N-Desmethylclozapine
| Title | Journal |
|---|---|
| The Value of Desmethylclozapine and Serum CRP in Clozapine Toxicity: A Case Report. | Case reports in psychiatry 20120101 |
| Effect of food on the pharmacokinetics of clozapine orally disintegrating tablet 12.5 mg: a randomized, open-label, crossover study in healthy male subjects. | Clinical drug investigation 20090101 |
| Interindividual variation in relative CYP1A2/3A4 phenotype influences susceptibility of clozapine oxidation to cytochrome P450-specific inhibition in human hepatic microsomes. | Drug metabolism and disposition: the biological fate of chemicals 20081201 |
| Massively parallel screening of the receptorome. | Combinatorial chemistry & high throughput screening 20080701 |
| Bioequivalence of clozapine orally disintegrating 100-mg tablets compared with clozapine solid oral 100-mg tablets after multiple doses in patients with schizophrenia. | Clinical drug investigation 20080101 |
| Structural requirements of transmembrane domain 3 for activation by the M1 muscarinic receptor agonists AC-42, AC-260584, clozapine, and N-desmethylclozapine: evidence for three distinct modes of receptor activation. | Molecular pharmacology 20061201 |
| High throughput therapeutic drug monitoring of clozapine and metabolites in serum by on-line coupling of solid phase extraction with liquid chromatography-mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060413 |
| Drug-induced activation of SREBP-controlled lipogenic gene expression in CNS-related cell lines: marked differences between various antipsychotic drugs. | BMC neuroscience 20060101 |
| Increased serum S100B in elderly, chronic schizophrenic patients: negative correlation with deficit symptoms. | Schizophrenia research 20051215 |
| Increased serum interleukin-1beta and interleukin-6 in elderly, chronic schizophrenic patients on stable antipsychotic medication. | Neuropsychiatric disease and treatment 20050601 |
| An inter-ethnic comparison study of clozapine dosage, clinical response and plasma levels. | International clinical psychopharmacology 20050501 |
| Dopamine uptake inhibitor-induced rotation in 6-hydroxydopamine-lesioned rats involves both D1 and D2 receptors but is modulated through 5-hydroxytryptamine and noradrenaline receptors. | The Journal of pharmacology and experimental therapeutics 20050301 |
| Field-amplified sample stacking in capillary electrophoresis for the determination of clozapine, clozapine N-oxide, and desmethylclozapine in schizophrenics' plasma. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040925 |
| Effects of clozapine and its metabolites on the 5-HT2 receptor system in cortical and hippocampal cells in vitro. | Progress in neuro-psychopharmacology & biological psychiatry 20040301 |
| Differing response to antipsychotic therapy in schizophrenia: pharmacogenomic aspects. | Dialogues in clinical neuroscience 20040301 |
| N-desmethylclozapine, an allosteric agonist at muscarinic 1 receptor, potentiates N-methyl-D-aspartate receptor activity. | Proceedings of the National Academy of Sciences of the United States of America 20031111 |
| Pharmacokinetics of clozapine and its metabolites in hippocampal HT22 cells. | European journal of pharmacology 20030829 |
| Induction of hyperglycemia in mice with atypical antipsychotic drugs that inhibit glucose uptake. | Pharmacology, biochemistry, and behavior 20030501 |
| Central effects of clozapine in regulating micturition in anesthetized rats. | BMC pharmacology 20020101 |
| Correlation of antipsychotic and prolactin concentrations in children and adolescents acutely treated with haloperidol, clozapine, or olanzapine. | Journal of child and adolescent psychopharmacology 20020101 |
| Inhibition of glucose transport in PC12 cells by the atypical antipsychotic drugs risperidone and clozapine, and structural analogs of clozapine. | Brain research 20011227 |
| Tertiary N-glucuronides of clozapine and its metabolite desmethylclozapine in patient urine. | Drug metabolism and disposition: the biological fate of chemicals 20011001 |
| Isolation and identification of clozapine metabolites in patient urine. | Drug metabolism and disposition: the biological fate of chemicals 20010601 |
| Rapid capillary electrophoretic method for the determination of clozapine and desmethylclozapine in human plasma. | Journal of chromatography. A 20010504 |
| Lack of CYP3A4 inhibition by grapefruit juice and ketoconazole upon clozapine administration in vivo. | Drug metabolism and drug interactions 20010101 |
| Ciprofloxacin increases serum clozapine and N-desmethylclozapine: a study in patients with schizophrenia. | European journal of clinical pharmacology 20001101 |
| Metabolites of the antipsychotic agent clozapine inhibit the replication of human immunodeficiency virus type 1. | Schizophrenia research 19970503 |
| Plasma clozapine levels and the treatment of L-DOPA-induced psychosis in Parkinson's disease. A high potency effect of clozapine. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 19950201 |