Home Halogens Dichloro(1R,2R-cyclohexanediammine)platinum(II)

Dichloro(1R,2R-cyclohexanediammine)platinum(II)

CAS No.:
61848-66-6
Catalog Number:
AG00EFT3
Molecular Formula:
Molecular Weight:
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
98%
In Stock USA
United States
$226
- +
25mg
98%
In Stock USA
United States
$847
- +
Product Description
Catalog Number:
AG00EFT3
Chemical Name:
Dichloro(1R,2R-cyclohexanediammine)platinum(II)
CAS Number:
61848-66-6
MDL Number:
MFCD00058826
IUPAC Name:
(2-azanidylcyclohexyl)azanide;dichloroplatinum(2+)
InChI:
InChI=1S/C6H12N2.2ClH.Pt/c7-5-3-1-2-4-6(5)8;;;/h5-8H,1-4H2;2*1H;/q-2;;;+4/p-2
InChI Key:
UUERTZXRKZEANK-UHFFFAOYSA-L
Properties
Complexity:
84.7  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
377.003g/mol
Formal Charge:
0
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
378.16g/mol
Monoisotopic Mass:
377.003g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
2A^2
Undefined Atom Stereocenter Count:
2  
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
Bioactive polymeric metallosomes self-assembled through block copolymer-metal complexation. Journal of the American Chemical Society 20120815
Polymeric micelles incorporating (1,2-diaminocyclohexane)platinum (II) suppress the growth of orthotopic scirrhous gastric tumors and their lymph node metastasis. Journal of controlled release : official journal of the Controlled Release Society 20120430
Visible drug delivery by supramolecular nanocarriers directing to single-platformed diagnosis and therapy of pancreatic tumor model. Cancer research 20100915
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Cross-links of quadruplex structures from human telomeric DNA by dinuclear platinum complexes show the flexibility of both structures. Biochemistry 20050809
Preparation and biological properties of dichloro(1,2-diaminocyclohexane)platinum(II) (DACHPt)-loaded polymeric micelles. Journal of controlled release : official journal of the Controlled Release Society 20050103
Tamoxifen derivatives for delivery of the antitumoral (DACH)Pt group: selective synthesis by McMurry coupling, and biochemical behaviour. Chembiochem : a European journal of chemical biology 20030804
A platinum(IV) complex oxidizes guanine to 8-oxo-guanine in DNA and RNA. Inorganic chemistry 20011022
A possible explanation for a neurotoxic effect of the anticancer agent oxaliplatin on neuronal voltage-gated sodium channels. Journal of neurophysiology 20010501
Properties