[ Bone and cartilage destruction in RA and its intervention. Disease-modifying antirheumatic drugs].

Clinical calcium 20120201

Risk of orthopedic surgical site infections in patients with rheumatoid arthritis treated with antitumor necrosis factor alfa therapy.

International journal of rheumatology 20120101

The observation of humoral responses after influenza vaccination in patients with rheumatoid arthritis treated with Japanese oriental (kampo) medicine: an observational study.

Evidence-based complementary and alternative medicine : eCAM 20120101

Studies of the efficacy and safety of methotrexate at dosages over 8 mg/week using the IORRA cohort database.

Modern rheumatology 20111201

Proximal tubules and podocytes are toxicity targets of bucillamine in a mouse model of drug-induced kidney injury.

European journal of pharmacology 20111116

Free-radical degradation of high-molecular-weight hyaluronan induced by ascorbate plus cupric ions. Testing of bucillamine and its SA981-metabolite as antioxidants.

Journal of pharmaceutical and biomedical analysis 20111101

[Treatment of rheumatic diseases: current status and future prospective. Topics: II. Immunosuppressant/antirheumatic drugs; 6. Bucillamine and gold (gold sodium thiomalate and auranofin)].

Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20111010

Efficacy and safety of additional use of tacrolimus in patients with early rheumatoid arthritis with inadequate response to DMARDs--a multicenter, double-blind, parallel-group trial.

Modern rheumatology 20111001

Postmarketing surveillance of safety and effectiveness of etanercept in Japanese patients with rheumatoid arthritis.

Modern rheumatology 20110801

A multicentre trial of bucillamine in the treatment of early rheumatoid arthritis (SNOW study).

Modern rheumatology 20110601

Aberrant splicing of the hRasGRP4 transcript and decreased levels of this signaling protein in the peripheral blood mononuclear cells in a subset of patients with rheumatoid arthritis.

Arthritis research & therapy 20110101

Chemerin activates fibroblast-like synoviocytes in patients with rheumatoid arthritis.

Arthritis research & therapy 20110101

Organizing pneumonia in a patient with rheumatoid arthritis treated with etanercept.

Modern rheumatology 20101201

Attenuation of warm ischemia-reperfusion injury in the liver by bucillamine through decreased neutrophil activation and Bax/Bcl-2 modulation.

Journal of gastroenterology and hepatology 20101201

Combined effects of bucillamine and etanercept on a rat type II collagen-induced arthritis model.

Modern rheumatology 20100801

N-(tert)-butyloxycarbonyl)-beta,beta-cyclopentyl-cysteine (acetamidomethyl)-methyl ester for synthesis of novel peptidomimetic derivatives.

Protein and peptide letters 20100701

Clinical efficacy of tocilizumab in patients with active rheumatoid arthritis in real clinical practice.

Rheumatology international 20100601

Multiple vertebral involvement of rheumatoid arthritis in thoracolumbar spine: a case report.

Journal of Korean medical science 20100301

Description of the efficacy and safety of three new biologics in the treatment of rheumatoid arthritis.

The Korean journal of internal medicine 20100301

Chlorobenzene induces oxidative stress in human lung epithelial cells in vitro.

Toxicology and applied pharmacology 20100101

A comprehensive molecular interaction map for rheumatoid arthritis.

PloS one 20100101

MicroRNA-146a expresses in interleukin-17 producing T cells in rheumatoid arthritis patients.

BMC musculoskeletal disorders 20100101

A case of rheumatoid arthritis with bucillamine-induced yellow nail syndrome initially manifesting as pulmonary disease.

Clinical medicine insights. Case reports 20100101

The investigation of synovial genomic targets of bucillamine with microarray technique.

Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20090901

Japan College of Rheumatology 2009 guidelines for the use of tocilizumab, a humanized anti-interleukin-6 receptor monoclonal antibody, in rheumatoid arthritis.

Modern rheumatology 20090801

Development and validation of a reversed-phase fluorescence HPLC method for determination of bucillamine in human plasma using pre-column derivatization with monobromobimane.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090715

Multinational evidence-based recommendations for the use of methotrexate in rheumatic disorders with a focus on rheumatoid arthritis: integrating systematic literature research and expert opinion of a broad international panel of rheumatologists in the 3E Initiative.

Annals of the rheumatic diseases 20090701

Efficacy and toxicity of methotrexate (MTX) monotherapy versus MTX combination therapy with non-biological disease-modifying antirheumatic drugs in rheumatoid arthritis: a systematic review and meta-analysis.

Annals of the rheumatic diseases 20090701

Long-term safety of methotrexate monotherapy in patients with rheumatoid arthritis: a systematic literature research.

Annals of the rheumatic diseases 20090701

Efficacy of mizoribine pulse therapy in patients with rheumatoid arthritis who show a reduced or insufficient response to infliximab.

Modern rheumatology 20090601

Laboratory and febrile features after joint surgery in patients with rheumatoid arthritis treated with tocilizumab.

Annals of the rheumatic diseases 20090501

Bucillamine improves hepatic microcirculation and reduces hepatocellular injury after liver warm ischaemia-reperfusion injury.

HPB : the official journal of the International Hepato Pancreato Biliary Association 20090501

[Effect of disease modifying anti-rheumatic drugs on radiographic progression in rheumatoid arthritis].

Clinical calcium 20090301

[Two cases with ankylosing spondylitis using infliximab (case report)].

Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology 20090201

Etanercept improved primary biliary cirrhosis associated with rheumatoid arthritis.

Joint, bone, spine : revue du rhumatisme 20090101

Differential influences of bucillamine and methotrexate on the generation of fibroblast-like cells from bone marrow CD34+ cells of rheumatoid arthritis patients.

International immunopharmacology 20090101

A comparative study of the effects of bucillamine and salazosulfapyridine in the treatment of rheumatoid arthritis.

Modern rheumatology 20090101

Co-existence of acute myeloid leukemia with multilineage dysplasia and Epstein-Barr virus-associated T-cell lymphoproliferative disorder in a patient with rheumatoid arthritis: a case report.

Journal of hematology & oncology 20090101

Radiographic repair in three Japanese patients with rheumatoid arthritis treated with bucillamine.

Modern rheumatology 20090101

Nuclear phosphatidylcholine and sphingomyelin metabolism of thyroid cells changes during stratospheric balloon flight.

Journal of biomedicine & biotechnology 20090101

[Antirheumatic agents for treatment of rheumatoid arthritis].

Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20081010

Prolonged administration of a dithiol antioxidant protects against ventricular remodeling due to ischemia-reperfusion in mice.

American journal of physiology. Heart and circulatory physiology 20080901

[False-positive reaction of urinary ketone bodies caused by bucillamine].

Rinsho byori. The Japanese journal of clinical pathology 20080701

Clinical investigation in highly disease-affected rheumatoid arthritis patients in Japan with adalimumab applying standard and general evaluation: the CHANGE study.

Modern rheumatology 20080601

[A patient with Mycobacterium avium lung disease presenting with rapid, progressive and multiple cavity formation, who had been treated rheumatoid arthritis with disease modifying anti-rheumatic drugs (DMARDs)].

Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20080301

Photoprotective effects of bucillamine against UV-induced damage in an SKH-1 hairless mouse model.

Photochemistry and photobiology 20080101

Eosinophilic pneumonia (EP) associated with rheumatoid arthritis in which drug-induced eosinophilic pneumonia could be ruled out.

Internal medicine (Tokyo, Japan) 20080101

A case with life-threatening interstitial pneumonia associated with bucillamine treatment.

Modern rheumatology 20080101

The efficacy and safety of bucillamine as a second-line DMARD in the treatment of rheumatoid arthritis: a retrospective cohort study.

Modern rheumatology 20080101

Bucillamine mechanism inhibiting IL-1beta-induced VEGF production from fibroblast-like synoviocytes.

International immunopharmacology 20071205

Spontaneous multiple insufficiency fractures after pelvic abscess and sepsis in a rheumatoid arthritis patient treated with high-load corticosteroid therapy: a case report.

Clinical rheumatology 20071101

[Adverse effects of conventional DMARDs and biologic DMARDs].

Nihon rinsho. Japanese journal of clinical medicine 20071028

[Drug-induced nephrotic syndrome].

Nihon rinsho. Japanese journal of clinical medicine 20071028

[Effective combination therapy of TNF antagonists with DMARDs].

Nihon rinsho. Japanese journal of clinical medicine 20070701

Acute exacerbation of preexisting interstitial lung disease after administration of etanercept for rheumatoid arthritis.

The Journal of rheumatology 20070501

Yellow nails under bucillamine therapy for rheumatoid arthritis: a report of two cases.

Rheumatology international 20070401

Scientific basis for the efficacy of combined use of antirheumatic drugs against bone destruction in rheumatoid arthritis.

Modern rheumatology 20070101

Ten years results of bucillamine in the treatment of rheumatoid arthritis.

Modern rheumatology 20070101

Pemphigus foliaceus induced by bucillamine.

European journal of dermatology : EJD 20070101

No correlation exists between disease activity and the expression of killer-cell immunoglobulin-like receptors in patients with rheumatoid arthritis.

Mediators of inflammation 20070101

NF-kappaB inhibitor dehydroxymethylepoxyquinomicin suppresses osteoclastogenesis and expression of NFATc1 in mouse arthritis without affecting expression of RANKL, osteoprotegerin or macrophage colony-stimulating factor.

Arthritis research & therapy 20070101

A case of bucillamine-induced interstitial pneumonia with positive lymphocyte stimulation test for bucillamine using bronchoalveolar lavage lymphocytes.

Internal medicine (Tokyo, Japan) 20070101

Hemophagocytic syndrome associated with rheumatoid arthritis.

Internal medicine (Tokyo, Japan) 20070101

[Therapeutic management of systemic sclerosis].

Presse medicale (Paris, France : 1983) 20061201

Antioxidant properties of bucillamine: possible mode of action.

Biochemical and biophysical research communications 20061027

Bucillamine induces glutathione biosynthesis via activation of the transcription factor Nrf2.

Biochemical pharmacology 20060814

Radiographic appearance of bronchiolitis obliterans organizing pneumonia (BOOP) developing during Bucillamine treatment for rheumatoid arthritis.

The American journal of the medical sciences 20060701

Bucillamine-induced pemphigus vulgaris in a patient with rheumatoid arthritis and polymyositis overlap syndrome.

Journal of Korean medical science 20060601

Guidelines for the proper use of etanercept in Japan.

Modern rheumatology 20060401

Anti-oxidant and pro-oxidant behaviour of bucillamine.

Luminescence : the journal of biological and chemical luminescence 20060101

A case of interstitial pneumonia caused by bucillamine: a study using serological markers.

Modern rheumatology 20060101

Efficacy and safety of bucillamine, a D-penicillamine analogue, in patients with active rheumatoid arthritis.

Modern rheumatology 20060101

Outcome and treatment of bucillamine-induced nephropathy.

Nephron. Clinical practice 20060101

Treatment continuation rate in relation to efficacy and toxicity in long-term therapy with low-dose methotrexate, sulfasalazine, and bucillamine in 1,358 Japanese patients with rheumatoid arthritis.

Clinical and experimental rheumatology 20060101

Inhibitory effect of bucillamine on the increased leukocyte entrapment in the retinal microcirculation of diabetic rats.

Japanese journal of ophthalmology 20060101

The role of thiols in liver ischemia-reperfusion injury.

Current pharmaceutical design 20060101

Efficacy profile of bucillamine in rheumatoid arthritis patients in a large observational cohort study, IORRA.

Modern rheumatology 20060101

The inhibitory effect of disease-modifying anti-rheumatic drugs and steroids on gliostatin/platelet-derived endothelial cell growth factor production in human fibroblast-like synoviocytes.

Rheumatology international 20051001

Rheumatoid factor is a marker of disease severity in Korean rheumatoid arthritis.

Yonsei medical journal 20050831

Quantitative analysis of bucillamine and its pharmaceutical formulation using FT-IR spectroscopy.

Farmaco (Societa chimica italiana : 1989) 20050801

Bucillamine-induced toxic epidermal necrolysis and fixed drug eruption.

The Journal of dermatology 20050501

[Examination of the escape phenomenon in disease modifying antirheumatic drugs].

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20050301

Clinical analysis of 21 patients with psoriasis arthropathy.

The Journal of dermatology 20050201

[Bucillamine-induced dermatomyositis-like clinical features in a patient with rheumatoid arthritis].

Rinsho shinkeigaku = Clinical neurology 20050101

The ability of disease modifying antirheumatic drugs to induce and maintain improvement in patients with rheumatoid arthritis. epidemiology of DMARDs treatment in Japan.

Clinical and experimental rheumatology 20050101

[Disease modifying anti-rheumatic drugs (DMARDs): an overview].

Nihon rinsho. Japanese journal of clinical medicine 20050101

The role of the T cell in autoimmune inflammation.

Arthritis research & therapy 20050101

Therapeutic effects of the combination of methotrexate and bucillamine in early rheumatoid arthritis: a multicenter, double-blind, randomized controlled study.

Modern rheumatology 20050101

Asymptomatic interstitial pneumonitis induced by bucillamine in a patient with rheumatoid arthritis.

Modern rheumatology 20050101

Quantitative analysis of bucillamine in blood using high-performance liquid chromatography-mass spectrometry technique.

Biomedical chromatography : BMC 20041201

[Drug induced nephrotic syndrome].

Nihon rinsho. Japanese journal of clinical medicine 20041001

Patients with rheumatoid arthritis (RA) and proteinuria.

Clinical and experimental nephrology 20040901

Bucillamine induces the synthesis of vascular endothelial growth factor dose-dependently in systemic sclerosis fibroblasts via nuclear factor-kappaB and simian virus 40 promoter factor 1 pathways.

Molecular pharmacology 20040201

Adult-onset Still's disease with disseminated intravascular coagulation and multiple organ dysfunctions dramatically treated with cyclosporine A.

Journal of Korean medical science 20040201

Inhibitory effects of bucillamine on the expression of vascular cell adhesion molecule-1 in human umbilical vein endothelial cells.

International immunopharmacology 20040101

Triptolide, an active compound identified in a traditional Chinese herb, induces apoptosis of rheumatoid synovial fibroblasts.

BMC pharmacology 20040101

Treatment of retinopathy of prematurity with topical ketorolac tromethamine: a preliminary study.

BMC pediatrics 20040101

Clinical course of bucillamine-induced nephropathy in patients with rheumatoid arthritis.

Clinical and experimental nephrology 20031201

Simultaneous, clonally identical T cell expansion in tonsil and synovium in a patient with rheumatoid arthritis and chronic tonsillitis.

Arthritis and rheumatism 20030901

[Pharmacokinetics of salazosulfapyridine in a hemodialysis patient].

Ryumachi. [Rheumatism] 20030601

[A case of sarcoidosis overlapping with rheumatoid arthritis].

Nihon Jinzo Gakkai shi 20030101

Bucillamine: a potent thiol donor with multiple clinical applications.

Cardiovascular drug reviews 20030101

Subconjunctival administration of bucillamine suppresses choroidal neovascularization in rat.

Investigative ophthalmology & visual science 20021101

Inhibitory mechanism of vascular endothelial growth factor (VEGF) by bucillamine.

British journal of pharmacology 20021101

Gigantomastia induced by bucillamine.

Annals of plastic surgery 20020801

Inhibitory effects of bucillamine on increased blood-retinal barrier permeability in streptozotocin-induced diabetic rats.

Current eye research 20020701

Bucillamine induces membranous glomerulonephritis.

American journal of kidney diseases : the official journal of the National Kidney Foundation 20020401

[A case of pulmonary infiltration with eosinophilia (PIE) syndrome induced by bucillamine treatment of rheumatoid arthritis].

Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20020401

Thiol antioxidants inhibit the adjuvant effects of aerosolized diesel exhaust particles in a murine model for ovalbumin sensitization.

Journal of immunology (Baltimore, Md. : 1950) 20020301

[A case of rheumatoid arthritis complicated with a pneumonitis during concomitant treatment with methotrexate and bucillamine].

Ryumachi. [Rheumatism] 20020201

Angiogenesis in rheumatoid arthritis.

Arthritis research 20020101

VEGF and imaging of vessels in rheumatoid arthritis.

Arthritis research 20020101

Inhibitory effect of bucillamine on laser-induced choroidal neovascularization in rats.

Current eye research 20020101

Two injections of interferon-alpha could trigger the development of rheumatoid arthritis.

Clinical and experimental rheumatology 20020101

Oxygen-sensing mechanisms and the regulation of redox-responsive transcription factors in development and pathophysiology.

Respiratory research 20020101

KE-758, an active metabolite of the new anti-rheumatic drug KE-298, suppresses production of tumor necrosis factor-alpha and interleukin-1 beta in THP-1, a human monocyte cell line.

Drugs under experimental and clinical research 20020101

Bucillamine prevents myocardial reperfusion injury.

Journal of cardiovascular pharmacology 20011201

Methotrexate inhibits rheumatoid synovitis by inducing apoptosis.

The Journal of rheumatology 20010801

Effects of KE-758; an active metabolite of the new anti-rheumatic drug KE-298, D-penicillamine, bucillamine and auranofin on the proliferation of murine lymphocytes, and the production of nitric oxide by murine macrophages.

International immunopharmacology 20010501

A case of BOOP developed during bucillamine treatment for rheumatoid.

The Korean journal of internal medicine 20010301

Drug-induced pemphigus foliaceus with features of pemphigus vulgaris.

The British journal of dermatology 20010201

Novel therapy in the treatment of scleroderma.

Expert opinion on investigational drugs 20010101

Subcorneal pustular dermatosis-type IgA pemphigus induced by thiol drugs.

European journal of dermatology : EJD 20010101

[A case of drug-induced interstitial pneumonitis in rheumatoid arthritis treated with bucillamine].

Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20010101

Cutaneous drug reaction case reports: from the world literature.

American journal of clinical dermatology 20010101

[Clinicopathological study of nephropathy in patients with rheumatoid arthritis].

Ryumachi. [Rheumatism] 19910201

Serum oxidation activities and rheumatoid arthritis.

International journal of tissue reactions 19870101