3-Phenyl-3-(4-(trifluoromethyl)phenoxy)propan-1-amine hydrochloride
| Title | Journal |
|---|---|
| A method for reliable voluntary oral administration of a fixed dosage (mg/kg) of chronic daily medication to rats. | Laboratory animals 20121001 |
| Simultaneous determination of 25 common pharmaceuticals in whole blood using ultra-performance liquid chromatography-tandem mass spectrometry. | Journal of analytical toxicology 20120901 |
| Simultaneous determination of fluoxetine and norfluoxetine enantiomers using isotope discrimination mass spectroscopy solution method and its application in the CYP2C9-mediated stereoselective interactions. | Journal of chromatography. A 20120504 |
| Trace analysis of fluoxetine and its metabolite norfluoxetine. Part II: Enantioselective quantification and studies of matrix effects in raw and treated wastewater by solid phase extraction and liquid chromatography-tandem mass spectrometry. | Journal of chromatography. A 20120302 |
| Therapeutic drug monitoring of children and adolescents treated with fluoxetine. | Pharmacopsychiatry 20120301 |
| Pharmacokinetics of fluoxetine in rhesus macaques following multiple routes of administration. | Pharmacology 20110901 |
| Trace analysis of fluoxetine and its metabolite norfluoxetine. Part I: development of a chiral liquid chromatography-tandem mass spectrometry method for wastewater samples. | Journal of chromatography. A 20110819 |
| S-norfluoxetine microinfused into the basolateral amygdala increases allopregnanolone levels and reduces aggression in socially isolated mice. | Neuropharmacology 20110601 |
| A validated enantioselective assay for the simultaneous quantitation of (R)-, (S)-fluoxetine and (R)-, (S)-norfluoxetine in ovine plasma using liquid chromatography with tandem mass spectrometry (LC/MS/MS). | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110215 |
| The effects of antidepressants on mitochondrial function in a model cell system and isolated mitochondria. | Neurochemical research 20110201 |
| The pH-dependent toxicity of basic pharmaceuticals in the green algae Scenedesmus vacuolatus can be explained with a toxicokinetic ion-trapping model. | Aquatic toxicology (Amsterdam, Netherlands) 20110117 |
| Effect of chronic fluoxetine treatment on male and female rat erythrocyte and prefrontal cortex fatty acid composition. | Progress in neuro-psychopharmacology & biological psychiatry 20101001 |
| Comparative bioavailability and tolerability of a single 20-mg dose of two fluoxetine hydrochloride dispersible tablet formulations in fasting, healthy Chinese male volunteers: an open-label, randomized-sequence, two-period crossover study. | Clinical therapeutics 20101001 |
| Disposition of chiral and racemic fluoxetine and norfluoxetine across childbearing. | Journal of clinical psychopharmacology 20100801 |
| Sequential metabolism of secondary alkyl amines to metabolic-intermediate complexes: opposing roles for the secondary hydroxylamine and primary amine metabolites of desipramine, (s)-fluoxetine, and N-desmethyldiltiazem. | Drug metabolism and disposition: the biological fate of chemicals 20100601 |
| Three-phase, liquid-phase microextraction combined with high performance liquid chromatography-fluorescence detection for the simultaneous determination of fluoxetine and norfluoxetine in human plasma. | Journal of pharmaceutical and biomedical analysis 20100105 |
| Gas chromatography-mass spectrometry detection of a norfluoxetine artifact in hydrolyzed urine samples may falsely indicate tranylcypromine ingestion. | Journal of analytical toxicology 20100101 |
| Unsuspected poor metabolizer phenotypes of fluoxetine in bioavailability/bioequivalence studies from an indian population perspective. Retrospective pharmacokinetic data evaluation. | Arzneimittel-Forschung 20100101 |
| Determination of fluoxetine and norfluoxetine enantiomers in human plasma by polypyrrole-coated capillary in-tube solid-phase microextraction coupled with liquid chromatography-fluorescence detection. | Journal of chromatography. A 20091204 |
| Fluoxetine and norfluoxetine revisited: new insights into the electrochemical and spectroscopic properties. | The journal of physical chemistry. A 20090910 |
| Paradoxical anxiogenic response of juvenile mice to fluoxetine. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090901 |
| Pharmacokinetics and pharmacodynamics of norfluoxetine in rats: Increasing extracellular serotonin level in the frontal cortex. | Pharmacology, biochemistry, and behavior 20090501 |
| Enhanced fear responses in mice treated with anabolic androgenic steroids. | Neuroreport 20090422 |
| SSRIs act as selective brain steroidogenic stimulants (SBSSs) at low doses that are inactive on 5-HT reuptake. | Current opinion in pharmacology 20090201 |
| Norfluoxetine induces spawning and parturition in estuarine and freshwater bivalves. | Bulletin of environmental contamination and toxicology 20081201 |
| Uptake and depuration of the anti-depressant fluoxetine by the Japanese medaka (Oryzias latipes). | Chemosphere 20081201 |
| Fluoxetine inhibition of glycine receptor activity in rat hippocampal neurons. | Brain research 20081106 |
| Neurosteroid biosynthesis regulates sexually dimorphic fear and aggressive behavior in mice. | Neurochemical research 20081001 |
| Fatal intoxication with milnacipran. | Journal of forensic and legal medicine 20080801 |
| Genetic regulation of behavioral and neuronal responses to fluoxetine. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080501 |
| Simultaneous determination of citalopram, fluoxetine and their main metabolites in human urine samples by solid-phase microextraction coupled with high-performance liquid chromatography. | Journal of pharmaceutical and biomedical analysis 20080313 |
| The effects of pH on fluoxetine in Japanese medaka (Oryzias latipes): acute toxicity in fish larvae and bioaccumulation in juvenile fish. | Chemosphere 20080101 |
| Fluoxetine and norfluoxetine analysis by direct injection of human plasma in a column switching liquid chromatographic system. | Journal of separation science 20080101 |
| Hollow-fibre supported liquid membrane extraction for determination of fluoxetine and norfluoxetine concentration at ultra trace level in sewage samples. | Journal of separation science 20071001 |
| Analysis of paroxetine, fluoxetine and norfluoxetine in fish tissues using pressurized liquid extraction, mixed mode solid phase extraction cleanup and liquid chromatography-tandem mass spectrometry. | Journal of chromatography. A 20070907 |
| On-line sample stacking and short-end injection CE for the determination of fluoxetine and norfluoxetine in plasma: Method development and validation using experimental designs. | Electrophoresis 20070901 |
| The distribution of fluoxetine in human fluids and tissues. | Journal of analytical toxicology 20070901 |
| Comparative metabolic capabilities and inhibitory profiles of CYP2D6.1, CYP2D6.10, and CYP2D6.17. | Drug metabolism and disposition: the biological fate of chemicals 20070801 |
| The effects of antidepressants on cyclic AMP-response element-driven gene transcription in a model cell system. | Biochemical pharmacology 20070615 |
| Determination of fluoxetine, norfluoxetine and their enantiomers in rat plasma and brain samples by liquid chromatography with fluorescence detection. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070601 |
| Solid-phase microextraction-liquid chromatography (SPME-LC) determination of fluoxetine and norfluoxetine in plasma using a heated liquid flow through interface. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070301 |
| Evaluation of the influence of protein precipitation prior to on-line SPE-LC-API/MS procedures using multivariate data analysis. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070115 |
| Drug-induced long QT syndrome: hERG K+ channel block and disruption of protein trafficking by fluoxetine and norfluoxetine. | British journal of pharmacology 20061101 |
| Neurosteroids regulate mouse aggression induced by anabolic androgenic steroids. | Neuroreport 20061002 |
| Fluoxetine and norfluoxetine stereospecifically and selectively increase brain neurosteroid content at doses that are inactive on 5-HT reuptake. | Psychopharmacology 20060601 |
| T-type calcium channels are inhibited by fluoxetine and its metabolite norfluoxetine. | Molecular pharmacology 20060601 |
| Lack of pharmacokinetic interaction when switching from fluoxetine to milnacipran. | International clinical psychopharmacology 20060501 |
| Stereoselective disposition of fluoxetine and norfluoxetine during pregnancy and breast-feeding. | British journal of clinical pharmacology 20060201 |
| Comparison of liquid chromatography with fluorescence detection to liquid chromatography-mass spectrometry for the determination of fluoxetine and norfluoxetine in human plasma. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060118 |
| Rapid and direct measurement of free concentrations of highly protein-bound fluoxetine and its metabolite norfluoxetine in plasma. | Rapid communications in mass spectrometry : RCM 20060101 |
| Bioequivalence testing of a new tablet formulation of generic fluoxetine. | European journal of drug metabolism and pharmacokinetics 20060101 |
| Development of a solid phase extraction for 13 'new' generation antidepressants and their active metabolites for gas chromatographic-mass spectrometric analysis. | Journal of chromatography. A 20051209 |
| Influence of CYP2C9, 2C19 and 2D6 genetic polymorphisms on the steady-state plasma concentrations of the enantiomers of fluoxetine and norfluoxetine. | Basic & clinical pharmacology & toxicology 20051101 |
| Norfluoxetine and fluoxetine have similar anticonvulsant and Ca2+ channel blocking potencies. | Brain research bulletin 20050930 |
| The effects of desmethylimipramine on cyclic AMP-stimulated gene transcription in a model cell system. | Biochemical pharmacology 20050901 |
| Liquid chromatographic-mass spectrometric method for the determination of fluoxetine and norfluoxetine in human plasma: application to clinical study. | Farmaco (Societa chimica italiana : 1989) 20050401 |
| Inhibition of the human two-pore domain potassium channel, TREK-1, by fluoxetine and its metabolite norfluoxetine. | British journal of pharmacology 20050301 |
| Relative rectal bioavailability of fluoxetine in normal volunteers. | Journal of clinical psychopharmacology 20050201 |
| Determination of select antidepressants in fish from an effluent-dominated stream. | Environmental toxicology and chemistry 20050201 |
| Bioequivalence study of fluoxetine hydrochloride in healthy volunteers. | Arzneimittel-Forschung 20050101 |
| Effects of fluoxetine on dopamine D2 receptors in the human brain: a positron emission tomography study with [11C]raclopride. | The international journal of neuropsychopharmacology 20041201 |
| Pharmacokinetics/pharmacodynamics of desloratadine and fluoxetine in healthy volunteers. | Journal of clinical pharmacology 20041101 |
| A rapid HPLC-DAD method for the analysis of fluoxetine and norfluoxetine in plasma from overdose patients. | Journal of pharmaceutical and biomedical analysis 20041029 |
| Effects of norfluoxetine on the action potential and transmembrane ion currents in canine ventricular cardiomyocytes. | Naunyn-Schmiedeberg's archives of pharmacology 20040901 |
| Rapid quantitation of fluoxetine and norfluoxetine in serum by micro-disc solid-phase extraction with high-performance liquid chromatography-ultraviolet absorbance detection. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040525 |
| Chronic fluoxetine treatment partly attenuates the long-term anxiety and depressive symptoms induced by MDMA ('Ecstasy') in rats. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040401 |
| Influence of fluoxetine on positive and negative affect in a clinic-based smoking cessation trial. | Psychopharmacology 20040401 |
| Effect of CYP2D6 and CYP2C9 genotypes on fluoxetine and norfluoxetine plasma concentrations during steady-state conditions. | European journal of clinical pharmacology 20040201 |
| Stereoselective pharmacokinetics of fluoxetine and norfluoxetine enantiomers in pregnant sheep. | Drug metabolism and disposition: the biological fate of chemicals 20040201 |
| Rapid analysis of fluoxetine and its metabolite in plasma by LC-MS with column-switching approach. | Analytical and bioanalytical chemistry 20031101 |
| Maternal fluoxetine treatment in the postpartum period: effects on platelet serotonin and plasma drug levels in breastfeeding mother-infant pairs. | Pediatrics 20031101 |
| Comparative bioavailability of fluoxetine after transdermal and oral administration to healthy cats. | American journal of veterinary research 20030801 |
| Pharmacokinetics of fluoxetine and norfluoxetine in pregnancy and lactation. | Clinical pharmacology and therapeutics 20030401 |
| Fluoxetine increases GABA(A) receptor activity through a novel modulatory site. | The Journal of pharmacology and experimental therapeutics 20030301 |
| Improved enantioselective assay for the determination of fluoxetine and norfluoxetine enantiomers in human plasma by liquid chromatography. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030205 |
| [11C]-DASB, a tool for in vivo measurement of SSRI-induced occupancy of the serotonin transporter: PET characterization and evaluation in cats. | Synapse (New York, N.Y.) 20030201 |
| Direct stereoselective assay of fluoxetine and norfluoxetine enantiomers in human plasma or serum by two-dimensional gas-liquid chromatography with nitrogen-phosphorus selective detection. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030115 |
| Determination of fluoxetine and norfluoxetine in human plasma by high-performance liquid chromatography with ultraviolet detection in psychiatric patients. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030105 |
| Determination of fluoxetine and norfluoxetine in rat plasma by HPLC with pre-column derivatization and fluorescence detection. | Biomedical chromatography : BMC 20030101 |
| Fluoxetine pharmacokinetics in pediatric patients. | Journal of clinical psychopharmacology 20021201 |
| Simultaneous quantification of citalopram, clozapine, fluoxetine, norfluoxetine, maprotiline, desmethylmaprotiline and trazodone in human serum by HPLC analysis. | International journal of clinical pharmacology and therapeutics 20021201 |
| Kinetics of allopregnanolone formation catalyzed by human 3 alpha-hydroxysteroid dehydrogenase type III (AKR1C2). | Biochemistry 20021112 |
| Plasma concentrations of the enantiomers of fluoxetine and norfluoxetine: sources of variability and preliminary observations on relations with clinical response. | Therapeutic drug monitoring 20021001 |
| Estimates of nursing infant daily dose of fluoxetine through breast milk. | Biological psychiatry 20020901 |
| Transplacental transfer of citalopram, fluoxetine and their primary demethylated metabolites in isolated perfused human placenta. | BJOG : an international journal of obstetrics and gynaecology 20020901 |
| Micellar electrokinetic capillary chromatography for the determination of fluoxetine and its metabolite norfluoxetine in biological fluids. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020405 |
| Fluoxetine and norfluoxetine plasma concentrations during relapse-prevention treatment. | Journal of affective disorders 20020401 |
| Liquid chromatography/tandem mass spectrometry for the determination of fluoxetine and its main active metabolite norfluoxetine in human plasma with deuterated fluoxetine as internal standard. | Rapid communications in mass spectrometry : RCM 20020101 |
| Fluoxetine and norfluoxetine plasma levels after discontinuing fluoxetine therapy. | Journal of clinical psychopharmacology 20011201 |
| Fluoxetine and norfluoxetine concentrations in nursing infants and breast milk. | Biological psychiatry 20011115 |
| Effects of norfluoxetine, the major metabolite of fluoxetine, on the cloned neuronal potassium channel Kv3.1. | Neuropharmacology 20010901 |
| Effect of the CYP2C19 oxidation polymorphism on fluoxetine metabolism in Chinese healthy subjects. | British journal of clinical pharmacology 20010701 |
| Identification of the human cytochromes p450 responsible for in vitro formation of R- and S-norfluoxetine. | The Journal of pharmacology and experimental therapeutics 20010601 |
| Concentrations of the enantiomers of fluoxetine and norfluoxetine after multiple doses of fluoxetine in cytochrome P4502D6 poor and extensive metabolizers. | Journal of clinical psychopharmacology 20010601 |
| Sensitive liquid chromatographic-tandem mass spectrometric method for the determination of fluoxetine and its primary active metabolite norfluoxetine in human plasma. | Journal of chromatography. A 20010420 |
| Inhibition of phenytoin hydroxylation in human liver microsomes by several selective serotonin re-uptake inhibitors. | Epilepsy research 20010401 |
| Fluoxetine pharmacokinetics and effect on CYP2C19 in young and elderly volunteers. | Journal of clinical psychopharmacology 20010401 |
| Serum concentrations of fluoxetine in the clinical treatment setting. | Therapeutic drug monitoring 20010401 |
| Effect of venlafaxine versus fluoxetine on metabolism of dextromethorphan, a CYP2D6 probe. | Journal of clinical pharmacology 20010401 |
| Effect of alosetron on the pharmacokinetics of fluoxetine. | Journal of clinical pharmacology 20010401 |
| Effects of CYP2C19 genotype and CYP2C9 on fluoxetine N-demethylation in human liver microsomes. | Acta pharmacologica Sinica 20010101 |
| Determination of fluoxetine and norfluoxetine in human plasma by high-pressure liquid chromatography with fluorescence detection. | Journal of pharmaceutical and biomedical analysis 19981001 |
| Interactions of selective serotonin reuptake inhibitors with the serotonin 5-HT2c receptor. | Psychopharmacology 19960801 |
| Delirium during fluoxetine treatment. A case report. | Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 19931201 |