated by inhibition of zinc neurotoxicity in vitro or in vivo. | Neuro-degenerative diseases 20130101 |
| Targeted agents and systemic therapy in hepatocellular carcinoma. | Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20130101 |
| The Enhanced metastatic potential of hepatocellular carcinoma (HCC) cells with sorafenib resistance. | PloS one 20130101 |
| EGFR activation is a potential determinant of primary resistance of hepatocellular carcinoma cells to sorafenib. | International journal of cancer 20121215 |
| Enhancement of tacrolimus productivity in Streptomyces tsukubaensis by the use of novel precursors for biosynthesis. | Enzyme and microbial technology 20121210 |
| Plasma protein binding of sorafenib, a multi kinase inhibitor: in vitro and in cancer patients. | Investigational new drugs 20121201 |
| Sorafenib in patients with metastatic gastrointestinal stromal tumors who failed two or more prior tyrosine kinase inhibitors: a phase II study of Korean gastrointestinal stromal tumors study group. | Investigational new drugs 20121201 |
| Phase II study of bevacizumab and erlotinib in the treatment of advanced hepatocellular carcinoma patients with sorafenib-refractory disease. | Investigational new drugs 20121201 |
| Gemcitabine and oxaliplatin as second-line treatment in patients with hepatocellular carcinoma pre-treated with sorafenib. | Medical oncology (Northwood, London, England) 20121201 |
| Negative transcriptional regulation of inflammatory genes by group B3 vitamin nicotinamide. | Molecular biology reports 20121201 |
| Extrahepatic spread of hepatocellular carcinoma. | Panminerva medica 20121201 |
| Coformer selection based on degradation pathway of drugs: a case study of adefovir dipivoxil-saccharin and adefovir dipivoxil-nicotinamide cocrystals. | International journal of pharmaceutics 20121115 |
| Rationally designed aberrant kinase-targeted endogenous protein nanomedicine against oncogene mutated/amplified refractory chronic myeloid leukemia. | Molecular pharmaceutics 20121105 |
| Suppression of electron transfer to dioxygen by charge transfer and electron transfer complexes in the FAD-dependent reductase component of toluene dioxygenase. | The Journal of biological chemistry 20121102 |
| Structural diversity of new C13-polyketides produced by Chaetomium mollipilium cultivated in the presence of a NAD(+)-dependent histone deacetylase inhibitor. | Organic letters 20121102 |
| Different effects of histone deacetylase inhibitors nicotinamide and trichostatin A (TSA) in C17.2 neural stem cells. | Journal of neural transmission (Vienna, Austria : 1996) 20121101 |
| The effects of sorafenib on liver regeneration in a model of partial hepatectomy. | The Journal of surgical research 20121101 |
| Sorafenib and bevacizumab for recurrent metastatic hepatoblastoma: stable radiographic disease with decreased AFP. | Pediatric blood & cancer 20121101 |
| The use of single-agent sorafenib in the treatment of advanced hepatocellular carcinoma patients with underlying Child-Pugh B liver cirrhosis: a retrospective analysis of efficacy, safety, and survival benefits. | Cancer 20121101 |
| Pyridine metabolism in tea plants: salvage, conjugate formation and catabolism. | Journal of plant research 20121101 |
| A phase I multi-institutional study of systemic sorafenib in conjunction with regional melphalan for in-transit melanoma of the extremity. | Annals of surgical oncology 20121101 |
| The sorafenib plus nutlin-3 combination promotes synergistic cytotoxicity in acute myeloid leukemic cells irrespectively of FLT3 and p53 status. | Haematologica 20121101 |
| Structural, spectroscopic and voltammetric studies of bis(acetazolamido)bis(aquo)bis(nicotinamide)copper(II). | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121101 |
| BAYPAN study: a double-blind phase III randomized trial comparing gemcitabine plus sorafenib and gemcitabine plus placebo in patients with advanced pancreatic cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20121101 |
| MCM7 expression predicts post-operative prognosis for hepatocellular carcinoma. | Liver international : official journal of the International Association for the Study of the Liver 20121101 |
| Rapid determination of thiamine, riboflavin, niacinamide, pantothenic acid, pyridoxine, folic acid and ascorbic acid in Vitamins with Minerals Tablets by high-performance liquid chromatography with diode array detector. | Journal of pharmaceutical and biomedical analysis 20121101 |
| Pneumatosis intestinalis and hepatic portal venous gas in a patient receiving sorafenib. | International journal of urology : official journal of the Japanese Urological Association 20121101 |
| Sorafenib attenuates monocrotaline-induced sinusoidal obstruction syndrome in rats through suppression of JNK and MMP-9. | Journal of hepatology 20121101 |
| Rho-kinase-dependent pathway mediates the hepatoprotective effects of sorafenib against ischemia/reperfusion liver injury in rats with nonalcoholic steatohepatitis. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20121101 |
| High toxicity of sorafenib for recurrent hepatocellular carcinoma after liver transplantation. | Transplant international : official journal of the European Society for Organ Transplantation 20121101 |
| Simulations using a drug-disease modeling framework and phase II data predict phase III survival outcome in first-line non-small-cell lung cancer. | Clinical pharmacology and therapeutics 20121101 |
| Long-term analysis of the efficacy and tolerability of sorafenib in advanced radio-iodine refractory differentiated thyroid carcinoma: final results of a phase II trial. | European journal of endocrinology 20121101 |
| The methanolic fraction of Centratherum anthelminticum seed downregulates pro-inflammatory cytokines, oxidative stress, and hyperglycemia in STZ-nicotinamide-induced type 2 diabetic rats. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20121101 |
| Evaluation of changes in the tumor microenvironment after sorafenib therapy by sequential histology and 18F-fluoromisonidazole hypoxia imaging in renal cell carcinoma. | International journal of oncology 20121101 |
| Comparison of the formation of nicotinic acid conjugates in leaves of different plant species. | Plant physiology and biochemistry : PPB 20121101 |
| Design, synthesis and biological activities of sorafenib derivatives as antitumor agents. | Bioorganic & medicinal chemistry letters 20121101 |
| N-methylnicotinamide is an endogenous probe for evaluation of drug-drug interactions involving multidrug and toxin extrusions (MATE1 and MATE2-K). | Clinical pharmacology and therapeutics 20121101 |
| Clinical outcomes and biomarker profiles of elderly pretreated NSCLC patients from the BATTLE trial. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20121101 |
| A novel combination therapy approach for the treatment of acute myeloid leukemia: the multi-kinase inhibitor sorafenib and the HDM2 inhibitor nutlin-3. | Haematologica 20121101 |
| Ontogeny and sorafenib metabolism. | Clinical cancer research : an official journal of the American Association for Cancer Research 20121015 |
| Sorafenib inhibits hypoxia-inducible factor-1α synthesis: implications for antiangiogenic activity in hepatocellular carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20121015 |
| Expression patterns of sirtuin genes in porcine preimplantation embryos and effects of sirtuin inhibitors on in vitro embryonic development after parthenogenetic activation and in vitro fertilization. | Theriogenology 20121015 |
| Optimization of an ether series of mGlu5 positive allosteric modulators: molecular determinants of MPEP-site interaction crossover. | Bioorganic & medicinal chemistry letters 20121015 |
| Metabolomic signatures in guinea pigs infected with epidemic-associated W-Beijing strains of Mycobacterium tuberculosis. | Journal of proteome research 20121005 |
| Saturable absorption of sorafenib in patients with solid tumors: a population model. | Investigational new drugs 20121001 |
| Feasibility study of intra-patient sorafenib dose-escalation or re-escalation in patients with previously treated advanced solid tumors. | Investigational new drugs 20121001 |
| Sorafenib exposure decreases over time in patients with hepatocellular carcinoma. | Investigational new drugs 20121001 |
| Sorafenib as treatment for relapsed or refractory pediatric acute myelogenous leukemia. | Pediatric blood & cancer 20121001 |
| Sorafenib inhibits neuroblastoma cell proliferation and signaling, blocks angiogenesis, and impairs tumor growth. | Pediatric blood & cancer 20121001 |
| Partial response of angiosarcoma of the scalp to sorafenib: association with decreased expression of vascular endothelial growth factors and their receptors. | Clinical and experimental dermatology 20121001 |
| Blockade of the brain histamine H3 receptor by JNJ-39220675: preclinical PET studies with [¹¹C]GSK189254 in anesthetized baboon. | Psychopharmacology 20121001 |
| Neoadjuvant therapy of renal cell carcinoma: a novel treatment option in the era of targeted therapy? | International journal of urology : official journal of the Japanese Urological Association 20121001 |
| Tumor reoxygenation following administration of Mitogen-Activated Protein Kinase inhibitors: a rationale for combination with radiation therapy. | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20121001 |
| Efficacy and safety of sorafenib in patients with advanced hepatocellular carcinoma: subanalyses of a phase III trial. | Journal of hepatology 20121001 |
| Antagonism of supraspinal histamine H3 receptors modulates spinal neuronal activity in neuropathic rats. | The Journal of pharmacology and experimental therapeutics 20121001 |
| Sorafenib for lung cancer: is the 'Battle' still open? | Expert opinion on investigational drugs 20121001 |
| Regression of hepatocellular carcinoma with right atrial extension after sorafenib and transarterial chemoembolization. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20121001 |
| Sorafenib-induced hepatocellular carcinoma cell death depends on reactive oxygen species production in vitro and in vivo. | Molecular cancer therapeutics 20121001 |
| MicroR828 regulates lignin and H2O2 accumulation in sweet potato on wounding. | The New phytologist 20121001 |
| Phenethyl nicotinamides, a novel class of Na(V)1.7 channel blockers: structure and activity relationship. | Bioorganic & medicinal chemistry letters 20121001 |
| The important roles of RET, VEGFR2 and the RAF/MEK/ERK pathway in cancer treatment with sorafenib. | Acta pharmacologica Sinica 20121001 |
| Sunitinib- and sorafenib-induced nephrotic syndrome in a patient with gastrointestinal stromal tumor. | The Annals of pharmacotherapy 20121001 |
| Sorafenib in treatment of patients with advanced hepatocellular carcinoma: a systematic review. | Hepatobiliary & pancreatic diseases international : HBPD INT 20121001 |
| Synergistic antitumor efficacy of sequentially combined paclitaxel with sorafenib in vitro and in vivo NSCLC models harboring KRAS or BRAF mutations. | Cancer letters 20120928 |
| An adaptive Src-PDGFRA-Raf axis in rhabdomyosarcoma. | Biochemical and biophysical research communications 20120928 |
| A case of reversible cardiomyopathy associated with sorafenib in advanced hepatocellular carcinoma. | International journal of cardiology 20120920 |
| Jedi-1 and MEGF10 signal engulfment of apoptotic neurons through the tyrosine kinase Syk. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20120919 |
| Heme oxygenase-1 promotes survival of renal cancer cells through modulation of apoptosis- and autophagy-regulating molecules. | The Journal of biological chemistry 20120914 |
| Spleen tyrosine kinase mediates high glucose-induced transforming growth factor-β1 up-regulation in proximal tubular epithelial cells. | Experimental cell research 20120910 |
| Transcription levels of sirtuin family in neural stem cells and brain tissues of adult mice. | Cellular and molecular biology (Noisy-le-Grand, France) 20120910 |
| FLT3-ITD knockin impairs hematopoietic stem cell quiescence/homeostasis, leading to myeloproliferative neoplasm. | Cell stem cell 20120907 |
| C/EBPε mediates nicotinamide-enhanced clearance of Staphylococcus aureus in mice. | The Journal of clinical investigation 20120904 |
| Thyroid size change by CT monitoring after sorafenib or sunitinib treatment in patients with renal cell carcinoma: comparison with thyroid function. | European journal of radiology 20120901 |
| Proteome analysis of the effects of sorafenib on human hepatocellular carcinoma cell line HepG2. | Medical oncology (Northwood, London, England) 20120901 |
| Sequential use of sorafenib and sunitinib in advanced renal cell carcinoma: does the order of sequencing matter? | Medical oncology (Northwood, London, England) 20120901 |
| Course of size and density of metastatic renal cell carcinoma lesions in the early follow-up of molecular targeted therapy. | Urologic oncology 20120901 |
| N-Methyl-2-pyridone-5-carboxamide is 1-methylnicotinamide metabolite of low cyclooxygenase-dependent vasodilating activity. | Journal of physiology and biochemistry 20120901 |
| Toxic effects of nicotinamide methylation on mouse brain striatum neuronal cells and its relation to manganese. | Environmental health and preventive medicine 20120901 |
| Sorafenib rechallenge in patients with metastatic renal cell carcinoma. | BJU international 20120901 |
| Sorafenib rechalenge in metastatic renal cell carcinoma. | BJU international 20120901 |
| K-Ras mutation-mediated IGF-1-induced feedback ERK activation contributes to the rapalog resistance in pancreatic ductal adenocarcinomas. | Cancer letters 20120901 |
| Use of tyrosine kinase inhibitors in patients with metastatic kidney cancer receiving haemodialysis: a retrospective Italian survey. | BJU international 20120901 |
| Portal hemodynamic effects of sorafenib in patients with advanced hepatocellular carcinoma: a prospective cohort study. | Journal of gastroenterology 20120901 |
| NAD(+) biosynthesis and salvage--a phylogenetic perspective. | The FEBS journal 20120901 |
| Inhibitory activity of ranibizumab, sorafenib, and pazopanib on light-induced overexpression of platelet-derived growth factor and vascular endothelial growth factor A and the vascular endothelial growth factor A receptors 1 and 2 and neuropilin 1 and 2. | Retina (Philadelphia, Pa.) 20120901 |
| Physicochemical characterization and structural evaluation of a specific 2:1 cocrystal of naproxen-nicotinamide. | Journal of pharmaceutical sciences 20120901 |
| A phase II trial of intrapatient dose-escalated sorafenib in patients with metastatic renal cell carcinoma. | Clinical genitourinary cancer 20120901 |
| Occurrence of boscalid and other selected fungicides in surface water and groundwater in three targeted use areas in the United States. | Chemosphere 20120901 |
| Safety and effectiveness of sorafenib in patients with hepatocellular carcinoma in clinical practice. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20120901 |
| Erlotinib and sorafenib in an orthotopic rat model of hepatocellular carcinoma. | Journal of hepatology 20120901 |
| Sorafenib enhances the therapeutic efficacy of rapamycin in colorectal cancers harboring oncogenic KRAS and PIK3CA. | Carcinogenesis 20120901 |
| Nicotinamide reduces photodynamic therapy-induced immunosuppression in humans. | The British journal of dermatology 20120901 |
| Primary renal cell carcinoma: relationship between 18F-FDG uptake and response to neoadjuvant sorafenib. | Nuclear medicine communications 20120901 |
| Unusual short-term complete response to two regimens of cytotoxic chemotherapy in a patient with poorly differentiated thyroid carcinoma. | The Journal of clinical endocrinology and metabolism 20120901 |
| Sorafenib in non-small cell lung cancer. | Expert opinion on investigational drugs 20120901 |
| Variability of sorafenib toxicity and exposure over time: a pharmacokinetic/pharmacodynamic analysis. | The oncologist 20120901 |
| Erythema multiforme induced by sorafenib for metastatic renal cell carcinoma. | Japanese journal of clinical oncology 20120901 |
| Identification of a sirtuin 3 inhibitor that displays selectivity over sirtuin 1 and 2. | European journal of medicinal chemistry 20120901 |
| Phase III, randomized, double-blind, placebo-controlled trial of gemcitabine/cisplatin alone or with sorafenib for the first-line treatment of advanced, nonsquamous non-small-cell lung cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120901 |
| Discovery of novel 2-aminopyridine-3-carboxamides as c-Met kinase inhibitors. | Bioorganic & medicinal chemistry 20120901 |
| Blockade of STAT3 activation by sorafenib derivatives through enhancing SHP-1 phosphatase activity. | European journal of medicinal chemistry 20120901 |
| Treatment of hepatocellular carcinoma with sorafenib - focus on special populations and adverse event management. | Zeitschrift fur Gastroenterologie 20120901 |
| Sorafenib for the treatment of recurrent hepatocellular carcinoma after liver transplantation? | Transplantation proceedings 20120901 |
| Hepatic arterial thrombosis: a critical complication during combination therapy of arterial chemoinfusion and sorafenib. | Anticancer research 20120901 |
| Inhibitors of B-cell receptor signaling for patients with B-cell malignancies. | Cancer journal (Sudbury, Mass.) 20120901 |
| [Nintedanib (BIBF 1120) in the treatment of solid cancers: an overview of biological and clinical aspects]. | Magyar onkologia 20120901 |
| Synergistic growth inhibition by sorafenib and vitamin K2 in human hepatocellular carcinoma cells. | Clinics (Sao Paulo, Brazil) 20120901 |
| Structure-based virtual screening and identification of a novel androgen receptor antagonist. | The Journal of biological chemistry 20120831 |
| Ultra-performance liquid chromatography tandem mass-spectrometry (UPLC-MS/MS) for the rapid, simultaneous analysis of thiamin, riboflavin, flavin adenine dinucleotide, nicotinamide and pyridoxal in human milk. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120815 |
| International, randomized, placebo-controlled, double-blind phase III study of motesanib plus carboplatin/paclitaxel in patients with advanced nonsquamous non-small-cell lung cancer: MONET1. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120810 |
| Sorafenib use in hepatocellular carcinoma in Japan: early experience and impact on clinical practice. | Clinical drug investigation 20120808 |
| Current status of hepatocellular carcinoma treatment in Japan: transarterial chemoembolization. | Clinical drug investigation 20120808 |
| Current status of hepatocellular carcinoma treatment in Japan: hepatic arterial infusion chemotherapy. | Clinical drug investigation 20120808 |
| Current status of hepatocellular carcinoma treatment in Japan: practical use of sorafenib (Nexavar®). | Clinical drug investigation 20120808 |
| Current status of hepatocellular carcinoma treatment in Japan: case study and discussion-voting system. | Clinical drug investigation 20120808 |
| Phase I study investigating the safety and feasibility of combining imatinib mesylate (Gleevec) with sorafenib in patients with refractory castration-resistant prostate cancer. | British journal of cancer 20120807 |
| Phase 1 trial of S-1 in combination with sorafenib for patients with advanced hepatocellular carcinoma. | Investigational new drugs 20120801 |
| Sequential therapy with sunitinib and sorafenib in metastatic hepatocellular carcinoma. | Investigational new drugs 20120801 |
| SWOG 0514: a phase II study of sorafenib in patients with unresectable or metastatic gallbladder carcinoma and cholangiocarcinoma. | Investigational new drugs 20120801 |
| A phase II study of sorafenib in combination with bicalutamide in patients with chemotherapy-naive castration resistant prostate cancer. | Investigational new drugs 20120801 |
| Synergistic effects of the combination of β-ionone and sorafenib on metastasis of human hepatoma SK-Hep-1 cells. | Investigational new drugs 20120801 |
| Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma. | International journal of cancer 20120801 |
| Management of hepatocellular carcinoma with transarterial chemoembolization in the era of systemic targeted therapy. | Critical reviews in oncology/hematology 20120801 |
| Development and validation of a prediction index for hand-foot skin reaction in cancer patients receiving sorafenib. | Annals of oncology : official journal of the European Society for Medical Oncology 20120801 |
| PKI-587 and sorafenib targeting PI3K/AKT/mTOR and Ras/Raf/MAPK pathways synergistically inhibit HCC cell proliferation. | The Journal of surgical research 20120801 |
| Inhibition of corneal neovascularization in rats by systemic administration of sorafenib. | Cornea 20120801 |
| Nicotinamide treatment reduces the levels of histone H3K4 trimethylation in the promoter of the mper1 circadian clock gene and blocks the ability of dexamethasone to induce the acute response. | Biochimica et biophysica acta 20120801 |
| New use for an old drug: inhibiting ABCG2 with sorafenib. | Molecular cancer therapeutics 20120801 |
| Differential drug class-specific metastatic effects following treatment with a panel of angiogenesis inhibitors. | The Journal of pathology 20120801 |
| Sorafenib in locally advanced or metastatic breast cancer. | Expert opinion on investigational drugs 20120801 |
| Thyroid dysfunction in patients treated with tyrosine kinase inhibitors, sunitinib, sorafenib and axitinib, for metastatic renal cell carcinoma. | Japanese journal of clinical oncology 20120801 |
| Combination of the ERK inhibitor AZD6244 and low-dose sorafenib in a xenograft model of human renal cell carcinoma. | International journal of oncology 20120801 |
| Sorafenib inhibits many kinase mutations associated with drug-resistant gastrointestinal stromal tumors. | Molecular cancer therapeutics 20120801 |
| Combination of sorafenib and everolimus impacts therapeutically on adrenocortical tumor models. | Endocrine-related cancer 20120801 |
| Use of Sorafenib as an effective treatment in an AML patient carrying a new point mutation affecting the Juxtamembrane domain of FLT3. | British journal of haematology 20120801 |
| Phase I study of sorafenib in combination with docetaxel and prednisone in chemo-naïve patients with metastatic castration-resistant prostate cancer. | Cancer chemotherapy and pharmacology 20120801 |
| Brain metastasis from follicular thyroid carcinoma: treatment with sorafenib. | Thyroid : official journal of the American Thyroid Association 20120801 |
| Molecular mechanisms of sorafenib action in liver cancer cells. | Cell cycle (Georgetown, Tex.) 20120801 |
| Protective effect of Luffa acutangula extracts on gastric ulceration in NIDDM rats: role of gastric mucosal glycoproteins and antioxidants. | Asian Pacific journal of tropical medicine 20120801 |
| Targeting angiogenesis in metastatic breast cancer. | The oncologist 20120801 |
| HDAC inhibitors synergize antiproliferative effect of sorafenib in renal cell carcinoma cells. | Anticancer research 20120801 |
| The aqueous extract of Withania coagulans fruit partially reverses nicotinamide/streptozotocin-induced diabetes mellitus in rats. | Journal of medicinal food 20120801 |
| Novel antiangiogenic therapies against advanced hepatocellular carcinoma (HCC). | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20120801 |
| Favorable effect of sorafenib in a patient with neurofibromatosis-associated pulmonary hypertension. | American journal of respiratory and critical care medicine 20120801 |
| [Current status and future perspective of sorafenib for advanced hepatocellular carcinoma]. | Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20120801 |
| Phase 1b dose-finding study of motesanib with docetaxel or paclitaxel in patients with metastatic breast cancer. | Breast cancer research and treatment 20120801 |
| The effect of sorafenib treatment on the diabetic status of patients with renal cell or hepatocellular carcinoma. | Future oncology (London, England) 20120801 |
| Impact of restricting access to high-cost medications for hepatocellular carcinoma. | Expert review of pharmacoeconomics & outcomes research 20120801 |
| [A case of fatal clinical course with reversible acute cardiac failure and glucose intolerance during sorafenib therapy for metastatic renal cell carcinoma]. | Hinyokika kiyo. Acta urologica Japonica 20120801 |
| ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation. | Nature 20120725 |
| Sorafenib in advanced melanoma: a critical role for pharmacokinetics? | British journal of cancer 20120724 |
| Preliminary experience with personalized and targeted therapy for pediatric brain tumors. | Pediatric blood & cancer 20120715 |
| Role of human CYP3A4 in the biotransformation of sorafenib to its major oxidized metabolites. | Biochemical pharmacology 20120715 |
| Combining antiangiogenics to overcome resistance: rationale and clinical experience. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120715 |
| A new facile synthetic route to [11C]GSK189254, a selective PET radioligand for imaging of CNS histamine H3 receptor. | Bioorganic & medicinal chemistry letters 20120715 |
| Design, synthesis and antitumor activities of novel bis-aryl ureas derivatives as Raf kinase inhibitors. | Bioorganic & medicinal chemistry 20120715 |
| Efficient differentiation of AR42J cells towards insulin-producing cells using pancreatic transcription factors in combination with growth factors. | Molecular and cellular endocrinology 20120706 |
| Role of deleted in breast cancer 1 (DBC1) protein in SIRT1 deacetylase activation induced by protein kinase A and AMP-activated protein kinase. | The Journal of biological chemistry 20120706 |
| GSK-3 inhibition in vitro and in vivo enhances antitumor effect of sorafenib in renal cell carcinoma (RCC). | Biochemical and biophysical research communications 20120706 |
| Multikinase inhibitor sorafenib transiently promotes necrosis after radiofrequency ablation in rat liver but activates growth signals. | European journal of radiology 20120701 |
| Angiostatic kinase inhibitors to sustain photodynamic angio-occlusion. | Journal of cellular and molecular medicine 20120701 |
| Multiple kinase pathways involved in the different de novo sensitivity of pancreatic cancer cell lines to 17-AAG. | The Journal of surgical research 20120701 |
| Efficacy and safety of sorafenib in patients with advanced hepatocellular carcinoma according to baseline status: subset analyses of the phase III Sorafenib Asia-Pacific trial. | European journal of cancer (Oxford, England : 1990) 20120701 |
| Dasatinib synergizes with both cytotoxic and signal transduction inhibitors in heterogeneous breast cancer cell lines--lessons for design of combination targeted therapy. | Cancer letters 20120701 |
| Further studies on the hypothesis of PARP-1 inhibition as a strategy for lessening the long-term effects produced by perinatal asphyxia: effects of nicotinamide and theophylline on PARP-1 activity in brain and peripheral tissue : nicotinamide and theophylline on PARP-1 activity. | Neurotoxicity research 20120701 |
| Targeted therapy for biliary tract cancers. | Journal of hepato-biliary-pancreatic sciences 20120701 |
| Hepatic androgen receptor suppresses hepatocellular carcinoma metastasis through modulation of cell migration and anoikis. | Hepatology (Baltimore, Md.) 20120701 |
| Selective FLT3 inhibition of FLT3-ITD+ acute myeloid leukaemia resulting in secondary D835Y mutation: a model for emerging clinical resistance patterns. | Leukemia 20120701 |
| Simultaneously improving the mechanical properties, dissolution performance, and hygroscopicity of ibuprofen and flurbiprofen by cocrystallization with nicotinamide. | Pharmaceutical research 20120701 |
| A maxillary mass in a HBV-cirrhotic patient. | Liver international : official journal of the International Association for the Study of the Liver 20120701 |
| Usefulness of alpha-fetoprotein response in patients treated with sorafenib for advanced hepatocellular carcinoma. | Journal of hepatology 20120701 |
| Epidermal growth factor receptor and HER-3 restrict cell response to sorafenib in hepatocellular carcinoma cells. | Journal of hepatology 20120701 |
| Clinical course of sorafenib treatment in patients with hepatocellular carcinoma. | Scandinavian journal of gastroenterology 20120701 |
| RAIN-Droplet: a novel 3D in vitro angiogenesis model. | Laboratory investigation; a journal of technical methods and pathology 20120701 |
| Phase II study of sorafenib in patients with relapsed or refractory lymphoma. | British journal of haematology 20120701 |
| Sorafenib and pemetrexed toxicity in cancer cells is mediated via SRC-ERK signaling. | Cancer biology & therapy 20120701 |
| First interim analysis of the GIDEON (Global Investigation of therapeutic decisions in hepatocellular carcinoma and of its treatment with sorafeNib) non-interventional study. | International journal of clinical practice 20120701 |
| Selective internal radiation therapy of hepatocellular carcinoma: potential hepatopulmonary shunt reduction after sorafenib administration. | Journal of vascular and interventional radiology : JVIR 20120701 |
| The role of PI3K/mTOR inhibition in combination with sorafenib in hepatocellular carcinoma treatment. | Anticancer research 20120701 |
| A 1:1 cocrystal of baicalein with nicotinamide. | Acta crystallographica. Section C, Crystal structure communications 20120701 |
| [Influence of body surface area on efficacy and safety of sorafenib in advanced hepatocellular carcinoma]. | Gan to kagaku ryoho. Cancer & chemotherapy 20120701 |
| Copy number aberrations of BCL2 and CDKN2A/B identified by array-CGH in thymic epithelial tumors. | Cell death & disease 20120701 |
| Long-term results of sorafenib in advanced-stage hepatocellular carcinoma: what can we learn from routine clinical practice? | Expert review of anticancer therapy 20120701 |
| Influence of the sorafenib patients assistance program on treatment compliance and overall survival of unresectable hepatocellular carcinoma patients. | Acta medica Indonesiana 20120701 |
| In vivo evaluation of an oral drug delivery system for peptides based on S-protected thiolated chitosan. | Journal of controlled release : official journal of the Controlled Release Society 20120628 |
| Unusual co-crystal of isonicotinamide: the structural landscape in crystal engineering. | Philosophical transactions. Series A, Mathematical, physical, and engineering sciences 20120628 |
| Discovery of a potent, selective, and orally bioavailable acidic 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor: discovery of 2-[(3S)-1-[5-(cyclohexylcarbamoyl)-6-propylsulfanylpyridin-2-yl]-3-piperidyl]acetic acid (AZD4017). | Journal of medicinal chemistry 20120628 |
| Life beyond kinases: structure-based discovery of sorafenib as nanomolar antagonist of 5-HT receptors. | Journal of medicinal chemistry 20120628 |
| Inhibition of nicotinamide phosphoribosyltransferase (NAMPT) activity by small molecule GMX1778 regulates reactive oxygen species (ROS)-mediated cytotoxicity in a p53- and nicotinic acid phosphoribosyltransferase1 (NAPRT1)-dependent manner. | The Journal of biological chemistry 20120622 |
| Inhibition of Bcl-2 antiapoptotic members by obatoclax potently enhances sorafenib-induced apoptosis in human myeloid leukemia cells through a Bim-dependent process. | Blood 20120621 |
| Safety and pharmacokinetics of ganitumab (AMG 479) combined with sorafenib, panitumumab, erlotinib, or gemcitabine in patients with advanced solid tumors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120615 |
| Isonicotinamide enhances Sir2 protein-mediated silencing and longevity in yeast by raising intracellular NAD+ concentration. | The Journal of biological chemistry 20120615 |
| Neutrophil recruitment is inhibited by nicotinamide in experimental pleurisy in mice. | European journal of pharmacology 20120615 |
| Synthesis, biological evaluation and 3D-QSAR studies of novel 4,5-dihydro-1H-pyrazole niacinamide derivatives as BRAF inhibitors. | Bioorganic & medicinal chemistry 20120615 |
| Combined anti-tumor effects of IFN-α and sorafenib on hepatocellular carcinoma in vitro and in vivo. | Biochemical and biophysical research communications 20120615 |
| Chemical genetic discovery of targets and anti-targets for cancer polypharmacology. | Nature 20120606 |
| The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity. | Cell metabolism 20120606 |
| Clusterin inhibition using OGX-011 synergistically enhances antitumour activity of sorafenib in a human renal cell carcinoma model. | British journal of cancer 20120605 |
| Activation of JNK and high expression level of CD133 predict a poor response to sorafenib in hepatocellular carcinoma. | British journal of cancer 20120605 |
| Sorafenib and radiation therapy for the treatment of advanced hepatocellular carcinoma. | Journal of gastrointestinal cancer 20120601 |
| Phase I trial of sorafenib in combination with interferon-alpha in Japanese patients with unresectable or metastatic renal cell carcinoma. | Investigational new drugs 20120601 |
| Sorafenib versus cytotoxic chemotherapy for patients with advanced hepatocellular carcinoma: a retrospective, single-institution study. | Investigational new drugs 20120601 |
| Sequential treatment with sorafenib and sunitinib in metastatic renal cell carcinoma: clinical outcomes from a retrospective clinical study. | Medical oncology (Northwood, London, England) 20120601 |
| A randomized phase II of gemcitabine and sorafenib versus sorafenib alone in patients with metastatic pancreatic cancer. | Investigational new drugs 20120601 |
| Safety and treatment patterns of angiogenesis inhibitors in patients with metastatic renal cell carcinoma: evidence from US community oncology clinics. | Medical oncology (Northwood, London, England) 20120601 |
| Langerhans cell histiocytosis with central nervous system involvement--complete response to 2-chlorodeoxyadenosine after failure of tyrosine kinase inhibitor therapies with sorafenib and imatinib. | Hematological oncology 20120601 |
| Donor erythrocytosis induced by sorafenib treatment after allogeneic hematopoietic SCT in a patient with acute myeloid leukemia. | Bone marrow transplantation 20120601 |
| Early detection, prevention and management of cutaneous adverse events due to sorafenib: recommendations from the Sorafenib Working Group. | Critical reviews in oncology/hematology 20120601 |
| Sorafenib in hepatocellular carcinoma - a post marketing evaluation. | Immunopharmacology and immunotoxicology 20120601 |
| Survey and analysis of the efficacy and prescription pattern of sorafenib in patients with acute myeloid leukemia. | Leukemia & lymphoma 20120601 |
| Primary anti-vascular endothelial growth factor (VEGF)-refractory metastatic renal cell carcinoma: clinical characteristics, risk factors, and subsequent therapy. | Annals of oncology : official journal of the European Society for Medical Oncology 20120601 |
| Sorafenib targets BCR kinases and blocks migratory and microenvironmental survival signals in CLL cells. | Leukemia 20120601 |
| Conventional transarterial chemoembolisation in combination with sorafenib for patients with hepatocellular carcinoma: a pilot study. | European radiology 20120601 |
| Complete response after sequential sunitinib-sorafenib treatment in a patient with renal cell carcinoma: a case report. | Clinical genitourinary cancer 20120601 |
| Blockade of ataxia telangiectasia mutated sensitizes hepatoma cell lines to sorafenib by interfering with Akt signaling. | Cancer letters 20120601 |
| Is there a role for targeted therapies in the collecting ducts of Bellini carcinoma? Efficacy data from a retrospective analysis of 7 cases. | Clinical and experimental nephrology 20120601 |
| Phase II study of concurrent transarterial chemoembolization and sorafenib in patients with unresectable hepatocellular carcinoma. | Journal of hepatology 20120601 |
| Survival of patients with hepatocellular carcinoma treated by transarterial chemoembolisation (TACE) using Drug Eluting Beads. Implications for clinical practice and trial design. | Journal of hepatology 20120601 |
| Combination therapy for hepatocellular carcinoma: additive preclinical efficacy of the HDAC inhibitor panobinostat with sorafenib. | Journal of hepatology 20120601 |
| Combination of Temsirolimus and tyrosine kinase inhibitors in renal carcinoma and endothelial cell lines. | Journal of cancer research and clinical oncology 20120601 |
| Sorafenib in combination with ionizing radiation has a greater anti-tumour activity in a breast cancer model. | Anti-cancer drugs 20120601 |
| Sorafenib decreases proliferation and induces apoptosis of prostate cancer cells by inhibition of the androgen receptor and Akt signaling pathways. | Endocrine-related cancer 20120601 |
| TACE with or without systemic therapy? | Journal of hepatology 20120601 |
| Management of hepatocellular carcinoma: beyond sorafenib. | Current oncology reports 20120601 |
| Cryotherapy is associated with improved clinical outcomes of Sorafenib therapy for advanced hepatocellular carcinoma. | Cell biochemistry and biophysics 20120601 |
| ITAM receptor-mediated generation of reactive oxygen species in human platelets occurs via Syk-dependent and Syk-independent pathways. | Journal of thrombosis and haemostasis : JTH 20120601 |
| Sorafenib in combination with transarterial chemoembolization and bronchial arterial chemoinfusion in the treatment of hepatocellular carcinoma with pulmonary metastasis. | Asia-Pacific journal of clinical oncology 20120601 |
| The efficacy of hepatic arterial infusion chemotherapy as an alternative to sorafenib in advanced hepatocellular carcinoma. | Asia-Pacific journal of clinical oncology 20120601 |
| SIRT1 is required for the effects of rapamycin on high glucose-inducing mesangial cells senescence. | Mechanisms of ageing and development 20120601 |
| Multiple cutaneous metastatic chordomas from the sacrum. | Journal of the American Academy of Dermatology 20120601 |
| Second-line therapy after VEGF targeted therapy in metastatic renal cancer: a law of diminishing returns. | Clinical genitourinary cancer 20120601 |
| Intermediate and advanced hepatocellular carcinoma treated with the antiangiogenic agent sorafenib. Evaluation with unenhanced and contrast-enhanced ultrasonography. | Medical ultrasonography 20120601 |
| [A case of advanced hepatocellular carcinoma with portal vein invasion successfully treated by sorafenib]. | Gan to kagaku ryoho. Cancer & chemotherapy 20120601 |
| Angiosarcoma of the scalp successfully treated with a single therapy of sorafenib. | Archives of dermatology 20120601 |
| The monoclonal antibody CH12 enhances the sorafenib-mediated growth inhibition of hepatocellular carcinoma xenografts expressing epidermal growth factor receptor variant III. | Neoplasia (New York, N.Y.) 20120601 |
| [Clinic predictors of efficacy and adverse events of sorafenib therapy for advanced hepatocellular carcinoma patients]. | Zhonghua wai ke za zhi [Chinese journal of surgery] 20120601 |
| [Simultaneous determination of flonicamid and its metabolites in cucumbers and apples by liquid chromatography-tandem mass spectrometry]. | Se pu = Chinese journal of chromatography 20120601 |
| Sorafenib treatment of FLT3-ITD(+) acute myeloid leukemia: favorable initial outcome and mechanisms of subsequent nonresponsiveness associated with the emergence of a D835 mutation. | Blood 20120531 |
| Distinct requirement for an intact dimer interface in wild-type, V600E and kinase-dead B-Raf signalling. | The EMBO journal 20120530 |
| Active site hydrophobic residues impact hydrogen tunneling differently in a thermophilic alcohol dehydrogenase at optimal versus nonoptimal temperatures. | Biochemistry 20120522 |
| Accelerated radiotherapy with carbogen and nicotinamide for laryngeal cancer: results of a phase III randomized trial. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120520 |
| Effects of the combined administration of propranolol plus sorafenib on portal hypertension in cirrhotic rats. | American journal of physiology. Gastrointestinal and liver physiology 20120515 |
| Atomic-resolution structures of horse liver alcohol dehydrogenase with NAD(+) and fluoroalcohols define strained Michaelis complexes. | Biochemistry 20120515 |
| [Efficacy and safety of sorafenib in the prevention and treatment of hepatocellular carcinoma recurrences after liver transplantation]. | Zhonghua yi xue za zhi 20120515 |
| Novel molecular targeted therapies for refractory thyroid cancer. | Head & neck 20120501 |
| Clinical efficacy and prognostic factors for overall survival in Japanese patients with metastatic renal cell cancer treated with sunitinib. | BJU international 20120501 |
| Patterns of care, prognosis, and survival in patients with metastatic gastrointestinal stromal tumors (GIST) refractory to first-line imatinib and second-line sunitinib. | Annals of surgical oncology 20120501 |
| Protective function of nicotinamide against ketamine-induced apoptotic neurodegeneration in the infant rat brain. | Journal of molecular neuroscience : MN 20120501 |
| Phase I trial of sorafenib in combination with 5-fluorouracil/leucovorin in advanced solid tumors. | Journal of clinical pharmacology 20120501 |
| Relationship between baseline hepatic status and outcome, and effect of sorafenib on liver function: SHARP trial subanalyses. | Journal of hepatology 20120501 |
| Sorafenib for recurrence of hepatocellular carcinoma after liver transplantation. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20120501 |
| Anti-Trypanosoma cruzi activity of nicotinamide. | Acta tropica 20120501 |
| Oral nicotinamide reduces actinic keratoses in phase II double-blinded randomized controlled trials. | The Journal of investigative dermatology 20120501 |
| MCL1 down-regulation plays a critical role in mediating the higher anti-leukaemic activity of the multi-kinase inhibitor Sorafenib with respect to Dasatinib. | British journal of haematology 20120501 |
| Molecular targeted therapies for cancer: sorafenib mono-therapy and its combination with other therapies (review). | Oncology reports 20120501 |
| Targeted therapeutic strategies for the management of renal cell carcinoma. | Current opinion in oncology 20120501 |
| Incidence of thyroid hormone therapy in patients treated with sunitinib or sorafenib: a cohort study. | European journal of cancer (Oxford, England : 1990) 20120501 |
| Sorafenib and HDAC inhibitors synergize to kill CNS tumor cells. | Cancer biology & therapy 20120501 |
| Sorafenib inhibits endogenous and IL-6/S1P induced JAK2-STAT3 signaling in human neuroblastoma, associated with growth suppression and apoptosis. | Cancer biology & therapy 20120501 |
| Sorafenib in combination with capecitabine: an oral regimen for patients with HER2-negative locally advanced or metastatic breast cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120501 |
| Potential impact of sorafenib on the survival benefit of liver transplantation for hepatocellular carcinoma. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20120501 |
| Pancreatic metastasis arising from a BRAF(V600E)-positive papillary thyroid cancer: the role of endoscopic ultrasound-guided biopsy and response to sorafenib therapy. | Thyroid : official journal of the American Thyroid Association 20120501 |
| Advanced-stage hepatocellular carcinoma: transarterial chemoembolization versus sorafenib. | Radiology 20120501 |
| Captopril attenuates hypertension and renal injury induced by the vascular endothelial growth factor inhibitor sorafenib. | Clinical and experimental pharmacology & physiology 20120501 |
| Sorafenib for treatment of hepatocellular carcinoma: a systematic review. | Digestive diseases and sciences 20120501 |
| Design, synthesis and biological activities of thiourea containing sorafenib analogs as antitumor agents. | Bioorganic & medicinal chemistry 20120501 |
| Sorafenib in liver cancer. | Expert opinion on pharmacotherapy 20120501 |
| Role of Vitamins B-3 and C in the fashioning of granules in UASB reactor sludge. | Applied biochemistry and biotechnology 20120501 |
| [First-line therapy of advanced or metastasized renal cell cancer: open randomized phase III sequence study to examine the effectiveness and tolerance of sorafenib followed by pazopanib versus pazopanib followed by sorafenib in the first-line treatment of patients with advanced or metastasized renal cell cancer (SWITCH-2 - AN 33/11)]. | Der Urologe. Ausg. A 20120501 |
| Painful leg mass. | The Journal of family practice 20120501 |
| Streptozotocin-nicotinamide-induced diabetes in the rat. Characteristics of the experimental model. | Experimental biology and medicine (Maywood, N.J.) 20120501 |
| Appropriate management of cutaneous adverse events maximizes compliance with sorafenib treatment: a single-center experience. | Future oncology (London, England) 20120501 |
| Immunotherapies in diabetes mellitus type 1. | The Medical clinics of North America 20120501 |
| Immunostimulant, cerebroprotective & nootropic activities of Andrographis paniculata leaves extract in normal & type 2 diabetic rats. | The Indian journal of medical research 20120501 |
| A reversible early oxidized redox state that precedes macromolecular ROS damage in aging nontransgenic and 3xTg-AD mouse neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20120425 |
| A flavoprotein monooxygenase that catalyses a Baeyer-Villiger reaction and thioether oxidation using NADH as the nicotinamide cofactor. | Chembiochem : a European journal of chemical biology 20120416 |
| Monitoring ibuprofen-nicotinamide cocrystal formation during solvent free continuous cocrystallization (SFCC) using near infrared spectroscopy as a PAT tool. | International journal of pharmaceutics 20120415 |
| Resampling phase III data to assess phase II trial designs and endpoints. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120415 |
| Plasma biomarkers as predictors of outcome in patients with advanced hepatocellular carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120415 |
| Dynamic reprogramming of the kinome in response to targeted MEK inhibition in triple-negative breast cancer. | Cell 20120413 |
| Design and synthesis of novel lactate dehydrogenase A inhibitors by fragment-based lead generation. | Journal of medicinal chemistry 20120412 |
| [Relationship between sorafenib-associated hand-food skin reaction and efficacy in treatment of advanced hepatocellular carcinoma]. | Zhonghua yi xue za zhi 20120403 |
| The plasma and cerebrospinal fluid pharmacokinetics of sorafenib after intravenous administration in non-human primates. | Investigational new drugs 20120401 |
| Sorafenib sensitizes hepatocellular carcinoma cells to physiological apoptotic stimuli. | Journal of cellular physiology 20120401 |
| Strategies for assessing and managing the adverse events of sorafenib and other targeted therapies in the treatment of renal cell and hepatocellular carcinoma: recommendations from a European nursing task group. | European journal of oncology nursing : the official journal of European Oncology Nursing Society 20120401 |
| Sorafenib and cisplatin/doxorubicin (PLADO) in pediatric hepatocellular carcinoma. | Pediatric blood & cancer 20120401 |
| Photochemical interaction of ascorbic acid with riboflavin, nicotinamide and alpha-tocopherol in cream formulations. | International journal of cosmetic science 20120401 |
| Molecular characterization of boscalid- and penthiopyrad-resistant isolates of Didymella bryoniae and assessment of their sensitivity to fluopyram. | Pest management science 20120401 |
| Treatment effects of the multikinase inhibitor sorafenib on hepatoblastoma cell lines and xenografts in NMRI-Foxn1 nu mice. | Liver international : official journal of the International Association for the Study of the Liver 20120401 |
| Iron facilitator LS081 reduces hypoxia-inducible factor-1α protein and functions as anticancer agent in hepatocellular carcinoma. | Cancer science 20120401 |
| Nicotinamide, a SIRT1 inhibitor, inhibits differentiation and facilitates expansion of hematopoietic progenitor cells with enhanced bone marrow homing and engraftment. | Experimental hematology 20120401 |
| Efficacy and safety of vascular endothelial growth factor receptor tyrosine kinase inhibitors in patients with metastatic renal cell carcinoma and poor risk features. | Journal of cancer research and clinical oncology 20120401 |
| Sorafenib in metastatic thyroid cancer. | Endocrine-related cancer 20120401 |
| Sorafenib is an inhibitor of UGT1A1 but is metabolized by UGT1A9: implications of genetic variants on pharmacokinetics and hyperbilirubinemia. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120401 |
| Bortezomib induces apoptosis and growth suppression in human medulloblastoma cells, associated with inhibition of AKT and NF-ĸB signaling, and synergizes with an ERK inhibitor. | Cancer biology & therapy 20120401 |
| Nitric oxide production and endothelium-dependent vasorelaxation ameliorated by N1-methylnicotinamide in human blood vessels. | Hypertension (Dallas, Tex. : 1979) 20120401 |
| Intracranial metastasis from pediatric GI stromal tumor. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120401 |
| Mechanical stress-activated immune response genes via Sirtuin 1 expression in human periodontal ligament cells. | Clinical and experimental immunology 20120401 |
| Sorafenib in melanoma. | Expert opinion on investigational drugs 20120401 |
| The effect of hydro alcoholic extract of Juglans regia leaves in streptozotocin-nicotinamide induced diabetic rats. | Pakistan journal of pharmaceutical sciences 20120401 |
| Improved physicochemical characteristics of artemisinin-nicotinamide solid dispersions by solvent evaporation and freeze dried methods. | Pakistan journal of pharmaceutical sciences 20120401 |
| Molecular targeted therapy in acute myeloid leukemia. | Hematology (Amsterdam, Netherlands) 20120401 |
| Carbon nanostructures interacting with vitamins A, B3 and C: ab initio simulations. | Journal of biomedical nanotechnology 20120401 |
| Leishmania infantum nicotinamidase is required for late-stage development in its natural sand fly vector, Phlebotomus perniciosus. | International journal for parasitology 20120401 |
| Hepatocellular carcinoma. | Lancet (London, England) 20120331 |
| Synthesis, photophysical, photochemical, and computational studies of coumarin-labeled nicotinamide derivatives. | The Journal of organic chemistry 20120316 |
| Indian health groups welcome country's first compulsory licence. | BMJ (Clinical research ed.) 20120316 |
| Meta-analysis of randomized controlled trials for the incidence and risk of treatment-related mortality in patients with cancer treated with vascular endothelial growth factor tyrosine kinase inhibitors. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120310 |
| Insight into the cooperation of P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) at the blood-brain barrier: a case study examining sorafenib efflux clearance. | Molecular pharmaceutics 20120305 |
| Sorafenib-induced mitochondrial complex I inactivation and cell death in human neuroblastoma cells. | Journal of proteome research 20120302 |
| A rare case of metastatic pancreatic hepatoid carcinoma treated with sorafenib. | Journal of gastrointestinal cancer 20120301 |
| Nicotinamide inhibits the early stage of carcinogen-induced hepatocarcinogenesis in mice and suppresses human hepatocellular carcinoma cell growth. | Journal of cellular physiology 20120301 |
| Polymeric nanoparticle-encapsulated hedgehog pathway inhibitor HPI-1 (NanoHHI) inhibits systemic metastases in an orthotopic model of human hepatocellular carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120301 |
| Are there opportunities for chemotherapy in the treatment of hepatocellular cancer? | Journal of hepatology 20120301 |
| Effects of dietary glutamine on inflammatory mediator gene expressions in rats with streptozotocin-induced diabetes. | Nutrition (Burbank, Los Angeles County, Calif.) 20120301 |
| Improving the chemical stability of amorphous solid dispersion with cocrystal technique by hot melt extrusion. | Pharmaceutical research 20120301 |
| Phase II trial of sorafenib in combination with 5-fluorouracil infusion in advanced hepatocellular carcinoma. | Cancer chemotherapy and pharmacology 20120301 |
| Nicotinamide attenuates the decrease of astrocytic phosphoprotein PEA-15 in focal cerebral ischemic injury. | The Journal of veterinary medical science 20120301 |
| [Renal tolerance of targeted therapies]. | Bulletin du cancer 20120301 |
| Therapeutic benefits of the group B3 vitamin nicotinamide in mice with lethal endotoxemia and polymicrobial sepsis. | Pharmacological research 20120301 |
| Phase I trial of everolimus plus sorafenib for patients with advanced renal cell cancer. | Clinical genitourinary cancer 20120301 |
| Nicotinamide dependence of uropathogenic Escherichia coli UTI89 and application of nadB as a neutral insertion site. | Microbiology (Reading, England) 20120301 |
| Early evaluation of transcatheter arterial chemoembolization-refractory hepatocellular carcinoma. | Journal of gastroenterology 20120301 |
| Phase II study of weekly paclitaxel and sorafenib as second/third-line therapy in patients with adrenocortical carcinoma. | European journal of endocrinology 20120301 |
| Sorafenib, a multikinase inhibitor, is effective in vitro against non-Hodgkin lymphoma and synergizes with the mTOR inhibitor rapamycin. | American journal of hematology 20120301 |
| Objective response to sorafenib in advanced clear-cell sarcoma. | Annals of oncology : official journal of the European Society for Medical Oncology 20120301 |
| Phase I trial to investigate the safety, pharmacokinetics and efficacy of sorafenib combined with docetaxel in patients with advanced refractory solid tumours. | European journal of cancer (Oxford, England : 1990) 20120301 |
| Clinical activity of sorafenib in patients with advanced gastrointestinal stromal tumor bearing PDGFRA exon 18 mutation: a case series. | Annals of oncology : official journal of the European Society for Medical Oncology 20120301 |
| Revealing multi-binding sites for taspine to VEGFR-2 by cell membrane chromatography zonal elution. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120301 |
| Transarterial chemoembolization plus sorafenib: a sequential therapeutic scheme for HCV-related intermediate-stage hepatocellular carcinoma: a randomized clinical trial. | The oncologist 20120301 |
| Using NF-κB as a molecular target for theranostics in radiation oncology research. | Expert review of molecular diagnostics 20120301 |
| Male skin and ingredients relevant to male skin care. | The British journal of dermatology 20120301 |
| Effects of employing a ¹⁰B-carrier and manipulating intratumour hypoxia on local tumour response and lung metastatic potential in boron neutron capture therapy. | The British journal of radiology 20120301 |
| [Nicorandil and ulceration: a physiopathological hypothesis]. | Annales de dermatologie et de venereologie 20120301 |
| [Possibilities for inhibiting tumor-induced angiogenesis: results with multi-target tyrosine kinase inhibitors]. | Magyar onkologia 20120301 |
| Advanced HCC: emerging molecular therapies. | Minerva gastroenterologica e dietologica 20120301 |
| Nicotinamide postpones stroke in stroke-prone spontaneously hypertensive rats. | CNS neuroscience & therapeutics 20120301 |
| LMW-E/CDK2 deregulates acinar morphogenesis, induces tumorigenesis, and associates with the activated b-Raf-ERK1/2-mTOR pathway in breast cancer patients. | PLoS genetics 20120301 |
| [Protective effect of nicotinamide in a mouse Parkinson's disease model]. | Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20120301 |
| [Hydrolytic property and solution stability of NAMI derivative containing nicotinamide]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120301 |
| Developments in metastatic pancreatic cancer: is gemcitabine still the standard? | World journal of gastroenterology 20120227 |
| Sorafenib down-regulates c-IAP expression post-transcriptionally in hepatic carcinoma cells to suppress apoptosis. | Biochemical and biophysical research communications 20120217 |
| Phase I study of the combination of sorafenib and temsirolimus in patients with metastatic melanoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120215 |
| Randomized phase II trial of sorafenib with temsirolimus or tipifarnib in untreated metastatic melanoma (S0438). | Clinical cancer research : an official journal of the American Association for Cancer Research 20120215 |
| Treatment of patients with advanced neurofibromatosis type 2 with novel molecularly targeted therapies: from bench to bedside. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120210 |
| Complete remission with tyrosine kinase inhibitors in renal cell carcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120210 |
| Structural basis of selective inhibition of human tankyrases. | Journal of medicinal chemistry 20120209 |
| Gemcitabine plus sorafenib in patients with advanced pancreatic cancer: a phase II trial of the University of Chicago Phase II Consortium. | Investigational new drugs 20120201 |
| Phase I dose-finding study of sorafenib in combination with capecitabine and cisplatin as a first-line treatment in patients with advanced gastric cancer. | Investigational new drugs 20120201 |
| Combining functional imaging and interstitial pressure measurements to evaluate two anti-angiogenic treatments. | Investigational new drugs 20120201 |
| Acute toxicity profile and compliance to accelerated radiotherapy plus carbogen and nicotinamide for clinical stage T2-4 laryngeal cancer: results of a phase III randomized trial. | International journal of radiation oncology, biology, physics 20120201 |
| Preclincial testing of sorafenib and RAD001 in the Nf(flox/flox) ;DhhCre mouse model of plexiform neurofibroma using magnetic resonance imaging. | Pediatric blood & cancer 20120201 |
| Anti-tumor activity of motesanib in a medullary thyroid cancer model. | Journal of endocrinological investigation 20120201 |
| A phase II trial of sorafenib in relapsed and unresectable high-grade osteosarcoma after failure of standard multimodal therapy: an Italian Sarcoma Group study. | Annals of oncology : official journal of the European Society for Medical Oncology 20120201 |
| Sunitinib followed by sorafenib or vice versa for metastatic renal cell carcinoma--data from the Czech registry. | Annals of oncology : official journal of the European Society for Medical Oncology 20120201 |
| Bufalin enhances the anti-proliferative effect of sorafenib on human hepatocellular carcinoma cells through downregulation of ERK. | Molecular biology reports 20120201 |
| [KIT and KIT: from biology to clinical use]. | Bulletin du cancer 20120201 |
| Phase IB study of sorafenib in combination with gemcitabine and cisplatin in patients with refractory solid tumors. | Cancer chemotherapy and pharmacology 20120201 |
| Characterization of human nicotinate phosphoribosyltransferase: Kinetic studies, structure prediction and functional analysis by site-directed mutagenesis. | Biochimie 20120201 |
| Phase 2 Southwest Oncology Group-directed intergroup trial (S0505) of sorafenib in advanced soft tissue sarcomas. | Cancer 20120201 |
| Excess nicotinamide inhibits methylation-mediated degradation of catecholamines in normotensives and hypertensives. | Hypertension research : official journal of the Japanese Society of Hypertension 20120201 |
| Nicotinamide inhibits nuclear factor-kappa B translocation after transient focal cerebral ischemia. | Critical care medicine 20120201 |
| [Role of mitogen-activated protein kinase (MAPK) in the sporadic renal cell carcinoma]. | Actas urologicas espanolas 20120201 |
| Anti-angiogenic therapy: concept to clinic. | Microcirculation (New York, N.Y. : 1994) 20120201 |
| Sorafenib and Mek inhibition is synergistic in medullary thyroid carcinoma in vitro. | Endocrine-related cancer 20120201 |
| The role of autoantibodies to zinc transporter 8 in prediction of type 1 diabetes in relatives: lessons from the European Nicotinamide Diabetes Intervention Trial (ENDIT) cohort. | The Journal of clinical endocrinology and metabolism 20120201 |
| Dovitinib induces apoptosis and overcomes sorafenib resistance in hepatocellular carcinoma through SHP-1-mediated inhibition of STAT3. | Molecular cancer therapeutics 20120201 |
| Sorafenib sensitizes (-)-gossypol-induced growth suppression in androgen-independent prostate cancer cells via Mcl-1 inhibition and Bak activation. | Molecular cancer therapeutics 20120201 |
| Immunology in the clinic review series; focus on cancer: tumour-associated macrophages: undisputed stars of the inflammatory tumour microenvironment. | Clinical and experimental immunology 20120201 |
| [Hepatocellular carcinoma: what's new?]. | Deutsche medizinische Wochenschrift (1946) 20120201 |
| Sorafenib for the treatment of renal cancer. | Expert opinion on pharmacotherapy 20120201 |
| Sorafenib sensitizes human colorectal carcinoma to radiation via suppression of NF-κB expression in vitro and in vivo. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20120201 |
| Perfusion MRI for monitoring the effect of sorafenib on experimental prostate carcinoma: a validation study. | AJR. American journal of roentgenology 20120201 |
| Sorafenib for patients with advanced angiosarcoma: a phase II Trial from the French Sarcoma Group (GSF/GETO). | The oncologist 20120201 |
| Phase II studies in soft tissue sarcoma: time for reappraisal. | The oncologist 20120201 |
| Inflammation-based prognostic score for hepatocellular carcinoma patients on sorafenib treatment. | Anticancer research 20120201 |
| Metastatic renal cell carcinoma treated sequentially with multiple VEGF receptor-targeted inhibitors--a case report. | Anticancer research 20120201 |
| An approach to the chemotaxonomic differentiation of two European dog's mercury species: Mercurialis annua L. and M. perennis L. | Chemistry & biodiversity 20120201 |
| Difference in glucose intolerance between C57BL/6J and ICR strain mice with streptozotocin/nicotinamide-induced diabetes. | Biomedical research (Tokyo, Japan) 20120201 |
| [Sorafenib and octreotide combination therapy can inhibit proliferation of and induce apoptosis in human hepatoma cells]. | Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20120201 |
| [Immune system disorders and their correction in critically ill patients with toxic and hypoxic encephalopathy]. | Georgian medical news 20120201 |
| [Use of cytoflavin into the complex intensive therapy of acute cerebral insufficiency caused by poisoning]. | Georgian medical news 20120201 |
| Differentiation of human labia minora dermis-derived fibroblasts into insulin-producing cells. | Experimental & molecular medicine 20120131 |
| New sorafenib derivatives: synthesis, antiproliferative activity against tumour cell lines and antimetabolic evaluation. | Molecules (Basel, Switzerland) 20120123 |
| RAS mutations are associated with the development of cutaneous squamous cell tumors in patients treated with RAF inhibitors. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120120 |
| Targeted therapies for renal cell carcinoma: review of adverse event management strategies. | Journal of the National Cancer Institute 20120118 |
| Pericyte depletion results in hypoxia-associated epithelial-to-mesenchymal transition and metastasis mediated by met signaling pathway. | Cancer cell 20120117 |
| NAD(P)H oxidase-dependent intracellular and extracellular O2•- production in coronary arterial myocytes from CD38 knockout mice. | Free radical biology & medicine 20120115 |
| [Endocrinology]. | Revue medicale suisse 20120111 |
| Structural and kinetic isotope effect studies of nicotinamidase (Pnc1) from Saccharomyces cerevisiae. | Biochemistry 20120110 |
| Ameliorative effect of diosmin, a citrus flavonoid against streptozotocin-nicotinamide generated oxidative stress induced diabetic rats. | Chemico-biological interactions 20120105 |
| Histone deacetylase inhibitors (HDACIs). Structure--activity relationships: history and new QSAR perspectives. | Medicinal research reviews 20120101 |
| An update on targeted therapy in metastatic renal cell carcinoma. | Urologic oncology 20120101 |
| Functional analysis of microRNAs in human hepatocellular cancer stem cells. | Journal of cellular and molecular medicine 20120101 |
| A cytokine and angiogenic factor (CAF) analysis in plasma for selection of sorafenib therapy in patients with metastatic renal cell carcinoma. | Annals of oncology : official journal of the European Society for Medical Oncology 20120101 |
| The transient catalytically competent coenzyme allocation into the active site of Anabaena ferredoxin NADP+ -reductase. | European biophysics journal : EBJ 20120101 |
| A drug interaction study evaluating the pharmacokinetics and toxicity of sorafenib in combination with capecitabine. | Cancer chemotherapy and pharmacology 20120101 |
| Comparison of tumor response by Response Evaluation Criteria in Solid Tumors (RECIST) and modified RECIST in patients treated with sorafenib for hepatocellular carcinoma. | Cancer 20120101 |
| Transient partial response to sorafenib treatment in an adolescent patient with MEN2B syndrome and end-stage medullary thyroid carcinoma. | Pediatric blood & cancer 20120101 |
| Is advanced hepatocellular carcinoma amenable of cure by liver transplantation with sorafenib as a neoadjuvant approach plus m-TOR inhibitors monotherapy? | Journal of surgical oncology 20120101 |
| Limited clinical activity of nilotinib and sorafenib in FIP1L1-PDGFRA positive chronic eosinophilic leukemia with imatinib-resistant T674I mutation. | Leukemia 20120101 |
| [Long-standing differentiated thyroid carcinoma]. | Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion 20120101 |
| Characterization of kinase inhibitors using different phosphorylation states of colony stimulating factor-1 receptor tyrosine kinase. | Journal of biochemistry 20120101 |
| Nicotinamide prevents the down-regulation of MEK/ERK/p90RSK signaling cascade in brain ischemic injury. | The Journal of veterinary medical science 20120101 |
| Efficacy and safety of sorafenib in combination with mammalian target of rapamycin inhibitors for recurrent hepatocellular carcinoma after liver transplantation. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20120101 |
| Dynamic contrast-enhanced computed tomography imaging biomarkers correlated with immunohistochemistry for monitoring the effects of sorafenib on experimental prostate carcinomas. | Investigative radiology 20120101 |
| Sorafenib-induced apoptosis of chronic lymphocytic leukemia cells is associated with downregulation of RAF and myeloid cell leukemia sequence 1 (Mcl-1). | Molecular medicine (Cambridge, Mass.) 20120101 |
| The successful remission induction by sorafenib and long-term complete remission in a FLT3-ITD-positive patient with a refractory acute erythroid leukemia and abnormal cytogenetics. | Leukemia research 20120101 |
| The effects of sorafenib on the portal hypertensive syndrome in patients with liver cirrhosis and hepatocellular carcinoma--a pilot study. | Alimentary pharmacology & therapeutics 20120101 |
| Pre-B-cell colony-enhancing factor exerts a neuronal protection through its enzymatic activity and the reduction of mitochondrial dysfunction in in vitro ischemic models. | Journal of neurochemistry 20120101 |
| Skin tumors induced by sorafenib; paradoxic RAS-RAF pathway activation and oncogenic mutations of HRAS, TP53, and TGFBR1. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120101 |
| Downsizing a thrombus of advanced renal cell carcinoma in a presurgical setting with sorafenib. | Urologia internationalis 20120101 |
| Paclitaxel in combination with sorafenib and bevacizumab in patients with locally advanced or metastatic solid tumors. | International journal of clinical pharmacology and therapeutics 20120101 |
| Two randomized, controlled, comparative studies of the stratum corneum integrity benefits of two cosmetic niacinamide/glycerin body moisturizers vs. conventional body moisturizers. | Journal of drugs in dermatology : JDD 20120101 |
| Phase II escalation study of sorafenib in patients with metastatic renal cell carcinoma who have been previously treated with anti-angiogenic treatment. | BJU international 20120101 |
| Sorafenib (BAY 43-9006) in hepatocellular carcinoma patients: from discovery to clinical development. | Current medicinal chemistry 20120101 |
| The urinary excretory ratio of nicotinamide catabolites was associated with the conversion ratio of tryptophan to nicotinamide in growing rats fed a niacin-free 20% casein diet. | Bioscience, biotechnology, and biochemistry 20120101 |
| Targeting of distinct signaling cascades and cancer-associated fibroblasts define the efficacy of Sorafenib against prostate cancer cells. | Cell death & disease 20120101 |
| SirT1 confers hypoxia-induced radioresistance via the modulation of c-Myc stabilization on hepatoma cells. | Journal of radiation research 20120101 |
| Sorafenib for hepatocellular carcinoma patients beyond Milan criteria after orthotopic liver transplantation: a case control study. | World journal of surgical oncology 20120101 |
| Effects of N1-methylnicotinamide on oxidative and glycooxidative stress markers in rats with streptozotocin-induced diabetes mellitus. | Redox report : communications in free radical research 20120101 |
| Effects of sorafenib on intra-tumoral interstitial fluid pressure and circulating biomarkers in patients with refractory sarcomas (NCI protocol 6948). | PloS one 20120101 |
| Sorafenib dose escalation in the treatment of advanced hepatocellular carcinoma. | Oncology 20120101 |
| Niacinamide mitigated the acute lung injury induced by phorbol myristate acetate in isolated rat's lungs. | Journal of biomedical science 20120101 |
| Developmental changes of aldehyde oxidase activity and protein expression in human liver cytosol. | Drug metabolism and pharmacokinetics 20120101 |
| Vitamin K1 enhances sorafenib-induced growth inhibition and apoptosis of human malignant glioma cells by blocking the Raf/MEK/ERK pathway. | World journal of surgical oncology 20120101 |
| Hematopoietic prostaglandin D synthase inhibitors. | Progress in medicinal chemistry 20120101 |
| Mutagenesis and functional studies with succinate dehydrogenase inhibitors in the wheat pathogen Mycosphaerella graminicola. | PloS one 20120101 |
| Resveratrol mediated modulation of Sirt-1/Runx2 promotes osteogenic differentiation of mesenchymal stem cells: potential role of Runx2 deacetylation. | PloS one 20120101 |
| [Metabolic immunocorrection treatment of experimental widespread purulent peritonitis]. | Eksperimental'naia i klinicheskaia farmakologiia 20120101 |
| Early assessment by FDG-PET/CT of patients with advanced renal cell carcinoma treated with tyrosine kinase inhibitors is predictive of disease course. | BMC cancer 20120101 |
| [Studies by means of 1H NMR spectroscopy of complex formation of aromatic biologically active compounds with antibiotic topotecan]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20120101 |
| [Nicotinamide influence on pancreatic cells viability]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20120101 |
| [The efficacy of cytoflavin used for the correction of psychoemotional and neuroimmune disturbances in the patients presenting with eczema]. | Klinicheskaia meditsina 20120101 |
| Sorafenib prevents escape from host immunity in liver cirrhosis patients with advanced hepatocellular carcinoma. | Clinical & developmental immunology 20120101 |
| Sarcopenia predicts early dose-limiting toxicities and pharmacokinetics of sorafenib in patients with hepatocellular carcinoma. | PloS one 20120101 |
| [Neuroimmune aspects of the pathogenesis and nitric oxide negative effects modifying the pathogenetic treatment of tick-borne infections]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20120101 |
| A pooled analysis of sequential therapies with sorafenib and sunitinib in metastatic renal cell carcinoma. | Oncology 20120101 |
| Clinical response after sorafenib for hepatocellular carcinoma in elderly patients: a report of two cases. | Tumori 20120101 |
| The different induction mechanisms of growth arrest DNA damage inducible gene 45 β in human hepatoma cell lines. | Chemotherapy 20120101 |
| [Correction of protein-lipid composition in liver mitochondria during experimental widespread purulent peritonitis]. | Eksperimental'naia i klinicheskaia farmakologiia 20120101 |
| Development of coronary artery stenosis in a patient with metastatic renal cell carcinoma treated with sorafenib. | BMC cancer 20120101 |
| Celecoxib synergizes human pancreatic ductal adenocarcinoma cells to sorafenib-induced growth inhibition. | Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20120101 |
| [Correction of mnestico-intellectual disturbances in the somatogenic phase of acute poisoning with a mixture of psychotropic drugs]. | Klinicheskaia meditsina 20120101 |
| Nicotinamide pretreatment protects cardiomyocytes against hypoxia-induced cell death by improving mitochondrial stress. | Pharmacology 20120101 |
| The efficacy of TACE combined sorafenib in advanced stages hepatocellullar carcinoma. | BMC cancer 20120101 |
| Molecular dynamics simulations suggest ligand's binding to nicotinamidase/pyrazinamidase. | PloS one 20120101 |
| Sorafenib inhibits TPA-induced MMP-9 and VEGF expression via suppression of ERK/NF-κB pathway in hepatocellular carcinoma cells. | In vivo (Athens, Greece) 20120101 |
| The inhibition of the pemetrexed-activated MAPK pathway via sorafenib is involved in the synergistic mechanism of sorafenib subsequent potentiation of pemetrexed cytotoxicity in EGFR TKI-resistant cell lines. | Clinical laboratory 20120101 |
| Preparation, in vitro release, and pharmacokinetics in rabbits of lyophilized injection of sorafenib solid lipid nanoparticles. | International journal of nanomedicine 20120101 |
| Current status and perspectives of targeted therapy in well-differentiated neuroendocrine tumors. | Oncology 20120101 |
| [The immune activity of cytoflavine in the treatment of the diffuse septic peritonitis]. | Khirurgiia 20120101 |
| BAY61-3606 affects the viability of colon cancer cells in a genotype-directed manner. | PloS one 20120101 |
| Comparison of the effects of two kinase inhibitors, sorafenib and dasatinib, on chronic lymphocytic leukemia cells. | Onkologie 20120101 |
| Novel piperazinyl derivatives with anti-hyperalgesic, anti-allodynic and anti-inflammatory activities useful for the treatment of Neuropathic Pain. | Anti-inflammatory & anti-allergy agents in medicinal chemistry 20120101 |
| Metabolic fate of 14C-labelled nicotinamide and adenine in germinating propagules of the mangrove Bruguiera gymnorrhiza. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20120101 |
| Evaluation of the mRECIST and α-fetoprotein ratio for stratification of the prognosis of advanced-hepatocellular-carcinoma patients treated with sorafenib. | Oncology 20120101 |
| Experimentally induced rodent models of type 2 diabetes. | Methods in molecular biology (Clifton, N.J.) 20120101 |
| Decreased skin-mediated detoxification contributes to oxidative stress and insulin resistance. | Experimental diabetes research 20120101 |
| [The application of combined physiotherapeutic methods for the complex treatment of patients with dyscirculatory encephalopathy]. | Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury 20120101 |
| Early sorafenib-induced toxicity is associated with drug exposure and UGTIA9 genetic polymorphism in patients with solid tumors: a preliminary study. | PloS one 20120101 |
| Efficient differentiation of mouse embryonic stem cells into insulin-producing cells. | Experimental diabetes research 20120101 |
| [Hepatocellular carcinoma - long-term treatable disease]. | Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti 20120101 |
| Hypothyroidism during treatment with tyrosine kinase inhibitors. | Endokrynologia Polska 20120101 |
| State of the art of the therapeutic perspective of sorafenib against hematological malignancies. | Current medicinal chemistry 20120101 |
| Clinicopathological characteristics of hepatocellular carcinoma in Turkey. | Asian Pacific journal of cancer prevention : APJCP 20120101 |
| 2,3-dihydro-1H-cyclopenta[b]quinoline derivatives as acetylcholinesterase inhibitors-synthesis, radiolabeling and biodistribution. | International journal of molecular sciences 20120101 |
| Affinity purification of protein kinases that adopt a specific inactive conformation. | Methods in molecular biology (Clifton, N.J.) 20120101 |
| Differential effects of arsenic trioxide on chemosensitization in human hepatic tumor and stellate cell lines. | BMC cancer 20120101 |
| Antidiabetic effects of SGLT2-selective inhibitor ipragliflozin in streptozotocin-nicotinamide-induced mildly diabetic mice. | Journal of pharmacological sciences 20120101 |
| Meliacinolin: a potent α-glucosidase and α-amylase inhibitor isolated from Azadirachta indica leaves and in vivo antidiabetic property in streptozotocin-nicotinamide-induced type 2 diabetes in mice. | Biological & pharmaceutical bulletin 20120101 |
| Polymorphisms to predict outcome to the tyrosine kinase inhibitors gefitinib, erlotinib, sorafenib and sunitinib. | Current topics in medicinal chemistry 20120101 |
| [Pharmacologic correction of hypoxia in patients with acute cerebral failure due to acute poisoning with carbon monoxide and combustion products]. | Meditsina truda i promyshlennaia ekologiia 20120101 |
| Sorafenib-induced tuberculosis reactivation. | Onkologie 20120101 |
| Sirt5 deacylation activities show differential sensitivities to nicotinamide inhibition. | PloS one 20120101 |
| [Multikinase inhibitor sorafenib and HDAC inhibitor suberoylanilide hydroxamic acid suppress confluent resistance of cancer cells to recombinant protein izTRAIL]. | Biofizika 20120101 |
| Sorafenib modulates the radio sensitivity of hepatocellular carcinoma cells in vitro in a schedule-dependent manner. | BMC cancer 20120101 |
| Effects of sorafenib on C-terminally truncated androgen receptor variants in human prostate cancer cells. | International journal of molecular sciences 20120101 |
| Resveratrol improves diabetic retinopathy possibly through oxidative stress - nuclear factor κB - apoptosis pathway. | Pharmacological reports : PR 20120101 |
| Creation of bioorthogonal redox systems depending on nicotinamide flucytosine dinucleotide. | Journal of the American Chemical Society 20111228 |
| Molecular dynamics simulation and free energy calculation studies of the binding mechanism of allosteric inhibitors with p38α MAP kinase. | Journal of chemical information and modeling 20111227 |
| Role of BRAF in thyroid oncogenesis. | Clinical cancer research : an official journal of the American Association for Cancer Research 20111215 |
| A novel preclinical strategy for identifying cardiotoxic kinase inhibitors and mechanisms of cardiotoxicity. | Circulation research 20111209 |
| Severe clinical toxicities are correlated with survival in patients with advanced renal cell carcinoma treated with sunitinib and sorafenib. | British journal of cancer 20111206 |
| Tilting the AXIS towards therapeutic limits in renal cancer. | Lancet (London, England) 20111203 |
| Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial. | Lancet (London, England) 20111203 |
| Combined anticancer effects of sphingosine kinase inhibitors and sorafenib. | Investigational new drugs 20111201 |
| Sustained response following sorafenib therapy in an older adult patient with advanced renal cancer on hemodialysis: a case report. | Medical oncology (Northwood, London, England) 20111201 |
| Long-term stable disease in metastatic renal cell carcinoma: sorafenib sequenced to sunitinib and everolimus: a case study. | Medical oncology (Northwood, London, England) 20111201 |
| Safe use of sorafenib in a patient undergoing salvage liver transplantation for recurrent hepatocellular carcinoma after hepatic resection. | Medical oncology (Northwood, London, England) 20111201 |
| Pharmacokinetic interaction involving sorafenib and the calcium-channel blocker felodipine in a patient with hepatocellular carcinoma. | Investigational new drugs 20111201 |
| Complete response after sorafenib therapy for hepatocellular carcinoma in an HIV-HBV co infected patient: Possible synergy with HAART ? A case report. | Medical oncology (Northwood, London, England) 20111201 |
| Impressive efficacy of sorafenib in a patient with an hepatocellular carcinoma and a portal vein thrombosis associated with a metastatic ENT cancer. | Medical oncology (Northwood, London, England) 20111201 |
| Hypothyroidism correlates with a better prognosis in metastatic renal cancer patients treated with sorafenib or sunitinib. | World journal of urology 20111201 |
| Safety and pharmacokinetics of sorafenib combined with capecitabine in patients with advanced solid tumors: results of a phase 1 trial. | Journal of clinical pharmacology 20111201 |
| The anti-inflammatory and antioxidative effects of nicotinamide, a vitamin B(3) derivative, are elicited by FoxO3 in human gestational tissues: implications for preterm birth. | The Journal of nutritional biochemistry 20111201 |
| Antidiabetic activity of standardized extract of Quassia amara in nicotinamide-streptozotocin-induced diabetic rats. | Phytotherapy research : PTR 20111201 |
| Overall survival and good tolerability of long-term use of sorafenib after cytokine treatment: final results of a phase II trial of sorafenib in Japanese patients with metastatic renal cell carcinoma. | BJU international 20111201 |
| Isoniazid-induced pellagra. | Cutaneous and ocular toxicology 20111201 |
| Sorafenib augments cytotoxic effect of S-1 in vitro and in vivo through TS suppression. | Cancer chemotherapy and pharmacology 20111201 |
| Functional and clinical evidence of the influence of sorafenib binding to albumin on sorafenib disposition in adult cancer patients. | Pharmaceutical research 20111201 |
| Treatment of FLT3-ITD-positive acute myeloid leukemia relapsing after allogeneic stem cell transplantation with sorafenib. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20111201 |
| Sequence therapy in patients with metastatic renal cell carcinoma: comparison of common targeted treatment options following failure of receptor tyrosine kinase inhibitors. | European urology 20111201 |
| NAD+ treatment induces delayed autophagy in Neuro2a cells partially by increasing oxidative stress. | Neurochemical research 20111201 |
| Tyrosine kinase inhibitors ameliorate autoimmune encephalomyelitis in a mouse model of multiple sclerosis. | Journal of clinical immunology 20111201 |
| Field-practice study of sorafenib therapy for hepatocellular carcinoma: a prospective multicenter study in Italy. | Hepatology (Baltimore, Md.) 20111201 |
| Spectroscopic (NMR, UV, FT-IR and FT-Raman) analysis and theoretical investigation of nicotinamide N-oxide with density functional theory. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20111201 |
| Phase I trial of sorafenib in patients with recurrent or progressive malignant glioma. | Neuro-oncology 20111201 |
| Sorafenib in combination with weekly topotecan in recurrent ovarian cancer, a phase I/II study of the Hoosier Oncology Group. | Gynecologic oncology 20111201 |
| Structure-based design of isoindoline-1,3-diones and 2,3-dihydrophthalazine-1,4-diones as novel B-Raf inhibitors. | Bioorganic & medicinal chemistry letters 20111201 |
| New imidazo[2,1-b]thiazole derivatives: synthesis, in vitro anticancer evaluation, and in silico studies. | European journal of medicinal chemistry 20111201 |
| Management of cirrhotic patients with hepatocellular carcinoma treated with sorafenib. | Expert review of anticancer therapy 20111201 |
| Signalling and chemosensitivity assays in melanoma: is mutated status a prerequisite for targeted therapy? | Experimental dermatology 20111201 |
| A new rapid and sensitive LC-MS assay for the determination of sorafenib in plasma: application to a patient undergoing hemodialysis. | Therapeutic drug monitoring 20111201 |
| Cost-effectiveness evaluation of sunitinib as first-line targeted therapy for metastatic renal cell carcinoma in Spain. | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20111201 |
| Erythema multiforme-like drug reaction to sorafenib. | Journal of drugs in dermatology : JDD 20111201 |
| The outcomes and safety of single-agent sorafenib in the treatment of elderly patients with advanced hepatocellular carcinoma (HCC). | The oncologist 20111201 |
| Novel EGFR-TK inhibitor EKB-569 inhibits hepatocellular carcinoma cell proliferation by AKT and MAPK pathways. | Journal of Korean medical science 20111201 |
| A novel cosmetic approach to treat thinning hair. | The British journal of dermatology 20111201 |
| VEGF pathway-targeted therapy for advanced renal cell carcinoma: a meta-analysis of randomized controlled trials. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20111201 |
| Sorafenib: complexities of Raf-dependent and Raf-independent signaling are now unveiled. | Medical molecular morphology 20111201 |
| Sorafenib: muscle wasting. | Prescrire international 20111201 |
| Pyridine metabolism and trigonelline synthesis in leaves of the mangrove legume trees Derris indica (Millettia pinnata) and Caesalpinia crista. | Natural product communications 20111201 |
| Treatment of everolimus-resistant metastatic renal cell carcinoma with VEGF-targeted therapies. | British journal of cancer 20111122 |
| Extending the supramolecular synthon based fragment approach (SBFA) for transferability of multipole charge density parameters to monofluorobenzoic acids and their cocrystals with isonicotinamide: importance of C-H···O, C-H···F, and F···F intermolecular regions. | The journal of physical chemistry. A 20111117 |
| Effect of sorafenib on the energy metabolism of hepatocellular carcinoma cells. | European journal of pharmacology 20111116 |
| Glutamatergic pathway targeting in melanoma: single-agent and combinatorial therapies. | Clinical cancer research : an official journal of the American Association for Cancer Research 20111115 |
| Identifying developmental toxicity pathways for a subset of ToxCast chemicals using human embryonic stem cells and metabolomics. | Toxicology and applied pharmacology 20111115 |
| HER2-positive breast cancer cells resistant to trastuzumab and lapatinib lose reliance upon HER2 and are sensitive to the multitargeted kinase inhibitor sorafenib. | Breast cancer research and treatment 20111101 |
| Interaction of sorafenib and cytochrome P450 isoenzymes in patients with advanced melanoma: a phase I/II pharmacokinetic interaction study. | Cancer chemotherapy and pharmacology 20111101 |
| Signal transducer and activator of transcription 3 is a major kinase-independent target of sorafenib in hepatocellular carcinoma. | Journal of hepatology 20111101 |
| Human poisoning with spinosad and flonicamid insecticides. | Human & experimental toxicology 20111101 |
| Sorafenib in renal cell carcinoma. | Critical reviews in oncology/hematology 20111101 |
| Sorafenib for hepatocellular carcinoma according to Child-Pugh class of liver function. | Cancer chemotherapy and pharmacology 20111101 |
| Impact of tyrosine kinase inhibitors on the incidence of brain metastasis in metastatic renal cell carcinoma. | Cancer 20111101 |
| BAY 43-9006/Sorafenib blocks CSF1R activity and induces apoptosis in various classical Hodgkin lymphoma cell lines. | British journal of haematology 20111101 |
| Survival of patients with advanced hepatocellular carcinoma: sorafenib versus other treatments. | Journal of gastroenterology and hepatology 20111101 |
| Synergistic cytotoxicity, inhibition of signal transduction pathways and pharmacogenetics of sorafenib and gemcitabine in human NSCLC cell lines. | Lung cancer (Amsterdam, Netherlands) 20111101 |
| Stability and fitness of pyraclostrobin- and boscalid-resistant phenotypes in field isolates of Botrytis cinerea from apple. | Phytopathology 20111101 |
| Targeting STAT3 in hepatocellular carcinoma: sorafenib again…. | Journal of hepatology 20111101 |
| Coil extrusion from a gastric varice during sorafenib treatment for hepatocellular carcinoma. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20111101 |
| Nicotinamide phosphoribosyltransferase (Nampt) affects the lineage fate determination of mesenchymal stem cells: a possible cause for reduced osteogenesis and increased adipogenesis in older individuals. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20111101 |
| N-Nicotinoyl dopamine, a novel niacinamide derivative, retains high antioxidant activity and inhibits skin pigmentation. | Experimental dermatology 20111101 |
| Sorafenib attenuates p21 in kidney cancer cells and augments cell death in combination with DNA-damaging chemotherapy. | Cancer biology & therapy 20111101 |
| Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epithelium. | Gastroenterology 20111101 |
| Emerging therapies targeting tumor vasculature in multiple myeloma and other hematologic and solid malignancies. | Current cancer drug targets 20111101 |
| A single center experience of sorafenib in advanced hepatocellular carcinoma patients: evaluation of prognostic factors. | European journal of gastroenterology & hepatology 20111101 |
| Design, synthesis, and antiproliferative activity of 3,4-diarylpyrazole-1-carboxamide derivatives against melanoma cell line. | Archiv der Pharmazie 20111101 |
| Safety and efficacy of sorafenib in hepatocellular carcinoma: the impact of the Child-Pugh score. | Alimentary pharmacology & therapeutics 20111101 |
| BRN-103, a novel nicotinamide derivative, inhibits VEGF-induced angiogenesis and proliferation in human umbilical vein endothelial cells. | Bioorganic & medicinal chemistry letters 20111101 |
| Clinical outcome and prognostic factors of sorafenib in Japanese patients with advanced renal cell carcinoma in general clinical practice. | Japanese journal of clinical oncology 20111101 |
| Clinical experience with antiangiogenic therapy in leukemia. | Current cancer drug targets 20111101 |
| The two faces of FBW7 in cancer drug resistance. | BioEssays : news and reviews in molecular, cellular and developmental biology 20111101 |
| Sorafenib, doesn't it have any competitor in advanced hepatocellular carcinoma? | Journal of gastroenterology and hepatology 20111101 |
| Predicting the treatment effect of sorafenib using serum angiogenesis markers in patients with hepatocellular carcinoma. | Journal of gastroenterology and hepatology 20111101 |
| Clinical presentation and management of hand-foot skin reaction associated with sorafenib in combination with cytotoxic chemotherapy: experience in breast cancer. | The oncologist 20111101 |
| Pharmacological characterization of GSK1004723, a novel, long-acting antagonist at histamine H(1) and H(3) receptors. | British journal of pharmacology 20111101 |
| Role of sorafenib in renal cell carcinoma: focus on elderly patients. | Expert review of anticancer therapy 20111101 |
| Chloracne-like drug eruption associated with sorafenib. | Journal of drugs in dermatology : JDD 20111101 |
| Tyrosine kinase inhibitors for metastatic renal cell carcinoma. | Drug and therapeutics bulletin 20111101 |
| Antidiabetic activity of alcoholic leaves extract of Alangium lamarckii Thwaites on streptozotocin-nicotinamide induced type 2 diabetic rats. | Asian Pacific journal of tropical medicine 20111101 |
| Hepatic intra-arterial cetuximab in combination with 5-fluorouracil and cisplatin as salvage treatment for sorafenib-refractory hepatocellular carcinoma. | Anticancer research 20111101 |
| Simultaneous quantitation of nicorandil and its denitrated metabolite in plasma by LC-MS/MS: application for a pharmacokinetic study. | Journal of mass spectrometry : JMS 20111101 |
| [Our experience of the treatment with sorafenib for unresectable hepatocellular carcinoma]. | Gan to kagaku ryoho. Cancer & chemotherapy 20111101 |
| [Three cases of hepatocellular carcinoma without distant metastasis effectively treated by sorafenib]. | Gan to kagaku ryoho. Cancer & chemotherapy 20111101 |
| [The possible role of sorafenib as a part of the multimodal treatment for hepatocellular carcinoma]. | Gan to kagaku ryoho. Cancer & chemotherapy 20111101 |
| [Correction of nonspecific damages in acute poisoning of substance from the group of opiate drug in patients in critical condition]. | Voenno-meditsinskii zhurnal 20111101 |
| Continuous nicotinamide administration improves behavioral recovery and reduces lesion size following bilateral frontal controlled cortical impact injury. | Behavioural brain research 20111031 |
| Bioavailability and pharmacokinetics of sorafenib suspension, nanoparticles and nanomatrix for oral administration to rat. | International journal of pharmaceutics 20111031 |
| Reversible cardiomyopathy associated with sunitinib and sorafenib. | The New England journal of medicine 20111027 |
| Phase II trial of sorafenib combined with concurrent transarterial chemoembolization with drug-eluting beads for hepatocellular carcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20111020 |
| Inhibitors of LRRK2 kinase attenuate neurodegeneration and Parkinson-like phenotypes in Caenorhabditis elegans and Drosophila Parkinson's disease models. | Human molecular genetics 20111015 |
| Genotype and environment effects on the contents of vitamins B1, B2, B3, and B6 in wheat grain. | Journal of agricultural and food chemistry 20111012 |
| Protective effects of resveratrol through the up-regulation of SIRT1 expression in the mutant hSOD1-G93A-bearing motor neuron-like cell culture model of amyotrophic lateral sclerosis. | Neuroscience letters 20111010 |
| Cocrystals of quercetin with improved solubility and oral bioavailability. | Molecular pharmaceutics 20111003 |
| A phase II trial of sorafenib in first-line metastatic urothelial cancer: a study of the PMH Phase II Consortium. | Investigational new drugs 20111001 |
| Pneumatosis intestinalis associated with treatment of cancer patients with the vascular growth factor receptor tyrosine kinase inhibitors sorafenib and sunitinib. | Investigational new drugs 20111001 |
| Ultraviolet recall dermatitis reaction with sorafenib. | Investigational new drugs 20111001 |
| A phase I trial of sorafenib plus gemcitabine and capecitabine for patients with advanced renal cell carcinoma: New York Cancer Consortium Trial NCI 6981. | American journal of clinical oncology 20111001 |
| Dynamic contrast-enhanced magnetic resonance imaging biomarkers predict survival and response in hepatocellular carcinoma patients treated with sorafenib and metronomic tegafur/uracil. | Journal of hepatology 20111001 |
| Tyrosine kinase inhibitors are potent acute pulmonary vasodilators in rats. | American journal of respiratory cell and molecular biology 20111001 |
| Field trial measuring the compatibility of methoxyfenozide and flonicamid with Orius laevigatus Fieber (Hemiptera: Anthocoridae) and Amblyseius swirskii (Athias-Henriot) (Acari: Phytoseiidae) in a commercial pepper greenhouse. | Pest management science 20111001 |
| Sequential use of sorafenib and sunitinib in advanced renal-cell carcinoma (RCC): an Italian multicentre retrospective analysis of 189 patient cases. | BJU international 20111001 |
| 99mTc-HYNIC-spermine for imaging polyamine transport system-positive tumours: preclinical evaluation. | European journal of nuclear medicine and molecular imaging 20111001 |
| Topical clindamycin 1% vs. linoleic acid-rich phosphatidylcholine and nicotinamide 4% in the treatment of acne: a multicentre-randomized trial. | International journal of cosmetic science 20111001 |
| Targeting autophagy enhances sorafenib lethality for hepatocellular carcinoma via ER stress-related apoptosis. | Autophagy 20111001 |
| [Targeting the RAS signalling pathway in cancer]. | Bulletin du cancer 20111001 |
| Liquid chromatography/time-of-flight mass spectrometry for the analysis of plant samples: a method for simultaneous screening of common cofactors or nucleotides and application to an engineered plant line. | Plant physiology and biochemistry : PPB 20111001 |
| Sorafenib as a third line therapy in patients with epithelial ovarian cancer or primary peritoneal cancer: a phase II study. | Gynecologic oncology 20111001 |
| Fibroblast growth factor receptors as therapeutic targets in human melanoma: synergism with BRAF inhibition. | The Journal of investigative dermatology 20111001 |
| Resveratrol prevents norepinephrine induced hypertrophy in adult rat cardiomyocytes, by activating NO-AMPK pathway. | European journal of pharmacology 20111001 |
| Antinociceptive and anti-inflammatory activities of nicotinamide and its isomers in different experimental models. | Pharmacology, biochemistry, and behavior 20111001 |
| Cautions regarding the fitting and interpretation of survival curves: examples from NICE single technology appraisals of drugs for cancer. | PharmacoEconomics 20111001 |
| Sorafenib therapy for hepatocellular carcinoma prior to liver transplant is associated with increased complications after transplant. | Transplant international : official journal of the European Society for Organ Transplantation 20111001 |
| Sorafenib enhances pemetrexed cytotoxicity through an autophagy-dependent mechanism in cancer cells. | Autophagy 20111001 |
| The urokinase plasminogen activator system in metastatic papillary thyroid carcinoma: a potential therapeutic target. | The Journal of clinical endocrinology and metabolism 20111001 |
| Comparing the efficacy of sunitinib with sorafenib in xenograft models of human hepatocellular carcinoma: mechanistic explanation. | Current cancer drug targets 20111001 |
| Prognostic factors in patients with advanced hepatocellular carcinoma treated with sorafenib. | Alimentary pharmacology & therapeutics 20111001 |
| [Renal carcinoma and fatigue: which challenge in the era of antiangiogenic drugs?]. | Bulletin du cancer 20111001 |
| Pemphigoid gestationis: current management. | Dermatologic clinics 20111001 |
| [Clinical characteristics, staging and treatment of patients with hepatocellular carcinoma in clinical practice. Prospective study of 136 patients]. | Gastroenterologia y hepatologia 20111001 |
| Fluvastatin enhances sorafenib cytotoxicity in melanoma cells via modulation of AKT and JNK signaling pathways. | Anticancer research 20111001 |
| [Third-line therapy for metastasized renal cell carcinoma: a randomized, multicenter non-blinded phase III study to compare safety and effectiveness of TF1258 versus sorafenib in patients with metastasized renal cell carcinoma following failure of antiangiogenic (VEGF targeted and mTOR inhibition) therapy (GOLD-AN 31/11 of the Working Group Urological Oncology)]. | Der Urologe. Ausg. A 20111001 |
| [Gastrointestinal hemorrhage associated with concurrent use of sorafenib and warfarin for hepatocellular carcinoma]. | Gan to kagaku ryoho. Cancer & chemotherapy 20111001 |
| [Dermatologic side effects induced by new angiogenesis inhibitors]. | Bulletin du cancer 20111001 |
| [Myocardial metastasis from renal cell carcinoma treated with sorafenib]. | Hinyokika kiyo. Acta urologica Japonica 20111001 |
| Simultaneous determination of flonicamid and its metabolites in vegetables using QuEChERS and reverse-phase liquid chromatography-tandem mass spectrometry. | Journal of chromatography. A 20110923 |
| A phase 1 study of everolimus and sorafenib for metastatic clear cell renal cell carcinoma. | Cancer 20110915 |
| c-Met-Akt pathway-mediated enhancement of inhibitory c-Raf phosphorylation is involved in vitamin K1 and sorafenib synergy on HCC growth inhibition. | Cancer biology & therapy 20110915 |
| Multiresidue method for the determination of 13 pesticides in three environmental matrices: water, sediments and fish muscle. | Talanta 20110915 |
| Sorafenib inhibits growth and metastasis of hepatocellular carcinoma by blocking STAT3. | World journal of gastroenterology 20110914 |
| Structural basis of substrate recognition in human nicotinamide N-methyltransferase. | Biochemistry 20110913 |
| Effect of the tyrosine kinase inhibitors (sunitinib, sorafenib, dasatinib, and imatinib) on blood glucose levels in diabetic and nondiabetic patients in general clinical practice. | Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20110901 |
| Clinical management and case reports for the treatment of hepatocellular carcinoma with sorafenib. | Journal of clinical gastroenterology 20110901 |
| Economic evaluation of new targeted therapies for the first-line treatment of patients with metastatic renal cell carcinoma. | BJU international 20110901 |
| A phase II, multicenter, open-label randomized study of motesanib or bevacizumab in combination with paclitaxel and carboplatin for advanced nonsquamous non-small-cell lung cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20110901 |
| Baseline patient-reported kidney cancer-specific symptoms as an indicator for median survival in sorafenib-refractory metastatic renal cell carcinoma. | Journal of cancer survivorship : research and practice 20110901 |
| [Metastatic renal cell cancer in Germany in 2010. Impact of different target therapies]. | Der Urologe. Ausg. A 20110901 |
| Constitutive ERK activity induces downregulation of tristetraprolin, a major protein controlling interleukin8/CXCL8 mRNA stability in melanoma cells. | American journal of physiology. Cell physiology 20110901 |
| t(8;22)/BCR-FGFR1 myeloproliferative disorder presenting as B-acute lymphoblastic leukemia: report of a case treated with sorafenib and review of the literature. | Leukemia research 20110901 |
| Fatal gastric bleeding during sorafenib treatment for hepatocellular carcinoma recurrence after liver transplantation. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20110901 |
| A role for histone H4K16 hypoacetylation in Saccharomyces cerevisiae kinetochore function. | Genetics 20110901 |
| Phase III study of sorafenib after transarterial chemoembolisation in Japanese and Korean patients with unresectable hepatocellular carcinoma. | European journal of cancer (Oxford, England : 1990) 20110901 |
| Targeted-therapy and imaging response: a new paradigm for clinical evaluation? | Reviews on recent clinical trials 20110901 |
| Prognostic value of 18F-FDG PET for hepatocellular carcinoma patients treated with sorafenib. | Liver international : official journal of the International Association for the Study of the Liver 20110901 |
| Inhibition of doxorubicin-induced autophagy in hepatocellular carcinoma Hep3B cells by sorafenib--the role of extracellular signal-regulated kinase counteraction. | The FEBS journal 20110901 |
| The significance of early alpha-fetoprotein level changes in predicting clinical and survival benefits in advanced hepatocellular carcinoma patients receiving sorafenib. | The oncologist 20110901 |
| Enhanced delivery of cosmeceuticals by microdermabrasion. | Journal of cosmetic dermatology 20110901 |
| Using sorafenib for recurrent hepatocellular carcinoma after liver transplantation--interactions between calcineurin inhibitor: two case reports. | Transplantation proceedings 20110901 |
| Bilateral diffuse uveal melanocytic proliferation with a positive ophthalmoscopic and visual response to plasmapheresis. | Archives of ophthalmology (Chicago, Ill. : 1960) 20110901 |
| Hepatocellular carcinoma and liver transplantation: clinical perspective on molecular targeted strategies. | Medical molecular morphology 20110901 |
| Interstitial granulomatous drug reaction to sorafenib. | Archives of dermatology 20110901 |
| [Safety and efficacy of Sorafenib in treatment of tumor recurrence in liver transplantation recipients]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20110901 |
| Better effect of sorafenib on the rhabdoid component of a clear cell renal cell carcinoma owing to its higher level of vascular endothelial growth factor-A production. | Histopathology 20110901 |
| [Synthesis and biological evaluation of sorafenib thiourea derivatives]. | Yao xue xue bao = Acta pharmaceutica Sinica 20110901 |
| Vitamin B-complex initiates growth and development of human embryonic brain cells in vitro. | Bulletin of experimental biology and medicine 20110901 |
| Response of ETV6-FLT3-positive myeloid/lymphoid neoplasm with eosinophilia to inhibitors of FMS-like tyrosine kinase 3. | Blood 20110825 |
| Phase I pharmacokinetic and pharmacodynamic study of the multikinase inhibitor sorafenib in combination with clofarabine and cytarabine in pediatric relapsed/refractory leukemia. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110820 |
| Brivanib, a dual FGF/VEGF inhibitor, is active both first and second line against mouse pancreatic neuroendocrine tumors developing adaptive/evasive resistance to VEGF inhibition. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110815 |
| Prognostic model for survival in patients with metastatic renal cell carcinoma: results from the international kidney cancer working group. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110815 |
| Caloric restriction primes mitochondria for ischemic stress by deacetylating specific mitochondrial proteins of the electron transport chain. | Circulation research 20110805 |
| Nicotinamide-rich diet improves physical endurance by up-regulating SUR2A in the heart. | Journal of cellular and molecular medicine 20110801 |
| Final results of the European Advanced Renal Cell Carcinoma Sorafenib (EU-ARCCS) expanded-access study: a large open-label study in diverse community settings. | Annals of oncology : official journal of the European Society for Medical Oncology 20110801 |
| Population pharmacokinetic analysis of sorafenib in patients with solid tumours. | British journal of clinical pharmacology 20110801 |
| Molecular characterization of boscalid resistance in field isolates of Botrytis cinerea from apple. | Phytopathology 20110801 |
| Sorafenib-induced acute localized exanthematous pustulosis in a patient with hepatocellular carcinoma. | The British journal of dermatology 20110801 |
| Classic biphasic pulmonary blastoma: a case report and review of the literature. | Lung cancer (Amsterdam, Netherlands) 20110801 |
| In vitro transforming potential, intracellular signaling properties, and sensitivity to a kinase inhibitor (sorafenib) of RET proto-oncogene variants Glu511Lys, Ser649Leu, and Arg886Trp. | Endocrine-related cancer 20110801 |
| Analysis of the efficacy and toxicity of sorafenib in thyroid cancer: a phase II study in a UK based population. | European journal of endocrinology 20110801 |
| Inhibition of experimental HCC growth in mice by use of the kinase inhibitor DMAT. | International journal of oncology 20110801 |
| Complementary vascular and matrix regulatory pathways underlie the beneficial mechanism of action of sorafenib in liver fibrosis. | Hepatology (Baltimore, Md.) 20110801 |
| Design, synthesis, and antiproliferative activity of new 1H-pyrrolo[3,2-c]pyridine derivatives against melanoma cell lines. | European journal of medicinal chemistry 20110801 |
| PR-104 plus sorafenib in patients with advanced hepatocellular carcinoma. | Cancer chemotherapy and pharmacology 20110801 |
| Antiangiogenic agents and endothelin antagonists in advanced castration resistant prostate cancer. | European journal of cancer (Oxford, England : 1990) 20110801 |
| Sorafenib induces apoptotic cell death in human non-small cell lung cancer cells by down-regulating mammalian target of rapamycin (mTOR)-dependent survivin expression. | Biochemical pharmacology 20110801 |
| An investigation of the effect of sorafenib on tumour growth and recurrence after liver cancer resection in nude mice independent of phosphorylated extracellular signal-regulated kinase levels. | Expert opinion on investigational drugs 20110801 |
| Visfatin enhances CXCL8, CXCL10, and CCL20 production in human keratinocytes. | Endocrinology 20110801 |
| cAMP-dependent cytosolic mislocalization of p27(kip)-cyclin D1 during quinol-thioether-induced tuberous sclerosis renal cell carcinoma. | Toxicological sciences : an official journal of the Society of Toxicology 20110801 |
| Quinacrine sensitizes hepatocellular carcinoma cells to TRAIL and chemotherapeutic agents. | Cancer biology & therapy 20110801 |
| Quinacrine synergizes with 5-fluorouracil and other therapies in colorectal cancer. | Cancer biology & therapy 20110801 |
| Azepanone-based inhibitors of human cathepsin S: optimization of selectivity via the P2 substituent. | Bioorganic & medicinal chemistry letters 20110801 |
| Proteasome inhibition in myelodysplastic syndromes and acute myelogenous leukemia cell lines. | Cancer investigation 20110801 |
| Antiangiogenic agents for the treatment of nonsmall cell lung cancer: characterizing the molecular basis for serious adverse events. | Cancer investigation 20110801 |
| Regulation of white and opaque cell-type formation in Candida albicans by Rtt109 and Hst3. | Molecular microbiology 20110801 |
| Sorafenib-induced eruption resembling pityriasis rubra pilaris. | Journal of the American Academy of Dermatology 20110801 |
| Vascular endothelial growth factor-targeted therapies in advanced renal cell carcinoma. | Hematology/oncology clinics of North America 20110801 |
| Systemic therapy for metastatic non-clear-cell renal cell carcinoma: recent progress and future directions. | Hematology/oncology clinics of North America 20110801 |
| Patterns of molecular response to and relapse after combination of sorafenib, idarubicin, and cytarabine in patients with FLT3 mutant acute myeloid leukemia. | Clinical lymphoma, myeloma & leukemia 20110801 |
| [Systemic treatment of renal cell carcinoma - recent update]. | Wiener medizinische Wochenschrift (1946) 20110801 |
| An approach to meta-analysis of dose-finding studies. | Statistics in medicine 20110730 |
| [Adverse effects of new oncologic therapies]. | Praxis 20110727 |
| Sorafenib and dacarbazine as first-line therapy for advanced melanoma: phase I and open-label phase II studies. | British journal of cancer 20110726 |
| Antitumour efficacy of MEK inhibitors in human lung cancer cells and their derivatives with acquired resistance to different tyrosine kinase inhibitors. | British journal of cancer 20110726 |
| Sorafenib reduces the percentage of tumour infiltrating regulatory T cells in renal cell carcinoma patients. | International journal of cancer 20110715 |
| The tyrosine kinase inhibitor sorafenib sensitizes hepatocellular carcinoma cells to taxol by suppressing the HURP protein. | Biochemical pharmacology 20110715 |
| Sorafenib enhances pemetrexed cytotoxicity through an autophagy-dependent mechanism in cancer cells. | Cancer research 20110715 |
| Discovery and evaluation of 3-phenyl-1H-5-pyrazolylamine-based derivatives as potent, selective and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3). | Bioorganic & medicinal chemistry 20110715 |
| Nicotinamide attenuates the ischemic brain injury-induced decrease of Akt activation and Bad phosphorylation. | Neuroscience letters 20110708 |
| Pancreatic exocrine enzyme-producing cell differentiation via embryoid bodies from human embryonic stem cells. | Biochemical and biophysical research communications 20110708 |
| Pharmacokinetic results of a phase I trial of sorafenib in combination with dacarbazine in patients with advanced solid tumors. | Cancer chemotherapy and pharmacology 20110701 |
| Efficacy and safety of motesanib, an oral inhibitor of VEGF, PDGF, and Kit receptors, in patients with imatinib-resistant gastrointestinal stromal tumors. | Cancer chemotherapy and pharmacology 20110701 |
| High-performance liquid chromatographic method for the determination of sorafenib in human serum and peritoneal fluid. | Cancer chemotherapy and pharmacology 20110701 |
| Sorafenib in combination with erlotinib or with gemcitabine in elderly patients with advanced non-small-cell lung cancer: a randomized phase II study. | Annals of oncology : official journal of the European Society for Medical Oncology 20110701 |
| Sorafenib and pegylated interferon-α2b in advanced metastatic melanoma: a multicenter phase II DeCOG trial. | Annals of oncology : official journal of the European Society for Medical Oncology 20110701 |
| Computed tomography findings of sorafenib-treated hepatic tumors in patients with advanced hepatocellular carcinoma. | Journal of gastroenterology and hepatology 20110701 |
| Poly(ADP-ribose) polymerase-1: a novel therapeutic target in necrotizing enterocolitis. | Pediatric research 20110701 |
| Inhibition of eIF4E with ribavirin cooperates with common chemotherapies in primary acute myeloid leukemia specimens. | Leukemia 20110701 |
| Effects of modulating in vivo nitric oxide production on the incidence and severity of PDE4 inhibitor-induced vascular injury in Sprague-Dawley rats. | Toxicological sciences : an official journal of the Society of Toxicology 20110701 |
| Sorafenib derivatives induce apoptosis through inhibition of STAT3 independent of Raf. | European journal of medicinal chemistry 20110701 |
| FLT-PET may not be a reliable indicator of therapeutic response in p53-null malignancy. | International journal of oncology 20110701 |
| One-month relative dose intensity of not less than 50% predicts favourable progression-free survival in sorafenib therapy for advanced renal cell carcinoma in Japanese patients. | European journal of cancer (Oxford, England : 1990) 20110701 |
| Sorafenib enhances the antitumor effects of chemoradiation treatment by downregulating ERCC-1 and XRCC-1 DNA repair proteins. | Molecular cancer therapeutics 20110701 |
| Continuing response to subsequent treatment lines with tyrosine kinase inhibitors in an adolescent with metastatic renal cell carcinoma. | Journal of pediatric hematology/oncology 20110701 |
| Targeting receptor tyrosine kinase pathways in hepatocellular carcinoma. | Anti-cancer agents in medicinal chemistry 20110701 |
| Nicotinamide blocks proliferation and induces apoptosis of chronic lymphocytic leukemia cells through activation of the p53/miR-34a/SIRT1 tumor suppressor network. | Cancer research 20110701 |
| An adjusted indirect comparison of everolimus and sorafenib therapy in sunitinib-refractory metastatic renal cell carcinoma patients using repeated matched samples. | Expert opinion on pharmacotherapy 20110701 |
| The combination of sorafenib with transarterial chemoembolisation for hepatocellular carcinoma. | Alimentary pharmacology & therapeutics 20110701 |
| Assessment of objective responses using volumetric evaluation in advanced thymic malignancies and metastatic non-small cell lung cancer. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20110701 |
| Cancer patients treated with sunitinib or sorafenib have sufficient antibody and cellular immune responses to warrant influenza vaccination. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110701 |
| [Interdisciplinary recommendations for the treatment of metastatic renal cell carcinoma]. | Aktuelle Urologie 20110701 |
| Long-term safety and tolerability of sorafenib in patients with advanced non-small-cell lung cancer: a case-based review. | Clinical lung cancer 20110701 |
| Pancreatic endocrine tumors: a report on a patient treated with sorafenib. | Journal of Korean medical science 20110701 |
| Efficiency of antimicrobial defense: molecular flexibility of natural defensin and artificial bis-quaternary ammonium compound. | Anticancer research 20110701 |
| microRNA-1274a, a modulator of sorafenib induced a disintegrin and metalloproteinase 9 (ADAM9) down-regulation in hepatocellular carcinoma. | FEBS letters 20110623 |
| Fate of iprovalicarb, indoxacarb, and boscalid residues in grapes and wine by GC-ITMS analysis. | Journal of agricultural and food chemistry 20110622 |
| Randomized, double-blind, placebo-controlled, phase II trial of sorafenib and erlotinib or erlotinib alone in previously treated advanced non-small-cell lung cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110620 |
| Activity of Sorafenib against desmoid tumor/deep fibromatosis. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110615 |
| Activity of the multikinase inhibitor sorafenib in combination with cytarabine in acute myeloid leukemia. | Journal of the National Cancer Institute 20110608 |
| Efficacy and safety of sorafenib in a subset of patients with advanced soft tissue sarcoma from a Phase II randomized discontinuation trial. | Investigational new drugs 20110601 |
| Painless acute pancreatitis associated with sorafenib treatment: a case report. | Medical oncology (Northwood, London, England) 20110601 |
| Combination therapy with sorafenib and S-1 for renal cell carcinoma producing granulocyte colony-stimulating factor. | International journal of clinical oncology 20110601 |
| Dietary quinic acid supplied as the nutritional supplement AIO + AC-11® leads to induction of micromolar levels of nicotinamide and tryptophan in the urine. | Phytotherapy research : PTR 20110601 |
| Assessment of the treatment response of HCC. | Abdominal imaging 20110601 |
| Potent in vitro and in vivo antitumor activity of sorafenib against human intrahepatic cholangiocarcinoma cells. | Journal of gastroenterology 20110601 |
| Serum interferon alpha receptor 2 mRNA may predict efficacy of interferon alpha with/without low-dose sorafenib for metastatic clear cell renal cell carcinoma. | Cancer immunology, immunotherapy : CII 20110601 |
| Sequential therapy with JX-594, a targeted oncolytic poxvirus, followed by sorafenib in hepatocellular carcinoma: preclinical and clinical demonstration of combination efficacy. | Molecular therapy : the journal of the American Society of Gene Therapy 20110601 |
| Design, synthesis and evaluation of novel rhodanine-containing sorafenib analogs as potential antitumor agents. | Archiv der Pharmazie 20110601 |
| Sequential therapies with sorafenib and sunitinib in advanced or metastatic renal cell carcinoma. | World journal of urology 20110601 |
| Nicotinamide inhibits hepatic fibrosis by suppressing DNA synthesis and enhancing apoptosis of hepatic stellate cells. | Virchows Archiv : an international journal of pathology 20110601 |
| Treatment of metastatic renal cell carcinoma and renal pelvic cancer. | Clinical and experimental nephrology 20110601 |
| Erythrocyte sedimentation rate kinetics as a marker of treatment response and predictor of prognosis in Chinese metastatic renal cell carcinoma patients treated with sorafenib. | International journal of urology : official journal of the Japanese Urological Association 20110601 |
| Everolimus augments the effects of sorafenib in a syngeneic orthotopic model of hepatocellular carcinoma. | Molecular cancer therapeutics 20110601 |
| Meta-analysis of dermatological toxicities associated with sorafenib. | Clinical and experimental dermatology 20110601 |
| Nicotinamide inhibits growth of carcinogen induced mouse bladder tumor and human bladder tumor xenograft through up-regulation of RUNX3 and p300. | The Journal of urology 20110601 |
| Sir2 is induced by oxidative stress in a yeast model of Huntington disease and its activation reduces protein aggregation. | Archives of biochemistry and biophysics 20110601 |
| Motesanib and advanced NSCLC: experiences and expectations. | Expert opinion on investigational drugs 20110601 |
| Erythema marginatum hemorrhagicum: a unique cutaneous side effect of sorafenib. | Journal of the American Academy of Dermatology 20110601 |
| Copolymer-based hepatocyte asialoglycoprotein receptor targeting agent for SPECT. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20110601 |
| Sorafenib-associated multivessel coronary artery vasospasm. | Herz 20110601 |
| Physico-mechanical and stability evaluation of carbamazepine cocrystal with nicotinamide. | AAPS PharmSciTech 20110601 |
| Editorial comment to erythrocyte sedimentation rate kinetics as a marker of treatment response and predictor of prognosis in Chinese metastatic renal cell carcinoma patients treated with sorafenib. | International journal of urology : official journal of the Japanese Urological Association 20110601 |
| [New therapeutic options for advanced thyroid cancer]. | Deutsche medizinische Wochenschrift (1946) 20110601 |
| Targeting angiogenesis in esophagogastric adenocarcinoma. | The oncologist 20110601 |
| Evaluation of self-treatment of mild-to-moderate facial acne with a blue light treatment system. | Journal of drugs in dermatology : JDD 20110601 |
| [In vitro cytotox icity effects of cocultured DC-C IK cells combined with sorafenib against hepa to cellular carcinoma]. | Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20110601 |
| Assessment of multiparametric MRI in a human glioma model to monitor cytotoxic and anti-angiogenic drug effects. | NMR in biomedicine 20110601 |
| Multikinase inhibitors in metastatic renal cell carcinoma: indirect comparison meta-analysis. | Clinical therapeutics 20110601 |
| Sorafenib for the management of advanced renal cell carcinoma. | Expert review of anticancer therapy 20110601 |
| A painful cranial bulge. | Lancet (London, England) 20110521 |
| Optimized management of advanced hepatocellular carcinoma: four long-lasting responses to sorafenib. | World journal of gastroenterology 20110521 |
| Measurements of tumor cell autophagy predict invasiveness, resistance to chemotherapy, and survival in melanoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110515 |
| The expression of nicotinamide N-methyltransferase increases ATP synthesis and protects SH-SY5Y neuroblastoma cells against the toxicity of Complex I inhibitors. | The Biochemical journal 20110515 |
| Severe sorafenib-induced hand-foot skin reaction. | Dermatology online journal 20110515 |
| Neoadjuvant sorafenib combined with gemcitabine plus oxaliplatin in advanced hepatocellular carcinoma. | World journal of gastroenterology 20110507 |
| Evolving strategies for the treatment of hepatocellular carcinoma: from clinical-guided to molecularly-tailored therapeutic options. | Cancer treatment reviews 20110501 |
| Role of sorafenib and sunitinib in the induction of expressions of NKG2D ligands in nasopharyngeal carcinoma with high expression of ABCG2. | Journal of cancer research and clinical oncology 20110501 |
| Antiangiogenic tyrosine kinase inhibition related gastrointestinal perforations: a case report and literature review. | Angiogenesis 20110501 |
| [Cytoprotective and antiangiogenic effects of the multikinase inhibitor sorafenib on human retinal pigmentepithelium]. | Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20110501 |
| Sorafenib and sunitinib, two anticancer drugs, inhibit CYP3A4-mediated and activate CY3A5-mediated midazolam 1'-hydroxylation. | Drug metabolism and disposition: the biological fate of chemicals 20110501 |
| Sorafenib induces cell death in chronic lymphocytic leukemia by translational downregulation of Mcl-1. | Leukemia 20110501 |
| Comparison of four early posttherapy imaging changes (EPTIC; RECIST 1.0, tumor shrinkage, computed tomography tumor density, Choi criteria) in assessing outcome to vascular endothelial growth factor-targeted therapy in patients with advanced renal cell carcinoma. | European urology 20110501 |
| Sorafenib inhibits transforming growth factor β1-mediated epithelial-mesenchymal transition and apoptosis in mouse hepatocytes. | Hepatology (Baltimore, Md.) 20110501 |
| Clinical results and pharmacokinetics of sorafenib in chronic hemodialysis patients with metastatic renal cell carcinoma in a single center. | Japanese journal of clinical oncology 20110501 |
| Complete regression of locally advanced hepatocellular carcinoma induced by sorafenib allowing curative resection. | Liver international : official journal of the International Association for the Study of the Liver 20110501 |
| Spin-locking versus chemical exchange saturation transfer MRI for investigating chemical exchange process between water and labile metabolite protons. | Magnetic resonance in medicine 20110501 |
| [Indications and current development of new targeted therapies in pediatric oncology]. | Bulletin du cancer 20110501 |
| [Sorafenib in the treatment of hepatocellular carcinoma]. | Vnitrni lekarstvi 20110501 |
| [News on melanoma from the 2010 Dermatology Days in Paris]. | Annales de dermatologie et de venereologie 20110501 |
| [Progression of sorafenib in the treatment of acute myeloid leukemia]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20110501 |
| [Improvement effect of vitamins B1, B2 and PP supplementation on substance metabolism of mice exposed to acute hypoxia]. | Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20110501 |
| [Novelties in the treatment for advanced renal-cell cancer]. | Orvosi hetilap 20110424 |
| Complete histologic response induced by sorafenib in advanced hepatocellular carcinoma: a case report. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110420 |
| B-Raf associates with and activates the NHE1 isoform of the Na+/H+ exchanger. | The Journal of biological chemistry 20110415 |
| [11C]sorafenib: radiosynthesis and preliminary PET study of brain uptake in P-gp/Bcrp knockout mice. | Bioorganic & medicinal chemistry letters 20110415 |
| Sorafenib with interleukin-2 vs sorafenib alone in metastatic renal cell carcinoma: the ROSORC trial. | British journal of cancer 20110412 |
| Double-transduced MDCKII cells to study human P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) interplay in drug transport across the blood-brain barrier. | Molecular pharmaceutics 20110404 |
| Clinical outcomes of sorafenib treatment in patients with metastatic hepatocellular carcinoma who had been previously treated with fluoropyrimidine plus platinum-based chemotherapy. | American journal of clinical oncology 20110401 |
| Experience with sorafenib and adverse event management. | Critical reviews in oncology/hematology 20110401 |
| A phase I open-label study evaluating the cardiovascular safety of sorafenib in patients with advanced cancer. | Cancer chemotherapy and pharmacology 20110401 |
| Secondary resistance to sorafenib in two patients with acute myeloid leukemia (AML) harboring FLT3-ITD mutations. | Annals of hematology 20110401 |
| A new patient-focused approach to the treatment of metastatic renal cell carcinoma: establishing customized treatment options. | BJU international 20110401 |
| Predicting and preventing cardiotoxicity in the era of breast cancer targeted therapies. Novel molecular tools for clinical issues. | Breast (Edinburgh, Scotland) 20110401 |
| The Wlds transgene reduces axon loss in a Charcot-Marie-Tooth disease 1A rat model and nicotinamide delays post-traumatic axonal degeneration. | Neurobiology of disease 20110401 |
| Inhibition of lactic dehydrogenase as a way to increase the anti-proliferative effect of multi-targeted kinase inhibitors. | Pharmacological research 20110401 |
| Activation of phosphatidylinositol 3-kinase/Akt signaling pathway mediates acquired resistance to sorafenib in hepatocellular carcinoma cells. | The Journal of pharmacology and experimental therapeutics 20110401 |
| Myositis due to Sorafenib intake in a patient with hepatocellular carcinoma. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20110401 |
| Initial patterns of care with oral targeted therapies for patients with renal cell carcinoma. | Urology 20110401 |
| Biomarkers in renal cell carcinoma: what next? | Current oncology reports 20110401 |
| Flt3-ITD alters chemotherapy response in vitro and in vivo in a p53-dependent manner. | Experimental hematology 20110401 |
| Inhibition of the Ras/Raf/MEK/ERK and RET kinase pathways with the combination of the multikinase inhibitor sorafenib and the farnesyltransferase inhibitor tipifarnib in medullary and differentiated thyroid malignancies. | The Journal of clinical endocrinology and metabolism 20110401 |
| Tumor size is a potential predictor of response to tyrosine kinase inhibitors in renal cell cancer. | Urology 20110401 |
| Sorafenib may induce hypophosphatemia through a fibroblast growth factor-23 (FGF23)-independent mechanism. | Annals of oncology : official journal of the European Society for Medical Oncology 20110401 |
| Kinase inhibitor Sorafenib modulates immunosuppressive cell populations in a murine liver cancer model. | Laboratory investigation; a journal of technical methods and pathology 20110401 |
| Fatal heart failure after a 26-month combination of tyrosine kinase inhibitors in a papillary thyroid cancer. | Thyroid : official journal of the American Thyroid Association 20110401 |
| Lack of cross-resistance to a novel succinate dehydrogenase inhibitor, fluopyram, in highly boscalid-resistant isolates of Corynespora cassiicola and Podosphaera xanthii. | Pest management science 20110401 |
| Sorafenib-induced premalignant and malignant skin lesions. | International journal of dermatology 20110401 |
| Motesanib, or open-label bevacizumab, in combination with paclitaxel, as first-line treatment for HER2-negative locally recurrent or metastatic breast cancer: a phase 2, randomised, double-blind, placebo-controlled study. | The Lancet. Oncology 20110401 |
| Two drug interaction studies of sirolimus in combination with sorafenib or sunitinib in patients with advanced malignancies. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110401 |
| [Treatment of metastatic renal cell carcinoma]. | Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie 20110401 |
| [Sorafenib induces apoptosis of U937 cells via inhibiting WNT signal pathway]. | Zhongguo shi yan xue ye xue za zhi 20110401 |
| Oxidative stress and ERK1/2 phosphorylation as predictors of outcome in hepatocellular carcinoma patients treated with sorafenib plus octreotide LAR. | Cell death & disease 20110401 |
| A pilot study of adjuvant doxorubicin and cyclophosphamide followed by paclitaxel and sorafenib in women with node-positive or high-risk early-stage breast cancer. | Clinical advances in hematology & oncology : H&O 20110401 |
| Clinical hypothyroidism in a renal cell carcinoma patient treated with sorafenib. | Clinical advances in hematology & oncology : H&O 20110401 |
| Review: thyroid function abnormalities in patients receiving VEGF-targeted therapy. | Clinical advances in hematology & oncology : H&O 20110401 |
| Effects of antidiabetic drugs in high-fat diet and streptozotocin-nicotinamide-induced type 2 diabetic mice. | European journal of pharmacology 20110325 |
| FLT3 ligand impedes the efficacy of FLT3 inhibitors in vitro and in vivo. | Blood 20110324 |
| [Randomize trial of cisplatin plus gemcitabine with either sorafenib or placebo as first-line therapy for non-small cell lung cancer]. | Zhongguo fei ai za zhi = Chinese journal of lung cancer 20110320 |
| Constraining enzyme conformational change by an antibody leads to hyperbolic inhibition. | Journal of molecular biology 20110318 |
| Industrial application of green chromatography--I. Separation and analysis of niacinamide in skincare creams using pure water as the mobile phase. | Talanta 20110315 |
| Structure based design and syntheses of amino-1H-pyrazole amide derivatives as selective Raf kinase inhibitors in melanoma cells. | Bioorganic & medicinal chemistry 20110315 |
| Inhibition of angiogenic and non-angiogenic targets by sorafenib in renal cell carcinoma (RCC) in a RCC xenograft model. | British journal of cancer 20110315 |
| First-line treatment for advanced pancreatic cancer. Highlights from the '2011 ASCO Gastrointestinal Cancers Symposium'. San Francisco, CA, USA. January 20-22, 2011. | JOP : Journal of the pancreas 20110309 |
| SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction. | Nature 20110303 |
| NSCLC drug targets acquire new visibility. | Journal of the National Cancer Institute 20110302 |
| Radiologic complete response with sirolimus and sorafenib in a hepatocellular carcinoma patient who relapsed after orthotopic liver transplantation. | Journal of gastrointestinal cancer 20110301 |
| The multi-targeted kinase inhibitor sorafenib inhibits human cytomegalovirus replication. | Cellular and molecular life sciences : CMLS 20110301 |
| Rapid response to sorafenib in metastatic medullary thyroid carcinoma. | Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20110301 |
| Preclinical efficacy testing in middle-aged rats: nicotinamide, a novel neuroprotectant, demonstrates diminished preclinical efficacy after controlled cortical impact. | Journal of neurotrauma 20110301 |
| Sorafenib for refractory FMS-like tyrosine kinase receptor-3 (FLT3/ITD+) acute myeloid leukemia after allogenic stem cell transplantation. | Leukemia research 20110301 |
| Nicotinamide enhances apoptosis of G(M)-CSF-treated neutrophils and attenuates endotoxin-induced airway inflammation in mice. | American journal of physiology. Lung cellular and molecular physiology 20110301 |
| Marked bone marrow hypoplasia associated with sorafenib-induced marrow blast clearance in two patients with FLT3-ITD acute myeloid leukemia. | Leukemia research 20110301 |
| ¹H nuclear magnetic resonance based metabolic urinary profiling of patients with ischemic heart failure. | Clinical biochemistry 20110301 |
| Multiple origins of European populations of the giant liver fluke Fascioloides magna (Trematoda: Fasciolidae), a liver parasite of ruminants. | International journal for parasitology 20110301 |
| Inhibition of soluble epoxide hydrolase attenuates endothelial dysfunction in animal models of diabetes, obesity and hypertension. | European journal of pharmacology 20110301 |
| Fructose induces gluconeogenesis and lipogenesis through a SIRT1-dependent mechanism. | The Journal of endocrinology 20110301 |
| Immunomodulatory effects of sorafenib on peripheral immune effector cells in metastatic renal cell carcinoma. | European journal of cancer (Oxford, England : 1990) 20110301 |
| Evaluation of KRAS mutations, angiogenic biomarkers, and DCE-MRI in patients with advanced non-small-cell lung cancer receiving sorafenib. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110301 |
| Nicotinamide metabolism in ferns: formation of nicotinic acid glucoside. | Plant physiology and biochemistry : PPB 20110301 |
| Antitumor activity of sphingosine kinase 2 inhibitor ABC294640 and sorafenib in hepatocellular carcinoma xenografts. | Cancer biology & therapy 20110301 |
| Recent advances in cytogenetics and molecular biology of adult hepatocellular tumors: implications for imaging and management. | Radiology 20110301 |
| Sorafenib-associated hand-foot syndrome in Japanese patients. | The Journal of dermatology 20110301 |
| Liver transplantation in a patient treated by sorafenib for hepatocellular carcinoma. | Clinics and research in hepatology and gastroenterology 20110301 |
| Eruptive squamous cell carcinomas with keratoacanthoma-like features in a patient treated with sorafenib. | Journal of drugs in dermatology : JDD 20110301 |
| Management of hepatocellular carcinoma: an update. | Hepatology (Baltimore, Md.) 20110301 |
| [Bullous pemphigoid: a review]. | Annales de dermatologie et de venereologie 20110301 |
| [Pemphigus: a review]. | Annales de dermatologie et de venereologie 20110301 |
| [Hepatocellular carcinoma]. | Nihon Geka Gakkai zasshi 20110301 |
| What is the indication for sorafenib in hepatocellular carcinoma? A clinical challenge. | Oncology (Williston Park, N.Y.) 20110301 |
| Candidacy for sorafenib in HCC patients: is there a slippery slope beyond a SHARP edge? | Oncology (Williston Park, N.Y.) 20110301 |
| Sorafenib for HCC: a pragmatic perspective. | Oncology (Williston Park, N.Y.) 20110301 |
| The low frequency of clinical resistance to PDGFR inhibitors in myeloid neoplasms with abnormalities of PDGFRA might be related to the limited repertoire of possible PDGFRA kinase domain mutations in vitro. | Oncogene 20110224 |
| Doxorubicin plus sorafenib in treatment of advanced hepatocellular carcinoma. | JAMA 20110223 |
| New polymorphs of isonicotinamide and nicotinamide. | Chemical communications (Cambridge, England) 20110207 |
| Proteomic identification of proteins differentially expressed by nicotinamide in focal cerebral ischemic injury. | Neuroscience 20110203 |
| Low-dose taxotere enhances the ability of sorafenib to induce apoptosis in gastric cancer models. | Journal of cellular and molecular medicine 20110201 |
| A phase I trial of sorafenib combined with cisplatin/etoposide or carboplatin/pemetrexed in refractory solid tumor patients. | Lung cancer (Amsterdam, Netherlands) 20110201 |
| Growth of M. avium subspecies paratuberculosis in culture is enhanced by nicotinic acid, nicotinamide, and α and β nicotinamide adenine dinucleotide. | Digestive diseases and sciences 20110201 |
| Antihyperglycemic effects of baicalin on streptozotocin - nicotinamide induced diabetic rats. | Phytotherapy research : PTR 20110201 |
| The diffusion-weighted imaging perfusion fraction f is a potential marker of sorafenib treatment in advanced hepatocellular carcinoma: a pilot study. | European radiology 20110201 |
| Hypothyroidism in patients with renal cell carcinoma: blessing or curse? | Cancer 20110201 |
| Hepatic and HSC-specific sorafenib effects in rats with established secondary biliary cirrhosis. | Laboratory investigation; a journal of technical methods and pathology 20110201 |
| Pretreatment with a novel aquaporin 4 inhibitor, TGN-020, significantly reduces ischemic cerebral edema. | Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20110201 |
| The farnesyl transferase inhibitor lonafarnib inhibits mTOR signaling and enforces sorafenib-induced apoptosis in melanoma cells. | The Journal of investigative dermatology 20110201 |
| Resveratrol inhibits proliferation and promotes apoptosis of neuroblastoma cells: role of sirtuin 1. | Neurochemical research 20110201 |
| Antidiabetic potential of α-amylase inhibitor from the seeds of Macrotyloma uniflorum in streptozotocin-nicotinamide-induced diabetic mice. | Pharmaceutical biology 20110201 |
| Differential inhibition of transmembrane 4 L six family member 5 (TM4SF5)-mediated tumorigenesis by TSAHC and sorafenib. | Cancer biology & therapy 20110201 |
| mTOR inhibitors and sorafenib for recurrent heptocellular carcinoma after orthotopic liver transplantation. | Journal of hepatology 20110201 |
| Direct measurement of thermal stability of expressed CCR5 and stabilization by small molecule ligands. | Biochemistry 20110201 |
| Response to sorafenib at a low dose in patients with radioiodine-refractory pulmonary metastases from papillary thyroid carcinoma. | Thyroid : official journal of the American Thyroid Association 20110201 |
| Sorafenib: activity and clinical application in patients with hepatocellular carcinoma. | Expert opinion on pharmacotherapy 20110201 |
| Emerging strategies in the treatment of advanced hepatocellular carcinoma: the role of targeted therapies. | International journal of clinical practice 20110201 |
| Aminopyridinecarboxamide-based inhaled IKK-2 inhibitors for asthma and COPD: Structure-activity relationship. | Bioorganic & medicinal chemistry 20110201 |
| [Sorafenib and radiotherapy association for hepatocellular carcinoma]. | Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique 20110201 |
| Type XVII collagen ELISA indices significantly decreased after bullous pemphigoid remission. | International journal of dermatology 20110201 |
| Sorafenib suppresses postsurgical recurrence and metastasis of hepatocellular carcinoma in an orthotopic mouse model. | Hepatology (Baltimore, Md.) 20110201 |
| Effect of sorafenib on murine liver regeneration. | Hepatology (Baltimore, Md.) 20110201 |
| Sorafenib induced thyroiditis in two patients with hepatocellular carcinoma. | Thyroid : official journal of the American Thyroid Association 20110201 |
| [Management of hypothyroidism secondary to tyrosine kinase inhibitors: description of treatment in three distinct clinical settings]. | Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion 20110201 |
| [Squamous cell carcinoma in a patient receiving sorafenib]. | Annales de dermatologie et de venereologie 20110201 |
| Targeted therapies for the treatment of metastatic renal cell carcinoma: clinical evidence. | The oncologist 20110201 |
| Beyond traditional outcomes: improving quality of life in patients with renal cell carcinoma. | The oncologist 20110201 |
| Treatment-associated adverse event management in the advanced renal cell carcinoma patient treated with targeted therapies. | The oncologist 20110201 |
| Sorafenib for advanced hepatocellular carcinoma: a systematic review. | Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20110201 |
| [Contribution of microCT structural imaging to preclinical evaluation of hepatocellular carcinoma chemotherapeutics on orthotopic graft in ACI rats]. | Bulletin du cancer 20110201 |
| Multikinase inhibitor sorafenib exerts cytocidal efficacy against Non-Hodgkin lymphomas associated with inhibition of MAPK14 and AKT phosphorylation. | British journal of haematology 20110201 |
| Chronic lymphocytic leukemia cells receive RAF-dependent survival signals in response to CXCL12 that are sensitive to inhibition by sorafenib. | Blood 20110120 |
| EZH2 promotes expansion of breast tumor initiating cells through activation of RAF1-β-catenin signaling. | Cancer cell 20110118 |
| A novel coenzyme A:diacylglycerol acyltransferase 1 inhibitor stimulates lipid metabolism in muscle and lowers weight in animal models of obesity. | European journal of pharmacology 20110115 |
| Muscle type-specific responses to NAD+ salvage biosynthesis promote muscle function in Caenorhabditis elegans. | Developmental biology 20110115 |
| MEK1/2 inhibitors AS703026 and AZD6244 may be potential therapies for KRAS mutated colorectal cancer that is resistant to EGFR monoclonal antibody therapy. | Cancer research 20110115 |
| Interactions between minimum run time, modifier concentration, and efficiency parameters in a high performance liquid chromatography separation. | Journal of chromatography. A 20110114 |
| Splenic infarction associated with sorafenib use in a hepatocellular carcinoma patient. | World journal of gastroenterology 20110114 |
| Evolution of renal function in patients treated with antiangiogenics after nephrectomy for renal cell carcinoma. | Urologic oncology 20110101 |
| Effect of tyrosine kinase inhibitor treatment of renal cell carcinoma on the accumulation of carbonic anhydrase IX-specific chimeric monoclonal antibody cG250. | BJU international 20110101 |
| Effect of CYP3A-inducing anti-epileptics on sorafenib exposure: results of a phase II study of sorafenib plus daily temozolomide in adults with recurrent glioblastoma. | Journal of neuro-oncology 20110101 |
| Pharmacokinetics and dose recommendations of Niaspan® in chronic kidney disease and dialysis patients. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110101 |
| Whole-cell biotransformation assay for investigation of the human drug metabolizing enzyme CYP3A7. | Biochimica et biophysica acta 20110101 |
| The specificity of proton-translocating transhydrogenase for nicotinamide nucleotides. | Biochimica et biophysica acta 20110101 |
| Nicotinamide improves motor deficits and upregulates PGC-1α and BDNF gene expression in a mouse model of Huntington's disease. | Neurobiology of disease 20110101 |
| Sorafenib tosylate and paclitaxel induce anti-angiogenic, anti-tumour and anti-resorptive effects in experimental breast cancer bone metastases. | European journal of cancer (Oxford, England : 1990) 20110101 |
| C/EBPα and PU.1 are involved in distinct differentiation responses of acute promyelocytic leukemia HL-60 and NB4 cells via chromatin remodeling. | Differentiation; research in biological diversity 20110101 |
| Sorafenib induces apoptosis in HL60 cells by inhibiting Src kinase-mediated STAT3 phosphorylation. | Anti-cancer drugs 20110101 |
| In vitro activity of nicotinamide/antileishmanial drug combinations. | Parasitology international 20110101 |
| Comparison of different tumor response criteria in patients with hepatocellular carcinoma after systemic therapy with the multikinase inhibitor sorafenib. | Academic radiology 20110101 |
| Mitochondrial localization and regulation of BRAFV600E in thyroid cancer: a clinically used RAF inhibitor is unable to block the mitochondrial activities of BRAFV600E. | The Journal of clinical endocrinology and metabolism 20110101 |
| The role of the breast cancer resistance protein (ABCG2) in the distribution of sorafenib to the brain. | The Journal of pharmacology and experimental therapeutics 20110101 |
| Phase I study of sorafenib in patients with refractory or relapsed acute leukemias. | Haematologica 20110101 |
| Promising efficacy of sorafenib in a relapsed thymic carcinoma with C-KIT exon 11 deletion mutation. | Lung cancer (Amsterdam, Netherlands) 20110101 |
| Phase I/II study of sorafenib with anastrozole in patients with hormone receptor positive aromatase inhibitor resistant metastatic breast cancer. | Breast cancer research and treatment 20110101 |
| Analysis of phosphoproteomics data. | Methods in molecular biology (Clifton, N.J.) 20110101 |
| The impact of cytoreductive nephrectomy on survival of patients with metastatic renal cell carcinoma receiving vascular endothelial growth factor targeted therapy. | The Journal of urology 20110101 |
| Effect of tea beverages on aldehyde oxidase activity. | Drug metabolism and pharmacokinetics 20110101 |
| Synthesis and antimycobacterial activity of a series of ferrocenyl derivatives. | European journal of medicinal chemistry 20110101 |
| Activity of sorafenib in recurrent ovarian cancer and primary peritoneal carcinomatosis: a gynecologic oncology group trial. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110101 |
| Kidney cancer: Does hypothyroidism predict clinical outcome? | Nature reviews. Urology 20110101 |
| Design of novel N-phenylnicotinamides as selective cyclooxygenase-1 inhibitors. | Bioorganic & medicinal chemistry letters 20110101 |
| MCLMAN, a new minimal medium for Campylobacter jejuni NCTC 11168. | Research in microbiology 20110101 |
| Improved detection of regional melanoma metastasis using 18F-6-fluoro-N-[2-(diethylamino)ethyl] pyridine-3-carboxamide, a melanin-specific PET probe, by perilesional administration. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20110101 |
| Systemic immune tuning in renal cell carcinoma: favorable prognostic impact of TGF-β1 mRNA expression in peripheral blood mononuclear cells. | Journal of immunotherapy (Hagerstown, Md. : 1997) 20110101 |
| Clinical outcome of 251 patients with extrahepatic metastasis at initial diagnosis of hepatocellular carcinoma: does transarterial chemoembolization improve survival in these patients? | Journal of gastroenterology and hepatology 20110101 |
| Prolonged survival in renal transplant recipient with advanced renal cell carcinoma by everolimus and sorafenib. | Nephrology (Carlton, Vic.) 20110101 |
| The sequential combination of a JNK inhibitor and simvastatin protects porcine islets from peritransplant apoptosis and inflammation. | Cell transplantation 20110101 |
| In pursuit of new anti-angiogenic therapies for cancer treatment. | Frontiers in bioscience (Landmark edition) 20110101 |
| Targeting EGFR in bilio-pancreatic and liver carcinoma. | Frontiers in bioscience (Scholar edition) 20110101 |
| Therapeutic advances in women's cancers. | Frontiers in bioscience (Scholar edition) 20110101 |
| How I manage my patients with hepatocellular carcinoma. | Liver international : official journal of the International Association for the Study of the Liver 20110101 |
| Novel molecular therapies in hepatocellular carcinoma. | Liver international : official journal of the International Association for the Study of the Liver 20110101 |
| Sorafenib and its tosylate salt: a multikinase inhibitor for treating cancer. | Acta crystallographica. Section C, Crystal structure communications 20110101 |
| Sorafenib inhibits the hepatocyte growth factor-mediated epithelial mesenchymal transition in hepatocellular carcinoma. | Molecular cancer therapeutics 20110101 |
| Sorafenib in unresectable intrahepatic cholangiocellular carcinoma: a case report. | Wiener klinische Wochenschrift 20110101 |
| Complete response for advanced liver cancer during sorafenib therapy: case report. | BMC gastroenterology 20110101 |
| Invasive squamous cell carcinoma and sorafenib in a black patient. | Archives of dermatology 20110101 |
| Role of cetuximab and sorafenib in treatment of metastatic colorectal cancer. | Indian journal of cancer 20110101 |
| Oral nicotinamide reduces serum phosphorus, increases HDL, and induces thrombocytopenia in hemodialysis patients: a double-blind randomized clinical trial. | Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20110101 |
| Temsirolimus in metastatic chromophobe renal cell carcinoma after interferon and sorafenib therapy. | Anticancer research 20110101 |
| Review: Animal models of N-Methyl-N-nitrosourea-induced mammary cancer and retinal degeneration with special emphasis on therapeutic trials. | In vivo (Athens, Greece) 20110101 |
| Sorafenib therapy in patients with advanced hepatocellular carcinoma in advanced liver cirrhosis. | Digestion 20110101 |
| Cold agglutinin disease in fibrolamellar hepatocellular carcinoma: a rare association with a rare cancer variant. | Annals of Saudi medicine 20110101 |
| Advanced hepatocellular carcinoma. Review of targeted molecular drugs. | Annals of hepatology 20110101 |
| Reversible decrease of portal venous flow in cirrhotic patients: a positive side effect of sorafenib. | PloS one 20110101 |
| [Current approaches to cerebroprotective treatment of premature newborns in reanimation and intensive care departments]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101 |
| [Possibilities of treatment of multiple sclerosis exacerbations without corticosteroids: a role of metabolic and antioxidant therapy]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101 |
| Multidrug resistance protein 2 implicates anticancer drug-resistance to sorafenib. | Biological & pharmaceutical bulletin 20110101 |
| [Oxidative stress and combined antioxidant energy correction in the treatment of periodontitis]. | Stomatologiia 20110101 |
| Current status of molecularly targeted drugs for the treatment of advanced thyroid cancer. | Endocrine journal 20110101 |
| Effects of 1-methylnicotinamide and its metabolite N-methyl-2-pyridone-5-carboxamide on streptozotocin-induced toxicity in murine insulinoma MIN6 cell line. | Acta biochimica Polonica 20110101 |
| [The complex energy correction of chronic brain ischemia]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101 |
| [Sorafenib in combination with chemotherapy in the induction therapy for FLT3-ITD positive acute monocytic leukemia: a case report and literature review]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20110101 |
| Safety and treatment patterns of multikinase inhibitors in patients with metastatic renal cell carcinoma at a tertiary oncology center in Italy. | BMC cancer 20110101 |
| [Detection by SPECT-CT scan with (99m)Tc-(V) DMSA of bone metastases in patient with medullary thyroid cancer]. | Revista espanola de medicina nuclear 20110101 |
| Anticancer activity of the iron facilitator LS081. | Journal of experimental & clinical cancer research : CR 20110101 |
| Management of tyrosine kinase inhibitor-induced hand-foot skin reaction: viewpoints from the medical oncologist, dermatologist, and oncology nurse. | The journal of supportive oncology 20110101 |
| All that glitters: sorafenib. | Internal medicine (Tokyo, Japan) 20110101 |
| [The results of using cytoflavin in conservative treatment of patients with obliterating atherosclerosis of the lower extremity vessels]. | Vestnik khirurgii imeni I. I. Grekova 20110101 |
| Suspected interaction between sorafenib and HAART in an HIV-1 infected patient: a case report. | Hepato-gastroenterology 20110101 |
| [Correction of central nervous system energy processes in children with the minimal cerebral dysfunction]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101 |
| [Clinical efficacy of cytoflavin in the combined treatment of patients during acute phase of ischemic stroke]. | Klinicheskaia meditsina 20110101 |
| NAMPT in regulated NAD biosynthesis and its pivotal role in human metabolism. | Current medicinal chemistry 20110101 |
| Physicochemical characterization and dissolution study of solid dispersions of ketoconazole with nicotinamide. | Chemical & pharmaceutical bulletin 20110101 |
| Resistance of renal cell carcinoma to sorafenib is mediated by potentially reversible gene expression. | PloS one 20110101 |
| Design and rationale of the HCC BRIDGE study in China: a longitudinal, multicenter cohort trial in hepatocellular carcinoma. | BMC gastroenterology 20110101 |
| [The use of cytoflavin for the treatment of chronic brucellosis]. | Klinicheskaia meditsina 20110101 |
| Efficacy of temsirolimus after previous treatment with sunitinib, sorafenib or everolimus in advanced renal cell cancer. | Oncology 20110101 |
| [Antioxidant protection in surgical correction of inborn heart disease with the use of artificial circulation]. | Khirurgiia 20110101 |
| [Clinical-encephalographic evaluation of preterm children treated with cytoflavin during the first year of life]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101 |
| [Antioxidant and membranoprotector treatment of chronic pyelonephritis]. | Eksperimental'naia i klinicheskaia farmakologiia 20110101 |
| Prognostic factors in patients with advanced hepatocellular carcinoma treated with sorafenib: a retrospective comparison with previously known prognostic models. | Oncology 20110101 |
| Preparation of the albumin nanoparticle system loaded with both paclitaxel and sorafenib and its evaluation in vitro and in vivo. | Journal of microencapsulation 20110101 |
| [Antioxidant protection as a component of anesthetic management cancer patients]. | Khirurgiia 20110101 |
| [Postoperative correction of the methabolism of the single lung after pulmonectomy]. | Khirurgiia 20110101 |
| Pharmacological characterization of [³H]CHIBA-3007 binding to glycine transporter 1 in the rat brain. | PloS one 20110101 |
| How to manage hypersensitivity reactions to biological agents? | European journal of dermatology : EJD 20110101 |
| Intrinsic resistance to tyrosine kinase inhibitors is associated with poor clinical outcome in metastatic renal cell carcinoma. | BMC cancer 20110101 |
| Safety and pharmacokinetics of motesanib in combination with gemcitabine and erlotinib for the treatment of solid tumors: a phase 1b study. | BMC cancer 20110101 |
| Targeting renal cell carcinoma with NVP-BEZ235, a dual PI3K/mTOR inhibitor, in combination with sorafenib. | Molecular cancer 20110101 |
| Targeted drug therapies and cancer. | Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20110101 |
| Nicotinamide phosphoribosyltransferase/visfatin does not catalyze nicotinamide mononucleotide formation in blood plasma. | PloS one 20110101 |
| Signaling pathway and molecular-targeted therapy for hepatocellular carcinoma. | Digestive diseases (Basel, Switzerland) 20110101 |
| Molecularly targeted therapies for hepatocellular carcinoma: sorafenib as a stepping stone. | Digestive diseases (Basel, Switzerland) 20110101 |
| Des-γ-carboxyprothrombin may be a promising biomarker to determine the therapeutic efficacy of sorafenib for hepatocellular carcinoma. | Digestive diseases (Basel, Switzerland) 20110101 |
| Rationale and design of decision: a double-blind, randomized, placebo-controlled phase III trial evaluating the efficacy and safety of sorafenib in patients with locally advanced or metastatic radioactive iodine (RAI)-refractory, differentiated thyroid cancer. | BMC cancer 20110101 |
| Psoriasiform skin eruption associated with sorafenib therapy. | Indian journal of dermatology, venereology and leprology 20110101 |
| [Positive effect of cytoflavin on metabolic status changes in patients with burn disorder]. | Eksperimental'naia i klinicheskaia farmakologiia 20110101 |
| [Pharmacologic neuroprotection of the brain in carotid artery surgeries]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101 |
| Cutaneous toxicities of the multikinase inhibitors sorafenib and sunitinib. | Dermatologic therapy 20110101 |
| Economic evaluation of everolimus versus sorafenib for the treatment of metastatic renal cell carcinoma after failure of first-line sunitinib. | Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20110101 |
| Sorafenib-induced erythema multiforme: three cases. | European journal of dermatology : EJD 20110101 |
| Differential modulatory effects of GSK-3β and HDM2 on sorafenib-induced AIF nuclear translocation (programmed necrosis) in melanoma. | Molecular cancer 20110101 |
| Sirtuin-mediated nuclear differentiation and programmed degradation in Tetrahymena. | BMC cell biology 20110101 |
| [Pharmacotherapy of basic clinical presentations of chronic brain ischemia]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101 |
| [Effect of cytoflavin on the recovery of cognitive function after the cardiaс surgery with artificial blood circulation]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101 |
| AFP measurement in monitoring treatment response of advanced hepatocellular carcinoma to sorafenib: case report and review of the literature. | Onkologie 20110101 |
| High circulating endothelial progenitor levels associated with poor survival of advanced hepatocellular carcinoma patients receiving sorafenib combined with metronomic chemotherapy. | Oncology 20110101 |
| Recurrent hepatocellular carcinoma in liver transplant recipients: parameters affecting time to recurrence, treatment options and survival in the sorafenib era. | Tumori 20110101 |
| [Cytoflavin in the complex treatment of neuroinfections in children]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101 |
| Identification of gene expression signature modulated by nicotinamide in a mouse bladder cancer model. | PloS one 20110101 |
| Diagnostic and prognostic molecular markers in hepatocellular carcinoma. | Disease markers 20110101 |
| New biotechnological perspectives of a NADH oxidase variant from Thermus thermophilus HB27 as NAD+-recycling enzyme. | BMC biotechnology 20110101 |
| Efficient derivation of human cardiac precursors and cardiomyocytes from pluripotent human embryonic stem cells with small molecule induction. | Journal of visualized experiments : JoVE 20110101 |
| Early decrease in α-fetoprotein, but not des-γ-carboxy prothrombin, predicts sorafenib efficacy in patients with advanced hepatocellular carcinoma. | Oncology 20110101 |
| Nicotinamide inhibits alkylating agent-induced apoptotic neurodegeneration in the developing rat brain. | PloS one 20110101 |
| [Comparative experimental study of antioxidant efficiency in treatment of acute pancreatitis]. | Eksperimental'naia i klinicheskaia farmakologiia 20110101 |
| Antitumor activity of sorafenib in human cancer cell lines with acquired resistance to EGFR and VEGFR tyrosine kinase inhibitors. | PloS one 20110101 |
| High dose intermittent sorafenib shows improved efficacy over conventional continuous dose in renal cell carcinoma. | Journal of translational medicine 20110101 |
| Sublingual reactive histiocytosis in a dog. | Journal of veterinary dentistry 20110101 |
| Signaling pathways in hepatocellular carcinoma. | Oncology 20110101 |
| Adjuvant therapy after curative treatment for hepatocellular carcinoma. | Oncology 20110101 |
| Radiotherapeutic strategies in the management of hepatocellular carcinoma. | Oncology 20110101 |
| Multidisciplinary management of nonresectable hepatocellular carcinoma. | Oncology 20110101 |
| Treatment algorithm for intermediate and advanced stage hepatocellular carcinoma: Korea. | Oncology 20110101 |
| Complete response of advanced hepatocellular carcinoma with multiple lung metastases treated with sorafenib: a case report. | Oncology 20110101 |
| [Pharmacological neuroprotection against brain damage in ischemiai/reperfusion experiment]. | Eksperimental'naia i klinicheskaia farmakologiia 20110101 |
| [Pharmacological correction of free radical disturbances and endotoxicosis in patients with diffuse peritonitis at the postoperative period]. | Vestnik khirurgii imeni I. I. Grekova 20110101 |
| [Experience of cytoflavin administration for treating acute carbon monoxide poisoning]. | Eksperimental'naia i klinicheskaia farmakologiia 20110101 |
| Nicotinamide in dermatology and photoprotection. | Skinmed 20110101 |
| An overview of evidence-based management of hepatocellular carcinoma: a meta-analysis. | Journal of cancer research and therapeutics 20110101 |
| Sorafenib, risk of bleeding and spontaneous rupture of hepatocellular carcinoma. A clinical case. | Acta medica (Hradec Kralove) 20110101 |
| Colon perforation during sorafenib therapy for advanced hepatocelluar carcinoma. A case report. | Tumori 20110101 |
| Hand-foot syndrome due to sorafenib in hepatocellular carcinoma treated with vitamin E without dose modification; a preliminary clinical study. | Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20110101 |
| [Prevention of cognitive dysfunction in patients operated on thyroid gland]. | Khirurgiia 20110101 |
| [Methods for the prevention and treatment of toxico-hypoxic encephalopathy in patients with acute severe poisoning]. | Klinicheskaia meditsina 20110101 |
| In vitro (α-glucosidase and α-amylase inhibition) and in vivo antidiabetic property of phytic acid (IP6) in streptozotocin- nicotinamide-induced type 2 diabetes mellitus (NIDDM) in rats. | Journal of complementary & integrative medicine 20110101 |
| [Course of free radical processes and prognosis of ischemic and hemorrhagic stroke]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101 |
| Plasma biomarkers correlating with clinical outcome in a phase II study of sorafenib in advanced NSCLC. | Cancer biomarkers : section A of Disease markers 20110101 |
| Enhancing mda-7/IL-24 therapy in renal carcinoma cells by inhibiting multiple protective signaling pathways using sorafenib and by Ad.5/3 gene delivery. | Cancer biology & therapy 20101215 |
| A front-line window of opportunity phase 2 study of sorafenib in patients with advanced nonsmall cell lung cancer: North Central Cancer Treatment Group Study N0326. | Cancer 20101215 |
| Vitamin K enhancement of sorafenib-mediated HCC cell growth inhibition in vitro and in vivo. | International journal of cancer 20101215 |
| Identification of the aryl hydrocarbon receptor target gene TiPARP as a mediator of suppression of hepatic gluconeogenesis by 2,3,7,8-tetrachlorodibenzo-p-dioxin and of nicotinamide as a corrective agent for this effect. | The Journal of biological chemistry 20101210 |
| Antihyperlipidemic effect of chlorogenic acid and tetrahydrocurcumin in rats subjected to diabetogenic agents. | Chemico-biological interactions 20101205 |
| Ursolic acid ameliorates thymic atrophy and hyperglycemia in streptozotocin-nicotinamide-induced diabetic mice. | Chemico-biological interactions 20101205 |
| Mutations in the Saccharomyces cerevisiae succinate dehydrogenase result in distinct metabolic phenotypes revealed through (1)H NMR-based metabolic footprinting. | Journal of proteome research 20101203 |
| Phase I clinical and pharmacokinetic study of sorafenib in combination with carboplatin and paclitaxel in patients with advanced non-small cell lung cancer. | Investigational new drugs 20101201 |
| Synergistic efficacy of sorafenib and genistein in growth inhibition by down regulating angiogenic and survival factors and increasing apoptosis through upregulation of p53 and p21 in malignant neuroblastoma cells having N-Myc amplification or non-amplification. | Investigational new drugs 20101201 |
| Probable sorafenib-induced reversible encephalopathy in a patient with hepatocellular carcinoma. | Medical oncology (Northwood, London, England) 20101201 |
| Experience with sorafenib and the elderly patient. | Medical oncology (Northwood, London, England) 20101201 |
| Downstaging of hepatocellular carcinoma prior to liver transplant: is there a role for adjuvant sorafenib in locoregional therapy? | Journal of gastrointestinal cancer 20101201 |
| Impact of sorafenib on health-related quality of life in Japanese patients with metastatic renal cell carcinoma: a prospective evaluation. | BJU international 20101201 |
| Dynamic contrast-enhanced CT in patients treated with sorafenib and erlotinib for non-small cell lung cancer: a new method of monitoring treatment? | European radiology 20101201 |
| 18[F]FDG small animal PET study of sorafenib efficacy in lymphoma preclinical models. | The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of... 20101201 |
| Initial testing (stage 1) of the multi-targeted kinase inhibitor sorafenib by the pediatric preclinical testing program. | Pediatric blood & cancer 20101201 |
| Presurgical targeted therapy with tyrosine kinase inhibitors for advanced renal cell carcinoma: clinical results and histopathological therapeutic effects. | Japanese journal of clinical oncology 20101201 |
| Is it time to reassess alpha lipoic acid and niacinamide therapy in schizophrenia? | Medical hypotheses 20101201 |
| Sorafenib in patients with metastatic renal cell carcinoma refractory to either sunitinib or bevacizumab. | Cancer 20101201 |
| Sorafenib induces growth inhibition and apoptosis of human chondrosarcoma cells by blocking the RAF/ERK/MEK pathway. | Journal of surgical oncology 20101201 |
| [Recommendations for the management of Sorafenib in patients with hepatocellular carcinoma]. | Gastroenterologia y hepatologia 20101201 |
| Third-line sorafenib after sequential therapy with sunitinib and mTOR inhibitors in metastatic renal cell carcinoma. | European urology 20101201 |
| Combined patch containing salicylic acid and nicotinamide: role of drug interaction. | Current drug delivery 20101201 |
| Sorafenib: rays of hope in thyroid cancer. | Thyroid : official journal of the American Thyroid Association 20101201 |
| Oncogenic RAF: a brief history of time. | Pigment cell & melanoma research 20101201 |
| Mechanism of synergistic antitumor effect of sorafenib and interferon-α on treatment of renal cell carcinoma. | The Journal of urology 20101201 |
| Sorafenib efficacy in ovarian clear cell carcinoma revealed by transcriptome profiling. | Cancer science 20101201 |
| New drugs in advanced non-small-cell lung cancer: searching for the correct clinical development. | Expert opinion on investigational drugs 20101201 |
| Sorafenib extends the survival time of patients with multiple recurrences of hepatocellular carcinoma after liver transplantation. | Acta pharmacologica Sinica 20101201 |
| Sorafenib as adjuvant therapy for high-risk hepatocellular carcinoma in liver transplant recipients: feasibility and efficacy. | Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20101201 |
| Treating hepatocellular carcinoma with sorafenib in liver transplant patients: an initial experience. | Transplantation proceedings 20101201 |
| Regional squamous cell carcinomas following systemic sorafenib therapy and isolated limb infusion for regionally advanced metastatic melanoma of the limb. | Archives of dermatology 20101201 |
| PI-103 and sorafenib inhibit hepatocellular carcinoma cell proliferation by blocking Ras/Raf/MAPK and PI3K/AKT/mTOR pathways. | Anticancer research 20101201 |
| More than 4 years of progression-free survival in a patient with metastatic renal cell carcinoma treated sequentially with sunitinib, everolimus, sorafenib, and temsirolimus. | Anticancer research 20101201 |
| Comparative efficiency of succinate-containing antihypoxants in traumatic toxicosis. | Bulletin of experimental biology and medicine 20101201 |
| Which treatment modality should we choose for advanced hepatocellular carcinoma? | The Korean journal of hepatology 20101201 |
| Hydride ion-carrier ability in Rh(I) complexes of a nicotinamide-functionalised N-heterocyclic carbene ligand. | Dalton transactions (Cambridge, England : 2003) 20101128 |
| Sirolimus plus sorafenib in treating HCC recurrence after liver transplantation: a case report. | World journal of gastroenterology 20101121 |
| Radiotherapy with concurrent carbogen and nicotinamide in bladder carcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101120 |
| Doxorubicin plus sorafenib vs doxorubicin alone in patients with advanced hepatocellular carcinoma: a randomized trial. | JAMA 20101117 |
| Subtype-selective Na(v)1.8 sodium channel blockers: identification of potent, orally active nicotinamide derivatives. | Bioorganic & medicinal chemistry letters 20101115 |
| Induction of DNA damage-inducible gene GADD45beta contributes to sorafenib-induced apoptosis in hepatocellular carcinoma cells. | Cancer research 20101115 |
| NAD(+) -dependent histone deacetylases (sirtuins) as novel therapeutic targets. | Medicinal research reviews 20101101 |
| Synergistic activity of letrozole and sorafenib on breast cancer cells. | Breast cancer research and treatment 20101101 |
| Association of percentage of tumour burden removed with debulking nephrectomy and progression-free survival in patients with metastatic renal cell carcinoma treated with vascular endothelial growth factor-targeted therapy. | BJU international 20101101 |
| Pilot, multicenter, double-blind, randomized placebo-controlled bilateral comparative study of a combination of calcipotriene and nicotinamide for the treatment of psoriasis. | Journal of the American Academy of Dermatology 20101101 |
| Antimycobacterial and antitumor activities of palladium(II) complexes containing isonicotinamide (isn): X-ray structure of trans-[Pd(N3)2(isn)(2)]. | European journal of medicinal chemistry 20101101 |
| Angiogenesis as a therapeutic target in urothelial carcinoma. | Anti-cancer drugs 20101101 |
| Biomarkers as predictors of response to treatment with motesanib in patients with progressive advanced thyroid cancer. | The Journal of clinical endocrinology and metabolism 20101101 |
| Sorafenib inhibits cAMP-dependent ERK activation, cell proliferation, and in vitro cyst growth of human ADPKD cyst epithelial cells. | American journal of physiology. Renal physiology 20101101 |
| Targeting B-Raf as a treatment strategy for polycystic kidney disease. | American journal of physiology. Renal physiology 20101101 |
| Monitoring blood-brain barrier status in a rat model of glioma receiving therapy: dual injection of low-molecular-weight and macromolecular MR contrast media. | Radiology 20101101 |
| Spiny follicular hyperkeratosis eruption: a new cutaneous adverse effect of sorafenib. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101101 |
| Feasibility of (125)I brachytherapy combined with sorafenib treatment in patients with multiple lung metastases after liver transplantation for hepatocellular carcinoma. | Journal of cancer research and clinical oncology 20101101 |
| Quantitation of sorafenib and its active metabolite sorafenib N-oxide in human plasma by liquid chromatography-tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20101101 |
| Population pharmacokinetic/pharmacodynamic modeling for the time course of tumor shrinkage by motesanib in thyroid cancer patients. | Cancer chemotherapy and pharmacology 20101101 |
| Development of a modeling framework to simulate efficacy endpoints for motesanib in patients with thyroid cancer. | Cancer chemotherapy and pharmacology 20101101 |
| Sorafenib in platinum-treated patients with extensive stage small cell lung cancer: a Southwest Oncology Group (SWOG 0435) phase II trial. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20101101 |
| Sorafenib overcomes TRAIL resistance of hepatocellular carcinoma cells through the inhibition of STAT3. | Clinical cancer research : an official journal of the American Association for Cancer Research 20101101 |
| [Multimodality treatment for hepatocellular carcinoma]. | Der Internist 20101101 |
| Bevacizumab for metastatic renal cell carcinoma: a monoclonal antibody in a sea of small molecules. | Expert opinion on biological therapy 20101101 |
| 111In-bevacizumab imaging of renal cell cancer and evaluation of neoadjuvant treatment with the vascular endothelial growth factor receptor inhibitor sorafenib. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20101101 |
| Sorafenib prevents human retinal pigment epithelium cells from light-induced overexpression of VEGF, PDGF and PlGF. | The British journal of ophthalmology 20101101 |
| Continuous administration of sorafenib in combination with transarterial chemoembolization in patients with hepatocellular carcinoma: results of a phase I study. | The oncologist 20101101 |
| Economic evaluation of sorafenib in unresectable hepatocellular carcinoma. | Journal of gastroenterology and hepatology 20101101 |
| A phase I dose-escalation study to evaluate safety and tolerability of sorafenib combined with sirolimus in patients with advanced solid cancer. | British journal of cancer 20101101 |
| Development of a resistance-like phenotype to sorafenib by human hepatocellular carcinoma cells is reversible and can be delayed by metronomic UFT chemotherapy. | Neoplasia (New York, N.Y.) 20101101 |
| Sorafenib modulates the gene expression of multi-drug resistance mediating ATP-binding cassette proteins in experimental hepatocellular carcinoma. | Anticancer research 20101101 |
| The therapy of kidney cancer with biomolecular drugs. | Cancer treatment reviews 20101101 |
| [Effect of sorafenib on lymphangiogenesis in subcutaneously transplanted human cholangiocarcinoma in nude mice]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20101101 |
| [The outcome of chemotherapy by sorafenib in advanced hepatocellular carcinoma]. | Gan to kagaku ryoho. Cancer & chemotherapy 20101101 |
| [The effect of sorafenib and intermittent hepatic arterial infusion chemotherapy using cisplatin for advanced hepatocellular carcinoma with portal vein tumor thrombus--a pilot study]. | Gan to kagaku ryoho. Cancer & chemotherapy 20101101 |
| [Determination of nicacid and its metabolites in human plasma by HPLC-MS/MS]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20101101 |
| Study to evaluate the impact of heat treatment on water soluble vitamins in milk. | JPMA. The Journal of the Pakistan Medical Association 20101101 |
| [New possibilities of targeted therapy in the treatment of hepatocellular carcinoma with the help of molecular biology]. | Orvosi hetilap 20101024 |
| Risk of arterial thrombosis not increased by sorafenib or sunitinib. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101020 |
| Synergistic antitumor activity of sorafenib in combination with epidermal growth factor receptor inhibitors in colorectal and lung cancer cells. | Clinical cancer research : an official journal of the American Association for Cancer Research 20101015 |
| Toxic effects of sorafenib when given early after allogeneic hematopoietic stem cell transplantation. | Blood 20101014 |
| A phase I/II trial of sorafenib and infliximab in advanced renal cell carcinoma. | British journal of cancer 20101012 |
| High-resolution crystal structures of Streptococcus pneumoniae nicotinamidase with trapped intermediates provide insights into the catalytic mechanism and inhibition by aldehydes . | Biochemistry 20101012 |
| Interventions for bullous pemphigoid. | The Cochrane database of systematic reviews 20101006 |
| Nelfinavir induces mitochondria protection by ERK1/2-mediated mcl-1 stabilization that can be overcome by sorafenib. | Investigational new drugs 20101001 |
| Sorafenib plus octreotide is an effective and safe treatment in advanced hepatocellular carcinoma: multicenter phase II So.LAR. study. | Cancer chemotherapy and pharmacology 20101001 |
| Phase 1 study of the investigational, oral angiogenesis inhibitor motesanib in Japanese patients with advanced solid tumors. | Cancer chemotherapy and pharmacology 20101001 |
| Tolerable sorafenib therapy for a renal cell carcinoma patient with hemodialysis: a case study. | International journal of clinical oncology 20101001 |
| A case of blast clearance on sorafenib in relapsed FLT3-ITD acute myeloid leukemia: evidence of efficacy continues to mount. | Leukemia research 20101001 |
| Bone marrow niche-inspired, multiphase expansion of megakaryocytic progenitors with high polyploidization potential. | Cytotherapy 20101001 |
| Effect of sorafenib on experimental choroidal neovascularization in the rat. | Clinical & experimental ophthalmology 20101001 |
| Sorafenib induces sustained molecular remission in FLT3-ITD positive AML with relapse after second allogeneic stem cell transplantation without exacerbation of acute GVHD: a case report. | Leukemia research 20101001 |
| The multikinase inhibitor sorafenib reverses the suppression of IL-12 and enhancement of IL-10 by PGE₂ in murine macrophages. | International immunopharmacology 20101001 |
| Biomarkers predicting outcome in patients with advanced renal cell carcinoma: Results from sorafenib phase III Treatment Approaches in Renal Cancer Global Evaluation Trial. | Clinical cancer research : an official journal of the American Association for Cancer Research 20101001 |
| Health-related quality of life and sorafenib. | Hepatology (Baltimore, Md.) 20101001 |
| Antinociceptive effects of histamine H3 receptor antagonist in the preclinical models of pain in rats and the involvement of central noradrenergic systems. | Brain research 20101001 |
| Parenchymal versus nonparenchymal target lesion response in clinical trials for metastatic medullary thyroid cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101001 |
| Down-regulation of p38 mitogen-activated protein kinase activation and proinflammatory cytokine production by mitogen-activated protein kinase inhibitors in inflammatory bowel disease. | Clinical and experimental immunology 20101001 |
| A phase II study of sorafenib in malignant mesothelioma: results of Cancer and Leukemia Group B 30307. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20101001 |
| [Nonsurgical management of hepatocellular carcinoma]. | Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique 20101001 |
| The Bcl-xL inhibitor, ABT-737, efficiently induces apoptosis and suppresses growth of hepatoma cells in combination with sorafenib. | Hepatology (Baltimore, Md.) 20101001 |
| Sorafenib enhances the in vitro anti-endothelial effects of low dose (metronomic) chemotherapy. | Oncology reports 20101001 |
| Simultaneous determination of niacin and its metabolites--nicotinamide, nicotinuric acid and N-methyl-2-pyridone-5-carboxamide--in human plasma by LC-MS/MS and its application to a human pharmacokinetic study. | Biomedical chromatography : BMC 20101001 |
| Investigation of 99mTc-labelling of recombinant human interleukin-2 via hydrazinonicotinamide. | Nuclear medicine and biology 20101001 |
| Hyperkeratotic eruption, hand-foot skin reaction, facial erythema, and stomatitis secondary to multi-targeted kinase inhibitor sorafenib. | International journal of dermatology 20101001 |
| Atypical linear toxicodermia by sorafenib. | International journal of dermatology 20101001 |
| Developing better treatments in hepatocellular carcinoma. | Expert review of gastroenterology & hepatology 20101001 |
| [Tegafur-uracil markedly reduced pulmonary metastasis from renal cell carcinoma refractory to sorafenib, interferon and interleukin 2]. | Gan to kagaku ryoho. Cancer & chemotherapy 20101001 |
| [Hepatocellular carcinoma]. | Nihon rinsho. Japanese journal of clinical medicine 20101001 |
| [Molecular targeted therapy for renal cell carcinoma and other urological cancers]. | Nihon rinsho. Japanese journal of clinical medicine 20101001 |
| Inherited hepatocellular carcinoma. | Best practice & research. Clinical gastroenterology 20101001 |
| Efficacy of sorafenib, molecular targeting drug, for advanced hepatocellular carcinoma. | Gan to kagaku ryoho. Cancer & chemotherapy 20101001 |
| Novel multitargeted anticancer oral therapies: sunitinib and sorafenib as a paradigm. | The Israel Medical Association journal : IMAJ 20101001 |
| [Correcting posthypoxic damage of myocardium in newborns with cerebral ischemia]. | Eksperimental'naia i klinicheskaia farmakologiia 20101001 |
| [Using cytoflavin for correcting x-ray contrasting agent-induced nephropathy]. | Eksperimental'naia i klinicheskaia farmakologiia 20101001 |
| NADH oxidase activity of Bacillus subtilis nitroreductase NfrA1: insight into its biological role. | FEBS letters 20100924 |
| Investigation of the catalytic mechanism of Sir2 enzyme with QM/MM approach: SN1 vs SN2? | The journal of physical chemistry. B 20100916 |
| Human SIRT6 promotes DNA end resection through CtIP deacetylation. | Science (New York, N.Y.) 20100910 |
| Safety and efficacy of the combination of erlotinib and sirolimus for the treatment of metastatic renal cell carcinoma after failure of sunitinib or sorafenib. | British journal of cancer 20100907 |
| [Treatment of primary hepatocellular carcinoma]. | Orvosi hetilap 20100905 |
| Efficacy and safety of sorafenib in patients with advanced renal cell carcinoma with and without prior cytokine therapy, a subanalysis of TARGET. | Medical oncology (Northwood, London, England) 20100901 |
| Spontaneous pyopneumothorax in patients treated with mTOR inhibitors for subpleural pulmonary metastases. | Medical oncology (Northwood, London, England) 20100901 |
| Targeted agents in metastatic Xp11 translocation/TFE3 gene fusion renal cell carcinoma (RCC): a report from the Juvenile RCC Network. | Annals of oncology : official journal of the European Society for Medical Oncology 20100901 |
| Carbonic anhydrase IX and pathological features as predictors of outcome in patients with metastatic clear-cell renal cell carcinoma receiving vascular endothelial growth factor-targeted therapy. | BJU international 20100901 |
| Tolerance and outcome of patients with unresectable hepatocellular carcinoma treated with sorafenib. | European journal of gastroenterology & hepatology 20100901 |
| BRAF as therapeutic target in melanoma. | Biochemical pharmacology 20100901 |
| Antihyperglycemic effect of diosmin on hepatic key enzymes of carbohydrate metabolism in streptozotocin-nicotinamide-induced diabetic rats. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20100901 |
| The hand-foot-syndrome associated with medical tumor therapy - classification and management. | Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20100901 |
| In vitro and in vivo antitumor efficacy of docetaxel and sorafenib combination in human pancreatic cancer cells. | Current cancer drug targets 20100901 |
| Role of CD38, a cyclic ADP-ribosylcyclase, in morphine antinociception and tolerance. | The Journal of pharmacology and experimental therapeutics 20100901 |
| A-887826 is a structurally novel, potent and voltage-dependent Na(v)1.8 sodium channel blocker that attenuates neuropathic tactile allodynia in rats. | Neuropharmacology 20100901 |
| Synthesis, characterization, and molecular modeling of a pharmaceutical co-crystal: (2-chloro-4-nitrobenzoic acid):(nicotinamide). | Journal of pharmaceutical sciences 20100901 |
| A novel pathway for nicotine degradation by Aspergillus oryzae 112822 isolated from tobacco leaves. | Research in microbiology 20100901 |
| Hydrotropic solubilization of poorly water-soluble drugs. | Journal of pharmaceutical sciences 20100901 |
| Treatment outcomes of sorafenib for first line or cytokinerefractory advanced renal cell carcinoma in Japanese patients. | International journal of urology : official journal of the Japanese Urological Association 20100901 |
| Long-term safety of sorafenib in advanced renal cell carcinoma: follow-up of patients from phase III TARGET. | European journal of cancer (Oxford, England : 1990) 20100901 |
| Solubility, metastable zone width measurement and crystal growth of the 1:1 benzoic acid/isonicotinamide cocrystal in solutions of variable stoichiometry. | Journal of pharmaceutical sciences 20100901 |
| Molecular targeted therapy of advanced hepatocellular carcinoma beyond sorafenib. | Expert opinion on pharmacotherapy 20100901 |
| Sorafenib and radiation: a promising combination in colorectal cancer. | International journal of radiation oncology, biology, physics 20100901 |
| Editorial comment to Treatment outcomes of sorafenib for first line or cytokine-refractory advanced renal cell carcinoma in Japanese patients. | International journal of urology : official journal of the Japanese Urological Association 20100901 |
| [Sorafenib]. | Deutsche medizinische Wochenschrift (1946) 20100901 |
| Multiple resistance of Botrytis cinerea from kiwifruit to SDHIs, QoIs and fungicides of other chemical groups. | Pest management science 20100901 |
| Significance of manipulating tumour hypoxia and radiation dose rate in terms of local tumour response and lung metastatic potential, referring to the response of quiescent cell populations. | The British journal of radiology 20100901 |
| [Sorafenib in relapsed and refractory FLT3-ITD positive acute myeloid leukemia: a novel treatment option]. | Deutsche medizinische Wochenschrift (1946) 20100901 |
| Sorafenib therapy in patients with hepatocellular carcinoma before liver transplantation. | Hepatology (Baltimore, Md.) 20100901 |
| Sorafenib-induced destructive thyroiditis. | Thyroid : official journal of the American Thyroid Association 20100901 |
| Synthesizing and salvaging NAD: lessons learned from Chlamydomonas reinhardtii. | PLoS genetics 20100901 |
| Transient perforating folliculitis induced by sorafenib. | The Journal of dermatology 20100901 |
| [Clinical observation of transarterial chemoembolization combined with sorafenib for advanced hepatocellular carcinoma]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20100901 |
| Clinical roundtable monograph. Integrating recent data in managing adverse events in the treatment of hepatocellular carcinoma. | Clinical advances in hematology & oncology : H&O 20100901 |
| Effect of selected NAD+ analogues on mitochondria activity and proliferation of endothelial EA.hy926 cells. | European journal of pharmacology 20100825 |
| 1-methylnicotinamide effects on the selected markers of endothelial function, inflammation and haemostasis in diabetic rats. | European journal of pharmacology 20100825 |
| [Clinical analysis of the treatment:transcatheter arterial chemoembolization combined with sorafenib in advanced hepatocellular carcinoma]. | Zhonghua yi xue za zhi 20100817 |
| Novel hinge binder improves activity and pharmacokinetic properties of BRAF inhibitors. | Journal of medicinal chemistry 20100812 |
| Development and characterization of new inhibitors of the human and mouse hematopoietic prostaglandin D(2) synthases. | Journal of medicinal chemistry 20100812 |
| From a cancer drug fund to value based pricing of drugs. | BMJ (Clinical research ed.) 20100812 |
| Primitive neuroectodermal tumor of the kidney with inferior vena cava tumor thrombus during pregnancy response to sorafenib. | Chinese medical journal 20100805 |
| Structural basis for sirtuin function: what we know and what we don't. | Biochimica et biophysica acta 20100801 |
| Biochemical effects of SIRT1 activators. | Biochimica et biophysica acta 20100801 |
| Complete response of hepatocellular carcinoma with systemic combination chemotherapy: not to get out the chemotherapy? | European journal of gastroenterology & hepatology 20100801 |
| Low body mass index and sarcopenia associated with dose-limiting toxicity of sorafenib in patients with renal cell carcinoma. | Annals of oncology : official journal of the European Society for Medical Oncology 20100801 |
| Sunitinib and sorafenib in metastatic renal cell carcinoma patients with renal insufficiency. | Annals of oncology : official journal of the European Society for Medical Oncology 20100801 |
| Sirtuin chemical mechanisms. | Biochimica et biophysica acta 20100801 |
| Ameliorative potential of resveratrol on proinflammatory cytokines, hyperglycemia mediated oxidative stress, and pancreatic beta-cell dysfunction in streptozotocin-nicotinamide-induced diabetic rats. | Journal of cellular physiology 20100801 |
| Comparative and combined effect of chlorogenic acid and tetrahydrocurcumin on antioxidant disparities in chemical induced experimental diabetes. | Molecular and cellular biochemistry 20100801 |
| In vitro to in vivo comparison of the substrate characteristics of sorafenib tosylate toward P-glycoprotein. | Drug metabolism and disposition: the biological fate of chemicals 20100801 |
| Involvement of receptor tyrosine phosphatase DEP-1 mediated PI3K-cofilin signaling pathway in sorafenib-induced cytoskeletal rearrangement in hepatoma cells. | Journal of cellular physiology 20100801 |
| Sorafenib plus valproic acid for infant spinal glioblastoma. | Journal of pediatric hematology/oncology 20100801 |
| A case of variant angina in a patient under chronic treatment with sorafenib. | Nature reviews. Clinical oncology 20100801 |
| Sorafenib-induced hypothyroidism is associated with increased type 3 deiodination. | The Journal of clinical endocrinology and metabolism 20100801 |
| Sorafenib for recurrent hepatocellular carcinoma after liver transplantation. | Japanese journal of clinical oncology 20100801 |
| Persistent correction of hyperglycemia in streptozotocin-nicotinamide-induced diabetic mice by a non-conventional radical scavenger. | Naunyn-Schmiedeberg's archives of pharmacology 20100801 |
| Pancreatic cancer: utility of dynamic contrast-enhanced MR imaging in assessment of antiangiogenic therapy. | Radiology 20100801 |
| Identification of a secondary FLT3/A848P mutation in a patient with FLT3-ITD-positive blast phase CMML and response to sunitinib and sorafenib. | Leukemia 20100801 |
| A pharmacodynamic study of sorafenib in patients with relapsed and refractory acute leukemias. | Leukemia 20100801 |
| Metastatic renal carcinoma: evaluation of antiangiogenic therapy with dynamic contrast-enhanced CT. | Radiology 20100801 |
| ZAK is required for doxorubicin, a novel ribotoxic stressor, to induce SAPK activation and apoptosis in HaCaT cells. | Cancer biology & therapy 20100801 |
| Concurrent radiotherapy and temozolomide followed by temozolomide and sorafenib in the first-line treatment of patients with glioblastoma multiforme. | Cancer 20100801 |
| Molecular targeted therapy for advanced hepatocellular carcinoma: current status and future perspectives. | Journal of gastroenterology 20100801 |
| Minor crops for export: a case study of boscalid, pyraclostrobin, lufenuron and lambda-cyhalothrin residue levels on green beans and spring onions in Egypt. | Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20100801 |
| Experimental unilateral spermatic cord torsion: the effect of polypolymerase enzyme inhibitor on histopathological and biochemical changes in the early and late periods in the ipsilateral and contralateral testicles. | Urology 20100801 |
| Piperidinyl-nicotinamides as potent and selective somatostatin receptor subtype 5 antagonists. | Bioorganic & medicinal chemistry letters 20100801 |
| Sorafenib: a clinical and pharmacologic review. | Expert opinion on pharmacotherapy 20100801 |
| Sensitivity of doxorubicin-resistant cells to sorafenib: possible role for inhibition of eukaryotic initiation factor-2alpha phosphorylation. | International journal of oncology 20100801 |
| Differences in effects on myocardium and mitochondria by angiogenic inhibitors suggest separate mechanisms of cardiotoxicity. | Toxicologic pathology 20100801 |
| The design, synthesis, and evaluation of 8 hybrid DFG-out allosteric kinase inhibitors: a structural analysis of the binding interactions of Gleevec, Nexavar, and BIRB-796. | Bioorganic & medicinal chemistry 20100801 |
| Vorinostat and sorafenib increase CD95 activation in gastrointestinal tumor cells through a Ca(2+)-de novo ceramide-PP2A-reactive oxygen species-dependent signaling pathway. | Cancer research 20100801 |
| [Cutaneous side effects of the multikinase inhibitors sorafenib and sunitinib]. | Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20100801 |
| Tumor-stromal cell interactions and opportunities for therapeutic intervention. | Current opinion in pharmacology 20100801 |
| BAD, a proapoptotic member of the BCL2 family, is a potential therapeutic target in hepatocellular carcinoma. | Molecular cancer research : MCR 20100801 |
| Stimulatory effects of the multi-kinase inhibitor sorafenib on human bladder cancer cells. | British journal of pharmacology 20100801 |
| The cocrystal nicotinamide-succinic acid (2/1). | Acta crystallographica. Section C, Crystal structure communications 20100801 |
| Sorafenib activates CD95 and promotes autophagy and cell death via Src family kinases in gastrointestinal tumor cells. | Molecular cancer therapeutics 20100801 |
| Impact of the incorporation of tyrosine kinase inhibitor agents on the treatment of patients with a diagnosis of advanced renal cell carcinoma: study based on experience at the Hospital Universitario Central de Asturias. | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20100801 |
| Novel therapies for hypereosinophilic syndromes. | The Netherlands journal of medicine 20100801 |
| [Therapeutic efficacy of Nexavar on liver cancer and its relation to the expression of Ki-67 and CD34]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20100801 |
| Sorafenib in hepatocellular carcinoma. | British journal of hospital medicine (London, England : 2005) 20100801 |
| Metabolomic study on vitamins B₁, B₂, and PP supplementation to improve serum metabolic profiles in mice under acute hypoxia based on ¹H NMR analysis. | Biomedical and environmental sciences : BES 20100801 |
| [Therapeutic efficacy and prognostic factors of sorafenib treatment in patients with unresectable primary hepatocellular carcinoma]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20100801 |
| Resveratrol attenuates hyperglycemia-mediated oxidative stress, proinflammatory cytokines and protects hepatocytes ultrastructure in streptozotocin-nicotinamide-induced experimental diabetic rats. | Chemico-biological interactions 20100730 |
| Sustained treatment response of metastatic hepatocellular carcinoma with bevacizumab and sorafenib. | World journal of gastroenterology 20100728 |
| Augmentation of radiation response by motesanib, a multikinase inhibitor that targets vascular endothelial growth factor receptors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20100715 |
| Safety, efficacy, pharmacokinetics, and pharmacodynamics of the combination of sorafenib and tanespimycin. | Clinical cancer research : an official journal of the American Association for Cancer Research 20100715 |
| Sorafenib-induced severe acute hepatitis in a stable liver transplant recipient. | Transplantation 20100715 |
| Sorafenib exerts anti-glioma activity in vitro and in vivo. | Neuroscience letters 20100712 |
| Phase II evaluation of sorafenib in advanced and metastatic squamous cell carcinoma of the head and neck: Southwest Oncology Group Study S0420. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100710 |
| Medical treatments: in association or alone, their roles and their future perspectives: the Western experience. | Journal of hepato-biliary-pancreatic sciences 20100701 |
| Molecular dynamics simulations of hydrotropic solubilization and self-aggregation of nicotinamide. | Journal of pharmaceutical sciences 20100701 |
| Sorafenib combined vitamin K induces apoptosis in human pancreatic cancer cell lines through RAF/MEK/ERK and c-Jun NH2-terminal kinase pathways. | Journal of cellular physiology 20100701 |
| Antiangiogenesis agents in colorectal cancer. | Current opinion in oncology 20100701 |
| Phase II study of combining sorafenib with metronomic tegafur/uracil for advanced hepatocellular carcinoma. | Journal of hepatology 20100701 |
| New insights into the antifibrotic effects of sorafenib on hepatic stellate cells and liver fibrosis. | Journal of hepatology 20100701 |
| The multikinase inhibitor sorafenib induces caspase-dependent apoptosis in PC-3 prostate cancer cells. | Asian journal of andrology 20100701 |
| Sorafenib induces apoptosis and autophagy in prostate cancer cells in vitro. | International journal of oncology 20100701 |
| The present and the future landscape of treatment of advanced hepatocellular carcinoma. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20100701 |
| Cardiovascular safety of VEGF-targeting therapies: current evidence and handling strategies. | The oncologist 20100701 |
| Evaluation of 11C-GSK189254 as a novel radioligand for the H3 receptor in humans using PET. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100701 |
| When reversible ligands do not reverse, and other modelers' dilemmas. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100701 |
| Pioglitazone, a PPAR-gamma ligand inhibited the nicotinamide-streptozotocin induced sperm abnormalities in type-2 diabetic Wistar rats. | Pakistan journal of pharmaceutical sciences 20100701 |
| Depletion of tumor-associated macrophages enhances the effect of sorafenib in metastatic liver cancer models by antimetastatic and antiangiogenic effects. | Clinical cancer research : an official journal of the American Association for Cancer Research 20100701 |
| Sorafenib, a multikinase inhibitor, enhances the response of melanoma to regional chemotherapy. | Molecular cancer therapeutics 20100701 |
| Sorafenib-induced erythema multiforme for metastatic renal cell carcinoma. | Annals of oncology : official journal of the European Society for Medical Oncology 20100701 |
| Sorafenib: where do we go from here? | Hepatology (Baltimore, Md.) 20100701 |
| Fatty liver and fibrosis in glycine N-methyltransferase knockout mice is prevented by nicotinamide. | Hepatology (Baltimore, Md.) 20100701 |
| Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP. | Genes & development 20100701 |
| Modulation of histone H3 lysine 56 acetylation as an antifungal therapeutic strategy. | Nature medicine 20100701 |
| A phase II trial of first-line sorafenib in patients with metastatic renal cell carcinoma unwilling to receive or with early intolerance to immunotherapy: SOGUG Study 06-01. | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20100701 |
| Management of hepatocellular carcinoma: from prevention to molecular targeted therapy. | Oncology 20100701 |
| Positioning of a molecular-targeted agent, sorafenib, in the treatment algorithm for hepatocellular carcinoma and implication of many complete remission cases in Japan. | Oncology 20100701 |
| Positioning and indication of sorafenib in the treatment algorithm and real practice setting: Western and eastern approach--Asian perspective. | Oncology 20100701 |
| Tetracycline and niacinamide control bullous pemphigoid but not pemphigus foliaceus when these conditions coexist. | The Journal of dermatology 20100701 |
| Design and rationale for the non-interventional Global Investigation of Therapeutic DEcisions in Hepatocellular Carcinoma and Of its Treatment with Sorafenib (GIDEON) study. | International journal of clinical practice 20100701 |
| [The usefulness of nicotinamide in radioiodine therapy in patients with toxic and nontoxic large goitres]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20100701 |
| [Efficacy of cytoflavine in treating traumatic toxicosis]. | Eksperimental'naia i klinicheskaia farmakologiia 20100701 |
| Sorafenib in combination with gemcitabine in recurrent epithelial ovarian cancer: a study of the Princess Margaret Hospital Phase II Consortium. | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20100701 |
| Phase II study of sorafenib in combination with docetaxel and cisplatin in the treatment of metastatic or advanced gastric and gastroesophageal junction adenocarcinoma: ECOG 5203. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100620 |
| Synergistic activity of sorafenib and sulforaphane abolishes pancreatic cancer stem cell characteristics. | Cancer research 20100615 |
| [Hepatocellular carcinoma: occurrence, risk factors, biomarkers]. | Orvosi hetilap 20100606 |
| Frequent dose interruptions are required for patients receiving oral kinase inhibitor therapy for advanced renal cell carcinoma. | American journal of clinical oncology 20100601 |
| Sorafenib therapy for metastatic renal carcinoma in patients with low cardiac ejection fraction: report of two cases and literature review. | Cancer investigation 20100601 |
| Hepatocellular carcinoma: sorafenib before liver transplantation? | Hepatology (Baltimore, Md.) 20100601 |
| Nicotinamide-rich diet protects the heart against ischaemia-reperfusion in mice: a crucial role for cardiac SUR2A. | Pharmacological research 20100601 |
| Combination therapy of interleukin-2 and sorafenib improves survival benefits and prevents spontaneous pulmonary metastasis in murine renal cell carcinoma models. | Japanese journal of clinical oncology 20100601 |
| Sorafenib protects human optic nerve head astrocytes from light-induced overexpression of vascular endothelial growth factor, platelet-derived growth factor, and placenta growth factor. | Growth factors (Chur, Switzerland) 20100601 |
| Update on systemic therapies of metastatic renal cell carcinoma. | World journal of urology 20100601 |
| Fatal hemobilia in advanced hepatocellular carcinoma invading biliary tract after treatment with sorafenib and biliary stenting. | Annals of oncology : official journal of the European Society for Medical Oncology 20100601 |
| A comparative study of flavonoid analogues on streptozotocin-nicotinamide induced diabetic rats: quercetin as a potential antidiabetic agent acting via 11beta-hydroxysteroid dehydrogenase type 1 inhibition. | European journal of medicinal chemistry 20100601 |
| Tyrosine kinase inhibitors gefitinib, lapatinib and sorafenib induce rapid functional alterations in breast cancer cells. | Current cancer drug targets 20100601 |
| Treatment with tyrosine kinase inhibitors for patients with differentiated thyroid cancer: the M. D. Anderson experience. | The Journal of clinical endocrinology and metabolism 20100601 |
| A multicenter phase II study of erlotinib and sorafenib in chemotherapy-naive patients with advanced non-small cell lung cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20100601 |
| Sequential therapy of transarterial chemoembolisation and sorafenib in intermediate stage hepatocellular carcinoma. | Journal of gastrointestinal cancer 20100601 |
| Differentiation of mesenchymal stem cells to insulin-producing cells and their impact on type 1 diabetic rats. | Journal of physiology and biochemistry 20100601 |
| Sorafenib with doxorubicin augments cytotoxicity to renal cell cancer through PERK inhibition. | International journal of oncology 20100601 |
| Treatment of metastatic renal cell carcinoma. | Nature reviews. Urology 20100601 |
| [Antiangionic drugs in soft tissue sarcoma]. | Bulletin du cancer 20100601 |
| [Focus on GIST management]. | Bulletin du cancer 20100601 |
| Morphology, Attenuation, Size, and Structure (MASS) criteria: assessing response and predicting clinical outcome in metastatic renal cell carcinoma on antiangiogenic targeted therapy. | AJR. American journal of roentgenology 20100601 |
| A genome-wide RNA interference screen reveals an essential CREB3L2-ATF5-MCL1 survival pathway in malignant glioma with therapeutic implications. | Nature medicine 20100601 |
| Harvesting the low-hanging fruit: kinase inhibitors for therapy of advanced medullary and nonmedullary thyroid cancer. | The Journal of clinical endocrinology and metabolism 20100601 |
| [Anti-angiogenic drugs]. | Nihon rinsho. Japanese journal of clinical medicine 20100601 |
| [Current therapy for hepatocellular carcinoma]. | Nihon rinsho. Japanese journal of clinical medicine 20100601 |
| Expert opinion on the use of first-line sorafenib in selected metastatic renal cell carcinoma patients. | Expert review of anticancer therapy 20100601 |
| [Effect of sorafenib combined with daunorubicin on K562 cell line]. | Zhongguo shi yan xue ye xue za zhi 20100601 |
| Efficacy and safety of sorafenib in advanced hepatocellular carcinoma under daily practice conditions. | Journal of chemotherapy (Florence, Italy) 20100601 |
| Nonoperative therapies for combined modality treatment of hepatocellular cancer: expert consensus statement. | HPB : the official journal of the International Hepato Pancreato Biliary Association 20100601 |
| Nonoperative therapies for combined modality treatment of hepatocellular cancer: expert consensus conference. | HPB : the official journal of the International Hepato Pancreato Biliary Association 20100601 |
| Improving the stability of probiotic bacteria in model fruit juices using vitamins and antioxidants. | Journal of food science 20100601 |
| Sorafenib and thyrotoxicosis. | Journal of endocrinological investigation 20100601 |
| Annular leukocytoclastic vasculitis associated with sorafenib administration. | Journal of drugs in dermatology : JDD 20100601 |
| Sorafenib-associated psoriasiform skin changes. | Cutis 20100601 |
| Sorafenib's inhibition of prostate cancer growth in transgenic adenocarcinoma mouse prostate mice and its differential effects on endothelial and pericyte growth during tumor angiogenesis. | Analytical and quantitative cytology and histology 20100601 |
| Structure elucidation of highly polar basic degradants by on-line hydrogen/deuterium exchange hydrophilic interaction chromatography coupled to tandem mass spectrometry. | Journal of chromatography. A 20100528 |
| Interactions and encapsulation of vitamins C, B3, and B6 with dendrimers in water. | Chemistry (Weinheim an der Bergstrasse, Germany) 20100525 |
| Chronic niacin overload may be involved in the increased prevalence of obesity in US children. | World journal of gastroenterology 20100521 |
| Nox1 is involved in p53 deacetylation and suppression of its transcriptional activity and apoptosis. | Free radical biology & medicine 20100515 |
| Activation of NF-kappaB signaling by inhibitor of NF-kappaB kinase beta increases aggressiveness of ovarian cancer. | Cancer research 20100515 |
| Phase II clinical trial of sorafenib in metastatic medullary thyroid cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100510 |
| [Treatment approach of hepatocellular carcinoma in Spain. Analysis of 705 patients from 62 centers]. | Medicina clinica 20100508 |
| Optimal de novo design of MRM experiments for rapid assay development in targeted proteomics. | Journal of proteome research 20100507 |
| Sorafenib-induced acute pancreatitis. | JOP : Journal of the pancreas 20100505 |
| Analysis of imatinib and sorafenib binding to p38alpha compared with c-Abl and b-Raf provides structural insights for understanding the selectivity of inhibitors targeting the DFG-out form of protein kinases. | Biochemistry 20100504 |
| Inhibitory effect of nicotinamide on enzymatic activity of selected fungal strains causing skin infection. | Mycoses 20100501 |
| Incidence of brain metastases in renal cell carcinoma treated with sorafenib. | Annals of oncology : official journal of the European Society for Medical Oncology 20100501 |
| The loss of radiographic enhancement in primary renal cell carcinoma tumors following multitargeted receptor tyrosine kinase therapy is an additional indicator of response. | Urology 20100501 |
| Randomized, double-blinded, placebo controlled study to assess the effect of topical 1% nicotinamide on actinic keratoses. | The British journal of dermatology 20100501 |
| Sorafenib in combination with carboplatin and paclitaxel as neoadjuvant chemotherapy in patients with advanced ovarian cancer. | Cancer chemotherapy and pharmacology 20100501 |
| FT-IR and FT-Raman vibrational spectra and molecular structure investigation of nicotinamide: A combined experimental and theoretical study. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20100501 |
| Blockade of the MEK/ERK signalling cascade by AS703026, a novel selective MEK1/2 inhibitor, induces pleiotropic anti-myeloma activity in vitro and in vivo. | British journal of haematology 20100501 |
| New 5-HT(1A) receptor ligands containing a N'-cyanoisonicotinamidine nucleus: synthesis and in vitro pharmacological evaluation. | Bioorganic & medicinal chemistry letters 20100501 |
| The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma. | Journal of hepatology 20100501 |
| Personalized molecular targeted therapy in advanced, recurrent hepatocellular carcinoma after liver transplantation: a proof of principle. | Journal of hepatology 20100501 |
| Risk of arterial thromboembolic events with sunitinib and sorafenib: a systematic review and meta-analysis of clinical trials. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100501 |
| Beyond sorafenib: novel targeted therapies for advanced hepatocellular carcinoma. | Expert opinion on investigational drugs 20100501 |
| Novel inhibitors in development for hepatocellular carcinoma. | Expert opinion on investigational drugs 20100501 |
| Systemic treatment of hepatocellular carcinoma: dawn of a new era? | Annals of surgical oncology 20100501 |
| A phase Ib study of AMG 102 in combination with bevacizumab or motesanib in patients with advanced solid tumors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20100501 |
| Sorafenib in patients with advanced non-small cell lung cancer that harbor K-ras mutations: a brief report. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20100501 |
| Drug therapy: sorafenib. | Hepatology (Baltimore, Md.) 20100501 |
| Editorial comment. | Urology 20100501 |
| Editorial comment. | Urology 20100501 |
| Clinical overview of sorafenib in breast cancer. | Future oncology (London, England) 20100501 |
| [Interdisciplinary recommendations for the treatment of metastatic renal cell carcinoma]. | Aktuelle Urologie 20100501 |
| Sorafenib for the treatment of advanced hepatocellular carcinoma. | Health technology assessment (Winchester, England) 20100501 |
| Non-pigmenting fixed drug eruption induced by sorafenib. | Acta dermato-venereologica 20100501 |
| [Pharmacological correction of hypoxic and free-radical disorders in patients with acute myocardial infarction complicated by acute heart failure]. | Eksperimental'naia i klinicheskaia farmakologiia 20100501 |
| Present state of target therapy for disseminated renal cell carcinoma. | Immunotherapy 20100501 |
| Managing patients receiving sorafenib for advanced hepatocellular carcinoma: a case study. | International journal of palliative nursing 20100501 |
| Sorafenib in metastatic renal cell carcinoma with sarcomatoid differentiation. | Journal of the Chinese Medical Association : JCMA 20100501 |
| Antidiabetic activity of cycloart-23-ene-3beta, 25-diol (B2) isolated from Pongamia pinnata (L. Pierre) in streptozotocin-nicotinamide induced diabetic mice. | European journal of pharmacology 20100425 |
| Protective effect of nicotinamide against poly(ADP-ribose) polymerase-1-mediated astrocyte death depends on its transporter-mediated uptake. | Life sciences 20100424 |
| Clinical responses observed with imatinib or sorafenib in melanoma patients expressing mutations in KIT. | British journal of cancer 20100413 |
| Phase III study of carboplatin and paclitaxel alone or with sorafenib in advanced non-small-cell lung cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100410 |
| Phase I/II study of combination therapy with sorafenib, idarubicin, and cytarabine in younger patients with acute myeloid leukemia. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100410 |
| Hemangiopericytoma and antiangiogenic therapy: clinical benefit of antiangiogenic therapy (sorafenib and sunitinib) in relapsed malignant haemangioperyctoma /solitary fibrous tumour. | Investigational new drugs 20100401 |
| Residue analysis of kresoxim-methyl and boscalid in fruits, vegetables and soil using liquid-liquid extraction and gas chromatography-mass spectrometry. | Biomedical chromatography : BMC 20100401 |
| Phase II study of motesanib in Japanese patients with advanced gastrointestinal stromal tumors with prior exposure to imatinib mesylate. | Cancer chemotherapy and pharmacology 20100401 |
| The dual PI3K/mTOR inhibitor PI-103 promotes immunosuppression, in vivo tumor growth and increases survival of sorafenib-treated melanoma cells. | International journal of cancer 20100401 |
| Consensus on the current use of sorafenib for the treatment of hepatocellular carcinoma. | European journal of gastroenterology & hepatology 20100401 |
| Nicotinamide prevents the long-term effects of perinatal asphyxia on apoptosis, non-spatial working memory and anxiety in rats. | Experimental brain research 20100401 |
| Sorafenib inhibits the shedding of major histocompatibility complex class I-related chain A on hepatocellular carcinoma cells by down-regulating a disintegrin and metalloproteinase 9. | Hepatology (Baltimore, Md.) 20100401 |
| Safety of transarterial chemoembolization plus sorafenib combination treatment in unresectable hepatocellular carcinoma. | Scandinavian journal of gastroenterology 20100401 |
| A phase II study of sorafenib in advanced uterine carcinoma/carcinosarcoma: a trial of the Chicago, PMH, and California Phase II Consortia. | Gynecologic oncology 20100401 |
| Synthesis of nicotinamide-based molecularly imprinted microspheres and in vitro controlled release studies. | Drug delivery 20100401 |
| Activity of a multitargeted chemo-switch regimen (sorafenib, gemcitabine, and metronomic capecitabine) in metastatic renal-cell carcinoma: a phase 2 study (SOGUG-02-06). | The Lancet. Oncology 20100401 |
| Vascular endothelial growth factor targeted therapy in the perioperative setting: implications for patient care. | The Lancet. Oncology 20100401 |
| NAD+ auxotrophy is bacteriocidal for the tubercle bacilli. | Molecular microbiology 20100401 |
| Vitamin B3, the nicotinamide adenine dinucleotides and aging. | Mechanisms of ageing and development 20100401 |
| Photoprotective effects of nicotinamide. | Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20100401 |
| Metronomic chemotherapy for renal cancer in the landscape of targeted therapy. | The Lancet. Oncology 20100401 |
| Sorafenib induces growth arrest and apoptosis of human glioblastoma cells through the dephosphorylation of signal transducers and activators of transcription 3. | Molecular cancer therapeutics 20100401 |
| Injection order effects on efficacy of calcium chloride and sodium tripolyphosphate in controlling the pink color defect in uncured, intact turkey breast. | Meat science 20100401 |
| Sunitinib, sorafenib, temsirolimus or bevacizumab in the treatment of metastatic renal cell carcinoma: a review of health economic evaluations. | Journal of chemotherapy (Florence, Italy) 20100401 |
| Niaprazine may improve some symptoms of attention-deficit hyperactivity disorder. | Minerva pediatrica 20100401 |
| [Efficacy of cytoflavin in the treatment of vertebrobasilar insufficiency]. | Eksperimental'naia i klinicheskaia farmakologiia 20100401 |
| [Effect of 1-methylnicotinamide on prooxidant-antioxidant balance parameters in rats during hepatic ischemia-reperfusion]. | Eksperimental'naia i klinicheskaia farmakologiia 20100401 |
| [Diagnosis and treatment of bone metastasis of renal cancer: an expert consensus statement (2008 version)]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20100401 |
| Neoadjuvant clinical trial with sorafenib for patients with stage II or higher renal cell carcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100320 |
| Rlip76 transports sunitinib and sorafenib and mediates drug resistance in kidney cancer. | International journal of cancer 20100315 |
| Efficacy of targeted therapy in patients with renal cell carcinoma with pre-existing or new bone metastases. | Journal of cancer research and clinical oncology 20100301 |
| Wernicke encephalopathy complicating hyperemesis gravidarum: a case report. | European journal of obstetrics, gynecology, and reproductive biology 20100301 |
| Mechanisms of myocyte cytotoxicity induced by the multikinase inhibitor sorafenib. | Cardiovascular toxicology 20100301 |
| [Impact of immunotherapy in metastatic kidney cancer in Germany after introduction of new target therapy--results of a telephone survey of the German Society of Immuno- and Targeted Therapy (DGFIT)]. | Aktuelle Urologie 20100301 |
| Hepatitis C virus infection reduces hepatocellular polarity in a vascular endothelial growth factor-dependent manner. | Gastroenterology 20100301 |
| Inhibition of SIRT1 deacetylase suppresses estrogen receptor signaling. | Carcinogenesis 20100301 |
| Functional and biochemical evidence indicating beneficial effect of Melatonin and Nicotinamide alone and in combination in experimental diabetic neuropathy. | Neuropharmacology 20100301 |
| A dosing/cross-development study of the multikinase inhibitor sorafenib in patients with pulmonary arterial hypertension. | Clinical pharmacology and therapeutics 20100301 |
| Involvement of histamine and histamine H2 receptors in nicotinamide-induced differentiation of human amniotic epithelial cells into insulin-producing cells. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20100301 |
| Decrease in expression of histamine H2 receptors by human amniotic epithelial cells during differentiation into pancreatic beta-like cells. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20100301 |
| Sorafenib improves the survival of patients with advanced hepatocellular carcinoma: a meta-analysis of randomized trials. | Anti-cancer drugs 20100301 |
| Complete remission in a patient with multifocal metastatic cutaneous angiosarcoma with a combination of paclitaxel and sorafenib. | The British journal of dermatology 20100301 |
| Maintenance therapy in acute myeloid leukemia revisited: will new agents rekindle an old interest? | Current opinion in hematology 20100301 |
| The multikinase inhibitor Sorafenib induces apoptosis and sensitises endometrial cancer cells to TRAIL by different mechanisms. | European journal of cancer (Oxford, England : 1990) 20100301 |
| Toxicity of sorafenib: clinical and molecular aspects. | Expert opinion on drug safety 20100301 |
| Promotion of beta-cell differentiation by the alkaloid conophylline in porcine pancreatic endocrine cells. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20100301 |
| Safety and efficacy results of the advanced renal cell carcinoma sorafenib expanded access program in North America. | Cancer 20100301 |
| Histone deacetylase inhibitors suppress inflammatory activation of rheumatoid arthritis patient synovial macrophages and tissue. | Journal of immunology (Baltimore, Md. : 1950) 20100301 |
| Dissipation and residues of boscalid in strawberries and soils. | Bulletin of environmental contamination and toxicology 20100301 |
| Inhibition of MEK/ERK1/2 sensitizes lymphoma cells to sorafenib-induced apoptosis. | Leukemia research 20100301 |
| Discovery and initial SAR of pyrimidin-4-yl-1H-imidazole derivatives with antiproliferative activity against melanoma cell lines. | Bioorganic & medicinal chemistry letters 20100301 |
| High-contrast PET of melanoma using (18)F-MEL050, a selective probe for melanin with predominantly renal clearance. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100301 |
| Comparative profiling of the novel epothilone, sagopilone, in xenografts derived from primary non-small cell lung cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20100301 |
| [Use of sorafenib in patients with hepatocellular or renal carcinoma]. | Gastroenterologie clinique et biologique 20100301 |
| Phase I combination of sorafenib and erlotinib therapy in solid tumors: safety, pharmacokinetic, and pharmacodynamic evaluation from an expansion cohort. | Molecular cancer therapeutics 20100301 |
| Sorafenib inhibits STAT3 activation to enhance TRAIL-mediated apoptosis in human pancreatic cancer cells. | Molecular cancer therapeutics 20100301 |
| Raf inhibitors as therapeutic agents against neurodegenerative diseases. | CNS & neurological disorders drug targets 20100301 |
| Impact of metronomic UFT/cyclophosphamide chemotherapy and antiangiogenic drug assessed in a new preclinical model of locally advanced orthotopic hepatocellular carcinoma. | Neoplasia (New York, N.Y.) 20100301 |
| Complete remission of unresectable hepatocellular carcinoma treated with reduced dose of sorafenib: a case report. | Targeted oncology 20100301 |
| [Chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20100301 |
| The 2008 Okuda lecture: Management of hepatocellular carcinoma: from surveillance to molecular targeted therapy. | Journal of gastroenterology and hepatology 20100301 |
| Combined treatment of tetrahydrocurcumin and chlorogenic acid exerts potential antihyperglycemic effect on streptozotocin-nicotinamide-induced diabetic rats. | General physiology and biophysics 20100301 |
| A randomized, controlled comparative study of the wrinkle reduction benefits of a cosmetic niacinamide/peptide/retinyl propionate product regimen vs. a prescription 0.02% tretinoin product regimen. | The British journal of dermatology 20100301 |
| Nia1 and Nia2 are involved in exogenous salicylic acid-induced nitric oxide generation and stomatal closure in Arabidopsis. | Journal of integrative plant biology 20100301 |
| Molecular therapy of pancreatic cancer. | Minerva endocrinologica 20100301 |
| [Cardioprotective effect of cytoflavine on a model of doxorubicin-induced cardiomyopathy]. | Eksperimental'naia i klinicheskaia farmakologiia 20100301 |
| Preoperative induction with sorafenib pathologically downstaged advanced renal cell carcinoma: a case report. | International journal of urology : official journal of the Japanese Urological Association 20100301 |
| Sorafenib, a dual Raf kinase/vascular endothelial growth factor receptor inhibitor has significant anti-myeloma activity and synergizes with common anti-myeloma drugs. | Oncogene 20100225 |
| [Chronic nicotinamide overload and type 2 diabetes]. | Sheng li xue bao : [Acta physiologica Sinica] 20100225 |
| Identification of bona fide esophageal adenocarcinoma cell lines. | Journal of the National Cancer Institute 20100224 |
| Verification and unmasking of widely used human esophageal adenocarcinoma cell lines. | Journal of the National Cancer Institute 20100224 |
| Association of skeletal muscle wasting with treatment with sorafenib in patients with advanced renal cell carcinoma: results from a placebo-controlled study. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100220 |
| Characterization of Streptococcus pyogenes beta-NAD+ glycohydrolase: re-evaluation of enzymatic properties associated with pathogenesis. | The Journal of biological chemistry 20100219 |
| FLT3-mutant allelic burden and clinical status are predictive of response to FLT3 inhibitors in AML. | Blood 20100218 |
| Review article: the management of hepatocellular carcinoma. | Alimentary pharmacology & therapeutics 20100215 |
| Design of novel nicotinamides as potent and selective monoamine oxidase a inhibitors. | Bioorganic & medicinal chemistry 20100215 |
| Sorafenib-associated remission of psoriasis in hypernephroma: case report. | Dermatology online journal 20100215 |
| Nicotinamide alleviates indomethacin-induced gastric ulcers: a novel antiulcer agent. | European journal of pharmacology 20100210 |
| Combination therapy: intermittent sorafenib with bevacizumab yields activity and decreased toxicity. | British journal of cancer 20100202 |
| Statins potentiate cytostatic/cytotoxic activity of sorafenib but not sunitinib against tumor cell lines in vitro. | Cancer letters 20100201 |
| Relationship between phosphodiesterase type 4 inhibition and anti-inflammatory activity of CI-1044 in rat airways. | Fundamental & clinical pharmacology 20100201 |
| The tyrosine kinase inhibitor sorafenib decreases cell number and induces apoptosis in a canine osteosarcoma cell line. | Research in veterinary science 20100201 |
| Glucose-regulated protein 78 is a novel contributor to acquisition of resistance to sorafenib in hepatocellular carcinoma. | Annals of surgical oncology 20100201 |
| Reduction in the appearance of facial hyperpigmentation after use of moisturizers with a combination of topical niacinamide and N-acetyl glucosamine: results of a randomized, double-blind, vehicle-controlled trial. | The British journal of dermatology 20100201 |
| Interstitial pneumonia probably associated with sorafenib treatment: An alert of an adverse event. | Lung cancer (Amsterdam, Netherlands) 20100201 |
| VEGFR TKI 'resistance' or transient clinical insensitivity to VEGFR TKI in metastatic renal cell carcinoma. | Annals of oncology : official journal of the European Society for Medical Oncology 20100201 |
| Radiation recall dermatitis triggered by multi-targeted tyrosine kinase inhibitors: sunitinib and sorafenib. | Anti-cancer drugs 20100201 |
| Sorafenib - a small molecule with big promise? | Leukemia & lymphoma 20100201 |
| Re: Sequential sorafenib and sunitinib for renal cell carcinoma M. P. Sablin, S. Negrier, A. Ravaud, S. Oudard, C. Balleyguier, J. Gautier, C. Celier, J. Medioni and B. Escudier J Urol 2009; 182: 29-34. | The Journal of urology 20100201 |
| Breast cancer resistance protein and P-glycoprotein limit sorafenib brain accumulation. | Molecular cancer therapeutics 20100201 |
| Targeting vascular endothelial growth factor receptor in thyroid cancer: the intracellular and extracellular implications. | Clinical cancer research : an official journal of the American Association for Cancer Research 20100201 |
| Hepatitis C virus proteins modulate microRNA expression and chemosensitivity in malignant hepatocytes. | Clinical cancer research : an official journal of the American Association for Cancer Research 20100201 |
| A randomized phase I clinical and biologic study of two schedules of sorafenib in patients with myelodysplastic syndrome or acute myeloid leukemia: a NCIC (National Cancer Institute of Canada) Clinical Trials Group Study. | Leukemia & lymphoma 20100201 |
| Anti-vascular endothelial growth factor therapies and cardiovascular toxicity: what are the important clinical markers to target? | The oncologist 20100201 |
| Sorafenib therapy for hepatocellular carcinoma in an HIV-HCV coinfected patient: a case report. | The oncologist 20100201 |
| Risk of bleeding not increased by sorafenib or sunitinib. | The Lancet. Oncology 20100201 |
| Diabetes mellitus: channeling care through cellular discovery. | Current neurovascular research 20100201 |
| Current strategy for staging and treatment: the BCLC update and future prospects. | Seminars in liver disease 20100201 |
| Influence of manipulating hypoxia in solid tumors on the radiation dose-rate effect in vivo, with reference to that in the quiescent cell population. | Japanese journal of radiology 20100201 |
| Sorafenib-induced psoriasiform eruption in a patient with metastatic thyroid carcinoma. | Journal of drugs in dermatology : JDD 20100201 |
| Prognostic factors in patients treated with VEGF-targeted therapies. | Clinical advances in hematology & oncology : H&O 20100201 |
| [Treatment of locally advanced renal tumors]. | Actas urologicas espanolas 20100201 |
| Hepatocellular carcinoma--what's new? | Journal of visceral surgery 20100201 |
| CD133+ circulating haematopoietic progenitor cells predict for response to sorafenib plus erlotinib in non-small cell lung cancer patients. | British journal of cancer 20100119 |
| Development of molecularly targeted therapies in hepatocellular carcinoma: where do we go now? | Clinical cancer research : an official journal of the American Association for Cancer Research 20100115 |
| Sorafenib-induced bilateral osteonecrosis of femoral heads. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100110 |
| Elucidating the structure-activity relationships of the vasorelaxation and antioxidation properties of thionicotinic acid derivatives. | Molecules (Basel, Switzerland) 20100106 |
| Sorafenib in patients with advanced biliary tract carcinoma: a phase II trial. | British journal of cancer 20100105 |
| Safety and efficacy of sorafenib in patients with castrate resistant prostate cancer: a Phase II study. | Urologic oncology 20100101 |
| Complete remission achieved with angiogenic therapy in metastatic renal cell carcinoma including surgical intervention. | Urologic oncology 20100101 |
| Construction of adiponectin-encoding plasmid DNA and gene therapy of non-obese type 2 diabetes mellitus. | Journal of drug targeting 20100101 |
| Sorafenib induces partial response in metastatic medullary thyroid carcinoma. | Acta oncologica (Stockholm, Sweden) 20100101 |
| Rapid response to therapy of neurocutaneous melanosis with leptomeningeal melanoma. | Pediatric blood & cancer 20100101 |
| Nicotinamide glycolates antagonize CXCR2 activity through an intracellular mechanism. | The Journal of pharmacology and experimental therapeutics 20100101 |
| Sorafenib as a feasible therapeutic option in haemophiliacs with hepatocellular carcinoma. | Haemophilia : the official journal of the World Federation of Hemophilia 20100101 |
| Cost-effectiveness of sorafenib for second-line treatment of advanced renal cell carcinoma. | Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20100101 |
| Regional differential effects of the novel histamine H3 receptor antagonist 6-[(3-cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-N-methyl-3-pyridinecarboxamide hydrochloride (GSK189254) on histamine release in the central nervous system of freely moving rats. | The Journal of pharmacology and experimental therapeutics 20100101 |
| 1-methylnicotinamide (MNA) in prevention of diabetes-associated brain disorders. | Neurochemistry international 20100101 |
| Acute aortic dissection during sorafenib-containing therapy. | Annals of oncology : official journal of the European Society for Medical Oncology 20100101 |
| It takes two to tango: combinations of conventional cytotoxics with compounds targeting the vascular endothelial growth factor-vascular endothelial growth factor receptor pathway in patients with solid malignancies. | Cancer science 20100101 |
| Upfront, randomized, phase 2 trial of sorafenib versus sorafenib and low-dose interferon alfa in patients with advanced renal cell carcinoma: clinical and biomarker analysis. | Cancer 20100101 |
| Use of sorafenib in patients with hepatocellular carcinoma before liver transplantation: a cost-benefit analysis while awaiting data on sorafenib safety. | Hepatology (Baltimore, Md.) 20100101 |
| Nephrotic syndrome caused by the angiogenesis inhibitor sorafenib. | Annals of oncology : official journal of the European Society for Medical Oncology 20100101 |
| Where does the combination of sorafenib and interferon in renal cell carcinoma stand? | Cancer 20100101 |
| Synthesis and antiproliferative activity of pyrrolo[3,2-b]pyridine derivatives against melanoma. | Bioorganic & medicinal chemistry letters 20100101 |
| About tyrosine kinase inhibitors (TKIs) in prostate cancer: where do we go from here? | Annals of oncology : official journal of the European Society for Medical Oncology 20100101 |
| AZD6244 enhances the anti-tumor activity of sorafenib in ectopic and orthotopic models of human hepatocellular carcinoma (HCC). | Journal of hepatology 20100101 |
| Evidence-based urology in practice: when to believe a subgroup analysis? | BJU international 20100101 |
| Pyridine salvage and nicotinic acid conjugate synthesis in leaves of mangrove species. | Phytochemistry 20100101 |
| Synergistic interactions between sorafenib and bortezomib in hepatocellular carcinoma involve PP2A-dependent Akt inactivation. | Journal of hepatology 20100101 |
| Abnormalities of thyroid function in Japanese patients with metastatic renal cell carcinoma treated with sorafenib: a prospective evaluation. | Urologic oncology 20100101 |
| Ab initio studies of molecular structures, conformers and vibrational spectra of heterocyclic organics: I. Nicotinamide and its N-oxide. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20100101 |
| Platelet count less than SHARP: what does a case series reveal? | Expert opinion on drug safety 20100101 |
| Bevacizumab, sorafenib tosylate, sunitinib and temsirolimus for renal cell carcinoma: a systematic review and economic evaluation. | Health technology assessment (Winchester, England) 20100101 |
| Phase 1b study of motesanib, an oral angiogenesis inhibitor, in combination with carboplatin/paclitaxel and/or panitumumab for the treatment of advanced non-small cell lung cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20100101 |
| Evaluation of response in malignant tumors treated with the multitargeted tyrosine kinase inhibitor sorafenib: a multitechnique imaging assessment. | AJR. American journal of roentgenology 20100101 |
| Assessing tumor response and detecting recurrence in metastatic renal cell carcinoma on targeted therapy: importance of size and attenuation on contrast-enhanced CT. | AJR. American journal of roentgenology 20100101 |
| Lack of association between excretion of sorafenib in sweat and hand-foot skin reaction. | Pharmacotherapy 20100101 |
| Compounds in clinical Phase III and beyond. | Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20100101 |
| Multifaceted perspective of the waiting list for liver transplantation: the value of pharmacokinetic models. | Hepatology (Baltimore, Md.) 20100101 |
| Early skin toxicity as a predictive factor for tumor control in hepatocellular carcinoma patients treated with sorafenib. | The oncologist 20100101 |
| Comparison of the anti-allergic activity of Syk inhibitors with optimized Syk siRNAs in FcepsilonRI-activated RBL-2H3 basophilic cells. | Cellular immunology 20100101 |
| Inhibition of tumor angiogenesis by the matrix metalloproteinase-activated anthrax lethal toxin in an orthotopic model of anaplastic thyroid carcinoma. | Molecular cancer therapeutics 20100101 |
| Nicotinamide and neutrophilia. | Nature medicine 20100101 |
| Hepatocellular carcinoma: novel molecular approaches for diagnosis, prognosis, and therapy. | Annual review of medicine 20100101 |
| Sustained remission with the kinase inhibitor sorafenib in stage IV metastatic adrenocortical carcinoma. | Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20100101 |
| The effects of a daily facial lotion containing vitamins B3 and E and provitamin B5 on the facial skin of Indian women: a randomized, double-blind trial. | Indian journal of dermatology, venereology and leprology 20100101 |
| Sorafenib. | Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20100101 |
| Managing adverse events associated with sorafenib in renal cell carcinoma. | British journal of nursing (Mark Allen Publishing) 20100101 |
| Progress in the management of advanced renal cell carcinoma (RCC). | Aktuelle Urologie 20100101 |
| A retroperitoneal mass with elevated alpha-1-fetoprotein: not always a testicular carcinoma. | The Netherlands journal of medicine 20100101 |
| The mitochondria-independent cytotoxic effect of nelfinavir on leukemia cells can be enhanced by sorafenib-mediated mcl-1 downregulation and mitochondrial membrane destabilization. | Molecular cancer 20100101 |
| [Renal cell carcinoma]. | Gan to kagaku ryoho. Cancer & chemotherapy 20100101 |
| Maintenance of Sorafenib following combined therapy of three-dimensional conformal radiation therapy/intensity-modulated radiation therapy and transcatheter arterial chemoembolization in patients with locally advanced hepatocellular carcinoma: a phase I/II study. | Radiation oncology (London, England) 20100101 |
| Choroidal metastasis of renal cell carcinoma: a case report. | Japanese journal of ophthalmology 20100101 |
| [Current aspects of second-line and sequence therapy of metastatic renal cell carcinoma]. | Onkologie 20100101 |
| SIRT1 negatively regulates the mammalian target of rapamycin. | PloS one 20100101 |
| Regeneration of nicotinamide coenzymes: principles and applications for the synthesis of chiral compounds. | Advances in biochemical engineering/biotechnology 20100101 |
| [Antioxidant activity of cytoflavin in experimental diffuse purulent peritonitis]. | Eksperimental'naia i klinicheskaia farmakologiia 20100101 |
| Receptor tyrosine kinase inhibitors in rodent pulmonary hypertension. | Advances in experimental medicine and biology 20100101 |
| Markedly effective local control of hepatocellular carcinoma with a poor prognosis by combined multimodal therapy with sorafenib as a neoadjuvant approach. | Gastroenterologie clinique et biologique 20100101 |
| [Treatment of advanced hepatocellular carcinoma]. | Gastroenterologia y hepatologia 20100101 |
| New therapeutic strategies for renal cell carcinoma. | Urologic nursing 20100101 |
| [Simultaneous determination of five water-soluble vitamins in human serum by high performance liquid chromatography]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20100101 |
| [Targeted therapies in hepatocellular carcinoma]. | Presse medicale (Paris, France : 1983) 20100101 |
| Evaluation of multiple targeted agents as potential therapies for hepatocellular carcinoma (HCC). Foreword. | Current problems in cancer 20100101 |
| Current problems with systemic treatment of advanced hepatocellular cancer. | Current problems in cancer 20100101 |
| [Renal cell carcinoma management and therapies in 2010]. | Bulletin du cancer 20100101 |
| [Angiogenesis inhibition: review of the activity of sorafenib, sunitinib and bevacizumab]. | Bulletin du cancer 20100101 |
| [Targeted therapies: sequential and combined treatments]. | Bulletin du cancer 20100101 |
| [Management of side effects associated with antiangiogenic treatment in renal cell carcinoma]. | Bulletin du cancer 20100101 |
| [Advanced renal carcinomas with special situations. How to treat them?]. | Bulletin du cancer 20100101 |
| A single-institute experience with sorafenib in untreated and previously treated patients with advanced hepatocellular carcinoma. | Oncology 20100101 |
| [Determination of alpha-arbutin, beta-arbutin and niacinamide in cosmetics by high performance liquid chromatography]. | Se pu = Chinese journal of chromatography 20100101 |
| [Interests in angiogenesis inhibitor drugs approved for the treatment of cancers]. | Therapie 20100101 |
| Sorafenib downregulates ERK/Akt and STAT3 survival pathways and induces apoptosis in a human neuroblastoma cell line. | International journal of clinical and experimental pathology 20100101 |
| Nicotinamide prevents ultraviolet radiation-induced cellular energy loss. | Photochemistry and photobiology 20100101 |
| Interferon-gamma elevates nicotinamide N-methyltransferase activity and nicotinamide level in human glioma cells. | Journal of nutritional science and vitaminology 20100101 |
| Hepatoid adenocarcinoma - review of the literature illustrated by a rare case originating in the peritoneal cavity. | Onkologie 20100101 |
| [Efficacy of the complex drug cytoflavin in the treatment of consequences of mild brain injury]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101 |
| A patient with advanced hepatocellular carcinoma treated with sorafenib tosylate showed massive tumor lysis with avoidance of tumor lysis syndrome. | Internal medicine (Tokyo, Japan) 20100101 |
| [Correction of metabolic disturbances in cancer patients in the early postanesthesia period]. | Khirurgiia 20100101 |
| [Cytoflavin in total intravenous anesthesia]. | Vestnik khirurgii imeni I. I. Grekova 20100101 |
| [Perspectives of treatment of patients with ischemic stroke: the place and the role of cytoflavin]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101 |
| [Efficacy of cytoflavin in therapy of encephalophathy in patients with neuroinfection]. | Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20100101 |
| The efficacy of nicotinamide gel 4% as an adjuvant therapy in the treatment of cutaneous erosions of pemphigus vulgaris. | Dermatologic therapy 20100101 |
| [Efficacy of cytoflavin in the treatment of chronic cerebral ischemia]. | Klinicheskaia meditsina 20100101 |
| Hypertension and hand-foot skin reactions related to VEGFR2 genotype and improved clinical outcome following bevacizumab and sorafenib. | Journal of experimental & clinical cancer research : CR 20100101 |
| Nicotinamide N-methyltransferase (NNMT) and 1-methylnicotinamide (MNA) in experimental hepatitis induced by concanavalin A in the mouse. | Pharmacological reports : PR 20100101 |
| Motesanib inhibits Kit mutations associated with gastrointestinal stromal tumors. | Journal of experimental & clinical cancer research : CR 20100101 |
| Response to sorafenib in a patient with metastatic xp11 translocation renal cell carcinoma. | Clinical drug investigation 20100101 |
| Targeted treatment for metastatic renal cell carcinoma and immune regulation. | Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20100101 |
| Ecthyma-gangrenosum-like bullous pemphigoid. | Dermatology (Basel, Switzerland) 20100101 |
| Evolution of an adenocarcinoma in response to selection by targeted kinase inhibitors. | Genome biology 20100101 |
| Sorafenib after combination therapy with gemcitabine plus doxorubicine in patients with sarcomatoid renal cell carcinoma: a prospective evaluation. | European journal of medical research 20100101 |
| Effective treatment of advanced cholangiocarcinoma by hepatic arterial infusion chemotherapy combination with sorafenib: one case report from China. | Hepato-gastroenterology 20100101 |
| Synergistic cytotoxicity and molecular interaction on drug targets of sorafenib and gemcitabine in human pancreas cancer cells. | Chemotherapy 20100101 |
| Sustained delivery of nicotinamide limits cortical injury and improves functional recovery following traumatic brain injury. | Oxidative medicine and cellular longevity 20100101 |
| Does basal cell carcinoma belong to the spectrum of sorafenib-induced epithelial skin cancers? | Dermatology (Basel, Switzerland) 20100101 |
| Identification and characterization of novel oncogenes in chronic eosinophilic leukemia and T-cell acute lymphoblastic leukemia. | Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie 20100101 |
| Safety and efficacy of sorafenib in elderly patients treated in the North American advanced renal cell carcinoma sorafenib expanded access program. | Oncology 20100101 |
| Comparative study of the binding characteristics to and inhibitory potencies towards PARP and in vivo antidiabetogenic potencies of taurine, 3-aminobenzamide and nicotinamide. | Journal of biomedical science 20100101 |
| [Nexavar clinical registry]. | Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti 20100101 |
| A structure-based approach for mapping adverse drug reactions to the perturbation of underlying biological pathways. | PloS one 20100101 |
| I-kappa-kinase-2 (IKK-2) inhibition potentiates vincristine cytotoxicity in non-Hodgkin's lymphoma. | Molecular cancer 20100101 |
| [Current approaches to treating acute gastroduodenal ulcer bleedings]. | Khirurgiia 20100101 |
| [Effect of early correction of energy and free-radical homeostasis on the clinical-morphological presentation of cerebral infarction]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101 |
| Effect of nicotinamide and its two derivatives on the generation of reactive oxygen species in human monocytes cooperating with platelets. | Acta poloniae pharmaceutica 20100101 |
| [Therapeutic efficiency of cytoflavine solution for infusion in emergency conditions]. | Klinicheskaia meditsina 20100101 |
| Sorafenib treatment in 13 patients with acute myeloid leukemia and activating FLT3 mutations in combination with chemotherapy or as monotherapy. | Acta haematologica 20100101 |
| A long-lasting response to sorafenib treatment in an advanced hepatocellular carcinoma patient. | International journal of immunopathology and pharmacology 20100101 |
| The multikinase inhibitor Sorafenib displays significant antiproliferative effects and induces apoptosis via caspase 3, 7 and PARP in B- and T-lymphoblastic cells. | BMC cancer 20100101 |
| Hyperkeratotic eczema of the nipple and areola associated with sorafenib treatment. | European journal of dermatology : EJD 20100101 |
| Feasibility and activity of sorafenib and sunitinib in advanced penile cancer: a preliminary report. | Urologia internationalis 20100101 |
| Tumor lysis syndrome after sorafenib for hepatocellular carcinoma: a case report. | Hepato-gastroenterology 20100101 |
| Treatment with sorafenib in advanced thyroid cancer - a case report. | Endokrynologia Polska 20100101 |
| [Hand-foot syndrome after administration of tyrosinkinase inhibitors]. | Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti 20100101 |
| Antiangiogenic therapy for breast cancer. | Breast cancer research : BCR 20100101 |
| Safety and feasibility of using sorafenib in recurrent hepatocellular carcinoma after orthotopic liver transplantation. | Oncology 20100101 |
| Sunitinib in patients with advanced hepatocellular carcinoma after progression under sorafenib treatment. | Oncology 20100101 |
| Cosmeceutical testing: ethical and scientific issues. | Indian journal of dermatology, venereology and leprology 20100101 |
| [Improvement of speech discrimination with cytoflavin in patients with chronic sensorineural deafness]. | Vestnik otorinolaringologii 20100101 |
| [The use of cytoflavin in combined neurometabolic therapy of acute cerebral insufficiency associated with acute poisoning with neurotropic poisons]. | Klinicheskaia meditsina 20100101 |
| Treatment of intermediate/advanced hepatocellular carcinoma in the clinic: how can outcomes be improved? | The oncologist 20100101 |
| [Cytoflavin in polychemotherapy of breast cancer]. | Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20100101 |
| Light-induced photoreceptor and RPE degeneration involve zinc toxicity and are attenuated by pyruvate, nicotinamide, or cyclic light. | Molecular vision 20100101 |
| [Efficacy of cytoflavin in the treatment of burns patients with toxic and post-hypoxic encephalopathy]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101 |
| RAF kinase activity regulates neuroepithelial cell proliferation and neuronal progenitor cell differentiation during early inner ear development. | PloS one 20100101 |
| A phase II trial of sorafenib in metastatic melanoma with tissue correlates. | PloS one 20100101 |
| Is it possible to optimize the use of targeted therapies in the treatment of renal cell carcinoma? | Tumori 20100101 |
| [Efficacy of cytoflavin in patients in the acute ischemic stroke]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101 |
| [Economic evaluation of targeted biologic therapy in metastatic renal cell carcinoma]. | Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti 20100101 |
| [Experimental study on cytoflavin pharmacological correction of cyclophosphamide-induced toxic affections of the liver and kidneys]. | Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20100101 |
| Cryopreservation of chick islets. | Cryo letters 20100101 |
| [Antioxidant therapy in discirculatory encephalopathy]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101 |
| The effects of hypertonic saline and nicotinamide on sensorimotor and cognitive function following cortical contusion injury in the rat. | Brain research 20091222 |
| Beneficial effects of thymoquinone on hepatic key enzymes in streptozotocin-nicotinamide induced diabetic rats. | Life sciences 20091216 |
| Alveolar rhabdomyosarcoma of the extremity and nodal metastasis: Is the in-transit lymphatic system at risk? | Pediatric blood & cancer 20091215 |
| The kinase inhibitors sunitinib and sorafenib differentially affect NK cell antitumor reactivity in vitro. | Journal of immunology (Baltimore, Md. : 1950) 20091215 |
| Identification of Isn1 and Sdt1 as glucose- and vitamin-regulated nicotinamide mononucleotide and nicotinic acid mononucleotide [corrected] 5'-nucleotidases responsible for production of nicotinamide riboside and nicotinic acid riboside. | The Journal of biological chemistry 20091211 |
| Nicotinamide overload may play a role in the development of type 2 diabetes. | World journal of gastroenterology 20091207 |
| UGT1A1 polymorphism and hyperbilirubinemia in a patient who received sorafenib. | Cancer chemotherapy and pharmacology 20091201 |
| Rectal fistulae resulting from treatment with sorafenib and bevacizumab. | Gastrointestinal endoscopy 20091201 |
| Quality of life in patients with metastatic renal cell carcinoma: the importance of patient-reported outcomes. | Cancer treatment reviews 20091201 |
| New aspects of an anti-tumour drug: sorafenib efficiently inhibits HCV replication. | Gut 20091201 |
| SIRT1 regulates Tat-induced HIV-1 transactivation through activating AMP-activated protein kinase. | Virus research 20091201 |
| Clinical pharmacokinetics of tyrosine kinase inhibitors. | Cancer treatment reviews 20091201 |
| Beneficial effects of sorafenib on tumor progression, but not on radioiodine uptake, in patients with differentiated thyroid carcinoma. | European journal of endocrinology 20091201 |
| Topical nicotinamide modulates cellular energy metabolism and provides broad-spectrum protection against ultraviolet radiation-induced immunosuppression in humans. | The British journal of dermatology 20091201 |
| Profiles of the biosynthesis and metabolism of pyridine nucleotides in potatoes (Solanum tuberosum L.). | Planta 20091201 |
| Sorafenib inhibits signal transducer and activator of transcription-3 signaling in cholangiocarcinoma cells by activating the phosphatase shatterproof 2. | Hepatology (Baltimore, Md.) 20091201 |
| Prognostic factors for overall survival in patients with metastatic renal cell carcinoma treated with vascular endothelial growth factor-targeted agents: results from a large, multicenter study. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20091201 |
| Interaction of nicotinamide and picolinamide with phosphatidylcholine and phosphatidylethanolamine membranes: a combined approach using dipole potential measurements and quantum chemical calculations. | Biochimica et biophysica acta 20091201 |
| Sorafenib-induced hepatic encephalopathy. | The Annals of pharmacotherapy 20091201 |
| Sorafenib-induced hand-foot skin reaction: a Koebner phenomenon? | Targeted oncology 20091201 |
| 11C-GSK189254: a selective radioligand for in vivo central nervous system imaging of histamine H3 receptors by PET. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20091201 |
| Elevated International Normalized Ratio associated with concurrent use of sorafenib and warfarin. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20091201 |
| Tyrosine kinase inhibitors and the thyroid. | Best practice & research. Clinical endocrinology & metabolism 20091201 |
| Sorafenib-induced acute myocardial infarction due to coronary artery spasm. | Journal of cardiology 20091201 |
| Metastatic renal cell carcinoma: current standards of care. | Clinical journal of oncology nursing 20091201 |
| Management of vascular endothelial growth factor and multikinase inhibitor side effects. | Clinical journal of oncology nursing 20091201 |
| Health policy: The UK 'postcode lottery' in renal cell carcinoma. | Nature reviews. Urology 20091201 |
| [Rosacea 2009 : new advances in pathophysiology, clinical staging and therapeutic strategies]. | Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20091201 |
| Reduction in the appearance of facial hyperpigmentation by topical N-undecyl-10-enoyl-L-phenylalanine and its combination with niacinamide. | Journal of cosmetic dermatology 20091201 |
| [Sorafenib-induced multiple eruptive keratoacanthomas]. | Annales de dermatologie et de venereologie 20091201 |
| Apparent remission of a solitary metastatic pulmonary lesion in a liver transplant recipient treated with sorafenib. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20091201 |
| [Targeting KRAS pathway in NSCLC therapy]. | Bulletin du cancer 20091201 |
| Sorafenib inhibits ERK1/2 and MCL-1(L) phosphorylation levels resulting in caspase-independent cell death in malignant pleural mesothelioma. | Cancer biology & therapy 20091201 |
| Tyrosine kinase inhibitor-induced macrocytosis. | Anticancer research 20091201 |
| Hepatocellular carcinoma: the search for innovative adjuvant therapies. | Oncology (Williston Park, N.Y.) 20091201 |
| Targeted molecular therapies in thyroid carcinoma. | Arquivos brasileiros de endocrinologia e metabologia 20091201 |
| Highlights from the Eigth International Kidney Cancer Symposium. | Clinical advances in hematology & oncology : H&O 20091201 |
| Effect of nicotinamide on early graft failure following intraportal islet transplantation. | Experimental & molecular medicine 20091130 |
| Baying for a flexible drug price. | Lancet (London, England) 20091128 |
| Identification of an iron-sulfur cluster that modulates the enzymatic activity in NarE, a Neisseria meningitidis ADP-ribosyltransferase. | The Journal of biological chemistry 20091127 |
| NICE rules that drug used in advanced liver cancer is not cost effective for the NHS. | BMJ (Clinical research ed.) 20091123 |
| Myelosuppression and kinase selectivity of multikinase angiogenesis inhibitors. | British journal of cancer 20091117 |
| Phase I trial of a combination of the multikinase inhibitor sorafenib and the farnesyltransferase inhibitor tipifarnib in advanced malignancies. | Clinical cancer research : an official journal of the American Association for Cancer Research 20091115 |
| MicroRNA-122 inhibits tumorigenic properties of hepatocellular carcinoma cells and sensitizes these cells to sorafenib. | The Journal of biological chemistry 20091113 |
| C-Raf inhibits MAPK activation and transformation by B-Raf(V600E). | Molecular cell 20091113 |
| Efficacy of a novel, orally active GSK-3 inhibitor 6-Methyl-N-[3-[[3-(1-methylethoxy)propyl]carbamoyl]-1H-pyrazol-4-yl]pyridine-3-carboxamide in tau transgenic mice. | Brain research 20091103 |
| Effect of soft segment crystallization and hard segment physical crosslink on shape memory function in antibacterial segmented polyurethane ionomers. | Acta biomaterialia 20091101 |
| Cutaneous adverse effects in patients treated with the multitargeted kinase inhibitors sorafenib and sunitinib. | The British journal of dermatology 20091101 |
| A continuous microplate assay for sirtuins and nicotinamide-producing enzymes. | Analytical biochemistry 20091101 |
| H3 receptor antagonism enhances NCAM PSA-mediated plasticity and improves memory consolidation in odor discrimination and delayed match-to-position paradigms. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20091101 |
| Eruptive keratoacanthoma-type squamous cell carcinomas in patients taking sorafenib for the treatment of solid tumors. | Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20091101 |
| Mechanistic studies on the effects of nicotinamide on megakaryocytic polyploidization and the roles of NAD+ levels and SIRT inhibition. | Experimental hematology 20091101 |
| Sorafenib attenuates the portal hypertensive syndrome in partial portal vein ligated rats. | Journal of hepatology 20091101 |
| Nicotinamide inhibits Propionibacterium acnes-induced IL-8 production in keratinocytes through the NF-kappaB and MAPK pathways. | Journal of dermatological science 20091101 |
| Nicotinamidase modulation of NAD+ biosynthesis and nicotinamide levels separately affect reproductive development and cell survival in C. elegans. | Development (Cambridge, England) 20091101 |
| Therapy for metastatic RCC--questions remain. | Nature reviews. Urology 20091101 |
| An association of idiopathic chronic eosinophilic pneumonia with pemphigoid nodularis: a rare variant of bullous pemphigoid. | Archives of dermatology 20091101 |
| Everolimus: in advanced renal cell carcinoma. | Drugs 20091022 |
| Single-step conjugation of bioactive peptides to proteins via a self-contained succinimidyl bis-arylhydrazone. | Bioconjugate chemistry 20091021 |
| Design and synthesis of substituted nicotinamides as inhibitors of soluble epoxide hydrolase. | Bioorganic & medicinal chemistry letters 20091015 |
| Clinical trials of note. Sorafenib as adjuvant treatment in the prevention of disease recurrence in patients with hepatocellular carcinoma (HCC) (STORM). | Cancer 20091015 |
| Enzymatic synthesis and structural characterization of 13C, 15N-poly(ADP-ribose). | Journal of the American Chemical Society 20091014 |
| Plasmodium falciparum ferredoxin-NADP+ reductase His286 plays a dual role in NADP(H) binding and catalysis. | Biochemistry 20091013 |
| Comment on 'The Arabidopsis circadian clock incorporates a cADPR-based feedback loop'. | Science (New York, N.Y.) 20091009 |
| Structure-based optimization of arylamides as inhibitors of soluble epoxide hydrolase. | Journal of medicinal chemistry 20091008 |
| Activation of SIRT1 by resveratrol represses transcription of the gene for the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) by deacetylating hepatic nuclear factor 4alpha. | The Journal of biological chemistry 20091002 |
| A cross-over response to sequential use of sunitinib after sorafenib in a patient with metastatic renal cell carcinoma. | Clinical oncology (Royal College of Radiologists (Great Britain)) 20091001 |
| Effects of chronic treatment with a low dose of nicorandil on the function of the rat aorta during ageing. | Clinical and experimental pharmacology & physiology 20091001 |
| Erythema multiforme induced by sorafenib. | Clinical and experimental dermatology 20091001 |
| Down-regulation of HLA Class I and NKG2D ligands through a concerted action of MAPK and DNA methyltransferases in colorectal cancer cells. | International journal of cancer 20091001 |
| AC220 is a uniquely potent and selective inhibitor of FLT3 for the treatment of acute myeloid leukemia (AML). | Blood 20091001 |
| Use of metabolic control analysis to give quantitative information on control of lipid biosynthesis in the important oil crop, Elaeis guineensis (oilpalm). | The New phytologist 20091001 |
| Ras pathway activation in hepatocellular carcinoma and anti-tumoral effect of combined sorafenib and rapamycin in vivo. | Journal of hepatology 20091001 |
| Effect of the UK postcode lottery on survival of patients with metastatic renal cancer: an audit of outcomes in patients with metastatic renal cancer suitable for treatment with tyrosine kinase inhibitors. | Clinical oncology (Royal College of Radiologists (Great Britain)) 20091001 |
| Hepatocellular carcinoma: The beginning of a long journey. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20091001 |
| Identification of a cell-active non-peptide sirtuin inhibitor containing N-thioacetyl lysine. | Bioorganic & medicinal chemistry letters 20091001 |
| Complete resolution of leukemia cutis with sorafenib in an acute myeloid leukemia patient with FLT3-ITD mutation. | American journal of hematology 20091001 |
| An overview of small-molecule inhibitors of VEGFR signaling. | Nature reviews. Clinical oncology 20091001 |
| Radiolabeled humanized anti-CD3 monoclonal antibody visilizumab for imaging human T-lymphocytes. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20091001 |
| Risk of bleeding with vascular endothelial growth factor receptor tyrosine-kinase inhibitors sunitinib and sorafenib: a systematic review and meta-analysis of clinical trials. | The Lancet. Oncology 20091001 |
| Diffusion-weighted MRI of advanced hepatocellular carcinoma during sorafenib treatment: initial results. | AJR. American journal of roentgenology 20091001 |
| Sorafenib induces preferential apoptotic killing of a drug- and radio-resistant Hep G2 cells through a mitochondria-dependent oxidative stress mechanism. | Cancer biology & therapy 20091001 |
| Ambulatory monitoring detects sorafenib-induced blood pressure elevations on the first day of treatment. | Clinical cancer research : an official journal of the American Association for Cancer Research 20091001 |
| Interaction of the multikinase inhibitors sorafenib and sunitinib with solute carriers and ATP-binding cassette transporters. | Clinical cancer research : an official journal of the American Association for Cancer Research 20091001 |
| [Palmoplantar cutaneous reaction to sorafenib]. | Actas dermo-sifiliograficas 20091001 |
| Activation of cytosolic phospholipase A2alpha by epidermal growth factor (EGF) and phorbol ester in HeLa cells: different effects of inhibitors for EGF receptor, protein kinase C, Src, and C-Raf. | Journal of pharmacological sciences 20091001 |
| Rapid development of hypertension by sorafenib: toxicity or target? | Clinical cancer research : an official journal of the American Association for Cancer Research 20091001 |
| Sorafenib reveals efficacy in sequential treatment of metastatic renal cell cancer. | Expert review of anticancer therapy 20091001 |
| Multidisciplinary treatment including sorafenib stabilized the bone metastases of renal cell carcinoma in an immunosuppressed renal transplant recipient. | International journal of clinical oncology 20091001 |
| Inhibitory effect of glimepiride on nicotinamide-streptozotocin induced nuclear damages and sperm abnormality in diabetic Wistar rats. | Indian journal of experimental biology 20091001 |
| Development of a fluorescent-tagged kinase assay system for the detection and characterization of allosteric kinase inhibitors. | Journal of the American Chemical Society 20090923 |
| Sorafenib induced tumor lysis syndrome in an advanced hepatocellular carcinoma patient. | World journal of gastroenterology 20090921 |
| Phase II study of sorafenib in patients with sunitinib-refractory metastatic renal cell cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090920 |
| Phase II study of axitinib in sorafenib-refractory metastatic renal cell carcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090920 |
| Nicotinamide reduces dopamine in postnatal hypothalamus and causes dopamine-deficient phenotype. | Neuroscience letters 20090918 |
| Phase 2 trial of sorafenib in patients with advanced urothelial cancer: a trial of the Eastern Cooperative Oncology Group. | Cancer 20090915 |
| C-Raf is associated with disease progression and cell proliferation in a subset of melanomas. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090915 |
| Induction of Bim expression contributes to the antitumor synergy between sorafenib and mitogen-activated protein kinase/extracellular signal-regulated kinase kinase inhibitor CI-1040 in hepatocellular carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090915 |
| Phase II, multicenter, uncontrolled trial of single-agent sorafenib in patients with relapsed or refractory, advanced non-small-cell lung cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090910 |
| Long-term response in primary renal cancer to sequential antiangiogenic therapy. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090910 |
| Discovery of [18F]N-(2-(diethylamino)ethyl)-6-fluoronicotinamide: a melanoma positron emission tomography imaging radiotracer with high tumor to body contrast ratio and rapid renal clearance. | Journal of medicinal chemistry 20090910 |
| The vitamin nicotinamide: translating nutrition into clinical care. | Molecules (Basel, Switzerland) 20090909 |
| Mechanistic insights on the magnesium(II) ion-activated reduction of methyl benzoylformate with chelated NADH peptide beta-lactam models. | The Journal of organic chemistry 20090904 |
| Brain magnetic resonance imaging changes after sorafenib and sunitinib chemotherapy in patients with advanced renal cell and breast carcinoma. | Journal of neurosurgery 20090901 |
| Nicotinamide/nicotinic acid mononucleotide adenylyltransferase, new insights into an ancient enzyme. | Cellular and molecular life sciences : CMLS 20090901 |
| Vitamins in the monkey brain: An immunocytochemical study. | Journal of chemical neuroanatomy 20090901 |
| An EPR study of Cu2+ doped diaquabis(nicotinamide)bis(o-sulfobenzimidato-N)-cadmium(II) single crystals. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20090901 |
| Management of sorafenib, sunitinib, and temsirolimus toxicity in metastatic renal cell carcinoma. | Current opinion in supportive and palliative care 20090901 |
| Nitric oxide inhibits IFN regulatory factor 1 and nuclear factor-kappaB pathways in rhinovirus-infected epithelial cells. | The Journal of allergy and clinical immunology 20090901 |
| Targeted therapies in the treatment of advanced/metastatic NSCLC. | European journal of cancer (Oxford, England : 1990) 20090901 |
| Surgical resection of renal cell carcinoma after targeted therapy. | The Journal of urology 20090901 |
| Sorafenib induces growth inhibition and apoptosis in human synovial sarcoma cells via inhibiting the RAF/MEK/ERK signaling pathway. | Cancer biology & therapy 20090901 |
| A computational approach to compare microvessel distributions in tumors following antiangiogenic treatments. | Laboratory investigation; a journal of technical methods and pathology 20090901 |
| Bipartite recognition and conformational sampling mechanisms for hydride transfer from nicotinamide coenzyme to FMN in pentaerythritol tetranitrate reductase. | The FEBS journal 20090901 |
| In vitro hepatic differentiation of human bone marrow mesenchymal stem cells under differential exposure to liver-specific factors. | Translational research : the journal of laboratory and clinical medicine 20090901 |
| The histologic spectrum of epithelial neoplasms induced by sorafenib. | Journal of the American Academy of Dermatology 20090901 |
| Targeted therapies: Role of sorafenib in HCC patients with compromised liver function. | Nature reviews. Clinical oncology 20090901 |
| SIRT1 regulation of apoptosis of human chondrocytes. | Arthritis and rheumatism 20090901 |
| AZD6244 (ARRY-142886) enhances the therapeutic efficacy of sorafenib in mouse models of gastric cancer. | Molecular cancer therapeutics 20090901 |
| Aurora kinase inhibitor PHA-739358 suppresses growth of hepatocellular carcinoma in vitro and in a xenograft mouse model. | Neoplasia (New York, N.Y.) 20090901 |
| Uncommon isonicotinamide supramolecular synthons in copper(II) complexes directed by nitrate and perchlorate anions. | Acta crystallographica. Section C, Crystal structure communications 20090901 |
| Efficacy of anti-aging products for periorbital wrinkles as measured by 3-D imaging. | Journal of cosmetic dermatology 20090901 |
| Molecular targeting for treatment of advanced hepatocellular carcinoma. | The Korean journal of hepatology 20090901 |
| [Bemusement and strategy on the efficacy of clinical application of targeted anticancer drugs]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20090901 |
| [Clinical observation of 21 cases of metastatic renal cell carcinoma treated with sorafenib]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20090901 |
| [Clinical observation of the treatment with combination of transcatheter arterial chemoembolization and sorafenib for hepatocellular carcinoma with lung metastasis]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20090901 |
| Sorafenib inhibits non-small cell lung cancer cell growth by targeting B-RAF in KRAS wild-type cells and C-RAF in KRAS mutant cells. | Cancer research 20090815 |
| Phase II study of safety and efficacy of motesanib in patients with progressive or symptomatic, advanced or metastatic medullary thyroid cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090810 |
| Keratoacanthomas and squamous cell carcinomas in patients receiving sorafenib. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090810 |
| [Molecular targeted drugs in the developmental stage: 2) Various molecular targets and therapeutic agents under investigation]. | Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20090810 |
| Follicular hyperplasia on the face subsequent to therapy with sorafenib. A new skin side effect. | Journal of the European Academy of Dermatology and Venereology : JEADV 20090801 |
| Sorafenib and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma. | Journal of cellular and molecular medicine 20090801 |
| Hyperkeratosis of nipple skin during sorafenib treatment. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20090801 |
| Nephrotic-range proteinuria in a patient with a renal allograft treated with sorafenib for metastatic renal-cell carcinoma. | Clinical and experimental nephrology 20090801 |
| Nicotinamide enhances mitochondria quality through autophagy activation in human cells. | Aging cell 20090801 |
| Novel bUT-B2 urea transporter isoform is constitutively activated. | American journal of physiology. Regulatory, integrative and comparative physiology 20090801 |
| Regulatory role of Sirt1 on the gene expression of fatty acid-binding protein 3 in cultured porcine adipocytes. | Journal of cellular biochemistry 20090801 |
| Sorafenib and vorinostat kill colon cancer cells by CD95-dependent and -independent mechanisms. | Molecular pharmacology 20090801 |
| BCL-2 family inhibitors enhance histone deacetylase inhibitor and sorafenib lethality via autophagy and overcome blockade of the extrinsic pathway to facilitate killing. | Molecular pharmacology 20090801 |
| Nicotinamide rescues human embryonic stem cell-derived neuroectoderm from parthanatic cell death. | Stem cells (Dayton, Ohio) 20090801 |
| Discovery and structural analysis of Eph receptor tyrosine kinase inhibitors. | Bioorganic & medicinal chemistry letters 20090801 |
| Adverse effects of anticancer agents that target the VEGF pathway. | Nature reviews. Clinical oncology 20090801 |
| Array of cutaneous adverse effects associated with sorafenib. | Journal of the American Academy of Dermatology 20090801 |
| Tumor endothelial cells join the resistance. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090801 |
| Human hepatocellular carcinoma tumor-derived endothelial cells manifest increased angiogenesis capability and drug resistance compared with normal endothelial cells. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090801 |
| Diagnosis and management of leptomeningeal disease. | Clinical journal of oncology nursing 20090801 |
| Sorafenib and sunitinib. | The oncologist 20090801 |
| Development of a novel chemical class of BRAF inhibitors offers new hope for melanoma treatment. | Future oncology (London, England) 20090801 |
| [Schedule-dependent effects of sorafenib in combination with paclitaxel on human hepatocellular carcinoma cell line BEL-7402]. | Ai zheng = Aizheng = Chinese journal of cancer 20090801 |
| Sorafenib has soluble epoxide hydrolase inhibitory activity, which contributes to its effect profile in vivo. | Molecular cancer therapeutics 20090801 |
| Safety and efficacy of sorafenib therapy in patients with metastatic kidney cancer with impaired renal function. | Clinical genitourinary cancer 20090801 |
| Response of retinoic acid-resistant KG1 cells to combination of retinoic acid with diverse histone deacetylase inhibitors. | Annals of the New York Academy of Sciences 20090801 |
| Phase II multicenter, uncontrolled trial of sorafenib in patients with metastatic breast cancer. | Anti-cancer drugs 20090801 |
| Combined experimental and quantum chemical investigation of chiroptical properties of nicotinamide derivatives with and without intramolecular cation-pi interactions. | The journal of physical chemistry. A 20090730 |
| Experimental and computational studies on non-covalent imprinted microspheres as recognition system for nicotinamide molecules. | Molecules (Basel, Switzerland) 20090717 |
| Therapeutic Drug Monitoring of the new targeted anticancer agents imatinib, nilotinib, dasatinib, sunitinib, sorafenib and lapatinib by LC tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090715 |
| Targeting renal cell carcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090710 |
| Sorafenib for treatment of renal cell carcinoma: Final efficacy and safety results of the phase III treatment approaches in renal cancer global evaluation trial. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090710 |
| New catalytic liquid-phase ammoxidation approach to the preparation of niacin (vitamin B3). | Langmuir : the ACS journal of surfaces and colloids 20090707 |
| Eosin Y-sensitized artificial photosynthesis by highly efficient visible-light-driven regeneration of nicotinamide cofactor. | Chembiochem : a European journal of chemical biology 20090706 |
| A case of familial tumoral calcinosis/hyperostosis-hyperphosphatemia syndrome due to a compound heterozygous mutation in GALNT3 demonstrating new phenotypic features. | Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20090701 |
| Inhibition of choroidal neovascularisation in mice by systemic administration of the multikinase inhibitor, sorafenib. | The British journal of ophthalmology 20090701 |
| Role of RAF/MEK/ERK pathway, p-STAT-3 and Mcl-1 in sorafenib activity in human pancreatic cancer cell lines. | Journal of cellular physiology 20090701 |
| Evolution of soil biological properties after addition of glyphosate, diflufenican and glyphosate+diflufenican herbicides. | Chemosphere 20090701 |
| Endofacial competitive inhibition of the glucose transporter 1 activity by gossypol. | American journal of physiology. Cell physiology 20090701 |
| Mice lacking the ADP ribosyl cyclase CD38 exhibit attenuated renal vasoconstriction to angiotensin II, endothelin-1, and norepinephrine. | American journal of physiology. Renal physiology 20090701 |
| Sorafenib tosylate in advanced kidney cancer: past, present and future. | Anti-cancer drugs 20090701 |
| Sequential sorafenib and sunitinib for renal cell carcinoma. | The Journal of urology 20090701 |
| Technetium-binding in labelled HYNIC-peptide conjugates: role of coordinating amino acids. | Journal of inorganic biochemistry 20090701 |
| Phase II study of sorafenib in patients with metastatic or recurrent sarcomas. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090701 |
| VEGF inhibition and metastasis: possible implications for antiangiogenic therapy. | Cancer biology & therapy 20090701 |
| Evaluation of sorafenib treatment in metastatic renal cell carcinoma with 2-fluoro-2-deoxyglucose positron emission tomography and computed tomography. | Nuclear medicine communications 20090701 |
| Cytoreductive nephrectomy for metastatic RCC in the era of targeted therapy. | Nature reviews. Urology 20090701 |
| Multiple Histology Phase II Trials. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090701 |
| Multiple colon ulcerations, perforation and death during treatment of malignant melanoma with sorafenib. | Deutsche medizinische Wochenschrift (1946) 20090701 |
| Portal vein tumor thrombosis revascularization during sorafenib treatment for hepatocellular carcinoma. | The American journal of gastroenterology 20090701 |
| Current management of hepatocellular carcinoma. | The Medical clinics of North America 20090701 |
| Histone acetylation, VERNALIZATION INSENSITIVE 3, FLOWERING LOCUS C, and the vernalization response. | Molecular plant 20090701 |
| Compassionate use of sorafenib in FLT3-ITD-positive acute myeloid leukemia: sustained regression before and after allogeneic stem cell transplantation. | Blood 20090625 |
| Induced fit and equilibrium dynamics for high catalytic efficiency in ferredoxin-NADP(H) reductases. | Biochemistry 20090623 |
| Assimilation of endogenous nicotinamide riboside is essential for calorie restriction-mediated life span extension in Saccharomyces cerevisiae. | The Journal of biological chemistry 20090619 |
| NF-kappaB inhibition in human hepatocellular carcinoma and its potential as adjunct to sorafenib based therapy. | Cancer letters 20090618 |
| The crystal structure of BRAF in complex with an organoruthenium inhibitor reveals a mechanism for inhibition of an active form of BRAF kinase. | Biochemistry 20090616 |
| How well do angiogenesis inhibitors work? Biomarkers of response prove elusive. | Journal of the National Cancer Institute 20090616 |
| Resveratrol prevents doxorubicin cardiotoxicity through mitochondrial stabilization and the Sirt1 pathway. | Free radical biology & medicine 20090615 |
| Discovery of N-{N-[(3-cyanophenyl)sulfonyl]-4(R)-cyclobutylamino-(L)-prolyl}-4-[(3',5'-dichloroisonicotinoyl) amino]-(L)-phenylalanine (MK-0668), an extremely potent and orally active antagonist of very late antigen-4. | Journal of medicinal chemistry 20090611 |
| Apoptosis of CD4(+)CD25(high) T cells in response to Sirolimus requires activation of T cell receptor and is modulated by IL-2. | Cancer immunology, immunotherapy : CII 20090601 |
| Editorial comment on: Can tyrosine kinase inhibitors be discontinued in patients with metastatic renal cell carcinoma and a complete response to treatment? A multicentre, retrospective analysis. | European urology 20090601 |
| Can tyrosine kinase inhibitors be discontinued in patients with metastatic renal cell carcinoma and a complete response to treatment? A multicentre, retrospective analysis. | European urology 20090601 |
| Adipose tissue as a source of nicotinamide N-methyltransferase and homocysteine. | Atherosclerosis 20090601 |
| Final analysis of a phase II trial using sorafenib for metastatic castration-resistant prostate cancer. | BJU international 20090601 |
| A novel FIP1L1-PDGFRA mutant destabilizing the inactive conformation of the kinase domain in chronic eosinophilic leukemia/hypereosinophilic syndrome. | Allergy 20090601 |
| Epidemiology, screening, diagnosis and treatment of hepatocellular carcinoma. | Minerva gastroenterologica e dietologica 20090601 |
| [Toxicity of radiation therapy and antiangiogenics combination: a case report]. | Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique 20090601 |
| Preclinical development of the nicotinamide phosphoribosyl transferase inhibitor prodrug GMX1777. | Anti-cancer drugs 20090601 |
| Antiviral effect of nicotinamide on enterovirus-infected human islets in vitro: effect on virus replication and chemokine secretion. | Journal of medical virology 20090601 |
| A systems biology perspective on cholangiocellular carcinoma development: focus on MAPK-signaling and the extracellular environment. | Journal of hepatology 20090601 |
| Long lasting response to the multikinase inhibitor bay 43-9006 (Sorafenib) in a heavily pretreated metastatic thymic carcinoma. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20090601 |
| BRAF signaling and targeted therapies in melanoma. | Hematology/oncology clinics of North America 20090601 |
| Does arterial spin-labeling MR imaging-measured tumor perfusion correlate with renal cell cancer response to antiangiogenic therapy in a mouse model? | Radiology 20090601 |
| Sorafenib therapy in advanced hepatocellular carcinoma: the SHARP trial. | Expert review of anticancer therapy 20090601 |
| The role of antiangiogenesis therapy: bevacizumab and beyond. | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20090601 |
| Localized dyskeratotic plaque with milia associated with sorafenib. | Journal of drugs in dermatology : JDD 20090601 |
| [Sorafenib(Nexavar)]. | Gan to kagaku ryoho. Cancer & chemotherapy 20090601 |
| [Current advances in molecular targeted therapy of primary hepatocellular carcinoma]. | Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20090601 |
| Anticalculus efficacy of a new dentifrice. | Quintessence international (Berlin, Germany : 1985) 20090601 |
| [Interferon alpha and half-dose sorafenib is an effective treatment modality for interferon alpha-resistant metastatic renal cell carcinoma: a case report]. | Hinyokika kiyo. Acta urologica Japonica 20090601 |
| Consideration of diurnal variations in human blood NAD and NADP concentrations. | Journal of nutritional science and vitaminology 20090601 |
| VEGF inhibitors and prostate cancer therapy. | Current molecular pharmacology 20090601 |
| [Expert consensus on standardization of the management of primary liver cancer]. | Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20090601 |
| Synergistic effect of Sorafenib and Sunitinib with Enzastaurin, a selective protein kinase C inhibitor in renal cell carcinoma cell lines. | Cancer letters 20090518 |
| Modulatory effects of resveratrol on attenuating the key enzymes activities of carbohydrate metabolism in streptozotocin-nicotinamide-induced diabetic rats. | Chemico-biological interactions 20090515 |
| Vascular endothelial growth factor-targeted therapy in metastatic renal cell carcinoma. | Cancer 20090515 |
| Detection and pharmacological modulation of nicotinamide mononucleotide (NMN) in vitro and in vivo. | Biochemical pharmacology 20090515 |
| Perforating folliculitis, angioedema, hand-foot syndrome--multiple cutaneous side effects in a patient treated with sorafenib. | Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20090501 |
| FIP1L1-PDGFRalpha D842V, a novel panresistant mutant, emerging after treatment of FIP1L1-PDGFRalpha T674I eosinophilic leukemia with single agent sorafenib. | Leukemia 20090501 |
| Characterization of histamine H3 receptors in Alzheimer's Disease brain and amyloid over-expressing TASTPM mice. | British journal of pharmacology 20090501 |
| Validation of an HPLC-UV method for sorafenib determination in human plasma and application to cancer patients in routine clinical practice. | Journal of pharmaceutical and biomedical analysis 20090501 |
| Resveratrol inhibits proliferation and promotes apoptosis of osteosarcoma cells. | European journal of pharmacology 20090501 |
| Circadian control of the NAD+ salvage pathway by CLOCK-SIRT1. | Science (New York, N.Y.) 20090501 |
| Recent advances in molecular targeted therapy for metastatic renal cell carcinoma. | International journal of urology : official journal of the Japanese Urological Association 20090501 |
| [Targeted therapies and their indications in solid neoplasias]. | La Revue de medecine interne 20090501 |
| Targeting angiogenesis in bladder cancer. | Current oncology reports 20090501 |
| Antitumor efficacy of recombinant human interleukin-2 combined with sorafenib against mouse renal cell carcinoma. | Japanese journal of clinical oncology 20090501 |
| Targeted therapies in metastatic renal cancer in 2009. | BJU international 20090501 |
| Sorafenib targets dysregulated Rho kinase expression and portal hypertension in rats with secondary biliary cirrhosis. | British journal of pharmacology 20090501 |
| Sorafenib induces apoptosis specifically in cells expressing BCR/ABL by inhibiting its kinase activity to activate the intrinsic mitochondrial pathway. | Cancer research 20090501 |
| Cardiac dysfunction induced by novel targeted anticancer therapy: an emerging issue. | Current cardiology reports 20090501 |
| Pathogenesis of hepatocellular carcinoma and molecular therapies. | Current opinion in gastroenterology 20090501 |
| Arterial hypertension and clinical benefit of sunitinib, sorafenib and bevacizumab in first and second-line treatment of metastatic renal cell cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20090501 |
| Differential effects of acute and repeat dosing with the H3 antagonist GSK189254 on the sleep-wake cycle and narcoleptic episodes in Ox-/- mice. | British journal of pharmacology 20090501 |
| Prognostic markers and new, innovative treatments in renal cell carcinoma. | Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20090501 |
| Is hypothyroidism a clinically relevant toxicity of tyrosine kinase inhibitors? | Thyroid : official journal of the American Thyroid Association 20090501 |
| [Sorafenib reverses multidrug resistance of hepatoma cells in vitro]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20090501 |
| Angiogenesis regulated by VEGF and its receptors and its clinical application. | [Rinsho ketsueki] The Japanese journal of clinical hematology 20090501 |
| Diffuse-type gastric carcinoma: progression, angiogenesis, and transforming growth factor beta signaling. | Journal of the National Cancer Institute 20090415 |
| Phase I and pharmacokinetic study of sorafenib in patients with hepatic or renal dysfunction: CALGB 60301. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090410 |
| Influence of bevacizumab, sunitinib and sorafenib as single agents or in combination on the inhibitory effects of VEGF on human dendritic cell differentiation from monocytes. | British journal of cancer 20090407 |
| [The treatment of hepatocellular carcinoma. New developments]. | Nederlands tijdschrift voor geneeskunde 20090404 |
| SIRT1 regulates tyrosine hydroxylase expression and differentiation of neuroblastoma cells via FOXO3a. | FEBS letters 20090402 |
| Practical efficacy of sorafenib monotherapy for advanced hepatocellular carcinoma patients in a Hepatitis B virus-endemic area. | Journal of cancer research and clinical oncology 20090401 |
| Carbogen and nicotinamide in locally advanced bladder cancer: early results of a phase-III randomized trial. | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20090401 |
| Successful sorafenib treatment for metastatic renal cell carcinoma in a case with chronic renal failure. | European urology 20090401 |
| Accelerated radiotherapy, carbogen, and nicotinamide (ARCON) in the treatment of advanced bladder cancer: mature results of a Phase II nonrandomized study. | International journal of radiation oncology, biology, physics 20090401 |
| Beneficial effects of sorafenib on splanchnic, intrahepatic, and portocollateral circulations in portal hypertensive and cirrhotic rats. | Hepatology (Baltimore, Md.) 20090401 |
| Production of L-tryptophan-derived catabolites in hepatocytes from streptozotocin-induced diabetic rats. | European journal of nutrition 20090401 |
| Nicotinamide and its metabolite N-methylnicotinamide increase skin vascular permeability in rats. | Clinical and experimental dermatology 20090401 |
| Phase II trial of sorafenib in metastatic thyroid cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090401 |
| Efficient exploration of large combinatorial chemistry spaces by monomer-based similarity searching. | Journal of chemical information and modeling 20090401 |
| FMS-like tyrosine kinase 3-internal tandem duplication tyrosine kinase inhibitors display a nonoverlapping profile of resistance mutations in vitro. | Cancer research 20090401 |
| [Hepatocellular carcinoma management in the era of sorafenib]. | Gastroenterologie clinique et biologique 20090401 |
| Response to sorafenib after sunitinib-induced acute heart failure in a patient with metastatic renal cell carcinoma: case report and review of the literature. | Pharmacotherapy 20090401 |
| Antiangiogenic therapy: not just for cancer anymore? | Hepatology (Baltimore, Md.) 20090401 |
| Hypothyroidism related to tyrosine kinase inhibitors: an emerging toxic effect of targeted therapy. | Nature reviews. Clinical oncology 20090401 |
| PDGFRalpha: a new therapeutic target in the treatment of hepatocellular carcinoma? | Expert opinion on therapeutic targets 20090401 |
| [Reversion of drug-resistant hepatocellular carcinoma cell line BEL-7402/FU by sorafenib]. | Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20090401 |
| The successful use of sorafenib to treat pediatric papillary thyroid carcinoma. | Thyroid : official journal of the American Thyroid Association 20090401 |
| Role of B-Raf(V600E) in differentiated thyroid cancer and preclinical validation of compounds against B-Raf(V600E). | Biochimica et biophysica acta 20090401 |
| Cardiovascular toxicities: clues to optimal administration of vascular endothelial growth factor signaling pathway inhibitors. | Targeted oncology 20090401 |
| Selection of patients with hepatocellular carcinoma for sorafenib. | Journal of the National Comprehensive Cancer Network : JNCCN 20090401 |
| Renal toxicity of targeted therapies. | Targeted oncology 20090401 |
| Reversible interactions with para-hydrogen enhance NMR sensitivity by polarization transfer. | Science (New York, N.Y.) 20090327 |
| FDH: an aldehyde dehydrogenase fusion enzyme in folate metabolism. | Chemico-biological interactions 20090316 |
| Stabilization and conformational isomerization of the cofactor during the catalysis in hydrolytic ALDHs. | Chemico-biological interactions 20090316 |
| Randomized phase II trial of first-line treatment with sorafenib versus interferon Alfa-2a in patients with metastatic renal cell carcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090310 |
| Antioxidant metabolism induced by quinic acid. Increased urinary excretion of tryptophan and nicotinamide. | Phytotherapy research : PTR 20090301 |
| Combination of sorafenib and doxorubicin in patients with advanced hepatocellular carcinoma: results from a phase I extension trial. | European journal of cancer (Oxford, England : 1990) 20090301 |
| Effects of the combination of dipeptidyl peptidase-IV inhibitor ASP8497 and antidiabetic drugs in streptozotocin-nicotinamide-induced mildly diabetic mice. | European journal of pharmacology 20090301 |
| Multimodal approaches to the treatment of hepatocellular carcinoma. | Nature clinical practice. Gastroenterology & hepatology 20090301 |
| Unexpected autocrine role of vascular endothelial growth factor in squamous cell carcinoma. | The Journal of investigative dermatology 20090301 |
| Antidiabetic effects of dipeptidyl peptidase-IV inhibitors and sulfonylureas in streptozotocin-nicotinamide-induced mildly diabetic mice. | Metabolism: clinical and experimental 20090301 |
| Nicotinamide as a potential novel addition to the anti-uremic pruritus weaponry. | Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20090301 |
| Dietary B vitamin and methionine intakes and plasma folate are not associated with colorectal cancer risk in Chinese women. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20090301 |
| Biochemical characterization, localization, and tissue distribution of the longer form of mouse SIRT3. | Protein science : a publication of the Protein Society 20090301 |
| Recommendations from the Spanish Oncology Genitourinary Group for the treatment of metastatic renal cancer. | Cancer chemotherapy and pharmacology 20090301 |
| Zero-, one- and two-dimensional hydrogen-bonded structures in the 1:1 proton-transfer compounds of 4,5-dichlorophthalic acid with the monocyclic heteroaromatic Lewis bases 2-aminopyrimidine, nicotinamide and isonicotinamide. | Acta crystallographica. Section C, Crystal structure communications 20090301 |
| Recent advances in the systemic treatment of metastatic papillary renal cancer. | Expert review of anticancer therapy 20090301 |
| Molecular determinants of melanoma malignancy: selecting targets for improved efficacy of chemotherapy. | Molecular cancer therapeutics 20090301 |
| Tie2 in tumor endothelial signaling and survival: implications for antiangiogenic therapy. | Molecular cancer research : MCR 20090301 |
| Effect of nicotinamide on experimental induced diabetes. | Iranian journal of allergy, asthma, and immunology 20090301 |
| Systemic treatment in hepatocellular carcinoma; 'A small step for man...'. | The Netherlands journal of medicine 20090301 |
| beta-1,2,3-Triazolyl-nucleosides as nicotinamide riboside mimics. | Nucleosides, nucleotides & nucleic acids 20090301 |
| Emerging data with antiangiogenic therapies in early and advanced non-small-cell lung cancer. | Clinical lung cancer 20090301 |
| [Palliative management of hepatocarcinoma with sorafenib (Nexavar). Results of the SHARP study (sorafenib hepatocarcinoma assessment randomized protocol trial)]. | Revue medicale de Liege 20090301 |
| [Diagnosis and treatment of hepatocellular carcinoma]. | Medicina clinica 20090227 |
| Major achievements in hepatocellular carcinoma. | Lancet (London, England) 20090221 |
| Testing molecular therapies in hepatocellular carcinoma: the need for randomized phase II trials. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090220 |
| 3,4-Disubstituted isothiazoles: novel potent inhibitors of VEGF receptors 1 and 2. | Bioorganic & medicinal chemistry letters 20090215 |
| Hand-foot skin reaction increases with cumulative sorafenib dose and with combination anti-vascular endothelial growth factor therapy. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090215 |
| Antidiabetic effect through islet cell protection in streptozotocin diabetes: a preliminary assessment of two thiazolidin-4-ones in Swiss albino mice. | Chemico-biological interactions 20090212 |
| Emerging roles of NAD+ and its metabolites in cell signaling. | Science signaling 20090210 |
| Role of sirtuin histone deacetylase SIRT1 in prostate cancer. A target for prostate cancer management via its inhibition? | The Journal of biological chemistry 20090206 |
| Sorafenib and surgical complications: a case report of adverse reaction to sorafenib during treatment for renal cell carcinoma. | European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20090201 |
| Sorafenib (Nexavar) induces molecular remission and regression of extramedullary disease in a patient with FLT3-ITD+ acute myeloid leukemia. | Leukemia research 20090201 |
| Chronic inhibition of dipeptidyl peptidase-IV with ASP8497 improved the HbA(1c) level, glucose intolerance, and lipid parameter level in streptozotocin-nicotinamide-induced diabetic mice. | Naunyn-Schmiedeberg's archives of pharmacology 20090201 |
| Dermatologic symptoms associated with the multikinase inhibitor sorafenib. | Journal of the American Academy of Dermatology 20090201 |
| Nicotinamide cooperates with retinoic acid and 1,25-dihydroxyvitamin D(3) to regulate cell differentiation and cell cycle arrest of human myeloblastic leukemia cells. | Oncology 20090201 |
| Treating hepatocellular carcinoma without liver transplantation. | Current gastroenterology reports 20090201 |
| Expression of sorafenib targets in melanoma patients treated with carboplatin, paclitaxel and sorafenib. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090201 |
| MAPK-independent impairment of T-cell responses by the multikinase inhibitor sorafenib. | Molecular cancer therapeutics 20090201 |
| Comparison of the nicotinamide catabolism among rat strains. | Bioscience, biotechnology, and biochemistry 20090201 |
| Blood flow and Vd (water): both biomarkers required for interpreting the effects of vascular targeting agents on tumor and normal tissue. | Molecular cancer therapeutics 20090201 |
| Sorafenib induces therapeutic response in a patient with metastatic collecting duct carcinoma of kidney. | Onkologie 20090201 |
| Remission of paraneoplastic dermatomyositis associated with hepatocellular carcinoma under prednisolone and azathiopin, and concommittant sorafenib. | Onkologie 20090201 |
| Sorafenib is active on lung metastases from synovial sarcoma. | Annals of oncology : official journal of the European Society for Medical Oncology 20090201 |
| [Hand-foot syndrome and sorafenib]. | Bulletin du cancer 20090201 |
| Concurrent regulation of AMP-activated protein kinase and SIRT1 in mammalian cells. | Biochemical and biophysical research communications 20090123 |
| Phase 2 open-label study of single-agent sorafenib in treating advanced hepatocellular carcinoma in a hepatitis B-endemic Asian population: presence of lung metastasis predicts poor response. | Cancer 20090115 |
| Liquid chromatography-tandem mass spectrometric assay for sorafenib and sorafenib-glucuronide in mouse plasma and liver homogenate and identification of the glucuronide metabolite. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090115 |
| Enantioselective, ketoreductase-based entry into pharmaceutical building blocks: ethanol as tunable nicotinamide reductant. | Organic letters 20090115 |
| Molecular therapy for the treatment of hepatocellular carcinoma. | British journal of cancer 20090113 |
| Metastatic sarcomatoid renal cell carcinoma treated with vascular endothelial growth factor-targeted therapy. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090110 |
| CRAF inhibition induces apoptosis in melanoma cells with non-V600E BRAF mutations. | Oncogene 20090108 |
| On the thermodynamics of cocrystal formation. | International journal of pharmaceutics 20090105 |
| Nicotinamide riboside and nicotinic acid riboside salvage in fungi and mammals. Quantitative basis for Urh1 and purine nucleoside phosphorylase function in NAD+ metabolism. | The Journal of biological chemistry 20090102 |
| SIRT1 promotes differentiation of normal human keratinocytes. | The Journal of investigative dermatology 20090101 |
| Pre-treatment global quality of health predicts progression free survival in metastatic kidney cancer patients treated with sorafenib or sunitinib. | Journal of cancer research and clinical oncology 20090101 |
| Long-lasting successful cerebral response with sorafenib in advanced renal cell carcinoma. | Journal of neuro-oncology 20090101 |
| The relationship between pyridine nucleotides and seed dormancy. | The New phytologist 20090101 |
| Theoretical study of the vibrational spectra of the hydrogen-bonded systems between pyridine-3-carboxamide (nicotinamide) and DMSO. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20090101 |
| Response to sorafenib in cisplatin-resistant thymic carcinoma: a case report. | Medical oncology (Northwood, London, England) 20090101 |
| An increased regional blood flow precedes mesenteric inflammation in rats treated by a phosphodiesterase 4 inhibitor. | Toxicological sciences : an official journal of the Society of Toxicology 20090101 |
| Oral nicotinamide protects against ultraviolet radiation-induced immunosuppression in humans. | Carcinogenesis 20090101 |
| Comparison of the effects of the kinase inhibitors imatinib, sorafenib, and transforming growth factor-beta receptor inhibitor on extravasation of nanoparticles from neovasculature. | Cancer science 20090101 |
| Phase II trial of sorafenib in patients with metastatic breast cancer previously exposed to anthracyclines or taxanes: North Central Cancer Treatment Group and Mayo Clinic Trial N0336. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090101 |
| Quo vadis with targeted drugs in the 21st century? | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090101 |
| Sequential therapy with sorafenib and sunitinib in renal cell carcinoma. | Cancer 20090101 |
| Combination of sorafenib and intensity modulated radiotherapy for unresectable hepatocellular carcinoma. | Clinical drug investigation 20090101 |
| Multiple keratoacanthomas arising in the setting of sorafenib therapy: novel chemoprophylaxis with bexarotene. | Cancer control : journal of the Moffitt Cancer Center 20090101 |
| Transformation and action of extracellular NAD+ in perfused rat and mouse livers. | Acta pharmacologica Sinica 20090101 |
| Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial. | The Lancet. Oncology 20090101 |
| Acute hepatitis in a patient with cirrhosis and hepatocellular carcinoma treated with sorafenib. | The American journal of gastroenterology 20090101 |
| Sorafenib for liver cancer: the horizon broadens. | The Lancet. Oncology 20090101 |
| Broad antitumor activity in breast cancer xenografts by motesanib, a highly selective, oral inhibitor of vascular endothelial growth factor, platelet-derived growth factor, and Kit receptors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090101 |
| Management of advanced hepatocellular carcinoma in the era of targeted therapy. | Liver international : official journal of the International Association for the Study of the Liver 20090101 |
| Sorafenib induces growth suppression in mouse models of gastrointestinal stromal tumor. | Molecular cancer therapeutics 20090101 |
| Sorafenib for the treatment of unresectable hepatocellular carcinoma. | The oncologist 20090101 |
| Commentary: Sorafenib -- the end of a long journey in search of systemic therapy for hepatocellular carcinoma, or the beginning? | The oncologist 20090101 |
| Sorafenib in unresectable hepatocellular carcinoma from mild to advanced stage liver cirrhosis. | The oncologist 20090101 |
| Commentary: Sorafenib use in patients with advanced hepatocellular carcinoma and underlying Child-Pugh B cirrhosis: evidence and controversy. | The oncologist 20090101 |
| Nicotinamide phosphoribosyltransferase (Nampt): a link between NAD biology, metabolism, and diseases. | Current pharmaceutical design 20090101 |
| [Sorafenib for the treatment of HCC--the beginning of a new era in the treatment of HCC]. | Zeitschrift fur Gastroenterologie 20090101 |
| Metastatic renal cell cancer treatments: an indirect comparison meta-analysis. | BMC cancer 20090101 |
| [Interdisciplinary recommendations for the treatment of metastatic renal cell carcinoma]. | Aktuelle Urologie 20090101 |
| [Medical treatment of metastatic renal cell carcinoma after the approval and market entry of multitargeted tyrosine kinase inhibitors in Germany]. | Aktuelle Urologie 20090101 |
| Pharmacokinetics of sorafenib in patients with renal impairment undergoing hemodialysis. | International journal of clinical pharmacology and therapeutics 20090101 |
| New drugs for the treatment of hepatocellular carcinoma. | Liver international : official journal of the International Association for the Study of the Liver 20090101 |
| Tyrosine kinase inhibitors in advanced renal cell carcinoma: the evolving treatment paradigm. | Clinical genitourinary cancer 20090101 |
| Cutaneous squamous cell carcinoma and inflammation of actinic keratoses associated with sorafenib. | Clinical genitourinary cancer 20090101 |
| Sorafenib: a review of its use in advanced hepatocellular carcinoma. | Drugs 20090101 |
| Retrospective analysis of the safety and efficacy of interleukin-2 after prior VEGF-targeted therapy in patients with advanced renal cell carcinoma. | Journal of immunotherapy (Hagerstown, Md. : 1997) 20090101 |
| Safety and efficacy of sorafenib in patients with advanced hepatocellular carcinoma in consideration of concomitant stage of liver cirrhosis. | Journal of clinical gastroenterology 20090101 |
| [Established therapies for skin diseases. Vitamins in dermatology]. | Pharmazie in unserer Zeit 20090101 |
| Nicotinamide prevents NAD+ depletion and protects neurons against excitotoxicity and cerebral ischemia: NAD+ consumption by SIRT1 may endanger energetically compromised neurons. | Neuromolecular medicine 20090101 |
| Activation of nicotinamide N-methyltrasferase and increased formation of 1-methylnicotinamide (MNA) in atherosclerosis. | Pharmacological reports : PR 20090101 |
| Anti-diabetic effects of 1-methylnicotinamide (MNA) in streptozocin-induced diabetes in rats. | Pharmacological reports : PR 20090101 |
| Sunitinib treatment for patients with advanced clear-cell renal-cell carcinoma after progression on sorafenib. | Oncology 20090101 |
| Bullous pemphigoid in a renal transplant recipient: a case report and review of the literature. | American journal of clinical dermatology 20090101 |
| Rapamycin weekly maintenance dosing and the potential efficacy of combination sorafenib plus rapamycin but not atorvastatin or doxycycline in tuberous sclerosis preclinical models. | BMC pharmacology 20090101 |
| Selecting promising treatments in randomized Phase II cancer trials with an active control. | Journal of biopharmaceutical statistics 20090101 |
| [Prospect of hepatocellular carcinoma in 2008]. | Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20090101 |
| Evidence and values: requirements for public reimbursement of drugs for rare diseases--a case study in oncology. | The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique 20090101 |
| The reverse side of the victory: flare up of symptoms after discontinuation of sunitinib or sorafenib in renal cell cancer patients. A report of three cases. | Acta oncologica (Stockholm, Sweden) 20090101 |
| A case of acute haemolysis with 2 different multi target thyrosine kinase inhibitors in a patient with renal cancer. | Bulletin de la Societe des sciences medicales du Grand-Duche de Luxembourg 20090101 |
| Sorafenib-induced erythema multiforme in metastatic renal cell carcinoma. | Cutaneous and ocular toxicology 20090101 |
| Investigation of niacin on parameters of metabolism in a physiologic dose: randomized, double-blind clinical trial with three different dosages. | International journal of food sciences and nutrition 20090101 |
| [Clinical observation of sorafenib monotherapy in Chinese patients with advanced hepatocellular carcinoma]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20090101 |
| Early MRI response monitoring of patients with advanced hepatocellular carcinoma under treatment with the multikinase inhibitor sorafenib. | BMC cancer 20090101 |
| Target therapy for hepatocellular carcinoma: is sorafenib for everybody? | Journal of clinical gastroenterology 20090101 |
| Efficacy of sorafenib on metastatic renal cell carcinoma in Asian patients: results from a multicenter study. | BMC cancer 20090101 |
| Sequential hepatogenic transdifferentiation of adipose tissue-derived stem cells: relevance of different extracellular signaling molecules, transcription factors involved, and expression of new key marker genes. | Cell transplantation 20090101 |
| A case of complete clinical response with sorafenib in a patient with thyroid gland metastases from renal cell carcinoma 17 years from diagnosis. | Tumori 20090101 |
| Common cosmeceuticals. | Clinics in dermatology 20090101 |
| Cosmeceuticals vitamins. | Clinics in dermatology 20090101 |
| Phosphorylated ERK is a potential predictor of sensitivity to sorafenib when treating hepatocellular carcinoma: evidence from an in vitro study. | BMC medicine 20090101 |
| Predicting the response to sorafenib in hepatocellular carcinoma: where is the evidence for phosphorylated extracellular signaling-regulated kinase (pERK)? | BMC medicine 20090101 |
| Successful topical treatment of sorafenib-induced hand-foot skin reaction in a child with hepatocellular carcinoma. | Pediatric dermatology 20090101 |
| [Dermatologic toxicity to sorafenib]. | Actas dermo-sifiliograficas 20090101 |
| [Sorafenib: effectiveness versus safety. Prevention of hand-foot syndrome]. | Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20090101 |
| The effect of oral niacinamide on plasma phosphorus levels in peritoneal dialysis patients. | Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20090101 |
| [Cytoflavine effect on exudative-destructive manifestations of lung tuberculosis in children and teenagers]. | Eksperimental'naia i klinicheskaia farmakologiia 20090101 |
| New therapeutic approaches in the management of metastatic renal cell carcinoma. | Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20090101 |
| HIPK2 modulates p53 activity towards pro-apoptotic transcription. | Molecular cancer 20090101 |
| Use of sorafenib in two metastatic renal cell cancer patients with end-stage renal impairment undergoing replacement hemodialysis. | Tumori 20090101 |
| Proliferation and survival molecules implicated in the inhibition of BRAF pathway in thyroid cancer cells harbouring different genetic mutations. | BMC cancer 20090101 |
| Antihyperglycemic effects of ASP8497 in streptozotocin-nicotinamide induced diabetic rats: comparison with other dipeptidyl peptidase-IV inhibitors. | Pharmacological reports : PR 20090101 |
| Successful treatment of a brain-metastasized renal cell carcinoma. | German medical science : GMS e-journal 20090101 |
| Hand-foot syndrome (hand-foot skin reaction, palmar-plantar erythrodysesthesia): focus on sorafenib and sunitinib. | Oncology 20090101 |
| Salvage therapy with sorafenib plus vinblastine and fluorouracil for metastatic renal cell carcinoma. | Acta oncologica (Stockholm, Sweden) 20090101 |
| Phenotypic plasticity in fungi: a review with observations on Aureobasidium pullulans. | Mycologia 20090101 |
| Generalized convulsions due to sorafenib-induced hypocalcemia. | Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology 20090101 |
| New pharmacological developments in the treatment of hepatocellular cancer. | Drugs 20090101 |
| Sorafenib blocks tumour growth, angiogenesis and metastatic potential in preclinical models of osteosarcoma through a mechanism potentially involving the inhibition of ERK1/2, MCL-1 and ezrin pathways. | Molecular cancer 20090101 |
| [Pathogenetic therapy of tuberculosis of respiratory organs during sanatorium-and-spa treatment]. | Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury 20090101 |
| Evaluation of the susceptibility of the pea aphid, Acyrthosiphon pisum, to a selection of novel biorational insecticides using an artificial diet. | Journal of insect science (Online) 20090101 |
| [Effect of cytoflavine on bioenergetic processes in the liver after severe limb compression trauma]. | Eksperimental'naia i klinicheskaia farmakologiia 20090101 |
| Competing forces of nature: improving the odds with full disclosure. | Oxidative medicine and cellular longevity 20090101 |
| Attenuation of bromobenzene-induced hepatotoxicity by poly(ADP-ribose) polymerase inhibitors. | Research communications in molecular pathology and pharmacology 20090101 |
| Sorafenib in hepatocellular carcinoma: separating the hype from the hope. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081220 |
| Hydrotropic polymer micelles containing acrylic acid moieties for oral delivery of paclitaxel. | Journal of controlled release : official journal of the Controlled Release Society 20081218 |
| Structure analysis of aromatic medicines containing nitrogen using near-infrared spectroscopy and generalized two-dimensional correlation spectroscopy. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20081215 |
| Targeting metastatic melanoma. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20081215 |
| Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081210 |
| Quantitative investigation of trigonelline, nicotinic acid, and nicotinamide in foods, urine, and plasma by means of LC-MS/MS and stable isotope dilution analysis. | Journal of agricultural and food chemistry 20081210 |
| Highly dissociative and concerted mechanism for the nicotinamide cleavage reaction in Sir2Tm enzyme suggested by ab initio QM/MM molecular dynamics simulations. | Journal of the American Chemical Society 20081210 |
| Sorafenib in advanced hepatocellular carcinoma. | The New England journal of medicine 20081204 |
| Sorafenib in advanced hepatocellular carcinoma. | The New England journal of medicine 20081204 |
| Sorafenib in advanced hepatocellular carcinoma. | The New England journal of medicine 20081204 |
| Spectroscopic studies on the interaction between nicotinamide and bovine serum albumin. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20081201 |
| Sorafenib triggers antiproliferative and pro-apoptotic signals in human esophageal adenocarcinoma cells. | Digestive diseases and sciences 20081201 |
| Sequential use of the tyrosine kinase inhibitors sorafenib and sunitinib in metastatic renal cell carcinoma: a retrospective outcome analysis. | European urology 20081201 |
| Hypoglycaemic effects of antidiabetic drugs in streptozotocin-nicotinamide-induced mildly diabetic and streptozotocin-induced severely diabetic rats. | Basic & clinical pharmacology & toxicology 20081201 |
| Exploring the role of novel agents in the treatment of renal cell carcinoma. | Cancer treatment reviews 20081201 |
| Review article: pharmacological therapy for hepatocellular carcinoma with sorafenib and other oral agents. | Alimentary pharmacology & therapeutics 20081201 |
| Separation of flavins and nicotinamide cofactors in Chinese hamster ovary cells by capillary electrophoresis. | Biomedical chromatography : BMC 20081201 |
| Effects of antidiabetic drugs on glucose tolerance in streptozotocin-nicotinamide-induced mildly diabetic and streptozotocin-induced severely diabetic mice. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20081201 |
| Vascular complications of selected cancer therapies. | Nature clinical practice. Cardiovascular medicine 20081201 |
| Complete response of stage IV anal mucosal melanoma expressing KIT Val560Asp to the multikinase inhibitor sorafenib. | Nature clinical practice. Oncology 20081201 |
| SAR profiles of spirocyclic nicotinamide derived selective HDAC1/HDAC2 inhibitors (SHI-1:2). | Bioorganic & medicinal chemistry letters 20081201 |
| Optimization of crucial reaction conditions for the production of nicotinamide by nitrile hydratase using response surface methodology. | Applied biochemistry and biotechnology 20081201 |
| Gastroduodenal mucosal defense. | Current gastroenterology reports 20081201 |
| Changes in pyridine metabolism profile during growth of trigonelline-forming Lotus japonicus cell cultures. | Phytochemistry 20081201 |
| [Vascular and renal effects of anti-angiogenic therapy]. | Nephrologie & therapeutique 20081201 |
| Chiral carboxylic acids and their effects on melting-point behaviour in co-crystals with isonicotinamide. | Acta crystallographica. Section B, Structural science 20081201 |
| Economic evaluation of sorafenib in the treatment of hepatocellular carcinoma in Canada. | Current medical research and opinion 20081201 |
| Anti-glypican 3 antibody as a potential antitumor agent for human liver cancer. | Cancer research 20081201 |
| Potential role of sorafenib in the treatment of acute myeloid leukemia. | Leukemia & lymphoma 20081201 |
| Generalised erythematous skin eruptions induced by sorafenib: cutaneous toxicity and treatment outcome. | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20081201 |
| Update on worldwide efforts to prevent type 1 diabetes. | Annals of the New York Academy of Sciences 20081201 |
| Antitumor effects of a combination of interferon-alpha and sorafenib on human renal carcinoma cell lines. | Biomedical research (Tokyo, Japan) 20081201 |
| The diagnostic importance of photosensitivity dermatoses in chronic alcoholism: report of two cases. | Dermatology online journal 20081115 |
| Evolution of systemic therapy of advanced hepatocellular carcinoma. | World journal of gastroenterology 20081114 |
| Structural basis for catalytic and inhibitory mechanisms of human prostaglandin reductase PTGR2. | Structure (London, England : 1993) 20081112 |
| Combined tyrosine and serine/threonine kinase inhibition by sorafenib prevents progression of experimental pulmonary hypertension and myocardial remodeling. | Circulation 20081111 |
| Tyrosine kinase inhibitors: can promising new therapy associated with cardiac toxicity strengthen the concept of teamwork? | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081110 |
| Cardiac toxicity of sunitinib and sorafenib in patients with metastatic renal cell carcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081110 |
| Nicotinamide restores cognition in Alzheimer's disease transgenic mice via a mechanism involving sirtuin inhibition and selective reduction of Thr231-phosphotau. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20081105 |
| Safety and pharmacokinetics of motesanib in combination with gemcitabine for the treatment of patients with solid tumours. | British journal of cancer 20081104 |
| Engineering cytochrome P450 enzymes for improved activity towards biomimetic 1,4-NADH cofactors. | Chembiochem : a European journal of chemical biology 20081103 |
| Ethyl-paraben and nicotinamide mixtures: apparent solubility, thermal behavior and X-ray structure of the 1:1 co-crystal. | Journal of pharmaceutical sciences 20081101 |
| Hand foot skin reaction in cancer patients treated with the multikinase inhibitors sorafenib and sunitinib. | Annals of oncology : official journal of the European Society for Medical Oncology 20081101 |
| Effect of the multitargeted tyrosine kinase inhibitors imatinib, dasatinib, sunitinib, and sorafenib on mitochondrial function in isolated rat heart mitochondria and H9c2 cells. | Toxicological sciences : an official journal of the Society of Toxicology 20081101 |
| Resveratrol, a natural phytoalexin, normalizes hyperglycemia in streptozotocin-nicotinamide induced experimental diabetic rats. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20081101 |
| Acute exacerbation of hemorrhagic rectocolitis during antiangiogenic therapy with sunitinib and sorafenib. | Annals of oncology : official journal of the European Society for Medical Oncology 20081101 |
| [Molecular basis of targeted therapy in metastatic renal cancer]. | Der Pathologe 20081101 |
| Effect of guava (Psidium guajava Linn.) leaf soluble solids on glucose metabolism in type 2 diabetic rats. | Phytotherapy research : PTR 20081101 |
| Systemic therapy of hepatocellular carcinoma: are we making progress? | Advances in therapy 20081101 |
| Systemic therapy for metastatic renal cell carcinoma. | The Urologic clinics of North America 20081101 |
| Sorafenib inhibits signal transducer and activator of transcription 3 signaling associated with growth arrest and apoptosis of medulloblastomas. | Molecular cancer therapeutics 20081101 |
| Identification and SAR around N-{2-[4-(2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1,4]diazepan-1-yl]-ethyl}-2-phenoxy-nicotinamide, a selective alpha2C adrenergic receptor antagonist. | Bioorganic & medicinal chemistry letters 20081015 |
| Design and synthesis of 6-phenylnicotinamide derivatives as antagonists of TRPV1. | Bioorganic & medicinal chemistry letters 20081015 |
| Sorafenib for older patients with renal cell carcinoma: subset analysis from a randomized trial. | Journal of the National Cancer Institute 20081015 |
| Phase II trial of sorafenib in advanced thyroid cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081010 |
| Effect of coadministration of ketoconazole, a strong CYP3A4 inhibitor, on pharmacokinetics and tolerability of motesanib diphosphate (AMG 706) in patients with advanced solid tumors. | Investigational new drugs 20081001 |
| [Targeted therapy for metastatic bladder cancer]. | Der Urologe. Ausg. A 20081001 |
| [Value of targeted therapies for renal cell cancer]. | Der Urologe. Ausg. A 20081001 |
| [Targeted therapy - point blank or single shot]. | Der Urologe. Ausg. A 20081001 |
| Preoperative tyrosine kinase inhibition as an adjunct to debulking nephrectomy. | Urology 20081001 |
| About sorafenib in castration-resistant prostate cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20081001 |
| Hypoxia inducible factor-1 alpha and vascular endothelial growth factor expression are associated with a poor prognosis in patients with nasopharyngeal carcinoma receiving radiotherapy with carbogen and nicotinamide. | Clinical oncology (Royal College of Radiologists (Great Britain)) 20081001 |
| Searching for the Achilles' heel of melanoma cells: new treatment modalities. | Pigment cell & melanoma research 20081001 |
| Sulphurous mineral water oral therapy: effects on erythrocyte metabolism. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20081001 |
| Maternal intake of fat, riboflavin and nicotinamide and the risk of having offspring with congenital heart defects. | European journal of nutrition 20081001 |
| Pnc1p-mediated nicotinamide clearance modifies the epigenetic properties of rDNA silencing in Saccharomyces cerevisiae. | Genetics 20081001 |
| Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation. | Cancer biology & therapy 20081001 |
| Novel drugs for renal cell carcinoma. | Expert opinion on investigational drugs 20081001 |
| Molecular targeted therapies in hepatocellular carcinoma. | Hepatology (Baltimore, Md.) 20081001 |
| Dynamic contrast-enhanced magnetic resonance imaging pharmacodynamic biomarker study of sorafenib in metastatic renal carcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081001 |
| [Systemic therapy of metastasizing renal cell carcinoma]. | Der Urologe. Ausg. A 20081001 |
| Recent advances in the treatment of renal cell carcinoma and the role of targeted therapies. | European journal of cancer (Oxford, England : 1990) 20081001 |
| Targeted therapies for metastatic renal cell carcinoma: an overview of toxicity and dosing strategies. | The oncologist 20081001 |
| Experimental study on inhibitory effect of niacinamide on tumor necrosis factor-alpha-induced matrix degradation of annulus fibrous tissue in vitro. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20081001 |
| Synthesis and evaluation of novel radioiodinated nicotinamides for malignant melanoma. | Nuclear medicine and biology 20081001 |
| Preclinical overview of sorafenib, a multikinase inhibitor that targets both Raf and VEGF and PDGF receptor tyrosine kinase signaling. | Molecular cancer therapeutics 20081001 |
| [Eruptive nevi associated with sorafenib treatment]. | Annales de dermatologie et de venereologie 20081001 |
| Age-related alterations of B-group vitamin contents in urine, blood and liver from rats. | Journal of nutritional science and vitaminology 20081001 |
| [Mechanism of apoptosis induced by SIRT1 deacetylase inhibitors in human breast cancer MCF-7 drug-resistant cells]. | Yao xue xue bao = Acta pharmaceutica Sinica 20081001 |
| Drug essentials. Small molecule multitargeted TKI therapy. | Oncology (Williston Park, N.Y.) 20081001 |
| Sunitinib-induced macrocytosis in patients with metastatic renal cell carcinoma. | Cancer 20080915 |
| Stimulation of muscle cell glucose uptake by resveratrol through sirtuins and AMPK. | Biochemical and biophysical research communications 20080912 |
| A SIR-tain acetyl complex is caught by a sulfur trap. | Structure (London, England : 1993) 20080910 |
| Major treatment improvements encourage kidney cancer researchers to seek further gains. | Journal of the National Cancer Institute 20080903 |
| Neoadjuvant targeted therapy and advanced kidney cancer: observations and implications for a new treatment paradigm. | BJU international 20080901 |
| Blockade of adenosine A2B receptors ameliorates murine colitis. | British journal of pharmacology 20080901 |
| Oesophageal variceal bleeding in hepatocellular carcinoma with portal vein thrombosis: improved outcome in response to molecular target therapy. | Clinical oncology (Royal College of Radiologists (Great Britain)) 20080901 |
| Targeted therapeutic approach for an anaplastic thyroid cancer in vitro and in vivo. | Cancer science 20080901 |
| Measuring the effects of topical moisturizers on changes in stratum corneum thickness, water gradients and hydration in vivo. | The British journal of dermatology 20080901 |
| von Hippel-Lindau gene status and response to vascular endothelial growth factor targeted therapy for metastatic clear cell renal cell carcinoma. | The Journal of urology 20080901 |
| A Kaposi's sarcoma complete clinical response after sorafenib administration. | Annals of oncology : official journal of the European Society for Medical Oncology 20080901 |
| Targeted therapy in renal cell carcinoma. | Current opinion in urology 20080901 |
| Vorinostat and sorafenib synergistically kill tumor cells via FLIP suppression and CD95 activation. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080901 |
| The formation of nicotinamide by administration of di(2-ethylhexyl)phthalate does not cause growth retardation in young rats in contrast with excess exogenous administration of nicotinamide. | Bioscience, biotechnology, and biochemistry 20080901 |
| Evolving strategies for the management of hand-foot skin reaction associated with the multitargeted kinase inhibitors sorafenib and sunitinib. | The oncologist 20080901 |
| Polarographic behavior of nicotinamide in surfactant media and its determination in cetyltrimethylammonium bromide surfactant system. | Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20080901 |
| [Renal cell carcinoma]. | Gan to kagaku ryoho. Cancer & chemotherapy 20080901 |
| [Anti-angiogenic treatment in the management of metastatic renal cell carcinoma]. | Bulletin du cancer 20080901 |
| [Tumor vasculature as a therapeutic target in non-small cell lung cancer]. | Magyar onkologia 20080901 |
| Matrix metaloproteinases activity during the evolution of hypoxic-ischemic brain damage in the immature rat. The effect of 1-methylnicotinamide (MNA). | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20080901 |
| Cutaneous drug eruptions induced by sorafenib: a case series. | Journal of drugs in dermatology : JDD 20080901 |
| Simultaneous determination of some water-soluble vitamins and preservatives in multivitamin syrup by validated stability-indicating high-performance liquid chromatography method. | Journal of chromatography. A 20080822 |
| Secondary erythrocytosis produced by the tyrosine kinase inhibitors sunitinib and sorafenib. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080820 |
| Novel histamine H3 receptor antagonists GSK189254 and GSK334429 are efficacious in surgically-induced and virally-induced rat models of neuropathic pain. | Pain 20080815 |
| Effect of rapamycin alone and in combination with sorafenib in an orthotopic model of human hepatocellular carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080815 |
| Watchdog set to reject four drugs for kidney cancer on the NHS. | BMJ (Clinical research ed.) 20080814 |
| Combined inhibition of MAPK and mTOR signaling inhibits growth, induces cell death, and abrogates invasive growth of melanoma cells. | The Journal of investigative dermatology 20080801 |
| ADP-ribosyl cyclase and ryanodine receptors mediate endothelin ETA and ETB receptor-induced renal vasoconstriction in vivo. | American journal of physiology. Renal physiology 20080801 |
| Nicotinamide attenuates aquaporin 3 overexpression induced by retinoic acid through inhibition of EGFR/ERK in cultured human skin keratinocytes. | International journal of molecular medicine 20080801 |
| Challenges and pitfalls of combining targeted agents in phase I studies. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080801 |
| Combination targeted therapy with sorafenib and bevacizumab results in enhanced toxicity and antitumor activity. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080801 |
| A phase I trial of the oral, multikinase inhibitor sorafenib in combination with carboplatin and paclitaxel. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080801 |
| Sorafenib potently inhibits papillary thyroid carcinomas harboring RET/PTC1 rearrangement. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080801 |
| Down-regulation of myeloid cell leukemia-1 through inhibiting Erk/Pin 1 pathway by sorafenib facilitates chemosensitization in breast cancer. | Cancer research 20080801 |
| Selected combination therapy with sorafenib: a review of clinical data and perspectives in advanced solid tumors. | The oncologist 20080801 |
| Broad neuroprotective profile of nicotinamide in different mouse models of MPTP-induced parkinsonism. | The European journal of neuroscience 20080801 |
| Effectively targeting BRAF in melanoma: a formidable challenge. | Pigment cell & melanoma research 20080801 |
| Contemporary management of hepatocellular carcinoma. | Clinical medicine (London, England) 20080801 |
| [A comparison on radiochemical behavior and biological property of antisense oligonucleotide labeled with technetium-99m by two methods: NHS-MAG3 versus SHNHP]. | Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20080801 |
| Sorafenib-induced liver failure. | The American journal of gastroenterology 20080801 |
| [Molecular targeted therapy for renal cell carcinoma]. | [Rinsho ketsueki] The Japanese journal of clinical hematology 20080801 |
| [Coadministration of sorafenib and cisplatin inhibits proliferation of hepatocellular carcinoma HepG2 cells in vitro]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20080801 |
| Medical therapies to extend survival in hepatocellular carcinoma. | Clinical advances in hematology & oncology : H&O 20080801 |
| Sorafenib in advanced hepatocellular carcinoma. | The New England journal of medicine 20080724 |
| Sorafenib in liver cancer--just the beginning. | The New England journal of medicine 20080724 |
| Electrophile-induced dearomatizing spirocyclization of N-arylisonicotinamides: a route to spirocyclic piperidines. | Organic letters 20080717 |
| [The 43rd Annual Meeting of the European Association for the Study of the Liver (EASL), Milan, Italy, April 23-27, 2008]. | Orvosi hetilap 20080713 |
| Efficacy of sunitinib and sorafenib in non-clear cell renal cell carcinoma: results from expanded access studies. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080710 |
| Aldehyde oxidase-catalyzed metabolism of N1-methylnicotinamide in vivo and in vitro in chimeric mice with humanized liver. | Drug metabolism and disposition: the biological fate of chemicals 20080701 |
| High doses of nicotinamide prevent oxidative mitochondrial dysfunction in a cellular model and improve motor deficit in a Drosophila model of Parkinson's disease. | Journal of neuroscience research 20080701 |
| A randomized, double-blind, placebo-controlled trial of niacinamide for reduction of phosphorus in hemodialysis patients. | Clinical journal of the American Society of Nephrology : CJASN 20080701 |
| Therapeutic potential of 1-methylnicotinamide against acute gastric lesions induced by stress: role of endogenous prostacyclin and sensory nerves. | The Journal of pharmacology and experimental therapeutics 20080701 |
| SIRT1, a longevity gene, downregulates angiotensin II type 1 receptor expression in vascular smooth muscle cells. | Arteriosclerosis, thrombosis, and vascular biology 20080701 |
| Phase I and pharmacokinetic study of sorafenib, an oral multikinase inhibitor, in Japanese patients with advanced refractory solid tumors. | Cancer science 20080701 |
| Surgical morbidity associated with administration of targeted molecular therapies before cytoreductive nephrectomy or resection of locally recurrent renal cell carcinoma. | The Journal of urology 20080701 |
| Design, synthesis, and evaluation of bisubstrate analog inhibitors of cholera toxin. | Bioorganic & medicinal chemistry letters 20080701 |
| Increased metal tolerance in Salix by nicotinamide and nicotinic acid. | Plant physiology and biochemistry : PPB 20080701 |
| Antidiabetic properties of the alcoholic extract of Sphaeranthus indicus in streptozotocin-nicotinamide diabetic rats. | The Journal of pharmacy and pharmacology 20080701 |
| Biomarkers of angiogenesis for the development of antiangiogenic therapies in oncology: tools or decorations? | Nature clinical practice. Oncology 20080701 |
| Perfusion MDCT enables early detection of therapeutic response to antiangiogenic therapy. | AJR. American journal of roentgenology 20080701 |
| Renal cell carcinoma: the translation of molecular biology into new treatments, new patient outcomes, and nursing implications. | Oncology nursing forum 20080701 |
| Metastatic melanoma: scientific rationale for sorafenib treatment and clinical results. | Onkologie 20080701 |
| [Regression of vena cava tumour thrombus in response to sorafenib]. | Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie 20080701 |
| A distinct cutaneous reaction to sorafenib and a multikinase inhibitor. | International journal of dermatology 20080701 |
| Prospective study of the cutaneous adverse effects of sorafenib, a novel multikinase inhibitor. | Archives of dermatology 20080701 |
| [Antiangiogenics: new therapeutic standards in metastatic kidney cancer]. | Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie 20080701 |
| Nicotinamide treatment induces behavioral recovery when administered up to 4 hours following cortical contusion injury in the rat. | Neuroscience 20080626 |
| Effects of nicotinamide supplementation on liver and serum contents of amino acids in diabetic rats. | European journal of medical research 20080624 |
| Sorafenib, but not sunitinib, affects function of dendritic cells and induction of primary immune responses. | Blood 20080615 |
| Resolution of macular oedema in occult choroidal neovascularization under oral Sorafenib treatment. | Acta ophthalmologica 20080601 |
| Association of nicotinamide with parabens: effect on solubility, partition and transdermal permeation. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20080601 |
| Sorafenib inhibits activation of human peripheral blood T cells by targeting LCK phosphorylation. | Leukemia 20080601 |
| Metastatic chest wall malignant schwannoma responding to sorafenib: case report and literature review. | Cancer biology & therapy 20080601 |
| Aminoguanidine prevents the impairment of cardiac pumping mechanics in rats with streptozotocin and nicotinamide-induced type 2 diabetes. | British journal of pharmacology 20080601 |
| Eight-fold increased risk for congenital heart defects in children carrying the nicotinamide N-methyltransferase polymorphism and exposed to medicines and low nicotinamide. | European heart journal 20080601 |
| Prevention of type 1 diabetes: the time has come. | Nature clinical practice. Endocrinology & metabolism 20080601 |
| Effect of succinic acid monoethyl ester on hemoglobin glycation and tail tendon collagen properties in type 2 diabetic rats. | Fundamental & clinical pharmacology 20080601 |
| Linear and cyclic peptides from the entomopathogenic bacterium Xenorhabdus nematophilus. | Journal of natural products 20080601 |
| Early clinical studies of novel therapies for thyroid cancers. | Endocrinology and metabolism clinics of North America 20080601 |
| Targeted therapy in advanced non-small-cell lung cancer. | Seminars in respiratory and critical care medicine 20080601 |
| Combining nanoliposomal ceramide with sorafenib synergistically inhibits melanoma and breast cancer cell survival to decrease tumor development. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080601 |
| Sorafenib in lung cancer: clinical developments and future directions. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20080601 |
| K-ras as a target for lung cancer therapy. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20080601 |
| [Oncology 2008]. | Deutsche medizinische Wochenschrift (1946) 20080601 |
| Multiple squamous cell carcinomas of the skin after therapy with sorafenib combined with tipifarnib. | Archives of dermatology 20080601 |
| Sorafenib-induced eruptive melanocytic lesions. | Archives of dermatology 20080601 |
| Sorafenib-induced palmoplantar hyperkeratosis. | Journal of drugs in dermatology : JDD 20080601 |
| Reader seeks clarification on hand-foot skin reaction. | Clinical journal of oncology nursing 20080601 |
| 18F-Fluorodeoxyglucose positron emission tomography for monitoring response to sorafenib treatment in patients with hepatocellular carcinoma. | The oncologist 20080601 |
| Cytoprotective effects of nicotinamide derivatives in endothelial cells. | Nucleosides, nucleotides & nucleic acids 20080601 |
| [Lung cancer]. | Medizinische Klinik (Munich, Germany : 1983) 20080515 |
| Bowel perforation after radiotherapy in a patient receiving sorafenib. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080510 |
| Toxicities associated with the administration of sorafenib, sunitinib, and temsirolimus and their management in patients with metastatic renal cell carcinoma. | European urology 20080501 |
| Re: damien pouessel, stéphane culine. High frequency of intracerebral hemorrhage in metastatic renal carcinoma patients with brain metastases treated with tyrosine kinase inhibitors targeting the vascular endothelial growth factor receptor. Eur urol 2008;53:376-81. | European urology 20080501 |
| Blocking transforming growth factor-beta up-regulates E-cadherin and reduces migration and invasion of hepatocellular carcinoma cells. | Hepatology (Baltimore, Md.) 20080501 |
| Alterations in kynurenine precursor and product levels in schizophrenia and bipolar disorder. | Neurochemistry international 20080501 |
| Nicorandil and ulcerations: a NAD/NADP and nicotinic acid-dependent side-effect? | The British journal of dermatology 20080501 |
| Renal cell carcinoma. | Current opinion in oncology 20080501 |
| Nicotinamide inhibits Plasmodium falciparum Sir2 activity in vitro and parasite growth. | FEMS microbiology letters 20080501 |
| Medullary thyroid cancer: targeting the RET kinase pathway with sorafenib/tipifarnib. | Molecular cancer therapeutics 20080501 |
| Double-blind randomized phase II study of the combination of sorafenib and dacarbazine in patients with advanced melanoma: a report from the 11715 Study Group. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080501 |
| Radiolabeled bombesin analogs for prostate cancer diagnosis: preclinical studies. | Nuclear medicine and biology 20080501 |
| Comparison of antitumor effects of multitargeted tyrosine kinase inhibitors in acute myelogenous leukemia. | Molecular cancer therapeutics 20080501 |
| Enzymology of mammalian NAD metabolism in health and disease. | Frontiers in bioscience : a journal and virtual library 20080501 |
| Transient downregulation of protein O-N-acetylglucosaminylation by treatment of high-dose nicotinamide in human cells. | Experimental & molecular medicine 20080430 |
| Genomic assessment of a multikinase inhibitor, sorafenib, in a rodent model of pulmonary hypertension. | Physiological genomics 20080422 |
| Lack of reliability of CA125 response criteria with anti-VEGF molecularly targeted therapy. | Cancer 20080415 |
| Anti-sense oligonucleotide labeled with technetium-99m using hydrazinonictinamide derivative and N-hydroxysuccinimidyl S-acetylmercaptoacetyltriglycline: a comparison of radiochemical behaviors and biological properties. | World journal of gastroenterology 20080414 |
| p53-, SIRT1-, and PARP-1-independent downregulation of p21WAF1 expression in nicotinamide-treated cells. | Biochemical and biophysical research communications 20080404 |
| Safety and anti-tumor activity of sorafenib (Nexavar) in combination with other anti-cancer agents: a review of clinical trials. | Cancer chemotherapy and pharmacology 20080401 |
| [Renal cell carcinoma and antiangiogenic therapies]. | Presse medicale (Paris, France : 1983) 20080401 |
| A phase II study of sorafenib in patients with chemo-naive castration-resistant prostate cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20080401 |
| Sorafenib induces apoptosis of AML cells via Bim-mediated activation of the intrinsic apoptotic pathway. | Leukemia 20080401 |
| Local production of O2- by NAD(P)H oxidase in the sarcoplasmic reticulum of coronary arterial myocytes: cADPR-mediated Ca2+ regulation. | Cellular signalling 20080401 |
| Pilot study of DCE-MRI to predict progression-free survival with sorafenib therapy in renal cell carcinoma. | Cancer biology & therapy 20080401 |
| Deoxymugineic acid increases Zn translocation in Zn-deficient rice plants. | Plant molecular biology 20080401 |
| Dramatic reduction of chronic lymphoedema of the lower limb with sorafenib therapy. | Melanoma research 20080401 |
| Chemotherapeutic agents and the skin: An update. | Journal of the American Academy of Dermatology 20080401 |
| 1-Methylnicotinamide and nicotinamide: two related anti-inflammatory agents that differentially affect the functions of activated macrophages. | Archivum immunologiae et therapiae experimentalis 20080401 |
| Mcl-1: a gateway to TRAIL sensitization. | Cancer research 20080401 |
| Sorafenib for metastatic renal cancer: the Princess Margaret experience. | American journal of clinical oncology 20080401 |
| Treatment options for metastatic renal cell carcinoma: a review. | The Canadian journal of urology 20080401 |
| Sorafenib inhibits growth and mitogen-activated protein kinase signaling in malignant peripheral nerve sheath cells. | Molecular cancer therapeutics 20080401 |
| [Inhibitory effect of sorafenib combined with arsenic trioxide on hepatocellular carcinoma cells]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20080401 |
| Saccharomyces cerevisiae YOR071C encodes the high affinity nicotinamide riboside transporter Nrt1. | The Journal of biological chemistry 20080328 |
| Re: Design of phase II cancer trials using a continuous endpoint of change in tumor size: application to a study of sorafenib and erlotinib in non-small cell lung cancer. | Journal of the National Cancer Institute 20080319 |
| Nicotinamide induces differentiation of embryonic stem cells into insulin-secreting cells. | Experimental cell research 20080310 |
| Compaction of lactose drug mixtures: quantification of the extent of incompatibility by FT-Raman spectroscopy. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20080301 |
| Poly(amido amine)s as gene delivery vectors: effects of quaternary nicotinamide moieties in the side chains. | ChemMedChem 20080301 |
| Hand-foot skin reaction in patients treated with sorafenib: a clinicopathological study of cutaneous manifestations due to multitargeted kinase inhibitor therapy. | The British journal of dermatology 20080301 |
| NAD+ and vitamin B3: from metabolism to therapies. | The Journal of pharmacology and experimental therapeutics 20080301 |
| Pharmacological control of secondary hyperparathyroidism in chronic hemodialysis patients: cinacalcet is coming to Japan. | Expert opinion on pharmacotherapy 20080301 |
| SIRT1 inhibition alleviates gene silencing in Fragile X mental retardation syndrome. | PLoS genetics 20080301 |
| New therapeutic directions for advanced pancreatic cancer: targeting the epidermal growth factor and vascular endothelial growth factor pathways. | The oncologist 20080301 |
| [Case of non-alcoholic pellagra following gastrectomy]. | Rinsho shinkeigaku = Clinical neurology 20080301 |
| Proper positioning of the nicotinamide ring is crucial for the Ascaris suum malic enzyme reaction. | Biochemistry 20080226 |
| [New drugs; sunitinib and sorafenib]. | Nederlands tijdschrift voor geneeskunde 20080223 |
| A preeclampsia-like syndrome characterized by reversible hypertension and proteinuria induced by the multitargeted kinase inhibitors sunitinib and sorafenib. | Journal of the National Cancer Institute 20080220 |
| Proper orientation of the nicotinamide ring of NADP is important for the precatalytic conformational change in the 6-phosphogluconate dehydrogenase reaction. | Biochemistry 20080219 |
| [Angiogenesis inhibitors for the systemic treatment of metastatic renal cell carcinoma: sunitinib, sorafenib, bevacizumab and temsirolimus]. | Nederlands tijdschrift voor geneeskunde 20080216 |
| Assessment of hypolipidaemic activity of three thiazolidin-4-ones in mice given high-fat diet and fructose. | Chemico-biological interactions 20080215 |
| Radiosterilization of drugs in aqueous solutions may be achieved by the use of radioprotective excipients. | International journal of pharmaceutics 20080212 |
| Examining heterogeneity in phase II trial designs may improve success in phase III. | Journal of the National Cancer Institute 20080206 |
| Mutant FLT3: a direct target of sorafenib in acute myelogenous leukemia. | Journal of the National Cancer Institute 20080206 |
| High frequency of intracerebral hemorrhage in metastatic renal carcinoma patients with brain metastases treated with tyrosine kinase inhibitors targeting the vascular endothelial growth factor receptor. | European urology 20080201 |
| UV radiation-induced immunosuppression is greater in men and prevented by topical nicotinamide. | The Journal of investigative dermatology 20080201 |
| Pancreatic scintigraphy with 99mTc-interleukin-2 at diagnosis of type 1 diabetes and after 1 year of nicotinamide therapy. | Diabetes/metabolism research and reviews 20080201 |
| Thyroid function test abnormalities in patients with metastatic renal cell carcinoma treated with sorafenib. | Annals of oncology : official journal of the European Society for Medical Oncology 20080201 |
| New developments in multitargeted therapy for patients with solid tumours. | Cancer treatment reviews 20080201 |
| Betacellulin and nicotinamide sustain PDX1 expression and induce pancreatic beta-cell differentiation in human embryonic stem cells. | Biochemical and biophysical research communications 20080201 |
| Topical nicotinamide prevents UV immunosuppression. | The Journal of investigative dermatology 20080201 |
| Adipose tissue failure and mitochondria as a possible target for improvement by bioactive food components. | Current opinion in lipidology 20080201 |
| Incidence and risk of hypertension with sorafenib in patients with cancer: a systematic review and meta-analysis. | The Lancet. Oncology 20080201 |
| Quantifying hypertension in patients with cancer treated with sorafenib. | The Lancet. Oncology 20080201 |
| Ranibizumab combined with low-dose sorafenib for exudative age-related macular degeneration. | Mayo Clinic proceedings 20080201 |
| FDA approves sorafenib for patients with inoperable liver cancer. | Gastroenterology 20080201 |
| Nicotinamide treatment provides acute neuroprotection and GFAP regulation following fluid percussion injury. | Journal of neurotrauma 20080201 |
| [Cutaneous side effects of sorafenib and sunitinib]. | Annales de dermatologie et de venereologie 20080201 |
| Development of a rapid and sensitive LC-MS/MS assay for the determination of sorafenib in human plasma. | Journal of pharmaceutical and biomedical analysis 20080122 |
| Development of sorafenib and other molecularly targeted agents in hepatocellular carcinoma. | Cancer 20080115 |
| Role of sunitinib and sorafenib in the treatment of metastatic renal cell carcinoma. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20080115 |
| Anti-inflammatory effect of 1-methylnicotinamide in contact hypersensitivity to oxazolone in mice; involvement of prostacyclin. | European journal of pharmacology 20080114 |
| GSK-3beta inhibition enhances sorafenib-induced apoptosis in melanoma cell lines. | The Journal of biological chemistry 20080111 |
| Molecular structure, vibrational spectra, quantum chemical calculations and photochemistry of picolinamide and isonicotinamide isolated in cryogenic inert matrixes and in the neat low-temperature solid phases. | The journal of physical chemistry. A 20080110 |
| Transformation products of extracellular NAD(+) in the rat liver: kinetics of formation and metabolic action. | Molecular and cellular biochemistry 20080101 |
| Modulation of Sirt1 by resveratrol and nicotinamide alters proliferation and differentiation of pig preadipocytes. | Molecular and cellular biochemistry 20080101 |
| Phase I study of sorafenib in Japanese patients with hepatocellular carcinoma. | Cancer science 20080101 |
| Insulin resistance and progression to type 1 diabetes in the European Nicotinamide Diabetes Intervention Trial (ENDIT). | Diabetes care 20080101 |
| Nicotinamide attenuates retinal ischemia and light insults to neurones. | Neurochemistry international 20080101 |
| Nitrate reductase assay for the rapid detection of pyrazinamide resistance in Mycobacterium tuberculosis using nicotinamide. | The Journal of antimicrobial chemotherapy 20080101 |
| Antitumor effects of sunitinib or sorafenib in patients with metastatic renal cell carcinoma who received prior antiangiogenic therapy. | The Journal of urology 20080101 |
| Nicotinamide metabolites accumulate in the tissues of uremic rats. | Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20080101 |
| Efficacy of sunitinib and sorafenib in metastatic papillary and chromophobe renal cell carcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080101 |
| A phase II clinical trial of sorafenib in androgen-independent prostate cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080101 |
| Sorafenib: in hepatocellular carcinoma. | Drugs 20080101 |
| Systematic review to establish the safety profiles for direct and indirect inhibitors of p38 Mitogen-activated protein kinases for treatment of cancer. A systematic review of the literature. | Medical oncology (Northwood, London, England) 20080101 |
| Risk of hand-foot skin reaction with sorafenib: a systematic review and meta-analysis. | Acta oncologica (Stockholm, Sweden) 20080101 |
| [Gastrointestinal stromal tumors: molecular aspects and therapeutic implications]. | Bulletin du cancer 20080101 |
| [News in digestive oncology]. | Bulletin du cancer 20080101 |
| [Molecular targeted therapy for renal cell carcinoma]. | Hinyokika kiyo. Acta urologica Japonica 20080101 |
| 1-Methylnicotinamide (MNA) prevents endothelial dysfunction in hypertriglyceridemic and diabetic rats. | Pharmacological reports : PR 20080101 |
| From single- to multi-target drugs in cancer therapy: when aspecificity becomes an advantage. | Current medicinal chemistry 20080101 |
| The role of angiogenesis inhibitors in prostate cancer. | Cancer journal (Sudbury, Mass.) 20080101 |
| Novel advancements in the management of hepatocellular carcinoma in 2008. | Journal of hepatology 20080101 |
| The role of NAD+ depletion in the mechanism of sulfur mustard-induced metabolic injury. | Cutaneous and ocular toxicology 20080101 |
| Pharmacodynamic monitoring of molecular-targeted agents in the peripheral blood of leukemia patients using flow cytometry. | Toxicologic pathology 20080101 |
| [Use of sorafenib (Nexavar) in the treatment of hepatocellular carcinoma: PRODIGE AFEF recommendations]. | Gastroenterologie clinique et biologique 20080101 |
| [Cutaneous side effects associated with epidermal growth factor receptor and tyrosine kinase inhibitors]. | Annales de dermatologie et de venereologie 20080101 |
| Triple play: promoting neurovascular longevity with nicotinamide, WNT, and erythropoietin in diabetes mellitus. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20080101 |
| Niacin and related compounds for treating hyperphosphatemia in dialysis patients. | Seminars in dialysis 20080101 |
| Neuroprotective effects of nicotinamide and 1-methylnicotinamide in acute excitotoxicity in vitro. | Folia neuropathologica 20080101 |
| Sorafenib, a systemic therapy for hepatocellular carcinoma. | Annals of hepatology 20080101 |
| Distinct efficacy of HIV-1 entry inhibitors to prevent cell-to-cell transfer of R5 and X4 viruses across a human placental trophoblast barrier in a reconstitution model in vitro. | Retrovirology 20080101 |
| Nicotinamide and 1-methylnicotinamide reduce homocysteine neurotoxicity in primary cultures of rat cerebellar granule cells. | Acta neurobiologiae experimentalis 20080101 |
| Nicotinic acid, nicotinamide, and nicotinamide riboside: a molecular evaluation of NAD+ precursor vitamins in human nutrition. | Annual review of nutrition 20080101 |
| Submerged culture mycelium and broth of Grifola frondosa improve glycemic responses in diabetic rats. | The American journal of Chinese medicine 20080101 |
| [The role of angiogenesis in renal carcinoma]. | Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20080101 |
| Characterization of rabbit ear skin as a skin model for in vitro transdermal permeation experiments: histology, lipid composition and permeability. | Skin pharmacology and physiology 20080101 |
| Metabolism of nicotinamide, adenine and inosine in developing microspore-derived canola (Brassica napus) embryos. | Plant physiology and biochemistry : PPB 20080101 |
| Time-resolved metabolomics reveals metabolic modulation in rice foliage. | BMC systems biology 20080101 |
| Effects of nicotinamide and riboflavin on the biodesulfurization activity of dibenzothiophene by Rhodococcus erythropolis USTB-03. | Journal of environmental sciences (China) 20080101 |
| Neoadjuvant therapy with sorafenib in advanced renal cell carcinoma with vena cava extension submitted to radical nephrectomy. | Urologia internationalis 20080101 |
| Comment on Di Silverio et al.: Neodajuvant therapy with sorafenib in advanced renal cell carcinoma with vena cava extension submitted to radical nephrectomy. Urol Int 2008;80:451-453. | Urologia internationalis 20080101 |
| An update on the medical therapy of advanced metastatic renal cell carcinoma. | Scandinavian journal of urology and nephrology 20080101 |
| Promising newer molecular-targeted therapies in head and neck cancer. | Drugs 20080101 |
| [New therapeutic regimes in metastasic renal-cell carcinoma]. | Der Internist 20080101 |
| Prospective comparison of sorafenib and sunitinib for second-line treatment of cytokine-refractory kidney cancer patients. | Oncology 20080101 |
| Sorafenib: tolerance in patients on chronic hemodialysis: a single-center experience. | Oncology 20080101 |
| Preclinical evaluation of dasatinib, a potent Src kinase inhibitor, in melanoma cell lines. | Journal of translational medicine 20080101 |
| Signaling inhibitors in metastatic renal cell carcinoma. | Cancer journal (Sudbury, Mass.) 20080101 |
| Sorafenib inhibits MAPK-mediated proliferation in a Barrett's esophageal adenocarcinoma cell line. | Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus 20080101 |
| Complete clinical response of metastatic hepatocellular carcinoma to sorafenib in a patient with hemochromatosis: a case report. | Journal of hematology & oncology 20080101 |
| Pathogenesis of ganglion 'cell death' in glaucoma and neuroprotection: focus on ganglion cell axonal mitochondria. | Progress in brain research 20080101 |
| [Correction of a reperfusion dysfunction in acute intestinal obstruction]. | Vestnik khirurgii imeni I. I. Grekova 20080101 |
| Thin-layer chromatography-densitometric measurements for determination of N-(hydroxymethyl)nicotinamide in tablets and stability evaluation in solutions. | Journal of AOAC International 20080101 |
| Localized palmar-plantar epidermal hyperplasia associated with use of sorafenib. | Clinical drug investigation 20080101 |
| Severe cutaneous reaction to sorafenib: induction of tolerance. | Acta dermato-venereologica 20080101 |
| Prospective, randomized, double-blind, multi-center, Phase III clinical study on transarterial chemoembolization (TACE) combined with Sorafenib versus TACE plus placebo in patients with hepatocellular cancer before liver transplantation - HeiLivCa [ISRCTN24081794]. | BMC cancer 20080101 |
| N-methylnicotinamide failed to induce endothelial prostacyclin release in perfused rat hindquarters. | Pharmacological reports : PR 20080101 |
| [The diagnosis and treatment of pulmonary hyperhydration in critically ill patients with acute poisoning by neurotropic agents]. | Anesteziologiia i reanimatologiia 20080101 |
| Beneficial effects of nicotinamide on alcohol-induced liver injury in senescence-accelerated mice. | BioFactors (Oxford, England) 20080101 |
| Variation in chronic nicotinamide treatment after traumatic brain injury can alter components of functional recovery independent of histological damage. | Oxidative medicine and cellular longevity 20080101 |
| [New drugs; sunitinib and sorafenib]. | Nederlands tijdschrift voor geneeskunde 20071229 |
| Identification of a new nicotinamide binding site in a sirtuin: a reassessment. | Molecular cell 20071228 |
| Syntheses of nicotinamide riboside and derivatives: effective agents for increasing nicotinamide adenine dinucleotide concentrations in mammalian cells. | Journal of medicinal chemistry 20071227 |
| Acetyl-lysine analog peptides as mechanistic probes of protein deacetylases. | The Journal of biological chemistry 20071221 |
| Mechanism-based inhibition of Sir2 deacetylases by thioacetyl-lysine peptide. | Biochemistry 20071218 |
| A clinical phase II study with sorafenib in patients with progressive hormone-refractory prostate cancer: a study of the CESAR Central European Society for Anticancer Drug Research-EWIV. | British journal of cancer 20071203 |
| 1-Methylnicotinamide stimulates cell growth and inhibits hemoglobin synthesis in differentiating murine erythroleukemia cells. | Toxicology in vitro : an international journal published in association with BIBRA 20071201 |
| Beneficial effect of heme oxygenase-1 expression on myocardial ischemia-reperfusion involves an increase in adiponectin in mildly diabetic rats. | American journal of physiology. Heart and circulatory physiology 20071201 |
| Influence of tetrahydrocurcumin on tail tendon collagen contents and its properties in rats with streptozotocin-nicotinamide-induced type 2 diabetes. | Fundamental & clinical pharmacology 20071201 |
| Co-acquisition of hyperpolarised 13C and 15N NMR spectra. | Magnetic resonance in chemistry : MRC 20071201 |
| The clinical anti-aging effects of topical kinetin and niacinamide in Asians: a randomized, double-blind, placebo-controlled, split-face comparative trial. | Journal of cosmetic dermatology 20071201 |
| Hepatocellular carcinoma: the role of the North American GI Steering Committee Hepatobiliary Task Force and the advent of effective drug therapy. | The oncologist 20071201 |
| Nicotinamide in dermatology: a capsule summary. | International journal of dermatology 20071201 |
| Uncovering Pandora's vase: the growing problem of new toxicities from novel anticancer agents. The case of sorafenib and sunitinib. | Clinical and experimental medicine 20071201 |
| Case reports: new onset flushing due to unauthorized substitution of niacin for nicotinamide. | Journal of drugs in dermatology : JDD 20071201 |
| FLT3 kinase inhibitors in the management of acute myeloid leukemia. | Clinical lymphoma & myeloma 20071201 |
| The direct involvement of SirT1 in insulin-induced insulin receptor substrate-2 tyrosine phosphorylation. | The Journal of biological chemistry 20071123 |
| The oncoprotein gankyrin interacts with RelA and suppresses NF-kappaB activity. | Biochemical and biophysical research communications 20071123 |
| Optimization of boron neutron capture therapy for the treatment of undifferentiated thyroid cancer. | International journal of radiation oncology, biology, physics 20071115 |
| SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation. | Nature 20071115 |
| Investigation of the molecular mechanisms preceding PDE4 inhibitor-induced vasculopathy in rats: tissue inhibitor of metalloproteinase 1, a potential predictive biomarker. | Toxicological sciences : an official journal of the Society of Toxicology 20071101 |
| Functional characterization of testis-specific rodent multidrug and toxic compound extrusion 2, a class III MATE-type polyspecific H+/organic cation exporter. | American journal of physiology. Cell physiology 20071101 |
| Plasmodium falciparum Sir2: an unusual sirtuin with dual histone deacetylase and ADP-ribosyltransferase activity. | Eukaryotic cell 20071101 |
| Discovery of N-phenyl nicotinamides as potent inhibitors of Kdr. | Bioorganic & medicinal chemistry letters 20071101 |
| Playing only one instrument may be not enough: limitations and future of the antiangiogenic treatment of cancer. | BioEssays : news and reviews in molecular, cellular and developmental biology 20071101 |
| Increased cardiotoxicity of sorafenib in sunitinib-pretreated patients with metastatic renal cell carcinoma. | Annals of oncology : official journal of the European Society for Medical Oncology 20071101 |
| Reduction of oxidative stress by a new low-molecular-weight antioxidant improves metabolic alterations in a nonobese mouse diabetes model. | Pancreas 20071101 |
| [Determination of nicotinamide in formula milk powder using liquid chromatography-isotope dilution mass spectrometry]. | Se pu = Chinese journal of chromatography 20071101 |
| Effect of cerebronorm on energy metabolism and lipid peroxidation in rat brain during hypoxia. | Bulletin of experimental biology and medicine 20071101 |
| Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity. | Molecular cell 20071026 |
| Complete response in a cutaneous facial metastatic nodule from renal cell carcinoma after hypofractionated radiotherapy. | Dermatology online journal 20071013 |
| Mcl-1 as a buffer for proapoptotic Bcl-2 family members during TRAIL-induced apoptosis: a mechanistic basis for sorafenib (Bay 43-9006)-induced TRAIL sensitization. | The Journal of biological chemistry 20071012 |
| Sorafenib functions to potently suppress RET tyrosine kinase activity by direct enzymatic inhibition and promoting RET lysosomal degradation independent of proteasomal targeting. | The Journal of biological chemistry 20071005 |
| Analysis of flonicamid and its metabolites in dried hops by liquid chromatography-tandem mass spectrometry. | Journal of agricultural and food chemistry 20071003 |
| Design of phase II cancer trials using a continuous endpoint of change in tumor size: application to a study of sorafenib and erlotinib in non small-cell lung cancer. | Journal of the National Cancer Institute 20071003 |
| Vitamin transport and homeostasis in mammalian brain: focus on Vitamins B and E. | Journal of neurochemistry 20071001 |
| Flonicamid, a novel insecticide with a rapid inhibitory effect on aphid feeding. | Pest management science 20071001 |
| A novel oral indoline-sulfonamide agent, N-[1-(4-methoxybenzenesulfonyl)-2,3-dihydro-1H-indol-7-yl]-isonicotinamide (J30), exhibits potent activity against human cancer cells in vitro and in vivo through the disruption of microtubule. | The Journal of pharmacology and experimental therapeutics 20071001 |
| GLUT2 protein at the rat proximal tubule brush border membrane correlates with protein kinase C (PKC)-betal and plasma glucose concentration. | Diabetologia 20071001 |
| Assimilation of NAD(+) precursors in Candida glabrata. | Molecular microbiology 20071001 |
| The effect of resveratrol on a cell model of human aging. | Annals of the New York Academy of Sciences 20071001 |
| Influence of tetrahydrocurcumin on hepatic and renal functional markers and protein levels in experimental type 2 diabetic rats. | Basic & clinical pharmacology & toxicology 20071001 |
| Sensitivity toward sorafenib and sunitinib varies between different activating and drug-resistant FLT3-ITD mutations. | Experimental hematology 20071001 |
| Managing side effects of angiogenesis inhibitors in renal cell carcinoma. | Onkologie 20071001 |
| Cell cycle dependent and schedule-dependent antitumor effects of sorafenib combined with radiation. | Cancer research 20071001 |
| The multikinase inhibitor sorafenib potentiates TRAIL lethality in human leukemia cells in association with Mcl-1 and cFLIPL down-regulation. | Cancer research 20071001 |
| Phase II study to investigate the efficacy, safety, and pharmacokinetics of sorafenib in Japanese patients with advanced renal cell carcinoma. | Japanese journal of clinical oncology 20071001 |
| Sorafenib: a promising new targeted therapy for renal cell carcinoma. | Clinical journal of oncology nursing 20071001 |
| Localized palmar-plantar epidermal hyperplasia: a previously undefined dermatologic toxicity to sorafenib. | The oncologist 20071001 |
| [Acute lymphoblastic leukemia with Philadelphia chromosome: treatment with kinase inhibitors]. | Bulletin du cancer 20071001 |
| Sorafenib TARGET trial results in Spanish patients. | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20071001 |
| Metabolic fate of nicotinamide in higher plants. | Physiologia plantarum 20071001 |
| New therapies in renal cell carcinoma. | Current opinion in supportive and palliative care 20071001 |
| Histone deacetylase inhibitor MS-275 alone or combined with bortezomib or sorafenib exhibits strong antiproliferative action in human cholangiocarcinoma cells. | World journal of gastroenterology 20070907 |
| The comparative bioavailability of an extended-release niacin and lovastatin fixed dose combination tablet versus extended-release niacin tablet, lovastatin tablet and a combination of extended-release niacin tablet and lovastatin tablet. | Biopharmaceutics & drug disposition 20070901 |
| Re: Börje Ljungberg, Damian C. Hanbury, Marcus A. Kuczyk, Axel S. Merseburger, Peter F.A. Mulders, Jean-Jaques Patard and Ioanel C. Sinescu. Renal cell cacinoma guideline. Eur Urol 2007;51:1502-10. | European urology 20070901 |
| The multikinase inhibitor sorafenib induces apoptosis in highly imatinib mesylate-resistant bcr/abl+ human leukemia cells in association with signal transducer and activator of transcription 5 inhibition and myeloid cell leukemia-1 down-regulation. | Molecular pharmacology 20070901 |
| 1-Methylnicotinamide (MNA), a primary metabolite of nicotinamide, exerts anti-thrombotic activity mediated by a cyclooxygenase-2/prostacyclin pathway. | British journal of pharmacology 20070901 |
| [Application monitoring of the use of sorafenib in papillary renal cell carcinoma]. | Der Urologe. Ausg. A 20070901 |
| Characterization of tumor specimens for a targeted therapy in metastatic renal cell carcinoma patients. | Current oncology reports 20070901 |
| Treatment options in renal cell carcinoma: past, present and future. | Annals of oncology : official journal of the European Society for Medical Oncology 20070901 |
| Hexakis[3-(aminocarbonyl)pyridinium] decavanadate(V) dihydrate. | Acta crystallographica. Section C, Crystal structure communications 20070901 |
| Renal cell cancer presented with leptomeningeal carcinomatosis effectively treated with sorafenib. | Onkologie 20070901 |
| Niacinamide abrogates the organ dysfunction and acute lung injury caused by endotoxin. | Journal of cardiovascular pharmacology 20070901 |
| Safety and tolerability of sorafenib in clear-cell renal cell carcinoma: a Phase III overview. | Expert review of anticancer therapy 20070901 |
| Acute pancreatitis associated with sorafenib. | Southern medical journal 20070901 |
| N-methylnicotinamide inhibits arterial thrombosis in hypertensive rats. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20070901 |
| Sunitinib, sorafenib and mTOR inhibitors in renal cancer. | Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20070901 |
| Mechanistic implications of the cysteine-nicotinamide adduct in aldehyde dehydrogenase based on quantum mechanical/molecular mechanical simulations. | Biochemistry 20070821 |
| Phase II trial of sorafenib in patients with recurrent or metastatic squamous cell carcinoma of the head and neck or nasopharyngeal carcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070820 |
| Beneficial effect of succinic acid monoethyl ester on erythrocyte membrane bound enzymes and antioxidant status in streptozotocin-nicotinamide induced type 2 diabetes. | Chemico-biological interactions 20070815 |
| Phase I targeted combination trial of sorafenib and erlotinib in patients with advanced solid tumors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070815 |
| Sorafenib inhibits the imatinib-resistant KITT670I gatekeeper mutation in gastrointestinal stromal tumor. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070815 |
| Adjuvant therapy with sorafenib in bone metastases bilateral renal carcinoma: a case report. | European urology 20070801 |
| Interstitial nephritis in a patient taking sorafenib. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070801 |
| Nicotinamide abrogates acute lung injury caused by ischaemia/reperfusion. | The European respiratory journal 20070801 |
| The kinase inhibitor sorafenib induces cell death through a process involving induction of endoplasmic reticulum stress. | Molecular and cellular biology 20070801 |
| Clinical factors associated with outcome in patients with metastatic clear-cell renal cell carcinoma treated with vascular endothelial growth factor-targeted therapy. | Cancer 20070801 |
| Nicotinamidase activity is important for germination. | The Plant journal : for cell and molecular biology 20070801 |
| Combination of radiofrequency ablation with antiangiogenic therapy for tumor ablation efficacy: study in mice. | Radiology 20070801 |
| SIRT1 activation confers neuroprotection in experimental optic neuritis. | Investigative ophthalmology & visual science 20070801 |
| Sorafenib and sunitinib: novel targeted therapies for renal cell cancer. | Pharmacotherapy 20070801 |
| Phase II trial of sorafenib plus interferon alfa-2b as first- or second-line therapy in patients with metastatic renal cell cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070801 |
| Sorafenib with interferon alfa-2b as first-line treatment of advanced renal carcinoma: a phase II study of the Southwest Oncology Group. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070801 |
| American Society of Clinical Oncology--43rd annual meeting. Translating research into practice. | IDrugs : the investigational drugs journal 20070801 |
| PET imaging of infection with a HYNIC-conjugated LTB4 antagonist labeled with F-18 via hydrazone formation. | Nuclear medicine and biology 20070801 |
| [The hepatocellular carcinoma: alternative therapeutical strategies]. | Zentralblatt fur Chirurgie 20070801 |
| Plasma and urine pharmacokinetics of niacin and its metabolites from an extended-release niacin formulation. | International journal of clinical pharmacology and therapeutics 20070801 |
| Neoadjuvant therapy for hepatocellular carcinoma: is there an optimal approach? | Oncology (Williston Park, N.Y.) 20070801 |
| [Intervention of nicotinamide on skin melanin genesis after UVA exposed]. | Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20070801 |
| Cancer drug trials show modest benefit: drugs target liver, gastric, head and neck cancers. | JAMA 20070718 |
| Synergistic interactions between vorinostat and sorafenib in chronic myelogenous leukemia cells involve Mcl-1 and p21CIP1 down-regulation. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070715 |
| Double resistance to imatinib and AMG 706 caused by multiple acquired KIT exon 17 mutations in a gastrointestinal stromal tumour. | Gut 20070701 |
| CCR drug updates: sorafenib and sunitinib in renal cell carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070701 |
| Reduction of TRAIL-induced Mcl-1 and cIAP2 by c-Myc or sorafenib sensitizes resistant human cancer cells to TRAIL-induced death. | Cancer cell 20070701 |
| Sorafenib [corrected] in kidney cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20070701 |
| [Interdisciplinary recommendations on targeted therapy in the treatment of renal cell carcinoma]. | Aktuelle Urologie 20070701 |
| [Oral drugs inhibiting the VEGF pathway]. | Bulletin du cancer 20070701 |
| [Angiogenesis and renal cell carcinoma]. | Bulletin du cancer 20070701 |
| [Cutaneous side effects of antiangiogenic agents]. | Bulletin du cancer 20070701 |
| Effect of nicotinamide administration on the tryptophan-nicotinamide pathway in humans. | International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20070701 |
| Targeting ELF in therapy of liver cancer. | Cancer biology & therapy 20070701 |
| Mechanisms of adverse effects of anti-VEGF therapy for cancer. | British journal of cancer 20070618 |
| 'Seed' analysis of off-target siRNAs reveals an essential role of Mcl-1 in resistance to the small-molecule Bcl-2/Bcl-XL inhibitor ABT-737. | Oncogene 20070607 |
| Plasticity of basal ganglia neurocircuitries following perinatal asphyxia: effect of nicotinamide. | Experimental brain research 20070601 |
| GSK189254, a novel H3 receptor antagonist that binds to histamine H3 receptors in Alzheimer's disease brain and improves cognitive performance in preclinical models. | The Journal of pharmacology and experimental therapeutics 20070601 |
| ASCO 2006 highlights: targeted therapy for renal cell carcinoma. | Cancer treatment reviews 20070601 |
| Soraprazan: setting new standards in inhibition of gastric acid secretion. | The Journal of pharmacology and experimental therapeutics 20070601 |
| PARP inhibition reduces acute colonic inflammation in rats. | European journal of pharmacology 20070601 |
| A nuclear magnetic resonance-based functional assay for nicotinamide adenine dinucleotide synthetase. | Journal of biomolecular screening 20070601 |
| Combined targeting of MAPK and AKT signalling pathways is a promising strategy for melanoma treatment. | The British journal of dermatology 20070601 |
| Effect of the rate of niacin administration on the plasma and urine pharmacokinetics of niacin and its metabolites. | Journal of clinical pharmacology 20070601 |
| Escape of HIV-1 from a small molecule CCR5 inhibitor is not associated with a fitness loss. | PLoS pathogens 20070601 |
| Sorafenib inhibits imatinib-resistant KIT and platelet-derived growth factor receptor beta gatekeeper mutants. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070601 |
| Effects of sorafenib on symptoms and quality of life: results from a large randomized placebo-controlled study in renal cancer. | American journal of clinical oncology 20070601 |
| Sorafenib inhibits the angiogenesis and growth of orthotopic anaplastic thyroid carcinoma xenografts in nude mice. | Molecular cancer therapeutics 20070601 |
| Protein kinase inhibitors in the treatment of renal cell carcinoma: sorafenib. | Annals of oncology : official journal of the European Society for Medical Oncology 20070601 |
| Can sorafenib cause hypothyroidism? | Journal of chemotherapy (Florence, Italy) 20070601 |
| B-Raf kinase inhibitors for cancer treatment. | Current opinion in investigational drugs (London, England : 2000) 20070601 |
| Scriptaid and suberoylanilide hydroxamic acid are histone deacetylase inhibitors with potent anti-Toxoplasma gondii activity in vitro. | The Journal of parasitology 20070601 |
| ASCO 2007: plenary top 5. | Oncology (Williston Park, N.Y.) 20070601 |
| [Synthesis and study on the interaction of rare earth complexes of N', N-bis(2-pyridinecarboxamide)-1, 2-ethane with DNA]. | Guang pu xue yu guang pu fen xi = Guang pu 20070601 |
| [Promising new treatment options for metastatic androgen-independent prostate cancer]. | Actas urologicas espanolas 20070601 |
| [Niacin in therapy]. | Postepy higieny i medycyny doswiadczalnej (Online) 20070515 |
| Stacking complexation by nicotinamide: a useful way of enhancing drug solubility. | International journal of pharmaceutics 20070504 |
| Sustained release of hydrophobic and hydrophilic drugs from a floating dosage form. | International journal of pharmaceutics 20070504 |
| Vitamins and aging: pathways to NAD+ synthesis. | Cell 20070504 |
| Nicotinamide riboside promotes Sir2 silencing and extends lifespan via Nrk and Urh1/Pnp1/Meu1 pathways to NAD+. | Cell 20070504 |
| [Chronic lymphocytic leukemia and loss of strength in the right arm--not a typical combination]. | Praxis 20070502 |
| Sorafenib alone or as combination therapy for growth control of cholangiocarcinoma. | Biochemical pharmacology 20070501 |
| Repression of inflammatory gene expression in human pulmonary epithelial cells by small-molecule IkappaB kinase inhibitors. | The Journal of pharmacology and experimental therapeutics 20070501 |
| Prediction and prevention of type 1 diabetes: progress, problems, and prospects. | Clinical pharmacology and therapeutics 20070501 |
| [Efficacy of multikinase inhibitors in the treatment of advanced renal cell cancer. A snapshot]. | Der Urologe. Ausg. A 20070501 |
| Genetic basis of kidney cancer: a model for developing molecular-targeted therapies. | BJU international 20070501 |
| Crystallization pathways and kinetics of carbamazepine-nicotinamide cocrystals from the amorphous state by in situ thermomicroscopy, spectroscopy, and calorimetry studies. | Journal of pharmaceutical sciences 20070501 |
| Combination of target agents: challenges and opportunities. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20070501 |
| Molecular mechanisms of cardiotoxicity of tyrosine kinase inhibition. | Nature reviews. Cancer 20070501 |
| Angiogenesis in cancer: molecular mechanisms, clinical impact. | Langenbeck's archives of surgery 20070501 |
| Do the results of the new trials change the standard treatment of metastatic renal cell cancer? | Onkologie 20070501 |
| Niacin nutritional status in HIV type 1-positive children: preliminary data. | Journal of pediatric gastroenterology and nutrition 20070501 |
| Phase I trial of sorafenib in combination with gefitinib in patients with refractory or recurrent non-small cell lung cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070501 |
| Sorafenib: delivering a targeted drug to the right targets. | Expert review of anticancer therapy 20070501 |
| A randomized phase II study of sorafenib/gemcitabine or sorafenib/erlotinib for advanced non-small-cell lung cancer in elderly patients or patients with a performance status of 2: treatment rationale and protocol dynamics. | Clinical lung cancer 20070501 |
| Vascular endothelial growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer: a review of recent clinical trials. | Reviews on recent clinical trials 20070501 |
| A metabolomic comparison of urinary changes in type 2 diabetes in mouse, rat, and human. | Physiological genomics 20070424 |
| Initial-rate kinetics of human NMN-adenylyltransferases: substrate and metal ion specificity, inhibition by products and multisubstrate analogues, and isozyme contributions to NAD+ biosynthesis. | Biochemistry 20070424 |
| Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha. | The EMBO journal 20070404 |
| Sorafenib (BAY 43-9006) inhibits tumor growth and vascularization and induces tumor apoptosis and hypoxia in RCC xenograft models. | Cancer chemotherapy and pharmacology 20070401 |
| The Caenorhabditis elegans nicotinamidase PNC-1 enhances survival. | Mechanisms of ageing and development 20070401 |
| Developmental changes of aldehyde oxidase activity in young Japanese children. | Clinical pharmacology and therapeutics 20070401 |
| [Clinical studies with sorafenib (Nexavar) in metastatic melanoma]. | Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20070401 |
| Oxidative stress induces p53-dependent apoptosis in hepatoblastoma cell through its nuclear translocation. | Genes to cells : devoted to molecular & cellular mechanisms 20070401 |
| Mutant V600E BRAF increases hypoxia inducible factor-1alpha expression in melanoma. | Cancer research 20070401 |
| Pulmonary blastoma with renal metastasis responds to sorafenib. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20070401 |
| Sorafenib-induced pancreatitis. | Mayo Clinic proceedings 20070401 |
| Pharmacological targeting of IDO-mediated tolerance for treating autoimmune disease. | Current drug metabolism 20070401 |
| Safety, pharmacokinetics, and preliminary antitumor activity of sorafenib: a review of four phase I trials in patients with advanced refractory solid tumors. | The oncologist 20070401 |
| Design of clinical trials of radiation combined with antiangiogenic therapy. | The oncologist 20070401 |
| Developmental changes of aldehyde oxidase in postnatal rat liver. | Drug metabolism and pharmacokinetics 20070401 |
| The effect of recent drug approvals on translational research and drug development. | Clinical advances in hematology & oncology : H&O 20070401 |
| Nicotinamide inhibits B lymphocyte activation by disrupting MAPK signal transduction. | Biochemical pharmacology 20070315 |
| A regenerable ruthenium tetraammine nitrosyl complex immobilized on a modified silica gel surface: preparation and studies of nitric oxide release and nitrite-to-NO conversion. | Journal of colloid and interface science 20070315 |
| Discovery and SAR of isonicotinamide BACE-1 inhibitors that bind beta-secretase in a N-terminal 10s-loop down conformation. | Bioorganic & medicinal chemistry letters 20070315 |
| Phase I trial of sorafenib in combination with IFN alpha-2a in patients with unresectable and/or metastatic renal cell carcinoma or malignant melanoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070315 |
| Nicotinamide prevents the effect of perinatal asphyxia on dopamine release evaluated with in vivo microdialysis 3 months after birth. | Experimental brain research 20070301 |
| Antitumor activity of sorafenib in FLT3-driven leukemic cells. | Leukemia 20070301 |
| Changes in glycoprotein components in streptozotocin--nicotinamide induced type 2 diabetes: influence of tetrahydrocurcumin from Curcuma longa. | Plant foods for human nutrition (Dordrecht, Netherlands) 20070301 |
| Sorafenib-induced erythema multiforme. | Journal of the American Academy of Dermatology 20070301 |
| Drug insight: VEGF as a therapeutic target for breast cancer. | Nature clinical practice. Oncology 20070301 |
| NAD(P)H:quinone oxidoreductase 1 and nrh:quinone oxidoreductase 2 activity and expression in bladder and ovarian cancer and lower NRH:quinone oxidoreductase 2 activity associated with an NQO2 exon 3 single-nucleotide polymorphism. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070301 |
| Nicotinamidase participates in the salvage pathway of NAD biosynthesis in Arabidopsis. | The Plant journal : for cell and molecular biology 20070301 |
| Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine. | Journal of cosmetic dermatology 20070301 |
| Yellow skin discoloration associated with sorafenib use for treatment of metastatic renal cell carcinoma. | Southern medical journal 20070301 |
| Radiation therapy and sorafenib: clinical data and rationale for the combination in metastatic renal cell carcinoma. | Clinical genitourinary cancer 20070301 |
| Two new drugs for renal cell carcinoma. | The Medical letter on drugs and therapeutics 20070226 |
| Resveratrol protects dopaminergic neurons in midbrain slice culture from multiple insults. | Biochemical pharmacology 20070215 |
| Vascular endothelial growth factor-targeted therapy in renal cell carcinoma: current status and future directions. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070215 |
| Structural basis for nicotinamide inhibition and base exchange in Sir2 enzymes. | Molecular cell 20070209 |
| Sorafenib is efficacious and tolerated in combination with cytotoxic or cytostatic agents in preclinical models of human non-small cell lung carcinoma. | Cancer chemotherapy and pharmacology 20070201 |
| A rapid and sensitive method for determination of sorafenib in human plasma using a liquid chromatography/tandem mass spectrometry assay. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070201 |
| The effects of calcitriol and nicotinamide on residual pancreatic beta-cell funtion in patients with recent-onset Type 1 diabetes (IMDIAB XI). | Diabetic medicine : a journal of the British Diabetic Association 20070201 |
| New drugs 07, part I. | Nursing 20070201 |
| American Society of Hematology--48th Annual Meeting and Exposition. Updates on therapies. 9-12 December 2006 Orlando, FL, USA. | IDrugs : the investigational drugs journal 20070201 |
| Sorafenib and sunitinib in the treatment of advanced non-small cell lung cancer. | The oncologist 20070201 |
| Protective effect of niacinamide on interleukin-1beta-induced annulus fibrosus type II collagen degeneration in vitro. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20070201 |
| [Clinical results of Nexavar for the treatment of kidney cancer]. | Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie 20070201 |
| Role of anti-angiogenesis agents in treating NSCLC: focus on bevacizumab and VEGFR tyrosine kinase inhibitors. | Current treatment options in oncology 20070201 |
| Hand-foot and stump syndrome to sorafenib. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070120 |
| Sorafenib in renal cell carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070115 |
| Sorafenib in advanced clear-cell renal-cell carcinoma. | The New England journal of medicine 20070111 |
| Renal-cell carcinoma--molecular pathways and therapies. | The New England journal of medicine 20070111 |
| Combining high-performance liquid chromatography with on-line microdialysis sampling for the simultaneous determination of ascorbyl glucoside, kojic acid, and niacinamide in bleaching cosmetics. | Analytica chimica acta 20070102 |
| Endothelin-A and -B receptors, superoxide, and Ca2+ signaling in afferent arterioles. | American journal of physiology. Renal physiology 20070101 |
| SIRT1 interacts with p73 and suppresses p73-dependent transcriptional activity. | Journal of cellular physiology 20070101 |
| Nicotinamide reverses neurological and neurovascular deficits in streptozotocin diabetic rats. | The Journal of pharmacology and experimental therapeutics 20070101 |
| Results from an in vitro and a clinical/pharmacological phase I study with the combination irinotecan and sorafenib. | European journal of cancer (Oxford, England : 1990) 20070101 |
| Altered gene expression in rat mesenteric tissue following in vivo exposure to a phosphodiesterase 4 inhibitor. | Toxicology and applied pharmacology 20070101 |
| NAD+ metabolism in health and disease. | Trends in biochemical sciences 20070101 |
| Keratoacanthomas associated with sorafenib therapy. | Journal of the American Academy of Dermatology 20070101 |
| Use of molecular imaging to quantify response to IKK-2 inhibitor treatment in murine arthritis. | Arthritis and rheumatism 20070101 |
| The ability of sorafenib to inhibit oncogenic PDGFRbeta and FLT3 mutants and overcome resistance to other small molecule inhibitors. | Haematologica 20070101 |
| [Therapy sequence for renal cell carcinoma--new aspects!]. | Aktuelle Urologie 20070101 |
| Sorafenib: in advanced renal cancer. | Drugs 20070101 |
| Newly approved therapies for RCC and their effect on the standard of care. | Clinical advances in hematology & oncology : H&O 20070101 |
| Rap1/B-Raf signaling is activated in neuroendocrine tumors of the digestive tract and Raf kinase inhibition constitutes a putative therapeutic target. | Neuroendocrinology 20070101 |
| Sunitinib malate and sorafenib may be beneficial at the treatment of advanced bladder cancer due to their anti-angiogenic effects. | Medical hypotheses 20070101 |
| [Relation between cytochrome P450 2D6 and lung cancer susceptibility caused by smoking]. | Wei sheng yan jiu = Journal of hygiene research 20070101 |
| Nongenetic model of type 2 diabetes: a comparative study. | Pharmacology 20070101 |
| Structure-activity relationship studies of arylthiazolidine amides as selective cytotoxic agents for melanoma. | Anticancer research 20070101 |
| Relationship between uremic toxins and oxidative stress in patients with chronic renal failure. | Scandinavian journal of urology and nephrology 20070101 |
| Celecoxib:nicotinamide dissociation: using excipients to capture the cocrystal's potential. | Molecular pharmaceutics 20070101 |
| Rationale and clinical results of multi-target treatments in oncology. | The International journal of biological markers 20070101 |
| Renal cell cancer and sorafenib: skin toxicity and treatment outcome. | Tumori 20070101 |
| Simultaneous determination of B-group vitamins in enriched Brazilian dairy products. | Critical reviews in food science and nutrition 20070101 |
| The role of targeted therapy in metastatic renal cell carcinoma. | TheScientificWorldJournal 20070101 |
| Combination therapy targeting the tumor microenvironment is effective in a model of human ocular melanoma. | Journal of translational medicine 20070101 |
| [Effect of angiogenesis inhibitors on renal cell carcinoma]. | Magyar onkologia 20070101 |
| [Vitamin intake in an average diet of Warsaw adult inhabitants]. | Roczniki Panstwowego Zakladu Higieny 20070101 |
| Targeted therapies for kidney cancer in urologic practice. | Urologic oncology 20070101 |
| Sorafenib: atypical cutaneous side effects. | European journal of dermatology : EJD 20070101 |
| Cocrystal architecture and properties: design and building of chiral and racemic structures by solid-solid reactions. | Faraday discussions 20070101 |
| [Angiogenesis targeting in renal carcinomas]. | Bulletin du cancer 20070101 |
| Synthesis and evaluation of the antiinflammatory activity of N-[2-(3,5-di-tert-butyl-4-hydroxyphenyl)-4-oxo-thiazolidin-3-yl]-nicotinamide. | Arzneimittel-Forschung 20070101 |
| PARP inhibitors accelerate N-methyl-N-nitrosourea-induced cataractogenesis in Sprague-Dawley rats. | In vivo (Athens, Greece) 20070101 |
| Changes in vitamin status of Indian Antarctic expeditioners during a one-month stay in Austral Summer. | Wilderness & environmental medicine 20070101 |
| [New treatments for renal carcinoma]. | Anales del sistema sanitario de Navarra 20070101 |
| Metabolites of the radiosensitizer nicotinamide are unlikely to contribute to the degree of emesis observed with the parent drug. | Oncology research 20070101 |
| [Noncoenzyme function of vitamin PP and its biologically active derivatives: the current state of the problem]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20070101 |
| Safety and activity of sorafenib in different histotypes of advanced renal cell carcinoma. | Oncology 20070101 |
| Effective palliation of advanced cholangiocarcinoma with sorafenib: a two-patient case report. | Journal of gastrointestinal cancer 20070101 |
| Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5. | Cancer research 20061215 |
| Targeting von Hippel-Lindau pathway in renal cell carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20061215 |
| Sorafenib for the treatment of advanced renal cell carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20061215 |
| The effects of nicotinamide on apoptosis and blood-brain barrier breakdown following traumatic brain injury. | Brain research 20061213 |
| Targeted therapy for metastatic renal cell carcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20061210 |
| Isocyanide addition to pyridinium salts. Efficient entry into substituted nicotinonitrile derivatives. | Organic letters 20061207 |
| Enantioselective synthesis of functionalized medium-sized oxacycles. | Organic letters 20061207 |
| The 2'-phosphate of NADP is responsible for proper orientation of the nicotinamide ring in the oxidative decarboxylation reaction catalyzed by sheep liver 6-phosphogluconate dehydrogenase. | The Journal of biological chemistry 20061201 |
| Coadministration of sorafenib with rottlerin potently inhibits cell proliferation and migration in human malignant glioma cells. | The Journal of pharmacology and experimental therapeutics 20061201 |
| YM-244769, a novel Na+/Ca2+ exchange inhibitor that preferentially inhibits NCX3, efficiently protects against hypoxia/reoxygenation-induced SH-SY5Y neuronal cell damage. | Molecular pharmacology 20061201 |
| Treatment of irritable bowel syndrome. A case control experience. | Minerva gastroenterologica e dietologica 20061201 |
| Sirtuin-independent effects of nicotinamide on lifespan extension from calorie restriction in yeast. | Aging cell 20061201 |
| New weapons to snuff out kidney cancer. | Nursing 20061201 |
| Neuroprotection in Parkinson models varies with toxin administration protocol. | The European journal of neuroscience 20061201 |
| Molecularly targeted therapy in renal cell carcinoma: where do we go from here? | Expert review of anticancer therapy 20061201 |
| Targeted therapies in metastatic renal cell carcinoma: the light at the end of the tunnel. | Expert review of anticancer therapy 20061201 |
| Tyrosine kinase inhibitors compared with cytokine therapy for metastatic renal cell carcinoma: overview of recent clinical trials differentiating clinical response and adverse effects. | Clinical genitourinary cancer 20061201 |
| Improving outcomes with novel therapies for patients with newly diagnosed renal cell carcinoma. | Clinical genitourinary cancer 20061201 |
| Toxicities of antiangiogenic therapy in non-small-cell lung cancer. | Clinical lung cancer 20061201 |
| Effects of histone deacetylase inhibitors, sodium phenyl butyrate and vitamin B3, in combination with retinoic acid on granulocytic differentiation of human promyelocytic leukemia HL-60 cells. | Annals of the New York Academy of Sciences 20061201 |
| Episodic vestibular disruption following ablation of the inferior olive in rats: behavioral correlates. | Behavioural brain research 20061125 |
| Raf kinases: oncogenesis and drug discovery. | International journal of cancer 20061115 |
| Nicotinamide reduces acute cortical neuronal death and edema in the traumatically injured brain. | Neuroscience letters 20061106 |
| [Symmetrical bullous acral erythema in a 58-year-old female alcoholic]. | Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20061101 |
| Inflammation of actinic keratoses subsequent to therapy with sorafenib, a multitargeted tyrosine-kinase inhibitor. | Clinical and experimental dermatology 20061101 |
| Plasticity of the central nervous system (CNS) following perinatal asphyxia: does nicotinamide provide neuroprotection? | Amino acids 20061101 |
| Preconditioning effects of peroxynitrite in the rat lung. | Pharmacological research 20061101 |
| Sorafenib. | Current opinion in oncology 20061101 |
| Nicotinamide (vitamin B3) increases the polyploidisation and proplatelet formation of cultured primary human megakaryocytes. | British journal of haematology 20061101 |
| Inhibition of tumor endothelial ERK activation, angiogenesis, and tumor growth by sorafenib (BAY43-9006). | The American journal of pathology 20061101 |
| The association of acetyl-l-carnitine and nicotinamide remits the experimental diabetes in mice by multiple low-dose streptozotocin. | Pancreas 20061101 |
| Protein kinases as drug targets in cancer. | Current cancer drug targets 20061101 |
| Leukocytoclastic vasculitis masquerading as hand-foot syndrome in a patient treated with sorafenib. | Archives of dermatology 20061101 |
| The antioxidant role of pterostilbene in streptozotocin-nicotinamide-induced type 2 diabetes mellitus in Wistar rats. | The Journal of pharmacy and pharmacology 20061101 |
| Second-line treatment of non-small cell lung cancer: big targets, small progress; small targets, big progress? | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20061101 |
| Beyond imatinib: second generation c-KIT inhibitors for the management of gastrointestinal stromal tumors. | Clinical colorectal cancer 20061101 |
| Simultaneous determination of riboflavin, pyridoxine, nicotinamide, caffeine and taurine in energy drinks by planar chromatography-multiple detection with confirmation by electrospray ionization mass spectrometry. | Journal of chromatography. A 20061027 |
| A novel nucleotide found in human erythrocytes, 4-pyridone-3-carboxamide-1-beta-D-ribonucleoside triphosphate. | The Journal of biological chemistry 20061027 |
| Isolation and characterization of dominant and recessive IL-3-independent hematopoietic transformants. | Oncogene 20061026 |
| Role of small bioorganic molecules in stem cell differentiation to insulin-producing cells. | Bioorganic & medicinal chemistry 20061001 |
| Antihyperglycemic effect of aporphines and their derivatives in normal and diabetic rats. | Planta medica 20061001 |
| Nicotinamide extends replicative lifespan of human cells. | Aging cell 20061001 |
| To predict progression-free survival and overall survival in metastatic renal cancer treated with sorafenib: pilot study using dynamic contrast-enhanced Doppler ultrasound. | European journal of cancer (Oxford, England : 1990) 20061001 |
| Randomized discontinuation trial of sorafenib (BAY 43-9006). | Cancer biology & therapy 20061001 |
| Reversible posterior leukoencephalopathy syndrome induced by RAF kinase inhibitor BAY 43-9006. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20061001 |
| Problems with the randomized discontinuation design. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20061001 |
| IKKbeta inhibition protects against bone and cartilage destruction in a rat model of rheumatoid arthritis. | Arthritis and rheumatism 20061001 |
| Discovery and development of sorafenib: a multikinase inhibitor for treating cancer. | Nature reviews. Drug discovery 20061001 |
| Nicotinamide treatment reduces behavioral impairments and provides cortical protection after fluid percussion injury in the rat. | Journal of neurotrauma 20061001 |
| [Managing the side effects of angiogenetic inhibitors in metastatic renal cell carcinoma]. | Der Urologe. Ausg. A 20061001 |
| Speeding up cancer-drug development. | The Lancet. Oncology 20061001 |
| Wells syndrome: an enigmatic and therapeutically challenging disease. | Journal of drugs in dermatology : JDD 20061001 |
| Zinc neurotoxicity is dependent on intracellular NAD levels and the sirtuin pathway. | The European journal of neuroscience 20061001 |
| Molecular biology of renal cell carcinoma. | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20061001 |
| A tale of two drugs. | Nature reviews. Drug discovery 20061001 |
| Antioxidant effect of tetrahydrocurcumin in streptozotocin-nicotinamide induced diabetic rats. | Life sciences 20060927 |
| Phase II study of sorafenib in patients with advanced hepatocellular carcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060910 |
| Sorafenib in advanced melanoma: a Phase II randomised discontinuation trial analysis. | British journal of cancer 20060904 |
| Fingerprinting DHFR in single-molecule AFM studies. | Biophysical journal 20060901 |
| Improved human islet isolation using nicotinamide. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060901 |
| New treatment approaches in metastatic renal cell carcinoma. | Current opinion in urology 20060901 |
| AMG 706, an oral, multikinase inhibitor that selectively targets vascular endothelial growth factor, platelet-derived growth factor, and kit receptors, potently inhibits angiogenesis and induces regression in tumor xenografts. | Cancer research 20060901 |
| Pharmacy benefit spending on oral chemotherapy drugs. | Journal of managed care pharmacy : JMCP 20060901 |
| Cytotoxic synergy between the multikinase inhibitor sorafenib and the proteasome inhibitor bortezomib in vitro: induction of apoptosis through Akt and c-Jun NH2-terminal kinase pathways. | Molecular cancer therapeutics 20060901 |
| Sorafenib (BAY 43-9006): review of clinical development. | Current clinical pharmacology 20060901 |
| Creation of a broad-range and highly stereoselective D-amino acid dehydrogenase for the one-step synthesis of D-amino acids. | Journal of the American Chemical Society 20060823 |
| Sorafenib is a potent inhibitor of FIP1L1-PDGFRalpha and the imatinib-resistant FIP1L1-PDGFRalpha T674I mutant. | Blood 20060815 |
| A new rapid and simple colorimetric method to detect pyrazinamide resistance in Mycobacterium tuberculosis using nicotinamide. | The Journal of antimicrobial chemotherapy 20060801 |
| Role of Raf kinase in cancer: therapeutic potential of targeting the Raf/MEK/ERK signal transduction pathway. | Seminars in oncology 20060801 |
| Sexual dimorphism in insulin sensitivity and susceptibility to develop diabetes in rats. | The Journal of endocrinology 20060801 |
| The effects of calcitriol and nicotinamide on residual pancreatic beta-cell function in patients with recent-onset Type 1 diabetes (IMDIAB XI). | Diabetic medicine : a journal of the British Diabetic Association 20060801 |
| Delayed treatment with nicotinamide inhibits brain energy depletion, improves cerebral microperfusion, reduces brain infarct volume, but does not alter neurobehavioral outcome following permanent focal cerebral ischemia in Sprague Dawley rats. | Current neurovascular research 20060801 |
| Effect of tetrahydrocurcumin on lipid peroxidation and lipids in streptozotocin-nicotinamide-induced diabetic rats. | Basic & clinical pharmacology & toxicology 20060801 |
| Current and future management of GIST. | Clinical advances in hematology & oncology : H&O 20060801 |
| Trials probe new agents for kidney cancer. | JAMA 20060712 |
| The sirtuins hst3 and Hst4p preserve genome integrity by controlling histone h3 lysine 56 deacetylation. | Current biology : CB 20060711 |
| Effect of pterostilbene on hepatic key enzymes of glucose metabolism in streptozotocin- and nicotinamide-induced diabetic rats. | Life sciences 20060710 |
| Acetylation of estrogen receptor alpha by p300 at lysines 266 and 268 enhances the deoxyribonucleic acid binding and transactivation activities of the receptor. | Molecular endocrinology (Baltimore, Md.) 20060701 |
| Novel synthesis of nicotinamide derivatives of cytotoxic properties. | Bioorganic & medicinal chemistry 20060701 |
| Activation of Sirt1 decreases adipocyte formation during osteoblast differentiation of mesenchymal stem cells. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20060701 |
| Spectrofluorimetric determination of drugs containing active methylene group using N1-methyl nicotinamide chloride as a fluorigenic agent. | Chemical & pharmaceutical bulletin 20060701 |
| Effects of hyperoxygenation on FDG-uptake in head-and-neck cancer. | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20060701 |
| The effect of a nicorandil congener on isolated human myometrium. | European journal of obstetrics, gynecology, and reproductive biology 20060601 |
| Nicotinamide extends the replicative life span of primary human cells. | Mechanisms of ageing and development 20060601 |
| Accumulation of poly(ADP-ribose) polymerase inhibitors in children with chronic renal failure. | Pediatric nephrology (Berlin, Germany) 20060601 |
| Phase II placebo-controlled randomized discontinuation trial of sorafenib in patients with metastatic renal cell carcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060601 |
| Effect of nicotinamide on newly diagnosed type 1 diabetic children. | Acta pharmacologica Sinica 20060601 |
| The prognostic value of endogenous hypoxia-related markers for head and neck squamous cell carcinomas treated with ARCON. | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20060601 |
| Establishment and pathophysiological characterization of type 2 diabetic mouse model produced by streptozotocin and nicotinamide. | Biological & pharmaceutical bulletin 20060601 |
| Targeting Raf-kinase: molecular rationales and translational issues. | Annals of oncology : official journal of the European Society for Medical Oncology 20060601 |
| Molecular targeting therapy for renal cell carcinoma. | International journal of clinical oncology 20060601 |
| Clinical activity of sorafenib and sunitinib in renal cell carcinoma refractory to previous vascular endothelial growth factor-targeted therapy: two case reports. | Clinical genitourinary cancer 20060601 |
| Effect of standard nicotinamide in the prevention of type 1 diabetes in first degree relatives of persons with type 1 diabetes. | Autoimmunity 20060601 |
| New therapeutic options for renal cell carcinoma. | Clinical advances in hematology & oncology : H&O 20060601 |
| Metabolite of SIR2 reaction modulates TRPM2 ion channel. | The Journal of biological chemistry 20060519 |
| The simultaneous measurement of nicotinamide adenine dinucleotide and related compounds by liquid chromatography/electrospray ionization tandem mass spectrometry. | Analytical biochemistry 20060515 |
| Carbogen and nicotinamide increase blood flow and 5-fluorouracil delivery but not 5-fluorouracil retention in colorectal cancer metastases in patients. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060515 |
| Lack of effect of ketoconazole-mediated CYP3A inhibition on sorafenib clinical pharmacokinetics. | Cancer chemotherapy and pharmacology 20060501 |
| Effect of a mixture of caffeine and nicotinamide on the solubility of vitamin (B2) in aqueous solution. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20060501 |
| Pharmacodynamic monitoring of BAY 43-9006 (Sorafenib) in phase I clinical trials involving solid tumor and AML/MDS patients, using flow cytometry to monitor activation of the ERK pathway in peripheral blood cells. | Cytometry. Part B, Clinical cytometry 20060501 |
| Results of a Phase I trial of sorafenib (BAY 43-9006) in combination with doxorubicin in patients with refractory solid tumors. | Annals of oncology : official journal of the European Society for Medical Oncology 20060501 |
| Tetraethylammonium and nicotine transport by the Malpighian tubules of insects. | Journal of insect physiology 20060501 |
| Catalase-peroxidase of Mycobacterium bovis BCG converts isoniazid to isonicotinamide, but not to isonicotinic acid: differentiation parameter between enzymes of Mycobacterium bovis BCG and Mycobacterium tuberculosis. | Biochimica et biophysica acta 20060501 |
| Ultrasound enhanced skin-lightening effect of vitamin C and niacinamide. | Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 20060501 |
| Diarrhea induced by high doses of nicotinamide in dialysis patients. | Kidney international 20060501 |
| Fetal alcohol syndrome and essential fatty acids. | PLoS medicine 20060501 |
| Emerging efficacy endpoints for targeted therapies in advanced renal cell carcinoma. | Oncology (Williston Park, N.Y.) 20060501 |
| Targeted therapy for cytokine-refractory metastatic renal cell carcinoma, and treatment in the community. | Oncology (Williston Park, N.Y.) 20060501 |
| Quantitation of nicotinamide and serotonin derivatives and detection of flavins in neuronal extracts using capillary electrophoresis with multiphoton-excited fluorescence. | Journal of chromatography. A 20060414 |
| Measurements of insulin responses as predictive markers of pancreatic beta-cell mass in normal and beta-cell-reduced lean and obese Göttingen minipigs in vivo. | American journal of physiology. Endocrinology and metabolism 20060401 |
| Nicotinamide protects against ethanol-induced apoptotic neurodegeneration in the developing mouse brain. | PLoS medicine 20060401 |
| Non-enzymatic regeneration of nicotinamide and flavin cofactors for monooxygenase catalysis. | Trends in biotechnology 20060401 |
| What's new in pancreatic cancer treatment pipeline? | Best practice & research. Clinical gastroenterology 20060401 |
| Protection against prenatal alcohol-induced damage. | PLoS medicine 20060401 |
| New tacrine-hydrazinonicotinamide hybrids as acetylcholinesterase inhibitors of potential interest for the early diagnostics of Alzheimer's disease. | Die Pharmazie 20060401 |
| Nicotinamide reduces high secretion of IFN-gamma in high-risk relatives even though it does not prevent type 1 diabetes. | Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20060401 |
| Comparison of metabolic fates of nicotinamide, NAD+ and NADH administered orally and intraperitoneally; characterization of oral NADH. | Journal of nutritional science and vitaminology 20060401 |
| Nicotinamide reduces hypoxic ischemic brain injury in the newborn rat. | Brain research bulletin 20060331 |
| Effects of ingested fruiting bodies, submerged culture biomass, and acidic polysaccharide glucuronoxylomannan of Tremella mesenterica Retz.:Fr. on glycemic responses in normal and diabetic rats. | Life sciences 20060320 |
| Mechanisms of hypertension associated with BAY 43-9006. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060320 |
| Targeted therapy for metastatic renal cell carcinoma. | British journal of cancer 20060313 |
| Nicotinamide blocks N-methyl-N-nitrosourea-induced photoreceptor cell apoptosis in rats through poly (ADP-ribose) polymerase activity and Jun N-terminal kinase/activator protein-1 pathway inhibition. | Experimental eye research 20060301 |
| Nicotinamide protected first-phase insulin response (FPIR) and prevented clinical disease in first-degree relatives of type-1 diabetics. | Diabetes research and clinical practice 20060301 |
| Pooled safety analysis of BAY 43-9006 (sorafenib) monotherapy in patients with advanced solid tumours: Is rash associated with treatment outcome? | European journal of cancer (Oxford, England : 1990) 20060301 |
| A multiphase microscopic diffusion model for stratum corneum permeability. I. Formulation, solution, and illustrative results for representative compounds. | Journal of pharmaceutical sciences 20060301 |
| Modified two-layer preservation method (M-Kyoto/PFC) improves islet yields in islet isolation. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060301 |
| Sorafenib. | Expert opinion on pharmacotherapy 20060301 |
| MafA expression and insulin promoter activity are induced by nicotinamide and related compounds in INS-1 pancreatic beta-cells. | Diabetes 20060301 |
| VEGF-targeted therapy in renal cell carcinoma: active drugs and active choices. | Current oncology reports 20060301 |
| BAY 43-9006 inhibition of oncogenic RET mutants. | Journal of the National Cancer Institute 20060301 |
| BRAF is a therapeutic target in aggressive thyroid carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060301 |
| Multi-target inhibitors in non-small cell lung cancer (NSCLC). | Annals of oncology : official journal of the European Society for Medical Oncology 20060301 |
| Molecule of the month. Sorafenib. | Drug news & perspectives 20060301 |
| Sorafenib: recent update on activity as a single agent and in combination with interferon-alpha2 in patients with advanced-stage renal cell carcinoma. | Clinical genitourinary cancer 20060301 |
| [Bullous pemphigoid: diagnostics and new therapeutic strategies]. | Deutsche medizinische Wochenschrift (1946) 20060224 |
| Leishmania major and Leishmania tropica: II. Effect of an immunomodulator, S(2) complex on the enzymes of the parasites. | Experimental parasitology 20060201 |
| Estimation of aldehyde oxidase activity in vivo from conversion ratio of N1-methylnicotinamide to pyridones, and intraspecies variation of the enzyme activity in rats. | Drug metabolism and disposition: the biological fate of chemicals 20060201 |
| The Raf inhibitor BAY 43-9006 (Sorafenib) induces caspase-independent apoptosis in melanoma cells. | Cancer research 20060201 |
| [Progress in therapeutic strategy for renal cell carcinoma]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060201 |
| Drug approval triggers debate on future direction for cancer treatments. | Nature reviews. Drug discovery 20060201 |
| [Hartnup disorder: Pathogenesis, pathophysiology, and therapy]. | Nihon rinsho. Japanese journal of clinical medicine 20060201 |
| Raf-1 kinase associates with Hepatitis C virus NS5A and regulates viral replication. | FEBS letters 20060123 |
| Spatial variation in the degradation rate of the pesticides isoproturon, azoxystrobin and diflufenican in soil and its relationship with chemical and microbial properties. | Environmental pollution (Barking, Essex : 1987) 20060101 |
| Oxygen-modifying treatment with ARCON reduces the prognostic significance of hemoglobin in squamous cell carcinoma of the head and neck. | International journal of radiation oncology, biology, physics 20060101 |
| Hypoxia stimulates Ca2+ release from intracellular stores in astrocytes via cyclic ADP ribose-mediated activation of ryanodine receptors. | Cell calcium 20060101 |
| Phase I trial of sorafenib and gemcitabine in advanced solid tumors with an expanded cohort in advanced pancreatic cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060101 |
| Nicotinamide increases thyroid radiosensitivity by stimulating nitric oxide synthase expression and the generation of organic peroxides. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20060101 |
| Treatment of pemphigus vulgaris. An overview in Mexico. | Allergologia et immunopathologia 20060101 |
| New drugs: abatacept, sorafenib, and nelarabine. | Journal of the American Pharmacists Association : JAPhA 20060101 |
| Impact of the two-layer method on the quality of isolated pancreatic islets. | Hepato-gastroenterology 20060101 |
| Cell Life versus cell longevity: the mysteries surrounding the NAD+ precursor nicotinamide. | Current medicinal chemistry 20060101 |
| [Interaction between aromatic antibiotics and vitamins: 1H NMR analysis of the heteroassociation of nicotinamide and anthracycline antitumor antibiotics]. | Biofizika 20060101 |
| Treatment for advanced kidney cancer. | FDA consumer 20060101 |
| Search for drugs of the combined anti-inflammatory and anti-bacterial properties: 1-methyl-N'-(hydroxymethyl)nicotinamide. | Pharmacological reports : PR 20060101 |
| Tryptophan-niacin metabolism in rat with puromycin aminonucleoside-induced nephrosis. | International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20060101 |
| Reaction crystallization of pharmaceutical molecular complexes. | Molecular pharmaceutics 20060101 |
| Sorafenib (BAY 43-9006, Nexavar), a dual-action inhibitor that targets RAF/MEK/ERK pathway in tumor cells and tyrosine kinases VEGFR/PDGFR in tumor vasculature. | Methods in enzymology 20060101 |
| [The effect of magnesium pool isotopy on reactivation of mitochondrial ATP synthesis suppressed by 1-methyl-nicotine amide]. | Biomeditsinskaia khimiia 20060101 |
| [Modulation of reactivity of cyclic adenosine monophosphate phosphodiesterase under the effect of pyridinecarboxylic acid derivatives and Pt(IV) metal complexes on their basis]. | Biomeditsinskaia khimiia 20060101 |
| The mechanisms of action of nicotinamide and zinc in inflammatory skin disease. | Cutis 20060101 |
| Pharmacologic doses of nicotinamide in the treatment of inflammatory skin conditions: a review. | Cutis 20060101 |
| The Nicomide Improvement in Clinical Outcomes Study (NICOS): results of an 8-week trial. | Cutis 20060101 |
| [Heteroassociation of antibiotic norfloxacin with aromatic vitamins in aqueous solution]. | Biofizika 20060101 |
| Succinic acid monoethyl ester prevents oxidative stress in streptozotocin-nicotinamide-induced type2 diabetic rats. | Journal of basic and clinical physiology and pharmacology 20060101 |
| Renal cell carcinoma: today's targeted therapies improving tomorrow's outcomes. | ONS news 20060101 |
| Multitargeted agents for therapeutically challenging tumor: an introduction for oncology nurses. | ONS news 20060101 |
| The novel nucleotide 4KNTP, in high concentrations in erythrocytes of renal failure children: a comparison with accumulation of other putative precursors in the plasma. | Nucleosides, nucleotides & nucleic acids 20060101 |
| Liquid chromatographic/mass spectrometric procedure for measurement of NAD catabolites in human and rat plasma and urine. | Nucleosides, nucleotides & nucleic acids 20060101 |
| Anti-hyperglycemic activity of natural and fermented Cordyceps sinensis in rats with diabetes induced by nicotinamide and streptozotocin. | The American journal of Chinese medicine 20060101 |
| Inhibition of poly (ADP-ribose) polymerase as a protective effect of nicaraven in ionizing radiation- and ara-C-induced cell death. | Anticancer research 20060101 |
| [Mechanisms of diabetes-induced impairements of serotonin release from rat brain synaptosomes: effect of nicotinamide]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20060101 |
| Effect of tetrahydrocurcumin on plasma antioxidants in streptozotocin-nicotinamide experimental diabetes. | Journal of basic and clinical physiology and pharmacology 20060101 |
| Report of the 2006 APhA House of Delegates. | Journal of the American Pharmacists Association : JAPhA 20060101 |
| Medical treatment of gastrointestinal stromal tumors: state of the art and future perspectives. | Reviews on recent clinical trials 20060101 |
| Simultaneous determination of myristyl nicotinate, nicotinic acid, and nicotinamide in rabbit plasma by liquid chromatography-tandem mass spectrometry using methyl ethyl ketone as a deproteinization solvent. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20051227 |
| Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1. | Journal of medicinal chemistry 20051215 |
| Thrombocytopenia induced by nicotinamide in hemodialysis patients. | Kidney international 20051201 |
| Sorafenib: scientific rationales for single-agent and combination therapy in clear-cell renal cell carcinoma. | Clinical genitourinary cancer 20051201 |
| Preclinical and clinical development of the oral multikinase inhibitor sorafenib in cancer treatment. | Drugs of today (Barcelona, Spain : 1998) 20051201 |
| Effects of excess pantothenic acid administration on the other water-soluble vitamin metabolisms in rats. | Journal of nutritional science and vitaminology 20051201 |
| [Treatment of hyperphosphatemia in hemodialysis patients]. | Nephrologie & therapeutique 20051201 |
| Nicotinamide promotes long-term survival and extensive neurite outgrowth in ultimobranchial C cells cultured from chick embryos. | The Journal of comparative neurology 20051121 |
| Ligand binding modulates the mechanical stability of dihydrofolate reductase. | Biophysical journal 20051101 |
| Nicotinamide: a double edged sword. | Parkinsonism & related disorders 20051101 |
| Topical application of 1-methylnicotinamide in the treatment of rosacea: a pilot study. | Clinical and experimental dermatology 20051101 |
| Update on angiogenesis inhibitors. | Current opinion in oncology 20051101 |
| Increased life span due to calorie restriction in respiratory-deficient yeast. | PLoS genetics 20051101 |
| [Fast separation of nicotinamide and nicotinic acid with molecularly imprinted monolithic column]. | Se pu = Chinese journal of chromatography 20051101 |
| Apoptosis induced by the kinase inhibitor BAY 43-9006 in human leukemia cells involves down-regulation of Mcl-1 through inhibition of translation. | The Journal of biological chemistry 20051021 |
| The role of Mcl-1 downregulation in the proapoptotic activity of the multikinase inhibitor BAY 43-9006. | Oncogene 20051020 |
| Phase I study to determine the safety and pharmacokinetics of the novel Raf kinase and VEGFR inhibitor BAY 43-9006, administered for 28 days on/7 days off in patients with advanced, refractory solid tumors. | Annals of oncology : official journal of the European Society for Medical Oncology 20051001 |
| Identification of ortho-amino benzamides and nicotinamides as MCHr1 antagonists. | Bioorganic & medicinal chemistry letters 20051001 |
| Vitamin B3 confers resistance to sulfa drugs in Saccharomyces cerevisiae. | FEMS microbiology letters 20051001 |
| Nicotinamide induces apoptosis and reduces collagen I and pro-inflammatory cytokines expression in rat hepatic stellate cells. | Scandinavian journal of gastroenterology 20051001 |
| The sirtuin inhibitor nicotinamide enhances neuronal cell survival during acute anoxic injury through AKT, BAD, PARP, and mitochondrial associated 'anti-apoptotic' pathways. | Current neurovascular research 20051001 |
| Diverse effects of calcium channel blockers in the collar model. | Acta cardiologica 20051001 |
| Values of water-soluble vitamins in blood and urine of Japanese young men and women consuming a semi-purified diet based on the Japanese Dietary Reference Intakes. | Journal of nutritional science and vitaminology 20051001 |
| Evidence for a role of energy dysregulation in the MDMA-induced depletion of brain 5-HT. | Brain research 20050921 |
| Raf: a strategic target for therapeutic development against cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050920 |
| Nicotinamide in relation to dietary nicotinic acid and nine other vitamins and larval development of Ceratitis capitata (Diptera: Tephritidae). | Journal of agricultural and food chemistry 20050907 |
| Toward a unified theory of caloric restriction and longevity regulation. | Mechanisms of ageing and development 20050901 |
| Leishmania major and Leishmania tropica: I the in vitro effects of an immunomodulator, S2-Complex. | Experimental parasitology 20050901 |
| Vitamin B3 and sirtuin function. | Trends in biochemical sciences 20050901 |
| Promising systemic therapy for renal cell carcinoma. | Current treatment options in oncology 20050901 |
| Differentiation of human liver-derived, insulin-producing cells toward the beta-cell phenotype. | Diabetes 20050901 |
| Modulation of hypoxia in murine liver metastases of colon carcinoma by nicotinamide and carbogen. | Radiation research 20050901 |
| Targeting angiogenesis with vascular endothelial growth factor receptor small-molecule inhibitors: novel agents with potential in lung cancer. | Clinical lung cancer 20050901 |
| Spinal cord metastasis of a non-neurofibromatosis type-1 malignant peripheral nerve sheath tumor: an unusual manifestation of a rare tumor. | Journal of neuro-oncology 20050901 |
| Results of a phase I trial of sorafenib (BAY 43-9006) in combination with oxaliplatin in patients with refractory solid tumors, including colorectal cancer. | Clinical colorectal cancer 20050901 |
| Location of the coenzyme binding site in the porcine mitochondrial NADP-dependent isocitrate dehydrogenase. | The Journal of biological chemistry 20050826 |
| Subungual splinter hemorrhages: a clinical window to inhibition of vascular endothelial growth factor receptors? | Annals of internal medicine 20050816 |
| Rainfastness and adsorption of herbicides on hard surfaces. | Pest management science 20050801 |
| Recent progress in targeting the Raf/MEK/ERK pathway with inhibitors in cancer drug discovery. | Current opinion in pharmacology 20050801 |
| Water-soluble vitamins: research update. | Current sports medicine reports 20050801 |
| Therapy targeted at vascular endothelial growth factor in metastatic renal cell carcinoma: biology, clinical results and future development. | BJU international 20050801 |
| Safety and pharmacokinetics of the dual action Raf kinase and vascular endothelial growth factor receptor inhibitor, BAY 43-9006, in patients with advanced, refractory solid tumors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050801 |
| Microplate filtration assay for nicotinamide release from NAD using a boronic acid resin. | Methods (San Diego, Calif.) 20050801 |
| Inhibition of radiation induced nitration by curcumin and nicotinamide in mouse macrophages. | Molecular and cellular biochemistry 20050801 |
| Adsorption isotherms on nicotinamide-imprinted polymer stationary phase. | Journal of chromatographic science 20050801 |
| Nicotinamide modulates energy utilization and improves functional recovery from ischemia in the in vitro rabbit retina. | Annals of the New York Academy of Sciences 20050801 |
| A two year observational study of nicotinamide and intensive insulin therapy in patients with recent onset type 1 diabetes mellitus. | Journal of pediatric endocrinology & metabolism : JPEM 20050801 |
| Niacinamide-containing facial moisturizer improves skin barrier and benefits subjects with rosacea. | Cutis 20050801 |
| Interventions for bullous pemphigoid. | The Cochrane database of systematic reviews 20050720 |
| Crystal structure of human dihydrolipoamide dehydrogenase: NAD+/NADH binding and the structural basis of disease-causing mutations. | Journal of molecular biology 20050715 |
| Nicotinamide prevents the development of hyperphosphataemia by suppressing intestinal sodium-dependent phosphate transporter in rats with adenine-induced renal failure. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20050701 |
| Structural transformations in the dynamics of Michaelis complex formation in lactate dehydrogenase. | Biophysical journal 20050701 |
| A forkhead in the road to longevity: the molecular basis of lifespan becomes clearer. | Journal of hypertension 20050701 |
| Cutaneous side-effects of kinase inhibitors and blocking antibodies. | The Lancet. Oncology 20050701 |
| Proteomic identification of differentially expressed proteins in the aging murine olfactory system and transcriptional analysis of the associated genes. | Journal of neurochemistry 20050701 |
| Effect of arylformamidase (kynurenine formamidase) gene inactivation in mice on enzymatic activity, kynurenine pathway metabolites and phenotype. | Biochimica et biophysica acta 20050620 |
| Discovery of an N-(2-aminopyridin-4-ylmethyl)nicotinamide derivative: a potent and orally bioavailable NCX inhibitor. | Bioorganic & medicinal chemistry 20050602 |
| Effect of glucagon-like peptide-1(7-36) and exendin-4 on the vascular reactivity in streptozotocin/nicotinamide-induced diabetic rats. | Pharmacology 20050601 |
| Acute and late morbidity in the treatment of advanced bladder carcinoma with accelerated radiotherapy, carbogen, and nicotinamide. | Cancer 20050601 |
| Increased tubular organic ion clearance following chronic ACE inhibition in patients with type 1 diabetes. | Kidney international 20050601 |
| Simultaneous determination of vitamins C, B6 and PP in pharmaceutics using differential pulse voltammetry with a glassy carbon electrode and multivariate calibration tools. | Journal of pharmaceutical and biomedical analysis 20050601 |
| Multi-kinase inhibitors create buzz at ASCO. | Nature biotechnology 20050601 |
| [Characteristics of N-methyl-N-nitrosourea-induced retinal degeneration in animals and application for the therapy of human retinitis pigmentosa]. | Nippon Ganka Gakkai zasshi 20050601 |
| Cancer. Encouraging results for second-generation antiangiogenesis drugs. | Science (New York, N.Y.) 20050527 |
| Phase I safety and pharmacokinetics of BAY 43-9006 administered for 21 days on/7 days off in patients with advanced, refractory solid tumours. | British journal of cancer 20050523 |
| Angiogenesis and lung cancer: prognostic and therapeutic implications. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050510 |
| Nicotinic acid limitation regulates silencing of Candida adhesins during UTI. | Science (New York, N.Y.) 20050506 |
| Clinical trials referral resource. | Oncology (Williston Park, N.Y.) 20050501 |
| Dissolution, solubility, XRD, and DSC studies on flurbiprofen-nicotinamide solid dispersions. | Drug development and industrial pharmacy 20050501 |
| Substrate-specific activation of sirtuins by resveratrol. | The Journal of biological chemistry 20050429 |
| SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}. | The Journal of biological chemistry 20050422 |
| Thermodynamics of alpha-lactalbumin-DL-alpha-dipalmitoylphosphatidylcholine interactions and effect of the antioxidant nicotinamide on these interactions. | Biophysical chemistry 20050422 |
| Activin A maintains pluripotency of human embryonic stem cells in the absence of feeder layers. | Stem cells (Dayton, Ohio) 20050401 |
| Supramolecular structures of three isomeric 2-chloro-N-(nitrophenyl)nicotinamides. | Acta crystallographica. Section C, Crystal structure communications 20050401 |
| Raf kinase as a target for anticancer therapeutics. | Molecular cancer therapeutics 20050401 |
| Formulation and in vitro/in vivo evaluation of combining DNA repair and immune enhancing nutritional supplements. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20050401 |
| Clinical trials referral resource. Current clinical trials of BAY 43-9006, Part 1. | Oncology (Williston Park, N.Y.) 20050401 |
| Neuroprotective effect of cytoflavin during compression injury of the spinal cord. | Bulletin of experimental biology and medicine 20050401 |
| Quantitation of the niacin metabolites 1-methylnicotinamide and l-methyl-2-pyridone-5-carboxamide in random spot urine samples, by ion-pairing reverse-phase HPLC with UV detection, and the implications for the use of spot urine samples in the assessment of niacin status. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050325 |
| Magnetic field effects on bioelectrocatalytic reactions of surface-confined enzyme systems: enhanced performance of biofuel cells. | Journal of the American Chemical Society 20050323 |
| Mechanism of sirtuin inhibition by nicotinamide: altering the NAD(+) cosubstrate specificity of a Sir2 enzyme. | Molecular cell 20050318 |
| Mutant V599EB-Raf regulates growth and vascular development of malignant melanoma tumors. | Cancer research 20050315 |
| The role of poly (adenosine 5'-diphosphate-ribose) polymerase in the response of pituitary tumor cells to reactive oxygen species. | Endocrinology 20050301 |
| Novel kinase inhibitors in renal cell carcinoma: progressive development of static agents. | Current oncology reports 20050301 |
| Parkinson's disease: the first common neurological disease due to auto-intoxication? | QJM : monthly journal of the Association of Physicians 20050301 |
| Endothelin-1, superoxide and adeninediphosphate ribose cyclase in shark vascular smooth muscle. | The Journal of experimental biology 20050301 |
| Moisturizing effects of topical nicotinamide on atopic dry skin. | International journal of dermatology 20050301 |
| Chemical activation of Sir2-dependent silencing by relief of nicotinamide inhibition. | Molecular cell 20050218 |
| The amide rotational barrier in isonicotinamide: Dynamic NMR and ab initio studies. | The journal of physical chemistry. A 20050217 |
| BCL11A-dependent recruitment of SIRT1 to a promoter template in mammalian cells results in histone deacetylation and transcriptional repression. | Archives of biochemistry and biophysics 20050215 |
| Mechanistic aspects of the deoxyribonuclease activity of diphtheria toxin. | Biochimica et biophysica acta 20050214 |
| Phase I clinical and pharmacokinetic study of the Novel Raf kinase and vascular endothelial growth factor receptor inhibitor BAY 43-9006 in patients with advanced refractory solid tumors. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050210 |
| Beta-cell function and islet morphology in normal, obese, and obese beta-cell mass-reduced Göttingen minipigs. | American journal of physiology. Endocrinology and metabolism 20050201 |
| Electron transfer kinetics and mechanistic study of the thionicotinamide coordinated to the pentacyanoferrate(III)/(II) complexes: a model system for the in vitro activation of thioamides anti-tuberculosis drugs. | Journal of inorganic biochemistry 20050201 |
| Synthesis and structure-activity relationships of 6-{4-[(3-fluorobenzyl)oxy]phenoxy}nicotinamide derivatives as a novel class of NCX inhibitors: a QSAR study. | Bioorganic & medicinal chemistry 20050201 |
| The Raf kinase inhibitor BAY 43-9006 reduces cellular uptake of platinum compounds and cytotoxicity in human colorectal carcinoma cell lines. | Anti-cancer drugs 20050201 |
| Raf kinase inhibitors in oncology. | Onkologie 20050201 |
| Diminished Th1-like response to autoantigens in children with a high risk of developing type 1 diabetes. | Scandinavian journal of immunology 20050201 |
| [The intervention of nicotinamide on skin melanocyte's cell proliferation after UVA (365 nm) exposed.]. | Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20050201 |
| NAD deamidation 'a new reaction' by an enzyme from Aspergillus terreus DSM 826. | Antonie van Leeuwenhoek 20050201 |
| [European Nicotinamide Diabetes Intervention Trial (ENDIT)--secondary publication. A randomized, placebo-controlled trial of intervention before the onset of type 1 diabetes]. | Ugeskrift for laeger 20050117 |
| Molecular switch based on a biologically important redox reaction. | The journal of physical chemistry. B 20050113 |
| Simultaneous determination of niacin, niacinamide and nicotinuric acid in human plasma. | Journal of pharmaceutical and biomedical analysis 20050104 |
| The novel phosphodiesterase 4 inhibitor, CI-1044, inhibits LPS-induced TNF-alpha production in whole blood from COPD patients. | Pulmonary pharmacology & therapeutics 20050101 |
| Autotoxicity, methylation and a road to the prevention of Parkinson's disease. | Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20050101 |
| Evaluation of protective ointments used against dermal effects of nitrogen mustard, a vesicant warfare agent. | Military medicine 20050101 |
| Study of interaction between ibuprofen and nicotinamide using differential scanning calorimetry, spectroscopy, and microscopy and formulation of a fast-acting and possibly better ibuprofen suspension for osteoarthritis patients. | Journal of pharmaceutical sciences 20050101 |
| Nicotinamide trials in diabetes intervention. Does a metabolite provide benefit? | Medical hypotheses 20050101 |
| Spectrofluorimetric determination of warfarin sodium by using N1-methylnicotinamide chloride as a fluorigenic agent. | Journal of AOAC International 20050101 |
| Nicotinamide homeostasis: a xenobiotic pathway that is key to development and degenerative diseases. | Medical hypotheses 20050101 |
| The effect of N-methyl-2-pyridone-5-carboxamide--A nicotinamide catabolite on poly ADP-rybosylation and oxidative stress injury in endothelial cells. | Nucleosides, nucleotides & nucleic acids 20050101 |
| N,N-bis(2-mercaptoethyl)methylamine: a new coligand for Tc-99m labeling of hydrazinonicotinamide peptides. | Bioconjugate chemistry 20050101 |
| [New therapy strategies in secondary hyperparathyroidism on dialysis (I): new concepts, new treatments]. | Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20050101 |
| Hyperthermic enhancement of tumor radiosensitization strategies. | Immunological investigations 20050101 |
| Oral doxycycline, niacinamide and prednisolone used to treat bilateral nodular granulomatous conjunctivitis of the third eyelid in an Australian Kelpie dog. | Veterinary ophthalmology 20050101 |
| Cell culture modeling to test therapies against hyperglycemia-mediated oxidative stress and injury. | Antioxidants & redox signaling 20050101 |
| [The impaired immune system and ways of its correction in critically ill patients with acute severe intoxication by neutropic poisons]. | Anesteziologiia i reanimatologiia 20050101 |
| [Treatment of hyperphosphatemia in dialyzed patients with nicotinamide]. | Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20050101 |
| [Effect of nicotinamide on the reactions of peroxide oxidation of biomolecules in the rat brain and erythrocytes in 1,2-dichloroethane toxic injury]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20050101 |
| Final report of the safety assessment of niacinamide and niacin. | International journal of toxicology 20050101 |
| Cancer targets in the Ras pathway. | Cold Spring Harbor symposia on quantitative biology 20050101 |
| Vapochromism and its structural basis in a luminescent Pt(II) terpyridine-nicotinamide complex. | Journal of the American Chemical Society 20041229 |
| Spotlight turns on cosmetics for Asian skin. | Nature 20041223 |
| Nicotinamide attenuates focal ischemic brain injury: meta-analysis or mechanism of protection. | Stroke 20041201 |
| Effects of hypervitaminosis of vitamin B3 on silkworm biology. | Journal of biosciences 20041201 |
| In vivo modulation of signaling factors involved in cell survival. | Journal of radiation research 20041201 |
| The age-related increase in N-methyl-2-pyridone-5-carboxamide (NAD catabolite) in human plasma. | Molecular and cellular biochemistry 20041201 |
| Conversion ratio of tryptophan to niacin in Japanese women fed a purified diet conforming to the Japanese Dietary Reference Intakes. | Journal of nutritional science and vitaminology 20041201 |
| Changes in the urinary excretion of the metabolites of the tryptophan-niacin pathway during pregnancy in Japanese women and rats. | Journal of nutritional science and vitaminology 20041201 |
| Nonpolymeric hydrogelator derived from N-(4-pyridyl)isonicotinamide. | Langmuir : the ACS journal of surfaces and colloids 20041123 |
| Silent information regulator 2alpha, a longevity factor and class III histone deacetylase, is an essential endogenous apoptosis inhibitor in cardiac myocytes. | Circulation research 20041112 |
| Cholecystokinin octapeptide: a potential growth factor for pancreatic beta cells in diabetic rats. | JOP : Journal of the pancreas 20041110 |
| The role of advanced glycation in reduced organic cation transport associated with experimental diabetes. | The Journal of pharmacology and experimental therapeutics 20041101 |
| In vivo determination of tumor oxygenation during growth and in response to carbogen breathing using 15C5-loaded alginate capsules as fluorine-19 magnetic resonance imaging oxygen sensors. | International journal of radiation oncology, biology, physics 20041101 |
| How thyroid tumors start and why it matters: kinase mutants as targets for solid cancer pharmacotherapy. | The Journal of endocrinology 20041101 |
| Inhibition of pea ferredoxin-NADP(H) reductase by Zn-ferrocyanide. | European journal of biochemistry 20041101 |
| Reduction of beta cell mass: partial insulin secretory compensation from the residual beta cell population in the nicotinamide-streptozotocin Göttingen minipig after oral glucose in vivo and in the perfused pancreas. | Diabetologia 20041101 |
| Correlation of ERK-phosphorylation and toxicities in patients treated with the Raf kinase inhibitor BAY 43-9006. | International journal of clinical pharmacology and therapeutics 20041101 |
| Results of a phase I trial of BAY 43-9006 in combination with doxorubicin in patients with primary hepatic cancer. | International journal of clinical pharmacology and therapeutics 20041101 |
| DNA cleavage induced by thermal electron transfer from a dimeric NADH analogue to acridinium ions in the presence of oxygen. | Journal of the American Chemical Society 20041013 |
| Glucosamine-induced alterations of mitochondrial function in pancreatic beta-cells: possible role of protein glycosylation. | American journal of physiology. Endocrinology and metabolism 20041001 |
| Redox-mediated enrichment of self-renewing adult human pancreatic cells that possess endocrine differentiation potential. | Pancreas 20041001 |
| BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. | Cancer research 20041001 |
| High interstitial fluid pressure - an obstacle in cancer therapy. | Nature reviews. Cancer 20041001 |
| An unusual pyridine nucleotide accumulating in erythrocytes: its identity and positive correlation with degree of renal failure. | Nucleosides, nucleotides & nucleic acids 20041001 |
| [Action site of bisphenol A as metabolic disruptor lies in the tryptophan-nicotinamide conversion pathway]. | Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20041001 |
| Novel agents for the treatment of advanced kidney cancer. | Clinical advances in hematology & oncology : H&O 20041001 |
| Validation of a liquid chromatography assay for the quantification of the Raf kinase inhibitor BAY 43-9006 in small volumes of mouse serum. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040925 |
| Stereoselective synthesis of nicotinamide beta-riboside and nucleoside analogs. | Bioorganic & medicinal chemistry letters 20040920 |
| Comparison of pathways controlling toxicity in the eye and brain in Drosophila models of human neurodegenerative diseases. | Human molecular genetics 20040915 |
| Kinase inhibition with BAY 43-9006 in renal cell carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040915 |
| Crystal structure of E.coli alcohol dehydrogenase YqhD: evidence of a covalently modified NADP coenzyme. | Journal of molecular biology 20040910 |
| Insulinotropic agent ID-1101 (4-hydroxyisoleucine) activates insulin signaling in rat. | American journal of physiology. Endocrinology and metabolism 20040901 |
| Fluorescence assay of SIRT protein deacetylases using an acetylated peptide substrate and a secondary trypsin reaction. | Analytical biochemistry 20040901 |
| Niacin metabolite excretion in alcoholic pellagra and AIDS patients with and without diarrhea. | Nutrition (Burbank, Los Angeles County, Calif.) 20040901 |
| Effects of nicotinamide and carbogen in different murine colon carcinomas: immunohistochemical analysis of vascular architecture and microenvironmental parameters. | International journal of radiation oncology, biology, physics 20040901 |
| Navigating novel mechanisms of cellular plasticity with the NAD+ precursor and nutrient nicotinamide. | Frontiers in bioscience : a journal and virtual library 20040901 |
| Micronutrients and the risk of type 1 diabetes: vitamin D, vitamin E, and nicotinamide. | Nutrition reviews 20040901 |
| B-RAF is a therapeutic target in melanoma. | Oncogene 20040819 |
| Physiological noise in murine solid tumours using T2*-weighted gradient-echo imaging: a marker of tumour acute hypoxia? | Physics in medicine and biology 20040807 |
| Kinetic and structural analysis of the increased affinity of enoyl-ACP (acyl-carrier protein) reductase for triclosan in the presence of NAD+. | The Biochemical journal 20040801 |
| Modulation of matrix metalloproteinase production from human lung fibroblasts by type 4 phosphodiesterase inhibitors. | Life sciences 20040702 |
| Channelling of substrate promiscuity of the skeletal-muscle ADP-ribosyl cyclase isoform. | The Biochemical journal 20040701 |
| Radiotoxicity on bone marrow after 89Sr therapy radiosensitized by nicotinamide and carbogen in mice. | Nuclear medicine communications 20040701 |
| The NAD+ precursor nicotinamide governs neuronal survival during oxidative stress through protein kinase B coupled to FOXO3a and mitochondrial membrane potential. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20040701 |
| Is sensitization with nicotinamide and carbogen dependent on nicotinamide concentration at the time of irradiation? | International journal of radiation biology 20040701 |
| Urea transport in MDCK cells that are stably transfected with UT-A1. | American journal of physiology. Cell physiology 20040601 |
| Inhibition of caspase-mediated PARP-1 cleavage results in increased necrosis in isolated islets of Langerhans. | Journal of molecular medicine (Berlin, Germany) 20040601 |
| Nicotinamide as a potential addition to the anti-atopic dermatitis armamentarium. | International immunopharmacology 20040601 |
| Selectivity of effects of redox-active cobalt(III) complexes on tumor tissue. | Experimental oncology 20040601 |
| Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans. | Cell 20040514 |
| Inhibition of human P450 enzymes by nicotinic acid and nicotinamide. | Biochemical and biophysical research communications 20040507 |
| Pooling of animal experimental data reveals influence of study design and publication bias. | Stroke 20040501 |
| A study on the interaction between 1-decyloxymethyl-3-carbamoylpyridinium salts and model membranes--the effect of counterions. | Biophysical chemistry 20040501 |
| A randomized trial of nicotinamide and vitamin E in children with recent onset type 1 diabetes (IMDIAB IX). | European journal of endocrinology 20040501 |
| Early administration of nicotinamide prevents learning and memory impairment in mice induced by 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine. | Pharmacology, biochemistry, and behavior 20040501 |
| The anti-hyperglycemic activity of the fruiting body of Cordyceps in diabetic rats induced by nicotinamide and streptozotocin. | Life sciences 20040423 |
| Kinetic mechanism of quinone oxidoreductase 2 and its inhibition by the antimalarial quinolines. | Biochemistry 20040420 |
| Cofactor hydrogen bonding onto the protein main chain is conserved in the short chain dehydrogenase/reductase family and contributes to nicotinamide orientation. | The Journal of biological chemistry 20040416 |
| Pemphigus: current therapy. | Veterinary dermatology 20040401 |
| The ApoCorrect assay: a novel, rapid method to determine the biological functionality of radiolabeled and fluorescent Annexin A5. | Analytical biochemistry 20040401 |
| Effects of cytoflavin and neuronol on morphological changes in the brain and survival of rats with ischemic disturbances in cerebral blood flow. | Bulletin of experimental biology and medicine 20040401 |
| Growing pains in the pursuit of diabetes prevention. | Lancet (London, England) 20040320 |
| European Nicotinamide Diabetes Intervention Trial (ENDIT): a randomised controlled trial of intervention before the onset of type 1 diabetes. | Lancet (London, England) 20040320 |
| Going Ku Ku on Bax. | Science of aging knowledge environment : SAGE KE 20040317 |
| Tracking variations in nicotinamide cofactors extracted from cultured cells using capillary electrophoresis with multiphoton excitation of fluorescence. | Analytical biochemistry 20040315 |
| Nicotinamide suppresses hyperphosphatemia in hemodialysis patients. | Kidney international 20040301 |
| Enhanced production and action of cyclic ADP-ribose during oxidative stress in small bovine coronary arterial smooth muscle. | Microvascular research 20040301 |
| Alterations in vascular endothelial function in the aorta and mesenteric artery in type II diabetic rats. | Canadian journal of physiology and pharmacology 20040301 |
| Preclinical studies on how to deal with patient intolerance to nicotinamide and carbogen. | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20040301 |
| Scientific community. Aging research's family feud. | Science (New York, N.Y.) 20040227 |
| Synthesis and utility of 14C-labeled nicotinamide cofactors. | Analytical biochemistry 20040201 |
| Graded reoxygenation with chemical inhibition of oxidative phosphorylation improves posthypoxic recovery in murine hippocampal slices. | Journal of neuroscience research 20040201 |
| Antidepressant-like effect of nicotinamide adenine dinucleotide in the forced swim test in rats. | Pharmacology, biochemistry, and behavior 20040201 |
| Neuroprotective effects of nicotinamide after experimental spinal cord injury. | Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20040201 |
| Effects of long-term exposure to nicotinamide and sodium butyrate on growth, viability, and the function of clonal insulin secreting cells. | Endocrine research 20040201 |
| [Metabolic disturbance of tryptophan-nicotinamide conversion pathway by putative endocrine disruptors, bisphenol A and styrene monomer]. | Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20040201 |
| Toward the elucidation of the catalytic mechanism of the mono-ADP-ribosyltransferase activity of Pseudomonas aeruginosa exotoxin A. | Biochemistry 20040113 |
| Nicotinamide does not influence cytokines or exhaled NO in human experimental endotoxaemia. | Clinical and experimental immunology 20040101 |
| Use of PRZM-3 to validate a laboratory to field degradation conceptual model. | Pest management science 20040101 |
| Effects of excess nicotinamide administration on the urinary excretion of nicotinamide N-oxide and nicotinuric acid by rats. | Bioscience, biotechnology, and biochemistry 20040101 |
| Neuroprotective effect of combination of poly (ADP-ribose) polymerase inhibitor and antioxidant in middle cerebral artery occlusion induced focal ischemia in rats. | Neurological research 20040101 |
| [Nicotinic acid]. | Nihon rinsho. Japanese journal of clinical medicine 20040101 |
| Understanding and improving NADPH-dependent reactions by nongrowing Escherichia coli cells. | Biotechnology progress 20040101 |
| Extracellular inosine is modulated by H2O2 and protects sertoli cells against lipoperoxidation and cellular injury. | Free radical research 20040101 |
| Nicotinamide: a potential anti-addiction weapon. | Medical hypotheses 20040101 |
| Differentiation of human embryonic stem cells into insulin-producing clusters. | Stem cells (Dayton, Ohio) 20040101 |
| Protective effect of nicotinamide on neuronal cells under oxygen and glucose deprivation and hypoxia/reoxygenation. | Journal of biomedical science 20040101 |
| Use of mitogenic cascade blockers for treatment of C-Raf induced lung adenoma in vivo: CI-1040 strongly reduces growth and improves lung structure. | BMC cancer 20040101 |
| Nicotinamide effects oxidative burst activity of neutrophils in patients with poorly controlled type 2 diabetes mellitus. | Experimental diabesity research 20040101 |
| Poly(ADP-ribosyl)ation enhancement in brain cell nuclei is associated with diabetic neuropathy. | Journal of diabetes and its complications 20040101 |
| Pyridine-containing 6-hydrazinonicotinamide derivatives as potential bifunctional chelators for 99mTc-labeling of small biomolecules. | Bioconjugate chemistry 20040101 |
| [New data on sensibilizing therapy of alcoholic dependence]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20040101 |
| Study on the recognition of templates and their analogues on molecularly imprinted polymer using computational and conformational analysis approaches. | Journal of molecular recognition : JMR 20040101 |
| Management of bullous pemphigoid: recommendations for immunomodulatory treatments. | American journal of clinical dermatology 20040101 |
| [Antiamnesic effect of cytoflavin and neuronol in rats with ischemic impairment of cerebral circulation]. | Eksperimental'naia i klinicheskaia farmakologiia 20040101 |
| Nicotinamide relaxes vascular smooth muscle by inhibiting myosin light chain kinase-dependent signaling pathways: implications for anticancer efficacy. | Oncology research 20040101 |
| Efficacy of engineered liver tissue based on poly-L-lactic acid scaffolds and fetal mouse liver cells cultured with oncostatin M, nicotinamide, and dimethyl sulfoxide. | Tissue engineering 20040101 |
| The role of antioxidant micronutrients in the prevention of diabetic complications. | Treatments in endocrinology 20040101 |
| [Na+, K+-ATPase activity and serotonin transport in the rat brain synaptosomes fractions after acute 1,2-dichloroethane intoxication and nicotinamide administration]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20040101 |
| Mechanism of nicotinamide inhibition and transglycosidation by Sir2 histone/protein deacetylases. | The Journal of biological chemistry 20031219 |
| Differential involvement of protein kinase C in human promyelocytic leukemia cell differentiation enhanced by artemisinin. | European journal of pharmacology 20031215 |
| Rational proteomics I. Fingerprint identification and cofactor specificity in the short-chain oxidoreductase (SCOR) enzyme family. | Proteins 20031201 |
| Mild pemphigus foliaceus responding to combination therapy with niacinamide and tetracycline. | International journal of dermatology 20031201 |
| Nicotinamide inhibits endotoxin-induced monocyte tissue factor expression. | Journal of thrombosis and haemostasis : JTH 20031201 |
| Circadian rhythm in the regulation of the MAP kinase pathway--pitfall in the determination of surrogate parameters? | International journal of clinical pharmacology and therapeutics 20031201 |
| Antitumor effect and potentiation or reduction in cytotoxic drug activity in human colon carcinoma cells by the Raf kinase inhibitor (RKI) BAY 43-9006. | International journal of clinical pharmacology and therapeutics 20031201 |
| Drug-drug interaction pharmacokinetic study with the Raf kinase inhibitor (RKI) BAY 43-9006 administered in combination with irinotecan (CPT-11) in patients with solid tumors. | International journal of clinical pharmacology and therapeutics 20031201 |
| A phase I clinical and pharmacokinetic study of the Raf kinase inhibitor (RKI) BAY 43-9006 administered in combination with doxorubicin in patients with solid tumors. | International journal of clinical pharmacology and therapeutics 20031201 |
| [Prevention of type 1 diabetes: what have we achieved? What should we say and propose next to families?]. | Diabetes & metabolism 20031201 |
| Raf pathway inhibitors in oncology. | Current opinion in investigational drugs (London, England : 2000) 20031201 |
| Analysis of structural features of bis-quaternary ammonium antimicrobial agents 4,4'-(alpha,omega-polymethylenedithio)bis (1-alkylpyridinium iodide)s using computational simulation. | Bioorganic & medicinal chemistry 20031117 |
| Nicotinamide inhibits tissue factor expression in isolated human pancreatic islets: implications for clinical islet transplantation. | Transplantation 20031115 |
| Fluorometric studies of ligand-induced conformational changes of CD38. | Biochimica et biophysica acta 20031103 |
| Nicotinamide offers multiple protective mechanisms in stroke as a precursor for NAD+, as a PARP inhibitor and by partial restoration of mitochondrial function. | Pharmacology 20031101 |
| Nicorandil inhibits the release of TNFalpha from a lymphocyte cell line and peripheral blood lymphocytes. | International immunopharmacology 20031101 |
| FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis. | Cancer research 20031101 |
| [The biological role and properties of some water soluble vitamins]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20031101 |
| [Advances in the diagnosis and treatment of cerebral ischemia during the acute phase]. | Rinsho shinkeigaku = Clinical neurology 20031101 |
| Involvement of the histone deacetylase SIRT1 in chicken ovalbumin upstream promoter transcription factor (COUP-TF)-interacting protein 2-mediated transcriptional repression. | The Journal of biological chemistry 20031031 |
| Loss of p53 has site-specific effects on histone H3 modification, including serine 10 phosphorylation important for maintenance of ploidy. | Cancer research 20031015 |
| Relaxing the nicotinamide cofactor specificity of phosphite dehydrogenase by rational design. | Biochemistry 20031014 |
| Tryptophan depletion and HIV infection: a metabolic link to pathogenesis. | The Lancet. Infectious diseases 20031001 |
| Formamides mimic aldehydes and inhibit liver alcohol dehydrogenases and ethanol metabolism. | The Journal of biological chemistry 20030919 |
| The orally available spleen tyrosine kinase inhibitor 2-[7-(3,4-dimethoxyphenyl)-imidazo[1,2-c]pyrimidin-5-ylamino]nicotinamide dihydrochloride (BAY 61-3606) blocks antigen-induced airway inflammation in rodents. | The Journal of pharmacology and experimental therapeutics 20030901 |
| Origin and characteristics of an unusual pyridine nucleotide accumulating in erythrocytes: positive correlation with degree of renal failure. | Clinica chimica acta; international journal of clinical chemistry 20030901 |
| Interactions between transhydrogenase and thio-nicotinamide Analogues of NAD(H) and NADP(H) underline the importance of nucleotide conformational changes in coupling to proton translocation. | The Journal of biological chemistry 20030829 |
| Efficient synthesis of 2-aryl-6-chloronicotinamides via PXPd2-catalyzed regioselective Suzuki coupling. | Organic letters 20030821 |
| The amide rotational barriers in picolinamide and nicotinamide: NMR and ab initio studies. | Journal of the American Chemical Society 20030820 |
| Thermodynamics and kinetics of the hydride-transfer cycles for 1-aryl-1,4-dihydronicotinamide and its 1,2-dihydroisomer. | Chemistry (Weinheim an der Bergstrasse, Germany) 20030818 |
| Sir2 regulation by nicotinamide results from switching between base exchange and deacetylation chemistry. | Biochemistry 20030812 |
| Nicotinamide attenuates focal ischemic brain injury in rats: with special reference to changes in nicotinamide and NAD+ levels in ischemic core and penumbra. | Neurochemical research 20030801 |
| Are poly(ADP-ribosyl)ation by PARP-1 and deacetylation by Sir2 linked? | BioEssays : news and reviews in molecular, cellular and developmental biology 20030801 |
| Nicotinamide: a potential addition to the anti-psoriatic weaponry. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030801 |
| Electrochemical monitoring of the interaction of doxorubicin with nicotinamide and Fe(III) ions under aerobic and anaerobic conditions. | Bioelectrochemistry (Amsterdam, Netherlands) 20030801 |
| Effects of transferrin on the growth and proliferation of porcine hepatocytes: a comparison with epidermal growth factor and nicotinamide. | Chinese medical journal 20030801 |
| Expression of CD38 in human promyelocytic leukemia HL-60 cell line during differentiation by niacin-related compounds. | Bioscience, biotechnology, and biochemistry 20030801 |
| Nicotinamide induces both proliferation and differentiation of embryonic stem cells into insulin-producing cells. | Transplantation proceedings 20030801 |
| Involvement of poly(ADP-ribose) synthetase in acoustic trauma of the cochlea. | The Tohoku journal of experimental medicine 20030801 |
| Regulation of c-Raf-1: therapeutic implications. | Clinical advances in hematology & oncology : H&O 20030801 |
| Poly (ADP-ribose) polymerase inhibition prevents spontaneous and recurrent autoimmune diabetes in NOD mice by inducing apoptosis of islet-infiltrating leukocytes. | Diabetes 20030701 |
| Possible role of nicaraven in neuroprotective effect on hippocampal slice culture. | Canadian journal of physiology and pharmacology 20030701 |
| Discovery of substituted N-phenyl nicotinamides as potent inducers of apoptosis using a cell- and caspase-based high throughput screening assay. | Journal of medicinal chemistry 20030605 |
| Nicotinamide: a jack of all trades (but master of none?). | Intensive care medicine 20030601 |
| Nicotinamide increases systemic vascular resistance in ovine endotoxemia. | Intensive care medicine 20030601 |
| Effect of combining nicotinamide as a PARS-inhibitor with selective iNOS blockade during porcine endotoxemia. | Intensive care medicine 20030601 |
| Reduced tubular cation transport in diabetes: prevented by ACE inhibition. | Kidney international 20030601 |
| The effect of tertiary butylhydroperoxide and nicotinamide on human cortical neurons. | Neurotoxicology 20030601 |
| Concurrent follicular dysplasia and interface dermatitis in Boxer dogs. | Veterinary dermatology 20030601 |
| Ischemic preconditioning and nicotinamide in spinal cord protection in an experimental model of transient aortic occlusion. | European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20030601 |
| Functional rescue of N-methyl-N-nitrosourea-induced retinopathy by nicotinamide in Sprague-Dawley rats. | Current eye research 20030601 |
| BAY-43-9006 Bayer/Onyx. | Current opinion in investigational drugs (London, England : 2000) 20030601 |
| Tinnitus. | Clinical evidence 20030601 |
| Structures of shikimate dehydrogenase AroE and its Paralog YdiB. A common structural framework for different activities. | The Journal of biological chemistry 20030523 |
| Longevity research. Single signal unites treatments that prolong life. | Science (New York, N.Y.) 20030509 |
| Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae. | Nature 20030508 |
| The effect of poly (adenosine diphosphate-ribose) polymerase inhibitors on biochemical changes in testicular ischemia-reperfusion injury. | The Journal of urology 20030501 |
| N-methyl-2-pyridone-5-carboxamide: a novel uremic toxin? | Kidney international. Supplement 20030501 |
| Downregulation of NF-kappaB activation in human keratinocytes by melanogenic inhibitors. | Journal of dermatological science 20030501 |
| Nicotinamide: necessary nutrient emerges as a novel cytoprotectant for the brain. | Trends in pharmacological sciences 20030501 |
| Activity of the Raf kinase inhibitor BAY 43-9006 in patients with advanced solid tumors. | Clinical colorectal cancer 20030501 |
| Nicotinamide-containing sunscreens for use in Australasian countries and cancer-provoking conditions. | Medical hypotheses 20030401 |
| Radiotherapy and chemotherapy with or without carbogen and nicotinamide in inoperable biopsy-proven glioblastoma multiforme. | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20030401 |
| Dissolution, bioavailability and ulcerogenic studies on piroxicam-nicotinamide solid dispersion formulations. | Bollettino chimico farmaceutico 20030401 |
| A case of co-incident phenylketonuria, pemphigus foliaceus, and tinea amiantacea treated with tetracycline and nicotinamide. | Journal of drugs in dermatology : JDD 20030401 |
| Amino acid residues in the nicotinamide binding site contribute to catalysis by horse liver alcohol dehydrogenase. | Biochemistry 20030318 |
| Graded sensitiveness of the various retinal neuron populations on the glyoxal-mediated formation of advanced glycation end products and ways of protection. | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20030301 |
| Intervening before the onset of Type 1 diabetes: baseline data from the European Nicotinamide Diabetes Intervention Trial (ENDIT). | Diabetologia 20030301 |
| Effect of nicotinamide on the photolysis of cyanocobalamin in aqueous solution. | Journal of pharmaceutical and biomedical analysis 20030226 |
| Nicotinamide: an oral antimicrobial agent with activity against both Mycobacterium tuberculosis and human immunodeficiency virus. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20030215 |
| Developments in radiotherapy and adjuvant chemotherapy for head and neck cancer. | Clinical otolaryngology and allied sciences 20030201 |
| Loss of beta-cell mass leads to a reduction of pulse mass with normal periodicity, regularity and entrainment of pulsatile insulin secretion in Göttingen minipigs. | Diabetologia 20030201 |
| N-cyanomethyl-2-chloroisonicotinamide induces systemic acquired resistance in arabidopsis without salicylic acid accumulation. | Bioscience, biotechnology, and biochemistry 20030201 |
| Augmented lipopolysaccharide-induction of the histamine-forming enzyme in streptozotocin-induced diabetic mice. | Biochimica et biophysica acta 20030120 |
| Measurements of insulin secretory capacity and glucose tolerance to predict pancreatic beta-cell mass in vivo in the nicotinamide/streptozotocin Göttingen minipig, a model of moderate insulin deficiency and diabetes. | Diabetes 20030101 |
| Influence of short-term antioxidant supplementation on macular function in age-related maculopathy: a pilot study including electrophysiologic assessment. | Ophthalmology 20030101 |
| Nicotinamide is a potent inhibitor of proinflammatory cytokines. | Clinical and experimental immunology 20030101 |
| Nicotinamide prevents the long-term effects of perinatal asphyxia on basal ganglia monoamine systems in the rat. | Experimental brain research 20030101 |
| The effect of nicotinamide & hyperoxic gases on blood glucose. | Advances in experimental medicine and biology 20030101 |
| A retrospective study regarding the treatment of lupoid onychodystrophy in 30 dogs and literature review. | Journal of the American Animal Hospital Association 20030101 |
| Nicotinamide- and caspase-mediated inhibition of poly(ADP-ribose) polymerase are associated with p53-independent cell cycle (G2) arrest and apoptosis. | Molecular and cellular biochemistry 20030101 |
| [Structural-functional damage to cellular membranes in deficiency of vitamins A, E, B2, B6, PP in children with calculous pyelonephritis]. | Urologiia (Moscow, Russia : 1999) 20030101 |
| Cyclic ADP-ribose contributes to contraction and Ca2+ release by M1 muscarinic receptor activation in coronary arterial smooth muscle. | Journal of vascular research 20030101 |
| Bioenergetic approaches for neuroprotection in Parkinson's disease. | Annals of neurology 20030101 |
| Effect of vitamin C, E-acetate and beta-carotene on the cytostatic activity of nicotinamide (vitamin B3). | In vivo (Athens, Greece) 20030101 |
| Enhancement of cell viability in cryopreserved rat vascular grafts by administration of regenerating gene (REG) inducers. | Journal of vascular research 20030101 |
| 1-Methylnicotinamide: a potent anti-inflammatory agent of vitamin origin. | Polish journal of pharmacology 20030101 |
| Interventions for bullous pemphigoid. | The Cochrane database of systematic reviews 20030101 |
| Polymorphic light eruption. | Dermatologic therapy 20030101 |
| Potential urinary and plasma biomarkers of peroxisome proliferation in the rat: identification of N-methylnicotinamide and N-methyl-4-pyridone-3-carboxamide by 1H nuclear magnetic resonance and high performance liquid chromatography. | Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20030101 |
| Human amnion-isolated cells normalize blood glucose in streptozotocin-induced diabetic mice. | Cell transplantation 20030101 |
| [State of GABA-benzodiazepine receptor complex in diabetic neuropathy: effect of nicotinamide and nicotinoyl-GABA]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20030101 |
| Unexpected interactions between nicotinamide and CPT-11 in a rhabdomyosarcoma tumor model. | Anticancer research 20030101 |
| Modulation of the activation of extracellular signal-regulated kinase (ERK) and the production of inflammatory mediators by ADP-ribosylation inhibitors. | Biological chemistry 20030101 |
| [Neuroprotective effect of cytoflavin in closed craniocerebral trauma]. | Eksperimental'naia i klinicheskaia farmakologiia 20030101 |
| Oxidative stress and Graves' ophthalmopathy: in vitro studies and therapeutic implications. | BioFactors (Oxford, England) 20030101 |
| Evidence for a causal role of CD38 expression in granulocytic differentiation of human HL-60 cells. | The Journal of biological chemistry 20021220 |
| Isulinotropic properties of Nigella sativa oil in Streptozotocin plus Nicotinamide diabetic hamster. | Research in veterinary science 20021201 |
| [Oral pemphigus vulgaris. Successful treatment with minocycline and nicotinamide]. | Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20021201 |
| Pimonidazole binding and tumor vascularity predict for treatment outcome in head and neck cancer. | Cancer research 20021201 |
| ARCON: a novel biology-based approach in radiotherapy. | The Lancet. Oncology 20021201 |
| Simultaneous determination of nicotinamide, pyridoxine hydrochloride, thiamine mononitrate and riboflavin in multivitamin with minerals tablets by reversed-phase ion-pair high performance liquid chromatography. | Biomedical chromatography : BMC 20021201 |
| Antiepiligrin cicatricial pemphigoid of the larynx successfully treated with a combination of tetracycline and niacinamide. | Archives of otolaryngology--head & neck surgery 20021201 |
| Convergence of calcium signaling pathways of pathogenic elicitors and abscisic acid in Arabidopsis guard cells. | Plant physiology 20021201 |
| ERK1/2 phosphorylation: a biomarker analysis within a phase I study with the new Raf kinase inhibitor BAY43-9006. | International journal of clinical pharmacology and therapeutics 20021201 |
| Results of phase I pharmacokinetic and pharmacodynamic studies of the Raf kinase inhibitor BAY 43-9006 in patients with solid tumors. | International journal of clinical pharmacology and therapeutics 20021201 |
| Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1. | The Journal of biological chemistry 20021122 |
| The effects of nicotinamide on energy metabolism following transient focal cerebral ischemia in Wistar rats. | Neuroscience letters 20021122 |
| Nicotinamide therapy protects against both necrosis and apoptosis in a stroke model. | Pharmacology, biochemistry, and behavior 20021101 |
| Ubiquinone and nicotinamide treatment of patients with the 3243A-->G mtDNA mutation. | Neurology 20021022 |
| Identification of N1-methyl-2-pyridone-5-carboxamide and N1-methyl-4-pyridone-5-carboxamide as components in urine extracts of individuals consuming coffee. | Journal of pharmaceutical and biomedical analysis 20021015 |
| Chronic exposure to free fatty acids or high glucose induces apoptosis in rat pancreatic islets: possible role of oxidative stress. | Metabolism: clinical and experimental 20021001 |
| [Info-congress. Study of the prevention of type 1 diabetes with nicotinamide: positive lessons of a negative clinical trial (ENDIT)]. | Revue medicale de Liege 20021001 |
| Biochemical stabilization enhances red blood cell recovery and stability following cryopreservation. | Cryobiology 20021001 |
| Targeting intracellular signal transduction. A new paradigm for a brave new world of molecularly targeted therapeutics. | Hematology/oncology clinics of North America 20021001 |
| Functional maturation of fetal porcine beta-cells by glucagon-like peptide 1 and cholecystokinin. | Endocrinology 20020901 |
| Successful treatment with doxycycline and nicotinamide of two cases of persistent pemphigoid gestationis. | The Journal of dermatological treatment 20020901 |
| [Pharmacotherapies for type 1 diabetes mellitus]. | Nihon rinsho. Japanese journal of clinical medicine 20020901 |
| Pellagra and skin. | International journal of dermatology 20020801 |
| Determination of nicotinamide and 4-aminobenzoic acid in pharmaceutical preparation by LC. | Journal of pharmaceutical and biomedical analysis 20020720 |
| LC/MS analysis of NAD biosynthesis using stable isotope pyridine precursors. | Analytical biochemistry 20020715 |
| Effect of stimulators such as GLP-1, PACAP, and nicotinamide on glucose-stimulated insulin secretion from porcine pancreatic endocrine cells in long-term culture. | Pancreas 20020701 |
| Chloroisonicotinamide derivative induces a broad range of disease resistance in rice and tobacco. | Plant & cell physiology 20020701 |
| Nicotinamide is not a substrate of the facilitative hexose transporter GLUT1. | Biochemistry 20020625 |
| Simultaneous determination of riboflavin phosphate and other ingredients in a multivitamin pharmaceutical preparation by on-line automated LC coupled with pre-column immobilized enzyme reactor. | Journal of pharmaceutical and biomedical analysis 20020620 |
| Cooperative ligation, back-bonding, and possible pyridine-pyridine interactions in tetrapyridine-vanadium(II): a visible and X-ray spectroscopic study. | Inorganic chemistry 20020617 |
| A melanocyte-keratinocyte coculture model to assess regulators of pigmentation in vitro. | Analytical biochemistry 20020615 |
| Mild streptozotocin diabetes in the Göttingen minipig. A novel model of moderate insulin deficiency and diabetes. | American journal of physiology. Endocrinology and metabolism 20020601 |
| Enhancement of muscular performance by a coformulation of propionyl-L-carnitine, coenzyme Q10, nicotinamide, riboflavin and pantothenic acid in the rat. | Physiology & behavior 20020601 |
| Impact of integrin-matrix matching and inhibition of apoptosis on the survival of purified human beta-cells in vitro. | Diabetologia 20020601 |
| Pharmacology and toxicity of nicotinamide combined with domperidone during fractionated radiotherapy. | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20020601 |
| Acute effects of vascular modifying agents in solid tumors assessed by noninvasive laser Doppler flowmetry and near infrared spectroscopy. | Neoplasia (New York, N.Y.) 20020501 |
| An efficient chemical synthesis of nicotinamide riboside (NAR) and analogues. | Bioorganic & medicinal chemistry letters 20020422 |
| Productive trapping of NAD-type radicals. Non-biomimetic reduction of pyridinium salts. | Chemical communications (Cambridge, England) 20020421 |
| Nicotinamide and ketamine reduce infarct volume and DNA fragmentation in rats after brain ischemia and reperfusion. | Neuroscience letters 20020412 |
| Halothane potentiation of hydrogen peroxide-induced inhibition of surfactant synthesis: the role of type II cell energy status. | Anesthesia and analgesia 20020401 |
| [Elucidation of paraquat poisoning mechanism and development of the neuronal death model]. | Nihon eiseigaku zasshi. Japanese journal of hygiene 20020401 |
| Influence of long-term treatment with tetracycline and niacinamide on antibody production in dogs with discoid lupus erythematosus. | American journal of veterinary research 20020401 |
| Chemical synthesis of benzamide riboside. | Current medicinal chemistry 20020401 |
| The chemistry of nicotinamide adenine dinucleotide (NAD) analogues containing C-nucleosides related to nicotinamide riboside. | Current medicinal chemistry 20020401 |
| Use of in vitro-generated, stem cell-derived islets to cure type 1 diabetes: how close are we? | Annals of the New York Academy of Sciences 20020401 |
| IL-1beta expression in islet cells of the NOD mouse and its spatial relationship to beta cells and inducible nitric oxide synthase. | Annals of the New York Academy of Sciences 20020401 |
| Nicorandil inhibits degranulation and TNF-alpha release from RBL-2H3 cells. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20020401 |
| Eptastigmine, nicotinamide and nicotinic acid determination using an inhibition enzyme sensor; application to pharmaceutical analysis. | Annali di chimica 20020401 |
| Bioavailability of reduced nicotinamide-adenine-dinucleotide (NADH) in the central nervous system of the anaesthetized rat measured by laser-induced fluorescence spectroscopy. | Pharmacology & toxicology 20020401 |
| Medicinal chemistry of nicotinamide in the treatment of ischemia and reperfusion. | Mini reviews in medicinal chemistry 20020401 |
| Delayed treatment with nicotinamide (vitamin B3) reduces the infarct volume following focal cerebral ischemia in spontaneously hypertensive rats, diabetic and non-diabetic Fischer 344 rats. | Brain research 20020322 |
| ARCON: experience in 215 patients with advanced head-and-neck cancer. | International journal of radiation oncology, biology, physics 20020301 |
| Protective effects of poly (ADP-ribose) synthase inhibitors on digoxin-induced cardiotoxicity in guinea-pig isolated hearts. | Pharmacological research 20020301 |
| IFN gamma/TNF alpha synergism in MHC class II induction: effect of nicotinamide on MHC class II expression but not on islet-cell apoptosis. | Diabetologia 20020301 |
| Nicotinamide prevents N-methyl-N-nitrosourea-induced photoreceptor cell apoptosis in Sprague-Dawley rats and C57BL mice. | Experimental eye research 20020301 |
| Reactivity of the B-H Bond in tris(pyrazolyl)hydroborato zinc complexes: unexpected example of zinc hydride formation in a protic solvent and its relevance towards hydrogen transfer to NAD(+) mimics by tris(pyrazolyl)hydroborato zinc complexes in alcoholic media. | Inorganic chemistry 20020225 |
| Crystallographic studies on human BST-1/CD157 with ADP-ribosyl cyclase and NAD glycohydrolase activities. | Journal of molecular biology 20020222 |
| Therapeutic window for nicotinamide following transient focal cerebral ischemia. | Neuroreport 20020211 |
| Concurrent quantification of quinolinic, picolinic, and nicotinic acids using electron-capture negative-ion gas chromatography-mass spectrometry. | Analytical biochemistry 20020201 |
| Possible role of 1-methylnicotinamide in the pathogenesis of Parkinson's disease. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20020201 |
| Accumulation of plasma N-methyl-2-pyridone-5-carboxamide in patients with chronic renal failure. | Molecular and cellular biochemistry 20020201 |
| High-dosed nicotinamide decreases early graft failure after pig to nude rat intraportal islet transplantation. | Transplantation 20020115 |
| Sensitivity of HaCat keratinocytes to diabetogenic toxins. | Biochemical pharmacology 20020115 |
| HIV-1 escape from a small molecule, CCR5-specific entry inhibitor does not involve CXCR4 use. | Proceedings of the National Academy of Sciences of the United States of America 20020108 |
| Inducible protective processes in animal systems. X. Influence of nicotinamide in methyl methanesulfonate-adapted mouse bone marrow cells. | Mutagenesis 20020101 |
| Pharmacological intakes of niacin increase bone marrow poly(ADP-ribose) and the latency of ethylnitrosourea-induced carcinogenesis in rats. | The Journal of nutrition 20020101 |
| The modification of human tumour blood flow using pentoxifylline, nicotinamide and carbogen. | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20020101 |
| Control of radioactivity pharmacokinetics of 99mTc-HYNIC-labeled polypeptides derivatized with ternary ligand complexes. | Bioconjugate chemistry 20020101 |
| Nicotinamide modulates mitochondrial membrane potential and cysteine protease activity during cerebral vascular endothelial cell injury. | Journal of vascular research 20020101 |
| How to re-energise old mitochondria without shooting yourself in the foot. | Biogerontology 20020101 |
| [Use of cytoflavin for correction of complications of myocardial infarction]. | Eksperimental'naia i klinicheskaia farmakologiia 20020101 |
| Nicotinamide and structurally related compounds show halting activity against zoospores of the phytopathogenic fungus Aphanomyces cochlioides. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20020101 |
| Synthesis and asymmetric reducing performance of chitin/dihydronicotinamide conjugates having glycine or L-leucine spacer arms. | Biomacromolecules 20020101 |
| 99mTc-Labeling of a hydrazinonicotinamide-conjugated LTB(4) receptor antagonist useful for imaging infection and inflammation. | Bioconjugate chemistry 20020101 |
| The importance of tumor metabolism in cancer prognosis and therapy; pre-clinical studies on rodent tumors with agents that improve tumor oxygenation. | Advances in enzyme regulation 20020101 |
| Rapid determination of thiamine, riboflavin, pyridoxine, and niacinamide in infant formulas by liquid chromatography. | Journal of AOAC International 20020101 |
| N-methylation underlying Parkinson's disease. | Neurotoxicology and teratology 20020101 |
| [Effect of nicotinamide adenine dinucleotide on the serotoninergic mediator system in the rat brain during 3-acetylpyridine administration]. | Voprosy meditsinskoi khimii 20020101 |
| BAY 43-9006: early clinical data in patients with advanced solid malignancies. | Current pharmaceutical design 20020101 |
| BAY 43-9006: preclinical data. | Current pharmaceutical design 20020101 |
| Enhanced in vitro maturation of fetal mouse liver cells with oncostatin M, nicotinamide, and dimethyl sulfoxide. | Cell transplantation 20020101 |
| Nicotinamide 'protects' resting lymphocytes exposed to hydrogen peroxide from necrosis but not from apoptosis. | Cell biology and toxicology 20020101 |
| [Changes in vitamins intake in overweight and obese adults after low-energy diets]. | Roczniki Panstwowego Zakladu Higieny 20020101 |
| [Oxidative stress correction by nicotinamide and nicotynol-GABA in diabetic neuropathy]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20020101 |
| [Nitrite reductase activity of deoxyhemoglobin in diabetes and its correction by nicotinamide]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20020101 |
| Bioorganometallic chemistry. 13. Regioselective reduction of NAD(+) models, 1-benzylnicotinamde triflate and beta-nicotinamide ribose-5'-methyl phosphate, with in situ generated [CpRh(Bpy)H](+): structure-activity relationships, kinetics, and mechanistic aspects in the formation of the 1,4-NADH derivatives. | Inorganic chemistry 20011217 |
| Rapid reversion of aging phenotypes by nicotinamide through possible modulation of histone acetylation. | Cellular and molecular life sciences : CMLS 20011201 |
| [Neuroprotective therapy for the treatment of acute ischemic stroke]. | Rinsho shinkeigaku = Clinical neurology 20011201 |
| Dynamics of intracellular calcium and free radical production during ischemia in pyramidal neurons. | Free radical biology & medicine 20011115 |
| Characterization of hydride transfer to flavin adenine dinucleotide in neuronal nitric oxide synthase reductase domain: geometric relationship between the nicotinamide and isoalloxazine rings. | Archives of biochemistry and biophysics 20011101 |
| NAD degradation and regulation of CD38 expression by human monocytes/macrophages. | European journal of biochemistry 20011101 |
| A severe persistent case of recurrent pemphigoid gestationis successfully treated with minocycline and nicotinamide. | Clinical and experimental dermatology 20011101 |
| Influence of nicotinamide on the radiosensitivity of normal and goitrous thyroid in the rat. | Thyroid : official journal of the American Thyroid Association 20011101 |
| Rapid calmodulin-dependent interdomain electron transfer in neuronal nitric-oxide synthase measured by pulse radiolysis. | The Journal of biological chemistry 20011026 |
| Negative control of p53 by Sir2alpha promotes cell survival under stress. | Cell 20011019 |
| Effect of nicotinamide on the properties of aqueous HPMC solutions. | International journal of pharmaceutics 20010911 |
| Metabolism of NAD+ in nuclei of Saccharomyces cerevisiae during stimulation of its biosynthesis by nicotinamide. | Biochemistry. Biokhimiia 20010901 |
| X-Ray crystal structures of Candida albicans dihydrofolate reductase: high resolution ternary complexes in which the dihydronicotinamide moiety of NADPH is displaced by an inhibitor. | Journal of medicinal chemistry 20010830 |
| [Analysis of amino acids and vitamins in ginkgo biloba leaves]. | Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University 20010828 |
| NADPH-cytochrome P450 oxidoreductase. Structural basis for hydride and electron transfer. | The Journal of biological chemistry 20010803 |
| Ca(2+)-calmodulin antagonist chlorpromazine and poly(ADP-ribose) polymerase modulators 4-aminobenzamide and nicotinamide influence hepatic expression of BCL-XL and P53 and protect against acetaminophen-induced programmed and unprogrammed cell death in mice. | Free radical biology & medicine 20010801 |
| Sulfur-rich zinc chemistry: new tris(thioimidazolyl)hydroborate ligands and their zinc complex chemistry related to the structure and function of alcohol dehydrogenase. | Inorganic chemistry 20010730 |
| Intramolecular electron transfer from c heme to d1 heme in bacterial cytochrome cd1 nitrite reductase occurs over the same distances at very different rates depending on the source of the enzyme. | Biochemistry 20010724 |
| Allosteric activation of pyruvate kinase via NAD+ in rat liver cells. | European journal of biochemistry 20010701 |
| Response of chronic bullous dermatosis of childhood to a combination of dapsone and nicotinamide. | Journal of the European Academy of Dermatology and Venereology : JEADV 20010701 |
| Probing catalysis by Escherichia coli dTDP-glucose-4,6-dehydratase: identification and preliminary characterization of functional amino acid residues at the active site. | Biochemistry 20010605 |
| Rapid imaging of experimental colitis with (99m)Tc-interleukin-8 in rabbits. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20010601 |
| Delayed multidose treatment with nicotinamide extends the degree and duration of neuroprotection by reducing infarction and improving behavioral scores up to two weeks following transient focal cerebral ischemia in Wistar rats. | Annals of the New York Academy of Sciences 20010601 |
| Immunoexpression of interleukin-1beta in pancreatic islets of NOD mice during cyclophosphamide-accelerated diabetes: co-localization in macrophages and endocrine cells and its attenuation with oral nicotinamide. | The Histochemical journal 20010601 |
| Characterization of the hydroxypropylmethylcellulose-nicotinamide binary system. | International journal of pharmaceutics 20010521 |
| p38 activation is required upstream of potassium current enhancement and caspase cleavage in thiol oxidant-induced neuronal apoptosis. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20010515 |
| Effects of the interaction between carbogen and nicotinamide on R3230 Ac tumor blood flow in Fischer 344 rats. | Radiation research 20010501 |
| Inducible protective processes in animal systems: VIII. Enhancement of adaptive response by nicotinamide. | Mutagenesis 20010501 |
| Dietary vitamin K1 requirement and comparison of biopotency of different vitamin K sources for young turkeys. | Poultry science 20010501 |
| Enhanced maturation of porcine neonatal pancreatic cell clusters with growth factors fails to improve transplantation outcome. | Transplantation 20010427 |
| Metabolic and functional studies on isolated islets in a new rat model of type 2 diabetes. | Molecular and cellular endocrinology 20010425 |
| Dynamics of protein ligand binding on multiple time scales: NADH binding to lactate dehydrogenase. | Biochemistry 20010403 |
| Photodynamic therapy with hypericin in a mouse P388 tumor model: vascular effects determine the efficacy. | International journal of oncology 20010401 |
| Improvement of tumor oxygenation by mild hyperthermia. | Radiation research 20010401 |
| The metabolism of nicotinamide in human liver cirrhosis: a study on N-methylnicotinamide and 2-pyridone-5-carboxamide production. | The American journal of gastroenterology 20010401 |
| Photodynamic therapy for malignant mesothelioma: preclinical studies for optimization of treatment protocols. | Photochemistry and photobiology 20010401 |
| The IL-8 release from cultured human keratinocytes, mediated by antibodies to bullous pemphigoid autoantigen 180, is inhibited by dapsone. | Clinical and experimental immunology 20010401 |
| Photochemical generation of cyclopentadienyliron dicarbonyl anion by a nicotinamide adenine dinucleotide dimer analogue. | Inorganic chemistry 20010312 |
| [A case of pemphigus foliaceus associated with bullous impetigo successfully treated with tetracycline and nicotinamide]. | Journal of UOEH 20010301 |
| [Successful therapy with tetracycline and nicotinamide in cicatricial pemphigoid]. | Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20010301 |
| Anisotropic rotational diffusion in model-free analysis for a ternary DHFR complex. | Journal of biomolecular NMR 20010301 |
| Effects of nicotinamide, an inhibitor of PARS activity, on gut and liver O2 exchange and energy metabolism during hyperdynamic porcine endotoxemia. | Intensive care medicine 20010301 |
| Fluorometric determination of N-nitroso-N-methylurea with nicotinamide and acetophenone. | Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20010301 |
| NAD+ inhibits the self-splicing of the group I intron. | Biochemical and biophysical research communications 20010216 |
| Oxidative changes in brain pyridine nucleotides and neuroprotection using nicotinamide. | Biochimica et biophysica acta 20010216 |
| Escherichia coli O18:K1:H7 isolates from patients with acute cystitis and neonatal meningitis exhibit common phylogenetic origins and virulence factor profiles. | The Journal of infectious diseases 20010201 |
| Farnesol oxidation in insects: evidence that the biosynthesis of insect juvenile hormone is mediated by a specific alcohol oxidase. | Insect biochemistry and molecular biology 20010201 |
| Canine symmetrical lupoid onychodystrophy: a retrospective study with particular reference to management. | The Journal of small animal practice 20010201 |
| An old but simple and efficient method to elucidate the oxidation mechanism of NAD(P)H model 1-Aryl-1,4-dihydronicotinamides by cations 2-methyl-5-nitroisoquinolium, tropylium, and xanthylium in aqueous solution. | The Journal of organic chemistry 20010126 |
| Sorption and desorption studies on chitin gels. | International journal of biological macromolecules 20010110 |
| Fractionated irradiation combined with carbogen breathing and nicotinamide of two human glioblastomas grafted in nude mice. | Radiation research 20010101 |
| Effects of nicotinamide coenzymes on the stability of enzyme activities and proteins in niacin-deficient quail tissues against trypsin treatment. | Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20010101 |
| Validation of an HPLC method for the determination of urinary and plasma levels of N1-methylnicotinamide, an endogenous marker of renal cationic transport and plasma flow. | Journal of pharmaceutical and biomedical analysis 20010101 |
| Rat ventral prostate xanthine oxidase bioactivation of ethanol to acetaldehyde and 1-hydroxyethyl free radicals: analysis of its potential role in heavy alcohol drinking tumor-promoting effects. | Teratogenesis, carcinogenesis, and mutagenesis 20010101 |
| Vitamin requirements of the cultured flesh fly cells, Sarcophaga peregrina (Diptera, Sarcophagidae). | Archives of insect biochemistry and physiology 20010101 |
| Non-enzymatic reduction of aliphatic tertiary amine N-oxides mediated by the haem moiety of cytochrome P450. | Xenobiotica; the fate of foreign compounds in biological systems 20010101 |
| Molecularly imprinted polymers from nicotinamide and its positional isomers. | Journal of molecular recognition : JMR 20010101 |
| Update on major trials for the prevention of type 1 diabetes mellitus: the American Diabetes Prevention Trial (DPT-1) and the European Nicotinamide Diabetes Intervention Trial (ENDIT). | Journal of pediatric endocrinology & metabolism : JPEM 20010101 |
| The influence of excipients on the stability of the moisture sensitive drugs aspirin and niacinamide: comparison of tablets containing lactose monohydrate with tablets containing anhydrous lactose. | Pharmaceutical development and technology 20010101 |
| Increased plasma tryptophan in HIV-infected patients treated with pharmacologic doses of nicotinamide. | Nutrition (Burbank, Los Angeles County, Calif.) 20010101 |
| 99mTc-labeling of a hydrazinonicotinamide-conjugated vitronectin receptor antagonist useful for imaging tumors. | Bioconjugate chemistry 20010101 |
| Induction of oxidative stress by homocyst(e)ine impairs endothelial function. | Journal of cellular biochemistry 20010101 |
| In vitro and in vivo inhibition of telomerase activity from Chinese hamster V79 cells. | Indian journal of biochemistry & biophysics 20010101 |
| Tandem mass spectrometric accurate mass performance of time-of-flight and Fourier transform ion cyclotron resonance mass spectrometry: a case study with pyridine derivatives. | Rapid communications in mass spectrometry : RCM 20010101 |
| Autoimmune vesicles on the face and neck. A variant of Brunsting-Perry type localized bullous pemphigoid? | European journal of dermatology : EJD 20010101 |
| The protective effect of niacinamide on ischemia-reperfusion-induced liver injury. | Journal of biomedical science 20010101 |
| Tetracycline and niacinamide in the treatment of blistering skin diseases. | Clinics in dermatology 20010101 |
| Soil surface structure effect on isoproturon and diflufenican loss in runoff. | Journal of environmental quality 20010101 |
| Transience in polyion complexation between nicotinamide-modified dextran and carboxymethyl dextran during enzymatic degradation of dextran. | Journal of biomaterials science. Polymer edition 20010101 |
| The optimum dose of nicotinamide for protection of pancreatic beta-cells against the cytotoxic effect of streptozotocin in albino rat. | Journal of Ayub Medical College, Abbottabad : JAMC 20010101 |
| Cofactor diversity in biological oxidations: implications and applications. | Chemical record (New York, N.Y.) 20010101 |
| Hydratases involved in nitrile conversion: screening, characterization and application. | Chemical record (New York, N.Y.) 20010101 |
| [Correction by nicotinamide and nicotinoyl-GABA of dopamine metabolism in rat brain in experimental Parkinson's disease]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20010101 |
| Treatment of sulfur mustard (HD)-induced lung injury. | Journal of applied toxicology : JAT 20001201 |
| Tetracycline and nicotinamide for the treatment of bullous pemphigoid: our experience in Singapore. | Singapore medical journal 20000701 |
| Reduction of hydroxamic acids to the corresponding amides catalyzed by rabbit blood. | Xenobiotica; the fate of foreign compounds in biological systems 20000501 |
| Il-1-related cytokine responses of nonimmune skin cells subjected to CEES exposure with and without potential vesicant antagonists. | In vitro & molecular toxicology 20000101 |
| Prevention of cyclophosphamide-induced accelerated diabetes in the NOD mouse by nicotinamide or a soy protein-based infant formula. | International journal of experimental diabetes research 20000101 |
| Isolation and characterization of a bacterium possessing a novel aldoxime-dehydration activity and nitrile-degrading enzymes. | Archives of microbiology 19980801 |
| Specific induction of the hsr omega locus of Drosophila melanogaster by amides. | Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 19970901 |
| Sulphonylurea receptor 2B and Kir6.1 form a sulphonylurea-sensitive but ATP-insensitive K+ channel. | The Journal of physiology 19970315 |
| Polyarteritis nodosa-like inflammatory vascular changes in the pancreas and mesentery of rats treated with streptozotocin and nicotinamide. | Journal of comparative pathology 19970201 |
| Analysis of relaxation and repolarization mechanisms of nicorandil in rat mesenteric artery. | British journal of pharmacology 19961201 |
| Effects of a new calcium antagonist, CD-832, on isoproterenol-induced myocardial ischemia in dogs with partial coronary stenosis. | The Journal of pharmacology and experimental therapeutics 19960901 |
| Nonenzymatic acetolactate oxidation to diacetyl by flavin, nicotinamide and quinone coenzymes. | Biochimica et biophysica acta 19951214 |
| Exacerbation of acetaminophen hepatotoxicity by thalidomide and protection by nicotinic acid amide. | General pharmacology 19951001 |
| Nicotinamide inhibits HIV-1 in both acute and chronic in vitro infection. | Biochemical and biophysical research communications 19950525 |
| Effect of four potassium channel agonists on bupivacaine-induced toxicity in mice. | Life sciences 19950101 |
| Effects of a novel dihydropyridine calcium antagonist on venous capacitance in Wistar-Kyoto rats. | Drugs under experimental and clinical research 19940101 |
| Neuroprotection against nitric oxide injury with inhibitors of ADP-ribosylation. | Neuroreport 19931213 |
| Effect of KRN2391, a novel vasodilator, on various experimental anginal models in rats. | Japanese journal of pharmacology 19930901 |
| Protection by nicorandil against the dysfunction of the central vagal baroreflex system following transient global cerebral ischaemia in dogs. | British journal of pharmacology 19930801 |
| Nicorandil. A review of its pharmacology and therapeutic efficacy in angina pectoris. | Drugs 19921001 |
| Molecular mechanism of action of nicorandil. | Journal of cardiovascular pharmacology 19920101 |
| Pharmacokinetic profile of nicorandil in humans: an overview. | Journal of cardiovascular pharmacology 19920101 |
| Differentiation of 3T3-L1 pre-adipocytes induced by inhibitors of poly(ADP-ribose) polymerase and by related noninhibitory acids. | European journal of biochemistry 19890401 |
| Effect of nicotinamide on theophylline seizures in rats. | Biochemical pharmacology 19880315 |
| Inhibition of vaccinia virus replication by nicotinamide: evidence for ADP-ribosylation of viral proteins. | Virus research 19880201 |
| Streptozotocin-induced diabetes modulates the metabolic activation of chemical carcinogens. | Chemico-biological interactions 19880101 |
| [Effect of diazepam and nicotinamide on convulsive activity of various types]. | Farmakologiia i toksikologiia 19850101 |
| Enhancement of DEN initiation of liver carcinogenesis by inhibitors of NAD+ ADP ribosyl transferase in rats. | Carcinogenesis 19840701 |
| Gentamicin nephrotoxicity. I. Degree and permanence of acquired insensitivity. | The Journal of laboratory and clinical medicine 19821001 |
| [On the plurifactorial determinism of the organophosphorous-induced teratogenesis on bird embryos; trials of protection by various compounds: oximes, hydroxamic acids and nicotinamide analogs (author's transl)]. | Archives d'anatomie, d'histologie et d'embryologie normales et experimentales 19790101 |
| A pyridoxine-dependent behavioral disorder unmasked by isoniazid. | American journal of diseases of children (1960) 19780801 |
| Tumorigenic action of streptozotocin on the pancreas and kidney in male Wistar rats. | Cancer research 19780701 |
| Nephrotoxic and hepatotoxic effects of triclosan and chlorhexidine in rats. | Toxicology and applied pharmacology 19771001 |
| Exacerbation of dapsone-induced Heinz body hemolytic anemia following treatment with methylene blue. | The American journal of the medical sciences 19740501 |
| DNA synthesis inhibition, cytotoxicity and their relationship to teratogenesis following administration of a nicotinamide antagonist, aminothiadiazole, to pregnant rats. | Journal of embryology and experimental morphology 19730801 |
| A simple way of detecting pyrazinamide resistance. | Tubercle 19720601 |
| Reversible pellagra-like encephalopathy with ethionamide and cycloserine. | Tubercle 19720601 |
| [Treatment of lepromatous leprosy by ethionamide]. | Maroc medical 19720301 |
| [Neuropsychiatric incidences in antitubercular treatment consisting of isoniazid or isoniazid and ethionamide (8 cases)]. | Annales medico-psychologiques 19690701 |
| Pyrazinamide susceptibility and amidase activity of tubercle bacilli. | The American review of respiratory disease 19670301 |
| [Chemical studies the mechanism of action of isoniazid]. | Arzneimittel-Forschung 19661101 |
| Synthesis of diphosphopyridine nucleotide from nicotinamide by slices of liver. | Nature 19590704 |
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