Tiazofurine
| Title | Journal |
|---|---|
| Synthesis and in vitro antitumour screening of 2-(β-D-xylofuranosyl)thiazole-4-carboxamide and two novel tiazofurin analogues with substituted tetrahydrofurodioxol moiety as a sugar mimic. | Bioorganic & medicinal chemistry letters 20121101 |
| Novel synthetic route to the C-nucleoside, 2-deoxy benzamide riboside. | Bioorganic & medicinal chemistry letters 20120815 |
| Synthesis of novel aza-analogues of tiazofurin with 2-[5,5-bis(hydroxymethyl)pyrrolidin-2-yl] framework as sugar mimic. | Nucleosides, nucleotides & nucleic acids 20120101 |
| Identification of novel Mt-Guab2 inhibitor series active against M. tuberculosis. | PloS one 20120101 |
| Antileukemic Potential of Momordica charantia Seed Extracts on Human Myeloid Leukemic HL60 Cells. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
| 4-Pyridone-3-carboxamide-1-β-D-ribonucleoside triphosphate (4PyTP), a novel NAD metabolite accumulating in erythrocytes of uremic children: a biomarker for a toxic NAD analogue in other tissues? | Toxins 20110601 |
| NMNAT expression and its relation to NAD metabolism. | Current medicinal chemistry 20110101 |
| A very rapid visual recovery of posterior reversible encephalopathy syndrome. | Journal of clinical imaging science 20110101 |
| Proteomic analysis of endothelial cold-adaptation. | BMC genomics 20110101 |
| Induction of cytoplasmic rods and rings structures by inhibition of the CTP and GTP synthetic pathway in mammalian cells. | PloS one 20110101 |
| Microwave-assisted Heterocyclic Dicarboxylic Acids as Potential Antifungal and Antibacterial Drugs. | Indian journal of pharmaceutical sciences 20110101 |
| New trends in nucleoside biotechnology. | Acta naturae 20100701 |
| Multifactorial anticancer effects of digalloyl-resveratrol encompass apoptosis, cell-cycle arrest, and inhibition of lymphendothelial gap formation in vitro. | British journal of cancer 20100427 |
| Overexpression of inosine 5'-monophosphate dehydrogenase type II mediates chemoresistance to human osteosarcoma cells. | PloS one 20100101 |
| A comparative profile of methanol extracts of Allium cepa and Allium sativum in diabetic neuropathy in mice. | Pharmacognosy research 20100101 |
| Selective inhibition of nicotinamide adenine dinucleotide kinases by dinucleoside disulfide mimics of nicotinamide adenine dinucleotide analogues. | Bioorganic & medicinal chemistry 20090801 |
| Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. | Journal of medicinal chemistry 20081113 |
| Ribavirin targets eIF4E dependent Akt survival signaling. | Biochemical and biophysical research communications 20081024 |
| A kinetic alignment of orthologous inosine-5'-monophosphate dehydrogenases. | Biochemistry 20080819 |
| Bis(sulfonamide) isosters of mycophenolic adenine dinucleotide analogues: inhibition of inosine monophosphate dehydrogenase. | Bioorganic & medicinal chemistry 20080801 |
| Therapeutic effects of combined treatment with ribavirin and tiazofurin on experimental autoimmune encephalomyelitis development: clinical and histopathological evaluation. | Journal of the neurological sciences 20080415 |
| Treatment of yellow fever. | Antiviral research 20080401 |
| Probing binding requirements of type I and type II isoforms of inosine monophosphate dehydrogenase with adenine-modified nicotinamide adenine dinucleotide analogues. | Journal of medicinal chemistry 20071115 |
| Nicotinamide riboside kinase structures reveal new pathways to NAD+. | PLoS biology 20071001 |
| Synthesis and antitumour activity of new tiazofurin analogues bearing a 2,3-anhydro functionality in the furanose ring. | Bioorganic & medicinal chemistry letters 20070801 |
| Crystal structure of human nicotinamide riboside kinase. | Structure (London, England : 1993) 20070801 |
| Recent development of IMP dehydrogenase inhibitors for the treatment of cancer. | Current opinion in drug discovery & development 20070701 |
| Antiviral activity of tiazofurin and mycophenolic acid against Grapevine leafroll-associated virus 3 in Vitis vinifera explants. | Antiviral research 20070301 |
| Organosilicon-containing thiazole derivatives as potential lipoxygenase inhibitors and anti-inflammatory agents. | Bioinorganic chemistry and applications 20070101 |
| 2-(3-Amino-3-deoxy-beta-D-xylofuranosyl)thiazole-4-carboxamide: a new tiazofurin analogue with potent antitumour activity. | Bioorganic & medicinal chemistry letters 20061015 |
| Synthesis and antiproliferative activity of two new tiazofurin analogues with 2'-amido functionalities. | Bioorganic & medicinal chemistry letters 20060515 |
| Synthesis and biological activity of some new 5'-O-acyl tiazofurin derivatives. | European journal of medicinal chemistry 20060401 |
| Metabolic regulation and chemotherapy. | Advances in enzyme regulation 20060101 |
| Modulation of cancer pathways by inhibitors of guanylate metabolism. | Advances in enzyme regulation 20060101 |
| Resveratrol, an ingredient of wine, acts synergistically with Ara-C and tiazofurin in HL-60 human promyelocytic leukemia cells. | Nucleosides, nucleotides & nucleic acids 20060101 |
| Zinc(II) triflate-controlled 1,3-dipolar cycloadditions of C-(2-thiazolyl)nitrones: application to the synthesis of a novel isoxazolidinyl analogue of tiazofurin. | The Journal of organic chemistry 20051028 |
| Efficient route to C2 symmetric heterocyclic backbone modified cyclic peptides. | Organic letters 20050929 |
| Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure. | Journal of pharmaceutical sciences 20050701 |
| IMP dehydrogenase from the protozoan parasite Toxoplasma gondii. | Antimicrobial agents and chemotherapy 20050601 |
| Combination of nucleoside analogues tiazofurin and ribavirin downregulates experimental autoimmune encephalomyelitis. | Annals of the New York Academy of Sciences 20050601 |
| Synergistic action of resveratrol, an ingredient of wine, with Ara-C and tiazofurin in HL-60 human promyelocytic leukemia cells. | Experimental hematology 20050301 |
| Metabolism and antiviral activity of ribavirin. | Virus research 20050201 |
| Role of human nucleoside transporters in the cellular uptake of two inhibitors of IMP dehydrogenase, tiazofurin and benzamide riboside. | Molecular pharmacology 20050101 |
| Sensitization of human erythroleukemia K562 cells resistant to methotrexate by inhibiting IMPDH. | Medical science monitor : international medical journal of experimental and clinical research 20050101 |
| Down-regulation of increased signal transduction capacity in human cancer cells. | Advances in enzyme regulation 20050101 |
| Synthesis of 3'-deoxy-3'-C-hydroxymethyl analogues of tiazofurin and ribavirin. | Nucleosides, nucleotides & nucleic acids 20050101 |
| Differentiation of human prostate cancer PC-3 cells induced by inhibitors of inosine 5'-monophosphate dehydrogenase. | Cancer research 20041215 |
| Inhibition of B16 mouse melanoma cell growth and induction of apoptotic cell death with 8-chloroadenosine-3',5'-monophosphate and tiazofurin. | Annals of the New York Academy of Sciences 20041201 |
| Effects of the IMP-dehydrogenase inhibitor, Tiazofurin, in bcr-abl positive acute myelogenous leukemia. Part I. In vivo studies. | Leukemia research 20041101 |
| Effects of the IMP-dehydrogenase inhibitor, Tiazofurin, in bcr-abl positive acute myelogenous leukemia. Part II. In vitro studies. | Leukemia research 20041101 |
| Cryptosporidium parvum IMP dehydrogenase: identification of functional, structural, and dynamic properties that can be exploited for drug design. | The Journal of biological chemistry 20040924 |
| Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans. | Cell 20040514 |
| Substitution of the conserved Arg-Tyr dyad selectively disrupts the hydrolysis phase of the IMP dehydrogenase reaction. | Biochemistry 20040420 |
| A simple assay for determining antiviral activity against Crimean-Congo hemorrhagic fever virus. | Antiviral research 20040401 |
| Cofactor mimics as selective inhibitors of NAD-dependent inosine monophosphate dehydrogenase (IMPDH)--the major therapeutic target. | Current medicinal chemistry 20040401 |
| The effects of tiazofurin on basal and amphetamine-induced motor activity in rats. | Pharmacology, biochemistry, and behavior 20040301 |
| Erythrocytotoxicity of tiazofurin in vivo and in vitro detected by scanning probe microscopy. | Toxicology letters 20040202 |
| Anticancer therapeutic potential of soy isoflavone, genistein. | Advances in experimental medicine and biology 20040101 |
| HPLC determination of tiazofurin in the rat brain. | Journal of pharmaceutical and biomedical analysis 20031124 |
| Synthesis of 2-(3'-azido- and 3'-amino-3'-deoxy-beta-D-ribofuranosyl)thiazole-4-carboxamide. | Nucleosides, nucleotides & nucleic acids 20031101 |
| De novo synthesis of two new cytotoxic tiazofurin analogues with modified sugar moieties. | Bioorganic & medicinal chemistry letters 20031006 |
| In vitro sensitivity of hematopoietic progenitors to tiazofurin in refractory acute myeloid leukemia and in the blast crisis of chronic myeloid leukemia. | Cancer letters 20030610 |
| Combination therapy in childhood leukaemia: in vitro studies of thiopurines and inhibitors of purine metabolism on apoptosis. | Annals of clinical biochemistry 20030101 |
| Potential antiviral therapeutics for smallpox, monkeypox and other orthopoxvirus infections. | Antiviral research 20030101 |
| [IMP dehydrogenase]. | Nihon rinsho. Japanese journal of clinical medicine 20030101 |
| Targeting signal transduction. | Advances in enzyme regulation 20030101 |
| A new tiazofurin pronucleotide: synthesis and biological evaluation of cyclosaligenyl-tiazofurin monophosphate. | Nucleosides, nucleotides & nucleic acids 20030101 |
| The linkage of glucose to tiazofurin decreases in vitro uptake into rat glioma C6 cells. | Journal of drug targeting 20021201 |
| Simultaneous LC determination of tiazofurin, its acetyl and benzoyl esters and their active metabolite thiazole-4-carboxamide adenine dinucleotide in biological samples. | Journal of pharmaceutical and biomedical analysis 20021107 |
| Inhibitors of the IMPDH enzyme as potential anti-bovine viral diarrhoea virus agents. | Antiviral chemistry & chemotherapy 20021101 |
| Down-regulation of experimental allergic encephalomyelitis in DA rats by tiazofurin. | Journal of neuroimmunology 20020901 |
| Cytoprotective features of selenazofurin in hematopoietic cells. | International journal of clinical pharmacology and therapeutics 20020801 |
| Cytotoxicity and cellular differentiation activity of methylenebis(phosphonate) analogs of tiazofurin and mycophenolic acid adenine dinucleotide in human cancer cell lines. | Cancer letters 20020708 |
| Identification of active antiviral compounds against a New York isolate of West Nile virus. | Antiviral research 20020701 |
| Structure of human nicotinamide/nicotinic acid mononucleotide adenylyltransferase. Basis for the dual substrate specificity and activation of the oncolytic agent tiazofurin. | The Journal of biological chemistry 20020412 |
| The chemistry of nicotinamide adenine dinucleotide (NAD) analogues containing C-nucleosides related to nicotinamide riboside. | Current medicinal chemistry 20020401 |
| Studies on the mechanism of action of benzamide riboside: a novel inhibitor of IMP dehydrogenase. | Current medicinal chemistry 20020401 |
| Modulation of cytotoxicity of benzamide riboside by expression of NMN adenylyltransferase. | Current medicinal chemistry 20020401 |
| Benzamide riboside, a recent inhibitor of inosine 5'-monophosphate dehydrogenase induces transferrin receptors in cancer cells. | Current medicinal chemistry 20020401 |
| Metabolism of the novel IMP dehydrogenase inhibitor benzamide riboside. | Current medicinal chemistry 20020401 |
| Toxicity and efficacy of benzamide riboside in cancer chemotherapy models. | Current medicinal chemistry 20020401 |
| Novel mycophenolic adenine bis(phosphonate) analogues as potential differentiation agents against human leukemia. | Journal of medicinal chemistry 20020131 |
| [Application of tiazofurin in the study of regulation of AMP deaminase in intact malignant cells]. | Glas. Srpska akademija nauka i umetnosti. Odeljenje medicinskih nauka 20020101 |
| Ordered biochemical program of gene expression in cancer cells. | Biochemistry. Biokhimiia 20011001 |
| Induction of Tmolt4 leukemia cell death by 3,3-disubstituted-6,6-pentamethylene-1,5-diazabicyclo[3.1.0]hexane-2-4-diones: specificity for type II inosine 5'-monophasphate dehydrogenase. | The Journal of pharmacology and experimental therapeutics 20010801 |
| Vaccinia virus inhibitors as a paradigm for the chemotherapy of poxvirus infections. | Clinical microbiology reviews 20010401 |
| Tumor cell-specific inhibition of inducible nitric oxide synthase activation by tiazofurin. | International immunopharmacology 20010401 |
| A new C-nucleoside analogue of tiazofurin: synthesis and biological evaluation of 2-beta-D-ribofuranosylimidazole-4-carboxamide (imidazofurin). | Bioorganic & medicinal chemistry letters 20010108 |
| Sir Hans A. Krebs Centenary Lecture: cancer and clinical targeting. | Advances in enzyme regulation 20010101 |
| A new synthetic methodology for tiazofurin. | Nucleosides, nucleotides & nucleic acids 20010101 |
| Hematological toxicity associated with tiazofurin-influence on erythropoiesis. | Toxicology letters 20000403 |
| Nucleoside and non-nucleoside IMP dehydrogenase inhibitors as antitumor and antiviral agents. | Current medicinal chemistry 19990701 |
| Regulation of the signal transduction program by drugs. | Advances in enzyme regulation 19970101 |
| Tiazofurin: molecular and clinical action. | Anticancer research 19960101 |
| Antiviral and immunomodulating inhibitors of experimentally-induced Punta Toro virus infections. | Antiviral research 19941001 |
| Novobiocin-induced anti-proliferative and differentiating effects in melanoma B16. | British journal of cancer 19920201 |
| Inhibitors of IMP dehydrogenase stimulate the phosphorylation of the antiviral nucleoside 2' ,3'-dideoxyguanosine. | Biochemical and biophysical research communications 19900928 |
| Clinical toxicity associated with tiazofurin. | Investigational new drugs 19900501 |
| Reversible cerebral lesions associated with tiazofurin usage: MR demonstration. | Journal of computer assisted tomography 19880101 |
| Phase I trial of tiazofurin administered by i.v. bolus daily for 5 days, with pharmacokinetic evaluation. | Cancer treatment reports 19870201 |
| Synergistic antiviral effects of ribavirin and the C-nucleoside analogs tiazofurin and selenazofurin against togaviruses, bunyaviruses, and arenaviruses. | Antimicrobial agents and chemotherapy 19841001 |
| Broad-spectrum antiviral activity of 2-beta-D-ribofuranosylselenazole-4-carboxamide, a new antiviral agent. | Antimicrobial agents and chemotherapy 19830901 |