Home Other Building Blocks PROSTAGLANDIN J2

PROSTAGLANDIN J2

CAS No.:
60203-57-8
Catalog Number:
AG00EB4E
Molecular Formula:
C20H30O4
Molecular Weight:
334.4498
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1mg
≥95%
1 week
United States
$229
- +
5mg
≥95%
1 week
United States
$779
- +
10mg
≥95%
1 week
United States
$1321
- +
Product Description
Catalog Number:
AG00EB4E
Chemical Name:
PROSTAGLANDIN J2
CAS Number:
60203-57-8
Molecular Formula:
C20H30O4
Molecular Weight:
334.4498
MDL Number:
MFCD00065804
IUPAC Name:
(Z)-7-[(1S,5R)-5-[(E,3S)-3-hydroxyoct-1-enyl]-4-oxocyclopent-2-en-1-yl]hept-5-enoic acid
InChI:
InChI=1S/C20H30O4/c1-2-3-6-10-17(21)13-14-18-16(12-15-19(18)22)9-7-4-5-8-11-20(23)24/h4,7,12-18,21H,2-3,5-6,8-11H2,1H3,(H,23,24)/b7-4-,14-13+/t16-,17-,18+/m0/s1
InChI Key:
UQOQENZZLBSFKO-POPPZSFYSA-N
SMILES:
CCCCCC(/C=C/[C@@H]1C(CC=CCCCC(=O)O)C=CC1=O)O
Properties
Complexity:
476  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
3  
Defined Bond Stereocenter Count:
2  
Exact Mass:
334.214g/mol
Formal Charge:
0
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
334.456g/mol
Monoisotopic Mass:
334.214g/mol
Rotatable Bond Count:
12  
Topological Polar Surface Area:
74.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
3.6  
Literature
Title Journal
Lovastatin lactone elicits human lung cancer cell apoptosis via a COX-2/PPARγ-dependent pathway. Oncotarget 20160301
Prostaglandin D2 toxicity in primary neurons is mediated through its bioactive cyclopentenone metabolites. Neurotoxicology 20131201
Activation of adipogenesis by lipocalin-type prostaglandin D synthase-generated Δ¹²-PGJ₂ acting through PPARγ-dependent and independent pathways. Gene 20120815
Prostaglandin J2 series induces the gene expression of monocyte chemoattractant protein-1 during the maturation phase of cultured adipocytes. Gene 20120710
15-deoxy-Δ12,14 -prostaglandin J2 reduces recruitment of bone marrow-derived monocyte/macrophages in chronic liver injury in mice. Hepatology (Baltimore, Md.) 20120701
Long-term CFTR inhibition modulates 15d-prostaglandin J2 in human pulmonary cells. The international journal of biochemistry & cell biology 20120601
Targeting of histone acetyltransferase p300 by cyclopentenone prostaglandin Δ(12)-PGJ(2) through covalent binding to Cys(1438). Chemical research in toxicology 20120220
Expression of transient receptor potential ankyrin 1 (TRPA1) and its role in insulin release from rat pancreatic beta cells. PloS one 20120101
Systemic PPARγ deletion impairs circadian rhythms of behavior and metabolism. PloS one 20120101
Synergistic induction of lipid catabolism and anti-inflammatory lipids in white fat of dietary obese mice in response to calorie restriction and n-3 fatty acids. Diabetologia 20111001
15-Deoxy-Δ12,14-prostaglandin J2 induces Cox-2 expression in human osteosarcoma cells through MAPK and EGFR activation involving reactive oxygen species. Free radical biology & medicine 20110401
Comparison of UHPLC and HPLC methods for the assay of prostanoids: 'are the methods equivalent in terms of accuracy and precision?'. Bioanalysis 20110401
Activation of peroxisome-proliferator-activated receptors α and γ mediates remote ischemic preconditioning against myocardial infarction in vivo. Experimental biology and medicine (Maywood, N.J.) 20110101
Expression of TREM-1 is inhibited by PGD2 and PGJ2 in macrophages. Experimental cell research 20101115
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. Bioorganic & medicinal chemistry letters 20101101
Transcriptional regulation of CXC-ELR chemokines KC and MIP-2 in mouse pancreatic acini. American journal of physiology. Gastrointestinal and liver physiology 20101001
Involvement of PPARα and PPARγ in apoptosis and proliferation of human hepatocarcinoma HepG2 cells. Cell biochemistry and function 20101001
Evaluation of anti-inflammatory and chondroprotective effects of peroxisome proliferator-activated receptor gamma agonists in cartilage and synovial explants from dogs. American journal of veterinary research 20101001
Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins. Journal of lipid research 20100801
The anti-inflammatory prostaglandin 15-deoxy-delta(12,14)-PGJ2 inhibits CRM1-dependent nuclear protein export. The Journal of biological chemistry 20100716
15-deoxy-Delta12,14 prostaglandin GJ2 but not rosiglitazone regulates metalloproteinase 9, NOS-2, and cyclooxygenase 2 expression and functions by peroxisome proliferator-activated receptor gamma-dependent and -independent mechanisms in cardiac cells. Shock (Augusta, Ga.) 20100701
Mast cell-derived prostaglandin D2 controls hyaluronan synthesis in human orbital fibroblasts via DP1 activation: implications for thyroid eye disease. The Journal of biological chemistry 20100521
PPARgamma regulates LIF-induced growth and self-renewal of mouse ES cells through Tyk2-Stat3 pathway. Cellular signalling 20100301
Aldo-keto reductase 1C3 expression in MCF-7 cells reveals roles in steroid hormone and prostaglandin metabolism that may explain its over-expression in breast cancer. The Journal of steroid biochemistry and molecular biology 20100215
3T3-L1 adipocyte apoptosis induced by thiazolidinediones is peroxisome proliferator-activated receptor-gamma-dependent and mediated by the caspase-3-dependent apoptotic pathway. The FEBS journal 20100201
Chronic immobilisation stress ameliorates clinical score and neuroinflammation in a MOG-induced EAE in Dark Agouti rats: mechanisms implicated. Journal of neuroinflammation 20100101
Purification of reversibly oxidized proteins (PROP) reveals a redox switch controlling p38 MAP kinase activity. PloS one 20100101
Lipid peroxidation: physiological levels and dual biological effects. Free radical biology & medicine 20090901
Peroxisome proliferator-activated receptor gamma agonists enhance lung maturation in a neonatal rat model. Pediatric research 20090201
The resetting of the circadian rhythm by Prostaglandin J2 is distinctly phase-dependent. FEBS letters 20090122
Subchronic infusion of the product of inflammation prostaglandin J2 models sporadic Parkinson's disease in mice. Journal of neuroinflammation 20090101
Sepsis-induced inhibition of neutrophil chemotaxis is mediated by activation of peroxisome proliferator-activated receptor-{gamma}. Blood 20081115
15-deoxy-delta12,14-PGJ2 enhances platelet production from megakaryocytes. Blood 20081115
PGJ2 antagonizes NF-kappaB-induced HIV-1 LTR activation in colonic epithelial cells. Virology 20081010
PPARalpha and PPARgamma effectively protect against HIV-induced inflammatory responses in brain endothelial cells. Journal of neurochemistry 20081001
Mechanism of T cell tolerance induction by murine hepatic Kupffer cells. Hepatology (Baltimore, Md.) 20080901
Intrathecal rosiglitazone acts at peroxisome proliferator-activated receptor-gamma to rapidly inhibit neuropathic pain in rats. The journal of pain : official journal of the American Pain Society 20080701
Activation of peroxisome proliferator-activated receptor-gamma by curcumin blocks the signaling pathways for PDGF and EGF in hepatic stellate cells. Laboratory investigation; a journal of technical methods and pathology 20080501
Statins but not thiazolidinediones attenuate albumin-mediated chemokine production by proximal tubular cells independently of endocytosis. American journal of nephrology 20080101
Inhibition of adhesive interaction between multiple myeloma and bone marrow stromal cells by PPARgamma cross talk with NF-kappaB and C/EBP. Blood 20071215
PPARgamma regulates adipose triglyceride lipase in adipocytes in vitro and in vivo. American journal of physiology. Endocrinology and metabolism 20071201
Modification and activation of Ras proteins by electrophilic prostanoids with different structure are site-selective. Biochemistry 20070605
Effects of peroxisome proliferator-activated receptor gamma agonists on brain glucose and glutamate transporters after stress in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070601
Activation of peroxisome proliferator-activated receptor gamma inhibits cell growth via apoptosis and arrest of the cell cycle in human colorectal cancer. Journal of digestive diseases 20070501
Identification of actin as a 15-deoxy-Delta12,14-prostaglandin J2 target in neuroblastoma cells: mass spectrometric, computational, and functional approaches to investigate the effect on cytoskeletal derangement. Biochemistry 20070313
Downregulation of cyclooxygenase-2 expression and activation of caspase-3 are involved in peroxisome proliferator-activated receptor-gamma agonists induced apoptosis in human monocyte leukemia cells in vitro. Annals of hematology 20070301
Regulation and function of collagenous repeat containing sequence of 26-kDa protein gene product 'cartonectin'. Obesity (Silver Spring, Md.) 20070201
In utero nicotine exposure alters fetal rat lung alveolar type II cell proliferation, differentiation, and metabolism. American journal of physiology. Lung cellular and molecular physiology 20070101
Potential role for peroxisome proliferator-activated receptor gamma in regulating luteal lifespan in the rat. Reproduction (Cambridge, England) 20070101
Peroxisome proliferator-activated receptor (PPAR)gamma is expressed by human spermatozoa: its potential role on the sperm physiology. Journal of cellular physiology 20061201
Prostaglandin-induced programmed cell death in Trypanosoma brucei involves oxidative stress. Cell death and differentiation 20061001
Acetaldehyde inhibits PPARgamma via H2O2-mediated c-Abl activation in human hepatic stellate cells. Gastroenterology 20061001
Cytoskeleton/endoplasmic reticulum collapse induced by prostaglandin J2 parallels centrosomal deposition of ubiquitinated protein aggregates. The Journal of biological chemistry 20060811
Prostaglandin J2 alters pro-survival and pro-death gene expression patterns and 26 S proteasome assembly in human neuroblastoma cells. The Journal of biological chemistry 20060728
Cross metathesis as a general strategy for the synthesis of prostacyclin and prostaglandin analogues. Organic letters 20060706
Peroxisome proliferator-activated receptor-gamma and retinoic acid X receptor alpha represses the TGFbeta1 gene via PTEN-mediated p70 ribosomal S6 kinase-1 inhibition: role for Zf9 dephosphorylation. Molecular pharmacology 20060701
A role of PPAR-gamma in androstenediol-mediated salutary effects on cardiac function following trauma-hemorrhage. Annals of surgery 20060701
Cyclooxygenase-2 mediates the development of cortical spreading depression-induced tolerance to transient focal cerebral ischemia in rats. Neuroscience 20060630
Prostaglandin J2 reduces catechol-O-methyltransferase activity and enhances dopamine toxicity in neuronal cells. Neurobiology of disease 20060501
[Effects of peroxisome proliferators-activated receptor gamma agonists on transforming growth factor-beta1 and Smads signal pathway: experiment with rat renal fibroblasts]. Zhonghua yi xue za zhi 20060321
The thiazolidinedione drug troglitazone up-regulates nitric oxide synthase expression in vascular endothelial cells. Journal of diabetes and its complications 20060101
5-Oxo-ETE analogs and the proliferation of cancer cells. Biochimica et biophysica acta 20051001
Modulation of peroxisome proliferator-activated receptors (PPARs) by PPAR(alpha)- and PPAR(gamma)-specific ligands and by 17beta-estradiol in isolated zebrafish hepatocytes. Toxicology in vitro : an international journal published in association with BIBRA 20050901
Agonists of peroxisome proliferator-activated receptor-gamma attenuate the Abeta-mediated impairment of LTP in the hippocampus in vitro. Neuropharmacology 20050901
Prostaglandin D2 and prostaglandin E2 accelerate the recovery of cutaneous barrier disruption induced by mechanical scratching in mice. European journal of pharmacology 20050725
Inhibitors of the arachidonic acid pathway and peroxisome proliferator-activated receptor ligands have superadditive effects on lung cancer growth inhibition. Cancer research 20050515
Prostaglandin D(2) and J(2) induce apoptosis in human leukemia cells via activation of the caspase 3 cascade and production of reactive oxygen species. Biochimica et biophysica acta 20050415
The possible role of heat shock factor-1 in the negative regulation of heme oxygenase-1. The international journal of biochemistry & cell biology 20050301
Effects of PPAR-gamma ligands on vascular smooth muscle marker expression in hypertensive and normal arteries. American journal of physiology. Heart and circulatory physiology 20050101
The CNS pericyte response to low oxygen: early synthesis of cyclopentenone prostaglandins of the J-series. Microvascular research 20050101
Unusual astrocyte reactivity caused by the food mycotoxin ochratoxin A in aggregating rat brain cell cultures. Neuroscience 20050101
Neurotoxic prostaglandin J2 enhances cyclooxygenase-2 expression in neuronal cells through the p38MAPK pathway: a death wish? Journal of neuroscience research 20041215
[Cytokines, prostaglandins, nutritive and non-nuitritive factors in inflammatory bowel diseases]. Orvosi hetilap 20041212
Prostanoid DP1 receptor agonist inhibits the pruritic activity in NC/Nga mice with atopic dermatitis. European journal of pharmacology 20041128
Peroxisome proliferator-activated receptor and farnesoid X receptor ligands differentially regulate sebaceous differentiation in human sebaceous gland organ cultures in vitro. The British journal of dermatology 20041001
15d-prostaglandin J2 reduces multiple organ failure caused by wall-fragment of Gram-positive and Gram-negative bacteria. European journal of pharmacology 20040913
15-deoxy-delta12,14-prostaglandin J2-mediated ERK signaling inhibits gram-negative bacteria-induced RelA phosphorylation and interleukin-6 gene expression in intestinal epithelial cells through modulation of protein phosphatase 2A activity. The Journal of biological chemistry 20040820
Lysophosphatidic acid attenuates the cytotoxic effects and degree of peroxisome proliferator-activated receptor gamma activation induced by 15-deoxyDelta12,14-prostaglandin J2 in neuroblastoma cells. The Biochemical journal 20040815
The PPARgamma ligands PGJ2 and rosiglitazone show a differential ability to inhibit proliferation and to induce apoptosis and differentiation of human glioblastoma cell lines. International journal of oncology 20040801
Delta12-Prostaglandin J2 inhibits the ubiquitin hydrolase UCH-L1 and elicits ubiquitin-protein aggregation without proteasome inhibition. Biochemical and biophysical research communications 20040709
Transactivation of the PPAR-responsive enhancer module in chemopreventive glutathione S-transferase gene by the peroxisome proliferator-activated receptor-gamma and retinoid X receptor heterodimer. Cancer research 20040515
Rapid change of glucose concentration promotes mesangial cell proliferation via VEGF: inhibitory effects of thiazolidinedione. Biochemical and biophysical research communications 20040423
Rosiglitazone prevents the impairment of human islet function induced by fatty acids: evidence for a role of PPARgamma2 in the modulation of insulin secretion. American journal of physiology. Endocrinology and metabolism 20040401
The biphasic effects of cyclopentenone prostaglandins, prostaglandin J(2) and 15-deoxy-Delta(12,14)-prostaglandin J(2) on proliferation and apoptosis in rat basophilic leukemia (RBL-2H3) cells. Biochemical pharmacology 20040401
Prostaglandins are powerful inducers of NGF and BDNF production in mouse astrocyte cultures. FEBS letters 20040326
PPARgamma is not required for the inhibitory actions of PGJ2 on cytokine signaling in pancreatic beta-cells. American journal of physiology. Endocrinology and metabolism 20040301
A new class of peroxisome proliferator-activated receptor gamma (PPARgamma) agonists that inhibit growth of breast cancer cells: 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes. Molecular cancer therapeutics 20040301
Expression of NAG-1, a transforming growth factor-beta superfamily member, by troglitazone requires the early growth response gene EGR-1. The Journal of biological chemistry 20040220
Antitumor effects of peroxisome proliferator activate receptor gamma ligands on anaplastic thyroid carcinoma. International journal of oncology 20040101
The cellular response to PPARgamma ligands is related to the phenotype of neuroblastoma cell lines. Oncology research 20040101
2-Cyclopenten-1-one and prostaglandin J2 reduce restenosis after balloon angioplasty in rats: role of NF-kappaB. FEBS letters 20031009
The effect of PPARgamma ligands on the proliferation and apoptosis of human melanoma cells. Melanoma research 20031001
A --> J prostaglandin swap: a new tactic for cyclopentenone prostaglandin synthesis. The Journal of organic chemistry 20030822
Peroxisome proliferator-activated receptor-gamma represses GLUT4 promoter activity in primary adipocytes, and rosiglitazone alleviates this effect. The Journal of biological chemistry 20030815
TNF-alpha induction of lipolysis is mediated through activation of the extracellular signal related kinase pathway in 3T3-L1 adipocytes. Journal of cellular biochemistry 20030815
First enantioselective total synthesis of (8S,12R,15S)-prostaglandin J(2). The Journal of organic chemistry 20030808
Inverse relationship between the expression of messenger ribonucleic acid for peroxisome proliferator-activated receptor gamma and P450 side chain cleavage in the rat ovary. Biology of reproduction 20030801
Expression and molecular pharmacology of the mouse CRTH2 receptor. The Journal of pharmacology and experimental therapeutics 20030801
First total synthesis of JS isoprostane. The Journal of organic chemistry 20030725
Activation of peroxisome proliferator-activated receptor-gamma inhibits differentiation of preosteoblasts. The Journal of laboratory and clinical medicine 20030701
Role of heme oxygenase-1 protein in the neuroprotective effects of cyclopentenone prostaglandin derivatives under oxidative stress. The European journal of neuroscience 20030601
Regulation of heme oxygenase expression by cyclopentenone prostaglandins. Experimental biology and medicine (Maywood, N.J.) 20030501
Prostaglandins of J series control heme oxygenase expression: potential significance in modulating neuroinflammation. Annals of the New York Academy of Sciences 20030501
15d-PGJ2 and rosiglitazone suppress Janus kinase-STAT inflammatory signaling through induction of suppressor of cytokine signaling 1 (SOCS1) and SOCS3 in glia. The Journal of biological chemistry 20030425
PPAR agonists protect mesangial cells from interleukin 1beta-induced intracellular lipid accumulation by activating the ABCA1 cholesterol efflux pathway. Journal of the American Society of Nephrology : JASN 20030301
Peroxisome proliferator-activated receptor gamma agonists induce proteasome-dependent degradation of cyclin D1 and estrogen receptor alpha in MCF-7 breast cancer cells. Cancer research 20030301
Activation of PPARgamma increases PTEN expression in pancreatic cancer cells. Biochemical and biophysical research communications 20030131
The aldo-keto reductase AKR1C3 is a novel suppressor of cell differentiation that provides a plausible target for the non-cyclooxygenase-dependent antineoplastic actions of nonsteroidal anti-inflammatory drugs. Cancer research 20030115
Stimulation of proximal tubular cell apoptosis by albumin-bound fatty acids mediated by peroxisome proliferator activated receptor-gamma. Journal of the American Society of Nephrology : JASN 20030101
Activation of peroxisome proliferator-activated receptor alpha in human endothelial cells increases plasminogen activator inhibitor type-1 expression. Chinese medical journal 20030101
Hyperoxia augments pulmonary lipofibroblast-to-myofibroblast transdifferentiation. Cell biochemistry and biophysics 20030101
Prostaglandin-J(2) upregulates expression of matrix metalloproteinase-1 independently of activation of peroxisome proliferator-activated receptor-gamma. Acta biochimica Polonica 20030101
Molecular pharmacology of the human prostaglandin D2 receptor, CRTH2. British journal of pharmacology 20021201
[Cyclopentenone prostaglandin derivatives as neuroprotective compounds]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20021201
Thrombomodulin expression by THP-1 but not by vascular endothelial cells is upregulated by pioglitazone. Thrombosis research 20021125
Peroxisome proliferators compete and ameliorate Hcy-mediated endocardial endothelial cell activation. American journal of physiology. Cell physiology 20021001
PPARgamma and vascular inflammation: adding another piece to the puzzle. Circulation research 20020906
Vascular inflammation is negatively autoregulated by interaction between CCAAT/enhancer-binding protein-delta and peroxisome proliferator-activated receptor-gamma. Circulation research 20020906
Human colorectal cancer cells efficiently conjugate the cyclopentenone prostaglandin, prostaglandin J(2), to glutathione. Biochimica et biophysica acta 20020905
Stimulation of peroxisome proliferator-activated receptors alpha and gamma blocks HIV-1 replication and TNFalpha production in acutely infected primary blood cells, chronically infected U1 cells, and alveolar macrophages from HIV-infected subjects. Journal of acquired immune deficiency syndromes (1999) 20020901
Thiazolidinedione activation of peroxisome proliferator-activated receptor gamma can enhance mitochondrial potential and promote cell survival. The Journal of biological chemistry 20020830
Effect of prostaglandin-J(2) on VEGF synthesis depends on the induction of heme oxygenase-1. Antioxidants & redox signaling 20020801
Inhibitory properties of antitumor prostaglandins against topoisomerases. Bioscience, biotechnology, and biochemistry 20020801
Sox-4 is a positive regulator of Hep3B and HepG2 cells' apoptosis induced by prostaglandin (PG)A(2) and delta(12)-PGJ(2). Experimental & molecular medicine 20020731
Regulation of the interleukin-1 receptor antagonist in THP-1 cells by ligands of the peroxisome proliferator-activated receptor gamma. Cytokine 20020621
Prostaglandin D2 and its metabolites induce caspase-dependent granulocyte apoptosis that is mediated via inhibition of I kappa B alpha degradation using a peroxisome proliferator-activated receptor-gamma-independent mechanism. Journal of immunology (Baltimore, Md. : 1950) 20020615
Induction of apoptosis in human and rat glioma by agonists of the nuclear receptor PPARgamma. Journal of neurochemistry 20020601
The increase in plasminogen activator inhibitor type-1 expression by stimulation of activators for peroxisome proliferator-activated receptors in human endothelial cells. Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih 20020601
Mechanism of constrictive vascular remodeling by homocysteine: role of PPAR. American journal of physiology. Cell physiology 20020501
Inhibition of human chondrosarcoma cell growth via apoptosis by peroxisome proliferator-activated receptor-gamma. British journal of cancer 20020422
Troglitazone, an insulin-sensitizing thiazolidinedione, represses combined stimulation by LH and insulin of de novo androgen biosynthesis by thecal cells in vitro. The Journal of clinical endocrinology and metabolism 20020301
Synergistic effect of 4-hydroxynonenal and PPAR ligands in controlling human leukemic cell growth and differentiation. Free radical biology & medicine 20020201
Peroxisome proliferator-activated receptor gamma activators inhibit MMP-1 production in human synovial fibroblasts likely by reducing the binding of the activator protein 1. Osteoarthritis and cartilage 20020201
PPAR-gamma ligands modulate effects of LPS in stimulated rat synovial fibroblasts. American journal of physiology. Cell physiology 20020101
Role of cyclopentenone prostaglandins in rat carrageenin pleurisy. FEBS letters 20011109
Lipid peroxidation end products-responded induction of a preneoplastic marker enzyme glutathione S-transferase P-form (GST-P) in rat liver on admistration via the portal vein. Mutation research 20011101
Prostaglandin-J2 induces synthesis of interleukin-8 by endothelial cells in a PPAR-gamma-independent manner. Prostaglandins & other lipid mediators 20011001
Cyclopentenone prostaglandins inhibit cytokine-induced nf-kappab activation and chemokine production by human mesangial cells. Journal of the American Society of Nephrology : JASN 20010801
Comparative actions of insulin sensitizers on ion channels in vascular smooth muscle. European journal of pharmacology 20010629
Cloning of the human cholesteryl ester hydrolase promoter: identification of functional peroxisomal proliferator-activated receptor responsive elements. Biochemical and biophysical research communications 20010622
Involvement of p21(WAF1/Cip1), p27(Kip1), and p18(INK4c) in troglitazone-induced cell-cycle arrest in human hepatoma cell lines. Hepatology (Baltimore, Md.) 20010501
Dual function of troglitazone in ICAM-1 gene expression in human vascular endothelium. Biochemical and biophysical research communications 20010406
Prostaglandin J(2) inhibition of mesangial cell iNOS expression. Clinical immunology (Orlando, Fla.) 20010301
PPAR gamma: an essential role in metabolic control. Nutrition, metabolism, and cardiovascular diseases : NMCD 20010201
15-Deoxy-Delta(12,14)-prostaglandin J(2) facilitates thyroglobulin production by cultured human thyrocytes. American journal of physiology. Cell physiology 20001201
Localization of a cyclopentenone prostaglandin to the endoplasmic reticulum and induction of BiP mRNA. The Biochemical journal 19981001
Characterization of the recombinant human prostanoid DP receptor and identification of L-644,698, a novel selective DP agonist. British journal of pharmacology 19980401
Prostaglandins stimulate the stress-induced synthesis of hsp27 and alpha B crystallin. Journal of cellular physiology 19970301
Stereoselective conjugation of prostaglandin A2 and prostaglandin J2 with glutathione, catalyzed by the human glutathione S-transferases A1-1, A2-2, M1a-1a, and P1-1. Chemical research in toxicology 19970301
Inhibition of nuclear factor kappa B by prostaglandin A1: an effect associated with heat shock transcription factor activation. Proceedings of the National Academy of Sciences of the United States of America 19970121
Inhibition of HIV-1 replication by cyclopentenone prostaglandins in acutely infected human cells. Evidence for a transcriptional block. The Journal of clinical investigation 19960415
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