11-cis Retinal
Title | Journal |
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Characterization of human short chain dehydrogenase/reductase SDR16C family members related to retinol dehydrogenase 10. | Chemico-biological interactions 20171001 |
All-trans-retinal dimer formation alleviates the cytotoxicity of all-trans-retinal in human retinal pigment epithelial cells. | Toxicology 20160914 |
The retinaldehyde reductase DHRS3 is essential for preventing the formation of excess retinoic acid during embryonic development. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20131201 |
Aldo-keto reductases in retinoid metabolism: search for substrate specificity and inhibitor selectivity. | Chemico-biological interactions 20130225 |
All-trans retinal mediates light-induced oxidation in single living rod photoreceptors. | Photochemistry and photobiology 20121101 |
Retinal photodamage mediated by all-trans-retinal. | Photochemistry and photobiology 20121101 |
Evidence for the Two-State-Two-Mode model in retinal protonated Schiff-bases from pump degenerate four-wave-mixing experiments. | Physical chemistry chemical physics : PCCP 20121028 |
Ultrafast photochemistry of light-adapted and dark-adapted bacteriorhodopsin: effects of the initial retinal configuration. | The journal of physical chemistry. B 20120906 |
Adoptive transfer of all-trans-retinal-induced regulatory T cells ameliorates experimental autoimmune arthritis in an interferon-gamma knockout model. | Autoimmunity 20120901 |
A microparticle/hydrogel combination drug-delivery system for sustained release of retinoids. | Investigative ophthalmology & visual science 20120901 |
Excitation energies of retinal chromophores: critical role of the structural model. | Physical chemistry chemical physics : PCCP 20120821 |
Vitamin A metabolism in rod and cone visual cycles. | Annual review of nutrition 20120821 |
Distinct loops in arrestin differentially regulate ligand binding within the GPCR opsin. | Nature communications 20120807 |
Cultured Müller cells from mammals can synthesize and accumulate retinyl esters. | Experimental eye research 20120801 |
Critical role of Asp227 in the photocycle of proteorhodopsin. | Biochemistry 20120717 |
Photochemical properties of mammalian melanopsin. | Biochemistry 20120710 |
Increased cone sensitivity to ABCA4 deficiency provides insight into macular vision loss in Stargardt's dystrophy. | Biochimica et biophysica acta 20120701 |
Lipofuscin and N-retinylidene-N-retinylethanolamine (A2E) accumulate in retinal pigment epithelium in absence of light exposure: their origin is 11-cis-retinal. | The Journal of biological chemistry 20120622 |
Melanopsin is highly resistant to light and chemical bleaching in vivo. | The Journal of biological chemistry 20120615 |
The exciton origin of the visible circular dichroism spectrum of bacteriorhodopsin. | The journal of physical chemistry. B 20120614 |
An S-opsin knock-in mouse (F81Y) reveals a role for the native ligand 11-cis-retinal in cone opsin biosynthesis. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20120606 |
Tuning the primary reaction of channelrhodopsin-2 by imidazole, pH, and site-specific mutations. | Biophysical journal 20120606 |
Determination of vitamin A and its metabolites in rat testis: possible involvement of vitamin A in testicular toxicity caused by molinate. | Bulletin of environmental contamination and toxicology 20120601 |
Rapid release of retinal from a cone visual pigment following photoactivation. | Biochemistry 20120522 |
Vertebrate ancient opsin photopigment spectra and the avian photoperiodic response. | Biology letters 20120423 |
Increased blood oxidative stress in experimental menopause rat model: the effects of vitamin A low-dose supplementation upon antioxidant status in bilateral ovariectomized rats. | Fundamental & clinical pharmacology 20120401 |
Thermodynamic stability of bacteriorhodopsin mutants measured relative to the bacterioopsin unfolded state. | Biochimica et biophysica acta 20120401 |
Enhancement of retinal production by supplementing the surfactant Span 80 using metabolically engineered Escherichia coli. | Journal of bioscience and bioengineering 20120401 |
Insights into the activation mechanism of the visual receptor rhodopsin. | Biochemical Society transactions 20120401 |
New therapeutic targets in dermatoporosis. | The journal of nutrition, health & aging 20120401 |
Insight into molecular pathways of retinal metabolism, associated with vitellogenesis in zebrafish. | American journal of physiology. Endocrinology and metabolism 20120315 |
Expression and activity of alcohol and aldehyde dehydrogenases in melanoma cells and in melanocytes. | Journal of cellular biochemistry 20120301 |
The bisretinoids of retinal pigment epithelium. | Progress in retinal and eye research 20120301 |
The effect of protein environment on photoexcitation properties of retinal. | The journal of physical chemistry. B 20120223 |
Time-resolved spectroscopy of ultrafast photoisomerization of octopus rhodopsin under photoexcitation. | The journal of physical chemistry. B 20120216 |
Crystal structure of the channelrhodopsin light-gated cation channel. | Nature 20120216 |
Mechanism of all-trans-retinal toxicity with implications for stargardt disease and age-related macular degeneration. | The Journal of biological chemistry 20120210 |
Light-sensitive coupling of rhodopsin and melanopsin to G(i/o) and G(q) signal transduction in Caenorhabditis elegans. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120201 |
Primary amines protect against retinal degeneration in mouse models of retinopathies. | Nature chemical biology 20120201 |
Understanding rhodopsin mutations linked to the retinitis pigmentosa disease: a QM/MM and DFT/MRCI study. | The journal of physical chemistry. B 20120126 |
Population branching in the conical intersection of the retinal chromophore revealed by multipulse ultrafast optical spectroscopy. | Journal of the American Chemical Society 20120118 |
Chemistry and biology of vision. | The Journal of biological chemistry 20120113 |
Rod and cone visual pigments and phototransduction through pharmacological, genetic, and physiological approaches. | The Journal of biological chemistry 20120113 |
Key enzymes of the retinoid (visual) cycle in vertebrate retina. | Biochimica et biophysica acta 20120101 |
Mechanisms involved in the intestinal absorption of dietary vitamin A and provitamin A carotenoids. | Biochimica et biophysica acta 20120101 |
The mechanism of fenretinide (4-HPR) inhibition of β-carotene monooxygenase 1. New suspect for the visual side effects of fenretinide. | Advances in experimental medicine and biology 20120101 |
Molecular clues to Bothnia-type retinal dystrophy. | Advances in experimental medicine and biology 20120101 |
Acute systemic 11-cis-retinal intervention improves abnormal outer retinal ion channel closure in diabetic mice. | Molecular vision 20120101 |
Differential expression of the demosponge (Suberites domuncula) carotenoid oxygenases in response to light: protection mechanism against the self-produced toxic protein (Suberitine). | Marine drugs 20120101 |
[Photosensing by membrane-embedded receptors and its application for the life scientists]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20120101 |
Retinol metabolism in the mollusk Osilinus lineatus indicates an ancient origin for retinyl ester storage capacity. | PloS one 20120101 |
Cytotoxicity of all-trans-retinal increases upon photodegradation. | Photochemistry and photobiology 20120101 |
Comparative analysis of the heptahelical transmembrane bundles of G protein-coupled receptors. | PloS one 20120101 |
M-opsin protein degradation is inhibited by MG-132 in Rpe65⁻/⁻ retinal explant culture. | Molecular vision 20120101 |
A novel source of methylglyoxal and glyoxal in retina: implications for age-related macular degeneration. | PloS one 20120101 |
Retinal attenuates inflammatory arthritis by reciprocal regulation of IL-17-producing T cells and Foxp3(+) regulatory T cells and the inhibition of osteoclastogenesis. | Immunology letters 20120101 |
Probing a polar cluster in the retinal binding pocket of bacteriorhodopsin by a chemical design approach. | PloS one 20120101 |
The hepatic Raldh1 expression is elevated in Zucker fatty rats and its over-expression introduced the retinal-induced Srebp-1c expression in INS-1 cells. | PloS one 20120101 |
Light-induced damage to the retina: current understanding of the mechanisms and unresolved questions: a symposium-in-print. | Photochemistry and photobiology 20120101 |
Quantum mechanical/molecular mechanical structure, enantioselectivity, and spectroscopy of hydroxyretinals and insights into the evolution of color vision in small white butterflies. | The journal of physical chemistry. B 20111229 |
Vibrational analysis of excited and ground electronic states of all-trans retinal protonated Schiff-bases. | Physical chemistry chemical physics : PCCP 20111228 |
Retinaldehyde is a substrate for human aldo-keto reductases of the 1C subfamily. | The Biochemical journal 20111215 |
Vertebrate ancient-long opsin has molecular properties intermediate between those of vertebrate and invertebrate visual pigments. | Biochemistry 20111206 |
Expression of salinarum halorhodopsin in Escherichia coli cells: solubilization in the presence of retinal yields the natural state. | Biochimica et biophysica acta 20111201 |
Why 11-cis-retinal? Why not 7-cis-, 9-cis-, or 13-cis-retinal in the eye? | Journal of the American Chemical Society 20111130 |
UVA phototransduction drives early melanin synthesis in human melanocytes. | Current biology : CB 20111122 |
Molecular mechanisms of disease for mutations at Gly-90 in rhodopsin. | The Journal of biological chemistry 20111118 |
Human retinal pigment epithelium cells as functional models for the RPE in vivo. | Investigative ophthalmology & visual science 20111101 |
A novel bisretinoid of retina is an adduct on glycerophosphoethanolamine. | Investigative ophthalmology & visual science 20111101 |
Light activation of the isomerization and deprotonation of the protonated Schiff base retinal. | Journal of molecular modeling 20111001 |
Uncoupling of retinoic acid signaling from tailbud development before termination of body axis extension. | Genesis (New York, N.Y. : 2000) 20111001 |
Time-resolved WAXS reveals accelerated conformational changes in iodoretinal-substituted proteorhodopsin. | Biophysical journal 20110921 |
Temozolomide and 13-cis retinoic acid in patients with anaplastic gliomas: a prospective single-arm monocentric phase-II study (RNOP-05). | Journal of neuro-oncology 20110901 |
Alkylated hydroxylamine derivatives eliminate peripheral retinylidene Schiff bases but cannot enter the retinal binding pocket of light-activated rhodopsin. | Biochemistry 20110823 |
An amino acid residue (S201) in the retinal binding pocket regulates the photoreaction pathway of phoborhodopsin. | Biochemistry 20110823 |
H-bond network around retinal regulates the evolution of ultraviolet and violet vision. | ACS chemical biology 20110819 |
Thermal properties of rhodopsin: insight into the molecular mechanism of dim-light vision. | The Journal of biological chemistry 20110805 |
Steric and electronic influences on the torsional energy landscape of retinal. | Biophysical journal 20110803 |
Evidence from Chlamydomonas on the photoactivation of rhodopsins without isomerization of their chromophore. | Chemistry & biology 20110624 |
An intramolecular charge transfer state of carbonyl carotenoids: implications for excited state dynamics of apo-carotenals and retinal. | Physical chemistry chemical physics : PCCP 20110614 |
Structural characteristics around the β-ionone ring of the retinal chromophore in Salinibacter sensory rhodopsin I. | Biochemistry 20110607 |
Reduction of the virtual space for coupled-cluster excitation energies of large molecules and embedded systems. | The Journal of chemical physics 20110607 |
Retinaldehyde/hyaluronic acid fragments: a synergistic association for the management of skin aging. | Journal of cosmetic dermatology 20110601 |
Human and rodent aldo-keto reductases from the AKR1B subfamily and their specificity with retinaldehyde. | Chemico-biological interactions 20110530 |
Role of bulk water in hydrolysis of the rhodopsin chromophore. | The Journal of biological chemistry 20110527 |
Conserved Tyr223(5.58) plays different roles in the activation and G-protein interaction of rhodopsin. | Journal of the American Chemical Society 20110511 |
Macular degeneration: a possible biochemical mechanism. | Medical hypotheses 20110501 |
Binding affinities of CRBPI and CRBPII for 9-cis-retinoids. | Biochimica et biophysica acta 20110501 |
Toll-like receptor 3 is required for development of retinopathy caused by impaired all-trans-retinal clearance in mice. | The Journal of biological chemistry 20110429 |
Retinal and retinol are potential regulators of gene expression in the keratinocyte cell line HaCaT. | Experimental dermatology 20110401 |
Light prevents exogenous 11-cis retinal from maintaining cone photoreceptors in chromophore-deficient mice. | Investigative ophthalmology & visual science 20110401 |
Spectral tuning in sensory rhodopsin I from Salinibacter ruber. | The Journal of biological chemistry 20110401 |
The structural basis of agonist-induced activation in constitutively active rhodopsin. | Nature 20110331 |
Crystal structure of metarhodopsin II. | Nature 20110331 |
Cyclopropyl and isopropyl derivatives of 11-cis and 9-cis retinals at C-9 and C-13: subtle steric differences with major effects on ligand efficacy in rhodopsin. | Journal of natural products 20110325 |
Probing human red cone opsin activity with retinal analogues. | Journal of natural products 20110325 |
Retinoids synergized with insulin to induce Srebp-1c expression and activated its promoter via the two liver X receptor binding sites that mediate insulin action. | Biochemical and biophysical research communications 20110311 |
Product formation in rhodopsin by fast hydrogen motions. | Physical chemistry chemical physics : PCCP 20110307 |
Retinal dynamics underlie its switch from inverse agonist to agonist during rhodopsin activation. | Nature structural & molecular biology 20110301 |
Coherent control of the isomerization of retinal in bacteriorhodopsin in the high intensity regime. | The Journal of chemical physics 20110227 |
Large-scale production of a disulfide-stabilized constitutively active mutant opsin. | Protein expression and purification 20110201 |
Photochemistry of a putative new class of sensory rhodopsin (SRIII) coded by xop2 of Haloarcular marismortui. | Journal of photochemistry and photobiology. B, Biology 20110110 |
Second-harmonic generation imaging of membrane potential with retinal analogues. | Biophysical journal 20110105 |
Milk, revealed 'silent' chemistry: new mode of cycloretinal synthesis. | Molecular bioSystems 20110101 |
Water pathways in the bacteriorhodopsin proton pump. | The Journal of membrane biology 20110101 |
Retinal release from opsin in molecular dynamics simulations. | Journal of molecular recognition : JMR 20110101 |
Regulation of gene expression by retinoids. | Current medicinal chemistry 20110101 |
Altered expression of β-galactosidase-1-like protein 3 (Glb1l3) in the retinal pigment epithelium (RPE)-specific 65-kDa protein knock-out mouse model of Leber's congenital amaurosis. | Molecular vision 20110101 |
Effects of mutations of Lys41 and Asp102 of bacteriorhodopsin. | Bioscience, biotechnology, and biochemistry 20110101 |
Retinoid production using metabolically engineered Escherichia coli with a two-phase culture system. | Microbial cell factories 20110101 |
UV-sensitive photoreceptor protein OPN5 in humans and mice. | PloS one 20110101 |
High glucose increases lysyl oxidase expression and activity in retinal endothelial cells: mechanism for compromised extracellular matrix barrier function. | Diabetes 20101201 |
Exonic SINE insertion in STK38L causes canine early retinal degeneration (erd). | Genomics 20101201 |
QM/MM study of dehydro and dihydro β-ionone retinal analogues in squid and bovine rhodopsins: implications for vision in salamander rhodopsin. | Journal of the American Chemical Society 20101117 |
The contribution of a covalently bound cofactor to the folding and thermodynamic stability of an integral membrane protein. | Journal of molecular biology 20101105 |
Parallel visual cycles in the zebrafish retina. | Progress in retinal and eye research 20101101 |
Effective and sustained delivery of hydrophobic retinoids to photoreceptors. | Investigative ophthalmology & visual science 20101101 |
Hydroxylamine as a thermal destabiliser of bacteriorhodopsin. | European biophysics journal : EBJ 20101101 |
Improvement of visual performance with intravitreal administration of 9-cis-retinal in Rpe65-mutant dogs. | Archives of ophthalmology (Chicago, Ill. : 1960) 20101101 |
Functional analysis of the second extracellular loop of rhodopsin by characterizing split variants. | Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20101101 |
Blind dogs that can see: pharmacological treatment of Leber congenital amaurosis caused by a defective visual cycle. | Archives of ophthalmology (Chicago, Ill. : 1960) 20101101 |
[Evaluation of factors associated with variability in retinal nerve fiber layer thickness in myopic juveniles aged 7-18 years]. | [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20101101 |
Coupling of retinal, protein, and water dynamics in squid rhodopsin. | Biophysical journal 20101006 |
Biotransformation of carotenoids to retinal by carotenoid 15,15'-oxygenase. | Applied microbiology and biotechnology 20101001 |
Retinobenzaldehydes as proper-trafficking inducers of folding-defective P23H rhodopsin mutant responsible for retinitis pigmentosa. | Bioorganic & medicinal chemistry 20101001 |
Physical chemistry: Seaming is believing. | Nature 20100923 |
Conical intersection dynamics of the primary photoisomerization event in vision. | Nature 20100923 |
Retinoid storage in the egg of reptiles and birds. | Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20100901 |
Interpretations of fundus autofluorescence from studies of the bisretinoids of the retina. | Investigative ophthalmology & visual science 20100901 |
Lighting a candle in the dark: advances in genetics and gene therapy of recessive retinal dystrophies. | The Journal of clinical investigation 20100901 |
Topical retinoids induce β-defensin 3 expression in mouse skin. | International journal of dermatology 20100901 |
The efficacy of topical drugs in treatment of noninflammatory acne vulgaris. | Georgian medical news 20100901 |
Nonadiabatic ab initio dynamics of a model protonated Schiff base of 9-cis retinal. | The journal of physical chemistry. A 20100819 |
Involvement of the Hipk family in regulation of eyeball size, lens formation and retinal morphogenesis. | FEBS letters 20100716 |
Retinal production from beta-carotene by beta-carotene 15,15'-dioxygenase from an unculturable marine bacterium. | Biotechnology letters 20100701 |
Retinal very long-chain PUFAs: new insights from studies on ELOVL4 protein. | Journal of lipid research 20100701 |
Interaction of extracellular domain 2 of the human retina-specific ATP-binding cassette transporter (ABCA4) with all-trans-retinal. | The Journal of biological chemistry 20100618 |
Binding of anions to proteorhodopsin affects the Asp97 pK(a). | Biochemistry 20100601 |
Retinoids for treatment of retinal diseases. | Trends in pharmacological sciences 20100601 |
Acne rosacea: effectiveness of 532 nm laser on the cosmetic appearance of the skin. | Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale 20100601 |
Putative active states of a prototypic g-protein-coupled receptor from biased molecular dynamics. | Biophysical journal 20100519 |
Studies of the ground and excited-state surfaces of the retinal chromophore using CAM-B3LYP. | The journal of physical chemistry. B 20100429 |
Protein fluctuations as the possible origin of the thermal activation of rod photoreceptors in the dark. | Journal of the American Chemical Society 20100428 |
Low-temperature FTIR study of Gloeobacter rhodopsin: presence of strongly hydrogen-bonded water and long-range structural protein perturbation upon retinal photoisomerization. | Biochemistry 20100420 |
Sequential rearrangement of interhelical networks upon rhodopsin activation in membranes: the Meta II(a) conformational substate. | Journal of the American Chemical Society 20100407 |
Coherent ultrafast torsional motion and isomerization of a biomimetic dipolar photoswitch. | Physical chemistry chemical physics : PCCP 20100407 |
Induction of uncoupling protein-1 in mouse embryonic fibroblast-derived adipocytes by retinoic acid. | Obesity (Silver Spring, Md.) 20100401 |
Single doses of all-trans-N-retinylacetamide slow down the ERG amplitude recovery after bleaching in rats. | Documenta ophthalmologica. Advances in ophthalmology 20100401 |
Degenerate two-photon absorption in all-trans retinal: nonlinear spectrum and theoretical calculations. | The journal of physical chemistry. A 20100318 |
Regulation of photoreceptor gene expression by the retinal homeobox (Rx) gene product. | Developmental biology 20100315 |
Synthesis and use of stable isotope enriched retinals in the field of vitamin A. | Molecules (Basel, Switzerland) 20100315 |
Covalent bond between ligand and receptor required for efficient activation in rhodopsin. | The Journal of biological chemistry 20100312 |
A pivot between helices V and VI near the retinal-binding site is necessary for activation in rhodopsins. | The Journal of biological chemistry 20100305 |
{beta}-Apocarotenoids do not significantly activate retinoic acid receptors {alpha} or {beta}. | Experimental biology and medicine (Maywood, N.J.) 20100301 |
Molecular mechanisms of rhodopsin retinitis pigmentosa and the efficacy of pharmacological rescue. | Journal of molecular biology 20100205 |
A conserved aromatic lock for the tryptophan rotameric switch in TM-VI of seven-transmembrane receptors. | The Journal of biological chemistry 20100205 |
Phospholipid meets all-trans-retinal: the making of RPE bisretinoids. | Journal of lipid research 20100201 |
Retinal dynamics during light activation of rhodopsin revealed by solid-state NMR spectroscopy. | Biochimica et biophysica acta 20100201 |
NinaB is essential for Drosophila vision but induces retinal degeneration in opsin-deficient photoreceptors. | The Journal of biological chemistry 20100115 |
Rpe65 isomerase associates with membranes through an electrostatic interaction with acidic phospholipid headgroups. | The Journal of biological chemistry 20100108 |
Dependence of photochemical reactivity of the all-trans retinal protonated Schiff base on the solvent and the excitation wavelength. | Photochemistry and photobiology 20100101 |
The retinal pigment epithelium: something more than a constituent of the blood-retinal barrier--implications for the pathogenesis of diabetic retinopathy. | Journal of biomedicine & biotechnology 20100101 |
Structure and activation of the visual pigment rhodopsin. | Annual review of biophysics 20100101 |
Femtosecond formation dynamics of primary photoproducts of visual pigment rhodopsin. | Biochemistry. Biokhimiia 20100101 |
Cosmeceuticals: the evidence behind the retinoids. | Aesthetic surgery journal 20100101 |
Comparison of A2E cytotoxicity and phototoxicity with all-trans-retinal in human retinal pigment epithelial cells. | Photochemistry and photobiology 20100101 |
Quantification of endogenous retinoids. | Methods in molecular biology (Clifton, N.J.) 20100101 |
In vitro assays of rod and cone opsin activity: retinoid analogs as agonists and inverse agonists. | Methods in molecular biology (Clifton, N.J.) 20100101 |
Physiological studies of the interaction between opsin and chromophore in rod and cone visual pigments. | Methods in molecular biology (Clifton, N.J.) 20100101 |
Binding of retinoids to ABCA4, the photoreceptor ABC transporter associated with Stargardt macular degeneration. | Methods in molecular biology (Clifton, N.J.) 20100101 |
Molecular biology and analytical chemistry methods used to probe the retinoid cycle. | Methods in molecular biology (Clifton, N.J.) 20100101 |
Photoreceptor structure and function is maintained in organotypic cultures of mouse retinas. | Molecular vision 20100101 |
Bisretinoids of RPE lipofuscin: trigger for complement activation in age-related macular degeneration. | Advances in experimental medicine and biology 20100101 |
Synergistic effect of hyaluronate fragments in retinaldehyde-induced skin hyperplasia which is a Cd44-dependent phenomenon. | PloS one 20100101 |
Just in the nick of time: targeting acute versus chronic disease. | Oxidative medicine and cellular longevity 20100101 |
Reaction pathways of photoexcited retinal in proteorhodopsin studied by pump-dump-probe spectroscopy. | The journal of physical chemistry. B 20091217 |
Fluoro derivatives of retinal illuminate the decisive role of the C(12)-H element in photoisomerization and rhodopsin activation. | Journal of the American Chemical Society 20091216 |
Retinal-protein interactions in halorhodopsin from Natronomonas pharaonis: binding and retinal thermal isomerization catalysis. | Journal of molecular biology 20091204 |
Cortical dynamics of navigation and steering in natural scenes: Motion-based object segmentation, heading, and obstacle avoidance. | Neural networks : the official journal of the International Neural Network Society 20091201 |
Elucidating the exact role of engineered CRABPII residues for the formation of a retinal protonated Schiff base. | Proteins 20091201 |
Kinetic characterization of recombinant mouse retinal dehydrogenase types 3 and 4 for retinal substrates. | Biochimica et biophysica acta 20091201 |
Calnexin improves the folding efficiency of mutant rhodopsin in the presence of pharmacological chaperone 11-cis-retinal. | The Journal of biological chemistry 20091127 |
Reconstitution of Gloeobacter violaceus rhodopsin with a light-harvesting carotenoid antenna. | Biochemistry 20091124 |
Limited roles of Rdh8, Rdh12, and Abca4 in all-trans-retinal clearance in mouse retina. | Investigative ophthalmology & visual science 20091101 |
Color tuning in short wavelength-sensitive human and mouse visual pigments: ab initio quantum mechanics/molecular mechanics studies. | The journal of physical chemistry. A 20091029 |
Is the photoinduced isomerization in retinal protonated Schiff bases a single- or double-torsional process? | The journal of physical chemistry. A 20091029 |
6-s-cis Conformation and polar binding pocket of the retinal chromophore in the photoactivated state of rhodopsin. | Journal of the American Chemical Society 20091028 |
Evolution and the origin of the visual retinoid cycle in vertebrates. | Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20091012 |
Evolution of vertebrate retinal photoreception. | Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20091012 |
The evolution of early vertebrate photoreceptors. | Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20091012 |
Cone outer segment morphology and cone function in the Rpe65-/- Nrl-/- mouse retina are amenable to retinoid replacement. | Investigative ophthalmology & visual science 20091001 |
Identification and characterization of retinoid-active short-chain dehydrogenases/reductases in Drosophila melanogaster. | Biochimica et biophysica acta 20091001 |
Ustilago maydis accumulates beta-carotene at levels determined by a retinal-forming carotenoid oxygenase. | Fungal genetics and biology : FG & B 20091001 |
Picosecond time-resolved ultraviolet resonance Raman spectroscopy of bacteriorhodopsin: primary protein response to the photoisomerization of retinal. | The journal of physical chemistry. B 20090903 |
Retinal-salinixanthin interactions in xanthorhodopsin: [corrected] a circular dichroism (CD) spectroscopy study with artificial pigments. | Biochemistry 20090901 |
Allosteric communication between protomers of dopamine class A GPCR dimers modulates activation. | Nature chemical biology 20090901 |
Acceleration of the Z to E photoisomerization of penta-2,4-dieniminium by hydrogen out-of-plane motion: theoretical study on a model system of retinal protonated Schiff base. | Physical chemistry chemical physics : PCCP 20090814 |
Rlbp1 promoter drives robust Müller glial GFP expression in transgenic mice. | Investigative ophthalmology & visual science 20090801 |
Novel lipofuscin bisretinoids prominent in human retina and in a model of recessive Stargardt disease. | The Journal of biological chemistry 20090724 |
Definition of the G protein-coupled receptor transmembrane bundle binding pocket and calculation of receptor similarities for drug design. | Journal of medicinal chemistry 20090723 |
X-ray structure breakthroughs in the GPCR transmembrane region. | Biochemical pharmacology 20090701 |
Thermal decay of rhodopsin: role of hydrogen bonds in thermal isomerization of 11-cis retinal in the binding site and hydrolysis of protonated Schiff base. | Journal of the American Chemical Society 20090701 |
Loss of cone photoreceptors caused by chromophore depletion is partially prevented by the artificial chromophore pro-drug, 9-cis-retinyl acetate. | Human molecular genetics 20090615 |
In vitro characterization of a recombinant Blh protein from an uncultured marine bacterium as a beta-carotene 15,15'-dioxygenase. | The Journal of biological chemistry 20090605 |
Cryogenic sample exchange NMR probe for magic angle spinning dynamic nuclear polarization. | Journal of magnetic resonance (San Diego, Calif. : 1997) 20090601 |
Involvement of all-trans-retinal in acute light-induced retinopathy of mice. | The Journal of biological chemistry 20090529 |
Long-distance proton transfer with a break in the bacteriorhodopsin active site. | Journal of the American Chemical Society 20090527 |
Site-specific difference 2D-IR spectroscopy of bacteriorhodopsin. | The journal of physical chemistry. B 20090507 |
Retinoids synergize with insulin to induce hepatic Gck expression. | The Biochemical journal 20090501 |
Interest of the association retinaldehyde/glycolic acid in adult acne. | Journal of the European Academy of Dermatology and Venereology : JEADV 20090501 |
Retinoid metabolism in the small intestine during development of liver cirrhosis. | Journal of gastroenterology and hepatology 20090501 |
Nonadiabatic ab initio dynamics of two models of Schiff base retinal. | The journal of physical chemistry. A 20090423 |
Melanoregulin (MREG) modulates lysosome function in pigment epithelial cells. | The Journal of biological chemistry 20090417 |
In conditions of limited chromophore supply rods entrap 11-cis-retinal leading to loss of cone function and cell death. | Human molecular genetics 20090401 |
Substrate specificity of a recombinant chicken beta-carotene 15,15'-monooxygenase that converts beta-carotene into retinal. | Biotechnology letters 20090301 |
Vitamin A metabolism is impaired in human ovarian cancer. | Gynecologic oncology 20090301 |
Isomerization reactions on single adsorbed molecules. | Accounts of chemical research 20090217 |
Complex thermal behavior of 11-cis-retinal, the ligand of the visual pigments. | The Journal of organic chemistry 20090206 |
Helix movement is coupled to displacement of the second extracellular loop in rhodopsin activation. | Nature structural & molecular biology 20090201 |
Photochemical reaction dynamics of the primary event of vision studied by means of a hybrid molecular simulation. | Biophysical journal 20090121 |
Molecular determinants for the stereospecific reduction of 3-ketosteroids and reactivity towards all-trans-retinal of a short-chain dehydrogenase/reductase (DHRS4). | Archives of biochemistry and biophysics 20090115 |
Bicycle-pedal isomerization in a rhodopsin chromophore model. | Journal of the American Chemical Society 20090114 |
A ligand channel through the G protein coupled receptor opsin. | PloS one 20090101 |
Proceedings of the 13th International Conference on Retinal Proteins. Barcelona, Spain. June 15-19, 2008. | Photochemistry and photobiology 20090101 |
Retinal conformation and dynamics in activation of rhodopsin illuminated by solid-state H NMR spectroscopy. | Photochemistry and photobiology 20090101 |
Structural coupling of 11-cis-7-methyl-retinal and amino acids at the ligand binding pocket of rhodopsin. | Photochemistry and photobiology 20090101 |
Release of 11-cis-retinal from cellular retinaldehyde-binding protein by acidic lipids. | Molecular vision 20090101 |
[Studies on the conformational state of the chromophore group (11-cis-retinal) in rhodopsin by computer molecular simulation methods]. | Biofizika 20090101 |
9-Demethylrhodopsin: theoretical evidence for a relaxed batho intermediate. | Biochemistry 20081230 |
Cell imaging: Light activated. | Nature 20081211 |
Koniocellular projections and hand-assisted blindsight. | Neuropsychologia 20081201 |
Night blindness and the mechanism of constitutive signaling of mutant G90D rhodopsin. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20081105 |
Oxidation of PAH trans-dihydrodiols by human aldo-keto reductase AKR1B10. | Chemical research in toxicology 20081101 |
Agonist-induced conformational changes in bovine rhodopsin: insight into activation of G-protein-coupled receptors. | Journal of molecular biology 20081003 |
Retinopathy in mice induced by disrupted all-trans-retinal clearance. | The Journal of biological chemistry 20080926 |
Crystal structure of opsin in its G-protein-interacting conformation. | Nature 20080925 |
Retinyl ester homeostasis in the adipose differentiation-related protein-deficient retina. | The Journal of biological chemistry 20080905 |
Reprogramming progeny cells of embryonic RPE to produce photoreceptors: development of advanced photoreceptor traits under the induction of neuroD. | Investigative ophthalmology & visual science 20080901 |
Excitation energy-transfer and the relative orientation of retinal and carotenoid in xanthorhodopsin. | Biophysical journal 20080901 |
[The participation of dehydrogenases in retinol metabolism]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20080901 |
Applications of natural orbitals for chemical valence in a description of bonding in conjugated molecules. | Journal of molecular modeling 20080801 |
The molecular structure of a curl-shaped retinal isomer. | Journal of molecular modeling 20080801 |
Retinal models: comparison of electronic absorption spectra in the gas phase and in methanol solution. | The journal of physical chemistry. B 20080724 |
Kinetic analysis of human enzyme RDH10 defines the characteristics of a physiologically relevant retinol dehydrogenase. | The Journal of biological chemistry 20080718 |
Mechanism of signal propagation upon retinal isomerization: insights from molecular dynamics simulations of rhodopsin restrained by normal modes. | Biophysical journal 20080715 |
11-cis- and all-trans-retinols can activate rod opsin: rational design of the visual cycle. | Biochemistry 20080715 |
Retinal pigment epithelium-retinal G protein receptor-opsin mediates light-dependent translocation of all-trans-retinyl esters for synthesis of visual chromophore in retinal pigment epithelial cells. | The Journal of biological chemistry 20080711 |
Crystal structure of the ligand-free G-protein-coupled receptor opsin. | Nature 20080710 |
HPLC/UV quantitation of retinal, retinol, and retinyl esters in serum and tissues. | Analytical biochemistry 20080701 |
Crystal structures of substrate-free and retinoic acid-bound cyanobacterial cytochrome P450 CYP120A1. | Biochemistry 20080624 |
Expanding GPCR homology model binding sites via a balloon potential: A molecular dynamics refinement approach. | Proteins 20080601 |
Rpe65-/- and Lrat-/- mice: comparable models of leber congenital amaurosis. | Investigative ophthalmology & visual science 20080601 |
Effect of lipid peroxidation products on the activity of human retinol dehydrogenase 12 (RDH12) and retinoid metabolism. | Biochimica et biophysica acta 20080601 |
Screening and characterization of proteorhodopsin color-tuning mutations in Escherichia coli with endogenous retinal synthesis. | Biochimica et biophysica acta 20080601 |
Mechanism of photoisomerization of the rhodopsin chromophore. | Biochemistry. Biokhimiia 20080601 |
Crystal structure of squid rhodopsin. | Nature 20080515 |
Metabolic basis of visual cycle inhibition by retinoid and nonretinoid compounds in the vertebrate retina. | The Journal of biological chemistry 20080411 |
Trafficking of membrane-associated proteins to cone photoreceptor outer segments requires the chromophore 11-cis-retinal. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20080409 |
Metabolism and biological activities of topical 4-oxoretinoids in mouse skin. | The Journal of investigative dermatology 20080401 |
Nrl-knockout mice deficient in Rpe65 fail to synthesize 11-cis retinal and cone outer segments. | Investigative ophthalmology & visual science 20080301 |
Rhodopsin and 9-demethyl-retinal analog: effect of a partial agonist on displacement of transmembrane helix 6 in class A G protein-coupled receptors. | The Journal of biological chemistry 20080222 |
Retinoid processing in cone and Müller cell lines. | Experimental eye research 20080201 |
Light damaging action of all-trans-retinal and its derivatives on rhodopsin molecules in the photoreceptor membrane. | Biochemistry. Biokhimiia 20080201 |
R91W mutation in Rpe65 leads to milder early-onset retinal dystrophy due to the generation of low levels of 11-cis-retinal. | Human molecular genetics 20080115 |
Optimized formation of detergent micelles of beta-carotene and retinal production using recombinant human beta,beta-carotene 15,15'-monooxygenase. | Biotechnology progress 20080101 |
Ocular biometry in preterm infants: implications for estimation of retinal illuminance. | Investigative ophthalmology & visual science 20080101 |
A convenient and stereoselective synthesis of 11Z-3,4-didehydroretinal by Horner-Emmons reaction using diphenyl phosphonate. | Chemical & pharmaceutical bulletin 20080101 |
A2E, a pigment of RPE lipofuscin, is generated from the precursor, A2PE by a lysosomal enzyme activity. | Advances in experimental medicine and biology 20080101 |
Alpha-retinals as rhodopsin chromophores--preference for the 9-Z configuration and partial agonist activity. | Photochemistry and photobiology 20080101 |
Rhodopsin regeneration is accelerated via noncovalent 11-cis retinal-opsin complex--a role of retinal binding pocket of opsin. | Photochemistry and photobiology 20080101 |
Chromophore interaction in xanthorhodopsin--retinal dependence of salinixanthin binding. | Photochemistry and photobiology 20080101 |
Activity switches of rhodopsin. | Photochemistry and photobiology 20080101 |
Xanthorhodopsin: a bacteriorhodopsin-like proton pump with a carotenoid antenna. | Biochimica et biophysica acta 20080101 |
[Synthesis of spyropyran derivatives of retinal and study of their interaction with bacterioopsin from Halobacterium salinarum]. | Bioorganicheskaia khimiia 20080101 |
Impairment of A2-rhodopsin regeneration induced by visible (blue) light. | Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20080101 |
Structural basis for the high all-trans-retinaldehyde reductase activity of the tumor marker AKR1B10. | Proceedings of the National Academy of Sciences of the United States of America 20071226 |
Overproduction of bioactive retinoic acid in cells expressing disease-associated mutants of retinol dehydrogenase 12. | The Journal of biological chemistry 20071207 |
Solid-state 2H NMR spectroscopy of retinal proteins in aligned membranes. | Biochimica et biophysica acta 20071201 |
Chromophore switch from 11-cis-dehydroretinal (A2) to 11-cis-retinal (A1) decreases dark noise in salamander red rods. | The Journal of physiology 20071115 |
Mechanism of spectral tuning in green-absorbing proteorhodopsin. | Biochemistry 20071106 |
The dual substrate specificity of aldehyde oxidase 1 for retinal and acetaldehyde and its role in ABCA1 mediated efflux. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20071101 |
[Vitamin A, in the eye of the fat]. | Medecine sciences : M/S 20071101 |
7,8-dihydro retinals outperform the native retinals in conferring photosensitivity to visual opsin. | Journal of the American Chemical Society 20071031 |
An opsin shift in rhodopsin: retinal S0-S1 excitation in protein, in solution, and in the gas phase. | Journal of the American Chemical Society 20071031 |
CNDOL: A fast and reliable method for the calculation of electronic properties of very large systems. Applications to retinal binding pocket in rhodopsin and gas phase porphine. | The Journal of chemical physics 20071014 |
Interpreting ion fluxes to channel arrays in monolayers. | Langmuir : the ACS journal of surfaces and colloids 20071009 |
Effective production of retinal from beta-carotene using recombinant mouse beta-carotene 15,15'-monooxygenase. | Applied microbiology and biotechnology 20071001 |
Evidence for RPE65-independent vision in the cone-dominated zebrafish retina. | The European journal of neuroscience 20071001 |
Optical switches and triggers for the manipulation of ion channels and pores. | Molecular bioSystems 20071001 |
Dynamic structure of retinylidene ligand of rhodopsin probed by molecular simulations. | Journal of molecular biology 20070928 |
Structural analysis and dynamics of retinal chromophore in dark and meta I states of rhodopsin from 2H NMR of aligned membranes. | Journal of molecular biology 20070907 |
The twisted C11=C12 bond of the rhodopsin chromophore--a photochemical hot spot. | Journal of the American Chemical Society 20070905 |
IgG antibody patterns in aqueous humor of patients with primary open angle glaucoma and pseudoexfoliation glaucoma. | Molecular vision 20070905 |
Dark rearing rescues P23H rhodopsin-induced retinal degeneration in a transgenic Xenopus laevis model of retinitis pigmentosa: a chromophore-dependent mechanism characterized by production of N-terminally truncated mutant rhodopsin. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20070822 |
Compensated adiabatic inversion pulses: broadband INEPT and HSQC. | Journal of magnetic resonance (San Diego, Calif. : 1997) 20070801 |
Comment on 'Coherent control of retinal isomerization in bacteriorhodopsin'. | Science (New York, N.Y.) 20070727 |
Analysis of the NADH-dependent retinaldehyde reductase activity of amphioxus retinol dehydrogenase enzymes enhances our understanding of the evolution of the retinol dehydrogenase family. | The FEBS journal 20070701 |
[The change of the level of the vascular endothelial growth factor in aqueous humor of patients with neovascular glaucoma before and after anterior retinal cryotherapy]. | [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20070701 |
Electron microscopy: molecular freeze frame. | Nature nanotechnology 20070701 |
Imaging the dynamic behaviour of individual retinal chromophores confined inside carbon nanotubes. | Nature nanotechnology 20070701 |
Direct observation of protein motion during the photochemical reaction cycle of bacteriorhodopsin. | Langmuir : the ACS journal of surfaces and colloids 20070619 |
Cantilever-based sensor for the detection of different chromophore isomers. | Analytical chemistry 20070615 |
Upregulation of thioredoxin system via Nrf2-antioxidant responsive element pathway in adaptive-retinal neuroprotection in vivo and in vitro. | Free radical biology & medicine 20070615 |
Coupled-cluster studies of the lowest excited states of the 11-cis-retinal chromophore. | Physical chemistry chemical physics : PCCP 20070614 |
Chromophore channeling in the G-protein coupled receptor rhodopsin. | Journal of the American Chemical Society 20070606 |
Androgen regulation of aldehyde dehydrogenase 1A3 (ALDH1A3) in the androgen-responsive human prostate cancer cell line LNCaP. | Experimental biology and medicine (Maywood, N.J.) 20070601 |
Retinaldehyde represses adipogenesis and diet-induced obesity. | Nature medicine 20070601 |
Retinaldehyde: more than meets the eye. | Nature medicine 20070601 |
The effects of copper and benzo[a]pyrene on retinoids and reproduction in zebrafish. | Aquatic toxicology (Amsterdam, Netherlands) 20070531 |
Probing the sub-microsecond photodissociation dynamics in gas-phase retinal chromophores. | The journal of physical chemistry. A 20070531 |
Photoisomerization efficiency in UV-absorbing visual pigments: protein-directed isomerization of an unprotonated retinal Schiff base. | Biochemistry 20070529 |
Protein design: reengineering cellular retinoic acid binding protein II into a rhodopsin protein mimic. | Journal of the American Chemical Society 20070516 |
FTIR study of the retinal Schiff base and internal water molecules of proteorhodopsin. | Biochemistry 20070508 |
Beyond retinotopic mapping: the spatial representation of objects in the human lateral occipital complex. | Cerebral cortex (New York, N.Y. : 1991) 20070501 |
Cellular sites of Drosophila NinaB and NinaD activity in vitamin A metabolism. | Molecular and cellular neurosciences 20070501 |
Channelrhodopsin-2-assisted circuit mapping of long-range callosal projections. | Nature neuroscience 20070501 |
Dissection of the pathway required for generation of vitamin A and for Drosophila phototransduction. | The Journal of cell biology 20070423 |
Photochemistry of visual pigment chromophore models by ab initio molecular dynamics. | The journal of physical chemistry. B 20070412 |
Deactivation and proton transfer in light-induced metarhodopsin II/metarhodopsin III conversion: a time-resolved fourier transform infrared spectroscopic study. | The Journal of biological chemistry 20070406 |
Retinal biosynthesis in fungi: characterization of the carotenoid oxygenase CarX from Fusarium fujikuroi. | Eukaryotic cell 20070401 |
Interactions of human serum albumin with retinoic acid, retinal and retinyl acetate. | Biochemical pharmacology 20070315 |
Quantification of sudden light-induced polarization in bacteriorhodopsin by optical rectification. | The journal of physical chemistry. B 20070315 |
Identification of 3-deoxyglucosone dehydrogenase as aldehyde dehydrogenase 1A1 (retinaldehyde dehydrogenase 1). | Biochimie 20070301 |
How a small change in retinal leads to G-protein activation: initial events suggested by molecular dynamics calculations. | Proteins 20070215 |
Involvement of alcohol and aldehyde dehydrogenase activities on hepatic retinoid metabolism and its possible participation in the progression of rat liver regeneration. | Biochemical pharmacology 20070215 |
Solid-state NMR studies of two backbone conformations at Tyr185 as a function of retinal configurations in the dark, light, and pressure adapted bacteriorhodopsins. | Journal of the American Chemical Society 20070207 |
Structural changes in the L photointermediate of bacteriorhodopsin. | Journal of molecular biology 20070202 |
G-protein-coupled receptor signalling through protein networks. | Biochemical Society transactions 20070201 |
RPE65 is essential for the function of cone photoreceptors in NRL-deficient mice. | Investigative ophthalmology & visual science 20070201 |
Sequestration of retinyl esters is essential for retinoid signaling in the zebrafish embryo. | The Journal of biological chemistry 20070112 |
The role of the beta-ionone ring in the photochemical reaction of rhodopsin. | The journal of physical chemistry. A 20070111 |
Photoisomerization in proteorhodopsin mutant D97N. | Photochemistry and photobiology 20070101 |
Tryptophan 171 in Pharaonis phoborhodopsin (sensory rhodopsin II) interacts with the chromophore retinal and its substitution with alanine or threonine slowed down the decay of M- and O-intermediate. | Photochemistry and photobiology 20070101 |
Pressure-induced isomerization of retinal on bacteriorhodopsin as disclosed by fast magic angle spinning NMR. | Photochemistry and photobiology 20070101 |
Sub-5-fs real-time spectroscopy of transition states in bacteriorhodopsin during retinal isomerization. | Photochemistry and photobiology 20070101 |
Light induces programmed cell death by activating multiple independent proteases in a cone photoreceptor cell line. | Investigative ophthalmology & visual science 20070101 |
Combined 0.1% retinaldehyde/ 6% glycolic acid cream in prophylaxis and treatment of acne scarring. | Dermatology (Basel, Switzerland) 20070101 |
Coupling of protonation switches during rhodopsin activation. | Photochemistry and photobiology 20070101 |
Clay mimics color tuning in visual pigments. | Angewandte Chemie (International ed. in English) 20070101 |
Substitution of Pro206 and Ser86 residues in the retinal binding pocket of Anabaena sensory rhodopsin is not sufficient for proton pumping function. | Journal of microbiology and biotechnology 20070101 |
Conformational coupling between the cytoplasmic carboxylic acid and the retinal in a fungal light-driven proton pump. | Biochemistry 20061226 |
Predisposition of the dark state of rhodopsin to functional changes in structure. | Proteins 20061201 |
A methyl group at C7 of 11-cis-retinal allows chromophore formation but affects rhodopsin activation. | Vision research 20061201 |
Arrestin can act as a regulator of rhodopsin photochemistry. | Vision research 20061201 |
Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. | Clinical interventions in aging 20061201 |
The photochemical reaction cycle of retinal reconstituted bacteriorhodopsin. | Journal of photochemistry and photobiology. B, Biology 20061101 |
The role of the 11-cis-retinal ring methyl substituents in visual pigment formation. | Chembiochem : a European journal of chemical biology 20061101 |
Macular degeneration: recent advances and therapeutic opportunities. | Nature reviews. Neuroscience 20061101 |
Quantum chemical study of electronic and structural properties of retinal and some aromatic analogs. | The Journal of chemical physics 20061014 |
Excited-state properties and environmental effects for protonated schiff bases: a theoretical study. | Chemphyschem : a European journal of chemical physics and physical chemistry 20061013 |
Methyl substituents at the 11 or 12 position of retinal profoundly and differentially affect photochemistry and signalling activity of rhodopsin. | Journal of molecular biology 20061013 |
Assignment of the hydrogen-out-of-plane and -in-plane vibrations of the retinal chromophore in the K intermediate of pharaonis phoborhodopsin. | Biochemistry 20061003 |
Propagating structural perturbation inside bacteriorhodopsin: crystal structures of the M state and the D96A and T46V mutants. | Biochemistry 20061003 |
Effect of light exposure on the accumulation and depletion of retinyl ester in the chicken retina. | Experimental eye research 20061001 |
Do we live in a quantum world? Advances in multidimensional coherent spectroscopies refine our understanding of quantum coherences and structural dynamics of biological systems. | Current opinion in structural biology 20061001 |
Improvement in rod and cone function in mouse model of Fundus albipunctatus after pharmacologic treatment with 9-cis-retinal. | Investigative ophthalmology & visual science 20061001 |
Retinal is formed from apo-carotenoids in Nostoc sp. PCC7120: in vitro characterization of an apo-carotenoid oxygenase. | The Biochemical journal 20060915 |
Solvent effects on the low-lying excited states of a model of retinal. | The journal of physical chemistry. B 20060914 |
Induced chirality of the light-harvesting carotenoid salinixanthin and its interaction with the retinal of xanthorhodopsin. | Biochemistry 20060912 |
Chemistry. Controlling biological functions. | Science (New York, N.Y.) 20060901 |
Coherent control of retinal isomerization in bacteriorhodopsin. | Science (New York, N.Y.) 20060901 |
Exploring the molecular mechanism for color distinction in humans. | The journal of physical chemistry. B 20060831 |
Solid-state 2H NMR structure of retinal in metarhodopsin I. | Journal of the American Chemical Society 20060830 |
Autosomal recessive retinitis pigmentosa and E150K mutation in the opsin gene. | The Journal of biological chemistry 20060804 |
Impacts of two point mutations of RPE65 from Leber's congenital amaurosis on the stability, subcellular localization and isomerohydrolase activity of RPE65. | FEBS letters 20060724 |
A novel cytochrome P450, zebrafish Cyp26D1, is involved in metabolism of all-trans retinoic acid. | Molecular endocrinology (Baltimore, Md.) 20060701 |
First steps of retinal photoisomerization in proteorhodopsin. | Biophysical journal 20060701 |
Ground and excited states of retinal schiff base chromophores by multiconfigurational perturbation theory. | Biophysical journal 20060701 |
Effects of quinones and flavonoids on the reduction of all-trans retinal to all-trans retinol in pig heart. | European journal of pharmacology 20060701 |
Bacteriorhodopsin chimeras containing the third cytoplasmic loop of bovine rhodopsin activate transducin for GTP/GDP exchange. | Protein science : a publication of the Protein Society 20060701 |
Heterogeneity in regeneration of bacteriorhodopsin from bacterio-opsin and all-trans retinal at high temperatures: implications for dynamic structural fluctuations. | Bioscience, biotechnology, and biochemistry 20060601 |
Recombination reaction of rhodopsin in situ studied by photoconversion of 'indicator yellow'. | Vision research 20060501 |
Novel retinylidene iminium salts for defining opsin shifts: synthesis and intrinsic chromophoric properties. | Organic & biomolecular chemistry 20060421 |
Conformational change of bacteriorhodopsin quantitatively monitored by microcantilever sensors. | Biophysical journal 20060415 |
FTIR study of the photoisomerization processes in the 13-cis and all-trans forms of Anabaena sensory rhodopsin at 77 K. | Biochemistry 20060411 |
Dynamics of arrestin-rhodopsin interactions: acidic phospholipids enable binding of arrestin to purified rhodopsin in detergent. | The Journal of biological chemistry 20060407 |
The role of Drosophila ninaG oxidoreductase in visual pigment chromophore biogenesis. | The Journal of biological chemistry 20060407 |
Location of Trp265 in metarhodopsin II: implications for the activation mechanism of the visual receptor rhodopsin. | Journal of molecular biology 20060317 |
Molecular evolution of adrenoceptors and dopamine receptors: implications for the binding of catecholamines. | Journal of medicinal chemistry 20060309 |
Neuroglobin and cytoglobin: oxygen-binding proteins in retinal neurons. | Investigative ophthalmology & visual science 20060301 |
RPE65 gene delivery restores isomerohydrolase activity and prevents early cone loss in Rpe65-/- mice. | Investigative ophthalmology & visual science 20060301 |
Uncompetitive inhibition of Xenopus laevis aldehyde dehydrogenase 1A1 by divalent cations. | Zoological science 20060301 |
Agonists and partial agonists of rhodopsin: retinal polyene methylation affects receptor activation. | Biochemistry 20060214 |
Illuminated rhodopsin is required for strong activation of retinal guanylate cyclase by guanylate cyclase-activating proteins. | Biochemistry 20060214 |
Circular dichroism of heterochromophoric and partially regenerated purple membrane: search for exciton coupling. | Chirality 20060201 |
Computation of vertical excitation energies of retinal and analogs: scope and limitations. | Journal of computational chemistry 20060115 |
S1 and S2 excited States of gas-phase Schiff-base retinal chromophores. | Physical review letters 20060113 |
Constitutive activity of a UV cone opsin. | FEBS letters 20060109 |
Synthesis of enantiopure C3- and C4-hydroxyretinals and their enzymatic reduction by ADH8 from Xenopus laevis. | Organic & biomolecular chemistry 20060107 |
Acetaldehyde inhibits the formation of retinoic acid from retinal in the rat esophagus. | Scandinavian journal of gastroenterology 20060101 |
Letter: radical ion and protonated molecule formation with retinal in electrospray and nanospray. | European journal of mass spectrometry (Chichester, England) 20060101 |
Scaffold proteins and the regeneration of visual pigments. | Photochemistry and photobiology 20060101 |
9-cis Retinal increased in retina of RPE65 knockout mice with decrease in coat pigmentation. | Photochemistry and photobiology 20060101 |
UVA and UVB decrease the expression of CD44 and hyaluronate in mouse epidermis, which is counteracted by topical retinoids. | Photochemistry and photobiology 20060101 |
[Photochemical properties of a bacteriorhodopsin analogue containing 13-desmethyl-13-(trifluoromethyl)retinal]. | Biofizika 20060101 |
Computational photochemistry of retinal proteins. | Journal of computer-aided molecular design 20060101 |
Design of an ultrasonic micro-array for near field sensing during retinal microsurgery. | Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 20060101 |
Retinal degeneration associated with RDH12 mutations results from decreased 11-cis retinal synthesis due to disruption of the visual cycle. | Human molecular genetics 20051215 |
Electrostatic potential at the retinal of three archaeal rhodopsins: implications for their different absorption spectra. | Proteins 20051201 |
Steric constraint in the primary photoproduct of an archaeal rhodopsin from regiospecific perturbation of C-D stretching vibration of the retinyl chromophore. | Journal of the American Chemical Society 20051123 |
Chemistry. Following the flow of energy in biomolecules. | Science (New York, N.Y.) 20051111 |
Structural observation of the primary isomerization in vision with femtosecond-stimulated Raman. | Science (New York, N.Y.) 20051111 |
Structural insights into the cellular retinaldehyde-binding protein (CRALBP). | Proteins 20051101 |
Synthesis of N-heteroaryl retinals and their artificial bacteriorhodopsins. | Chembiochem : a European journal of chemical biology 20051101 |
Partial agonism in a G Protein-coupled receptor: role of the retinal ring structure in rhodopsin activation. | The Journal of biological chemistry 20051007 |
Opsin activation of transduction in the rods of dark-reared Rpe65 knockout mice. | The Journal of physiology 20051001 |
Cone opsin mislocalization in Rpe65-/- mice: a defect that can be corrected by 11-cis retinal. | Investigative ophthalmology & visual science 20051001 |
Efficiency of a few retinoids and carotenoids in vivo in controlling benzo[a]pyrene-induced forestomach tumour in female Swiss mice. | The British journal of nutrition 20051001 |
Molecular dynamics simulations of retinal in rhodopsin: from the dark-adapted state towards lumirhodopsin. | Biochemistry 20050927 |
Xanthorhodopsin: a proton pump with a light-harvesting carotenoid antenna. | Science (New York, N.Y.) 20050923 |
Mutation of key residues of RPE65 abolishes its enzymatic role as isomerohydrolase in the visual cycle. | Proceedings of the National Academy of Sciences of the United States of America 20050920 |
Crystal structure of the 13-cis isomer of bacteriorhodopsin in the dark-adapted state. | Journal of molecular biology 20050916 |
Absorption of schiff-base retinal chromophores in vacuo. | Journal of the American Chemical Society 20050907 |
Agonists and partial agonists of rhodopsin: retinals with ring modifications. | Biochemistry 20050906 |
Expression of keratinocyte transglutaminase in cornea of vitamin A-deficient rats. | Current eye research 20050901 |
The retinal G protein-coupled receptor (RGR) enhances isomerohydrolase activity independent of light. | The Journal of biological chemistry 20050819 |
Involvement of carbonyl reductase in superoxide formation through redox cycling of adrenochrome and 9,10-phenanthrenequinone in pig heart. | Chemico-biological interactions 20050815 |
A tiny excited-state barrier can induce a multiexponential decay of the retinal chromophore: a quantum dynamics investigation. | Angewandte Chemie (International ed. in English) 20050812 |
Tuning of retinal twisting in bacteriorhodopsin controls the directionality of the early photocycle steps. | The journal of physical chemistry. B 20050811 |
Probing the ultrafast charge translocation of photoexcited retinal in bacteriorhodopsin. | Science (New York, N.Y.) 20050805 |
Mole quantity of RPE65 and its productivity in the generation of 11-cis-retinal from retinyl esters in the living mouse eye. | Biochemistry 20050726 |
Intrinsically photosensitive retinal ganglion cells detect light with a vitamin A-based photopigment, melanopsin. | Proceedings of the National Academy of Sciences of the United States of America 20050719 |
Breaking the covalent bond--a pigment property that contributes to desensitization in cones. | Neuron 20050616 |
Titration of the bacteriorhodopsin Schiff base involves titration of an additional protein residue. | Biochemistry 20050614 |
FTIR studies of the photoactivation processes in squid retinochrome. | Biochemistry 20050607 |
Novel mutation in RLBP1 gene in a Japanese patient with retinitis punctata albescens. | American journal of ophthalmology 20050601 |
[Gene clone and sequence analysis of retinal specific rho promoter]. | Yan ke xue bao = Eye science 20050601 |
Role of photoreceptor-specific retinol dehydrogenase in the retinoid cycle in vivo. | The Journal of biological chemistry 20050513 |
Biochemical properties of purified human retinol dehydrogenase 12 (RDH12): catalytic efficiency toward retinoids and C9 aldehydes and effects of cellular retinol-binding protein type I (CRBPI) and cellular retinaldehyde-binding protein (CRALBP) on the oxidation and reduction of retinoids. | Biochemistry 20050510 |
Exploring the potential energy surface of retinal, a comparison of the performance of different methods. | Journal of computational chemistry 20050501 |
Vitamin a deficiency in patients with common variable immunodeficiency. | Journal of clinical immunology 20050501 |
Selective interface detection: mapping binding site contacts in membrane proteins by NMR spectroscopy. | Journal of the American Chemical Society 20050427 |
Photochromicity of Anabaena sensory rhodopsin, an atypical microbial receptor with a cis-retinal light-adapted form. | The Journal of biological chemistry 20050415 |
The structure of a retinal-forming carotenoid oxygenase. | Science (New York, N.Y.) 20050408 |
Downregulation of cone-specific gene expression and degeneration of cone photoreceptors in the Rpe65-/- mouse at early ages. | Investigative ophthalmology & visual science 20050401 |
Ultrafast excited state dynamics of the protonated Schiff base of all-trans retinal in solvents. | Biophysical journal 20050401 |
The Drosophila ninaG oxidoreductase acts in visual pigment chromophore production. | The Journal of biological chemistry 20050325 |
Calculating absorption shifts for retinal proteins: computational challenges. | The journal of physical chemistry. B 20050303 |
Photoisomerization mechanism of 11-cis-locked artificial retinal chromophores: acceleration and primary photoproduct assignment. | Journal of the American Chemical Society 20050302 |
Reduction of all-trans retinal to all-trans retinol in the outer segments of frog and mouse rod photoreceptors. | Biophysical journal 20050301 |
Restored epidermal CD44 expression in lichen sclerosus et atrophicus and clinical improvement with topical application of retinaldehyde. | The British journal of dermatology 20050301 |
Retinal degeneration 12 (rd12): a new, spontaneously arising mouse model for human Leber congenital amaurosis (LCA). | Molecular vision 20050227 |
Dynamics of arrestin-rhodopsin interactions: arrestin and retinal release are directly linked events. | The Journal of biological chemistry 20050225 |
Addition of human melanopsin renders mammalian cells photoresponsive. | Nature 20050217 |
Neurobiology: bright blue times. | Nature 20050217 |
Water dynamics simulation as a tool for probing proton transfer pathways in a heptahelical membrane protein. | Proteins 20050215 |
pH-dependent photoisomerization of retinal in proteorhodopsin. | Biochemistry 20050215 |
Amino acid residues responsible for the meta-III decay rates in rod and cone visual pigments. | Biochemistry 20050215 |
Cis-retinol dehydrogenase: 9-cis-retinol metabolism and its effect on proliferation of human MCF7 breast cancer cells. | Experimental cell research 20050201 |
[Function of bestrophin]. | Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20050201 |
Retinal biosynthesis in Eubacteria: in vitro characterization of a novel carotenoid oxygenase from Synechocystis sp. PCC 6803. | Molecular microbiology 20050201 |
Illumination of the melanopsin signaling pathway. | Science (New York, N.Y.) 20050128 |
A dark and constitutively active mutant of the tiger salamander UV pigment. | Biochemistry 20050118 |
High-field EPR spectroscopy applied to biological systems: characterization of molecular switches for electron and ion transfer. | Physical chemistry chemical physics : PCCP 20050107 |
Accurate CSA measurements from uniformly isotopically labeled biomolecules at high magnetic field. | Journal of magnetic resonance (San Diego, Calif. : 1997) 20050101 |
Regeneration of bacteriorhodopsin from thermally unfolded bacterio-opsin and all-trans retinal at high temperatures. | Bioscience, biotechnology, and biochemistry 20050101 |
Retinoid metabolism in the rat small intestine. | The British journal of nutrition 20050101 |
Mixing glycolic acid with retinaldehyde: RALGA, a technical achievement. | Dermatology (Basel, Switzerland) 20050101 |
Pharmacology of RALGA, a mixture of retinaldehyde and glycolic acid. | Dermatology (Basel, Switzerland) 20050101 |
Efficacy and safety of 0.1% retinaldehyde/ 6% glycolic acid (diacneal) for mild to moderate acne vulgaris. A multicentre, double-blind, randomized, vehicle-controlled trial. | Dermatology (Basel, Switzerland) 20050101 |
Topical retinaldehyde with glycolic acid: study of tolerance and acceptability in association with anti-acne treatments in 1,709 patients. | Dermatology (Basel, Switzerland) 20050101 |
The depigmenting effect of RALGA in C57BL/6 mice. | Dermatology (Basel, Switzerland) 20050101 |
RALGA (Diacneal) decreases melanin content in a human skin model. | Dermatology (Basel, Switzerland) 20050101 |
RALGA (Diacneal), a retinaldehyde and glycolic acid association and postinflammatory hyperpigmentation in acne--a review. | Dermatology (Basel, Switzerland) 20050101 |
Partial dehydration of the retinal binding pocket and proof for photochemical deprotonation of the retinal Schiff base in bicelle bacteriorhodopsin crystals. | Photochemistry and photobiology 20050101 |
Light-induced damage to the retina: role of rhodopsin chromophore revisited. | Photochemistry and photobiology 20050101 |
Comparative study of the anti-aging effect of retinaldehyde alone or associated with pretocopheryl in a surviving human skin model submitted to ultraviolet A and B irradiation. | International journal of tissue reactions 20050101 |
N-retinylidene-phosphatidylethanolamine is the preferred retinoid substrate for the photoreceptor-specific ABC transporter ABCA4 (ABCR). | The Journal of biological chemistry 20041224 |
Counterion controlled photoisomerization of retinal chromophore models: a computational investigation. | Journal of the American Chemical Society 20041215 |
Activation and function of mitochondrial uncoupling protein in plants. | The Journal of biological chemistry 20041210 |
Effect of vitamin A depletion on nonvisual phototransduction pathways in cryptochromeless mice. | Journal of biological rhythms 20041201 |
A molecular spring for vision. | Journal of the American Chemical Society 20041201 |
Retinal is the essential form of retinoid for storage and transport in the adult of the ascidian Halocynthia roretzi. | Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20041201 |
Constraints of the 9-methyl group binding pocket of the rhodopsin chromophore probed by 9-halogeno substitution. | Biochemistry 20041123 |
Synthesis of ring-oxidized retinoids as substrates of mouse class I alcohol dehydrogenase (ADH1). | Organic & biomolecular chemistry 20041121 |
Transition of rhodopsin into the active metarhodopsin II state opens a new light-induced pathway linked to Schiff base isomerization. | The Journal of biological chemistry 20041112 |
Key role of electrostatic interactions in bacteriorhodopsin proton transfer. | Journal of the American Chemical Society 20041110 |
Patterns of retinal light absorption related to retinitis pigmentosa mutants from in silico model structures of rhodopsin. | Proteins 20041101 |
Absolute configurational determination of an all-trans-retinal dimer isolated from photoreceptor outer segments. | Chirality 20041101 |
TD-DFT calculations of the potential energy curves for the trans-cis photo-isomerization of protonated Schiff base of retinal. | Journal of photochemistry and photobiology. B, Biology 20041025 |
Deuterium NMR structure of retinal in the ground state of rhodopsin. | Biochemistry 20041012 |
Vitamin A exhibits potent antiamyloidogenic and fibril-destabilizing effects in vitro. | Experimental neurology 20041001 |
The retinal conformation and its environment in rhodopsin in light of a new 2.2 A crystal structure. | Journal of molecular biology 20040910 |
Different SAR86 subgroups harbour divergent proteorhodopsins. | Environmental microbiology 20040901 |
Support for a proposed retinoid-processing protein complex in apical retinal pigment epithelium. | Experimental eye research 20040901 |
The quantum topological electrostatic potential as a probe for functional group transferability. | Acta crystallographica. Section A, Foundations of crystallography 20040901 |
FTIR spectroscopy of the K photointermediate of Neurospora rhodopsin: structural changes of the retinal, protein, and water molecules after photoisomerization. | Biochemistry 20040803 |
Impact of noise on retinal coding of visual signals. | Journal of neurophysiology 20040801 |
[Visual cycle and dark adaptation: a new approach in research]. | Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20040801 |
What is the real crystallographic structure of the L photointermediate of bacteriorhodopsin? | Biochimica et biophysica acta 20040723 |
Toward the active conformations of rhodopsin and the beta2-adrenergic receptor. | Proteins 20040701 |
A novel compound heterozygous mutation in the cellular retinaldehyde-binding protein gene (RLBP1) in a patient with retinitis punctata albescens. | American journal of ophthalmology 20040701 |
The visual cycle of the cone photoreceptors of the retina. | Nutrition reviews 20040701 |
Identification of CRALBP ligand interactions by photoaffinity labeling, hydrogen/deuterium exchange, and structural modeling. | The Journal of biological chemistry 20040625 |
Femtosecond primary events in bacteriorhodopsin and its retinal modified analogs: revision of commonly accepted interpretation of electronic spectra of transient intermediates in the bacteriorhodopsin photocycle. | The Journal of chemical physics 20040615 |
A palmitoylation switch mechanism in the regulation of the visual cycle. | Cell 20040611 |
FTIR spectroscopy of the O photointermediate in pharaonis phoborhodopsin. | Biochemistry 20040511 |
Role of the 9-methyl group of retinal in cone visual pigments. | Biochemistry 20040511 |
In vivo treatment with CPT-11 leads to differentiation of neuroblastoma xenografts and topoisomerase I alterations. | Cancer research 20040501 |
Ultrasound imaging demonstration of the improvement of non-ablative laser remodeling by concomitant daily topical application of 0.05% retinaldehyde. | Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology 20040501 |
Drosophila ninaB and ninaD act outside of retina to produce rhodopsin chromophore. | The Journal of biological chemistry 20040430 |
Effect of beta-particles on the retinal chromophore in bacteriorhodopsin of Halobacterium salinarium. | Radiation measurements 20040401 |
Impairment of the transient pupillary light reflex in Rpe65(-/-) mice and humans with leber congenital amaurosis. | Investigative ophthalmology & visual science 20040401 |
[The frosted retinal vascular branch syndrome]. | Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti 20040401 |
Light adaptation of bacteriorhodopsin correlates with dielectric spectral kinetics in purple membrane. | Biochemical and biophysical research communications 20040319 |
The nitrate transporting photochemical reaction cycle of the pharaonis halorhodopsin. | Biophysical journal 20040301 |
A purified agonist-activated G-protein coupled receptor: truncated octopus Acid Metarhodopsin. | Zoological science 20040301 |
Induction of 1,N(2)-etheno-2'-deoxyguanosine in DNA exposed to beta-carotene oxidation products. | FEBS letters 20040227 |
Selectivity of retinal photoisomerization in proteorhodopsin is controlled by aspartic acid 227. | Biochemistry 20040217 |
Cellular retinaldehyde-binding protein interacts with ERM-binding phosphoprotein 50 in retinal pigment epithelium. | Investigative ophthalmology & visual science 20040201 |
Crystal structure of the L intermediate of bacteriorhodopsin: evidence for vertical translocation of a water molecule during the proton pumping cycle. | Journal of molecular biology 20040109 |
Novel mutations in the cellular retinaldehyde-binding protein gene (RLBP1) associated with retinitis punctata albescens: evidence of interfamilial genetic heterogeneity and fundus changes in heterozygotes. | Archives of ophthalmology (Chicago, Ill. : 1960) 20040101 |
Isotretinoin treatment inhibits lipofuscin accumulation in a mouse model of recessive Stargardt's macular degeneration. | Novartis Foundation symposium 20040101 |
Primary events in dim light vision: a chemical and spectroscopic approach toward understanding protein/chromophore interactions in rhodopsin. | Chemical record (New York, N.Y.) 20040101 |
Interaction of class A G protein-coupled receptors with G proteins. | Acta biochimica Polonica 20040101 |
X-ray diffraction of bacteriorhodopsin photocycle intermediates. | Molecular membrane biology 20040101 |
Second harmonic imaging of membrane potential of neurons with retinal. | Journal of biomedical optics 20040101 |
Retinaldehyde, a potent inhibitor of gap junctional intercellular communication. | Cell communication & adhesion 20040101 |
Positive, accurate animal identification. | Animal reproduction science 20031215 |
(9Z)- and (11Z)-8-methylretinals for artificial visual pigment studies: stereoselective synthesis, structure, and binding models. | Chemistry (Weinheim an der Bergstrasse, Germany) 20031205 |
Human requirements for fat-soluble vitamins, and other things concerning these nutrients. | Molecular aspects of medicine 20031201 |
Retinoid cycle in the vertebrate retina: experimental approaches and mechanisms of isomerization. | Vision research 20031201 |
A2E, a byproduct of the visual cycle. | Vision research 20031201 |
Secondary binding sites of retinoids in opsin: characterization and role in regeneration. | Vision research 20031201 |
Bleaching desensitization: background and current challenges. | Vision research 20031201 |
Interphotoreceptor retinoid-binding protein--an old gene for new eyes. | Vision research 20031201 |
Availability of 11-cis retinal and opsins without chromophore as revealed by small bleaches of rhodopsin in excised albino mouse eyes. | Vision research 20031201 |
Perceptual efficacy of electrical stimulation of human retina with a microelectrode array during short-term surgical trials. | Investigative ophthalmology & visual science 20031201 |
Specific isomerization of rhodopsin-bound 11-cis-retinal to all-trans-retinal under thermal denaturation. | Cellular and molecular life sciences : CMLS 20031101 |
Excited-state singlet manifold and oscillatory features of a nonatetraeniminium retinal chromophore model. | Journal of the American Chemical Society 20031015 |
Heterogeneity effects in the binding of all-trans retinal to bacterio-opsin. | Biochemistry 20030930 |
Molecular dynamics simulation of bacteriorhodopsin's photoisomerization using ab initio forces for the excited chromophore. | Biophysical journal 20030901 |
A photochemical study of (E,E,E,E)-2-[9-(2-hydroxyethyl)imino-3,7-dimethyl-1,3,5,7-decatrien-1-yl]- 1,3,3-trimethylcyclohexene, a derivative of all-trans-retinal and ethanolamine. | Photochemistry and photobiology 20030901 |
Structural changes of water molecules during the photoactivation processes in bovine rhodopsin. | Biochemistry 20030819 |
Crystallographic structures of the M and N intermediates of bacteriorhodopsin: assembly of a hydrogen-bonded chain of water molecules between Asp-96 and the retinal Schiff base. | Journal of molecular biology 20030711 |
Ligand channeling within a G-protein-coupled receptor. The entry and exit of retinals in native opsin. | The Journal of biological chemistry 20030704 |
Opsin activation as a cause of congenital night blindness. | Nature neuroscience 20030701 |
Probing the rhodopsin cavity with reduced retinal models at the CASPT2//CASSCF/AMBER level of theory. | Journal of the American Chemical Society 20030611 |
Photoexcitation of the O-intermediate in bacteriorhodopsin mutant L93A. | Biophysical journal 20030601 |
Molecular basis of spectral tuning in the newt short wavelength sensitive visual pigment. | Biochemistry 20030527 |
Enzymatic characterization of recombinant mouse retinal dehydrogenase type 1. | Biochemical pharmacology 20030515 |
Provitamin A conversion to retinal via the beta,beta-carotene-15,15'-oxygenase (bcox) is essential for pattern formation and differentiation during zebrafish embryogenesis. | Development (Cambridge, England) 20030501 |
Evaluation of the role of the retinal G protein-coupled receptor (RGR) in the vertebrate retina in vivo. | Journal of neurochemistry 20030501 |
Mechanism of proton transport in bacteriorhodopsin from crystallographic structures of the K, L, M1, M2, and M2' intermediates of the photocycle. | Journal of molecular biology 20030425 |
Reduction of all-trans-retinal in the mouse liver peroxisome fraction by the short-chain dehydrogenase/reductase RRD: induction by the PPAR alpha ligand clofibrate. | Biochemistry 20030415 |
The photoreceptive capacity of the developing pineal gland and eye of the golden hamster (Mesocricetus auratus). | Journal of neuroendocrinology 20030401 |
Acute radiolabeling of retinoids in eye tissues of normal and rpe65-deficient mice. | Investigative ophthalmology & visual science 20030401 |
Decisive role of electronic polarization of the protein environment in determining the absorption maximum of halorhodopsin. | Journal of the American Chemical Society 20030312 |
Relationship between photoisomerization path and intersection space in a retinal chromophore model. | Journal of the American Chemical Society 20030305 |
Demonstration of a sensory rhodopsin in eubacteria. | Molecular microbiology 20030301 |
Comparison of the aerobic photoreactivity of A2E with its precursor retinal. | Photochemistry and photobiology 20030301 |
An opsin mutant with increased thermal stability. | Biochemistry 20030225 |
Slow binding of retinal to rhodopsin mutants G90D and T94D. | Biochemistry 20030225 |
Storage of retinal in the eggs of the ascidian, Halocynthia roretzi. | Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20030201 |
Cloning of monkey RALDH1 and characterization of retinoid metabolism in monkey kidney proximal tubule cells. | Journal of lipid research 20030201 |
Cytosolic retinoid dehydrogenases govern ubiquitous metabolism of retinol to retinaldehyde followed by tissue-specific metabolism to retinoic acid. | Chemico-biological interactions 20030201 |
Signaling states of rhodopsin. Formation of the storage form, metarhodopsin III, from active metarhodopsin II. | The Journal of biological chemistry 20030131 |
Correlation of regenerable opsin with rod ERG signal in Rpe65-/- mice during development and aging. | Investigative ophthalmology & visual science 20030101 |
Fourier transform IR spectroscopy study for new insights into molecular properties and activation mechanisms of visual pigment rhodopsin. | Biopolymers 20030101 |
Visually perceived eye level with reversible pitch stimuli: implications for the great circle and implicit surface models. | Perception 20030101 |
Differential expression of heparin-binding EGF-like growth factor (HB-EGF) mRNA in normal human keratinocytes induced by a variety of natural and synthetic retinoids. | Experimental dermatology 20030101 |
A2E, a fluorophore of RPE lipofuscin: can it cause RPE degeneration? | Advances in experimental medicine and biology 20030101 |
11-cis-retinal protonated Schiff base: influence of the protein environment on the geometry of the rhodopsin chromophore. | Biochemistry 20021224 |
Molecular dynamics investigation of primary photoinduced events in the activation of rhodopsin. | Biophysical journal 20021201 |
Bacteriorhodopsin analog regenerated with 13-desmethyl-13-iodoretinal. | Biophysical journal 20021201 |
Constraints of opsin structure on the ligand-binding site: studies with ring-fused retinals. | Photochemistry and photobiology 20021201 |
Dual-substrate specificity short chain retinol dehydrogenases from the vertebrate retina. | The Journal of biological chemistry 20021122 |
Amphioxus homologs of Go-coupled rhodopsin and peropsin having 11-cis- and all-trans-retinals as their chromophores. | FEBS letters 20021120 |
Biochemical and physiological properties of rhodopsin regenerated with 11-cis-6-ring- and 7-ring-retinals. | The Journal of biological chemistry 20021101 |
Cloning and characterization of a novel all-trans retinol short-chain dehydrogenase/reductase from the RPE. | Investigative ophthalmology & visual science 20021101 |
11-cis-retinal reduces constitutive opsin phosphorylation and improves quantum catch in retinoid-deficient mouse rod photoreceptors. | The Journal of biological chemistry 20021025 |
Rhodopsin with 11-cis-locked chromophore is capable of forming an active state photoproduct. | The Journal of biological chemistry 20021025 |
Bacteriorhodopsin: a high-resolution structural view of vectorial proton transport. | Biochimica et biophysica acta 20021011 |
Structural studies on rhodopsin. | Biochimica et biophysica acta 20021011 |
Structural basis for sensory rhodopsin function. | Biochimica et biophysica acta 20021011 |
Light-induced charge redistribution in the retinal chromophore is required for initiating the bacteriorhodopsin photocycle. | Journal of the American Chemical Society 20021009 |
Crystal structure of rhodopsin: a G-protein-coupled receptor. | Chembiochem : a European journal of chemical biology 20021004 |
Active states of rhodopsin. | Chembiochem : a European journal of chemical biology 20021004 |
Relaxation of beta-structure in tear lipocalin and enhancement of retinoid binding. | Investigative ophthalmology & visual science 20021001 |
Like night and day: rods and cones have different pigment regeneration pathways. | Neuron 20020926 |
Isomerization and oxidation of vitamin a in cone-dominant retinas: a novel pathway for visual-pigment regeneration in daylight. | Neuron 20020926 |
Large-scale morphological survey of mouse retinal ganglion cells. | The Journal of comparative neurology 20020916 |
Early steps of the intramolecular signal transduction in rhodopsin explored by molecular dynamics simulations. | Biochemistry 20020903 |
Recreating a functional ancestral archosaur visual pigment. | Molecular biology and evolution 20020901 |
Selected retinoids: determination by isocratic normal-phase HPLC. | Endocrine regulations 20020901 |
Crystallographic structure of the K intermediate of bacteriorhodopsin: conservation of free energy after photoisomerization of the retinal. | Journal of molecular biology 20020823 |
Crystallographic structure of the retinal and the protein after deprotonation of the Schiff base: the switch in the bacteriorhodopsin photocycle. | Journal of molecular biology 20020823 |
Opsins and melanopsins. | Current biology : CB 20020820 |
Vibrational polarization and opsin shift of retinal schiff bases: theoretical study. | Journal of the American Chemical Society 20020807 |
Femtosecond infrared spectroscopy of bacteriorhodopsin chromophore isomerization. | Science (New York, N.Y.) 20020802 |
Beta-carotene cleavage products induce oxidative stress in vitro by impairing mitochondrial respiration. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020801 |
The cellular fate of mutant rhodopsin: quality control, degradation and aggresome formation. | Journal of cell science 20020715 |
Channelrhodopsin-1: a light-gated proton channel in green algae. | Science (New York, N.Y.) 20020628 |
Solution and biologically relevant conformations of enantiomeric 11-cis-locked cyclopropyl retinals. | Journal of the American Chemical Society 20020626 |
All-trans-retinal shuts down rod cyclic nucleotide-gated ion channels: a novel role for photoreceptor retinoids in the response to bright light? | Proceedings of the National Academy of Sciences of the United States of America 20020611 |
The preparation of all-trans uniformly (13)C-labeled retinal via a modular total organic synthetic strategy. emerging central contribution of organic synthesis toward the structure and function study with atomic resolution in protein research. | Journal of the American Chemical Society 20020605 |
Photoreduction of bacteriorhodopsin Schiff base at low humidity. A study with C13=C14 nonisomerizable artificial pigments. | Photochemistry and photobiology 20020601 |
Proton translocation by bacteriorhodopsin in the absence of substantial conformational changes. | Journal of molecular biology 20020531 |
Recovery of visual functions in a mouse model of Leber congenital amaurosis. | The Journal of biological chemistry 20020524 |
A pharaonis phoborhodopsin mutant with the same retinal binding site residues as in bacteriorhodopsin. | Biochemistry 20020521 |
Recombinant class I aldehyde dehydrogenases specific for all-trans- or 9-cis-retinal. | The Journal of biological chemistry 20020517 |
Synthesis of 11-cis-locked bicyclo[5.1.0]octanyl retinal and an enantioselective binding to bovine opsin. | Chirality 20020505 |
Light-induced hydrolysis and rebinding of nonisomerizable bacteriorhodopsin pigment. | Biophysical journal 20020501 |
Reaction path analysis of the 'tunable' photoisomerization selectivity of free and locked retinal chromophores. | Journal of the American Chemical Society 20020417 |
Interaction of Asn105 with the retinal chromophore during photoisomerization of pharaonis phoborhodopsin. | Biochemistry 20020409 |
Electronic excitations of biomolecules studied by quantum chemistry. | Current opinion in structural biology 20020401 |
All-trans to 13-cis retinal isomerization in light-adapted bacteriorhodopsin at acidic pH. | Journal of photochemistry and photobiology. B, Biology 20020401 |
Effects of light and low oxygen tension on pigment biosynthesis in Halobacterium salinarum, revealed by a novel method to quantify both retinal and carotenoids. | Plant & cell physiology 20020401 |
Kinetic analysis of mouse retinal dehydrogenase type-2 (RALDH2) for retinal substrates. | Biochimica et biophysica acta 20020401 |
Vitamin A-related compounds, all-trans retinal and retinoic acids, selectively inhibit activities of mammalian replicative DNA polymerases. | Biochimica et biophysica acta 20020220 |
Tryptophan interactions in bacteriorhodopsin: a heteronuclear solid-state NMR study. | Biochemistry 20020219 |
Bleaching kinetics of artificial visual pigments with modifications near the ring-polyene chain connection. | Biochemistry 20020212 |
Synthesis of the all-trans-retinal chromophore of retinal G protein-coupled receptor opsin in cultured pigment epithelial cells. | The Journal of biological chemistry 20020201 |
Retinoid composition and retinal localization in the eggs of teleost fishes. | Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20020201 |
Changes in the retinal transition dipole moment in bacteriorhodopsin of the purple membrane of Halobacterium Salinarium at the so-called PH(rev). | Journal of biochemistry, molecular biology, and biophysics : JBMBB : the official journal of the Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB) 20020201 |
Combined QM/MM study of the opsin shift in bacteriorhodopsin. | Journal of computational chemistry 20020115 |
Selective photostimulation of genetically chARGed neurons. | Neuron 20020103 |
Use of retinal analogues for the study of visual pigment function. | Methods in enzymology 20020101 |
The eye as metronome of the body. | Survey of ophthalmology 20020101 |
4-(N,N-dipropylamino)benzaldehyde inhibits the oxidation of all-trans retinal to all-trans retinoic acid by ALDH1A1, but not the differentiation of HL-60 promyelocytic leukemia cells exposed to all-trans retinal. | BMC pharmacology 20020101 |
Designing and characterizing hammerhead ribozymes for use in AAV vector-mediated retinal gene therapies. | Methods in enzymology 20020101 |
Energy transfer from tryptophane amino acid residues to retinal in a bacteriorhodopsin molecule within a femtosecond timescale. | Doklady. Biochemistry and biophysics 20020101 |
A retrospective study of the effect of long-term topical application of retinaldehyde (0.05%) on the development of actinic keratosis. | Dermatology (Basel, Switzerland) 20020101 |
The antibacterial activity of topical retinoids: the case of retinaldehyde. | Dermatology (Basel, Switzerland) 20020101 |
[A convenient synthesis of retinal derivatives with a modified trimethylcyclohexene ring]. | Bioorganicheskaia khimiia 20020101 |
Topical retinaldehyde treatment in oral lichen planus and leukoplakia. | International journal of tissue reactions 20020101 |
Biochemical defects in 11-cis-retinol dehydrogenase mutants associated with fundus albipunctatus. | The Journal of biological chemistry 20011228 |
Environment around the chromophore in pharaonis phoborhodopsin: mutation analysis of the retinal binding site. | Biochimica et biophysica acta 20011201 |
Direction tuning of inhibitory inputs to the turtle accessory optic system. | Journal of neurophysiology 20011201 |
A semiempirical study of the optimized ground and excited state potential energy surfaces of retinal and its protonated Schiff base. | Journal of photochemistry and photobiology. B, Biology 20011201 |
The nature of the delocalized cations in azulenic bacteriorhodopsin analogs. | Photochemistry and photobiology 20011201 |
Real-time spectroscopy of transition states in bacteriorhodopsin during retinal isomerization. | Nature 20011129 |
Regulation of phototransduction in short-wavelength cone visual pigments via the retinylidene Schiff base counterion. | Biochemistry 20011120 |
Wavelength dependent cis-trans isomerization in vision. | Biochemistry 20011120 |
Retinal isomerization in bacteriorhodopsin is controlled by specific chromophore-protein interactions. A study with noncovalent artificial pigments. | Biochemistry 20011106 |
Photoreceptor current and photoorientation in chlamydomonas mediated by 9-demethylchlamyrhodopsin. | Biophysical journal 20011101 |
Effect of Rpe65 knockout on accumulation of lipofuscin fluorophores in the retinal pigment epithelium. | Investigative ophthalmology & visual science 20011101 |
Estimation of carbon-carbon bond lengths and medium-range internuclear distances by solid-state nuclear magnetic resonance. | Journal of the American Chemical Society 20011031 |
Crystal structure of the D85S mutant of bacteriorhodopsin: model of an O-like photocycle intermediate. | Journal of molecular biology 20011026 |
Steric barrier to bathorhodopsin decay in 5-demethyl and mesityl analogues of rhodopsin. | Journal of the American Chemical Society 20011017 |
Metabolism of vitamin A affected by prostaglandin F synthase in contractile interstitial cells of bovine lung. | Biochemical and biophysical research communications 20011005 |
Rhodopsin: structural basis of molecular physiology. | Physiological reviews 20011001 |
Retinoic acid biosynthesis by normal human breast epithelium is via aldehyde dehydrogenase 6, absent in MCF-7 cells. | Cancer research 20011001 |
On the bioactive conformation of the rhodopsin chromophore: absolute sense of twist around the 6-s-cis bond. | Chemistry (Weinheim an der Bergstrasse, Germany) 20011001 |
Coupling of the reisomerization of the retinal, proton uptake, and reprotonation of Asp-96 in the N photointermediate of bacteriorhodopsin. | Biochemistry 20010925 |
Kinetics of photo-active bacteriorhodopsin analog 3,4-didehydroretinal. | Journal of photochemistry and photobiology. B, Biology 20010915 |
Crystal structure of sensory rhodopsin II at 2.4 angstroms: insights into color tuning and transducer interaction. | Science (New York, N.Y.) 20010824 |
Structural changes of pharaonis phoborhodopsin upon photoisomerization of the retinal chromophore: infrared spectral comparison with bacteriorhodopsin. | Biochemistry 20010807 |
The effects of 3,4,3'-triiodo-l-thyronine on didehydroretinol synthesis by isolated coho salmon retinal pigment epithelial cells. | General and comparative endocrinology 20010801 |
Bacteriorhodopsin. | Current opinion in structural biology 20010801 |
Crystal structure of rhodopsin: implications for vision and beyond. | Current opinion in structural biology 20010801 |
Multiple phosphorylation of rhodopsin and the in vivo chemistry underlying rod photoreceptor dark adaptation. | Neuron 20010719 |
A photic visual cycle of rhodopsin regeneration is dependent on Rgr. | Nature genetics 20010701 |
Engineering a functional blue-wavelength-shifted rhodopsin mutant. | Biochemistry 20010619 |
Interaction of 11-cis-retinol dehydrogenase with the chromophore of retinal g protein-coupled receptor opsin. | The Journal of biological chemistry 20010615 |
Simultaneous quantification of retinol, retinal, and retinoic acid isomers by high-performance liquid chromatography with a simple gradiation. | Journal of chromatography. B, Biomedical sciences and applications 20010615 |
Proteorhodopsin phototrophy in the ocean. | Nature 20010614 |
The effect of metal cation binding on the protein, lipid and retinal isomeric ratio in regenerated bacteriorhodopsin of purple membrane. | Photochemistry and photobiology 20010501 |
Standard apparent reduction potentials for biochemical half reactions as a function of pH and ionic strength. | Archives of biochemistry and biophysics 20010501 |
Differential effects of retinoids on proliferation of bovine mammary epithelial cells in collagen gel culture. | The Journal of dairy research 20010501 |
Free radical lipid peroxidation inhibits enzymatic conversion of beta-carotene into vitamin A. | Bulletin of experimental biology and medicine 20010501 |
Identification and characterization of a mammalian enzyme catalyzing the asymmetric oxidative cleavage of provitamin A. | The Journal of biological chemistry 20010427 |
Time-resolved FT-IR spectroscopic investigation of the pH-dependent proton transfer reactions in the E194Q mutant of bacteriorhodopsin. | Biochemical and biophysical research communications 20010427 |
Structure and function in bacteriorhodopsin: the role of the interhelical loops in the folding and stability of bacteriorhodopsin. | Journal of molecular biology 20010427 |
Structure and function in bacteriorhodopsin: the effect of the interhelical loops on the protein folding kinetics. | Journal of molecular biology 20010427 |
Proline residues in transmembrane alpha helices affect the folding of bacteriorhodopsin. | Journal of molecular biology 20010427 |
ABCR, the ATP-binding cassette transporter responsible for Stargardt macular dystrophy, is an efficient target of all-trans-retinal-mediated photooxidative damage in vitro. Implications for retinal disease. | The Journal of biological chemistry 20010413 |
All-trans-retinal forms a visible-absorbing pigment with human rod opsin. | Biochemistry 20010410 |
Halide dependence of the halorhodopsin photocycle as measured by time-resolved infrared spectra. | Biophysical journal 20010301 |
The relationship between opsin overexpression and photoreceptor degeneration. | Investigative ophthalmology & visual science 20010301 |
Visual cycle impairment in cellular retinaldehyde binding protein (CRALBP) knockout mice results in delayed dark adaptation. | Neuron 20010301 |
Role of noncovalent binding of 11-cis-retinal to opsin in dark adaptation of rod and cone photoreceptors. | Neuron 20010301 |
brp and blh are required for synthesis of the retinal cofactor of bacteriorhodopsin in Halobacterium salinarum. | The Journal of biological chemistry 20010223 |
Interphotoreceptor retinoid-binding protein contains three retinoid binding sites. | Experimental eye research 20010201 |
Ocular phenotype of bothnia dystrophy, an autosomal recessive retinitis pigmentosa associated with an R234W mutation in the RLBP1 gene. | Archives of ophthalmology (Chicago, Ill. : 1960) 20010201 |
Ternary complexes of liver alcohol dehydrogenase. | Chemico-biological interactions 20010130 |
Bioinorganic and bioorganic studies of liver alcohol dehydrogenase. | Chemico-biological interactions 20010130 |
Salt dependence of the formation and stability of the signaling state in G protein-coupled receptors: evidence for the involvement of the Hofmeister effect. | Biochemistry 20010116 |
Inherent chirality of the retinal chromophore in rhodopsin-A nonempirical theoretical analysis of chiroptical data. | Chirality 20010101 |
Nucleotide and deduced amino acid sequence of equine retinal and pineal gland phosducin. | American journal of veterinary research 20010101 |
Studies of all-trans-retinal as a photooxidizing agent. | Photochemistry and photobiology 20010101 |
The role of retinal in the long-range protein-lipid interactions in bacteriorhodopsin-phosphatidylcholine vesicles. | European biophysics journal : EBJ 20010101 |
Xanthine oxidase catalyzes the synthesis of retinoic acid. | Journal of enzyme inhibition 20010101 |
Oxidative DNA damage by vitamin A and its derivative via superoxide generation. | The Journal of biological chemistry 20000121 |
Metabolism of retinaldehyde and other aldehydes in soluble extracts of human liver and kidney. | The Journal of biological chemistry 19991119 |
Tolerance profile of retinol, retinaldehyde and retinoic acid under maximized and long-term clinical conditions. | Dermatology (Basel, Switzerland) 19990101 |
Structural and functional characterization of recombinant human cellular retinaldehyde-binding protein. | Protein science : a publication of the Protein Society 19980301 |
Synthesis and characterization of a novel retinylamine analog inhibitor of constitutively active rhodopsin mutants found in patients with autosomal dominant retinitis pigmentosa. | Proceedings of the National Academy of Sciences of the United States of America 19971209 |
Active site-directed inactivation of constitutively active mutants of rhodopsin. | The Journal of biological chemistry 19940304 |
Virucidal activity of retinal. | Antimicrobial agents and chemotherapy 19790901 |
Photoreceptor protein from the purple membrane of Halobacterium halobium. Molecular weight and retinal binding site. | Biochemistry 19760224 |
Biochemical aspects of the visual process. XXXI. Chemical modification studies on rod outer segment retinol dehydrogenase. | Experimental eye research 19751201 |