DESMETHYL LOPERAMIDE
| Title | Journal |
|---|---|
| Characterization of SAGE Mdr1a (P-gp), Bcrp, and Mrp2 knockout rats using loperamide, paclitaxel, sulfasalazine, and carboxydichlorofluorescein pharmacokinetics. | Drug metabolism and disposition: the biological fate of chemicals 20120901 |
| The influence of mass of [11C]-laniquidar and [11C]-N-desmethyl-loperamide on P-glycoprotein blockage at the blood-brain barrier. | Nuclear medicine and biology 20120101 |
| Antiepileptic drugs modulate P-glycoproteins in the brain: a mice study with (11)C-desmethylloperamide. | Epilepsy research 20110301 |
| N-desmethyl-loperamide is selective for P-glycoprotein among three ATP-binding cassette transporters at the blood-brain barrier. | Drug metabolism and disposition: the biological fate of chemicals 20100601 |
| P-glycoprotein function at the blood-brain barrier in humans can be quantified with the substrate radiotracer 11C-N-desmethyl-loperamide. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100401 |
| Human brain imaging and radiation dosimetry of 11C-N-desmethyl-loperamide, a PET radiotracer to measure the function of P-glycoprotein. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20090501 |
| P-glycoprotein function at the blood-brain barrier imaged using 11C-N-desmethyl-loperamide in monkeys. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20090101 |
| Synthesis and evaluation of [N-methyl-11C]N-desmethyl-loperamide as a new and improved PET radiotracer for imaging P-gp function. | Journal of medicinal chemistry 20081009 |
| Itraconazole, gemfibrozil and their combination markedly raise the plasma concentrations of loperamide. | European journal of clinical pharmacology 20060601 |
| Tissue distribution of loperamide and N-desmethylloperamide following a fatal overdose. | Journal of analytical toxicology 20051001 |
| Identification of an N-methyl-4-phenylpyridinium-like metabolite of the antidiarrheal agent loperamide in human liver microsomes: underlying reason(s) for the lack of neurotoxicity despite the bioactivation event. | Drug metabolism and disposition: the biological fate of chemicals 20040901 |