Home Other Building Blocks STRYCHNINE NITRATE

STRYCHNINE NITRATE

CAS No.:
66-32-0
Catalog Number:
AG00FA21
Molecular Formula:
Molecular Weight:
Pack Size
Purity
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Product Description
Catalog Number:
AG00FA21
Chemical Name:
STRYCHNINE NITRATE
CAS Number:
66-32-0
MDL Number:
MFCD00078519
IUPAC Name:
(4aR,5aS,8aR,13aS,15aS,15bR)-4a,5,5a,7,8,13a,15,15a,15b,16-decahydro-2H-4,6-methanoindolo[3,2,1-ij]oxepino[2,3,4-de]pyrrolo[2,3-h]quinolin-14-one;nitric acid
InChI:
InChI=1S/C21H22N2O2.HNO3/c24-18-10-16-19-13-9-17-21(6-7-22(17)11-12(13)5-8-25-16)14-3-1-2-4-15(14)23(18)20(19)21;2-1(3)4/h1-5,13,16-17,19-20H,6-11H2;(H,2,3,4)/t13-,16-,17-,19-,20-,21+;/m0./s1
InChI Key:
PCGVPMHGSJFFTI-ZEYGOCRCSA-N
EC Number:
200-627-1
UNII:
O642E96711
Properties
Complexity:
714  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
6  
Defined Bond Stereocenter Count:
0
Exact Mass:
397.164g/mol
Formal Charge:
0
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
397.431g/mol
Monoisotopic Mass:
397.164g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
98.8A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
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Brucine, an alkaloid from seeds of Strychnos nux-vomica Linn., represses hepatocellular carcinoma cell migration and metastasis: the role of hypoxia inducible factor 1 pathway. Toxicology letters 20131024
In vitro metabolism of brucine by human liver microsomes and its interactions with CYP substrates. Chemico-biological interactions 20130825
Preparation, characterization and tissue distribution of brucine stealth liposomes with different lipid composition. Pharmaceutical development and technology 20130101
A₁ adenosine receptor modulation of chemically and electrically evoked lumbar locomotor network activity in isolated newborn rat spinal cords. Neuroscience 20121011
Experimental and theoretical investigation of 1J(CC) and (n)J(CC) coupling constants in strychnine. Organic letters 20121005
Calcium-dependent isoforms of protein kinase C mediate glycine-induced synaptic enhancement at the calyx of Held. The Journal of neuroscience : the official journal of the Society for Neuroscience 20121003
Glycine transporter type 2 (GlyT2) inhibitor ameliorates bladder overactivity and nociceptive behavior in rats. European urology 20121001
HMBC-1,1-ADEQUATE via generalized indirect covariance: a high sensitivity alternative to n,1-ADEQUATE. Magnetic resonance in chemistry : MRC 20121001
Development of brucine-loaded microsphere/thermally responsive hydrogel combination system for intra-articular administration. Journal of controlled release : official journal of the Controlled Release Society 20120928
Inhibitory control of nociceptive responses of trigeminal spinal nucleus cells by somatosensory corticofugal projection in rat. Neuroscience 20120927
Influence of P-glycoprotein on brucine transport at the in vitro blood-brain barrier. European journal of pharmacology 20120905
Effects of brucine on bone metabolism in multiple myeloma. Molecular medicine reports 20120801
Effects of brucine on vascular endothelial growth factor expression and microvessel density in a nude mouse model of bone metastasis due to breast cancer. Chinese journal of integrative medicine 20120801
The resting transducer current drives spontaneous activity in prehearing mammalian cochlear inner hair cells. The Journal of neuroscience : the official journal of the Society for Neuroscience 20120801
Identification of the transmitter and receptor mechanisms responsible for REM sleep paralysis. The Journal of neuroscience : the official journal of the Society for Neuroscience 20120718
Anticonvulsant activity of Hedranthera barteri. Pharmaceutical biology 20120701
[The post-synaptic glycine receptor mediates in a transitory and sustained way the glycinergic inhibition in the vertebrate retina]. Revista de neurologia 20120701
Dark-adapted response threshold of OFF ganglion cells is not set by OFF bipolar cells in the mouse retina. Journal of neurophysiology 20120515
[Effect of NF-kappaB on inhibition of non-small cell lung cancer cell cyclooxygenase-2 by brucine]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120501
[Brucine chitosan thermosensitive hydrogel for intra-articular injection]. Yao xue xue bao = Acta pharmaceutica Sinica 20120501
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An activity-regulated microRNA, miR-188, controls dendritic plasticity and synaptic transmission by downregulating neuropilin-2. The Journal of neuroscience : the official journal of the Society for Neuroscience 20120418
The interaction of blood proteins with brucine. Molecular biology reports 20120401
Simultaneous analysis of strychnine and brucine and their major metabolites by liquid chromatography-electrospray ion trap mass spectrometry. Journal of analytical toxicology 20120401
[Experimental study on in vitro transdermal absorption of Shangshi Zhitong cataplasm]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120401
Opposing roles of synaptic and extrasynaptic NMDA receptor signaling in cocultured striatal and cortical neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience 20120321
A rare case of combined strychnine and propoxur toxicity from a single preparation. Clinical toxicology (Philadelphia, Pa.) 20120301
[Determination of brucine and strychnine in rat after cutaneous administration of semen strychni niosome gel by LC-MS/MS]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120301
Characterization of two mutations, M287L and Q266I, in the α1 glycine receptor subunit that modify sensitivity to alcohols. The Journal of pharmacology and experimental therapeutics 20120201
Behavioral characterization of knockin mice with mutations M287L and Q266I in the glycine receptor α1 subunit. The Journal of pharmacology and experimental therapeutics 20120201
Regulation of spinal interneuron differentiation by the paracrine action of glycine. Developmental neurobiology 20120201
Thyrotropin-releasing hormone causes a tonic excitatory postsynaptic current and inhibits the phasic inspiratory inhibitory inputs in inspiratory-inhibited airway vagal preganglionic neurons. Neuroscience 20120127
Syntheses of strychnine, norfluorocurarine, dehydrodesacetylretuline, and valparicine enabled by intramolecular cycloadditions of Zincke aldehydes. The Journal of organic chemistry 20120106
A new method for the simultaneous analysis of strychnine and brucine in Strychnos nux-vomica unprocessed and processed seeds using a carbon-paste electrode modified with multi-walled carbon nanotubes. Phytochemical analysis : PCA 20120101
Cellular mechanisms of desynchronizing effects of hypothermia in an in vitro epilepsy model. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20120101
Strychnine in amoxicillin capsules: a means of homicide. Journal of forensic and legal medicine 20120101
Anti-tumor effects of brucine immuno-nanoparticles on hepatocellular carcinoma. International journal of nanomedicine 20120101
Differentiated human midbrain-derived neural progenitor cells express excitatory strychnine-sensitive glycine receptors containing α2β subunits. PloS one 20120101
Genetic analysis of the electrophysiological response to salicin, a bitter substance, in a polyphagous strain of the silkworm Bombyx mori. PloS one 20120101
A GC-EI-MS-MS method for simultaneous determination of seven adulterants in slimming functional foods. Journal of chromatographic science 20120101
Improved pharmacokinetics and reduced toxicity of brucine after encapsulation into stealth liposomes: role of phosphatidylcholine. International journal of nanomedicine 20120101
Anticonvulsant activity of the methanolic extract of Justicia extensa T. Anders. Journal of ethnopharmacology 20111208
Pharmacokinetics of brucine after intravenous and oral administration to rats. Fitoterapia 20111201
Accurate measurement of small heteronuclear coupling constants from pure-phase α/β HSQMBC cross-peaks. Journal of magnetic resonance (San Diego, Calif. : 1997) 20111201
Safety of individual medication of Ma Qian Zi (semen strychni) based upon assessment of therapeutic effects of Guo's therapy against moderate fluorosis of bone. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 20111201
Differential roles of GABAergic and glycinergic input on FM selectivity in the inferior colliculus of the pallid bat. Journal of neurophysiology 20111101
Validation and insights of anesthetic action in an early vertebrate network: the isolated lamprey spinal cord. Anesthesia and analgesia 20111101
Onset of cholinergic efferent synaptic function in sensory hair cells of the rat cochlea. The Journal of neuroscience : the official journal of the Society for Neuroscience 20111019
Short-term synaptic plasticity regulates the level of olivocochlear inhibition to auditory hair cells. The Journal of neuroscience : the official journal of the Society for Neuroscience 20111012
Receptor agonism and antagonism of dietary bitter compounds. The Journal of neuroscience : the official journal of the Society for Neuroscience 20111012
Bidirectional plasticity of calcium-permeable AMPA receptors in oligodendrocyte lineage cells. Nature neuroscience 20111009
Glycine inhibits startle-mediating neurons in the caudal pontine reticular formation but is not involved in synaptic depression underlying short-term habituation of startle. Neuroscience research 20111001
The mGluR5 antagonist MPEP elevates accumbal dopamine and glycine levels; interaction with strychnine-sensitive glycine receptors. Addiction biology 20111001
HSQC-1,n-ADEQUATE: a new approach to long-range 13C-13C correlation by covariance processing. Magnetic resonance in chemistry : MRC 20111001
Pharmacology of intracisternal or intrathecal glycine, muscimol, and baclofen in strychnine-induced thermal hyperalgesia of mice. Journal of Korean medical science 20111001
Identification of minimal neuronal networks involved in flexor-extensor alternation in the mammalian spinal cord. Neuron 20110922
A horizontal slice preparation for examining the functional connectivity of dorsal column fibres in mouse spinal cord. Journal of neuroscience methods 20110915
Ultra-performance liquid chromatography-tandem mass spectrometric method for the determination of strychnine and brucine in mice plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110915
Identification of a cholinergic modulatory and rhythmogenic mechanism within the lamprey respiratory network. The Journal of neuroscience : the official journal of the Society for Neuroscience 20110914
Concise syntheses of strychnine and englerin A: the power of reductive cyclizations triggered by samarium iodide. Angewandte Chemie (International ed. in English) 20110816
Inhibition of human Na(v)1.5 sodium channels by strychnine and its analogs. Biochemical pharmacology 20110815
Beta-asarone inhibits synaptic inputs to airway preganglionic parasympathetic motoneurons. Respiratory physiology & neurobiology 20110815
Role of glycine receptors in glycine-induced LTD in hippocampal CA1 pyramidal neurons. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20110801
Cytotoxic and antitumor effects of brucine on Ehrlich ascites tumor and human cancer cell line. Life sciences 20110801
Glycine receptors influence radial migration in the embryonic mouse neocortex. Neuroreport 20110713
Collective synthesis of natural products by means of organocascade catalysis. Nature 20110713
Glycine inhibitory dysfunction turns touch into pain through astrocyte-derived D-serine. Pain 20110601
Convulsion-related activities of Scutellaria flavones are related to the 5,7-dihydroxyl structures. European journal of pharmacology 20110601
HSQC-ADEQUATE: an investigation of data requirements. Magnetic resonance in chemistry : MRC 20110601
Short-term modulation at synapses between neurons in laminae II-V of the rodent spinal dorsal horn. Journal of neurophysiology 20110601
Glycine-activated chloride currents of neurons freshly isolated from the prefrontal cortex of young rats. Brain research 20110601
[Apoptosis-inducing effects of brucine on human chronic myeloid leukemia cell line K562]. Zhongguo shi yan xue ye xue za zhi 20110601
Samarium diiodide induced ketyl-(het)arene cyclisations towards novel N-heterocycles. Chemical Society reviews 20110501
Novel expression of a functional glycine receptor chloride channel that attenuates contraction in airway smooth muscle. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110501
HSQC-ADEQUATE correlation: a new paradigm for establishing a molecular skeleton. Magnetic resonance in chemistry : MRC 20110501
D-serine regulates cerebellar LTD and motor coordination through the δ2 glutamate receptor. Nature neuroscience 20110501
Fatal intoxication due to brucine. Journal of analytical toxicology 20110501
Effects of brucine combined with glycyrrhetinic acid or liquiritin on rat hepatic cytochrome P450 activities in vivo. Yao xue xue bao = Acta pharmaceutica Sinica 20110501
[Pharmacokinetics of brucine in rats after intravenous administration of liposomes containing total alkaloids from seed of Strychnos nux-vomica]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110501
Glycine enhances microglial intracellular calcium signaling. A role for sodium-coupled neutral amino acid transporters. Pflugers Archiv : European journal of physiology 20110401
[Effect of brucine on metabolism of osteoblasts and osteoclasts in multiple myeloma]. Zhongguo shi yan xue ye xue za zhi 20110401
[Effect of brucine on secretion function and proliferation capability of T lymphocytes in patients with aplastic anemia]. Zhongguo shi yan xue ye xue za zhi 20110401
[Effect of phospholipid composition on pharmaceutical properties and anti-tumor activity of stealth liposomes containing brucine]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110401
Low-power composite CPMG HSQMBC experiment for accurate measurement of long-range heteronuclear coupling constants. Magnetic resonance in chemistry : MRC 20110301
Variable angle NMR spectroscopy and its application to the measurement of residual chemical shift anisotropy. Journal of magnetic resonance (San Diego, Calif. : 1997) 20110301
Riluzole is a potent drug to protect neonatal rat hypoglossal motoneurons in vitro from excitotoxicity due to glutamate uptake block. The European journal of neuroscience 20110301
Inner and outer retinal mechanisms engaged by epiretinal stimulation in normal and rd mice. Visual neuroscience 20110301
A structural and mutagenic blueprint for molecular recognition of strychnine and d-tubocurarine by different cys-loop receptors. PLoS biology 20110301
High-throughput screening in suboptimal growth conditions identifies agonists of Giardia lamblia proliferation. Parasitology 20110201
Direct and indirect control of orexin/hypocretin neurons by glycine receptors. The Journal of physiology 20110201
High precision NOEs as a probe for low level conformers--a second conformation of strychnine. Chemical communications (Cambridge, England) 20110128
Interproton distance determinations by NOE--surprising accuracy and precision in a rigid organic molecule. Organic & biomolecular chemistry 20110107
Implications for glycine receptors and astrocytes in ethanol-induced elevation of dopamine levels in the nucleus accumbens. Addiction biology 20110101
Strychnine poisoning: gone but not forgotten. Emergency medicine journal : EMJ 20110101
CNS activities of ethanol extract of aerial parts of Hygrophila difformis in mice. Acta poloniae pharmaceutica 20110101
HPLC determination of strychnine and brucine in rat tissues and the distribution study of processed semen strychni. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110101
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IPAP-HSQMBC: measurement of long-range heteronuclear coupling constants from spin-state selective multiplets. Journal of magnetic resonance (San Diego, Calif. : 1997) 20101201
Experience-based behavioral and chemosensory changes in the generalist insect herbivore Helicoverpa armigera exposed to two deterrent plant chemicals. Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology 20101101
Glycine transporter (GlyT1) inhibitors with reduced residence time increase prepulse inhibition without inducing hyperlocomotion in DBA/2 mice. Biochemical pharmacology 20101101
Synergistic inhibition of glycinergic transmission in vitro and in vivo by flavonoids and strychnine. Toxicological sciences : an official journal of the Society of Toxicology 20101101
A short formal total synthesis of strychnine with a samarium diiodide induced cascade reaction as the key step. Angewandte Chemie (International ed. in English) 20101018
Clarke's column neurons as the focus of a corticospinal corollary circuit. Nature neuroscience 20101001
Allosteric potentiation of glycine receptor chloride currents by glutamate. Nature neuroscience 20101001
Investigation of the experimental limits of small-sample heteronuclear 2D NMR. Journal of natural products 20100924
Spectroscopic and physicochemical studies on organic crystal of brucine hydrogen maleate pentahydrate. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20100915
Transmission of phase-coupling accuracy from the auditory nerve to spherical bushy cells in the Mongolian gerbil. Hearing research 20100901
[In vitro absorption mechanism of strychnine and the transport interaction with liquiritin in Caco-2 cell monolayer model]. Yao xue xue bao = Acta pharmaceutica Sinica 20100901
Effects of sevoflurane on respiratory rhythm oscillators in the medulla oblongata. Respiratory physiology & neurobiology 20100831
The inhibitory neurotransmitter glycine modulates macrophage activity by activation of neutral amino acid transporters. Journal of neuroscience research 20100815
Presynaptic glycine receptors influence plasma membrane potential and glutamate release. Neurochemical research 20100801
Prediction of functionally selective allosteric interactions at an M3 muscarinic acetylcholine receptor mutant using Saccharomyces cerevisiae. Molecular pharmacology 20100801
Modified porphyrin-brucine conjugated to gold nanoparticles and their application in photodynamic therapy. Organic & biomolecular chemistry 20100721
Anticonvulsant, anxiolytic and sedative activities of the aqueous root extract of Securidaca longepedunculata Fresen. Journal of ethnopharmacology 20100720
Respiratory responses induced by blockades of GABA and glycine receptors within the Bötzinger complex and the pre-Bötzinger complex of the rabbit. Brain research 20100716
Active roles of electrically coupled bipolar cell network in the adult retina. The Journal of neuroscience : the official journal of the Society for Neuroscience 20100707
Neuroprotective effect of L-serine against temporary cerebral ischemia in rats. Journal of neuroscience research 20100701
Brucine N-oxide-catalyzed Morita-Baylis-Hillman reaction of vinyl ketones: a mechanistic implication of dual catalyst system with proline. Organic & biomolecular chemistry 20100628
Mechanisms of excitation of spinal networks by stimulation of the ventral roots. Annals of the New York Academy of Sciences 20100601
Deconstructing locomotor networks with experimental injury to define their membership. Annals of the New York Academy of Sciences 20100601
[The contribution of glycine and GABA(A) receptors to generation of the inhibitory postsynaptic potentials in the frog spinal cord motoneurones]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20100601
Concise total syntheses of (+/-)-strychnine and (+/-)-akuammicine. The Journal of organic chemistry 20100521
beta-Alanine elevates dopamine levels in the rat nucleus accumbens: antagonism by strychnine. Amino acids 20100401
Ayurvedic processed seeds of nux-vomica: neuropharmacological and chemical evaluation. Fitoterapia 20100401
Analgesic properties of the novel amino acid, isovaline. Anesthesia and analgesia 20100401
Presynaptic glycine receptors on hippocampal mossy fibers. Biochemical and biophysical research communications 20100319
Ammonium sulfate gradient loading of brucine into liposomes: effect of phospholipid composition on entrapment efficiency and physicochemical properties in vitro. Drug development and industrial pharmacy 20100301
Transient oxidative stress evokes early changes in the functional properties of neonatal rat hypoglossal motoneurons in vitro. The European journal of neuroscience 20100301
Death due to ingestion of nicotine-containing solution: case report and review of the literature. Forensic science international 20100225
Long-term potentiation of intrinsic excitability in trigeminal motoneurons. Brain research 20100202
Rapid and sensitive determination of strychnine and brucine in human urine by capillary electrophoresis with field-amplified sample stacking. Biomedical chromatography : BMC 20100201
The antinociceptive effect of intrathecal administration of glycine transporter-2 inhibitor ALX1393 in a rat acute pain model. Anesthesia and analgesia 20100201
Feedforward inhibition determines the angular tuning of vibrissal responses in the principal trigeminal nucleus. The Journal of neuroscience : the official journal of the Society for Neuroscience 20100120
Fictive lung ventilation in the isolated brainstem preparation of the aquatic frog, Xenopus laevis. Advances in experimental medicine and biology 20100101
Neuroprotection via strychnine-sensitive glycine receptors during post-ischemic recovery of excitatory synaptic transmission in the hippocampus. Journal of pharmacological sciences 20100101
Reciprocal regulation between taurine and glutamate response via Ca2+-dependent pathways in retinal third-order neurons. Journal of biomedical science 20100101
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[A comparative study on HPLC fingerprint of Semen Strychni and the processed]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20091201
Adiabatic z-filtered J-spectroscopy for absorptive homonuclear decoupled spectra. Journal of magnetic resonance (San Diego, Calif. : 1997) 20091101
Antagonists of ionotropic gamma-aminobutyric acid receptors impair the NiCl2-mediated stimulation of the electroretinogram b-wave amplitude from the isolated superfused vertebrate retina. Acta ophthalmologica 20091101
The association of bait formulation of strychnine with poisonings in nontarget species in Saskatchewan from 1975 to 2007. The Canadian veterinary journal = La revue veterinaire canadienne 20091101
Preparation and pharmaceutical/pharmacodynamic evaluation of topical brucine-loaded liposomal hydrogel. Journal of materials science. Materials in medicine 20091001
Synthesis of heteroaromatic tropeines and heterogeneous binding to glycine receptors. Bioorganic & medicinal chemistry 20091001
[Preparation and in vitro evaluation of brucine-loaded polylacticacid nanoparticles]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090901
Glycinergic inhibition creates a form of auditory spectral integration in nuclei of the lateral lemniscus. Journal of neurophysiology 20090801
Anticonvulsant, anxiolytic, and sedative properties of the roots of Nauclea latifolia Smith in mice. Epilepsy & behavior : E&B 20090801
Glycine inhibits the LPS-induced increase in cytosolic Ca2+ concentration and TNFalpha production in cardiomyocytes by activating a glycine receptor. Acta pharmacologica Sinica 20090801
A three-phase microfluidic chip for rapid sample clean-up of alkaloids from plant extracts. Lab on a chip 20090721
Intracerebroventricular or intrathecal injection of glycine produces analgesia in thermal nociception and chemical nociception via glycine receptors. European journal of pharmacology 20090701
Central action of Araucaria angustifolia seed lectin in mice. Epilepsy & behavior : E&B 20090701
Parallel ON and OFF cone bipolar inputs establish spatially coextensive receptive field structure of blue-yellow ganglion cells in primate retina. The Journal of neuroscience : the official journal of the Society for Neuroscience 20090701
Factual errors in Brooks and Peever's rebuttal to critiques. Sleep 20090701
Excitatory actions of ventral root stimulation during network activity generated by the disinhibited neonatal mouse spinal cord. Journal of neurophysiology 20090601
Role of glycinergic inhibition in shaping activity of saccadic burst neurons. Journal of neurophysiology 20090601
Effects of the beta-amino acid antagonist TAG on thalamocortical inhibition. Neuropharmacology 20090601
Functional role of GABAergic and glycinergic inhibition in the intermediate nucleus of the lateral lemniscus of the big brown bat. Journal of neurophysiology 20090601
Glycine receptors contribute to hypnosis induced by ethanol. Alcoholism, clinical and experimental research 20090601
A rare case of brucine poisoning complicated by rhabdomyolysis and acute renal failure. The Malaysian journal of pathology 20090601
GABAAergic and glycinergic inhibition in the phrenic nucleus organizes and couples fast oscillations in motor output. Journal of neurophysiology 20090401
Anticonvulsant properties of saponins from Ficus platyphylla stem bark. Brain research bulletin 20090330
Functional type I vanilloid receptor expression by substantia gelatinosa neurons of trigeminal subnucleus caudalis in mice. Neuroscience letters 20090320
Asymmetric control of inspiratory and expiratory phases by excitability in the respiratory network of neonatal mice in vitro. The Journal of physiology 20090315
Loss of GABAB receptors in cochlear neurons: threshold elevation suggests modulation of outer hair cell function by type II afferent fibers. Journal of the Association for Research in Otolaryngology : JARO 20090301
Role of inhibitory neurotransmission in the control of canine hypoglossal motoneuron activity in vivo. Journal of neurophysiology 20090301
Validation of anticonvulsant and sedative activity of six medicinal plants. Epilepsy & behavior : E&B 20090301
Inhibition of thalamic excitability by 4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridine-3-ol: a selective role for delta-GABA(A) receptors. The European journal of neuroscience 20090301
Cyclization of the semicarbazone template of aryl semicarbazones: synthesis and anticonvulsant activity of 4,5-diphenyl-2H-1,2,4-triazol-3(4H)-one. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20090301
Glycine inhibitory dysfunction induces a selectively dynamic, morphine-resistant, and neurokinin 1 receptor- independent mechanical allodynia. The Journal of neuroscience : the official journal of the Society for Neuroscience 20090225
Determination of strychnine and brucine in rat plasma using liquid chromatography electrospray ionization mass spectrometry. Journal of pharmaceutical and biomedical analysis 20090220
Differential effects of divalent cations on spontaneous and evoked glycine release from spinal interneurons. Journal of neurophysiology 20090201
Anti-proliferative and cytotoxic effects of Strychnos nux-vomica root extract on human multiple myeloma cell line - RPMI 8226. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090201
Behavior and cellular evidence for propofol-induced hypnosis involving brain glycine receptors. Anesthesiology 20090201
The contribution of synaptic inputs to sustained depolarizations in reticulospinal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience 20090128
Effects of activation of group III metabotropic glutamate receptors on spinal synaptic transmission in a rat model of neuropathic pain. Neuroscience 20090123
Modulation of the sympathetic response to acute hypoxia by the caudal ventrolateral medulla in rats. The Journal of physiology 20090115
Drug enhancement of memory consolidation: historical perspective and neurobiological implications. Psychopharmacology 20090101
Effect of glycine on the release of reactive oxygen species in human neutrophils. International immunopharmacology 20090101
Switching of the transmitters that mediate hindbrain correlated activity in the chick embryo. The European journal of neuroscience 20090101
The glycine transport inhibitor sarcosine is an inhibitory glycine receptor agonist. Neuropharmacology 20090101
Electrical synapses between AII amacrine cells: dynamic range and functional consequences of variation in junctional conductance. Journal of neurophysiology 20081201
Simple and rapid extraction, separation, and detection of alkaloids in beverages. Journal of separation science 20081201
Effects of extracts and neferine from the embryo of Nelumbo nucifera seeds on the central nervous system. Phytomedicine : international journal of phytotherapy and phytopharmacology 20081201
A transmembrane residue influences the interaction of propofol with the strychnine-sensitive glycine alpha1 and alpha1beta receptor. Anesthesia and analgesia 20081201
[Study on safety and pharmacodynamic action of transdermal liposomal brucine]. Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20081201
3-Nitropropionic acid depresses spinal reflexes involving GABAergic and glycinergic transmission in neonatal rat spinal cord in vitro. Life sciences 20081121
Glycine-mediated changes of onset reliability at a mammalian central synapse. Neuroscience 20081119
Functional expression of the glycine transporter 1 on bullfrog retinal cones. Neuroreport 20081119
Tonic GABAergic inhibition of sympathetic preganglionic neurons: a novel substrate for sympathetic control. The Journal of neuroscience : the official journal of the Society for Neuroscience 20081119
Simultaneous determination of five toxic alkaloids in body fluids by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20081115
Glycine input induces the synaptic facilitation in salamander rod photoreceptors. Journal of biomedical science 20081101
Neuropharmacological studies on Wedelia calendulacea Less stem extract. Phytomedicine : international journal of phytotherapy and phytopharmacology 20081101
Adventures and tribulations in the search for the mechanisms of the atonia of REM sleep. Sleep 20081101
Fast non-genomic effects of progesterone-derived neurosteroids on nociceptive thresholds and pain symptoms. Pain 20081031
Reconfiguration of respiratory-related population activity in a rostrally tilted transversal slice preparation following blockade of inhibitory neurotransmission in neonatal rats. Pflugers Archiv : European journal of physiology 20081001
Chloride-dependent acute excitotoxicity in adult rat retinal ganglion cells. Neuropharmacology 20081001
Depression of spinal network activity by thiopental: shift from phasic to tonic GABA(A) receptor-mediated inhibition. Neuropharmacology 20081001
The glycine transporter GlyT2 controls the dynamics of synaptic vesicle refilling in inhibitory spinal cord neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience 20080924
Retinal ON bipolar cells express a new PCP2 splice variant that accelerates the light response. The Journal of neuroscience : the official journal of the Society for Neuroscience 20080903
Group I mGluRs increase locomotor network excitability in Xenopus tadpoles via presynaptic inhibition of glycinergic neurotransmission. The European journal of neuroscience 20080901
[Pharmaceutical characteristics of brucine stealth liposomes]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080901
[Influencing factors in preparation of brucine liposomes by ammonium sulfate transmembrane gradients]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20080901
Phythochemical screening and anticonvulsant activity of Cymbopogon winterianus Jowitt (Poaceae) leaf essential oil in rodents. Phytomedicine : international journal of phytotherapy and phytopharmacology 20080801
Synaptic regulation of the light-dependent oscillatory currents in starburst amacrine cells of the mouse retina. Journal of neurophysiology 20080801
Cellular and synaptic actions of acetylcholine in the lamprey spinal cord. Journal of neurophysiology 20080801
Glycine receptors mediate excitation of subplate neurons in neonatal rat cerebral cortex. Journal of neurophysiology 20080801
Complex temporal response patterns with a simple retinal circuit. Journal of neurophysiology 20080801
Zinc modulation of glycine receptors in acutely isolated rat CA3 neurons. Life sciences 20080801
Frequency-dependent glycinergic inhibition modulates plasticity in hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience 20080716
Interaural time difference processing in the mammalian medial superior olive: the role of glycinergic inhibition. The Journal of neuroscience : the official journal of the Society for Neuroscience 20080702
Development of presynaptic inhibition onto retinal bipolar cell axon terminals is subclass-specific. Journal of neurophysiology 20080701
Early postnatal development of reciprocal Ia inhibition in the murine spinal cord. Journal of neurophysiology 20080701
Pathway-dependent modulation by P2-purinoceptors in the mouse retina. The European journal of neuroscience 20080701
New technique for drug application to the spinal cord of walking mice. Journal of neuroscience methods 20080615
The CLIP/CLAP-HSQC: pure absorptive spectra for the measurement of one-bond couplings. Journal of magnetic resonance (San Diego, Calif. : 1997) 20080601
Induction of G2/M arrest and apoptosis by water extract of Strychni Semen in human gastric carcinoma AGS cells. Phytotherapy research : PTR 20080601
[Research on pharmacology, toxicology and safety of Semen Strychni: review and prospect]. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20080601
Spatiotemporal organization of frog respiratory neurons visualized on the ventral medullary surface. Respiratory physiology & neurobiology 20080531
Synthesis and preliminary evaluation of some substituted coumarins as anticonvulsant agents. Bioorganic & medicinal chemistry 20080515
Differential modulation of neural network and pacemaker activity underlying eupnea and sigh-breathing activities. Journal of neurophysiology 20080501
Regulation of neurosteroid allopregnanolone biosynthesis in the rat spinal cord by glycine and the alkaloidal analogs strychnine and gelsemine. Neuroscience 20080422
Glycinergic and GABA(A)-mediated inhibition of somatic motoneurons does not mediate rapid eye movement sleep motor atonia. The Journal of neuroscience : the official journal of the Society for Neuroscience 20080402
Glycinergic synaptic currents in the deep cerebellar nuclei. Neuropharmacology 20080401
Differential inhibitory control of semicircular canal nerve afferent-evoked inputs in second-order vestibular neurons by glycinergic and GABAergic circuits. Journal of neurophysiology 20080401
Sophisticated temporal pattern recognition in retinal ganglion cells. Journal of neurophysiology 20080401
Local oscillations of spiking activity in organotypic spinal cord slice cultures. The European journal of neuroscience 20080401
Single-photon absorptions evoke synaptic depression in the retina to extend the operational range of rod vision. Neuron 20080327
Supramolecular tilt chirality in crystals of steroids and alkaloids. Chirality 20080301
Blunted response to low oxygen of rat respiratory network after perinatal ethanol exposure: involvement of inhibitory control. The Journal of physiology 20080301
Local circuit connections between hamster laminae III and IV dorsal horn neurons. Journal of neurophysiology 20080301
Synaptic responses of neurons controlling the parotid and von Ebner salivary glands in rats to stimulation of the solitary nucleus and tract. Journal of neurophysiology 20080301
Influence of inhibitory inputs on rate and timing of responses in the anteroventral cochlear nucleus. Journal of neurophysiology 20080301
Phospholipase A2 activation enhances inhibitory synaptic transmission in rat substantia gelatinosa neurons. Journal of neurophysiology 20080301
Local inhibition shapes duration tuning in the inferior colliculus of guinea pigs. Hearing research 20080301
A simple method to identify the unprocessed Strychnos seeds used in herbal medicinal products. Planta medica 20080301
[Study on transdermal absorption characteristics of brucine in vitro]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20080301
Dantrolene antagonizes the glycineB site of the NMDA receptor. Neuroscience letters 20080220
Synthesis of (nor)tropeine (di)esters and allosteric modulation of glycine receptor binding. Bioorganic & medicinal chemistry 20080215
Taurine activates glycine and gamma-aminobutyric acid A receptors in rat substantia gelatinosa neurons. Neuroreport 20080212
Microchip micellar electrokinetic chromatography separation of alkaloids with UV-absorbance spectral detection. Electrophoresis 20080201
Strychnine--a killer from the past. The Israel Medical Association journal : IMAJ 20080201
Hyperekplexia mutation R271L of alpha1 glycine receptors potentiates allosteric interactions of nortropeines, propofol and glycine with [3H]strychnine binding. Neurochemistry international 20080101
Glycinergic input of small-field amacrine cells in the retinas of wildtype and glycine receptor deficient mice. Molecular and cellular neurosciences 20080101
Locomotor pattern in the adult zebrafish spinal cord in vitro. Journal of neurophysiology 20080101
Spectral editing of organic mixtures into pure components using NMR spectroscopy and ultraviscous solvents. Analytical chemistry 20080101
Strychnine-sensitive glycine receptors mediate the analgesic but not the hypnotic effects of emulsified volatile anaesthetics. Pharmacology 20080101
[On the glycinergic component of the mechanisms of medial vestibular nucleus neurons functioning]. Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine 20080101
Final report of the safety assessment of Alcohol Denat., including SD Alcohol 3-A, SD Alcohol 30, SD Alcohol 39, SD Alcohol 39-B, SD Alcohol 39-C, SD Alcohol 40, SD Alcohol 40-B, and SD Alcohol 40-C, and the denaturants, Quassin, Brucine Sulfate/Brucine, and Denatonium Benzoate. International journal of toxicology 20080101
Rhythm generation by the pre-Bötzinger complex in medullary slice and island preparations: effects of adenosine A(1) receptor activation. BMC neuroscience 20080101
Conformational variability of the glycine receptor M2 domain in response to activation by different agonists. The Journal of biological chemistry 20071207
Zinc enhances the inhibitory effects of strychnine-sensitive glycine receptors in mouse hippocampal neurons. Journal of neurophysiology 20071201
Inhibitory feedback shapes bipolar cell responses in the rabbit retina. Journal of neurophysiology 20071201
Synthesis and anticonvulsant evaluation of 4-(4-alkoxylphenyl)-3-ethyl-4H-1,2,4-triazoles as open-chain analogues of 7-alkoxyl-4,5-dihydro[1,2,4]triazolo[4,3-a]quinolines. Bioorganic & medicinal chemistry 20071101
Preparation of liposomal brucine and its pharmaceutical/pharmacodynamic characterization. Acta pharmacologica Sinica 20071101
Differential contribution of GABAergic and glycinergic components to inhibitory synaptic transmission in lamina II and laminae III-IV of the young rat spinal cord. The European journal of neuroscience 20071101
The effect of ivermectin on convulsions in rats produced by lidocaine and strychnine. Veterinary research communications 20071001
[Simultaneous screening for 22 poisonous alkaloids in blood by liquid chromatography-tandem mass spectrometry with multiple-reaction monitoring]. Fa yi xue za zhi 20071001
GABAA and glycine receptor-mediated transmission in rat lamina II neurones: relevance to the analgesic actions of neuroactive steroids. The Journal of physiology 20070915
The cytotoxicity induced by brucine from the seed of Strychnos nux-vomica proceeds via apoptosis and is mediated by cyclooxygenase 2 and caspase 3 in SMMC 7221 cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20070901
Using unsymmetrical indirect covariance processing to calculate GHSQC-COSY spectra. Journal of natural products 20070901
Corticospinal control of antagonistic muscles in the cat. The European journal of neuroscience 20070901
Rethinking tuning: in vivo whole-cell recordings of the inferior colliculus in awake bats. The Journal of neuroscience : the official journal of the Society for Neuroscience 20070829
The effect of zinc on glycinergic inhibitory postsynaptic currents in rat spinal dorsal horn neurons. Brain research 20070803
Prenatal nicotine exposure alters glycinergic and GABAergic control of respiratory frequency in the neonatal rat brainstem-spinal cord preparation. Respiratory physiology & neurobiology 20070801
Pharmacological characterization of glycine-activated currents in HEK 293 cells expressing N-methyl-D-aspartate NR1 and NR3 subunits. The Journal of pharmacology and experimental therapeutics 20070801
Are pacemaker properties required for respiratory rhythm generation in adult turtle brain stems in vitro? American journal of physiology. Regulatory, integrative and comparative physiology 20070801
Anesthetic-like modulation of a gamma-aminobutyric acid type A, strychnine-sensitive glycine, and N-methyl-d-aspartate receptors by coreleased neurotransmitters. Anesthesia and analgesia 20070801
Pseudopolymorphism in brucine: brucine-water (1/2), the third crystal hydrate of brucine. Acta crystallographica. Section C, Crystal structure communications 20070801
Broad tuning of the human bitter taste receptor hTAS2R46 to various sesquiterpene lactones, clerodane and labdane diterpenoids, strychnine, and denatonium. Journal of agricultural and food chemistry 20070725
Corelease of GABA/glycine in lamina-X of the spinal cord of neonatal rats. Neuroreport 20070702
Differential modulation by tetraethylammonium of the processes underlying network bursting in the neonatal rat spinal cord in vitro. Neuroscience 20070608
P.E.HSQC: a simple experiment for simultaneous and sign-sensitive measurement of (1JCH+DCH) and (2JHH+DHH) couplings. Journal of magnetic resonance (San Diego, Calif. : 1997) 20070601
Glycine-induced long-term synaptic potentiation is mediated by the glycine transporter GLYT1. Neuropharmacology 20070601
Glycine as a potent anti-angiogenic nutrient for tumor growth. Journal of gastroenterology and hepatology 20070601
Application of high performance capillary electrophoresis on toxic alkaloids analysis. Journal of separation science 20070601
Respiratory activity in brainstem of fetal mice lacking glutamate decarboxylase 65/67 and vesicular GABA transporter. Neuroscience 20070525
Spontaneous IPSCs and glycine receptors with slow kinetics in wide-field amacrine cells in the mature rat retina. The Journal of physiology 20070515
Excitatory interneurons dominate sensory processing in the spinal substantia gelatinosa of rat. The Journal of physiology 20070515
Novel 3-O-glycosyl-3-demethylthiocolchicines as ligands for glycine and gamma-aminobutyric acid receptors. Journal of medicinal chemistry 20070503
Taurine in the anterior cingulate cortex diminishes neuropathic nociception: a possible interaction with the glycine(A) receptor. European journal of pain (London, England) 20070501
A novel effect of cochlear efferents: in vivo response enhancement does not require alpha9 cholinergic receptors. Journal of neurophysiology 20070501
High potassium-induced facilitation of glycine release from presynaptic terminals on mechanically dissociated rat spinal dorsal horn neurons in the absence of extracellular calcium. Neuroscience 20070425
Glycine receptors are functionally expressed on bullfrog retinal cone photoreceptors. Neuroscience 20070425
[Study on the interaction between brucine and bovine serum albumin]. Guang pu xue yu guang pu fen xi = Guang pu 20070401
Anticonvulsant activity of hydroalcoholic extracts from Erythrina velutina and Erythrina mulungu. Journal of ethnopharmacology 20070321
Strychnine and taurine modulation of amygdala-associated anxiety-like behavior is 'state' dependent. Behavioural brain research 20070312
Hollow fiber-based liquid-phase microextraction combined with on-line sweeping for trace analysis of Strychnos alkaloids in urine by micellar electrokinetic chromatography. Journal of chromatography. A 20070302
Reactive oxygen species mediate central cardiorespiratory network responses to acute intermittent hypoxia. Journal of neurophysiology 20070301
Anti-homeostatic synaptic plasticity of glycine receptor function after chronic strychnine in developing cultured mouse spinal neurons. Journal of neurochemistry 20070301
Three types of inhibitory miniature potentials in frog spinal cord motoneurons: possible GABA and glycine cotransmission. Neuroscience and behavioral physiology 20070301
Strychnine-sensitive glycine receptors mediate analgesia induced by emulsified inhalation anaesthetics in thermal nociception but not in chemical nociception. Basic & clinical pharmacology & toxicology 20070301
Facilitation of spontaneous glycine release by anoxia potentiates NMDA receptor current in the hypoglossal motor neurons of the rat. The European journal of neuroscience 20070301
Glycinergic inputs cause the pause of pontine omnipause neurons during saccades. Neuroscience letters 20070208
GABA, not glycine, mediates inhibition of latent respiratory motor pathways after spinal cord injury. Experimental neurology 20070201
Distinct roles for glycine and GABA in shaping the response properties of neurons in the superior paraolivary nucleus of the rat. Journal of neurophysiology 20070201
Balanced inhibition and excitation drive spike activity in spinal half-centers. Science (New York, N.Y.) 20070119
Total synthesis of (+/-)-strychnine via a [4 + 2]-cycloaddition/rearrangement cascade. Organic letters 20070118
Characterization and restoration of altered inhibitory and excitatory control of micturition reflex in experimental autoimmune encephalomyelitis in rats. The Journal of physiology 20070115
L-type calcium channels and NMDA receptors: a determinant duo for short-term nociceptive plasticity. The European journal of neuroscience 20070101
Early electrophysiological abnormalities in lumbar motoneurons in a transgenic mouse model of amyotrophic lateral sclerosis. The European journal of neuroscience 20070101
Strychnine-sensitive glycine receptors mediate the analgesic but not hypnotic effects of emulsified volatile anesthetics. Pharmacology 20070101
Decline in pesticide poisonings in the United States from 1995 to 2004. Clinical toxicology (Philadelphia, Pa.) 20070101
Differential distribution of glycine transporters in Müller cells and neurons in amphibian retinas. Visual neuroscience 20070101
Taurine induces anti-anxiety by activating strychnine-sensitive glycine receptor in vivo. Annals of nutrition & metabolism 20070101
The activation of nicotinic acetylcholine receptors enhances the inhibitory synaptic transmission in the deep dorsal horn neurons of the adult rat spinal cord. Molecular pain 20070101
Strychnine, but not PMBA, inhibits neuronal nicotinic acetylcholine receptors expressed by rabbit retinal ganglion cells. Visual neuroscience 20070101
Development and validation of a TLC-densitometric method for the simultaneous quantitation of strychnine and brucine from Strychnos spp. and its formulations. Journal of chromatographic science 20070101
Recent studies on the synthesis of strychnine. The Alkaloids. Chemistry and biology 20070101
Quantitative LC-MS determination of strychnine in urine after ingestion of a Strychnos nux-vomica preparation and its consequences in doping control. Forensic science international 20061220
Histaminergic and glycinergic modulation of GABA release in the vestibular nuclei of normal and labyrinthectomised rats. The Journal of physiology 20061215
In vitro galantamine-memantine co-application: mechanism of beneficial action. Neuropharmacology 20061201
Hydrophobic 'lock and key' recognition of N-4-nitrobenzoylamino acid by strychnine. Acta crystallographica. Section B, Structural science 20061201
[Advances in our knowledge of the causation and pathophysiology of reflex epilepsies]. Revista de neurologia 20061201
Preliminary pharmacological screening of Bixa orellana L. leaves. Journal of ethnopharmacology 20061124
Vesicular glutamate transporter 2 is required for central respiratory rhythm generation but not for locomotor central pattern generation. The Journal of neuroscience : the official journal of the Society for Neuroscience 20061122
Functional characterization of the epidermal cholinergic system in vitro. The Journal of investigative dermatology 20061101
HPLC-UV method for nicotine, strychnine, and aconitine in dairy products. Journal of agricultural and food chemistry 20061004
Chloride homeostasis differentially affects GABA(A) receptor- and glycine receptor-mediated effects on spontaneous circuit activity in hippocampal cell culture. Neuroscience letters 20061002
3-demethoxy-3-glycosylaminothiocolchicines: Synthesis of a new class of putative muscle relaxant compounds. Journal of medicinal chemistry 20060907
Endogenous monoamine receptor activation is essential for enabling persistent sodium currents and repetitive firing in rat spinal motoneurons. Journal of neurophysiology 20060901
Selective J-resolved spectra: a double pulsed field gradient spin-echo approach. Journal of magnetic resonance (San Diego, Calif. : 1997) 20060901
Diffusion coefficient distribution from NMR-DOSY experiments using Hopfield neural network. Journal of magnetic resonance (San Diego, Calif. : 1997) 20060901
Intentional strychnine use and overdose--an entity of the past? Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine 20060901
Maturation of firing pattern in chick vestibular nucleus neurons. Neuroscience 20060825
Absence of GABA type A signaling in adult medial habenular neurons. Neuroscience 20060811
Detection of strychnine by gas chromatography-mass spectrometry in the carcase of a Bonelli's eagle (Hieraaetus fasciatus). The Veterinary record 20060805
Fast cholinergic efferent inhibition in guinea pig outer hair cells. Brain research 20060802
Medullary lateral tegmental field neurons influence the timing and pattern of phrenic nerve activity in cats. Journal of applied physiology (Bethesda, Md. : 1985) 20060801
Blockade of inhibitory neurotransmission evoked seizure-like firing of cardiac parasympathetic neurons in brainstem slices of newborn rats: Implications for sudden deaths in patients of epilepsy. Epilepsy research 20060801
Hydrogen sulfide mediates hypoxia-induced relaxation of trout urinary bladder smooth muscle. The Journal of experimental biology 20060801
Synaptic inputs to retinal ganglion cells that set the circadian clock. The European journal of neuroscience 20060801
Toward the complete prediction of the 1H and 13C NMR spectra of complex organic molecules by DFT methods: application to natural substances. Chemistry (Weinheim an der Bergstrasse, Germany) 20060717
Modeling Starburst cells' GABA(B) receptors and their putative role in motion sensitivity. Biophysical journal 20060715
Purinergic P2 receptors modulate excitability but do not mediate pH sensitivity of RTN respiratory chemoreceptors. The Journal of neuroscience : the official journal of the Society for Neuroscience 20060705
Inhibitory synaptic transmission governs inspiratory motoneuron synchronization. Journal of neurophysiology 20060701
Calcium-regulated potassium currents secure respiratory rhythm generation after loss of glycinergic inhibition. The European journal of neuroscience 20060701
[Interaction between strychnine and bovine serum albumin]. Yao xue xue bao = Acta pharmaceutica Sinica 20060701
The anti-tumor effects of alkaloids from the seeds of Strychnos nux-vomica on HepG2 cells and its possible mechanism. Journal of ethnopharmacology 20060630
Pharmacological characterisation of strychnine and brucine analogues at glycine and alpha7 nicotinic acetylcholine receptors. European journal of pharmacology 20060606
Bilirubin potentiates inhibitory synaptic transmission in lateral superior olive neurons of the rat. Neuroscience research 20060601
Brucine salts of L-alpha-hydroxy acids: brucinium hydrogen (S)-malate pentahydrate and anhydrous brucinium hydrogen (2R,3R)-tartrate at 130 K. Acta crystallographica. Section C, Crystal structure communications 20060601
Taurine elevates dopamine levels in the rat nucleus accumbens; antagonism by strychnine. The European journal of neuroscience 20060601
Synthesis and anticonvulsant activities of N-Cbz-alpha-aminoglutarimidooxy carboxylate derivatives. Archives of pharmacal research 20060601
GABAergic and glycinergic inhibitory mechanisms in the lamprey respiratory control. Brain research 20060523
Switching-on and -off of bistable spontaneous discharges in rat spinal deep dorsal horn neurons. Neuroscience letters 20060508
Separation and determination of strychnine and brucine in Strychnos nux-vomica L. and its preparation by nonaqueous capillary electrophoresis. Journal of pharmaceutical and biomedical analysis 20060503
Distinct physiological mechanisms underlie altered glycinergic synaptic transmission in the murine mutants spastic, spasmodic, and oscillator. The Journal of neuroscience : the official journal of the Society for Neuroscience 20060503
The apoptotic effect of brucine from the seed of Strychnos nux-vomica on human hepatoma cells is mediated via Bcl-2 and Ca2+ involved mitochondrial pathway. Toxicological sciences : an official journal of the Society of Toxicology 20060501
Roles of inhibition in complex auditory responses in the inferior colliculus: inhibited combination-sensitive neurons. Journal of neurophysiology 20060401
Glycine-gated chloride channels depress synaptic transmission in rat hippocampus. Journal of neurophysiology 20060401
Can one gain spectral information plus time by 3D HMBC via back-projection? Magnetic resonance in chemistry : MRC 20060401
Effect of prevention of lung inflation on metamorphosis and respiration in the developing bullfrog tadpole, Rana catesbeiana. Journal of experimental zoology. Part A, Comparative experimental biology 20060401
Glycine receptors in a population of adult mammalian cones. The Journal of physiology 20060301
[Studies on quality control methods of nuxvomica]. Guang pu xue yu guang pu fen xi = Guang pu 20060201
Measurement of electrical activity of long-term mammalian neuronal networks on semiconductor neurosensor chips and comparison with conventional microelectrode arrays. Biosensors & bioelectronics 20060115
Study of the interaction of antiplasmodial strychnine derivatives with the glycine receptor. European journal of pharmacology 20060113
Incorporation of selective population transfer and homo-spin decoupling into selective one-dimensional experiments. Magnetic resonance in chemistry : MRC 20060101
Rapid separation of strychnine and brucine on a dynamically modified poly(dimethylsiloxane) microchip followed by electrochemical detection. Analytical and bioanalytical chemistry 20060101
Zinc modulates primary afferent fiber-evoked responses of ventral roots in neonatal rat spinal cord in vitro. Neuroscience 20060101
Characterization of the glycinergic input to bipolar cells of the mouse retina. The European journal of neuroscience 20060101
Analysis of strychnos alkaloids using electrospray ionization Fourier transform ion cyclotron resonance multi-stage tandem mass spectrometry. Rapid communications in mass spectrometry : RCM 20060101
[Three types of miniature inhibitory potentiaes in the frog spinal cord motoneurons: the possibility of GABA and glycine co-release]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20060101
[Effect of antagonists of inhibiting amino acids on motoneuron postsynaptic potentials in Rana ridibunda]. Zhurnal evoliutsionnoi biokhimii i fiziologii 20060101
Relationship between tonic inhibitory currents and phasic inhibitory activity in the spinal cord lamina II region of adult mice. Molecular pain 20060101
Determinants of positive cooperativity between strychnine-like allosteric modulators and N-methylscopolamine at muscarinic receptors. Journal of molecular neuroscience : MN 20060101
The neurotransmitters glycine and GABA stimulate glucagon-like peptide-1 release from the GLUTag cell line. The Journal of physiology 20051215
Suppression of ih contributes to propofol-induced inhibition of mouse cortical pyramidal neurons. Journal of neurophysiology 20051201
Differing roles of inhibition in hierarchical processing of species-specific calls in auditory brainstem nuclei. Journal of neurophysiology 20051201
Last orders, gents.. British journal of sports medicine 20051201
Noradrenergic, serotonergic and GABAergic antagonists injected together into the XII nucleus abolish the REM sleep-like depression of hypoglossal motoneuronal activity. Journal of sleep research 20051201
Physiological characterization, localization and synaptic inputs of bursting and nonbursting neurons in the trigeminal principal sensory nucleus of the rat. The European journal of neuroscience 20051201
Glycine modulates the center response of ON type rod-dominant bipolar cells in carp retina. Brain research bulletin 20051130
Molecular basis for zinc potentiation at strychnine-sensitive glycine receptors. The Journal of biological chemistry 20051111
Physicochemical characterization of the Strychnos alkaloids by capillary zone electrophoresis. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20051101
Metachronal propagation of motoneurone burst activation in isolated spinal cord of newborn rat. The Journal of physiology 20051015
Functional characterisation of human glycine receptors in a fluorescence-based high throughput screening assay. European journal of pharmacology 20051003
The estrogen receptor modulator tamoxifen enhances spontaneous glycinergic synaptic inhibition of hypoglossal motoneurons. Endocrinology 20051001
A two-stage approach to automatic determination of 1H NMR coupling constants. Magnetic resonance in chemistry : MRC 20051001
Gompertz kinetics model of fast chemical neurotransmission currents. Synapse (New York, N.Y.) 20051001
Long-range oscillatory Ca2+ waves in rat spinal dorsal horn. The European journal of neuroscience 20051001
Long-term intracellular recordings of respiratory neuronal activities in situ during eupnea, gasping and blockade of synaptic transmission. Journal of neuroscience methods 20050930
Rapid vesicular release, quantal variability, and spillover contribute to the precision and reliability of transmission at a glomerular synapse. The Journal of neuroscience : the official journal of the Society for Neuroscience 20050907
Spatiotemporal patterns of dorsal root-evoked network activity in the neonatal rat spinal cord: optical and intracellular recordings. Journal of neurophysiology 20050901
Glycinergic inhibition in thalamus revealed by synaptic receptor blockade. Neuropharmacology 20050901
Monoaminergic establishment of rostrocaudal gradients of rhythmicity in the neonatal mouse spinal cord. Journal of neurophysiology 20050801
Optical imaging of large-scale correlated wave activity in the developing rat CNS. Journal of neurophysiology 20050801
Presynaptic angiotensin II AT1 receptors enhance inhibitory and excitatory synaptic neurotransmission to motoneurons and other ventral horn neurons in neonatal rat spinal cord. Journal of neurophysiology 20050801
Target-dependent use of co-released inhibitory transmitters at central synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience 20050713
Glycine binding site of the synaptic NMDA receptor in subpostremal NTS neurons. Journal of neurophysiology 20050701
Cardiovascular response to a group III mGluR agonist in NTS requires NMDA receptors. American journal of physiology. Regulatory, integrative and comparative physiology 20050701
CNS depressant activity of Lecaniodiscus cupanioides. Fitoterapia 20050701
Light signaling in scotopic conditions in the rabbit, mouse and rat retina: a physiological and anatomical study. Journal of neurophysiology 20050601
Roles of inhibition in creating complex auditory responses in the inferior colliculus: facilitated combination-sensitive neurons. Journal of neurophysiology 20050601
Taurine activates excitatory non-synaptic glycine receptors on dopamine neurones in ventral tegmental area of young rats. The Journal of physiology 20050601
Congenital bilateral vocal cord paralysis and the role of glycine. The Annals of otology, rhinology, and laryngology 20050601
Heteronuclear two-bond correlation: suppressing heteronuclear three-bond or higher NMR correlations while enhancing two-bond correlations even for vanishing 2J(CH). Journal of the American Chemical Society 20050504
Development of an inhibitory interneuronal circuit in the embryonic spinal cord. Journal of neurophysiology 20050501
Synaptic physiology in the cochlear nucleus angularis of the chick. Journal of neurophysiology 20050501
Asparagine, valine, and threonine in the third extracellular loop of muscarinic receptor have essential roles in the positive cooperativity of strychnine-like allosteric modulators. The Journal of pharmacology and experimental therapeutics 20050501
[Strychnine nitrate' effect on intracellular potentials of Mauthner cell evoked by skin stimulation in the crucian carps]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20050501
Induction of delta-opioid receptor function in the midbrain after chronic morphine treatment. The Journal of neuroscience : the official journal of the Society for Neuroscience 20050323
Inhibitory influence of ginsenoside Rb(3) on activation of strychnine-sensitive glycine receptors in hippocampal neurons of rat. Brain research 20050310
The beta subunit determines the ligand binding properties of synaptic glycine receptors. Neuron 20050303
Insulin-like growth factor-1 inhibits adult supraoptic neurons via complementary modulation of mechanoreceptors and glycine receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience 20050302
Glycine-induced neurotoxicity in organotypic hippocampal slice cultures. Experimental brain research 20050301
Simultaneous contribution of two rod pathways to AII amacrine and cone bipolar cell light responses. Journal of neurophysiology 20050301
Inhibitory synapses in the developing auditory system are glutamatergic. Nature neuroscience 20050301
Characterization of strychnine-sensitive glycine receptor in the intact frog retina: modulation by protein kinases. Neurochemical research 20050301
Application of solid phase microextraction to the determination of strychnine in blood. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050225
Differential postnatal maturation of GABAA, glycine receptor, and mixed synaptic currents in Renshaw cells and ventral spinal interneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience 20050223
GABAergic neurons in the central region of the spinal cord: a novel substrate for sympathetic inhibition. The Journal of neuroscience : the official journal of the Society for Neuroscience 20050202
Charge density of (-)-strychnine from 100 to 15 K, a comparison of four data sets. Acta crystallographica. Section B, Structural science 20050201
[Concentration and determination of strychnine alkaloid in biological fluids]. Fa yi xue za zhi 20050201
Retinal bipolar cell input mechanisms in giant danio. I. Electroretinographic analysis. Journal of neurophysiology 20050101
[Development of new synthetic method using organometallic complexes and an application toward natural product synthesis]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20050101
Accumbal strychnine-sensitive glycine receptors: an access point for ethanol to the brain reward system. Alcoholism, clinical and experimental research 20050101
Distinct roles of glycinergic and GABAergic inhibition in coordinating locomotor-like rhythms in the neonatal mouse spinal cord. Neuroscience 20050101
Rectal distention inhibits the spinal micturition reflex via glycinergic or GABAergic mechanisms in rats with spinal cord injury. Urologia internationalis 20050101
Hypoxia recruits a respiratory-related excitatory pathway to brainstem premotor cardiac vagal neurons in animals exposed to prenatal nicotine. Neuroscience 20050101
Determination of strychnine in human blood using solid-phase extraction and GC-EI-MS. Journal of analytical toxicology 20050101
Structural difference between heteromeric somatic and homomeric axonal glycine receptors in the hypothalamo-neurohypophysial system. Neuroscience 20050101
Strychnine induces embryotoxicity in rat neurulation. Neurotoxicology and teratology 20050101
Gycine and GABA interact to regulate the nitric oxide/cGMP signaling pathway in the turtle retina. Visual neuroscience 20050101
Synthesis of tropeines and allosteric modulation of ionotropic glycine receptors. Journal of medicinal chemistry 20041202
Resolution of (+/-)-ibuprofen using (-)-brucine as a chiral selector by thin layer chromatography. Biomedical chromatography : BMC 20041201
Two antagonistic gustatory receptor neurons responding to sweet-salty and bitter taste in Drosophila. Journal of neurobiology 20041201
A new selective population transfer experiment using a double pulsed field gradient spin-echo. Magnetic resonance in chemistry : MRC 20041201
Direct determination of brucine by square wave voltammetry on 4-amino-2-mercaptopyrimidine self-assembled monolayer gold electrode. Bioelectrochemistry (Amsterdam, Netherlands) 20041201
Pentobarbital induces thalamic oscillations in brain slices, modulated by GABA and glycine receptors. Neuropharmacology 20041201
Development of a high performance liquid chromatography/mass spectroscopy method for the determination of strychnine concentrations in insects used to assess potential risks to insectivores. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041125
Laminar distribution of GABAA- and glycine-receptor mediated tonic inhibition in the dorsal horn of the rat lumbar spinal cord: effects of picrotoxin and strychnine on expression of Fos-like immunoreactivity. Pain 20041101
Propofol and sevoflurane depress spinal neurons in vitro via different molecular targets. Anesthesiology 20041101
Putative NMDA receptors in Hydra: a biochemical and functional study. The European journal of neuroscience 20041101
Interneurone bursts are spontaneously associated with muscle contractions only during early phases of mouse spinal network development: a study in organotypic cultures. The European journal of neuroscience 20041101
Simultaneous assignment of all diastereotopic protons in strychnine using RDCs: PELG as alignment medium for organic molecules. The Journal of organic chemistry 20041029
[Strychnine poisoning]. Deutsche medizinische Wochenschrift (1946) 20041015
Effect of bis(acetato)tetrakis(imidazole) copper(II) in delaying the onset and reducing the mortality rate of strychnine- and thiosemicarbazide- induced convulsions. Biological trace element research 20041001
Taurine activates strychnine-sensitive glycine receptors in neurons of the rat inferior colliculus. Brain research 20040924
Chronic ethanol induces synaptic but not extrasynaptic targeting of NMDA receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience 20040908
Rabies diagnosis in the presence of strychnine and carbamate. The Veterinary record 20040904
Differential agonist sensitivity of glycine receptor alpha2 subunit splice variants. British journal of pharmacology 20040901
High-resolution synchrotron data collection for charge-density work at 100 and 20 K. Acta crystallographica. Section A, Foundations of crystallography 20040901
Total synthesis of (-)-strychnine. Journal of the American Chemical Society 20040825
Fluorescent pirenzepine derivatives as potential bitopic ligands of the human M1 muscarinic receptor. Journal of medicinal chemistry 20040812
Developmental shift in bidirectional functions of taurine-sensitive chloride channels during cortical circuit formation in postnatal mouse brain. Journal of neurobiology 20040801
Analysis of strychnine from detoxified Strychnos nux-vomica [corrected] seeds using liquid chromatography-electrospray mass spectrometry. Journal of ethnopharmacology 20040701
Cell-specific, spike timing-dependent plasticities in the dorsal cochlear nucleus. Nature neuroscience 20040701
Probing the pharmacophore for allosteric ligands of muscarinic M2 receptors: SAR and QSAR studies in a series of bisquaternary salts of caracurine V and related ring systems. Journal of medicinal chemistry 20040701
Transverse dephasing optimised NMR spectroscopy in solids: natural-abundance 13C correlation spectra. Chemphyschem : a European journal of chemical physics and physical chemistry 20040621
A novel hyperekplexia-causing mutation in the pre-transmembrane segment 1 of the human glycine receptor alpha1 subunit reduces membrane expression and impairs gating by agonists. The Journal of biological chemistry 20040611
Anticonvulsant activity of Mimosa pudica decoction. Fitoterapia 20040601
Intracuneate mechanisms underlying primary afferent cutaneous processing in anaesthetized cats. The European journal of neuroscience 20040601
Allosteric modulation of glycine receptors is more efficacious for partial rather than full agonists. Neurochemistry international 20040601
Pacemaker activity in hydra is modulated by glycine receptor ligands. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20040601
Fentanyl inhibits GABAergic neurotransmission to cardiac vagal neurons in the nucleus ambiguus. Brain research 20040508
Afferent modulation of neonatal rat respiratory rhythm in vitro: cellular and synaptic mechanisms. The Journal of physiology 20040501
Liquid chromatography/photodiode array detection for determination of strychnine in blood: a fatal case report. Forensic science international 20040420
The effects of propofol on hypothalamic paraventricular nucleus neurons in the rat. Anesthesia and analgesia 20040401
Inhibitory effects of the essential oil from SuHeXiang Wan on the central nervous system after inhalation. Biological & pharmaceutical bulletin 20040401
A case of acute strychnine poisoning. Veterinary and human toxicology 20040401
Sensitivity of the neuronal network biosensor to environmental threats. Journal of toxicology and environmental health. Part A 20040401
A role for ligand-gated ion channels in rod photoreceptor development. Neuron 20040325
Striatal PSA-NCAM(+) precursor cells from the newborn rat express functional glycine receptors. Neuroreport 20040322
Rectal distention inhibits bladder activity via glycinergic and GABAergic mechanisms in rats. The Journal of urology 20040301
On-chip potential gradient detection with a portable capillary electrophoresis system. Electrophoresis 20040301
Strychnine overdose following ingestion of gopher bait. Journal of analytical toxicology 20040301
Analysis of strychnine and brucine in postmortem specimens by RP-HPLC: a case report of fatal intoxication. Journal of analytical toxicology 20040301
Measuring synchronization in neuronal networks for biosensor applications. Biosensors & bioelectronics 20040215
Inhibition of hippocampal LTP by ginkgolide B is mediated by its blocking action on PAF rather than glycine receptors. Neurochemistry international 20040201
Selective antagonism of rat inhibitory glycine receptor subunits. The Journal of physiology 20040201
Contributions of NMDA receptors to network recruitment and rhythm generation in spinal cord cultures. The European journal of neuroscience 20040201
Conserved high affinity ligand binding and membrane association in the native and refolded extracellular domain of the human glycine receptor alpha1-subunit. The Journal of biological chemistry 20040116
Molecular determinants of proton modulation of glycine receptors. The Journal of biological chemistry 20040109
Development of a method for the measurement of long-range 13C-1H coupling constants from HMBC spectra. Journal of magnetic resonance (San Diego, Calif. : 1997) 20040101
Potentiation of panic-like behaviors of the rat by subconvulsive doses of strychnine. Physiology & behavior 20040101
HMBC-RELAY: a combined technique for the differentiation of simultaneously detected 2J(C,H) and (n)J(C,H) connectivities. Magnetic resonance in chemistry : MRC 20040101
Paraventricular nucleus activation of renal sympathetic neurones is synaptically depressed by nitric oxide and glycine acting at a spinal level. Neuroscience 20040101
Extrinsic factors regulate partial agonist efficacy of strychnine-sensitive glycine receptors. BMC pharmacology 20040101
Functional glutamatergic and glycinergic inputs to several superior olivary nuclei of the rat revealed by optical imaging. Neuroscience 20040101
[Study of toxicology of strychnos]. Fa yi xue za zhi 20040101
Characterization of inhibitory postsynaptic currents in rod bipolar cells of the mouse retina. Visual neuroscience 20040101
Contralateral input modulates the excitability of dorsal horn neurons involved in noxious signal processes. Potential role in neuronal sensitization. Somatosensory & motor research 20040101
Antipanic procedures reduce the strychnine-facilitated wild running of rats. Behavioural brain research 20031217
Effect of metabotropic glutamate receptor activity on rhythmic discharges of the neonatal rat spinal cord in vitro. Experimental brain research 20031201
Antiallodynic effects of intrathecal orexins in a rat model of postoperative pain. The Journal of pharmacology and experimental therapeutics 20031201
Differential sensitivity of genetically Fast vs. Slow kindling rats strains to GABAergic convulsive agents. Neuropharmacology 20031201
Hypothalamic digoxin, hemispheric chemical dominance, and mesenteric artery occlusion. The International journal of neuroscience 20031201
Contribution of spinal inhibitory receptors in heterosegmental antinociception induced by noxious stimulation. The European journal of neuroscience 20031201
Quantitative analysis of strychnine and Brucine in Strychnos nux-vomica using 1H-NMR. Planta medica 20031201
Glycinergic input to carp retinal ganglion cells may be mediated by glycine receptors with homologous kinetics. Brain research 20031121
Inactivation of the glycine transporter 1 gene discloses vital role of glial glycine uptake in glycinergic inhibition. Neuron 20031113
Role of inhibitory amino acids in control of hypoglossal motor outflow to genioglossus muscle in naturally sleeping rats. The Journal of physiology 20031101
Central properties of the essential oil and the crude ethanol extract from aerial parts of Artemisia annua L. Pharmacological research 20031101
Effects of corticotropin-releasing factor on plasticity of optically recorded neuronal activity in the substantia gelatinosa of rat spinal cord slices. Pain 20031101
Functional expression and properties of a nicotinic alpha9/5-HT3A chimeric receptor. Neuroreport 20031027
Asymmetric cross-inhibition between GABAA and glycine receptors in rat spinal dorsal horn neurons. The Journal of biological chemistry 20031003
Mechanisms of H+ modulation of glycinergic response in rat sacral dorsal commissural neurons. The Journal of physiology 20031001
Analgesic and anti-inflammatory properties of brucine and brucine N-oxide extracted from seeds of Strychnos nux-vomica. Journal of ethnopharmacology 20031001
Distinct subtypes of group I metabotropic glutamate receptors on rat spinal neurons mediate complex facilitatory and inhibitory effects. The European journal of neuroscience 20031001
Glycine receptor knock-in mice and hyperekplexia-like phenotypes: comparisons with the null mutant. The Journal of neuroscience : the official journal of the Society for Neuroscience 20030903
'In vivo' monitoring of neuronal network activity in zebrafish by two-photon Ca(2+) imaging. Pflugers Archiv : European journal of physiology 20030901
GABAA and glycine receptors in regulation of intercostal and abdominal expiratory activity in vitro in neonatal rat. The Journal of physiology 20030901
Evidence for strychnine-sensitive glycine receptors in human amygdala. Naunyn-Schmiedeberg's archives of pharmacology 20030901
Inhibitory effect of intrathecal glycine on the micturition reflex in normal and spinal cord injury rats. Experimental neurology 20030901
A novel and general synthetic pathway to strychnos indole alkaloids: total syntheses of (-)-tubifoline, (-)-dehydrotubifoline, and (-)-strychnine using palladium-catalyzed asymmetric allylic substitution. Journal of the American Chemical Society 20030813
Glycine facilitates transmitter release at developing synapses: a patch clamp study from Purkinje neurons of the newborn rat. Brain research. Developmental brain research 20030812
Involvement of intracellular calcium and protein phosphatases in long-term depression of A-fiber-mediated primary afferent neurotransmission. Brain research. Developmental brain research 20030812
Characterization of spontaneous synaptic transmission in rat medial vestibular nucleus. Neuroreport 20030806
Neither spinal gamma-aminobutyric acid-A nor strychnine-sensitive glycine receptor systems are the sole mediators of halothane depression of spinal dorsal horn sensory neurons. Anesthesia and analgesia 20030801
Effects of some transmitters on resting membrane potential of somatic cell in Lumbricus terrestris muscle wall. Bulletin of experimental biology and medicine 20030801
Inactivation of amino acid receptors in medullary reticular formation modulates and suppresses ingestion and rejection responses in the awake rat. American journal of physiology. Regulatory, integrative and comparative physiology 20030701
Fast multi-dimensional Hadamard spectroscopy. Journal of magnetic resonance (San Diego, Calif. : 1997) 20030701
Strychnine intoxication in a child. The Israel Medical Association journal : IMAJ 20030701
Strychnine poisoning. The Journal of the Association of Physicians of India 20030701
Specific strychnine binding sites on acrosome-associated membranes of golden hamster spermatozoa. Biochemical and biophysical research communications 20030627
Posttraining lesion of the superior colliculus interferes with feature-negative discrimination of fear-potentiated startle. Behavioural brain research 20030616
Bisquaternary dimers of strychnine and brucine. A new class of potent enhancers of antagonist binding to muscarinic M2 receptors. Bioorganic & medicinal chemistry 20030612
Involvement of the GABAergic system for Ptychodiscus brevis toxin-induced depression of synaptic transmission elicited in isolated spinal cord from neonatal rats. Brain research 20030606
New corticocuneate cellular mechanisms underlying the modulation of cutaneous ascending transmission in anesthetized cats. Journal of neurophysiology 20030601
Two-dimensional Hadamard spectroscopy. Journal of magnetic resonance (San Diego, Calif. : 1997) 20030601
Highly sensitive reaction of nitrate with brucine and 3-methyl-2-benzothiazolinone hydrazone hydrochloride for the determination of nitrate in environmental samples. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20030601
[Pharmacokinetics of the alkaloids from the processed seeds of Strychnos nux-vomica in rats]. Yao xue xue bao = Acta pharmaceutica Sinica 20030601
Endogenous acetylcholine and nicotine activation enhances GABAergic and glycinergic inputs to cardiac vagal neurons. Journal of neurophysiology 20030501
Capillary electrophoresis with field-enhanced stacking for rapid and sensitive determination of strychnine and brucine. Analytical and bioanalytical chemistry 20030501
Frequency-domain Hadamard spectroscopy. Journal of magnetic resonance (San Diego, Calif. : 1997) 20030501
Ethanol potentiation of glycine receptors expressed in Xenopus oocytes antagonized by increased atmospheric pressure. Alcoholism, clinical and experimental research 20030501
Pressor response to chemoreflex activation before and after microinjection of glycine into the NTS of awake rats. American journal of physiology. Regulatory, integrative and comparative physiology 20030401
Cellular mechanisms of the trigeminally evoked startle response. The European journal of neuroscience 20030401
Identification of active thoracic spinal segments responsible for tonic and bursting sympathetic discharge in neonatal rats. Brain research 20030321
Role of EphA4 and EphrinB3 in local neuronal circuits that control walking. Science (New York, N.Y.) 20030321
GABA(A) receptor blockade antagonizes the immobilizing action of propofol but not ketamine or isoflurane in a dose-related manner. Anesthesia and analgesia 20030301
Strychnine-sensitive glycine receptors depress hyperexcitability in rat dentate gyrus. Journal of neurophysiology 20030301
Integrating mind and brain: Warren S. McCulloch, cerebral localization, and experimental epistemology. Endeavour 20030301
Apoptosis induction in human cancer cells by sungucine from Strychnos icaja root. Naunyn-Schmiedeberg's archives of pharmacology 20030301
Beta-alanine acts on glycine receptors in the rat sacral dorsal commissural neurons. The International journal of neuroscience 20030301
Design and synthesis of semicarbazones and their bio-isosteric analogues as potent anticonvulsants: the role of hydrogen bonding. Acta pharmaceutica (Zagreb, Croatia) 20030301
Effects of ginsenosides on glycine receptor alpha1 channels expressed in Xenopus oocytes. Molecules and cells 20030227
Effects of chronic ethanol consumption on rat GABA(A) and strychnine-sensitive glycine receptors expressed by lateral/basolateral amygdala neurons. Brain research 20030214
Indolomonoterpenic alkaloids from Strychnos icaja roots. Phytochemistry 20030201
Intentional poisoning of animals in southeastern Spain: a review of the veterinary toxicology service from Murcia, Spain. Veterinary and human toxicology 20030201
Fe2+ decreases the taurine-induced Cl- current in acutely dissociated rat hippocampal neurons. Brain research 20030117
Glycine receptors mediate part of the immobility produced by inhaled anesthetics. Anesthesia and analgesia 20030101
GABA-mediated inhibition of glutamate release during ischemia in substantia gelatinosa of the adult rat. Journal of neurophysiology 20030101
The neuronal targets for GABAergic reticulospinal inhibition that stops swimming in hatchling frog tadpoles. Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology 20030101
Psychopharmacological effects of tianeptine analogous hetero[2,1] benzothiazepine derivatives. Arzneimittel-Forschung 20030101
Bicuculline and strychnine suppress the mesencephalic locomotor region-induced inhibition of group III muscle afferent input to the dorsal horn. Neuroscience 20030101
Studies on brain biogenic amines in methanolic extract of Cuscuta reflexa Roxb. and Corchorus olitorius Linn. seed treated mice. Acta poloniae pharmaceutica 20030101
Influence of some convulsant agents on the protective activity of a novel antiepileptic drug, felbamate, against maximal electroshock in mice. Polish journal of pharmacology 20030101
Reduction of glycine receptor-mediated miniature inhibitory postsynaptic currents in rat spinal lamina I neurons after peripheral inflammation. Neuroscience 20030101
A combined blockade of glycine and calcium-dependent potassium channels abolishes the respiratory rhythm. Neuroscience 20030101
Effect of some convulsants on the protective activity of loreclezole and its combinations with valproate or clonazepam in amygdala-kindled rats. Polish journal of pharmacology 20030101
Enantioselective total synthesis of (-)-strychnine using the catalytic asymmetric Michael reaction and tandem cyclization. Journal of the American Chemical Society 20021211
Dual action of olivocochlear collaterals in the guinea pig cochlear nucleus. Hearing research 20021201
Dual cooperative allosteric modulation of binding to ionotropic glycine receptors. Neuropharmacology 20021201
Influence of several convulsants on the protective activity of a non-competitive AMPA/kainate antagonist, LY 300164, and lamotrigine against maximal electroshock in mice. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20021201
[HPLC determination of strychnine and brucine in Semen Strychni and its processed products]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20021201
Activation of 5HT1B receptors inhibits glycinergic synaptic inputs to mammalian motoneurons during postnatal development. Brain research 20021129
Glycine at hypoglossal motor nucleus: genioglossus activity, CO(2) responses, and the additive effects of GABA. Journal of applied physiology (Bethesda, Md. : 1985) 20021101
Fast synaptic transmission mediated by alpha-bungarotoxin-sensitive nicotinic acetylcholine receptors in lamina X neurones of neonatal rat spinal cord. The Journal of physiology 20021101
CNS inhibitory effects of barakol, a constituent of Cassia siamia Lamk. Journal of ethnopharmacology 20021101
Nicotinic receptors regulate the release of glycine onto lamina X neurones of the rat spinal cord. Neuropharmacology 20021101
Quantifying fear potentiated startle using absolute versus proportional increase scoring methods: implications for the neurocircuitry of fear and anxiety. Psychopharmacology 20021101
The lemniscal-cuneate recurrent excitation is suppressed by strychnine and enhanced by GABAA antagonists in the anaesthetized cat. The European journal of neuroscience 20021101
[Fatal strychnine intoxication. A case report]. Annales de medecine interne 20021101
Gasping is elicited by briefer hypoxia or ischemia following blockade of glycinergic transmission. Respiratory physiology & neurobiology 20021023
The actions of propofol on gamma-aminobutyric acid-A and glycine receptors in acutely dissociated spinal dorsal horn neurons of the rat. Anesthesia and analgesia 20021001
Binding site stoichiometry and the effects of phosphorylation on human alpha1 homomeric glycine receptors. The Journal of physiology 20021001
Role of synaptic inhibition in turtle respiratory rhythm generation. The Journal of physiology 20021001
Long-lasting enhancement of corticostriatal neurotransmission by taurine. The European journal of neuroscience 20021001
Central control of upper airway resistance regulating respiratory airflow in mammals. Journal of anatomy 20021001
Endogenous strychnine: description of hypo- and hyperstrychninergic state in relation to neuropsychiatric diseases. The International journal of neuroscience 20021001
Glycine receptors and transporters on bullfrog retinal Müller cells. Neuroreport 20020916
A glycine receptor antagonist, strychnine, blocked NMDA receptor activation in the neonatal mouse neocortex. Neuroreport 20020916
Optical imaging of glycinergic inhibition in the vestibular and cochlear nuclei. Brain research 20020913
Neurogenesis of gasping does not require inhibitory transmission using GABA(A) or glycine receptors. Respiratory physiology & neurobiology 20020904
Electrophysiological evidence for expression of glycine receptors in freshly isolated neurons from nucleus accumbens. The Journal of pharmacology and experimental therapeutics 20020901
Potential switch from eupnea to fictive gasping after blockade of glycine transmission and potassium channels. American journal of physiology. Regulatory, integrative and comparative physiology 20020901
Glycinergic inhibition is essential for co-ordinating cranial and spinal respiratory motor outputs in the neonatal rat. The Journal of physiology 20020901
High-resolution capillary tube NMR. A miniaturized 5-microL high-sensitivity TXI probe for mass-limited samples, off-line LC NMR, and HT NMR. Analytical chemistry 20020901
Anesthetic and ethanol effects on spontaneously opening glycine receptor channels. Journal of neurochemistry 20020901
Decay of ethanol-induced suppression of glycine-activated current of ventral tegmental area neurons. Neuropharmacology 20020901
Microinjections of glycine into the pre-Bötzinger complex inhibit phrenic nerve activity in the rat. Brain research 20020823
Morphine-3beta-D-glucuronide suppresses inhibitory synaptic transmission in rat substantia gelatinosa. The Journal of pharmacology and experimental therapeutics 20020801
Halothane suppression of spinal sensory neuronal responses to noxious peripheral stimuli is mediated, in part, by both GABA(A) and glycine receptor systems. Anesthesiology 20020801
Functional glycine receptor maturation in the absence of glycinergic input in dopaminergic neurones of the rat substantia nigra. The Journal of physiology 20020801
Experimental and modeling studies of novel bursts induced by blocking na(+) pump and synaptic inhibition in the rat spinal cord. Journal of neurophysiology 20020801
An anticonvulsant profile of the ketogenic diet in the rat. Epilepsy research 20020801
Herbal medicine causing likely strychnine poisoning. Human & experimental toxicology 20020801
Hyperekplexia mutation of glycine receptors: decreased gating efficacy with altered binding thermodynamics. Biochemical pharmacology 20020715
Atypical time course of clinical signs in a dog poisoned by strychnine. The Veterinary record 20020706
Anticonvulsive activity of Butea monosperma flowers in laboratory animals. Pharmacology, biochemistry, and behavior 20020701
State-related inhibition by GABA and glycine of transmission in Clarke's column. The Journal of neuroscience : the official journal of the Society for Neuroscience 20020701
Apoptosis of HL-60 leukemia cells induced by the bisindole alkaloids sungucine and isosungucine from Strychnos icaja. Planta medica 20020701
Cloning and functional characterization of two glycine receptor alpha-subunits from the perch retina. The European journal of neuroscience 20020701
Proconvulsant-induced seizures in alpha(4) nicotinic acetylcholine receptor subunit knockout mice. Neuropharmacology 20020701
Total synthesis of (-)-strychnine. Angewandte Chemie (International ed. in English) 20020603
BN52021, a platelet activating factor antagonist, is a selective blocker of glycine-gated chloride channel. Neurochemistry international 20020601
Auditory response properties in the superior paraolivary nucleus of the gerbil. Journal of neurophysiology 20020601
Roles of inhibition for transforming binaural properties in the brainstem auditory system. Hearing research 20020601
Experiments to detect long-range heteronuclear shift correlations: LR-J-HSMQC. Journal of magnetic resonance (San Diego, Calif. : 1997) 20020601
The discriminative stimulus effects of pentylenetetrazol as a model of anxiety: recent developments. Neuroscience and biobehavioral reviews 20020601
Precise inhibition is essential for microsecond interaural time difference coding. Nature 20020530
Asymmetric carbon-carbon coupling of phenols or anilines with aryllead triacetates. Journal of the American Chemical Society 20020515
Sensory activation and role of inhibitory reticulospinal neurons that stop swimming in hatchling frog tadpoles. The Journal of neuroscience : the official journal of the Society for Neuroscience 20020515
An M-like outward current regulates the excitability of spinal motoneurones in the adult turtle. The Journal of physiology 20020501
Trigeminal reflex regulation of the glottis depends on central glycinergic inhibition in the rat. American journal of physiology. Regulatory, integrative and comparative physiology 20020401
Regulation of the respiratory central pattern generator by chloride-dependent inhibition during development in the bullfrog (Rana catesbeiana). The Journal of experimental biology 20020401
Nitric oxide facilitates GABAergic neurotransmission in the cat oculomotor system: a physiological mechanism in eye movement control. The Journal of physiology 20020401
Evidence of a functionally segregated pathway from dorsal cochlear nucleus to inferior colliculus. Journal of neurophysiology 20020401
Incidence of intentional poisoning of dogs in the Abruzzo region of Italy. Veterinary and human toxicology 20020401
Functional glycine receptors are expressed by postnatal nestin-positive neural stem/progenitor cells. The European journal of neuroscience 20020401
Pharmacological characterization of glycine-gated chloride currents recorded in rat hippocampal slices. Journal of neurophysiology 20020301
Inhibition of spinal or hypoglossal motoneurons of the newborn rat by glycine or GABA. The European journal of neuroscience 20020301
Rodenticides. The Veterinary clinics of North America. Small animal practice 20020301
Transgenic expression of a mutant glycine receptor decreases alcohol sensitivity of mice. The Journal of pharmacology and experimental therapeutics 20020201
Strychnine-blocked glycine receptor is removed from synapses by a shift in insertion/degradation equilibrium. Molecular and cellular neurosciences 20020201
A role for the human sperm glycine receptor/Cl(-) channel in the acrosome reaction initiated by recombinant ZP3. Biology of reproduction 20020101
Relative contributions of bipolar cell and amacrine cell inputs to light responses of ON, OFF and ON-OFF retinal ganglion cells. Vision research 20020101
Alpha-adrenoreceptor activation modulates swimming via glycinergic and GABAergic inhibitory pathways in Xenopus laevis tadpoles. The European journal of neuroscience 20020101
Cerebellar input to magnocellular neurons in the red nucleus of the mouse: synaptic analysis in horizontal brain slices incorporating cerebello-rubral pathways. Neuroscience 20020101
NMDA and strychnine diversely modulate spinal dorsal horn noxious responsiveness in normal rats: potential significance to sensory disorders in neuropathic pain. Somatosensory & motor research 20020101
[Natural toxins in inter- and intraspecies interaction of human being (elements of ethnotoxinology)]. Zhurnal obshchei biologii 20020101
Nux vomica and animal experiments. Homeopathy : the journal of the Faculty of Homeopathy 20020101
Does the neurotransmitter transporter underlie adaptation at a histaminergic photoreceptor synapse? Visual neuroscience 20020101
Case report: Survival after deliberate strychnine self-poisoning, with toxicokinetic data. Critical care (London, England) 20020101
GABAergic and glycinergic neural inhibition in excitatory frequency tuning of bat inferior collicular neurons. Experimental brain research 20011201
NMDA receptor-dependent periodic oscillations in cultured spinal cord networks. Journal of neurophysiology 20011201
Strychnine alters response properties of trigeminal nociceptive neurons in the rat. Journal of neurophysiology 20011201
Centrally administered corticotropin-releasing hormone and peripheral injections of strychnine hydrochloride potentiate the acoustic startle response in preweanling rats. Behavioral neuroscience 20011201
Glycine receptor-mediated inhibition of dopamine and non-dopamine neurons of the rat ventral tegmental area in vitro. Brain research 20011123
Case 12-2001: Strychnine poisoning. The New England journal of medicine 20011122
Anticonvulsant activities of ethanolic extract and aqueous fraction isolated from Delphinium denudatum. Journal of ethnopharmacology 20011101
Glycine activates myenteric neurones in adult guinea-pigs. The Journal of physiology 20011101
Enzymatic and non-enzymatic reduction of brucine N-oxide by aldehyde oxidase and catalase. Xenobiotica; the fate of foreign compounds in biological systems 20011101
Woodward, Robinson, and strychnine: chemical structure and chemists' challenge. Ambix 20011101
[Experimental pharmacodynamic study on the anti-convulsion effect of shenpu decoction]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20011101
[Study on anticonvulsive effect of rhizoma pinelliae]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20011101
[Arsenic and strychnine against tired eyes]. Lakartidningen 20011010
The central nervous effects of Mitragyna africanus (Willd) stembark extract in rats. Journal of ethnopharmacology 20011001
Characterization of the spontaneous synaptic activity of amacrine cells in the mouse retina. Journal of neurophysiology 20011001
Are homeopathic studies better-fated in India? Forschende Komplementarmedizin und klassische Naturheilkunde = Research in complementary and natural classical medicine 20011001
Synchronization of an embryonic network of identified spinal interneurons solely by electrical coupling. Neuron 20010927
Approaches to the synthesis of (+/-)-strychnine via the cobalt-mediated [2 + 2 + 2] cycloaddition: rapid assembly of a classic framework. Journal of the American Chemical Society 20010926
Iontophoresis in vivo demonstrates a key role for GABA(A) and glycinergic inhibition in shaping frequency response areas in the inferior colliculus of guinea pig. The Journal of neuroscience : the official journal of the Society for Neuroscience 20010915
The release of spinal prostaglandin E2 and the effect of nitric oxide synthetase inhibition during strychnine-induced allodynia. Anesthesia and analgesia 20010901
Electrophysiological evidence for vasopressin V(1) receptors on neonatal motoneurons, premotor and other ventral horn neurons. Journal of neurophysiology 20010901
Mechanisms that initiate spontaneous network activity in the developing chick spinal cord. Journal of neurophysiology 20010901
Homeostatic plasticity induced by chronic block of AMPA/kainate receptors modulates the generation of rhythmic bursting in rat spinal cord organotypic cultures. The European journal of neuroscience 20010901
Biogenetically inspired approach to the Strychnos alkaloids. Concise syntheses of (+/-)-akuammicine and (+/-)-strychnine. Journal of the American Chemical Society 20010822
IPSC kinetics at identified GABAergic and mixed GABAergic and glycinergic synapses onto cerebellar Golgi cells. The Journal of neuroscience : the official journal of the Society for Neuroscience 20010815
Opposing effects of molecular volume and charge at the hyperekplexia site alpha 1(P250) govern glycine receptor activation and desensitization. The Journal of biological chemistry 20010810
Reversal of chloroquine and mefloquine resistance in Plasmodium falciparum by the two monoindole alkaloids, icajine and isoretuline. Planta medica 20010801
Determination of berberine and strychnine in medicinal plants and herbal preparations by pressurized liquid extraction with capillary zone electrophoresis. Electrophoresis 20010801
A critical role of the strychnine-sensitive glycinergic system in spontaneous retinal waves of the developing rabbit. The Journal of neuroscience : the official journal of the Society for Neuroscience 20010715
Developmental changes in 5-hydroxytryptamine-induced rhythmic activity in the spinal cord of rat fetuses in vitro. Neuroscience letters 20010706
Reversible inactivation of the dorsal nucleus of the lateral lemniscus reveals its role in the processing of multiple sound sources in the inferior colliculus of bats. The Journal of neuroscience : the official journal of the Society for Neuroscience 20010701
Transition from GABAergic to glycinergic synaptic transmission in newly formed spinal networks. Journal of neurophysiology 20010701
Spatiotemporal characterization of rhythmic activity in rat spinal cord slice cultures. The European journal of neuroscience 20010701
The generation of rhythmic activity in dissociated cultures of rat spinal cord. The European journal of neuroscience 20010701
Intraspinal amino acid neurotransmitter activities are involved in the generation of rhythmic sympathetic nerve discharge in newborn rat spinal cord. Brain research 20010615
Autoradiographic localization of [3H]thiocolchicoside binding sites in the rat brain and spinal cord. Neuropharmacology 20010601
Modification of the pacemaker activity of vestibular neurons in brainstem slices during vestibular compensation in the guinea pig. The European journal of neuroscience 20010601
Studies on psychopharmacological activity of Andrographis paniculata extract. Phytotherapy research : PTR 20010501
Ivermectin, an unconventional agonist of the glycine receptor chloride channel. The Journal of biological chemistry 20010420
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 12-2001. A 16-year-old boy with an altered mental status and muscle rigidity. The New England journal of medicine 20010419
Effects of brucine, a plant alkaloid, on M(1) muscarinic receptors and alpha(1)-adrenoceptors in the rabbit vas deferens preparation. Toxicon : official journal of the International Society on Toxinology 20010401
Bitter taste transduced by PLC-beta(2)-dependent rise in IP(3) and alpha-gustducin-dependent fall in cyclic nucleotides. American journal of physiology. Cell physiology 20010401
The co-occurrence of C(3) epimer Nb,C(21)-secocuran alkaloids in Strychnos diplotricha and Strychnos myrtoides. Phytochemistry 20010401
Strychnos nux-vomica extract and its ultra-high dilution reduce voluntary ethanol intake in rats. Journal of alternative and complementary medicine (New York, N.Y.) 20010401
Nux vomica 30 prepared with and without succession shows antialcoholic effect on toads and distinctive molecular association. The British homoeopathic journal 20010401
Interactions between allosteric modulators and 4-DAMP and other antagonists at muscarinic receptors: potential significance of the distance between the N and carboxyl C atoms in the molecules of antagonists. Neurochemical research 20010401
Effects of pituitary adenylate cyclase activating polypeptide on lumbosacral preganglionic neurons in the neonatal rat spinal cord. Brain research 20010323
Glycine receptor mediated responses in rat histaminergic neurons. Neuroscience letters 20010302
Coadministration of intrathecal strychnine and bicuculline effects synergistic allodynia in the rat: an isobolographic analysis. The Journal of pharmacology and experimental therapeutics 20010301
Protection of ATP-depleted cells by impermeant strychnine derivatives: implications for glycine cytoprotection. The American journal of pathology 20010301
Hamster sperm glycine receptor: evidence for its presence and involvement in the acrosome reaction. Molecular reproduction and development 20010201
Spectral integration in the inferior colliculus: role of glycinergic inhibition in response facilitation. The Journal of neuroscience : the official journal of the Society for Neuroscience 20010201
Electrophysiologic evidence for increased endogenous gabaergic but not glycinergic inhibitory tone in the rat spinal nerve ligation model of neuropathy. Anesthesiology 20010201
A nonsense mutation in the alpha1 subunit of the inhibitory glycine receptor associated with bovine myoclonus. Molecular and cellular neurosciences 20010201
Design of semicarbazones and their bio-isosteric analogues as potential anticonvulsants. Die Pharmazie 20010201
Neither GABA(A) nor strychnine-sensitive glycine receptors are the sole mediators of MAC for isoflurane. Anesthesia and analgesia 20010101
Slow dorsal-ventral rhythm generator in the lamprey spinal cord. Journal of neurophysiology 20010101
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