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Cml

CAS No.:
5746-04-3
Catalog Number:
AG00EDB9
Molecular Formula:
C8H16N2O4
Molecular Weight:
204.2236
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1mg
≥95%
1 week
United States
$112
- +
5mg
≥95%
1 week
United States
$196
- +
25mg
≥ 97% (Assay by titration)
1 week
United States
$199
- +
100mg
≥ 97% (Assay by titration)
1 week
United States
$360
- +
250mg
≥ 97% (Assay by titration)
1 week
United States
$689
- +
1g
≥ 97% (Assay by titration)
1 week
United States
$2216
- +
Product Description
Catalog Number:
AG00EDB9
Chemical Name:
Cml
CAS Number:
5746-04-3
Molecular Formula:
C8H16N2O4
Molecular Weight:
204.2236
MDL Number:
MFCD04114278
IUPAC Name:
(2S)-2-amino-6-(carboxymethylamino)hexanoic acid
InChI:
InChI=1S/C8H16N2O4/c9-6(8(13)14)3-1-2-4-10-5-7(11)12/h6,10H,1-5,9H2,(H,11,12)(H,13,14)/t6-/m0/s1
InChI Key:
NUXSIDPKKIEIMI-LURJTMIESA-N
SMILES:
OC(=O)CNCCCC[C@@H](C(=O)O)N
UNII:
70YDX3Z2O7
Properties
Complexity:
196  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0
Exact Mass:
204.111g/mol
Formal Charge:
0
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
4  
Isotope Atom Count:
0
Molecular Weight:
204.226g/mol
Monoisotopic Mass:
204.111g/mol
Rotatable Bond Count:
8  
Topological Polar Surface Area:
113A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-5.2  
Literature
Title Journal
Receptor for advanced glycation end products (RAGE) knockout reduces fetal dysmorphogenesis in murine diabetic pregnancy. Reproductive toxicology (Elmsford, N.Y.) 20160701
Betanin reduces the accumulation and cross-links of collagen in high-fructose-fed rat heart through inhibiting non-enzymatic glycation. Chemico-biological interactions 20150205
Graptopetalum paraguayense and resveratrol ameliorates carboxymethyllysine (CML)-induced pancreas dysfunction and hyperglycemia. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20131201
Suppression of dimerumic acid on hepatic fibrosis caused from carboxymethyl-lysine (CML) by attenuating oxidative stress depends on Nrf2 activation in hepatic stellate cells (HSCs). Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20131201
Formation and inhibition of Nε-(carboxymethyl)lysine in saccharide-lysine model systems during microwave heating. Molecules (Basel, Switzerland) 20121031
Plasma glycation levels are associated with severity in sepsis. European journal of clinical investigation 20121001
The alternative crosstalk between RAGE and nitrative thioredoxin inactivation during diabetic myocardial ischemia-reperfusion injury. American journal of physiology. Endocrinology and metabolism 20121001
Study of the urinary and faecal excretion of Nε-carboxymethyllysine in young human volunteers. Amino acids 20120801
Decreased plasma sRAGE levels in COPD: influence of oxygen therapy. European journal of clinical investigation 20120801
An explorative analysis of secretory receptor for advanced glycation endproducts in primary focal segmental glomerulosclerosis. Clinical and experimental nephrology 20120801
Aristolochic acid-induced accumulation of methylglyoxal and Nε-(carboxymethyl)lysine: an important and novel pathway in the pathogenic mechanism for aristolochic acid nephropathy. Biochemical and biophysical research communications 20120713
N-acetylcysteine reduces oxidative stress in sickle cell patients. Annals of hematology 20120701
Circulating selenium and carboxymethyl-lysine, an advanced glycation endproduct, are independent predictors of anemia in older community-dwelling adults. Nutrition (Burbank, Los Angeles County, Calif.) 20120701
Advanced glycation end-products as markers of aging and longevity in the long-lived Ansell's mole-rat (Fukomys anselli). The journals of gerontology. Series A, Biological sciences and medical sciences 20120601
Glycotoxin and autoantibodies are additive environmentally determined predictors of type 1 diabetes: a twin and population study. Diabetes 20120501
High serum advanced glycation end-products predict coronary artery disease irrespective of arterial stiffness in diabetic patients. Korean circulation journal 20120501
The associations of advanced glycation end products and its soluble receptor with pancreatic cancer risk: a case-control study within the prospective EPIC Cohort. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20120401
Advanced glycation end-product Nε-carboxymethyl-Lysine accelerates progression of atherosclerotic calcification in diabetes. Atherosclerosis 20120401
Improvement of arterial stiffness by reducing oxidative stress damage in elderly hypertensive patients after 6 months of atorvastatin therapy. Journal of clinical hypertension (Greenwich, Conn.) 20120401
Advanced glycation end-products, a pathophysiological pathway in the cardiorenal syndrome. Heart failure reviews 20120301
Endogenous formation of Nε-(carboxymethyl)lysine is increased in fatty livers and induces inflammatory markers in an in vitro model of hepatic steatosis. Journal of hepatology 20120301
Two fluorescent wavelengths, 440(ex)/520(em) nm and 370(ex)/440(em) nm, reflect advanced glycation and oxidation end products in human skin without diabetes. Diabetes technology & therapeutics 20120301
Advanced glycation end products contribute to the immunogenicity of IFN-β pharmaceuticals. The Journal of allergy and clinical immunology 20120301
Peripheral RAGE (receptor for advanced glycation endproducts)-ligands in normal pregnancy and preeclampsia: novel markers of inflammatory response. Journal of reproductive immunology 20120301
Ellagic acid, a new antiglycating agent: its inhibition of Nϵ-(carboxymethyl)lysine. The Biochemical journal 20120215
Skin autofluorescence is increased in patients with carotid artery stenosis and peripheral artery disease. The international journal of cardiovascular imaging 20120201
N(ɛ)-(carboxymethyl)lysine modification of elastin alters its biological properties: implications for the accumulation of abnormal elastic fibers in actinic elastosis. The Journal of investigative dermatology 20120201
Ω3-Polyunsaturated fatty acids prevent lipoperoxidation, modulate antioxidant enzymes, and reduce lipid content but do not alter glycogen metabolism in the livers of diabetic rats fed on a high fat thermolyzed diet. Molecular and cellular biochemistry 20120201
Formation of early and advanced Maillard reaction products correlates to the ripening of cheese. Journal of agricultural and food chemistry 20120118
'NEPP' peritoneal dialysis regimen has beneficial effects on plasma CEL and 3-DG, but not pentosidine, CML, and MGO. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20120101
Dietary intake associated with serum versus urinary carboxymethyl-lysine, a major advanced glycation end product, in adults: the Energetics Study. European journal of clinical nutrition 20120101
Olmesartan medoxomil is associated with decreased plasma AGEs, pentosidine, and N-(epsilon)-carboxymethyl-lysine levels in hemodialysis patients. Clinical and experimental hypertension (New York, N.Y. : 1993) 20120101
Cinnamic acid and its derivatives inhibit fructose-mediated protein glycation. International journal of molecular sciences 20120101
Effects of chronic calorie restriction or dietary resveratrol supplementation on insulin sensitivity markers in a primate, Microcebus murinus. PloS one 20120101
RAGE mediates accelerated diabetic vein graft atherosclerosis induced by combined mechanical stress and AGEs via synergistic ERK activation. PloS one 20120101
Serum levels of advanced glycation endproducts and other markers of protein damage in early diabetic nephropathy in type 1 diabetes. PloS one 20120101
Rosiglitazone modulates the behaviors of diabetic host-derived fibroblasts in a carboxymethyllysine-modified collagen model. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20120101
Induction of oxidative stress in kidney. International journal of nephrology 20120101
Aldose reductase, oxidative stress, and diabetic mellitus. Frontiers in pharmacology 20120101
The effects of low-dose nepsilon-(carboxymethyl)lysine (CML) and nepsilon-(carboxyethyl)lysine (CEL), two main glycation free adducts considered as potential uremic toxins, on endothelial progenitor cell function. Cardiovascular diabetology 20120101
SOD1 (copper/zinc superoxide dismutase) deficiency drives amyloid β protein oligomerization and memory loss in mouse model of Alzheimer disease. The Journal of biological chemistry 20111230
Irbesartan treatment does not influence plasma levels of the advanced glycation end products N(epsilon)(1-carboxymethyl)lysine and N(epsilon)(1-carboxyethyl)lysine in patients with type 2 diabetes and microalbuminuria. A randomized controlled trial. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20111101
UV B-irradiation enhances the racemization and isomerizaiton of aspartyl residues and production of Nε-carboxymethyl lysine (CML) in keratin of skin. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111101
Development of monoclonal antibodies specific for glycated prion protein. Journal of toxicology and environmental health. Part A 20111101
The presence of N(ε)-(Carboxymethyl) lysine in the human epidermis. Biochimica et biophysica acta 20111001
Association of sVAP-1, sRAGE, and CML with lactation-induced insulin sensitivity in young non-diabetic healthy women. Clinica chimica acta; international journal of clinical chemistry 20110918
AGE formation blockade with aminoguanidine does not ameliorate chronic allograft nephropathy. Life sciences 20110912
RAGE-dependent activation of the oncoprotein Pim1 plays a critical role in systemic vascular remodeling processes. Arteriosclerosis, thrombosis, and vascular biology 20110901
Age- and sun exposure-dependent differences in 8-hydroxy-2'-deoxyguanosine and N-(carboxymethyl)lysine in human epidermis. Journal of clinical biochemistry and nutrition 20110901
Skin advanced glycation end product accumulation and muscle strength among adult men. European journal of applied physiology 20110701
Circulating levels and dietary intake of the advanced glycation end-product marker carboxymethyl lysine in chronic kidney disease patients on conservative predialysis therapy: a pilot study. Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20110701
Protective role of adiponectin on endothelial dysfunction induced by AGEs: a clinical and experimental approach. Microvascular research 20110701
Spermatogenic and sperm quality differences in an experimental model of metabolic syndrome and hypogonadal hypogonadism. Reproduction (Cambridge, England) 20110701
Advanced glycation end products (AGEs) increase human mesangial foam cell formation by increasing Golgi SCAP glycosylation in vitro. American journal of physiology. Renal physiology 20110701
Decreased cerebrovascular brain-derived neurotrophic factor-mediated neuroprotection in the diabetic brain. Diabetes 20110601
Transport of free and peptide-bound glycated amino acids: synthesis, transepithelial flux at Caco-2 cell monolayers, and interaction with apical membrane transport proteins. Chembiochem : a European journal of chemical biology 20110516
Differential effects of advanced glycation end-products on renal tubular cell inflammation. Nephrology (Carlton, Vic.) 20110501
An autoantibody against N(ε)-(carboxyethyl)lysine (CEL): possible involvement in the removal of CEL-modified proteins by macrophages. Biochemical and biophysical research communications 20110408
Natural compounds containing a catechol group enhance the formation of Nε-(carboxymethyl)lysine of the Maillard reaction. Free radical biology & medicine 20110401
Endogenous secretory receptor for advanced glycation end products is associated with low serum interleukin-1 receptor antagonist and elevated IL-6 in older community-dwelling adults. The journals of gerontology. Series A, Biological sciences and medical sciences 20110401
Protection from retinopathy and other complications in patients with type 1 diabetes of extreme duration: the joslin 50-year medalist study. Diabetes care 20110401
Advanced glycation end-products accumulation compromises embryonic development and achievement of pregnancy by assisted reproductive technology. Human reproduction (Oxford, England) 20110301
Carbonylation contributes to SERCA2a activity loss and diastolic dysfunction in a rat model of type 1 diabetes. Diabetes 20110301
Oxidative damage in the liver of rats treated with glycolaldehyde. International journal of toxicology 20110301
Alpha-synuclein deficiency leads to increased glyoxalase I expression and glycation stress. Cellular and molecular life sciences : CMLS 20110201
Mapping the glycoxidation product Nε-carboxymethyllysine in the milk proteome. Proteomics 20110201
Higher plasma levels of advanced glycation end products are associated with incident cardiovascular disease and all-cause mortality in type 1 diabetes: a 12-year follow-up study. Diabetes care 20110201
Pentosidine and N-carboxymethyl-lysine: biomarkers for type 2 diabetic retinopathy. European journal of ophthalmology 20110101
The influence of bicarbonate/lactate-buffered PD fluids on N{ε}-(carboxyethyl)lysine and N{ε}-(carboxymethyl)lysine in peritoneal effluent. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20110101
Inhibition of advanced glycation end product formation by medicinal plant extracts correlates with phenolic metabolites and antioxidant activity. Planta medica 20110101
Relationship between advanced glycation end products and increased lipid peroxidation in semen of diabetic men. Diabetes research and clinical practice 20110101
AGE-RAGE in multiple sclerosis brain. Immunological investigations 20110101
Relationship between intima-media thickness of the common carotid artery and arterial stiffness in subjects with and without type 2 diabetes: a case-series report. Cardiovascular diabetology 20110101
Elevated Nε-(carboxymethyl)lysine is associated with apoptosis of retinal pericytes in streptozotocin-induced diabetic rats. Ophthalmic research 20110101
Soluble receptor for advanced glycation end products in COPD: relationship with emphysema and chronic cor pulmonale: a case-control study. Respiratory research 20110101
The metabolic advantage of tumor cells. Molecular cancer 20110101
Temporal increases in urinary carboxymethyllysine correlate with albuminuria development in diabetes. American journal of nephrology 20110101
Topical application of L-arginine blocks advanced glycation by ascorbic acid in the lens of hSVCT2 transgenic mice. Molecular vision 20110101
Advanced glycation endproducts are increased in rheumatoid arthritis patients with controlled disease. Arthritis research & therapy 20110101
Rapamycin prevents endothelial cell migration by inhibiting the endothelial-to-mesenchymal transition and matrix metalloproteinase-2 and -9: an in vitro study. Molecular vision 20110101
Glycolaldehyde induces oxidative stress in the heart: a clue to diabetic cardiomyopathy? Cardiovascular toxicology 20101201
Evaluation of loganin, iridoid glycoside from Corni Fructus, on hepatic and renal glucolipotoxicity and inflammation in type 2 diabetic db/db mice. European journal of pharmacology 20101201
Dietary advanced glycation end products and aging. Nutrients 20101201
Immunochemical and mass spectrometric analysis of Nε-(carboxymethyl)lysine content of AGE-BSA systems prepared with and without selected antiglycation agents. Journal of agricultural and food chemistry 20101124
Effect of inhibitor compounds on Nε-(carboxymethyl)lysine (CML) and Nε-(carboxyethyl)lysine (CEL) formation in model foods. Journal of agricultural and food chemistry 20101124
Advanced glycation end products on stored red blood cells increase endothelial reactive oxygen species generation through interaction with receptor for advanced glycation end products. Transfusion 20101101
Polyphenols and human health: prevention of disease and mechanisms of action. Nutrients 20101101
Differences in mouse models of diabetes mellitus in studies of male reproduction. International journal of andrology 20101001
N(ɛ)-(carboxymethyl)lysine linkage to α-synuclein and involvement of advanced glycation end products in α-synuclein deposits in an MPTP-intoxicated mouse model. Biochimie 20101001
Maternally transmitted and food-derived glycotoxins: a factor preconditioning the young to diabetes? Diabetes care 20101001
Circulating glycolaldehyde induces oxidative damage in the kidney of rats. Diabetes research and clinical practice 20100901
Circulating high-molecular-weight RAGE ligands activate pathways implicated in the development of diabetic nephropathy. Kidney international 20100801
Regarding 'Serum carboxymethyllysine concentrations are reduced in diabetic men with abdominal aortic aneurysms: Health In Men Study'. Journal of vascular surgery 20100801
Relationship of a dominant advanced glycation end product, serum carboxymethyl-lysine, and abnormal glucose metabolism in adults: the Baltimore Longitudinal Study of Aging. The journal of nutrition, health & aging 20100801
Combined immunoelectron microscopic and computer-assisted image analyses to detect advanced glycation end-products in human myocardium. Histochemistry and cell biology 20100701
Glycoxidative stress-induced mitophagy modulates mitochondrial fates. Annals of the New York Academy of Sciences 20100701
Beneficial effects of cinnamon proanthocyanidins on the formation of specific advanced glycation endproducts and methylglyoxal-induced impairment on glucose consumption. Journal of agricultural and food chemistry 20100609
Possible links between intestinal permeability and food processing: A potential therapeutic niche for glutamine. Clinics (Sao Paulo, Brazil) 20100601
Increased levels of N(epsilon)-(carboxymethyl)lysine in epithelial lining fluid from peripheral airways in patients with chronic obstructive pulmonary disease: a pilot study. Clinical science (London, England : 1979) 20100506
Inhibitory effect of the Cree traditional medicine wiishichimanaanh (Vaccinium vitis-idaea) on advanced glycation endproduct formation: identification of active principles. Phytotherapy research : PTR 20100501
Hyperglycaemia-induced impairment of endothelium-dependent vasorelaxation in rat mesenteric arteries is mediated by intracellular methylglyoxal levels in a pathway dependent on oxidative stress. Diabetologia 20100501
Validity of measurement of two specific biomarkers for the assessment of small airways inflammation in asthma. The Journal of asthma : official journal of the Association for the Care of Asthma 20100501
Modulation of advanced glycation endproduct synthesis by kynurenines in human lens proteins. Biochimica et biophysica acta 20100401
Increased glycation and oxidative damage to apolipoprotein B100 of LDL cholesterol in patients with type 2 diabetes and effect of metformin. Diabetes 20100401
Advanced glycation end-products, anti-hypertensive treatment and diastolic function in patients with hypertension and diastolic dysfunction. European journal of heart failure 20100401
Model studies on chemical and textural modifications in gelatin films by reaction with glyoxal and glycolaldehyde. Journal of agricultural and food chemistry 20100324
Effect of reactive-aldehydes on the modification and dysfunction of human serum albumin. Journal of pharmaceutical sciences 20100301
Serum carboxymethyl-lysine, a dominant advanced glycation end product, is associated with chronic kidney disease: the Baltimore longitudinal study of aging. Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20100301
AGER1 regulates endothelial cell NADPH oxidase-dependent oxidant stress via PKC-delta: implications for vascular disease. American journal of physiology. Cell physiology 20100301
Hyperglycemia impairs proteasome function by methylglyoxal. Diabetes 20100301
Cardiovascular autonomic neuropathy, HDL cholesterol, and smoking correlate with arterial stiffness markers determined 18 years later in type 1 diabetes. Diabetes care 20100301
Citric acid inhibits development of cataracts, proteinuria and ketosis in streptozotocin (type 1) diabetic rats. Biochemical and biophysical research communications 20100226
Anti-glycative effects of oleanolic acid and ursolic acid in kidney of diabetic mice. European journal of pharmacology 20100225
Formation of N(epsilon)-(carboxymethyl)lysine and loss of lysine in casein glucose-fatty acid model systems. Journal of agricultural and food chemistry 20100210
Plasma sRAGE is not associated with urinary microalbumin excretion in type 2 diabetic nephropathy at the early stage. Diabetes research and clinical practice 20100201
Carboxymethylation of the fibrillar collagen with respect to formation of hydroxyapatite. Journal of biomedical materials research. Part B, Applied biomaterials 20100201
Diabetes-associated changes and role of N epsilon-(carboxymethyl)lysine in big ET-1-induced coronary vasoconstriction. Peptides 20100201
Involvement of advanced glycation end-products, pentosidine and N(epsilon)-(carboxymethyl)lysine, in doxorubicin-induced cardiomyopathy in rats. Toxicology 20100131
Consequences of delayed pump infusion line change in patients with type 1 diabetes mellitus treated with continuous subcutaneous insulin infusion. Journal of diabetes and its complications 20100101
Effects of epalrestat, an aldose reductase inhibitor, on diabetic peripheral neuropathy in patients with type 2 diabetes, in relation to suppression of N(ɛ)-carboxymethyl lysine. Journal of diabetes and its complications 20100101
Relationship of an advanced glycation end product, plasma carboxymethyl-lysine, with slow walking speed in older adults: the InCHIANTI study. European journal of applied physiology 20100101
Vitamin B6 metabolism in chronic kidney disease--relation to transsulfuration, advanced glycation and cardiovascular disease. Nephron. Clinical practice 20100101
Effects of increased iron intake during the neonatal period on the brain of adult AbetaPP/PS1 transgenic mice. Journal of Alzheimer's disease : JAD 20100101
Effects of heat-processed ginseng and its active component ginsenoside 20(S)-Rg3 on the progression of renal damage and dysfunction in type 2 diabetic Otsuka Long-Evans Tokushima Fatty rats. Biological & pharmaceutical bulletin 20100101
NADPH Oxidase versus Mitochondria-Derived ROS in Glucose-Induced Apoptosis of Pericytes in Early Diabetic Retinopathy. Journal of ophthalmology 20100101
Advanced glycation end products, oxidative stress and diabetic nephropathy. Oxidative medicine and cellular longevity 20100101
Carotid intima-media thickness in individuals with and without type 2 diabetes: a reproducibility study. Cardiovascular diabetology 20100101
Chondroprotective effects and mechanisms of resveratrol in advanced glycation end products-stimulated chondrocytes. Arthritis research & therapy 20100101
Diagnostic potential of plasma carboxymethyllysine and carboxyethyllysine in multiple sclerosis. Journal of neuroinflammation 20100101
GCKR gene functional variants in type 2 diabetes and metabolic syndrome: do the rare variants associate with increased carotid intima-media thickness? Cardiovascular diabetology 20100101
Increased levels of the calcification marker matrix Gla Protein and the inflammatory markers YKL-40 and CRP in patients with type 2 diabetes and ischemic heart disease. Cardiovascular diabetology 20100101
Role of the receptor for advanced glycation end products in hepatic fibrosis. World journal of gastroenterology 20091214
High plasma levels of the soluble receptor for advanced glycation endproducts in patients with symptomatic carotid atherosclerosis. European journal of clinical investigation 20091201
Association of polymorphism in the receptor for advanced glycation end products (RAGE) gene with circulating RAGE levels. The Journal of clinical endocrinology and metabolism 20091201
Regular moderate exercise reduces advanced glycation and ameliorates early diabetic nephropathy in obese Zucker rats. Metabolism: clinical and experimental 20091101
Reductive metabolism of AGE precursors: a metabolic route for preventing AGE accumulation in cardiovascular tissue. Diabetes 20091101
Plasma carboxymethyl-lysine, an advanced glycation end product, and all-cause and cardiovascular disease mortality in older community-dwelling adults. Journal of the American Geriatrics Society 20091001
Evidence for increased methylglyoxal in the vasculature of women with preeclampsia: role in upregulation of LOX-1 and arginase. Hypertension (Dallas, Tex. : 1979) 20091001
Influence of insulin and muscle fiber type in nepsilon-(carboxymethyl)-lysine accumulation in soleus muscle of rats with streptozotocin-induced diabetes mellitus. Pathobiology : journal of immunopathology, molecular and cellular biology 20091001
Association between serum levels of the soluble receptor (sRAGE) for advanced glycation endproducts (AGEs) and their receptor (RAGE) in peripheral blood mononuclear cells of children with type 1 diabetes mellitus. Journal of pediatric endocrinology & metabolism : JPEM 20091001
Novel application of surface plasmon resonance biosensor chips for measurement of advanced glycation end products in serum of Zucker diabetic fatty rats. Biosensors & bioelectronics 20090915
Astragalosides isolated from the root of astragalus radix inhibit the formation of advanced glycation end products. Journal of agricultural and food chemistry 20090909
Serum carboxymethyllysine concentrations are reduced in diabetic men with abdominal aortic aneurysms: Health In Men Study. Journal of vascular surgery 20090901
Editorial: A recipe for inflammation. Journal of leukocyte biology 20090901
Advanced glycation end products accumulate in the reproductive tract of men with diabetes. International journal of andrology 20090801
Plasma protein pentosidine and carboxymethyllysine, biomarkers for age-related macular degeneration. Molecular & cellular proteomics : MCP 20090801
Naturally occurring flavonoids attenuate high glucose-induced expression of proinflammatory cytokines in human monocytic THP-1 cells. Molecular nutrition & food research 20090801
Matcha, a powdered green tea, ameliorates the progression of renal and hepatic damage in type 2 diabetic OLETF rats. Journal of medicinal food 20090801
Beneficial effects of Chinese prescription Kangen-karyu on diabetes associated with hyperlipidemia, advanced glycation endproducts, and oxidative stress in streptozotocin-induced diabetic rats. Journal of ethnopharmacology 20090715
The amelioration of streptozotocin diabetes-induced renal damage by Wu-Ling-San (Hoelen Five Herb Formula), a traditional Chinese prescription. Journal of ethnopharmacology 20090715
Advanced lipoxidation end-products mediate lipid-induced glomerular injury: role of receptor-mediated mechanisms. The Journal of pathology 20090701
Decrease in serum levels of advanced glycation end-products by short-term lifestyle modification in non-diabetic middle-aged females. Medical science monitor : international medical journal of experimental and clinical research 20090601
Effect of N-epsilon-(carboxymethyl)lysine on coronary vasoconstriction in isolated perfused hearts from control and streptozotocin-induced diabetic rats. Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20090601
Specific local cardiovascular changes of Nepsilon-(carboxymethyl)lysine, vascular endothelial growth factor, and Smad2 in the developing embryos coincide with maternal diabetes-induced congenital heart defects. Diabetes 20090501
Elevated serum advanced glycation end products and their circulating receptors are associated with anaemia in older community-dwelling women. Age and ageing 20090501
Glycoxidized LDL increases lectin-like oxidized low density lipoprotein receptor-1 in diabetes mellitus. Atherosclerosis 20090401
Advanced glycation end products regulate extracellular matrix protein and protease expression by human glomerular mesangial cells. International journal of molecular medicine 20090401
7-O-galloyl-D-sedoheptulose is a novel therapeutic agent against oxidative stress and advanced glycation endproducts in the diabetic kidney. Biological & pharmaceutical bulletin 20090401
Immunohistochemical detection of advanced glycation end products in human bladder with specific monoclonal antibody. International journal of urology : official journal of the Japanese Urological Association 20090401
Advanced glycation end products and their circulating receptors predict cardiovascular disease mortality in older community-dwelling women. Aging clinical and experimental research 20090401
Analysis of advanced glycation endproducts in dairy products by isotope dilution liquid chromatography-electrospray tandem mass spectrometry. The particular case of carboxymethyllysine. Journal of chromatography. A 20090320
Letter by Hartog et al. regarding article, 'Advanced glycation end products accumulate in vascular smooth muscle and modify vascular but not ventricular properties in elderly hypertensive canines'. Circulation 20090317
Ultra performance liquid chromatography-mass spectrometric determination of the site specificity of modification of beta-casein by glucose and methylglyoxal. Amino acids 20090301
Molecular pathogenesis of Alzheimer's disease: reductionist versus expansionist approaches. International journal of molecular sciences 20090301
Determination of Nepsilon-(carboxymethyl)lysine in food systems by ultra performance liquid chromatography-mass spectrometry. Amino acids 20090201
Carboxymethyl-lysine, an advanced glycation end product, and decline of renal function in older community-dwelling adults. European journal of nutrition 20090201
Advanced glycation end products increase transglutaminase activity in primary porcine tenocytes. Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20090201
Plasma advanced glycation end products are decreased in obese children compared with lean controls. International journal of pediatric obesity : IJPO : an official journal of the International Association for the Study of Obesity 20090101
Advanced glycation end products and their circulating receptors and level of kidney function in older community-dwelling women. American journal of kidney diseases : the official journal of the National Kidney Foundation 20090101
Modification of collagen in vitro with respect to formation of Nepsilon-carboxymethyllysine. International journal of biological macromolecules 20090101
Serum carboxymethyl-lysine, an advanced glycation end product, is associated with increased aortic pulse wave velocity in adults. American journal of hypertension 20090101
N(epsilon)-(Carboxymethyl)lysine and Coronary Atherosclerosis-Associated Low Density Lipoprotein Abnormalities in Type 2 Diabetes: Current Status. Journal of clinical biochemistry and nutrition 20090101
Elevated serum advanced glycation end products and poor grip strength in older community-dwelling women. The journals of gerontology. Series A, Biological sciences and medical sciences 20090101
Rapid glycation with D-ribose induces globular amyloid-like aggregations of BSA with high cytotoxicity to SH-SY5Y cells. BMC cell biology 20090101
Elevation of the glycoxidation product N(epsilon)-(carboxymethyl)lysine in patients presenting with acute myocardial infarction. Clinical chemistry and laboratory medicine 20090101
RAGE (Receptor for Advanced Glycation Endproducts), RAGE ligands, and their role in cancer and inflammation. Journal of translational medicine 20090101
Medical bioremediation of age-related diseases. Microbial cell factories 20090101
Mechanical ventilation during experimental sepsis increases deposition of advanced glycation end products and myocardial inflammation. Critical care (London, England) 20090101
Combination effects of enalapril and losartan on lipid peroxidation in the kidneys of KK-Ay/Ta mice. Nephron. Experimental nephrology 20090101
Association between carotid diameter and the advanced glycation end product N-epsilon-carboxymethyllysine (CML). Cardiovascular diabetology 20090101
Advanced glycation endproducts in sepsis and mechanical ventilation: extra or leading man? Critical care (London, England) 20090101
Advanced glycation end products induce cell cycle arrest and proinflammatory changes in osteoarthritic fibroblast-like synovial cells. Arthritis research & therapy 20090101
Characterization of anti-advanced glycation end product antibodies to nonenzymatically lysine-derived and arginine-derived glycated products. Journal of immunoassay & immunochemistry 20090101
Matrix metalloproteinases in subjects with type 1 diabetes. BMC clinical pathology 20090101
The influence of sublethal blue light exposure on human RPE cells. Molecular vision 20090101
Determination of advanced glycation end-products on IgG in liver cirrhosis. Hepato-gastroenterology 20090101
Concentrations of receptor for advanced glycation end products, VEGF and CML in plasma, follicular fluid, and peritoneal fluid in women with and without endometriosis. Reproductive sciences (Thousand Oaks, Calif.) 20081201
Antiglycative and anti-VEGF effects of s-ethyl cysteine and s-propyl cysteine in kidney of diabetic mice. Molecular nutrition & food research 20081101
Association between serum carboxymethyl-lysine, a dominant advanced glycation end product, and anemia in adults: the Baltimore longitudinal study of aging. Journal of the American Geriatrics Society 20081101
Increased oxidation, glycoxidation, and lipoxidation of brain proteins in prion disease. Free radical biology & medicine 20081015
Increased serum advanced glycation end-products is a distinct finding in lean women with polycystic ovary syndrome (PCOS). Clinical endocrinology 20081001
Integrin-associated protein association with SRC homology 2 domain containing tyrosine phosphatase substrate 1 regulates igf-I signaling in vivo. Diabetes 20081001
Skin autofluorescence is increased in systemic lupus erythematosus but is not reflected by elevated plasma levels of advanced glycation endproducts. Rheumatology (Oxford, England) 20081001
Advanced glycation end products accumulate in vascular smooth muscle and modify vascular but not ventricular properties in elderly hypertensive canines. Circulation 20080902
Severity of diabetic microvascular complications is associated with a low soluble RAGE level. Diabetes & metabolism 20080901
Skin-autofluorescence, a measure of tissue advanced glycation end-products (AGEs), is related to diastolic function in dialysis patients. Journal of cardiac failure 20080901
What is the influence of renal function on the prognostic value of advanced glycation end-products and sRAGE in heart failure? Journal of cardiac failure 20080901
Pentosidine accumulation in human oocytes and their correlation to age-related apoptosis. Acta histochemica et cytochemica 20080828
Formation of lipid oxidation and isomerization products during processing of nuts and sesame seeds. Journal of agricultural and food chemistry 20080827
Plasma N-epsilon-(carboxymethyl)lysine levels are associated with the extent of vessel injury after coronary arterial stenting. Coronary artery disease 20080801
Effects of advanced glycation end products-inductor glyoxal and hydrogen peroxide as oxidative stress factors on rat retinal organ cultures and neuroprotection by UK-14,304. Journal of neurochemistry 20080801
Identification of AGE-precursors and AGE formation in glycation-induced BSA peptides. BMB reports 20080731
Renal N(epsilon)-carboxymethyllysine deposition after kidney transplantation. Transplantation 20080727
RAGE and modulation of ischemic injury in the diabetic myocardium. Diabetes 20080701
Comparison of N-epsilon-(Carboxymethyl)Lysine levels and percentage of eosinophils in induced sputum for assessment of small airway involvements in asthma. Medical science monitor : international medical journal of experimental and clinical research 20080701
Characteristics of neurons and glia in the brain of Fukuyama type congenital muscular dystrophy. Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology 20080701
Comparative LC-MS/MS profiling of free and protein-bound early and advanced glycation-induced lysine modifications in dairy products. Analytica chimica acta 20080609
Glutaraldehyde is an effective cross-linker for production of antibodies against advanced glycation end-products. Journal of immunological methods 20080520
Endothelial dysfunction in patients with chronic kidney disease results from advanced glycation end products (AGE)-mediated inhibition of endothelial nitric oxide synthase through RAGE activation. Clinical journal of the American Society of Nephrology : CJASN 20080501
Increased Nepsilon-(carboxymethyl)-lysine levels in cerebral blood vessels of diabetic patients and in a (streptozotocin-treated) rat model of diabetes mellitus. European journal of endocrinology 20080501
Effects of oral administration of Stephania tetrandra S. Moore on neovascularization of retinal and choroidal capillaries of diabetes in rats. Phytotherapy research : PTR 20080501
Inhibition of renin angiotensin system decreases renal protein oxidative damage in diabetic rats. Biochemical and biophysical research communications 20080411
N epsilon-(carboxymethyl)lysine during the early development of hypertension. Annals of the New York Academy of Sciences 20080401
Some natural compounds enhance N epsilon-(carboxymethyl)lysine formation. Annals of the New York Academy of Sciences 20080401
Usefulness of antibodies for evaluating the biological significance of AGEs. Annals of the New York Academy of Sciences 20080401
Increased methionine sulfoxide content of apoA-I in type 1 diabetes. Journal of lipid research 20080401
Attenuation of hypertension development by scavenging methylglyoxal in fructose-treated rats. Journal of hypertension 20080401
Role of maltol in advanced glycation end products and free radicals: in-vitro and in-vivo studies. The Journal of pharmacy and pharmacology 20080401
Determination of N epsilon-(carboxymethyl)lysine in foods and related systems. Annals of the New York Academy of Sciences 20080401
Plasma concentration and urinary excretion of N epsilon-(carboxymethyl)lysine in breast milk- and formula-fed infants. Annals of the New York Academy of Sciences 20080401
Induction of heat shock proteins and the proteasome system by casein-N epsilon-(carboxymethyl)lysine and N epsilon-(carboxymethyl)lysine in Caco-2 cells. Annals of the New York Academy of Sciences 20080401
Maillard products as biomarkers in cancer. Annals of the New York Academy of Sciences 20080401
Evidence against nitric oxide-quenching effects of chemically defined Maillard reaction products. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20080401
Immunochemical detection of Nepsilon-(carboxyethyl)lysine using a specific antibody. Journal of immunological methods 20080320
N(epsilon)-carboxymethyllysine-modified proteins are unable to bind to RAGE and activate an inflammatory response. Molecular nutrition & food research 20080301
Inhibition of NADPH oxidase prevents advanced glycation end product-mediated damage in diabetic nephropathy through a protein kinase C-alpha-dependent pathway. Diabetes 20080201
Identification of CML-modified proteins in hemofiltrate of diabetic patients by proteome analysis. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20080101
AGE-receptor-1 counteracts cellular oxidant stress induced by AGEs via negative regulation of p66shc-dependent FKHRL1 phosphorylation. American journal of physiology. Cell physiology 20080101
Bench-to-bedside review: The inflammation-perpetuating pattern-recognition receptor RAGE as a therapeutic target in sepsis. Critical care (London, England) 20080101
Cardiac troponin T and advanced glycation end-products in hemodialysis patients. American journal of nephrology 20080101
Serum levels of the advanced glycation end products Nepsilon-carboxymethyllysine and pentosidine are not influenced by treatment with the angiotensin receptor II type 1 blocker irbesartan in patients with type 2 diabetic nephropathy and hypertension. Nephron. Clinical practice 20080101
Early atherosclerosis in systemic sclerosis and its relation to disease or traditional risk factors. Arthritis research & therapy 20080101
Role of advanced glycation end products in diabetic neuropathy. Current pharmaceutical design 20080101
Caveolin-1 expression and stress-induced premature senescence in human intervertebral disc degeneration. Arthritis research & therapy 20080101
The clinical relevance of assessing advanced glycation endproducts accumulation in diabetes. Cardiovascular diabetology 20080101
Advanced glycation end products in pregnancies complicated with diabetes mellitus or preeclampsia. Hypertension in pregnancy 20080101
Progress and perspectives on the role of RPE cell inflammatory responses in the development of age-related macular degeneration. Journal of inflammation research 20080101
Markers of endothelial activity are related to components of the metabolic syndrome, but not to circulating concentrations of the advanced glycation end-product N epsilon-carboxymethyl-lysine in healthy Swedish men. Atherosclerosis 20071201
Clinical and prognostic value of advanced glycation end-products in chronic heart failure. European heart journal 20071201
Simultaneous analysis of lysine, Nepsilon-carboxymethyllysine and lysinoalanine from proteins. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071201
The ligand activity of AGE-proteins to scavenger receptors is dependent on their rate of modification by AGEs. Biochimica et biophysica acta 20071201
Nepsilon-(carboxymethyl)lysine, a major advanced glycation end product in exhaled breath condensate as a biomarker of small airway involvement in asthma. The Journal of asthma : official journal of the Association for the Care of Asthma 20071201
Current concepts in targeted therapies for the pathophysiology of diabetic microvascular complications. Vascular health and risk management 20071201
Succination of protein thiols during adipocyte maturation: a biomarker of mitochondrial stress. The Journal of biological chemistry 20071123
Advanced glycation end products and the absence of premature atherosclerosis in glycogen storage disease Ia. Journal of inherited metabolic disease 20071101
Anthraquinones from the seeds of Cassia tora with inhibitory activity on protein glycation and aldose reductase. Biological & pharmaceutical bulletin 20071101
Protective effect of heat-processed American ginseng against diabetic renal damage in rats. Journal of agricultural and food chemistry 20071017
Characterization of glycation adducts on human serum albumin by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Clinica chimica acta; international journal of clinical chemistry 20071001
Arguing for the motion: yes, RAGE is a receptor for advanced glycation endproducts. Molecular nutrition & food research 20070901
Lipoic acid and N-acetyl cysteine decrease mitochondrial-related oxidative stress in Alzheimer disease patient fibroblasts. Journal of Alzheimer's disease : JAD 20070901
Role of N-(carboxymethyl)lysine in the development of ischemic heart disease in type 2 diabetes mellitus. Journal of clinical biochemistry and nutrition 20070901
Vimentin is the specific target in skin glycation. Structural prerequisites, functional consequences, and role in skin aging. The Journal of biological chemistry 20070810
Pyridoxal phosphate prevents progression of diabetic nephropathy. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070801
Unchanged serum levels of advanced glycation endproducts in patients with liver disease. Naunyn-Schmiedeberg's archives of pharmacology 20070801
Site-specific formation of Maillard, oxidation, and condensation products from whey proteins during reaction with lactose. Journal of agricultural and food chemistry 20070725
Study of posttranslational non-enzymatic modifications of collagen using capillary electrophoresis/mass spectrometry and high performance liquid chromatography/mass spectrometry. Journal of chromatography. A 20070706
Reduced systemic advanced glycation end products in children receiving peritoneal dialysis with low glucose degradation product content. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070701
Fasting and postprandial glycoxidative and lipoxidative stress are increased in women with type 2 diabetes. Diabetes care 20070701
Advanced glycation endproducts: a biomarker for age as an outcome predictor after cardiac surgery? Experimental gerontology 20070701
Identification of antidiabetic effect of iridoid glycosides and low molecular weight polyphenol fractions of Corni Fructus, a constituent of Hachimi-jio-gan, in streptozotocin-induced diabetic rats. Biological & pharmaceutical bulletin 20070701
Hypochlorous acid generates N epsilon-(carboxymethyl)lysine from Amadori products. Free radical research 20070601
Kinetics of formation of three indicators of the maillard reaction in model cookies: influence of baking temperature and type of sugar. Journal of agricultural and food chemistry 20070530
Advanced glycation end products cause increased CCN family and extracellular matrix gene expression in the diabetic rodent retina. Diabetologia 20070501
Glycoxidised LDL isolated from subjects with impaired glucose tolerance increases CD36 and peroxisome proliferator-activator receptor gamma gene expression in macrophages. Diabetologia 20070501
Simultaneous determination of the advanced glycation end product N (epsilon)-carboxymethyllysine and its precursor, lysine, in exhaled breath condensate using isotope-dilution-hydrophilic-interaction liquid chromatography coupled to tandem mass spectrometry. Analytical and bioanalytical chemistry 20070401
Investigation of pathways of advanced glycation end-products accumulation in macrophages. Molecular nutrition & food research 20070401
Forty years of furosine - forty years of using Maillard reaction products as indicators of the nutritional quality of foods. Molecular nutrition & food research 20070401
Circulating glycotoxins and dietary advanced glycation endproducts: two links to inflammatory response, oxidative stress, and aging. The journals of gerontology. Series A, Biological sciences and medical sciences 20070401
Anti-inflammatory agents and monoHER protect against DOX-induced cardiotoxicity and accumulation of CML in mice. British journal of cancer 20070326
Circulating levels of Nepsilon-(carboxymethyl)lysine are increased in systemic sclerosis. Rheumatology (Oxford, England) 20070301
Functioning of oxidative phosphorylation in liver mitochondria of high-fat diet fed rats. Biochimica et biophysica acta 20070301
Maillard reaction indicators in diets usually consumed by adolescent population. Molecular nutrition & food research 20070301
Beneficial effect of Corni Fructus, a constituent of Hachimi-jio-gan, on advanced glycation end-product-mediated renal injury in Streptozotocin-treated diabetic rats. Biological & pharmaceutical bulletin 20070301
Advanced glycation end products induce apoptosis in fibroblasts through activation of ROS, MAP kinases, and the FOXO1 transcription factor. American journal of physiology. Cell physiology 20070201
Combination therapy with the advanced glycation end product cross-link breaker, alagebrium, and angiotensin converting enzyme inhibitors in diabetes: synergy or redundancy? Endocrinology 20070201
Effect of pyridoxamine (K-163), an inhibitor of advanced glycation end products, on type 2 diabetic nephropathy in KK-A(y)/Ta mice. Metabolism: clinical and experimental 20070201
Evaluation of a gas chromatography/mass spectrometry method for the quantification of carboxymethyllysine in food samples. Journal of chromatography. A 20070126
Advanced glycation end product deposits in climatic droplet keratopathy. The British journal of ophthalmology 20070101
Mesothelial RAGE activation by AGEs enhances VEGF release and potentiates capillary tube formation. Kidney international 20070101
Endogenous secretory receptor for advanced glycation endproducts levels are correlated with serum pentosidine and CML in patients with type 1 diabetes. Arteriosclerosis, thrombosis, and vascular biology 20070101
Overproduction of N(epsilon)-(carboxymethyl)lysine-induced neovascularization in cultured choroidal explant of aged rat. Biological & pharmaceutical bulletin 20070101
Pravastatin inhibits carboxymethyllysine-induced monocyte chemoattractant protein 1 expression in podocytes via prevention of signalling events. Nephron. Experimental nephrology 20070101
Activation of the RAGE pathway: a general mechanism in the pathogenesis of polyneuropathies? Neurological research 20070101
Carbonyl and oxidative stress in patients with breast cancer--is there a relation to the stage of the disease? Neoplasma 20070101
Cerebrotendinous xanthomatosis: case report with evidence of oxidative stress. Redox report : communications in free radical research 20070101
Amount of N(omega)-(Carboxymethyl)arginine generated in collagen and bovine serum albumin during glycation reactions is significantly different. Connective tissue research 20070101
Immunohistochemical study of N-epsilon-carboxymethyl lysine (CML) in human brain: relation to vascular dementia. BMC neurology 20070101
Iron homeostasis is maintained in the brain, but not the liver, following mild hypoxia. Redox report : communications in free radical research 20070101
Fluorescent serum and urinary advanced glycoxidation end-products in non- diabetic subjects. Biological research 20070101
Effects of valsartan therapy on protein glycoxidation. Metabolism: clinical and experimental 20061201
Circulating soluble receptor for advanced glycation end products is inversely associated with glycemic control and S100A12 protein. The Journal of clinical endocrinology and metabolism 20061101
The receptor for advanced glycation end products and its ligands: a new inflammatory pathway in lung disease? Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 20061101
N(epsilon)-(carboxymethyl)lysine depositions in intramyocardial blood vessels in human and rat acute myocardial infarction: a predictor or reflection of infarction? Arteriosclerosis, thrombosis, and vascular biology 20061101
Advanced glycation end-products and methionine sulphoxide in skin collagen of patients with type 1 diabetes. Diabetologia 20061001
The advanced glycation end product N(epsilon)-carboxymethyllysine is not a predictor of cardiovascular events and renal outcomes in patients with type 2 diabetic kidney disease and hypertension. American journal of kidney diseases : the official journal of the National Kidney Foundation 20061001
Posttranslationally modified proteins as mediators of sustained intestinal inflammation. The American journal of pathology 20061001
Argpyrimidine-modified Heat shock protein 27 in human non-small cell lung cancer: a possible mechanism for evasion of apoptosis. Cancer letters 20060928
Concentrations of Nepsilon-carboxymethyllysine in human breast milk, infant formulas, and urine of infants. Journal of agricultural and food chemistry 20060906
Dose-dependent utilisation of casein-linked lysinoalanine, N(epsilon)-fructoselysine and N(epsilon)-carboxymethyllysine in rats. Molecular nutrition & food research 20060901
Inhibition of advanced glycation end product formation on collagen by rutin and its metabolites. The Journal of nutritional biochemistry 20060801
High glucose and Nepsilon-(carboxymethyl) lysine bovine serum albumin modulate release of matrix metalloproteinases in cultured human endothelial cells. European journal of nutrition 20060801
Antioxidant tempol lowers age-related increases in insulin resistance in Fischer 344 rats. Clinical and experimental hypertension (New York, N.Y. : 1993) 20060701
Site specificity of glycation and carboxymethylation of bovine serum albumin by fructose. Amino acids 20060601
S-(2-Succinyl)cysteine: a novel chemical modification of tissue proteins by a Krebs cycle intermediate. Archives of biochemistry and biophysics 20060601
Transepithelial flux of early and advanced glycation compounds across Caco-2 cell monolayers and their interaction with intestinal amino acid and peptide transport systems. The British journal of nutrition 20060601
Should we reconsider the advanced glycation end product issue in hemodialysis patients? American journal of kidney diseases : the official journal of the National Kidney Foundation 20060501
Phage-displayed antibodies for the detection of glycated proteasome in aging cells. Annals of the New York Academy of Sciences 20060501
Postprandial mononuclear NF-kappaB activation is independent of the AGE-content of a single meal. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20060401
Aminoguanidine and metformin prevent the reduced rate of HDL-mediated cell cholesterol efflux induced by formation of advanced glycation end products. The international journal of biochemistry & cell biology 20060301
Oxidative stress in type 2 diabetes: the role of fasting and postprandial glycaemia. International journal of clinical practice 20060301
Inhibition of apoptosis and reduction of intracellular pH decrease in retinal neural cell cultures by a blocker of carbonic anhydrase. Investigative ophthalmology & visual science 20060301
Synthesis, tandem MS- and NMR-based characterization, and quantification of the carbon 13-labeled advanced glycation endproduct, 6-N-carboxymethyllysine. Amino acids 20060201
The receptor for advanced glycation end products is highly expressed in the skin and upregulated by advanced glycation end products and tumor necrosis factor-alpha. The Journal of investigative dermatology 20060201
Serum carboxymethyllysine predicts mortality in hemodialysis patients. American journal of kidney diseases : the official journal of the National Kidney Foundation 20060201
A severe diabetic nephropathy model with early development of nodule-like lesions induced by megsin overexpression in RAGE/iNOS transgenic mice. Diabetes 20060201
Interaction of Nepsilon(carboxymethyl)lysine- and methylglyoxal-modified albumin with endothelial cells and macrophages. Splice variants of RAGE may limit the responsiveness of human endothelial cells to AGEs. Thrombosis and haemostasis 20060201
Immunohistochemical localization of advanced glycation end products in pinguecula. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20060101
Impaired left ventricular relaxation in type 2 diabetic rats is related to myocardial accumulation of N(epsilon)-(carboxymethyl) lysine. European journal of heart failure 20060101
Elevation of Nepsilon-(carboxymethyl)lysine-modified advanced glycation end products in chronic liver disease is an indicator of liver cirrhosis. Clinical biochemistry 20060101
Advanced glycation end product modification of bone proteins and bone remodelling: hypothesis and preliminary immunohistochemical findings. Annals of the rheumatic diseases 20060101
Gender-related differences in advanced glycation endproducts, oxidative stress markers and nitric oxide synthases in rats. Kidney international 20060101
Increased proinflammatory endothelial response to S100A8/A9 after preactivation through advanced glycation end products. Cardiovascular diabetology 20060101
Early lens aging is accelerated in subjects with a high risk of ischemic heart disease: an epidemiologic study. BMC ophthalmology 20060101
Insights from the diabetes control and complications trial/epidemiology of diabetes interventions and complications study on the use of intensive glycemic treatment to reduce the risk of complications of type 1 diabetes. Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20060101
Biology and therapy of fibromyalgia: pain in fibromyalgia syndrome. Arthritis research & therapy 20060101
The increase in plasma levels of Nepsilon-(carboxymethyl)lysine during icodextrin treatment of peritoneal dialysis patients is not associated with increased plasma levels of vascular cell adhesion molecule-1. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20060101
Determination of N epsilon-(carboxymethyl)lysine in exhaled breath condensate using isotope dilution liquid chromatography/electrospray ionization tandem mass spectrometry. Rapid communications in mass spectrometry : RCM 20060101
Prevention and reversal of diabetic nephropathy in db/db mice treated with alagebrium (ALT-711). American journal of nephrology 20060101
Transition of healthy to diseased synovial tissue in rheumatoid arthritis is associated with gain of mesenchymal/fibrotic characteristics. Arthritis research & therapy 20060101
Oral adsorbent AST-120 decreases serum levels of AGEs in patients with chronic renal failure. Molecular medicine (Cambridge, Mass.) 20060101
Advanced glycation end product in diabetic rat skeletal muscle in vivo. Pathobiology : journal of immunopathology, molecular and cellular biology 20060101
Glycated and carboxy-methylated proteins do not directly activate human vascular smooth muscle cells. Kidney international 20051201
Oxidation and carboxy methyl lysine-modification of albumin: possible involvement in the progression of oxidative stress in hemodialysis patients. Hypertension research : official journal of the Japanese Society of Hypertension 20051201
Cardiovascular disease in diabetic nephropathy patients: cell adhesion molecules as potential markers? Vascular health and risk management 20051201
Rapid and simple method for determination of Nepsilon-(carboxymethyl)lysine and Nepsilon-(carboxyethyl)lysine in urine using gas chromatography/mass spectrometry. Biomedical chromatography : BMC 20051101
Glycation and carboxymethyllysine levels in skin collagen predict the risk of future 10-year progression of diabetic retinopathy and nephropathy in the diabetes control and complications trial and epidemiology of diabetes interventions and complications participants with type 1 diabetes. Diabetes 20051101
Oxidative stress and non-enzymatic glycation in IgA nephropathy. Clinical nephrology 20051101
Decreased levels of advanced glycation end-products in patients with Gilbert syndrome. Cellular and molecular biology (Noisy-le-Grand, France) 20050930
Development of age-dependent glomerular lesions in galectin-3/AGE-receptor-3 knockout mice. American journal of physiology. Renal physiology 20050901
Genomic damage and circulating AGE levels in patients undergoing daily versus standard haemodialysis. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20050901
The RAGE pathway in inflammatory myopathies and limb girdle muscular dystrophy. Acta neuropathologica 20050901
Chemoselective synthesis of peptides containing major advanced glycation end-products of lysine and arginine. The journal of peptide research : official journal of the American Peptide Society 20050901
Modulation of soluble receptor for advanced glycation end products by angiotensin-converting enzyme-1 inhibition in diabetic nephropathy. Journal of the American Society of Nephrology : JASN 20050801
Vascular methylglyoxal metabolism and the development of hypertension. Journal of hypertension 20050801
Renal accumulation and clearance of advanced glycation end-products in type 2 diabetic nephropathy: effect of angiotensin-converting enzyme and vasopeptidase inhibition. Diabetologia 20050801
Advanced glycation end products are associated with pulse pressure in type 1 diabetes: the EURODIAB Prospective Complications Study. Hypertension (Dallas, Tex. : 1979) 20050701
Assay of advanced glycation endproducts in selected beverages and food by liquid chromatography with tandem mass spectrometric detection. Molecular nutrition & food research 20050701
Proteins in human brain cortex are modified by oxidation, glycoxidation, and lipoxidation. Effects of Alzheimer disease and identification of lipoxidation targets. The Journal of biological chemistry 20050603
Labeling studies on the formation pathway of Nepsilon-carboxymethyllysine in maillard-type reactions. Annals of the New York Academy of Sciences 20050601
Effect of glucose concentration on formation of AGEs in erythrocytes in vitro. Annals of the New York Academy of Sciences 20050601
Oxidative stress and neurodegeneration. Annals of the New York Academy of Sciences 20050601
Low-molecular weight advanced glycation end products: markers of tissue AGE accumulation and more? Annals of the New York Academy of Sciences 20050601
Advanced glycation end products in human cancer tissues: detection of Nepsilon-(carboxymethyl)lysine and argpyrimidine. Annals of the New York Academy of Sciences 20050601
Advanced glycation end product free adducts are cleared by dialysis. Annals of the New York Academy of Sciences 20050601
Clinical implications of N epsilon-(carboxymethyl)lysine, advanced glycation end product, in children and adolescents with type 1 diabetes. Diabetes, obesity & metabolism 20050501
The AGE/RAGE/NF-(kappa)B pathway may contribute to the pathogenesis of polyneuropathy in impaired glucose tolerance (IGT). Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20050501
Advanced glycation end products enhance expression of pro-apoptotic genes and stimulate fibroblast apoptosis through cytoplasmic and mitochondrial pathways. The Journal of biological chemistry 20050401
Nuclear proteasome activation and degradation of carboxymethylated histones in human keratinocytes following glyoxal treatment. Free radical biology & medicine 20050315
Glyoxal inactivates glutamate transporter-1 in cultured rat astrocytes. Neuropathology : official journal of the Japanese Society of Neuropathology 20050301
Inhibitory effect of nifedipine on tumor necrosis factor alpha-induced neovascularization in cultured choroidal explants of streptozotocin-diabetic rat. Biological & pharmaceutical bulletin 20050201
Multiple metabolic hits converge on CD36 as novel mediator of tubular epithelial apoptosis in diabetic nephropathy. PLoS medicine 20050201
Apoptotic killing of fibroblasts by matrix-bound advanced glycation endproducts. Science of aging knowledge environment : SAGE KE 20050126
Reversal by aminoguanidine of the age-related increase in glycoxidation and lipoxidation in the cardiovascular system of Fischer 344 rats. Biochemical pharmacology 20050101
Development of capture assays for different modifications of human low-density lipoprotein. Clinical and diagnostic laboratory immunology 20050101
Protein glycation, oxidation and nitration adduct residues and free adducts of cerebrospinal fluid in Alzheimer's disease and link to cognitive impairment. Journal of neurochemistry 20050101
Two immunochemical assays to measure advanced glycation end-products in serum from dialysis patients. Clinical chemistry and laboratory medicine 20050101
Decreased levels of soluble receptor for advanced glycation end products in patients with rheumatoid arthritis indicating deficient inflammatory control. Arthritis research & therapy 20050101
The absorption and metabolism of modified amino acids in processed foods. Journal of AOAC International 20050101
[Advanced glycation and oxidation products in patients with atherosclerosis]. Casopis lekaru ceskych 20050101
Detection of elevated N epsilon-carboxymethyllysine levels in muscular tissue and in serum of patients with fibromyalgia. Scandinavian journal of rheumatology 20050101
HNE-dependent molecular damage in diabetic nephropathy and its possible prevention by N-acetyl-cysteine and oxerutin. BioFactors (Oxford, England) 20050101
Influence of icodextrin on plasma and dialysate levels of N(epsilon)-(carboxymethyl)lysine and N(epsilon)-(carboxyethyl)lysine. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20050101
Increased methylglyoxal and advanced glycation end products in kidney from spontaneously hypertensive rats. Kidney international 20041201
Relationship between blood levels of N-carboxymethyl-lysine and pentosidine and the severity of microangiopathy in type 2 diabetes. Endocrine journal 20041201
Conventional antibody against Nepsilon-(carboxymethyl)lysine (CML) shows cross-reaction to Nepsilon-(carboxyethyl)lysine (CEL): immunochemical quantification of CML with a specific antibody. Journal of biochemistry 20041201
The advanced glycation end-product N epsilon-(carboxymethyl)lysine level is elevated in cerebrospinal fluid of patients with amyotrophic lateral sclerosis. Neuroscience letters 20041123
Intact glycation end products containing carboxymethyl-lysine and glyoxal lysine dimer obtained from synthetic collagen model peptide. Bioorganic & medicinal chemistry letters 20041115
Galectin-3/AGE-receptor 3 knockout mice show accelerated AGE-induced glomerular injury: evidence for a protective role of galectin-3 as an AGE receptor. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20041101
Paradox of circulating advanced glycation end product concentrations in patients with congestive heart failure and after heart transplantation. Heart (British Cardiac Society) 20041101
In vitro evidence for immune activating effect of specific AGE structures retained in uremia. Kidney international 20041101
Overproduction of N(epsilon)-(carboxymethyl)lysine-induced neovascularization in cultured choroidal explant of streptozotocin-diabetic rat. Biological & pharmaceutical bulletin 20041001
Protein nonenzymatic modifications and proteasome activity in skeletal muscle from the short-lived rat and long-lived pigeon. Experimental gerontology 20041001
Liquid chromatographic method for the quantitative determination of Nepsilon-carboxymethyllysine in human plasma proteins. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040905
The triggering of human peritoneal mesothelial cell apoptosis and oncosis by glucose and glycoxydation products. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20040901
Effect of advanced glycation end-products on gene expression and synthesis of TNF-alpha and endothelial nitric oxide synthase by endothelial cells. Kidney international 20040901
N(epsilon)-(carboxymethyl)lysine proliferated CD34(+) cells from rat choroidal explant in culture. Biological & pharmaceutical bulletin 20040901
Nepsilon-(Carboxymethyl)lysine and 3-DG-imidazolone are major AGE structures in protein modification by 3-deoxyglucosone. Journal of biochemistry 20040901
Improvement of the quality of diabetes control and decrease in the concentrations of AGE-products in patients with type 1 and insulin-treated type 2 diabetes mellitus: results from a 10 year-prospective, population-based survey on the quality of diabetes care in Germany (JEVIN). European journal of medical research 20040831
Elevated serum levels of N(epsilon)-carboxymethyl-lysine, an advanced glycation end product, are associated with proliferative diabetic retinopathy and macular oedema. Diabetologia 20040801
Possible mechanism for medial smooth muscle cell injury in diabetic nephropathy: glycoxidation-mediated local complement activation. American journal of kidney diseases : the official journal of the National Kidney Foundation 20040801
Advanced glycoxidation end products in commonly consumed foods. Journal of the American Dietetic Association 20040801
Effect of ageing and caloric restriction on specific markers of protein oxidative damage and membrane peroxidizability in rat liver mitochondria. Mechanisms of ageing and development 20040801
Nonenzymatic glycation at the N terminus of pathogenic prion protein in transmissible spongiform encephalopathies. The Journal of biological chemistry 20040716
Measurement of Nepsilon-(carboxymethyl)lysine and Nepsilon-(carboxyethyl)lysine in human plasma protein by stable-isotope-dilution tandem mass spectrometry. Clinical chemistry 20040701
Potential cardiovascular risk factors in chronic kidney disease: AGEs, total homocysteine and metabolites, and the C-reactive protein. Kidney international 20040701
The Euro-Balance Trial: the effect of a new biocompatible peritoneal dialysis fluid (balance) on the peritoneal membrane. Kidney international 20040701
The clinical chemome: a tool for the diagnosis and management of chronic disease. Clinical chemistry 20040701
Simple non-invasive assessment of advanced glycation endproduct accumulation. Diabetologia 20040701
N(omega)-(carboxymethyl)lysine depositions in human aortic heart valves: similarities with atherosclerotic blood vessels. Atherosclerosis 20040601
A possible involvement of the carboxymethylation process in carpal tunnel syndrome in hemodialysis patients. Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 20040601
Receptor for advanced glycation endproduct (RAGE)-mediated nuclear factor-kappaB activation in vasculitic neuropathy. Muscle & nerve 20040601
N epsilon-carboxymethyllysine in brain aging, diabetes mellitus, and Alzheimer's disease. Free radical biology & medicine 20040515
Chemical modification of muscle protein in diabetes. Archives of biochemistry and biophysics 20040515
AGEs, macrophage colony stimulating factor and vascular adhesion molecule blood levels are increased in patients with diabetic microangiopathy. Thrombosis and haemostasis 20040501
Modification of the longevity-related degree of fatty acid unsaturation modulates oxidative damage to proteins and mitochondrial DNA in liver and brain. Experimental gerontology 20040501
Metal complexation by the peptide-bound maillard reaction products N(epsilon)-fructoselysine and N(epsilon)-carboxymethyllysine. Journal of agricultural and food chemistry 20040421
Nepsilon-(carboxymethyl)lysine, Nepsilon-(carboxyethyl)lysine and vascular cell adhesion molecule-1 (VCAM-1) in relation to peritoneal glucose prescription and residual renal function; a study in peritoneal dialysis patients. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20040401
Increased production of urea hydrogen peroxide from Maillard reaction and a UHP-Fenton pathway related to glycoxidation damage in chronic renal failure. Journal of the American Society of Nephrology : JASN 20040401
Increased accumulation of the glycoxidation product Nepsilon-(carboxymethyl)lysine in hearts of diabetic patients: generation and characterisation of a monoclonal anti-CML antibody. Biochimica et biophysica acta 20040322
Increased levels of N(epsilon)-(carboxymethyl)lysine and N(epsilon)-(carboxyethyl)lysine in type 1 diabetic patients with impaired renal function: correlation with markers of endothelial dysfunction. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20040301
Immunolocalization of lipid peroxidation/advanced glycation end products in amyloid A amyloidosis. Free radical biology & medicine 20040301
Influence of hemodialysis membrane permeability on serum levels of advanced glycation end products (AGEs) and homocysteine metabolites. Clinical nephrology 20040301
Oxidative damage in cultured human olfactory neurons from Alzheimer's disease patients. Aging cell 20040201
Advanced glycation end product ligands for the receptor for advanced glycation end products: biochemical characterization and formation kinetics. Analytical biochemistry 20040101
Tomato paste fraction inhibiting the formation of advanced glycation end-products. Bioscience, biotechnology, and biochemistry 20040101
A review of the 'mysterious' wasting disease in Swedish moose (Alces alces L.) related to molybdenosis and disturbances in copper metabolism. Biological trace element research 20040101
Renal clearance of glycation adducts: anti-glycation defence in uraemia and dialysis. Biochemical Society transactions 20031201
Accumulation of fructosyl-lysine and advanced glycation end products in the kidney, retina and peripheral nerve of streptozotocin-induced diabetic rats. Biochemical Society transactions 20031201
Modification of proteins in vitro by physiological levels of glucose: pyridoxamine inhibits conversion of Amadori intermediate to advanced glycation end-products through binding of redox metal ions. The Journal of biological chemistry 20031121
A quantitative model of the generation of N(epsilon)-(carboxymethyl)lysine in the Maillard reaction between collagen and glucose. The Biochemical journal 20031115
Adverse effects of dietary glycotoxins on wound healing in genetically diabetic mice. Diabetes 20031101
Paradoxical impact of antioxidants on post-Amadori glycoxidation: Counterintuitive increase in the yields of pentosidine and Nepsilon-carboxymethyllysine using a novel multifunctional pyridoxamine derivative. The Journal of biological chemistry 20031003
Lack of recognition of Nepsilon-(carboxymethyl)lysine by the mouse liver reticulo-endothelial system: implications for pathophysiology. Biochemical and biophysical research communications 20031003
Advanced glycation end-products pentosidine and N epsilon-carboxymethyllysine are elevated in serum of patients with osteoporosis. Rheumatology (Oxford, England) 20031001
Identification of Nepsilon-(carboxymethyl)lysine-positive cells in astroglia-rich primary cultures. Journal of neural transmission (Vienna, Austria : 1996) 20031001
Liquid chromatography-based determination of urinary free and total N(epsilon)-(carboxymethyl)lysine excretion in normal and diabetic subjects. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030905
Impact of metabolic control and serum lipids on the concentration of advanced glycation end products in the serum of children and adolescents with type 1 diabetes, as determined by fluorescence spectroscopy and nepsilon-(carboxymethyl)lysine ELISA. Diabetes care 20030901
Level of an advanced glycated end product is genetically determined: a study of normal twins. Diabetes 20030901
Dietary glycotoxins correlate with circulating advanced glycation end product levels in renal failure patients. American journal of kidney diseases : the official journal of the National Kidney Foundation 20030901
The breakdown of preexisting advanced glycation end products is associated with reduced renal fibrosis in experimental diabetes. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030901
Association between blood indoxyl sulfate and carbonyl stress marker in hemodialysis patients. Clinical nephrology 20030901
Production of N(epsilon)-(carboxymethyl)lysine is impaired in mice deficient in NADPH oxidase: a role for phagocyte-derived oxidants in the formation of advanced glycation end products during inflammation. Diabetes 20030801
Changes in glycation of fibrous type I collagen during long-term in vitro incubation with glucose. Journal of protein chemistry 20030801
In vitro glycoxidation of insoluble fibrous type I collagen: solubilization and advanced glycation end products. Journal of protein chemistry 20030801
Effect of smoking on risk factors for cardiovascular disease in patients with diabetes mellitus and renal insufficiency. European journal of medical research 20030731
The amino-terminal domains of the ezrin, radixin, and moesin (ERM) proteins bind advanced glycation end products, an interaction that may play a role in the development of diabetic complications. The Journal of biological chemistry 20030711
Impairment of vascular endothelial nitric oxide synthase activity by advanced glycation end products. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030701
Chronic diabetes increases advanced glycation end products on cardiac ryanodine receptors/calcium-release channels. Diabetes 20030701
Non-enzymatic glycation in corneas from normal and diabetic donors and its effects on epithelial cell attachment in vitro. Optometry (St. Louis, Mo.) 20030701
Fetal or neonatal low-glycotoxin environment prevents autoimmune diabetes in NOD mice. Diabetes 20030601
A role for advanced glycation end products in diminished bone healing in type 1 diabetes. Diabetes 20030601
Identification of N epsilon-(carboxyethyl)lysine, one of the methylglyoxal-derived AGE structures, in glucose-modified protein: mechanism for protein modification by reactive aldehydes. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030505
Changes in rat liver mitochondria with aging. Lon protease-like reactivity and N(epsilon)-carboxymethyllysine accumulation in the matrix. European journal of biochemistry 20030501
Increased levels of advanced glycation end products in human cataractous lenses. Journal of cataract and refractive surgery 20030501
Effects of ramipril in nondiabetic nephropathy: improved parameters of oxidatives stress and potential modulation of advanced glycation end products. Journal of human hypertension 20030401
Increased level of glycoxidation product N(epsilon)-(carboxymethyl)lysine in rat serum and urine proteins with aging: link with glycoxidative damage accumulation in kidney. Archives of biochemistry and biophysics 20030315
Restriction of dietary glycotoxins reduces excessive advanced glycation end products in renal failure patients. Journal of the American Society of Nephrology : JASN 20030301
Acute hyperglycemia causes intracellular formation of CML and activation of ras, p42/44 MAPK, and nuclear factor kappaB in PBMCs. Diabetes 20030301
Are advanced glycation end products cardiovascular risk factors in patients with CRF? American journal of kidney diseases : the official journal of the National Kidney Foundation 20030301
Formation of advanced glycation end products during CAPD. American journal of kidney diseases : the official journal of the National Kidney Foundation 20030301
An inhibitor of advanced glycation end product formation reduces N epsilon-(carboxymethyl)lysine accumulation in glomeruli of diabetic rats. American journal of kidney diseases : the official journal of the National Kidney Foundation 20030301
Graded sensitiveness of the various retinal neuron populations on the glyoxal-mediated formation of advanced glycation end products and ways of protection. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20030301
Comparative trial of N-acetyl-cysteine, taurine, and oxerutin on skin and kidney damage in long-term experimental diabetes. Diabetes 20030201
Increased serum levels of the specific AGE-compound methylglyoxal-derived hydroimidazolone in patients with type 2 diabetes. Metabolism: clinical and experimental 20030201
Serum levels of total homocysteine, homocysteine metabolites and of advanced glycation end-products (AGEs) in patients after renal transplantation. Clinical nephrology 20030201
N(carboxymethyl)lysine as a biomarker for microvascular complications in type 2 diabetic patients. Diabetes & metabolism 20030201
Advanced glycation end-products in anterior chamber aqueous of cataractous patients. Journal of cataract and refractive surgery 20030201
DNA damage by carbonyl stress in human skin cells. Mutation research 20030128
Effects of diabetes, insulin and antioxidants on NO synthase abundance and NO interaction with reactive oxygen species. Kidney international 20030101
Glucose degradation products in PD fluids: do they disappear from the peritoneal cavity and enter the systemic circulation? Kidney international 20030101
Pentosidine and N(epsilon)-(carboxymethyl)-lysine in Alzheimer's disease and vascular dementia. Neurobiology of aging 20030101
Relative quantification of N(epsilon)-(Carboxymethyl)lysine, imidazolone A, and the Amadori product in glycated lysozyme by MALDI-TOF mass spectrometry. Journal of agricultural and food chemistry 20030101
Serum levels of non-carboxymethyllysine advanced glycation endproducts are correlated to severity of microvascular complications in patients with Type 1 diabetes. Journal of diabetes and its complications 20030101
Relationship between plasma level of parathyroid hormone and carboxymethyllysine in hemodialyzed patients--does it exist? Clinical nephrology 20030101
Improvement in quality of diabetes control and concentrations of AGE-products in patients with type 1 and insulin-treated type 2 diabetes mellitus studied over a period of 10 years (JEVIN). Journal of diabetes and its complications 20030101
Effects of eparlestat on plasma levels of advanced glycation end products in patients with type 2 diabetes. In vivo (Athens, Greece) 20030101
Proteomic analysis of the site specificity of glycation and carboxymethylation of ribonuclease. Journal of proteome research 20030101
Calcification of the medial layer of the internal thoracic artery in diabetic patients: relevance of glycoxidation. Journal of vascular research 20030101
Photoaging and oxidative stress. Experimental dermatology 20030101
[Carbonyl stress significance in the pathogenesis of dialysis-related amyloidosis]. Przeglad lekarski 20030101
Identification in human atherosclerotic lesions of GA-pyridine, a novel structure derived from glycolaldehyde-modified proteins. The Journal of biological chemistry 20021213
Oxidative damage and phospholipid fatty acyl composition in skeletal muscle mitochondria from mice underexpressing or overexpressing uncoupling protein 3. The Biochemical journal 20021201
Renal connective tissue growth factor induction in experimental diabetes is prevented by aminoguanidine. Endocrinology 20021201
Activation of tubular epithelial cells in diabetic nephropathy. Diabetes 20021201
Alteration of the intracellular pH and apoptosis induction in a retinal cell line by the AGE-inducing agent glyoxal. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20021201
Contribution of superoxide to reduced antioxidant activity of glycoxidative serum albumin. Heart and vessels 20021101
Glycation by ascorbic acid causes loss of activity of ribulose-1,5-bisphosphate carboxylase/oxygenase and its increased susceptibility to proteases. Plant & cell physiology 20021101
Angiotensin II receptor antagonists and angiotensin-converting enzyme inhibitors lower in vitro the formation of advanced glycation end products: biochemical mechanisms. Journal of the American Society of Nephrology : JASN 20021001
Analysis of glycated and ascorbylated proteins by gas chromatography-mass spectrometry. Journal of agricultural and food chemistry 20020925
The AGE inhibitor pyridoxamine inhibits development of retinopathy in experimental diabetes. Diabetes 20020901
Peroxynitrite induces formation of N( epsilon )-(carboxymethyl) lysine by the cleavage of Amadori product and generation of glucosone and glyoxal from glucose: novel pathways for protein modification by peroxynitrite. Diabetes 20020901
Accumulation of imidazolone, pentosidine and N(epsilon)-(carboxymethyl)lysine in hippocampal CA4 pyramidal neurons of aged human brain. Pathology international 20020901
Oxidative, glycoxidative and lipoxidative damage to rat heart mitochondrial proteins is lower after 4 months of caloric restriction than in age-matched controls. Mechanisms of ageing and development 20020901
Immunolocalization and quantification of advanced glycation end products in retinal neovascular membranes and serum: a possible role in ocular neovascularization. Current eye research 20020901
Nepsilon-(Carboxymethyl)lysine induces gamma-glutamylcysteine synthetase in RAW264.7 cells. Biochemical and biophysical research communications 20020809
Lipid peroxidation and advanced glycation end products in the brain in normal aging and in Alzheimer's disease. Acta neuropathologica 20020801
Selective formation of certain advanced glycation end products in spinal cord astrocytes of humans and mice with superoxide dismutase-1 mutation. Acta neuropathologica 20020801
Photosensitized growth inhibition of cultured human skin cells: mechanism and suppression of oxidative stress from solar irradiation of glycated proteins. The Journal of investigative dermatology 20020801
N(epsilon)-Carboxymethyllysine in diabetic and non-diabetic polyneuropathies. Acta neuropathologica 20020701
Advanced glycation end products and mortality in hemodialysis patients. Kidney international 20020701
Identification of the advanced glycation end products N(epsilon)-carboxymethyllysine in the synovial tissue of patients with rheumatoid arthritis. Annals of the rheumatic diseases 20020601
Conversion of Amadori products of the Maillard reaction to N(epsilon)-(carboxymethyl)lysine by short-term heating: possible detection of artifacts by immunohistochemistry. Laboratory investigation; a journal of technical methods and pathology 20020601
Immunohistochemical demonstration of -(carboxymethyl)lysine protein adducts in normal and osteoarthritic cartilage. Histochemistry and cell biology 20020601
Detection of N epsilon-(carboxymethyl)lysine (CML) and non-CML advanced glycation end-products in the anterior horn of amyotrophic lateral sclerosis spinal cord. Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20020601
Assay of advanced glycation endproducts (AGEs): surveying AGEs by chromatographic assay with derivatization by 6-aminoquinolyl-N-hydroxysuccinimidyl-carbamate and application to Nepsilon-carboxymethyl-lysine- and Nepsilon-(1-carboxyethyl)lysine-modified albumin. The Biochemical journal 20020515
Chromatographic assay of glycation adducts in human serum albumin glycated in vitro by derivatization with 6-aminoquinolyl-N-hydroxysuccinimidyl-carbamate and intrinsic fluorescence. The Biochemical journal 20020515
Advanced glycation end product precursors impair epidermal growth factor receptor signaling. Diabetes 20020501
Lipid peroxidation and protein modification in a mouse model of chronic iron overload. Metabolism: clinical and experimental 20020501
Advanced glycation end products in children with chronic renal failure and type 1 diabetes. Pediatric nephrology (Berlin, Germany) 20020501
Reactive oxygen species accelerate production of vascular endothelial growth factor by advanced glycation end products in RAW264.7 mouse macrophages. Free radical biology & medicine 20020415
Marked increases in macrophage colony-stimulating factor and interleukin-18 in maintenance hemodialysis patients: comparative study of advanced glycation end products, carboxymethyllysine and pentosidine. Nephron 20020401
Advanced glycation end-products in corneas of patients with keratoconus. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20020401
Qualitative determination of specific protein glycation products by matrix-assisted laser desorption/ionization mass spectrometry Peptide mapping. Journal of agricultural and food chemistry 20020327
Hydroxynonenal adducts indicate a role for lipid peroxidation in neocortical and brainstem Lewy bodies in humans. Neuroscience letters 20020208
Markedly elevated levels of plasma advanced glycation end products in patients with liver cirrhosis - amelioration by liver transplantation. Journal of hepatology 20020101
Effect of heat-treated proteins on selected parameters of the biotransformation system in the rat. Annals of nutrition & metabolism 20020101
Aging increases Nepsilon-(carboxymethyl)lysine and caloric restriction decreases Nepsilon-(carboxyethyl)lysine and Nepsilon-(malondialdehyde)lysine in rat heart mitochondrial proteins. Free radical research 20020101
N epsilon-(carboxymethyl)lysine (CML) as a biomarker of oxidative stress in long-lived tissue proteins. Methods in molecular biology (Clifton, N.J.) 20020101
Hormetic action of mild heat stress decreases the inducibility of protein oxidation and glycoxidation in human fibroblasts. Biogerontology 20020101
Advanced glycation end products and nutrition. Physiological research 20020101
Serum N-epsilon-(carboxymethyl)lysine is elevated in nondiabetic coronary heart disease patients. Journal of basic and clinical physiology and pharmacology 20020101
Chelating activity of advanced glycation end-product inhibitors. The Journal of biological chemistry 20011228
Glyoxalase I deficiency is associated with an unusual level of advanced glycation end products in a hemodialysis patient. Kidney international 20011201
Plasma levels of advanced glycation end products in children with renal disease. Pediatric nephrology (Berlin, Germany) 20011201
Plasma levels of advanced glycation end products in healthy, long-term vegetarians and subjects on a western mixed diet. European journal of nutrition 20011201
Receptor for advanced glycation end products, inflammation, and accelerated periodontal disease in diabetes: mechanisms and insights into therapeutic modalities. Annals of periodontology 20011201
Advanced glycation end products in Descemet's membrane and their effect on corneal endothelial cell. Current eye research 20011201
RAGE expression and AGE-induced MAP kinase activation in Caco-2 cells. Biochemical and biophysical research communications 20011116
Amides are novel protein modifications formed by physiological sugars. The Journal of biological chemistry 20011109
Potential value of CML-Hb in predicting the progression of bone cysts in dialysis-related amyloidosis. Nephron 20011101
Glycoxidation-modified macrophages and lipid peroxidation products are associated with the progression of human diabetic nephropathy. American journal of kidney diseases : the official journal of the National Kidney Foundation 20011101
Cytoprotective role of heme oxygenase (HO)-1 in human kidney with various renal diseases. Kidney international 20011101
Conformational study of N(epsilon)-(carboxymethyl)lysine adducts of recombinant gammaC-crystallin. Journal of protein chemistry 20011101
N(epsilon)-(carboxymethyl)lysine levels in patients with type 2 diabetes: role of renal function. American journal of kidney diseases : the official journal of the National Kidney Foundation 20011001
Isotope dilution gas chromatography/mass spectrometry method for the determination of methionine sulfoxide in protein. Analytical chemistry 20011001
Sunlight induces N epsilon-(carboxymethyl)lysine formation from glycated polylysine-iron(III) complex. Photochemistry and photobiology 20010901
Active glycation in neurofibrillary pathology of Alzheimer disease: N(epsilon)-(carboxymethyl) lysine and hexitol-lysine. Free radical biology & medicine 20010715
Alternative routes for the formation of immunochemically distinct advanced glycation end-products in vivo. Current molecular medicine 20010701
[Increased levels of circulating advanced glycation end products in a model of acute renal insufficiency in rats]. Casopis lekaru ceskych 20010621
Requirement for p38 and p44/p42 mitogen-activated protein kinases in RAGE-mediated nuclear factor-kappaB transcriptional activation and cytokine secretion. Diabetes 20010601
Immunohistochemical distribution and quantitative biochemical detection of advanced glycation end products in fetal to adult rats and in rats with streptozotocin-induced diabetes. Laboratory investigation; a journal of technical methods and pathology 20010601
Oxidative stress and increased expression of growth factors in lesions of failed hemodialysis access. American journal of kidney diseases : the official journal of the National Kidney Foundation 20010501
Carboxymethyllysine in dermal tissues of diabetic and nondiabetic patients with chronic renal failure: relevance to glycoxidation damage. Nephron 20010501
Increased levels of vascular endothelial growth factor and advanced glycation end products in aqueous humor of patients with diabetic retinopathy. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20010501
The AGE product N epsilon-(carboxymethyl)lysine serum albumin is a modulator of proteoglycan expression in polarized cultured kidney epithelial cells. Diabetologia 20010401
Formation of advanced glycation end-product-modified superoxide dismutase-1 (SOD1) is one of the mechanisms responsible for inclusions common to familial amyotrophic lateral sclerosis patients with SOD1 gene mutation, and transgenic mice expressing human SOD1 gene mutation. Neuropathology : official journal of the Japanese Society of Neuropathology 20010301
In vitro formation of N(epsilon)-(carboxymethyl)lysine and imidazolones under conditions similar to continuous ambulatory peritoneal dialysis. Biochemical and biophysical research communications 20010209
Glycoxidation and lipid peroxidation of low-density lipoprotein can synergistically enhance atherogenesis. Cardiovascular research 20010201
3-deoxyglucosone and AGEs in uremic complications: inactivation of glutathione peroxidase by 3-deoxyglucosone. Kidney international. Supplement 20010201
Circulating advanced glycation end product levels in rats rapidly increase with acute renal failure. Kidney international. Supplement 20010201
Dialysis-related amyloidosis of the heart in long-term hemodialysis patients. Kidney international. Supplement 20010201
Evidence for non-enzymatic glycosylation in Escherichia coli. Molecular microbiology 20010201
Neuronal and glial advanced glycation end product [Nepsilon-(carboxymethyl)lysine]] in Alzheimer's disease brains. Acta neuropathologica 20010101
Dialysis-related amyloidosis: pathogenesis focusing on AGE modification. Seminars in dialysis 20010101
Immunochemical assay of hemoglobin with N(epsilon)-(carboxymethyl)lysine at lysine 66 of the beta chain. Clinical chemistry 20010101
Efficacy of benfotiamine versus thiamine on function and glycation products of peripheral nerves in diabetic rats. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20010101
Nonoxidative protein glycation is implicated in familial amyotrophic lateral sclerosis with superoxide dismutase-1 mutation. Acta neuropathologica 20000901
Immunological evidence for methylglyoxal-derived modifications in vivo. Determination of antigenic epitopes. The Journal of biological chemistry 19980320
N (epsilon)-(carboxymethyl)lysine protein adduct is a major immunological epitope in proteins modified with advanced glycation end products of the Maillard reaction. Biochemistry 19960618
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