Asenapine
Title | Journal |
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Serotonin 5-HT6 receptor antagonists for the treatment of cognitive deficiency in Alzheimer's disease. | Journal of medicinal chemistry 20140911 |
Newer antipsychotics and upcoming molecules for schizophrenia. | European journal of clinical pharmacology 20130801 |
Asenapine for the treatment of manic and mixed episodes associated with bipolar I disorder: from clinical research to clinical practice. | Expert opinion on pharmacotherapy 20130301 |
Asenapine, iloperidone and lurasidone: critical appraisal of the most recently approved pharmacotherapies for schizophrenia in adults. | Expert review of clinical pharmacology 20130101 |
Development and validation of automated SPE-HPLC-MS/MS methods for the quantification of asenapine, a new antipsychotic agent, and its two major metabolites in human urine. | Biomedical chromatography : BMC 20121201 |
New serotonin/dopamine antagonists for the treatment of schizophrenia: are we making real progress? | Clinical schizophrenia & related psychoses 20121001 |
Pharmacological and clinical profile of recently approved second-generation antipsychotics: implications for treatment of schizophrenia in older patients. | Drugs & aging 20121001 |
Iloperidone, asenapine and lurasidone: a primer on their current status. | Expert opinion on pharmacotherapy 20120901 |
Body weight and metabolic adverse effects of asenapine, iloperidone, lurasidone and paliperidone in the treatment of schizophrenia and bipolar disorder: a systematic review and exploratory meta-analysis. | CNS drugs 20120901 |
Clinically important differences in the pharmacokinetics of the ten newer 'atypical' antipsychotics: Part 2. Metabolism and elimination. | Journal of psychiatric practice 20120901 |
A systematic review of meta-analyses of the efficacy of oral atypical antipsychotics for the treatment of adult patients with schizophrenia. | Expert opinion on pharmacotherapy 20120801 |
Involvement of 5-HT2A receptor and α2-adrenoceptor blockade in the asenapine-induced elevation of prefrontal cortical monoamine outflow. | Synapse (New York, N.Y.) 20120701 |
Long-term efficacy and safety of asenapine or olanzapine in patients with schizophrenia or schizoaffective disorder: an extension study. | Pharmacopsychiatry 20120701 |
Weight gain and glucose dysregulation with second-generation antipsychotics and antidepressants: a review for primary care physicians. | Postgraduate medicine 20120701 |
▼Asenapine for bipolar I disorder? | Drug and therapeutics bulletin 20120601 |
[Asenapine in bipolar disorder: efficacy, safety and place in clinical practice]. | L'Encephale 20120601 |
Summary of the comparative effectiveness review on off-label use of atypical antipsychotics. | Journal of managed care pharmacy : JMCP 20120601 |
Valproate reduces the glucuronidation of asenapine without affecting asenapine plasma concentrations. | Journal of clinical pharmacology 20120501 |
Short-term safety and pharmacokinetic profile of asenapine in older patients with psychosis. | International journal of geriatric psychiatry 20120501 |
Asenapine: a clinical review of a second-generation antipsychotic. | Clinical therapeutics 20120501 |
Clinically important differences in the pharmacokinetics of the ten newer 'atypical' antipsychotics: part 1. | Journal of psychiatric practice 20120501 |
Allergic reactions and sudden death with asenapine. | The Journal of clinical psychiatry 20120501 |
Asenapine effects on cognitive and monoamine dysfunction elicited by subchronic phencyclidine administration. | Neuropharmacology 20120301 |
[Antipsychotic medications for bipolar I disorders. New atypical neuroleptic drug asenapine approved]. | Der Nervenarzt 20120301 |
Interactions between antiepileptics and second-generation antipsychotics. | Expert opinion on drug metabolism & toxicology 20120301 |
Quantification of asenapine and three metabolites in human plasma using liquid chromatography-tandem mass spectrometry with automated solid-phase extraction: application to a phase I clinical trial with asenapine in healthy male subjects. | Biomedical chromatography : BMC 20120201 |
Asenapine as adjunctive treatment for acute mania associated with bipolar disorder: results of a 12-week core study and 40-week extension. | Journal of clinical psychopharmacology 20120201 |
Asenapine versus olanzapine in people with persistent negative symptoms of schizophrenia. | Journal of clinical psychopharmacology 20120201 |
The psychopharmacology of agitation: consensus statement of the american association for emergency psychiatry project Beta psychopharmacology workgroup. | The western journal of emergency medicine 20120201 |
Asenapine: a synthesis of efficacy data in bipolar mania and schizophrenia. | Clinical schizophrenia & related psychoses 20120101 |
The neuroprotective disease-modifying potential of psychotropics in Parkinson's disease. | Parkinson's disease 20120101 |
Update on the role of antipsychotics in the treatment of Tourette syndrome. | Neuropsychiatric disease and treatment 20120101 |
Critical appraisal of lurasidone in the management of schizophrenia. | Neuropsychiatric disease and treatment 20120101 |
Atypical antipsychotic drugs, schizophrenia, and metabolic syndrome in non-Euro-American societies. | Clinical neuropharmacology 20120101 |
Safety and tolerability of switching to asenapine from other antipsychotic agents: pooled results from two randomized multicenter trials in stable patients with persistent negative symptoms in schizophrenia. | Neuropsychiatric disease and treatment 20120101 |
Stability-indicating liquid chromatographic method for the quantification of the new antipsychotic agent asenapine in bulk and in pharmaceutical formulation. | Scientia pharmaceutica 20120101 |
Smoking and metabolism; asenapine; irreversible MAOIs. | Psychosomatics 20120101 |
Asenapine: a review of acute and extension phase data in bipolar disorder. | CNS neuroscience & therapeutics 20111201 |
System for disclosing hospitality should be transparent. | BMJ (Clinical research ed.) 20111115 |
Long-Term Assessment of Asenapine vs. Olanzapine in Patients with Schizophrenia or Schizoaffective Disorder. | Pharmacopsychiatry 20111101 |
Comparative efficacy and acceptability of antimanic drugs in acute mania: a multiple-treatments meta-analysis. | Lancet (London, England) 20111008 |
Attenuation of chronic mild stress-induced 'anhedonia' by asenapine is not associated with a 'hedonic' profile in intracranial self-stimulation. | Journal of psychopharmacology (Oxford, England) 20111001 |
Biological perspectives: update on newer antipsychotic drugs: are they evidence based? | Perspectives in psychiatric care 20111001 |
Asenapine: a new antipsychotic option. | Journal of pharmacy practice 20111001 |
Efficacy and comparative effectiveness of atypical antipsychotic medications for off-label uses in adults: a systematic review and meta-analysis. | JAMA 20110928 |
Functional potencies of dopamine agonists and antagonists at human dopamine D₂ and D₃ receptors. | European journal of pharmacology 20110901 |
Suicidal ideation associated with asenapine use: a report of 2 cases. | Journal of clinical psychopharmacology 20110801 |
Asenapine pharmacokinetics in hepatic and renal impairment. | Clinical pharmacokinetics 20110701 |
Unmet treatment needs in schizophrenia patients: is asenapine a potential therapeutic option? | Expert review of neurotherapeutics 20110701 |
Asenapine for the treatment of stuttering: an analysis of three cases. | The American journal of psychiatry 20110601 |
Asenapine improves phencyclidine-induced object recognition deficits in the rat: evidence for engagement of a dopamine D1 receptor mechanism. | Psychopharmacology 20110401 |
Metabolism and excretion of asenapine in healthy male subjects. | Drug metabolism and disposition: the biological fate of chemicals 20110401 |
Dual inhibition: a novel promising pharmacological approach for different disease conditions. | The Journal of pharmacy and pharmacology 20110401 |
Update on newer antipsychotic drugs. | Journal of psychosocial nursing and mental health services 20110401 |
Newer molecules in the treatment of schizophrenia: A clinical update. | Indian journal of pharmacology 20110401 |
Dopamine D2 occupancy as a biomarker for antipsychotics: quantifying the relationship with efficacy and extrapyramidal symptoms. | The AAPS journal 20110301 |
Asenapine: a review of its use in the management of mania in adults with bipolar I disorder. | CNS drugs 20110301 |
A randomized placebo-controlled trial of asenapine for the prevention of relapse of schizophrenia after long-term treatment. | The Journal of clinical psychiatry 20110301 |
Iloperidone, asenapine, and lurasidone: a brief overview of 3 new second-generation antipsychotics. | Postgraduate medicine 20110301 |
The role of serotonin receptors in the action of atypical antipsychotic drugs. | Current opinion in pharmacology 20110201 |
Efficacy of antimanic treatments: meta-analysis of randomized, controlled trials. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20110101 |
Comparison of QTc data analysis methods recommended by the ICH E14 guidance and exposure-response analysis: case study of a thorough QT study of asenapine. | Clinical pharmacology and therapeutics 20110101 |
Atypical antipsychotics: the two new arrivals. | Issues in mental health nursing 20110101 |
Paliperidone ER and oral risperidone in patients with schizophrenia: a comparative database analysis. | BMC psychiatry 20110101 |
Weight gain, obesity, and psychotropic prescribing. | Journal of obesity 20110101 |
Class effect of pharmacotherapy in bipolar disorder: fact or misbelief? | Annals of general psychiatry 20110101 |
The role of asenapine in the treatment of manic or mixed states associated with bipolar I disorder. | Neuropsychiatric disease and treatment 20110101 |
Role of sublingual asenapine in treatment of schizophrenia. | Neuropsychiatric disease and treatment 20110101 |
Effects of asenapine on depressive symptoms in patients with bipolar I disorder experiencing acute manic or mixed episodes: a post hoc analysis of two 3-week clinical trials. | BMC psychiatry 20110101 |
Clinical potential of lurasidone in the management of schizophrenia. | Therapeutics and clinical risk management 20110101 |
Review of the safety, efficacy, and side effect profile of asenapine in the treatment of bipolar 1 disorder. | Patient preference and adherence 20110101 |
Clinical utility of the risperidone formulations in the management of schizophrenia. | Neuropsychiatric disease and treatment 20110101 |
Asenapine: a clinical overview. | The Journal of clinical psychiatry 20110101 |
Effects of asenapine, olanzapine, and risperidone on psychotomimetic-induced reversal-learning deficits in the rat. | Behavioural brain research 20101225 |
A review of new atypical antipsychotic launches in the United States. | Psychiatry (Edgmont (Pa. : Township)) 20101201 |
Asenapine for long-term treatment of bipolar disorder: a double-blind 40-week extension study. | Journal of affective disorders 20101101 |
Effects of asenapine on prefrontal N-methyl-D-aspartate receptor-mediated transmission: involvement of dopamine D1 receptors. | Synapse (New York, N.Y.) 20101101 |
Adjunctive use of atypical antipsychotics for treatment-resistant generalized anxiety disorder. | Pharmacotherapy 20100901 |
New antipsychotic drugs: how do their receptor-binding profiles compare? | The Journal of clinical psychiatry 20100901 |
Evaluation of the clinical efficacy of asenapine in schizophrenia. | Expert opinion on pharmacotherapy 20100801 |
Effect of absorption site on the pharmacokinetics of sublingual asenapine in healthy male subjects. | Biopharmaceutics & drug disposition 20100701 |
Long-term assessment of Asenapine vs. Olanzapine in patients with schizophrenia or schizoaffective disorder. | Pharmacopsychiatry 20100601 |
Pharmacology and efficacy of asenapine for manic and mixed states in adults with bipolar disorder. | Expert review of neurotherapeutics 20100501 |
Repeated effects of asenapine on adrenergic and cholinergic muscarinic receptors. | The international journal of neuropsychopharmacology 20100401 |
Asenapine in the treatment of acute mania in bipolar I disorder: a randomized, double-blind, placebo-controlled trial. | Journal of affective disorders 20100401 |
Efficacy and safety of asenapine in a placebo- and haloperidol-controlled trial in patients with acute exacerbation of schizophrenia. | Journal of clinical psychopharmacology 20100401 |
Asenapine induces differential regional effects on serotonin receptor subtypes. | Journal of psychopharmacology (Oxford, England) 20100301 |
New drug information. Saphris. | JAAPA : official journal of the American Academy of Physician Assistants 20100301 |
Asenapine (Saphris) sublingual tablets for schizophrenia and bipolar disorder. | The Medical letter on drugs and therapeutics 20100208 |
New drugs: asenapine, iloperidone, and bepotastine besilate. | Journal of the American Pharmacists Association : JAPhA 20100101 |
A genetic network model of cellular responses to lithium treatment and cocaine abuse in bipolar disorder. | BMC systems biology 20100101 |
[The quest for the pharmacological treatment of schizophrenia: from conventional neuroleptics to atypical antipsychotics and beyond]. | Vertex (Buenos Aires, Argentina) 20100101 |
Neuroleptic malignant syndrome after exposure to asenapine: a case report. | Primary care companion to the Journal of clinical psychiatry 20100101 |
Asenapine, a new sublingual atypical antipsychotic. | Journal of pharmacology & pharmacotherapeutics 20100101 |
Asenapine versus olanzapine in acute mania: a double-blind extension study. | Bipolar disorders 20091201 |
Asenapine for schizophrenia and bipolar disorder: a review of the efficacy and safety profile for this newly approved sublingually absorbed second-generation antipsychotic. | International journal of clinical practice 20091201 |
Asenapine maleate: a new drug for the treatment of schizophrenia and bipolar mania. | Drugs of today (Barcelona, Spain : 1998) 20091201 |
Asenapine effects in animal models of psychosis and cognitive function. | Psychopharmacology 20091101 |
A 3-week, randomized, placebo-controlled trial of asenapine in the treatment of acute mania in bipolar mania and mixed states. | Bipolar disorders 20091101 |
Exposure-response analysis in patients with schizophrenia to assess the effect of asenapine on QTc prolongation. | Journal of clinical pharmacology 20091101 |
Asenapine. | Nature reviews. Drug discovery 20091101 |
Asenapine approved for treatment of schizophrenia, bipolar disorder. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20090915 |
Asenapine. | CNS drugs 20090901 |
Modeling and simulation of the time course of asenapine exposure response and dropout patterns in acute schizophrenia. | Clinical pharmacology and therapeutics 20090701 |
Asenapine elevates cortical dopamine, noradrenaline and serotonin release. Evidence for activation of cortical and subcortical dopamine systems by different mechanisms. | Psychopharmacology 20090601 |
Asenapine exerts distinctive regional effects on ionotropic glutamate receptor subtypes in rat brain. | Synapse (New York, N.Y.) 20090501 |
Electrophysiological characterization of the effects of asenapine at 5-HT(1A), 5-HT(2A), alpha(2)-adrenergic and D(2) receptors in the rat brain. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20090301 |
Asenapine: a novel psychopharmacologic agent with a unique human receptor signature. | Journal of psychopharmacology (Oxford, England) 20090101 |
Asenapine restores cognitive flexibility in rats with medial prefrontal cortex lesions. | Psychopharmacology 20090101 |
Asenapine monotherapy in the acute treatment of both schizophrenia and bipolar I disorder. | Neuropsychiatric disease and treatment 20090101 |
Asenapine increases dopamine, norepinephrine, and acetylcholine efflux in the rat medial prefrontal cortex and hippocampus. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20081101 |
Actions of novel agonists, antagonists and antipsychotic agents at recombinant rat 5-HT6 receptors: a comparative study of coupling to G alpha s. | European journal of pharmacology 20080707 |
Acute and long-term treatment of mania. | Dialogues in clinical neuroscience 20080601 |
Bipolar depression: trial-based insights to guide patient care. | Dialogues in clinical neuroscience 20080601 |
American psychiatric association. | P & T : a peer-reviewed journal for formulary management 20080601 |
Differential regional and dose-related effects of asenapine on dopamine receptor subtypes. | Psychopharmacology 20080501 |
Asenapine, a novel psychopharmacologic agent: preclinical evidence for clinical effects in schizophrenia. | Psychopharmacology 20080201 |
Efficacy and tolerability of asenapine in acute schizophrenia: a placebo- and risperidone-controlled trial. | The Journal of clinical psychiatry 20071001 |
Drug-drug interactions associated with second-generation antipsychotics: considerations for clinicians and patients. | Psychopharmacology bulletin 20070101 |
Asenapine in the treatment of negative symptoms of schizophrenia: clinical trial design and rationale. | Psychopharmacology bulletin 20070101 |
Actions of ORG 5222 as a novel psychotropic agent. | Pharmacology, biochemistry, and behavior 19900301 |