Home Sulfos 2-Phenylacetylenesulfonamide

2-Phenylacetylenesulfonamide

CAS No.:
64984-31-2
Catalog Number:
AG00EBLY
Molecular Formula:
C8H7NO2S
Molecular Weight:
181.2117
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
10mg
>98.0%(HPLC)(N)
1 week
United States
$70
- +
100mg
>98.0%(HPLC)(N)
1 week
United States
$212
- +
Product Description
Catalog Number:
AG00EBLY
Chemical Name:
2-Phenylacetylenesulfonamide
CAS Number:
64984-31-2
Molecular Formula:
C8H7NO2S
Molecular Weight:
181.2117
MDL Number:
MFCD00181531
IUPAC Name:
2-phenylethynesulfonamide
InChI:
InChI=1S/C8H7NO2S/c9-12(10,11)7-6-8-4-2-1-3-5-8/h1-5H,(H2,9,10,11)
InChI Key:
ZZUZYEMRHCMVTB-UHFFFAOYSA-N
SMILES:
NS(=O)(=O)C#Cc1ccccc1
NSC Number:
303580
Properties
Complexity:
295  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
181.02g/mol
Formal Charge:
0
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
181.209g/mol
Monoisotopic Mass:
181.02g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
68.5A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.1  
Literature
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Solanesol protects human hepatic L02 cells from ethanol-induced oxidative injury via upregulation of HO-1 and Hsp70. Toxicology in vitro : an international journal published in association with BIBRA 20150401
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Rhodacyanine derivative selectively targets cancer cells and overcomes tamoxifen resistance. PloS one 20120101
Interaction of the ARF tumor suppressor with cytosolic HSP70 contributes to its autophagy function. Cancer biology & therapy 20110915
HSP70 inhibition by the small-molecule 2-phenylethynesulfonamide impairs protein clearance pathways in tumor cells. Molecular cancer research : MCR 20110701
Physical exercise regulates p53 activity targeting SCO2 and increases mitochondrial COX biogenesis in cardiac muscle with age. PloS one 20110101
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Sodium orthovanadate inhibits p53-mediated apoptosis. Cancer research 20100101
A small molecule inhibitor of inducible heat shock protein 70. Molecular cell 20091009
2-Phenylacetylenesulfonamide (PAS) induces p53-independent apoptotic killing of B-chronic lymphocytic leukemia (CLL) cells. Blood 20090806
Small-molecule inhibitor of p53 binding to mitochondria protects mice from gamma radiation. Nature chemical biology 20060901
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. The Journal of biological chemistry 20020419
Properties