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H-Ser(so3h)-oh

CAS No.:
626-69-7
Catalog Number:
AG00EC7J
Molecular Formula:
Molecular Weight:
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
250mg
≥ 101% (Assay)
1 week
United States
$177
- +
1g
≥ 101% (Assay)
1 week
United States
$316
- +
Product Description
Catalog Number:
AG00EC7J
Chemical Name:
H-Ser(so3h)-oh
CAS Number:
626-69-7
MDL Number:
MFCD00672378
IUPAC Name:
(2S)-2-amino-3-sulfooxypropanoic acid
InChI:
InChI=1S/C3H7NO6S/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H,7,8,9)/t2-/m0/s1
InChI Key:
LFZGUGJDVUUGLK-REOHCLBHSA-N
UNII:
81K4VO7FNP
Properties
Complexity:
227  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0
Exact Mass:
184.999g/mol
Formal Charge:
0
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
185.15g/mol
Monoisotopic Mass:
184.999g/mol
Rotatable Bond Count:
4  
Topological Polar Surface Area:
135A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-4.4  
Literature
Title Journal
Antinociceptive effect of rat D-serine racemase inhibitors, L-serine-O-sulfate, and L-erythro-3-hydroxyaspartate in an arthritic pain model. TheScientificWorldJournal 20120101
3-Phosphono-L-alanine as pyrophosphate mimic for DNA synthesis using HIV-1 reverse transcriptase. Organic & biomolecular chemistry 20110107
Functional roles of high-affinity glutamate transporters in cochlear afferent synaptic transmission in the mouse. Journal of neurophysiology 20100501
Conformationally-restricted amino acid analogues bearing a distal sulfonic acid show selective inhibition of system x(c)(-) over the vesicular glutamate transporter. Bioorganic & medicinal chemistry letters 20100415
Inhibition of glutamate transporters couples to Kv4.2 dephosphorylation through activation of extrasynaptic NMDA receptors. Neuroscience 20100113
Discovery of the first selective inhibitor of excitatory amino acid transporter subtype 1. Journal of medicinal chemistry 20090226
Purification and characterization of human brain serine racemase expressed in moderately halophilic bacteria. Protein and peptide letters 20090101
Riluzole enhances the activity of glutamate transporters GLAST, GLT1 and EAAC1. European journal of pharmacology 20080114
Molecular modeling and docking studies of glutamate racemase in Vibrio vulnificus CMCP6. In silico biology 20080101
Comparison of [(3)H]-(2S,4R)-4-methylglutamate and [(3)H]D-aspartate as ligands for binding and autoradiographic analyses of glutamate transporters. Neurochemistry international 20071201
Structural insight into the pharmacophore pocket of human glutamate carboxypeptidase II. Journal of medicinal chemistry 20070712
Human glutamate carboxypeptidase II inhibition: structures of GCPII in complex with two potent inhibitors, quisqualate and 2-PMPA. Acta crystallographica. Section D, Biological crystallography 20070401
Impact of the gliotoxin L-serine-O-sulphate on cellular metabolism in cultured rat astrocytes. Neurochemistry international 20060601
Dual substrate and reaction specificity in mouse serine racemase: identification of high-affinity dicarboxylate substrate and inhibitors and analysis of the beta-eliminase activity. Biochemistry 20051004
Substrate-induced modulation of glutamate uptake in human platelets. British journal of pharmacology 20050701
Regulation of serine racemase activity by amino acids. Brain research. Molecular brain research 20050218
Gliotoxins disrupt alanine metabolism and glutathione production in C6 glioma cells: a 13C NMR spectroscopic study. Neurochemistry international 20041201
Binding and transport of [3H](2S,4R)- 4-methylglutamate, a new ligand for glutamate transporters, demonstrate labeling of EAAT1 in cultured murine astrocytes. Journal of neuroscience research 20040315
Differentiation of substrate and non-substrate inhibitors of transport system xc(-): an obligate exchanger of L-glutamate and L-cystine. Neuropharmacology 20040201
Theanine and glutamate transporter inhibitors enhance the antitumor efficacy of chemotherapeutic agents. Biochimica et biophysica acta 20031205
An NMR study of alterations in [1-13C]glucose metabolism in C6 glioma cells by gliotoxic amino acids. Neurochemistry international 20030501
The 'glial' glutamate transporter, EAAT2 (Glt-1) accounts for high affinity glutamate uptake into adult rodent nerve endings. Journal of neurochemistry 20030201
Effects of glutamate transporter inhibitors on the antitumor activity of doxorubicin. Clinical cancer research : an official journal of the American Association for Cancer Research 20021201
Allosteric regulation of mouse brain serine racemase. Neurochemical research 20021201
Molecular mechanisms of cystine transport. Biochemical Society transactions 20011101
Characterization of Na+-coupled glutamate/aspartate transport by a rat brain astrocyte line expressing GLAST and EAAC1. The Journal of membrane biology 20010701
[(3)H](2S,4R)-4-Methylglutamate: a novel ligand for the characterization of glutamate transporters. Journal of neurochemistry 20010601
A Na+-dependent electrogenic glutamate transporter current in voltage-clamped cells of corpora allata in the cricket Gryllus bimaculatus. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20010501
Properties