(8R,9S,13S,14S,16R)-3,16-Dihydroxy-13-methyl-7,8,9,11,12,13,15,16-octahydro-6H-cyclopenta[a]phenanthren-17(14H)-one
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The relation of urinary estrogen metabolites with mammographic densities in premenopausal women. | Cancer epidemiology 20121001 |
Association between physical activity and urinary estrogens and estrogen metabolites in premenopausal women. | The Journal of clinical endocrinology and metabolism 20121001 |
Urinary estrogen metabolites in two soy trials with premenopausal women. | European journal of clinical nutrition 20120901 |
Activity of the estrogen-metabolizing enzyme cytochrome P450 1B1 influences the development of pulmonary arterial hypertension. | Circulation 20120828 |
Estrogen metabolism and autoimmunity. | Autoimmunity reviews 20120501 |
Urinary estrogen metabolites during a randomized soy trial. | Nutrition and cancer 20120201 |
Analysis of multiplex endogenous estrogen metabolites in human urine using ultra-fast liquid chromatography-tandem mass spectrometry: a case study for breast cancer. | Analytica chimica acta 20120120 |
Anti-proliferative effects of Chinese herb Cornus officinalis in a cell culture model for estrogen receptor-positive clinical breast cancer. | Molecular medicine reports 20120101 |
Postmenopausal circulating levels of 2- and 16α-hydroxyestrone and risk of endometrial cancer. | British journal of cancer 20111025 |
The effect of tamoxifen and raloxifene on estrogen metabolism and endometrial cancer risk. | The Journal of steroid biochemistry and molecular biology 20110901 |
Liquid chromatography/mass spectrometry of pre-ionized Girard P derivatives for quantifying estrone and its metabolites in serum from postmenopausal women. | Rapid communications in mass spectrometry : RCM 20110515 |
3,3'-diindolylmethane modulates estrogen metabolism in patients with thyroid proliferative disease: a pilot study. | Thyroid : official journal of the American Thyroid Association 20110301 |
Dietary fiber and serum 16α-hydroxyestrone, an estrogen metabolite associated with lower systolic blood pressure. | Nutrition (Burbank, Los Angeles County, Calif.) 20110101 |
Estrogen metabolite ratio: Is the 2-hydroxyestrone to 16α-hydroxyestrone ratio predictive for breast cancer? | International journal of women's health 20110101 |
Coffee consumption and risk of cancers: a meta-analysis of cohort studies. | BMC cancer 20110101 |
A preliminary study of the effectiveness of chinese therapeutic food on regulating female reproductive hormones. | Integrative medicine insights 20110101 |
The role of female hormones on lung function in chronic lung diseases. | BMC women's health 20110101 |
Serum concentrations of selected endogenous estrogen and estrogen metabolites in pre- and post-menopausal Chinese women with osteoarthritis. | Journal of endocrinological investigation 20101001 |
A new approach to measuring estrogen exposure and metabolism in epidemiologic studies. | The Journal of steroid biochemistry and molecular biology 20100801 |
Comparison of liquid chromatography-tandem mass spectrometry, RIA, and ELISA methods for measurement of urinary estrogens. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20100101 |
Effect of flaxseed consumption on urinary levels of estrogen metabolites in postmenopausal women. | Nutrition and cancer 20100101 |
Effects of a breast-health herbal formula supplement on estrogen metabolism in pre- and post-menopausal women not taking hormonal contraceptives or supplements: a randomized controlled trial. | Breast cancer : basic and clinical research 20100101 |
Serum estrogen metabolites and systolic blood pressure among middle-aged and older women and men. | American journal of hypertension 20091101 |
Estrone/17beta-estradiol conversion to, and tumor necrosis factor inhibition by, estrogen metabolites in synovial cells of patients with rheumatoid arthritis and patients with osteoarthritis. | Arthritis and rheumatism 20091001 |
Urinary estrogen metabolites in women at high risk for breast cancer. | Carcinogenesis 20090901 |
Circulating estrogen metabolites and risk for breast cancer in premenopausal women. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20090801 |
Ethnicity, body size, and estrogen levels in postmenopausal Hispanic and non-Hispanic white women. | Journal of women's health (2002) 20090401 |
An improved method for the simultaneous analysis of phenolic and steroidal estrogens in water and sediment. | Talanta 20090215 |
Estrogen hydroxylation--the good and the bad. | Annals of the New York Academy of Sciences 20090201 |
16alpha-hydroxyestrone inhibits estrogen sulfotransferase activity in human liver cancer cells. | Annals of the New York Academy of Sciences 20090201 |
Lycium barbarum inhibits growth of estrogen receptor positive human breast cancer cells by favorably altering estradiol metabolism. | Nutrition and cancer 20090101 |
Urinary estrogen metabolites and prostate cancer: a case-control study and meta-analysis. | Journal of experimental & clinical cancer research : CR 20090101 |
Daidzein-metabolizing phenotypes in relation to serum hormones and sex hormone binding globulin, and urinary estrogen metabolites in premenopausal women in the United States. | Cancer causes & control : CCC 20081201 |
Coffee intake and CYP1A2*1F genotype predict breast volume in young women: implications for breast cancer. | British journal of cancer 20081104 |
Fat/fiber intakes and sex hormones in healthy premenopausal women in USA. | The Journal of steroid biochemistry and molecular biology 20081101 |
Levels of sex steroid and cardiovascular disease measures in premenopausal and hormone-treated women at midlife: implications for the 'timing hypothesis'. | Archives of internal medicine 20081027 |
Past oral contraceptive use and current dietary soy isoflavones influence estrogen metabolism in postmenopausal monkeys (Macaca fascicularis). | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20081001 |
Circulating 2-hydroxy- and 16alpha-hydroxy estrone levels and risk of breast cancer among postmenopausal women. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20080801 |
Oestrogen metabolites in relation to isoprostanes as a measure of oxidative stress. | Clinical endocrinology 20080501 |
Involvement of peroxiredoxin IV in the 16alpha-hydroxyestrone-induced proliferation of human MCF-7 breast cancer cells. | Cell biology international 20080401 |
Phytoestrogens and breast cancer prevention: possible mechanisms of action. | Environmental health perspectives 20080401 |
Exercise effect on oxidative stress is independent of change in estrogen metabolism. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20080101 |
Development and statistical validation of a quantitative method for the determination of steroid hormones in environmental water by column liquid chromatography/tandem mass spectrometry. | Journal of AOAC International 20080101 |
Evaluation of electrospray ionization and atmospheric pressure chemical ionization for simultaneous detection of estrone and its metabolites using high-performance liquid chromatography/tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071201 |
A pilot and feasibility study on the effects of naturopathic botanical and dietary interventions on sex steroid hormone metabolism in premenopausal women. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20070801 |
The effects of soygerm extracts on blood lipoproteins, antioxidative capacity and urinary estrogen metabolites in postmenopausal women on hormone therapy. | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20070701 |
Breast cancer: are oestrogen metabolites carcinogenic? | Maturitas 20070520 |
Soy isoflavonoid effects on endogenous estrogen metabolism in postmenopausal female monkeys. | Carcinogenesis 20070401 |
Effects of aerobic exercise training on estrogen metabolism in premenopausal women: a randomized controlled trial. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20070401 |
Variants in estrogen metabolism and biosynthesis genes and urinary estrogen metabolites in women with a family history of breast cancer. | Breast cancer research and treatment 20070301 |
Urinary phytoestrogen excretion of rats bearing methylnitrosourea-induced mammary carcinoma in response to treatment with 2-methoxyestradiol. | The Journal of steroid biochemistry and molecular biology 20070201 |
Changes in 2-hydroxyestrone and 16alpha-hydroxyestrone metabolism with flaxseed consumption: modification by COMT and CYP1B1 genotype. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20070201 |
Enhanced NF kappa B and AP-1 transcriptional activity associated with antiestrogen resistant breast cancer. | BMC cancer 20070101 |
In vitro short-term test evaluation of catecholestrogens genotoxicity. | The Journal of steroid biochemistry and molecular biology 20070101 |
Soy isoflavone intake and estrogen excretion patterns in young women: effect of probiotic administration. | In vivo (Athens, Greece) 20070101 |
Moderate coffee and alcohol consumption improves the estrogen metabolite profile in adjuvant treated breast cancer patients: a pilot study comparing pre- and post-operative levels. | Molecular genetics and metabolism 20061201 |
Estrogens and autoimmune diseases. | Annals of the New York Academy of Sciences 20061101 |
CYP1A1 and CYP1B1 polymorphisms and their association with estradiol and estrogen metabolites in women who are premenopausal and perimenopausal. | The American journal of medicine 20060901 |
Optimisation of derivatisation for the analysis of estrogenic compounds in water by solid-phase extraction gas chromatography-mass spectrometry. | Analytica chimica acta 20060901 |
Estradiol and its metabolites and their association with knee osteoarthritis. | Arthritis and rheumatism 20060801 |
Selected diet and lifestyle factors are associated with estrogen metabolites in a multiracial/ethnic population of women. | The Journal of nutrition 20060601 |
A hormonal association between estrogen metabolism and proliferative thyroid disease. | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20060601 |
Comparison of possible carcinogenic estradiol metabolites: effects on proliferation, apoptosis and metastasis of human breast cancer cells. | Maturitas 20060420 |
Obesity, hormone therapy, estrogen metabolism and risk of postmenopausal breast cancer. | International journal of cancer 20060301 |
Effects of docosahexaenoic acid supplementation on blood lipids, estrogen metabolism, and in vivo oxidative stress in postmenopausal vegetarian women. | European journal of clinical nutrition 20060301 |
Estrogen metabolites and systolic blood pressure in a population-based sample of postmenopausal women. | The Journal of clinical endocrinology and metabolism 20060301 |
Analysis of fifteen estrogen metabolites using packed column supercritical fluid chromatography-mass spectrometry. | Analytical chemistry 20060301 |
Role of polymorphic human cytochrome P450 enzymes in estrone oxidation. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20060301 |
Comparison of plasma and urinary levels of 2-hydroxyestrogen and 16 alpha-hydroxyestrogen metabolites. | Molecular genetics and metabolism 20060201 |
Estrogen metabolism and breast cancer. | Epidemiology (Cambridge, Mass.) 20060101 |
A randomized phase II trial of indole-3-carbinol in the treatment of vulvar intraepithelial neoplasia. | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20060101 |
Mitogenic estrogen metabolites alter the expression of 17beta-estradiol-regulated proteins including heat shock proteins in human MCF-7 breast cancer cells. | Molecules and cells 20051231 |
Urinary hydroxyestrogens and breast cancer risk among postmenopausal women: a prospective study. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20050901 |
Estrogenic effect of yam ingestion in healthy postmenopausal women. | Journal of the American College of Nutrition 20050801 |
The relationship between physical activity and 2-hydroxyestrone, 16alpha-hydroxyestrone, and the 2/16 ratio in premenopausal women (United States). | Cancer causes & control : CCC 20050501 |
Partition of endocrine-disrupting chemicals between colloids and dissolved phase as determined by cross-flow ultrafiltration. | Environmental science & technology 20050415 |
Degradation of estradiol and ethinyl estradiol by activated sludge and by a defined mixed culture. | Applied microbiology and biotechnology 20050401 |
Differential effects of 16alpha-hydroxyestrone and 2-methoxyestradiol on cyclin D1 involving the transcription factor ATF-2 in MCF-7 breast cancer cells. | Journal of molecular endocrinology 20050201 |
Estradiol metabolites are potent mitogenic substances for human ovarian cancer cells. | European journal of gynaecological oncology 20050101 |
A common CYP1B1 polymorphism is associated with 2-OHE1/16-OHE1 urinary estrone ratio. | Clinical chemistry and laboratory medicine 20050101 |
Urinary estrogen metabolites, prostate specific antigen, and body mass index among African-American men in South Carolina. | Cancer detection and prevention 20050101 |
The oxidative metabolism of estrogen modulates response to ERT/HRT in postmenopausal women. | Bone 20040901 |
Effects of estrogens and metabolites on endometrial carcinogenesis in young adult mice initiated with N-ethyl-N'-nitro-N-nitrosoguanidine. | Cancer letters 20040728 |
Microwave-assisted extraction followed by gas chromatography-mass spectrometry for the determination of endocrine disrupting chemicals in river sediments. | Journal of chromatography. A 20040604 |
Physical activity, body size, and estrogen metabolism in women. | Cancer causes & control : CCC 20040601 |
High levels of oxidative DNA damage in lymphocyte DNA of premenopausal breast cancer patients from Egypt. | International journal of environmental health research 20040401 |
Endogenous estradiol metabolism during treatment with oral contraceptives. | International journal of clinical pharmacology and therapeutics 20040301 |
Synovial fluid estrogens in rheumatoid arthritis. | Autoimmunity reviews 20040301 |
Association of CYP17, CYP19, CYP1B1, and COMT polymorphisms with serum and urinary sex hormone concentrations in postmenopausal women. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20040101 |
Sex hormones influence on the immune system: basic and clinical aspects in autoimmunity. | Lupus 20040101 |
Pilot study: effect of 3,3'-diindolylmethane supplements on urinary hormone metabolites in postmenopausal women with a history of early-stage breast cancer. | Nutrition and cancer 20040101 |
Increased estrogen formation and estrogen to androgen ratio in the synovial fluid of patients with rheumatoid arthritis. | The Journal of rheumatology 20031201 |
Estrogen metabolites and the risk of breast cancer in older women. | Epidemiology (Cambridge, Mass.) 20031101 |
[Estrogen-dependent neoplasia - what is the significance of estradiol metabolites]. | Zentralblatt fur Gynakologie 20031101 |
Human cytochrome P450 3A7 has a distinct high catalytic activity for the 16alpha-hydroxylation of estrone but not 17beta-estradiol. | Cancer research 20031001 |
Activation of matrix metalloproteinase-2 and -9 by 2- and 4-hydroxyestradiol. | The Journal of steroid biochemistry and molecular biology 20031001 |
Urinary equol excretion in relation to 2-hydroxyestrone and 16alpha-hydroxyestrone concentrations: an observational study of young to middle-aged women. | The Journal of steroid biochemistry and molecular biology 20030701 |
Influence of postmenopausal hormone replacement therapy on an estrogen metabolite biomarker of risk for breast cancer. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20030601 |
Predictors of the plasma ratio of 2-hydroxyestrone to 16alpha-hydroxyestrone among pre-menopausal, nulliparous women from four ethnic groups. | Carcinogenesis 20030501 |
Endogenous estradiol metabolites stimulate the in vitro proliferation of human osteoblastic cells. | International journal of clinical pharmacology and therapeutics 20030401 |
A preliminary study of the effect of fluoxetine treatment on the 2:16-alpha-hydroxyestrone ratio in young women. | Therapeutic drug monitoring 20030201 |
Estrogens in female thyroid cancer: alteration of urinary profiles in pre- and post-operative cases. | Cancer letters 20030110 |
Urinary estrogen metabolites and breast cancer: differential pattern of risk found with pre- versus post-treatment collection. | Steroids 20030101 |
Urinary estrogen metabolites and prostate cancer: a case-control study in the United States. | Cancer causes & control : CCC 20021201 |
Tissue content of hydroxyestrogens in relation to survival of breast cancer patients. | Clinical cancer research : an official journal of the American Association for Cancer Research 20021001 |
Estrogen metabolism and the diet-cancer connection: rationale for assessing the ratio of urinary hydroxylated estrogen metabolites. | Alternative medicine review : a journal of clinical therapeutic 20020401 |
Urinary 2-hydroxyestrone/16alpha-hydroxyestrone ratio and family history of breast cancer in premenopausal women. | Breast cancer research and treatment 20020301 |
Regulation of cell cycle and cyclins by 16alpha-hydroxyestrone in MCF-7 breast cancer cells. | Journal of molecular endocrinology 20011201 |
The effects of postmenopausal hormone replacement therapy and oral contraceptives on the endogenous estradiol metabolism. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20011201 |
Relationship between estradiol 16 alpha-hydroxylation and human papillomavirus infection in cervical cell transformation. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20011001 |
Preferential growth stimulation of mammary glands over uterine endometrium in female rats by a naturally occurring estradiol-17beta-fatty acid ester. | Cancer research 20010801 |
Tissue-selective effects of continuous release of 2-hydroxyestrone and 16alpha-hydroxyestrone on bone, uterus and mammary gland in ovariectomized growing rats. | The Journal of endocrinology 20010701 |
Urinary estrogen metabolites and mammographic parenchymal patterns in postmenopausal women. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20010601 |
Re: CYP17 promoter polymorphism and breast cancer in Australian women under age forty years. | Journal of the National Cancer Institute 20010404 |
Determination of estradiol metabolites in human liver microsome by high performance liquid chromatography-electrochemistry detector. | Acta pharmacologica Sinica 20010401 |
Epidemiological study of urinary 6beta-hydroxycortisol to cortisol ratios and breast cancer risk. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20010301 |
Evaluation of an EIA method for measuring serum levels of the estrogen metabolite 2-hydroxyestrone in adults. | Steroids 20010101 |
Oestrogen and progesterone increase the levels of apoptosis induced by the human papillomavirus type 16 E2 and E7 proteins. | The Journal of general virology 20010101 |
Indole-3-carbinol in women with SLE: effect on estrogen metabolism and disease activity. | Lupus 20010101 |
Increased urinary excretion of 2-hydroxyestrone but not 16alpha-hydroxyestrone in premenopausal women during a soya diet containing isoflavones. | Cancer research 20000301 |
Rapid inhibition of rat brain mitochondrial proton F0F1-ATPase activity by estrogens: comparison with Na+, K+ -ATPase of porcine cortex. | European journal of pharmacology 19990226 |
Estrogenic and antiestrogenic activities of 16alpha- and 2-hydroxy metabolites of 17beta-estradiol in MCF-7 and T47D human breast cancer cells. | The Journal of steroid biochemistry and molecular biology 19981201 |
Anti-oestrogen antibodies in users of oral contraceptives and in patients with systemic lupus erythematosus. | Clinical and experimental immunology 19870101 |