Home Other Building Blocks Pergolide mesylate salt

Pergolide mesylate salt

CAS No.:
66104-23-2
Catalog Number:
AG00FA2F
Molecular Formula:
C20H30N2O3S2
Molecular Weight:
410.5938
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
25mg
≥95%
1 week
United States
$119
- +
50mg
≥95%
1 week
United States
$176
- +
100mg
≥95%
1 week
United States
$257
- +
250mg
≥95%
1 week
United States
$526
- +
Product Description
Catalog Number:
AG00FA2F
Chemical Name:
Pergolide mesylate salt
CAS Number:
66104-23-2
Molecular Formula:
C20H30N2O3S2
Molecular Weight:
410.5938
MDL Number:
MFCD00153859
IUPAC Name:
(6aR,9R,10aR)-9-(methylsulfanylmethyl)-7-propyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline;methanesulfonic acid
InChI:
InChI=1S/C19H26N2S.CH4O3S/c1-3-7-21-11-13(12-22-2)8-16-15-5-4-6-17-19(15)14(10-20-17)9-18(16)21;1-5(2,3)4/h4-6,10,13,16,18,20H,3,7-9,11-12H2,1-2H3;1H3,(H,2,3,4)/t13-,16-,18-;/m1./s1
InChI Key:
UWCVGPLTGZWHGS-ZORIOUSZSA-N
SMILES:
CS(=O)(=O)O.CCCN1C[C@H](CSC)C[C@H]2[C@H]1Cc1c[nH]c3c1c2ccc3
UNII:
55B9HQY616
Properties
Complexity:
480  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
3  
Defined Bond Stereocenter Count:
0
Exact Mass:
410.17g/mol
Formal Charge:
0
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
410.591g/mol
Monoisotopic Mass:
410.17g/mol
Rotatable Bond Count:
4  
Topological Polar Surface Area:
107A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
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Diagnosis and management of pergolide-induced fibrosis. Movement disorders : official journal of the Movement Disorder Society 20040601
Extensive fibromuscular dysplasia in a patient with Parkinson disease. The American journal of the medical sciences 20040601
Rapid onset of pergolide-induced pulmonary fibrosis in a patient with corticobasal degeneration. Hospital medicine (London, England : 1998) 20040601
A novel mechanism for pergolide-induced neuroprotection: inhibition of NF-kappaB nuclear translocation. Biochemical pharmacology 20040501
Efficacy of pergolide in treatment of restless legs syndrome: the PEARLS Study. Neurology 20040427
Treatment of Parkinson's disease with pergolide and relation to restrictive valvular heart disease. Lancet (London, England) 20040410
Effects of pergolide on nocturia in Parkinson's disease: three female cases selected from over 400 patients. Parkinsonism & related disorders 20040301
Predictors of impaired daytime sleep and wakefulness in patients with Parkinson disease treated with older (ergot) vs newer (nonergot) dopamine agonists. Archives of neurology 20040101
[A comparative study of efficacy of dopamine receptors agonists and catechol-O-methyltransferase in the treatment of late stages of Parkinson's disease]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20040101
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Pergolide, terguride and N,N'-spacer-linked oligomers of both interact with 5-HT2A receptors of rat tail artery. Physiological research 20040101
Plasma homocysteine levels in pergolide-treated Parkinson disease patients. Clinical neuropharmacology 20040101
Influence of the therapy with pergolide mesylate plus L-DOPA and with L-DOPA alone on serum cGMP level in PD patients. Polish journal of pharmacology 20040101
Pergolide mesylate, a dopaminergic receptor agonist, applied with L-DOPA enhances serum antioxidant enzyme activity in Parkinson disease. Clinical neuropharmacology 20040101
Valvular health disease with pergolide. Prescrire international 20031201
The pharmacokinetics of pergolide in Parkinson's disease. Current opinion in neurology 20031201
Comparing dopamine agonists in Parkinson's disease. Current opinion in neurology 20031201
Appropriate dosing of pergolide in monotherapy and adjunctive therapy in Parkinson's disease. Current opinion in neurology 20031201
Randomized, double-blind, 3-month parallel study of the effects of pramipexole, pergolide, and placebo on Parkinsonian tremor. Movement disorders : official journal of the Movement Disorder Society 20031101
[Effects of D1 and D2 dopamine receptor agonists and antagonists on cerebral ischemia/reperfusion injury]. Sheng li xue bao : [Acta physiologica Sinica] 20031025
L-DOPA-induced excessive daytime sleepiness in PD: a placebo-controlled case with MSLT assessment. Neurology 20031014
Pergolide mesylate form II. Acta crystallographica. Section C, Crystal structure communications 20031001
Heart valvular disease in patients with Parkinson's disease treated with high-dose pergolide. Neurology 20030923
[Tardive dyskinesia: pergolid, a possible therapeutic option]. Psychiatrische Praxis 20030901
Pathological gambling associated with dopamine agonist therapy in Parkinson's disease. Neurology 20030812
Pramipexole and pergolide in the treatment of depression in Parkinson's disease: a national multicentre prospective randomized study. European journal of neurology 20030701
High-sensitivity quantitation of cabergoline and pergolide using a triple-quadrupole mass spectrometer with enhanced mass-resolution capabilities. Journal of mass spectrometry : JMS 20030701
Effects of dopamine agonists bromocriptine, pergolide, cabergoline, and SKF-38393 on GDNF, NGF, and BDNF synthesis in cultured mouse astrocytes. Life sciences 20030620
Dopamine agonist therapy for hyperprolactinemia. Clinical obstetrics and gynecology 20030601
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The effect of a dopamine agonist on dysarthric speech production: a case study. Journal of communication disorders 20010101
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Clozapine for dopaminergic-induced paraphilias in Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society 19980501
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Pharmacological, hemodynamic and biochemical mechanisms involved in the blood pressure lowering effects of pergolide, in normotensive and hypertensive dogs. The Journal of pharmacology and experimental therapeutics 19851201
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