Decursin
| Title | Journal |
|---|---|
| Effect of decursin on the pharmacokinetics of theophylline and its metabolites in rats. | Journal of ethnopharmacology 20121121 |
| A synthetic decursin analog with increased in vivo stability suppresses androgen receptor signaling in vitro and in vivo. | Investigational new drugs 20121001 |
| Effect of decursinol angelate on the pharmacokinetics of theophylline and its metabolites in rats. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20121001 |
| Ultrafine Angelica gigas powder normalizes ovarian hormone levels and has antiosteoporosis properties in ovariectomized rats: particle size effect. | Journal of medicinal food 20121001 |
| A novel derivative of decursin, CSL-32, blocks migration and production of inflammatory mediators and modulates PI3K and NF-κB activities in HT1080 cells. | Cell biology international 20120701 |
| Decursin, an active compound isolated from Angelica gigas, inhibits fat accumulation, reduces adipocytokine secretion and improves glucose tolerance in mice fed a high-fat diet. | Phytotherapy research : PTR 20120501 |
| Overexpression of cinnamate 4-hydroxylase gene enhances biosynthesis of decursinol angelate in Angelica gigas hairy roots. | Molecular biotechnology 20120201 |
| Quantitative determination of decursin, decursinol angelate, and decursinol in mouse plasma and tumor tissue using liquid-liquid extraction and HPLC. | Planta medica 20120201 |
| Structure-activity relationships for naturally occurring coumarins as β-secretase inhibitor. | Bioorganic & medicinal chemistry 20120115 |
| Pharmacokinetic characterization of decursinol derived from Angelica gigas Nakai in rats. | Xenobiotica; the fate of foreign compounds in biological systems 20111001 |
| Decursin from Angelicagigas Nakai induces apoptosis in RC-58T/h/SA#4 primary human prostate cancer cells via a mitochondria-related caspase pathway. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20111001 |
| Decursin chemosensitizes human multiple myeloma cells through inhibition of STAT3 signaling pathway. | Cancer letters 20110201 |
| Protective effects of decursin and decursinol angelate against amyloid β-protein-induced oxidative stress in the PC12 cell line: the role of Nrf2 and antioxidant enzymes. | Bioscience, biotechnology, and biochemistry 20110101 |
| Inhibition of cyclooxygenase-2-dependent survivin mediates decursin-induced apoptosis in human KBM-5 myeloid leukemia cells. | Cancer letters 20101208 |
| Decursinol angelate blocks transmigration and inflammatory activation of cancer cells through inhibition of PI3K, ERK and NF-kappaB activation. | Cancer letters 20101001 |
| Cloning and characterization of phenylalanine ammonia-lyase and cinnamate 4-hydroxylase and pyranocoumarin biosynthesis in Angelica gigas. | Journal of natural products 20100827 |
| Hypopigmentary action of dihydropyranocoumarin D2, a decursin derivative, as a MITF-degrading agent. | Journal of natural products 20100528 |
| Decursin prevents cisplatin-induced apoptosis via the enhancement of antioxidant enzymes in human renal epithelial cells. | Biological & pharmaceutical bulletin 20100101 |
| Decursin inhibits VEGF-mediated inner blood-retinal barrier breakdown by suppression of VEGFR-2 activation. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20090901 |
| Effects of diumancal and decursinol on 5-hydroxytryptamine level in rat brain. | Georgian medical news 20090901 |
| Scuteflorins A and B, dihydropyranocoumarins from Scutellaria lateriflora. | Journal of natural products 20090601 |
| The analgesic effect of decursinol. | Archives of pharmacal research 20090601 |
| A novel (S)-(+)-decursin derivative, (S)-(+)-3-(3,4-dihydroxy-phenyl)-acrylic acid 2,2-dimethyl-8-oxo-3,4-dihydro-2H,8H-pyrano[3,2-g]chromen-3-yl-ester, inhibits ovalbumin-induced lung inflammation in a mouse model of asthma. | Biological & pharmaceutical bulletin 20090301 |
| In vivo anti-cancer activity of Korean Angelica gigas and its major pyranocoumarin decursin. | The American journal of Chinese medicine 20090101 |
| Decursin inhibits retinal neovascularization via suppression of VEGFR-2 activation. | Molecular vision 20090101 |
| Androgen receptor functional analyses by high throughput imaging: determination of ligand, cell cycle, and mutation-specific effects. | PloS one 20080101 |
| Decursin and decursinol angelate selectively inhibit NADH-fumarate reductase of Ascaris suum. | Planta medica 20071101 |
| Mechanism-based inactivation of cytochrome P450 2A6 by decursinol angelate isolated from Angelica Gigas. | Drug metabolism and disposition: the biological fate of chemicals 20071001 |
| Oriental herbs as a source of novel anti-androgen and prostate cancer chemopreventive agents. | Acta pharmacologica Sinica 20070901 |
| Decursinol and decursin protect primary cultured rat cortical cells from glutamate-induced neurotoxicity. | The Journal of pharmacy and pharmacology 20070601 |
| A novel class of pyranocoumarin anti-androgen receptor signaling compounds. | Molecular cancer therapeutics 20070301 |
| [Inhibitory effects of 11 coumarin compounds against growth of human bladder carcinoma cell line E-J in vitro]. | Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20070101 |
| Decursin and decursinol angelate inhibit estrogen-stimulated and estrogen-independent growth and survival of breast cancer cells. | Breast cancer research : BCR 20070101 |
| Decursin inhibits induction of inflammatory mediators by blocking nuclear factor-kappaB activation in macrophages. | Molecular pharmacology 20060601 |
| Molecular target of decursins in the inhibition of lipid droplet accumulation in macrophages. | Biological & pharmaceutical bulletin 20060501 |
| Potent antiandrogen and androgen receptor activities of an Angelica gigas-containing herbal formulation: identification of decursin as a novel and active compound with implications for prevention and treatment of prostate cancer. | Cancer research 20060101 |
| Decursin and PDBu: two PKC activators distinctively acting in the megakaryocytic differentiation of K562 human erythroleukemia cells. | Leukemia research 20051201 |
| Involvement of PKC and ROS in the cytotoxic mechanism of anti-leukemic decursin and its derivatives and their structure-activity relationship in human K562 erythroleukemia and U937 myeloleukemia cells. | Cancer letters 20050608 |
| A novel anticancer agent, decursin, induces G1 arrest and apoptosis in human prostate carcinoma cells. | Cancer research 20050201 |
| Four new neuroprotective dihydropyranocoumarins from Angelica gigas. | Journal of natural products 20050101 |
| Protection against beta-amyloid peptide-induced memory impairment with long-term administration of extract of Angelica gigas or decursinol in mice. | Progress in neuro-psychopharmacology & biological psychiatry 20040101 |
| Platelet anti-aggregatory effects of coumarins from the roots of Angelica genuflexa and A. gigas. | Archives of pharmacal research 20030901 |
| Anti-tumor activities of decursinol angelate and decursin from Angelica gigas. | Archives of pharmacal research 20030901 |
| Antinociceptive mechanisms of orally administered decursinol in the mouse. | Life sciences 20030613 |
| Effects of ginsenoside Rd and decursinol on the neurotoxic responses induced by kainic acid in mice. | Planta medica 20030301 |
| Decursin from Angelica gigas mitigates amnesia induced by scopolamine in mice. | Neurobiology of learning and memory 20030101 |
| Coumarins isolated from Angelica gigas inhibit acetylcholinesterase: structure-activity relationships. | Journal of natural products 20010501 |