Home Other Building Blocks 2,2',4,6,6'-PENTACHLOROBIPHENYL

2,2',4,6,6'-PENTACHLOROBIPHENYL

CAS No.:
56558-16-8
Catalog Number:
AG00E8SM
Molecular Formula:
Molecular Weight:
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Product Description
Catalog Number:
AG00E8SM
Chemical Name:
2,2',4,6,6'-PENTACHLOROBIPHENYL
CAS Number:
56558-16-8
MDL Number:
MFCD00152717
IUPAC Name:
1,3,5-trichloro-2-(2,6-dichlorophenyl)benzene
InChI:
InChI=1S/C12H5Cl5/c13-6-4-9(16)12(10(17)5-6)11-7(14)2-1-3-8(11)15/h1-5H
InChI Key:
MTCPZNVSDFCBBE-UHFFFAOYSA-N
UNII:
Z4YYF101N3
Properties
Complexity:
237  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
325.88g/mol
Formal Charge:
0
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
0
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
326.422g/mol
Monoisotopic Mass:
323.883g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
0A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
5.8  
Literature
Title Journal
Polychlorinated biphenyl 104 promotes migration of endometrial stromal cells in endometriosis. Toxicology letters 20180615
In vitro toxicity profiling of ultrapure non-dioxin-like polychlorinated biphenyl congeners and their relative toxic contribution to PCB mixtures in humans. Toxicological sciences : an official journal of the Society of Toxicology 20110501
Polychlorinated biphenyls disrupt intestinal integrity via NADPH oxidase-induced alterations of tight junction protein expression. Environmental health perspectives 20100701
PCB-induced endothelial cell dysfunction: role of poly(ADP-ribose) polymerase. Biochemical pharmacology 20091015
Co-planar 3,3',4,4',5-pentachlorinated biphenyl and non-co-planar 2,2',4,6,6'-pentachlorinated biphenyl differentially induce recruitment of oestrogen receptor alpha to aryl hydrocarbon receptor target genes. The Biochemical journal 20070901
c-Src is the primary signaling mediator of polychlorinated biphenyl-induced interleukin-8 expression in a human microvascular endothelial cell line. Toxicological sciences : an official journal of the Society of Toxicology 20060701
Interplay between epidermal growth factor receptor and Janus kinase 3 regulates polychlorinated biphenyl-induced matrix metalloproteinase-3 expression and transendothelial migration of tumor cells. Molecular cancer research : MCR 20060601
2,2',4,6,6'-Pentachlorobiphenyl-induced apoptosis is limited by cyclooxygenase-2 induction. Toxicological sciences : an official journal of the Society of Toxicology 20050201
Fertility in four regions spanning large contrasts in serum levels of widespread persistent organochlorines: a cross-sectional study. Environmental health : a global access science source 20050101
VEGF regulates PCB 104-mediated stimulation of permeability and transmigration of breast cancer cells in human microvascular endothelial cells. Experimental cell research 20040610
2,2',4,6,6'-Pentachlorobiphenyl induces mitotic arrest and p53 activation. Toxicological sciences : an official journal of the Society of Toxicology 20040401
PCB 104-induced proinflammatory reactions in human vascular endothelial cells: relationship to cancer metastasis and atherogenesis. Toxicological sciences : an official journal of the Society of Toxicology 20030901
2,2',4,6,6'-pentachlorobiphenyl (PCB 104) induces apoptosis of human microvascular endothelial cells through the caspase-dependent activation of CREB. Toxicology and applied pharmacology 20030515
2,2',4,6,6'-pentachlorobiphenyl induces apoptosis in human monocytic cells. Toxicology and applied pharmacology 20001115
Properties