2-Phenylacetylenesulfonamide
Title | Journal |
---|---|
HSP70 Inhibition Limits FAK-Dependent Invasion and Enhances the Response to Melanoma Treatment with BRAF Inhibitors. | Cancer research 20160501 |
Cyclosporine A Suppressed Glucose Oxidase Induced P53 Mitochondrial Translocation and Hepatic Cell Apoptosis through Blocking Mitochondrial Permeability Transition. | International journal of biological sciences 20160101 |
Solanesol protects human hepatic L02 cells from ethanol-induced oxidative injury via upregulation of HO-1 and Hsp70. | Toxicology in vitro : an international journal published in association with BIBRA 20150401 |
Pivotal roles of p53 transcription-dependent and -independent pathways in manganese-induced mitochondrial dysfunction and neuronal apoptosis. | Toxicology and applied pharmacology 20141215 |
A comparative study of stress-mediated immunological functions with the adjuvanticity of alum. | The Journal of biological chemistry 20120518 |
Rhodacyanine derivative selectively targets cancer cells and overcomes tamoxifen resistance. | PloS one 20120101 |
Interaction of the ARF tumor suppressor with cytosolic HSP70 contributes to its autophagy function. | Cancer biology & therapy 20110915 |
HSP70 inhibition by the small-molecule 2-phenylethynesulfonamide impairs protein clearance pathways in tumor cells. | Molecular cancer research : MCR 20110701 |
Physical exercise regulates p53 activity targeting SCO2 and increases mitochondrial COX biogenesis in cardiac muscle with age. | PloS one 20110101 |
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
Molecular mechanisms of nutlin-induced apoptosis in multiple myeloma: evidence for p53-transcription-dependent and -independent pathways. | Cancer biology & therapy 20100915 |
BclxL changes conformation upon binding to wild-type but not mutant p53 DNA binding domain. | The Journal of biological chemistry 20100129 |
Sodium orthovanadate inhibits p53-mediated apoptosis. | Cancer research 20100101 |
A small molecule inhibitor of inducible heat shock protein 70. | Molecular cell 20091009 |
2-Phenylacetylenesulfonamide (PAS) induces p53-independent apoptotic killing of B-chronic lymphocytic leukemia (CLL) cells. | Blood 20090806 |
Small-molecule inhibitor of p53 binding to mitochondria protects mice from gamma radiation. | Nature chemical biology 20060901 |
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. | The Journal of biological chemistry 20020419 |