Home Other Building Blocks Sulbactum Sodium

Sulbactum Sodium

CAS No.:
63-38-7
Catalog Number:
AG00E9M9
Molecular Formula:
C9H15N3O11P2
Molecular Weight:
403.1764
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Product Description
Catalog Number:
AG00E9M9
Chemical Name:
Sulbactum Sodium
CAS Number:
63-38-7
Molecular Formula:
C9H15N3O11P2
Molecular Weight:
403.1764
MDL Number:
MFCD00066486
IUPAC Name:
[(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphono hydrogen phosphate
InChI:
InChI=1S/C9H15N3O11P2/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H2,10,11,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
InChI Key:
ZWIADYZPOWUWEW-XVFCMESISA-N
SMILES:
O[C@@H]1[C@@H](COP(=O)(OP(=O)(O)O)O)O[C@H]([C@@H]1O)n1ccc(nc1=O)N
EC Number:
200-557-1
UNII:
1ZH821MXU5
Properties
Complexity:
690  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Defined Bond Stereocenter Count:
0
Exact Mass:
403.018g/mol
Formal Charge:
0
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
11  
Hydrogen Bond Donor Count:
6  
Isotope Atom Count:
0
Molecular Weight:
403.177g/mol
Monoisotopic Mass:
403.018g/mol
Rotatable Bond Count:
6  
Topological Polar Surface Area:
222A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-4.5  
Literature
Title Journal
Characterization of the CDP-D-mannitol biosynthetic pathway in Streptococcus pneumoniae 35A. Glycobiology 20121201
Tangled up in knots: structures of inactivated forms of E. coli class Ia ribonucleotide reductase. Structure (London, England : 1993) 20120808
Role of arginine 293 and glutamine 288 in communication between catalytic and allosteric sites in yeast ribonucleotide reductase. Journal of molecular biology 20120622
Biochemical characterization of the CDP-D-arabinitol biosynthetic pathway in Streptococcus pneumoniae 17F. Journal of bacteriology 20120401
Metabolism and regulation of glycerolipids in the yeast Saccharomyces cerevisiae. Genetics 20120201
CDP-diacylglycerol phospholipid synthesis in detergent-soluble, non-raft, membrane microdomains of the endoplasmic reticulum. Journal of lipid research 20111201
The antihyperalgesic effect of cytidine-5'-diphosphate-choline in neuropathic and inflammatory pain models. Behavioural pharmacology 20110901
High-throughput, homogeneous, fluorescence intensity-based measurement of adenosine diphosphate and other ribonucleoside diphosphates with nanomolar sensitivity. Analytical biochemistry 20110815
Ligand chirality effects on the dynamics of human 3-phosphoglycerate kinase: comparison between D- and L-nucleotides. Archives of biochemistry and biophysics 20110701
Unique self-anhydride formation in the degradation of cytidine-5'-monophosphosialic acid (CMP-Neu5Ac) and cytidine-5'-diphosphosialic acid (CDP-Neu5Ac) and its application in CMP-sialic acid analogue synthesis. Chemistry (Weinheim an der Bergstrasse, Germany) 20110627
Profile of nucleotides and nucleosides in Taiwanese human milk. Pediatrics and neonatology 20110401
Use of 2,3,5-F(3)Y-β2 and 3-NH(2)Y-α2 to study proton-coupled electron transfer in Escherichia coli ribonucleotide reductase. Biochemistry 20110301
Lipid pathway alterations in Parkinson's disease primary visual cortex. PloS one 20110101
Path finding methods accounting for stoichiometry in metabolic networks. Genome biology 20110101
Gene coexpression clusters and putative regulatory elements underlying seed storage reserve accumulation in Arabidopsis. BMC genomics 20110101
CGDEase, a Pseudomonas fluorescens protein of the PLC/APase superfamily with CDP-ethanolamine and (dihexanoyl)glycerophosphoethanolamine hydrolase activity induced by osmoprotectants under phosphate-deficient conditions. Molecular microbiology 20101201
Short-term administration of uridine increases brain membrane phospholipid precursors in healthy adults: a 31-phosphorus magnetic resonance spectroscopy study at 4T. Bipolar disorders 20101201
Plasmodium CDP-DAG synthase: an atypical gene with an essential N-terminal extension. International journal for parasitology 20100901
Homology modeling of Mycobacterium tuberculosis 2C-methyl-D-erythritol-4-phosphate cytidylyltransferase, the third enzyme in the MEP pathway for isoprenoid biosynthesis. Journal of molecular modeling 20100601
Neurochemical alterations in methamphetamine-dependent patients treated with cytidine-5'-diphosphate choline: a longitudinal proton magnetic resonance spectroscopy study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100401
Antidepressant stimulation of CDP-diacylglycerol synthesis does not require monoamine reuptake inhibition. BMC neuroscience 20100101
Insight into the mechanism of inactivation of ribonucleotide reductase by gemcitabine 5'-diphosphate in the presence or absence of reductant. Biochemistry 20091215
Mechanism of inactivation of human ribonucleotide reductase with p53R2 by gemcitabine 5'-diphosphate. Biochemistry 20091215
Cardiolipin molecular species with shorter acyl chains accumulate in Saccharomyces cerevisiae mutants lacking the acyl coenzyme A-binding protein Acb1p: new insights into acyl chain remodeling of cardiolipin. The Journal of biological chemistry 20091002
Elimination of the CDP-ethanolamine pathway disrupts hepatic lipid homeostasis. The Journal of biological chemistry 20091002
The development of a metabolic disease phenotype in CTP:phosphoethanolamine cytidylyltransferase-deficient mice. The Journal of biological chemistry 20090918
Choline or CDP-choline alters serum lipid responses to endotoxin in dogs and rats: involvement of the peripheral nicotinic acetylcholine receptors. Shock (Augusta, Ga.) 20090901
The wall teichoic acid polymerase TagF is non-processive in vitro and amenable to study using steady state kinetic analysis. The Journal of biological chemistry 20090807
Cardiolipin biosynthesis and remodeling enzymes are altered during development of heart failure. Journal of lipid research 20090801
The ADP-dependent sugar kinase family: kinetic and evolutionary aspects. IUBMB life 20090701
The effect of peripherally administered CDP-choline in an acute inflammatory pain model: the role of alpha7 nicotinic acetylcholine receptor. Anesthesia and analgesia 20090501
Structure of the nucleotide radical formed during reaction of CDP/TTP with the E441Q-alpha2beta2 of E. coli ribonucleotide reductase. Journal of the American Chemical Society 20090114
Stimulation of the human CTP:phosphoethanolamine cytidylyltransferase gene by early growth response protein 1. Journal of lipid research 20081001
CDP-choline prevents cardiac arrhythmias and lethality induced by short-term myocardial ischemia-reperfusion injury in the rat: involvement of central muscarinic cholinergic mechanisms. Naunyn-Schmiedeberg's archives of pharmacology 20080901
Phosphatidylserine and phosphatidylethanolamine in mammalian cells: two metabolically related aminophospholipids. Journal of lipid research 20080701
Mn2+-dependent ADP-ribose/CDP-alcohol pyrophosphatase: a novel metallophosphoesterase family preferentially expressed in rodent immune cells. The Biochemical journal 20080701
Functional and structural characterization of DR_0079 from Deinococcus radiodurans, a novel Nudix hydrolase with a preference for cytosine (deoxy)ribonucleoside 5'-Di- and triphosphates. Biochemistry 20080624
Diverse antidepressants increase CDP-diacylglycerol production and phosphatidylinositide resynthesis in depression-relevant regions of the rat brain. BMC neuroscience 20080101
Separation of cytidine 5'-triphosphate biosynthesized from cytidine 5'-monophosphate on ion-exchange resin and HPLC analysis of cytidine compounds. Applied biochemistry and biotechnology 20080101
New efficient synthesis of nucleoside diphosphate glycopyranoses. Nucleic acids symposium series (2004) 20080101
The CDP-ethanolamine pathway and phosphatidylserine decarboxylation generate different phosphatidylethanolamine molecular species. The Journal of biological chemistry 20070928
Unusual transformations in the biosynthesis of the antibiotic phosphinothricin tripeptide. Nature chemical biology 20070801
Nucleotide binding to human UMP-CMP kinase using fluorescent derivatives -- a screening based on affinity for the UMP-CMP binding site. The FEBS journal 20070701
Identification and characterization of human ethanolaminephosphotransferase1. Journal of lipid research 20070301
Intraperitoneal administration of CDP-choline and its cholinergic and pyrimidinergic metabolites induce hyperglycemia in rats: involvement of the sympathoadrenal system. Archives of physiology and biochemistry 20070101
Azacytidine (Vidaza(R)) in the treatment of myelodysplastic syndromes. Therapeutics and clinical risk management 20061201
The antinociceptive effects of centrally administered CDP-choline on acute pain models in rats: the involvement of cholinergic system. Brain research 20061030
Structure-activity relationships of uridine 5'-diphosphate analogues at the human P2Y6 receptor. Journal of medicinal chemistry 20060907
Histidine 89 is an essential residue for Hsp70 in the phosphate transfer reaction. Cell stress & chaperones 20060601
Identification and characterization of human cardiolipin synthase. FEBS letters 20060529
Vegetable lipid sources affect in vitro biosynthesis of triacylglycerols and phospholipids in the intestine of sea bream (Sparus aurata). The British journal of nutrition 20060301
Intravenous administration of choline or cdp-choline improves platelet count and platelet closure times in endotoxin-treated dogs. Shock (Augusta, Ga.) 20060101
A new SNP in the promoter region of the porcine MYF5 gene has no effect on its transcript level in m. longissimus dorsi. Journal of applied genetics 20060101
Metabolic engineering of microbes for oligosaccharide and polysaccharide synthesis. Microbial cell factories 20060101
Disruption of the phosphatidylserine decarboxylase gene in mice causes embryonic lethality and mitochondrial defects. The Journal of biological chemistry 20051202
[Determination of cytidine triphosphate and related compound triphos and related compounds in the liquid of enzymatical reaction by high performance liquid chromatography]. Se pu = Chinese journal of chromatography 20050901
Interaction centres of pyrimidine nucleotides: cytidine-5'-diphosphate (CDP) and cytidine-5'-triphosphate (CTP) in their reactions with tetramines and Cu(II) ions. Journal of inorganic biochemistry 20050801
Regulation of gene expression by lithium and depletion of inositol in slices of adult rat cortex. Neuron 20050324
The enantioselectivities of the active and allosteric sites of mammalian ribonucleotide reductase. The FEBS journal 20050301
Living donor liver transplantation for hepatocellular carcinoma: a special reference to a preoperative des-gamma-carboxy prothrombin value. Transplantation proceedings 20050301
Dietary uridine-5'-monophosphate supplementation increases potassium-evoked dopamine release and promotes neurite outgrowth in aged rats. Journal of molecular neuroscience : MN 20050101
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae. Biochimica et biophysica acta 20041108
Elevated erythrocyte CDP-choline levels associated with beta-thalassaemia in patients with transfusion independent anaemia. Nucleosides, nucleotides & nucleic acids 20041001
Enhancement by effectors and substrate nucleotides of R1-R2 interactions in Escherichia coli class Ia ribonucleotide reductase. The Journal of biological chemistry 20040723
Phospholipid metabolism regulated by a transcription factor sensing phosphatidic acid. Science (New York, N.Y.) 20040611
Regulation of phospholipid synthesis in Saccharomyces cerevisiae by zinc. The Journal of biological chemistry 20040521
Control of the CDPethanolamine pathway in mammalian cells: effect of CTP:phosphoethanolamine cytidylyltransferase overexpression and the amount of intracellular diacylglycerol. The Biochemical journal 20040501
Peripheral inflammation increases phosphoinositide activity in the rat dorsal horn. Brain research 20040402
Regulation of phospholipid synthesis in the yeast cki1Delta eki1Delta mutant defective in the Kennedy pathway. The Cho1-encoded phosphatidylserine synthase is regulated by mRNA stability. The Journal of biological chemistry 20040326
Centrally injected CDP-choline increases plasma vasopressin levels by central cholinergic activation. Fundamental & clinical pharmacology 20040201
Phospholipid biosynthesis in mammalian cells. Biochemistry and cell biology = Biochimie et biologie cellulaire 20040201
C. trachomatis-infection accelerates metabolism of phosphatidylcholine derived from low density lipoprotein but does not affect phosphatidylcholine secretion from hepatocytes. BMC microbiology 20040101
Hybridomas expressing gammadelta T-cell receptors respond to cardiolipin and beta2-glycoprotein 1 (apolipoprotein H). Scandinavian journal of immunology 20030901
Alpha-phosphono lactone analogues of cytidine and cytosine arabinoside diphosphates: synthesis via ring closing metathesis. The Journal of organic chemistry 20030822
Multiple brain abscesses caused by Fusobacterium nucleatum treated conservatively. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20030801
Synthesis and properties of 11-(3,5-di-tert-butyl-2-hydroxyphenylcarbamoyl)undecanoic acid, a new amphiphilic antioxidant. Bioorganic & medicinal chemistry letters 20030324
Comprehensive model for allosteric regulation of mammalian ribonucleotide reductase: refinements and consequences. Biochemistry 20030218
Characterization of the redox properties of poplar glutaredoxin. Antioxidants & redox signaling 20030201
Synthesis of 2'-deuterio and 3'-deuterio cytidine 5'-diphosphate. Nucleosides, nucleotides & nucleic acids 20030101
Cytidine diphosphate-diacylglycerol synthesis in Mycobacterium smegmatis. The Biochemical journal 20021001
Comparative study of the effects of short- and long-term ethanol treatment and alcohol withdrawal on phospholipid biosynthesis in rat hepatocytes. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20020301
The conserved active site asparagine in class I ribonucleotide reductase is essential for catalysis. The Journal of biological chemistry 20020222
Sugar specificity of bacterial CMP kinases as revealed by crystal structures and mutagenesis of Escherichia coli enzyme. Journal of molecular biology 20020201
Rapid photolytic release of cytidine 5'-diphosphate from a coumarin derivative: a new tool for the investigation of ribonucleotide reductases. Bioorganic & medicinal chemistry 20020101
Time and sequence dependence of hydroxyurea in combination with gemcitabine in human KB cells. Anticancer research 20020101
Identification of minor metabolites of phospholipid signal molecules in [(32)P]P(i)-labelled platelets. Platelets 20020101
Phosphatidylglycerophosphate synthases from Arabidopsis thaliana. FEBS letters 20011207
Yeast cys3 and gsh1 mutant cells display overlapping but non-identical symptoms of oxidative stress with regard to subcellular protein localization and CDP-DAG metabolism. Molecular genetics and genomics : MGG 20011101
Tissue-specific and developmental effects of the easily shocked mutation on ethanolamine kinase activity and phospholipid composition in Drosophila melanogaster. Biochemical genetics 20011001
The structure of CMP:2-keto-3-deoxy-manno-octonic acid synthetase and of its complexes with substrates and substrate analogs. Journal of molecular biology 20010907
Structure of 4-diphosphocytidyl-2-C- methylerythritol synthetase involved in mevalonate- independent isoprenoid biosynthesis. Nature structural biology 20010701
SKF83959 exhibits biochemical agonism by stimulating [(35)S]GTP gamma S binding and phosphoinositide hydrolysis in rat and monkey brain. Neuropharmacology 20010501
Structure of a sialic acid-activating synthetase, CMP-acylneuraminate synthetase in the presence and absence of CDP. The Journal of biological chemistry 20010316
Mouse ribonucleotide reductase control: influence of substrate binding upon interactions with allosteric effectors. The Journal of biological chemistry 20010309
Overexpression of a mammalian ethanolamine-specific kinase accelerates the CDP-ethanolamine pathway. The Journal of biological chemistry 20010119
The serine protease and RNA-stimulated nucleoside triphosphatase and RNA helicase functional domains of dengue virus type 2 NS3 converge within a region of 20 amino acids. Journal of virology 19990401
Characterization of 2',3'-dideoxycytidine diphosphocholine and 2',3'-dideoxycytidine diphosphoethanolamine. Prominent phosphodiester metabolites of the anti-HIV nucleoside 2',3'-dideoxycytidine. Drug metabolism and disposition: the biological fate of chemicals 19930101
Herpes simplex virus type 1 ribonucleotide reductase: selective and synergistic inactivation by A1110U and its iron complex. Biochemical pharmacology 19900215
Phosphorylation, anti-HIV activity and cytotoxicity of 3'-fluorothymidine. Biochemical and biophysical research communications 19880616
Properties