Home Other Building Blocks 2-(Pyrrolidin-2-yl)acetic acid

2-(Pyrrolidin-2-yl)acetic acid

CAS No.:
56879-46-0
Catalog Number:
AG00EEEP
Molecular Formula:
C6H11NO2
Molecular Weight:
129.1570
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Product Description
Catalog Number:
AG00EEEP
Chemical Name:
2-(Pyrrolidin-2-yl)acetic acid
CAS Number:
56879-46-0
Molecular Formula:
C6H11NO2
Molecular Weight:
129.1570
MDL Number:
MFCD08458431
IUPAC Name:
2-pyrrolidin-2-ylacetic acid
InChI:
InChI=1S/C6H11NO2/c8-6(9)4-5-2-1-3-7-5/h5,7H,1-4H2,(H,8,9)
InChI Key:
ADSALMJPJUKESW-UHFFFAOYSA-N
SMILES:
OC(=O)CC1CCCN1
Properties
Complexity:
114  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
129.079g/mol
Formal Charge:
0
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
129.159g/mol
Monoisotopic Mass:
129.079g/mol
Rotatable Bond Count:
2  
Topological Polar Surface Area:
49.3A^2
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0
XLogP3:
-2.4  
Literature
Title Journal
Mechanism and optimisation of the homoboroproline bifunctional catalytic asymmetric aldol reaction: Lewis acid tuning through in situ esterification. Organic & biomolecular chemistry 20120328
Ruthenium-catalysed synthesis of fluorinated bicyclic amino esters through tandem carbene addition/cyclopropanation of enynes. Chemistry (Weinheim an der Bergstrasse, Germany) 20110816
Is β-homo-proline a pseudo-γ-turn forming element of β-peptides? An IR and VCD spectroscopic study on Ac-β-HPro-NHMe in cryogenic matrices and solutions. Physical chemistry chemical physics : PCCP 20101107
Synthesis of alpha-cyclopropyl-beta-homoprolines. The Journal of organic chemistry 20090605
Improved protocol for asymmetric, intramolecular heteroatom Michael addition using organocatalysis: enantioselective syntheses of homoproline, pelletierine, and homopipecolic acid. The Journal of organic chemistry 20080704
Three-component synthesis of polysubstituted homoproline analogs. Molecules (Basel, Switzerland) 20050831
Synthesis and biological evaluation of new GABA-uptake inhibitors derived from proline and from pyrrolidine-2-acetic acid. European journal of medicinal chemistry 20050301
GABA uptake inhibitors. Design, molecular pharmacology and therapeutic aspects. Current pharmaceutical design 20000801
1-(3-(9H-carbazol-9-yl)-1-propyl)-4-(2-methoxyphenyl)-4-piperidinol, a novel subtype selective inhibitor of the mouse type II GABA-transporter. British journal of pharmacology 19970301
Properties