Home Other Building Blocks 1H-Indole, 3-(1,2,3,6-tetrahydro-4-pyridinyl)-

1H-Indole, 3-(1,2,3,6-tetrahydro-4-pyridinyl)-

CAS No.:
65347-55-9
Catalog Number:
AG00EBCK
Molecular Formula:
C13H14N2
Molecular Weight:
198.2637
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
Product Description
Catalog Number:
AG00EBCK
Chemical Name:
1H-Indole, 3-(1,2,3,6-tetrahydro-4-pyridinyl)-
CAS Number:
65347-55-9
Molecular Formula:
C13H14N2
Molecular Weight:
198.2637
MDL Number:
MFCD03695471
IUPAC Name:
3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole
InChI:
InChI=1S/C13H14N2/c1-2-4-13-11(3-1)12(9-15-13)10-5-7-14-8-6-10/h1-5,9,14-15H,6-8H2
InChI Key:
CIRSPTXGPFAXRE-UHFFFAOYSA-N
SMILES:
N1CCC(=CC1)c1c[nH]c2c1cccc2
Properties
Complexity:
259  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
198.116g/mol
Formal Charge:
0
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
198.269g/mol
Monoisotopic Mass:
198.116g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
27.8A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.8  
Literature
Title Journal
Essential role for orbitofrontal serotonin 1B receptors in obsessive-compulsive disorder-like behavior and serotonin reuptake inhibitor response in mice. Biological psychiatry 20111201
Novel 4-aryl-pyrido[1,2-c]pyrimidines with dual SSRI and 5-HT(1A) activity. part 3. European journal of medicinal chemistry 20110101
Chronic reductions in serotonin transporter function prevent 5-HT1B-induced behavioral effects in mice. Biological psychiatry 20090301
Pharmacological alterations of anxious behaviour in mice depending on both strain and the behavioural situation. PloS one 20090101
Anticonvulsant effect of the selective 5-HT1B receptor agonist CP 94253 in mice. European journal of pharmacology 20060710
Postsynaptic 5-HT1B receptors modulate electroshock-induced generalised seizures in rats. British journal of pharmacology 20050301
Stimulation of 5-HT1B receptors decreases cocaine- and sucrose-seeking behavior. Pharmacology, biochemistry, and behavior 20050201
Discriminative stimulus effects of ethanol in rats using a three-choice ethanol-midazolam-water discrimination. Behavioural pharmacology 20041201
Enkephalin contributes to the locomotor stimulating effects of 3,4-methylenedioxy-N-methylamphetamine. The European journal of neuroscience 20030701
SLV310, a novel, potential antipsychotic, combining potent dopamine D2 receptor antagonism with serotonin reuptake inhibition. Bioorganic & medicinal chemistry letters 20030210
Subthalamic 5-HT(1A) and 5-HT(1B) receptor modulation of RU 24969-induced behavioral profile in rats. Pharmacology, biochemistry, and behavior 20020401
Serotonin 2C receptor agonists and the behavioural satiety sequence in mice. Pharmacology, biochemistry, and behavior 20020401
An investigation of the role of 5-HT(2C) receptors in modifying ethanol self-administration behaviour. Pharmacology, biochemistry, and behavior 20020401
Serotonin-1B receptor-mediated inhibition of [(3)H]GABA release from rat ventral tegmental area slices. Journal of neurochemistry 20011101
Role of 5-HT(1A) and 5-HT(1B) receptors in the mediation of behavior in the forced swim test in mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20010401
Properties