VIGABATRIN
| Title | Journal |
|---|---|
| Vigabatrin-induced CNS changes in juvenile rats: Induction, progression and recovery of myelin-related changes. | Neurotoxicology 20150101 |
| Valproate-related erythrodermia with reversible encephalopathy: a rare but serious adverse reaction, case report. | Acta dermatovenerologica Alpina, Pannonica, et Adriatica 20140101 |
| Evolution of visual field loss over ten years in individuals taking vigabatrin. | Epilepsy research 20130801 |
| Detection of 22 antiepileptic drugs by ultra-performance liquid chromatography coupled with tandem mass spectrometry applicable to routine therapeutic drug monitoring. | Biomedical chromatography : BMC 20121201 |
| Taurine deficiency damages retinal neurones: cone photoreceptors and retinal ganglion cells. | Amino acids 20121101 |
| Ohtahara syndrome or early-onset West syndrome? A case with overlapping features and favorable response to vigabatrin. | European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20121101 |
| Vigabatrin-associated retinal damage: potential biochemical mechanisms. | Acta neurologica Scandinavica 20121001 |
| Sildenafil influences the anticonvulsant activity of vigabatrin and gabapentin in the timed pentylenetetrazole infusion test in mice. | Progress in neuro-psychopharmacology & biological psychiatry 20121001 |
| Patterns of peripapillary retinal nerve fiber layer thinning in vigabatrin-exposed individuals. | Ophthalmology 20121001 |
| The current evaluation and treatment of infantile spasms among members of the Child Neurology Society. | Journal of child neurology 20121001 |
| Synthesis and evaluation of novel heteroaromatic substrates of GABA aminotransferase. | Bioorganic & medicinal chemistry 20121001 |
| A randomized controlled trial of flunarizine as add-on therapy and effect on cognitive outcome in children with infantile spasms. | Epilepsia 20120901 |
| T2 hyperintense signal of the central tegmental tracts in children: disease or normal maturational process? | Neuroradiology 20120801 |
| Coexisting seizures in patients with infantile spasms confirmed by long-term video-electroencephalography monitoring. | Epilepsy research 20120801 |
| Infantile spasms: treatment challenges. | Current treatment options in neurology 20120801 |
| Visual field and ocular safety during short-term vigabatrin treatment in cocaine abusers. | American journal of ophthalmology 20120801 |
| Effect of second-generation antiepileptic drugs on diplopia: a meta-analysis of placebo-controlled studies. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20120801 |
| Chemical properties of antiepileptic drugs (AEDs). | Advanced drug delivery reviews 20120701 |
| Evidence-based guideline update: medical treatment of infantile spasms. Report of the Guideline Development Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society. | Neurology 20120612 |
| Taurine-like GABA aminotransferase inhibitors prevent rabbit brain slices against oxygen-glucose deprivation-induced damage. | Amino acids 20120601 |
| Electroretinographic (ERG) responses in pediatric patients using vigabatrin. | Documenta ophthalmologica. Advances in ophthalmology 20120601 |
| Carrier-mediated γ-aminobutyric acid transport across the basolateral membrane of human intestinal Caco-2 cell monolayers. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120601 |
| [Anaesthesia of epileptic patient]. | Annales francaises d'anesthesie et de reanimation 20120601 |
| Rash in psychiatric and nonpsychiatric adolescent patients receiving lamotrigine in Korea: a retrospective cohort study. | Psychiatry investigation 20120601 |
| May GABA transaminase inhibitors improve stereotyped behaviors in Rett syndrome? | Amino acids 20120501 |
| Vigabatrin for focal drug delivery in epilepsy: bilateral microinfusion into the subthalamic nucleus is more effective than intranigral or systemic administration in a rat seizure model. | Neurobiology of disease 20120501 |
| Vigabatrin-induced forced normalization and psychosis--prolongated termination of behavioral symptoms but persistent antiepileptic effect after withdrawal. | Epilepsy & behavior : E&B 20120501 |
| Outcomes of epileptic spasms in patients aged less than 3 years: single-center United States experience. | Pediatric neurology 20120501 |
| Acute and subchronic toxicological evaluation of Echinophora platyloba DC (Apiaceae) total extract in Wistar rats. | Clinics (Sao Paulo, Brazil) 20120501 |
| Rectal absorption of vigabatrin, a substrate of the proton coupled amino acid transporter (PAT1, Slc36a1), in rats. | Pharmaceutical research 20120401 |
| Effects of vigabatrin, an irreversible GABA transaminase inhibitor, on ethanol reinforcement and ethanol discriminative stimuli in mice. | Behavioural pharmacology 20120401 |
| Beneficial and adverse psychotropic effects of antiepileptic drugs in patients with epilepsy: a summary of prevalence, underlying mechanisms and data limitations. | CNS drugs 20120401 |
| [Pharmacological treatment of spasticity in multiple sclerosis]. | Revue neurologique 20120401 |
| Vigabatrin monotherapy for infantile spasms. | Expert review of neurotherapeutics 20120301 |
| Prevalence of treated epilepsy in Korea based on national health insurance data. | Journal of Korean medical science 20120301 |
| Interactions of pregabalin with gabapentin, levetiracetam, tiagabine and vigabatrin in the mouse maximal electroshock-induced seizure model: a type II isobolographic analysis. | Epilepsy research 20120201 |
| Retinal and cochlear toxicity of drugs: new insights into mechanisms and detection. | Current opinion in neurology 20120201 |
| [Enriched-enrollment randomized-withdrawal trials]. | Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20120201 |
| Vigabatrin for childhood partial-onset epilepsies. | Pediatric neurology 20120201 |
| Historic, clinical, and prognostic features of epileptic encephalopathies caused by CDKL5 mutations. | Pediatric neurology 20120201 |
| The 2011 E. B. Hershberg award for important discoveries in medicinally active substances: (1S,3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115), a GABA aminotransferase inactivator and new treatment for drug addiction and infantile spasms. | Journal of medicinal chemistry 20120126 |
| Vigabatrin versus carbamazepine monotherapy for epilepsy. | The Cochrane database of systematic reviews 20120118 |
| (1S, 3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115), a potent γ-aminobutyric acid aminotransferase inactivator for the treatment of cocaine addiction. | Journal of medicinal chemistry 20120112 |
| Clavulanic acid does not affect convulsions in acute seizure tests in mice. | Journal of neural transmission (Vienna, Austria : 1996) 20120101 |
| Use of the modified Atkins diet in infantile spasms refractory to first-line treatment. | Seizure 20120101 |
| Mitochondrial toxicity of antiepileptic drugs and their tolerability in mitochondrial disorders. | Expert opinion on drug metabolism & toxicology 20120101 |
| GABA expression and regulation by sensory experience in the developing visual system. | PloS one 20120101 |
| Weight-reducing side effects of the antiepileptic agents topiramate and zonisamide. | Handbook of experimental pharmacology 20120101 |
| Parallel mapping and simultaneous sequencing reveals deletions in BCAN and FAM83H associated with discrete inherited disorders in a domestic dog breed. | PLoS genetics 20120101 |
| Topiramate and the vision: a systematic review. | Clinical ophthalmology (Auckland, N.Z.) 20120101 |
| Clinical utility of adjunctive retigabine in partial onset seizures in adults. | Therapeutics and clinical risk management 20120101 |
| GABA Not Only a Neurotransmitter: Osmotic Regulation by GABA(A)R Signaling. | Frontiers in cellular neuroscience 20120101 |
| A microdialysis study of oral vigabatrin administration in head injury patients: preliminary evaluation of multimodality monitoring. | Acta neurochirurgica. Supplement 20120101 |
| Forty-year-old diabetic lady with tightness in lower limbs. | Annals of Indian Academy of Neurology 20120101 |
| [Pregabalin--a drug with abuse potential?]. | Archiv fur Kriminologie 20120101 |
| Epilepsy as a neurodevelopmental disorder. | Frontiers in psychiatry 20120101 |
| Zimelidine attenuates the development of tolerance to morphine-induced antinociception. | Indian journal of pharmacology 20120101 |
| GABA metabolism and transport: effects on synaptic efficacy. | Neural plasticity 20120101 |
| Acute and 28-Day Subchronic Oral Toxicity of an Ethanol Extract of Zingiber zerumbet (L.) Smith in Rodents. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
| Salicylate toxicity model of tinnitus. | Frontiers in systems neuroscience 20120101 |
| Effects of vigabatrin on the skeletal system of young rats. | Acta poloniae pharmaceutica 20120101 |
| Pharmacological management of binge eating disorder: current and emerging treatment options. | Therapeutics and clinical risk management 20120101 |
| Vigabatrin-associated visual field loss. | International ophthalmology clinics 20120101 |
| Infantile spasms (West syndrome): update and resources for pediatricians and providers to share with parents. | BMC pediatrics 20120101 |
| Vigabatrin-induced retinal toxicity is partially mediated by signaling in rod and cone photoreceptors. | PloS one 20120101 |
| [The course and treatment of epilepsy in children with tuberose sclerosis]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20120101 |
| New developments in the treatment of partial-onset epilepsy. | Neuropsychiatric disease and treatment 20120101 |
| A systematic review of the pharmacokinetics of antiepileptic drugs in neonates with refractory seizures. | The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG 20120101 |
| Review of therapeutic options for adjuvant treatment of focal seizures in epilepsy: focus on lacosamide. | CNS drugs 20111205 |
| Oral toxicity of vigabatrin in immature rats: characterization of intramyelinic edema. | Neurotoxicology 20111201 |
| The SLC36 family of proton-coupled amino acid transporters and their potential role in drug transport. | British journal of pharmacology 20111201 |
| Activity-dependent γ-aminobutyric acid release controls brain cortical tissue slice metabolism. | Journal of neuroscience research 20111201 |
| Early age conductive hearing loss causes audiogenic seizure and hyperacusis behavior. | Hearing research 20111201 |
| Transition to absence seizures and the role of GABA(A) receptors. | Epilepsy research 20111201 |
| Registry initiated to characterize vision loss associated with vigabatrin therapy. | Epilepsy & behavior : E&B 20111201 |
| Long-term neurological outcome in children with early-onset epilepsy associated with tuberous sclerosis. | Epilepsy & behavior : E&B 20111201 |
| Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). | PLoS computational biology 20111201 |
| Clinical progress of epilepsy in children with tuberous sclerosis: prognostic factors for seizure outcome. | Chonnam medical journal 20111201 |
| Experimental panic provocation in healthy man-a translational role in anti-panic drug development? | Dialogues in clinical neuroscience 20111201 |
| Treatment of West syndrome with vigabatrin: reversible MRI signal changes. | Arquivos de neuro-psiquiatria 20111201 |
| Enhanced GABAergic tone in the ventral pallidum: memory of unpleasant experiences? | Neuroscience 20111124 |
| Vigabatrin has antiepileptogenic and antidepressant effects in an animal model of epilepsy and depression comorbidity. | Behavioural brain research 20111120 |
| Mechanisms of GABA release from human astrocytes. | Glia 20111101 |
| Medication neurotoxicity in children. | Pediatric radiology 20111101 |
| Screening for vigabatrin (Sabril ®) retinal toxicity in children. | Ophthalmic genetics 20111101 |
| Fundal changes in children receiving Vigabatrin. | Indian journal of pediatrics 20111001 |
| Dravet syndrome as epileptic encephalopathy: evidence from long-term course and neuropathology. | Brain : a journal of neurology 20111001 |
| Sensitivity and specificity of retinal nerve fiber layer thinning to detect visual field loss from vigabatrin. | Annals of neurology 20111001 |
| Measuring field loss in children administered vigabatrin: a problem in search of a solution. | Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus 20111001 |
| Modelling the topography of absolute defects in patients exposed to the anti-epileptic drug vigabatrin and in normal subjects using automated static suprathreshold perimetry of the entire 80° visual field. | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20110901 |
| Carisbamate acutely suppresses spasms in a rat model of symptomatic infantile spasms. | Epilepsia 20110901 |
| [Aicardi syndrome associated with severe congenital ptosis]. | Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20110901 |
| Validation of the rat model of cryptogenic infantile spasms. | Epilepsia 20110901 |
| Angelman syndrome and pseudo-hypsarrhythmia: a diagnostic pitfall. | Epileptic disorders : international epilepsy journal with videotape 20110901 |
| Psychiatric symptoms and quality of life in patients with drug-refractory epilepsy receiving adjunctive levetiracetam therapy. | Journal of clinical neurology (Seoul, Korea) 20110901 |
| Short term outcomes of topiramate monotherapy as a first-line treatment in newly diagnosed West syndrome. | Korean journal of pediatrics 20110901 |
| GABAergic neural activity involved in salicylate-induced auditory cortex gain enhancement. | Neuroscience 20110825 |
| Retinal nerve fibre layer attenuation: clinical indicator for vigabatrin toxicity. | Acta ophthalmologica 20110801 |
| Treatment options in juvenile myoclonic epilepsy. | Current treatment options in neurology 20110801 |
| A pulse rapamycin therapy for infantile spasms and associated cognitive decline. | Neurobiology of disease 20110801 |
| Antiepileptic drug discovery: does mechanism of action matter? | Epilepsy & behavior : E&B 20110801 |
| Gabapentin: An update of its pharmacological properties and therapeutic use in epilepsy. | Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences 20110801 |
| Gender-specific effect of Mthfr genotype and neonatal vigabatrin interaction on synaptic proteins in mouse cortex. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20110701 |
| The effect of lead time to treatment and of age of onset on developmental outcome at 4 years in infantile spasms: evidence from the United Kingdom Infantile Spasms Study. | Epilepsia 20110701 |
| Neuronal mechanisms underlying development of nicotine dependence: implications for novel smoking-cessation treatments. | Addiction science & clinical practice 20110701 |
| Inhalant use and inhalant use disorders in the United States. | Addiction science & clinical practice 20110701 |
| Is anticonvulsant treatment of mania a class effect? Data from randomized clinical trials. | CNS neuroscience & therapeutics 20110601 |
| Electroretinogram changes in a pediatric population with epilepsy: is vigabatrin acting alone? | Journal of child neurology 20110601 |
| Paediatric post-marketing pharmacovigilance: comparison of the adverse event profile of vigabatrin prescribed to children and adults. | Pharmacoepidemiology and drug safety 20110601 |
| Diagnosis and management of glutaric aciduria type I--revised recommendations. | Journal of inherited metabolic disease 20110601 |
| Clinical and Rehabilitative Management of Retinitis Pigmentosa: Up-to-Date. | Current genomics 20110601 |
| Precolumn derivatization followed by liquid chromatographic separation and determination of tramiprosate in rat plasma by fluorescence detector: application to pharmacokinetics. | Journal of pharmaceutical and biomedical analysis 20110515 |
| Effects of GABA-transaminase inhibitor Vigabatrin on thermoregulation in rats. | Amino acids 20110501 |
| Reversible magnetic resonance imaging and spectroscopy abnormalities in the course of vigabatrin treatment for West syndrome. | European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20110501 |
| Retinal nerve fiber layer thickness in vigabatrin-exposed patients. | Annals of neurology 20110501 |
| Magnetic resonance spectroscopy studies of human metabolism. | Diabetes 20110501 |
| Antiepileptic drugs and the immune system. | Epilepsia 20110501 |
| Drug resistance in epilepsy and the ABCB1 gene: The clinical perspective. | Indian journal of human genetics 20110501 |
| Seizure outcome in infantile spasms--a retrospective study. | Epilepsia 20110401 |
| Epilepsy: Vigabatrin treatment and visual field loss. | Nature reviews. Neurology 20110401 |
| Non-neuronal, slow GABA signalling in the ventrobasal thalamus targets δ-subunit-containing GABA(A) receptors. | The European journal of neuroscience 20110401 |
| A substituted anilino enaminone acts as a novel positive allosteric modulator of GABA(A) receptors in the mouse brain. | The Journal of pharmacology and experimental therapeutics 20110301 |
| Vigabatrin for infantile spasms. | Pharmacotherapy 20110301 |
| Depressogenic effects of medications: a review. | Dialogues in clinical neuroscience 20110301 |
| Gaboxadol has affinity for the proton-coupled amino acid transporter 1, SLC36A1 (hPAT1)--A modelling approach to determine IC(50) values of the three ionic species of gaboxadol. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20110214 |
| Knockout of GAD65 has major impact on synaptic GABA synthesized from astrocyte-derived glutamine. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20110201 |
| Successful transfer to sulfonylurea therapy in an infant with developmental delay, epilepsy and neonatal diabetes (DEND) syndrome and a novel ABCC8 gene mutation. | Diabetologia 20110201 |
| Anesthetic experience of a patient with Ohtahara syndrome -A case report-. | Korean journal of anesthesiology 20110201 |
| An historical perspective on GABAergic drugs. | Future medicinal chemistry 20110201 |
| Sex-dependent behavioral effects of Mthfr deficiency and neonatal GABA potentiation in mice. | Behavioural brain research 20110120 |
| [West syndrome: aetiology, therapeutic options, clinical course and prognostic factors]. | Revista de neurologia 20110116 |
| Abnormal axial diffusivity in the deep gray nuclei and dorsal brain stem in infantile spasm treated with vigabatrin. | AJNR. American journal of neuroradiology 20110101 |
| Astrocytes are GABAergic cells that modulate microglial activity. | Glia 20110101 |
| Mutations and deletions in PCDH19 account for various familial or isolated epilepsies in females. | Human mutation 20110101 |
| Association of antiepileptic drugs with nontraumatic fractures: a population-based analysis. | Archives of neurology 20110101 |
| Electrophysiological evaluation of retinal function in children receiving vigabatrin medication. | Journal of pediatric ophthalmology and strabismus 20110101 |
| Visual fields in neuro-ophthalmology. | Indian journal of ophthalmology 20110101 |
| [Compassionate use of vigabatrin for intractable epilepsy in Japan]. | No to hattatsu = Brain and development 20110101 |
| Transcriptomic analysis in a Drosophila model identifies previously implicated and novel pathways in the therapeutic mechanism in neuropsychiatric disorders. | Frontiers in neuroscience 20110101 |
| Epilepsy (partial). | BMJ clinical evidence 20110101 |
| 4-aminobutyrate aminotransferase (ABAT): genetic and pharmacological evidence for an involvement in gastro esophageal reflux disease. | PloS one 20110101 |
| Traditional and non-traditional treatments for autism spectrum disorder with seizures: an on-line survey. | BMC pediatrics 20110101 |
| Management of provoked seizure. | Annals of Indian Academy of Neurology 20110101 |
| Utility of certain nucleophilic aromatic substitution reactions for the assay of pregabalin in capsules. | Chemistry Central journal 20110101 |
| The effect of gabapentin on gap detection and forward masking in young and old gerbils. | Ear and hearing 20110101 |
| Suicidal behavior and antiepileptic drugs in epilepsy: analysis of the emerging evidence. | Drug, healthcare and patient safety 20110101 |
| Sensitive and selective spectrophotometric determination of gabapentin in capsules using two nitrophenols as chromogenic agents. | International journal of analytical chemistry 20110101 |
| Clinical uses of melatonin in pediatrics. | International journal of pediatrics 20110101 |
| Evaluation of Heart Rate Variation Analysis during Rest and Tilting in Patients with Temporal Lobe Epilepsy. | Neurology research international 20110101 |
| An integrative view of mechanisms underlying generalized spike-and-wave epileptic seizures and its implication on optimal therapeutic treatments. | PloS one 20110101 |
| Altered GABA signaling in early life epilepsies. | Neural plasticity 20110101 |
| Augmentation of Tonic GABA(A) Inhibition in Absence Epilepsy: Therapeutic Value of Inverse Agonists at Extrasynaptic GABA(A) Receptors. | Advances in pharmacological sciences 20110101 |
| Treatment options for refractory and difficult to treat seizures: focus on vigabatrin. | Therapeutics and clinical risk management 20110101 |
| Lamotrigine-induced SIADH in a child with central diabetes insipidus. | Journal of pediatric neurosciences 20110101 |
| A novel method for spectrophotometric determination of pregabalin in pure form and in capsules. | Chemistry Central journal 20110101 |
| Phenytoin-induced gingival overgrowth: a review of the molecular, immune, and inflammatory features. | ISRN dentistry 20110101 |
| Prenatal VPA Exposure and Changes in Sensory Processing by the Superior Colliculus. | Frontiers in integrative neuroscience 20110101 |
| Severe myoclonic epilepsy of infancy (Dravet syndrome): Clinical and genetic features of nine Turkish patients. | Annals of Indian Academy of Neurology 20110101 |
| Novel pharmacotherapeutic treatments for cocaine addiction. | BMC medicine 20110101 |
| Vigabatrin 35 years later - from mechanism of action to benefit-risk considerations. | Acta neurologica Scandinavica. Supplementum 20110101 |
| Mechanism of action of vigabatrin: correcting misperceptions. | Acta neurologica Scandinavica. Supplementum 20110101 |
| Vigabatrin therapy for refractory complex partial seizures: review of major European trials. | Acta neurologica Scandinavica. Supplementum 20110101 |
| Vigabatrin therapy for refractory complex partial seizures: review of clinical trial experience in the United States. | Acta neurologica Scandinavica. Supplementum 20110101 |
| Vigabatrin therapy for infantile spasms: review of major trials in Europe, Canada, and the United States; and recommendations for dosing. | Acta neurologica Scandinavica. Supplementum 20110101 |
| Primer on visual field testing, electroretinography, and other visual assessments for patients treated with vigabatrin. | Acta neurologica Scandinavica. Supplementum 20110101 |
| Understanding and interpreting vision safety issues with vigabatrin therapy. | Acta neurologica Scandinavica. Supplementum 20110101 |
| Non-vision adverse events with vigabatrin therapy. | Acta neurologica Scandinavica. Supplementum 20110101 |
| Balancing clinical benefits of vigabatrin with its associated risk of vision loss. | Acta neurologica Scandinavica. Supplementum 20110101 |
| Effect of Gentiana olivieri on experimental epilepsy models. | Pharmacognosy magazine 20110101 |
| Progressive encephalopathy with edema, hypsarrhythmia, and optic atrophy and PEHO-like syndrome: Report of two cases. | Journal of pediatric neurosciences 20110101 |
| MRI changes associated with vigabatrin treatment mimicking tumor progression. | Pediatric blood & cancer 20101201 |
| Vigabatrin-associated diffusion MRI abnormalities in tuberous sclerosis. | Pediatric radiology 20101201 |
| Comparative anticonvulsant efficacy in the corneal kindled mouse model of partial epilepsy: Correlation with other seizure and epilepsy models. | Epilepsy research 20101201 |
| Vigabatrin-induced peripheral visual field defects in patients with refractory partial epilepsy. | Epilepsy research 20101201 |
| Prevalence of visual field loss following exposure to vigabatrin therapy: a systematic review. | Epilepsia 20101201 |
| New drugs for pediatric epilepsy. | Seminars in pediatric neurology 20101201 |
| Use of antiepileptic drugs for hyperkinetic movement disorders. | Current neuropharmacology 20101201 |
| 'Epileptic encephalopathy' of infancy and childhood: electro-clinical pictures and recent understandings. | Current neuropharmacology 20101201 |
| [Epileptic spasms without hypsarrhythmia. A new case report and review of the literature]. | Revista de neurologia 20101116 |
| Vigabatrin for the treatment of infantile spasms: final report of a randomized trial. | Journal of child neurology 20101101 |
| Recommendations for visual evaluations of patients treated with vigabatrin. | Current opinion in ophthalmology 20101101 |
| Is reduced ornithine-δ-aminotransferase activity the cause of vigabatrin-associated visual field defects? | Epilepsy research 20101101 |
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
| Vigabatrin administration in patients with infantile spasms: the risks. | Clinical neurology and neurosurgery 20101101 |
| Assessing the unmet treatment need in partial-onset epilepsy: looking beyond seizure control. | Epilepsia 20101101 |
| [Effectiveness of vigabatrin in west syndrome associated with tuberous sclerosis]. | No to hattatsu = Brain and development 20101101 |
| Infantile spasms: a U.S. consensus report. | Epilepsia 20101001 |
| γ-Hydroxybutyrate and the GABAergic footprint: a metabolomic approach to unpicking the actions of GHB. | Journal of neurochemistry 20101001 |
| Infantile spasms: toward a selective diagnostic and therapeutic approach. | Epilepsia 20101001 |
| The Japanese scheme of ACTH therapy in West syndrome. | Epilepsia 20101001 |
| The proton-coupled amino acid transporter, SLC36A1 (hPAT1), transports Gly-Gly, Gly-Sar and other Gly-Gly mimetics. | British journal of pharmacology 20101001 |
| A European perspective—comments on 'Infantile spasms: a U.S. consensus report'. | Epilepsia 20101001 |
| Simultaneous HPLC-F analysis of three recent antiepileptic drugs in human plasma. | Journal of pharmaceutical and biomedical analysis 20100921 |
| Early infantile epileptic encephalopathy with unusual favourable outcome. | Brain & development 20100901 |
| Region-specific changes in gene expression in rat brain after chronic treatment with levetiracetam or phenytoin. | Epilepsia 20100901 |
| Maternal uniparental isodisomy is responsible for serious molybdenum cofactor deficiency. | Developmental medicine and child neurology 20100901 |
| Coexistence of cerebral tubers with neurocysticercosis. | Southern medical journal 20100901 |
| Drug off-target effects predicted using structural analysis in the context of a metabolic network model. | PLoS computational biology 20100901 |
| Antiepileptic drug interactions - principles and clinical implications. | Current neuropharmacology 20100901 |
| A high-performance liquid chromatography assay to monitor the new antiepileptic drug lacosamide in patients with epilepsy. | Therapeutic drug monitoring 20100801 |
| Infantile spasms treated with the ketogenic diet: prospective single-center experience in 104 consecutive infants. | Epilepsia 20100801 |
| Use of antiepileptic drugs in epilepsy and the risk of self-harm or suicidal behavior. | Neurology 20100727 |
| ACS chemical neuroscience molecule spotlight on Sabril. | ACS chemical neuroscience 20100721 |
| Vigabatrin: an antiepileptic drug with major benefits but significant adverse effects. | Current drug safety 20100702 |
| Vigabatrin-associated reversible MRI signal changes in patients with infantile spasms. | Epilepsia 20100701 |
| Update on anticonvulsant drugs. | Current neurology and neuroscience reports 20100701 |
| Modeling new therapies for infantile spasms. | Epilepsia 20100701 |
| Visual fields in children exposed to vigabatrin in infancy. | Epilepsia 20100701 |
| Can we change the course of epilepsy in tuberous sclerosis complex? | Epilepsia 20100701 |
| New antiepileptic drugs: lacosamide, rufinamide, and vigabatrin. | Current treatment options in neurology 20100701 |
| Epilepsy (partial). | BMJ clinical evidence 20100628 |
| Vigabatrin (VGB) administered during late gestation lowers maternal folate concentration and causes pregnancy loss, fetal growth restriction and skeletal hypoplasia in the mouse. | Reproductive toxicology (Elmsford, N.Y.) 20100601 |
| Predictors of suicidal ideation in people with epilepsy living in Korea. | Journal of clinical neurology (Seoul, Korea) 20100601 |
| Meta-regression with partial information on summary trial or patient characteristics. | Statistics in medicine 20100530 |
| Placebo effects in neurological diseases. | Journal of medicine and life 20100515 |
| Renal stone associated with the ketogenic diet in a 5-year old girl with intractable epilepsy. | Yonsei medical journal 20100501 |
| [Antiepileptic drugs in North America]. | Brain and nerve = Shinkei kenkyu no shinpo 20100501 |
| Developmental and epilepsy outcomes at age 4 years in the UKISS trial comparing hormonal treatments to vigabatrin for infantile spasms: a multi-centre randomised trial. | Archives of disease in childhood 20100501 |
| A sensitive period of mice inhibitory system to neonatal GABA enhancement by vigabatrin is brain region dependent. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100401 |
| Therapy of infantile spasms: new opportunities and emerging challenges. | Epilepsy & behavior : E&B 20100401 |
| Taurine deficiency damages photoreceptors and retinal ganglion cells in vigabatrin-treated neonatal rats. | Molecular and cellular neurosciences 20100401 |
| Treatment and long term outcome in West syndrome: the clinical reality. A multicentre follow up study. | Seizure 20100401 |
| Early control of seizures improves long-term outcome in children with tuberous sclerosis complex. | European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20100301 |
| Vigabatrin but not valproate prevents development of age-specific flexion seizures induced by N-methyl-D-aspartate (NMDA) in immature rats. | Epilepsia 20100301 |
| A model of symptomatic infantile spasms syndrome. | Neurobiology of disease 20100301 |
| Gamma-vinyl GABA increases nonvesicular release of GABA and glutamate in the nucleus accumbens in rats via action on anion channels and GABA transporters. | Psychopharmacology 20100301 |
| Infantile spasms. | The neurologist 20100301 |
| Vigabatrin (Sabril) for epilepsy. | The Medical letter on drugs and therapeutics 20100222 |
| [Succinic semialdehyde dehydrogenase deficiency: decrease in 4-OH-butyric acid levels with low doses of vigabatrin]. | Anales de pediatria (Barcelona, Spain : 2003) 20100201 |
| A new case of GABA transaminase deficiency facilitated by proton MR spectroscopy. | Journal of inherited metabolic disease 20100201 |
| Behavioral and cognitive effects of anti-epileptic drugs. | Discovery medicine 20100201 |
| Effects of poly-gamma-glutamic acid on serum and brain concentrations of glutamate and GABA in diet-induced obese rats. | Nutrition research and practice 20100201 |
| Infantile spasms: who are the ideal surgical candidates? | Epilepsia 20100201 |
| Favourable prognostic factors with infantile spasms. | European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20100101 |
| Delayed, rapid visual field loss in a patient after ten years of vigabatrin therapy. | Eye (London, England) 20100101 |
| Management of West syndrome in a patient with methylmalonic aciduria. | Journal of child neurology 20100101 |
| Drug interactions involving the new second- and third-generation antiepileptic drugs. | Expert review of neurotherapeutics 20100101 |
| Role of antiepileptic drugs as preventive agents for migraine. | CNS drugs 20100101 |
| Clinical profile and treatment of infantile spasms using vigabatrin and ACTH--a developing country perspective. | BMC pediatrics 20100101 |
| Detecting retinal vigabatrin toxicity in patients with partial symptomatic or cryptogenic epilepsy. | European journal of ophthalmology 20100101 |
| [Therapeutic drug monitoring of vigabatrin]. | Therapie 20100101 |
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| [Asymptomatic concentric visual field deficits and optic nerve atrophy]. | Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20060601 |
| Tiagabine and vigabatrin reduce the severity of NMDA-induced excitotoxicity in chick retina. | Experimental brain research 20060601 |
| Cryptogenic late-onset epileptic spasms: an overlooked syndrome of early childhood? | Epilepsia 20060601 |
| Limited P-glycoprotein mediated efflux for anti-epileptic drugs. | Journal of drug targeting 20060601 |
| Inhibition of rabbit brain 4-aminobutyrate transaminase by some taurine analogues: a kinetic analysis. | Biochemical pharmacology 20060514 |
| Absence and myoclonic status epilepticus precipitated by antiepileptic drugs in idiopathic generalized epilepsy. | Brain : a journal of neurology 20060501 |
| Pharmacotherapy for alcohol dependence: anticraving medications for relapse prevention. | Yonsei medical journal 20060430 |
| Starting and stopping mechanisms of absence epileptic seizures are revealed by hazard functions. | Journal of neuroscience methods 20060415 |
| Capillary electrophoresis enantioselective separation of vigabatrin enantiomers by precolumn derivatization with dehydroabietylisothiocyante and UV-vis detection. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060403 |
| [Treatment of infantile spasms]. | Ugeskrift for laeger 20060403 |
| Current management for epilepsy in tuberous sclerosis complex. | Current opinion in neurology 20060401 |
| Evidence that GAD65 mediates increased GABA synthesis during intense neuronal activity in vivo. | Journal of neurochemistry 20060401 |
| Synthesis of functionalized pyrrolidin-2-ones and (S)-Vigabatrin from pyrrole. | The Journal of organic chemistry 20060303 |
| Glucose inhibits GABA release by pancreatic beta-cells through an increase in GABA shunt activity. | American journal of physiology. Endocrinology and metabolism 20060301 |
| New substrates and inhibitors of gamma-aminobutyric acid aminotransferase containing bioisosteres of the carboxylic acid group: design, synthesis, and biological activity. | Bioorganic & medicinal chemistry 20060301 |
| Detecting vigabatrin toxicity by imaging of the retinal nerve fiber layer. | Investigative ophthalmology & visual science 20060301 |
| Aicardi syndrome: a report of five Indian cases. | Neurology India 20060301 |
| Vigabatrin transport across the human intestinal epithelial (Caco-2) brush-border membrane is via the H+ -coupled amino-acid transporter hPAT1. | British journal of pharmacology 20060201 |
| Vigabatrin retinopathy in an Irish cohort: lack of correlation with dose. | Epilepsia 20060201 |
| Reduced calcium binding protein immunoreactivity induced by electroconvulsive shock indicates neuronal hyperactivity, not neuronal death or deactivation. | Neuroscience 20060101 |
| Interactions between antiepileptic and antipsychotic drugs. | Drug safety 20060101 |
| Demonstration of extensive GABA synthesis in the small population of GAD positive neurons in cerebellar cultures by the use of pharmacological tools. | Neurochemistry international 20060101 |
| Acute regulation of steady-state GABA levels following GABA-transaminase inhibition in rat cerebral cortex. | Neurochemistry international 20060101 |
| Vigabatrin caused rapidly progressive deterioration in two cases with early myoclonic encephalopathy associated with nonketotic hyperglycinemia. | Journal of child neurology 20060101 |
| Vigabatrin in pediatric patients with refractory epilepsy. | The Turkish journal of pediatrics 20060101 |
| Clinical pharmacokinetics of new-generation antiepileptic drugs at the extremes of age. | Clinical pharmacokinetics 20060101 |
| Retinal function in rabbits does not improve 4-5 months after terminating treatment with vigabatrin. | Documenta ophthalmologica. Advances in ophthalmology 20060101 |
| A plausible explanation for superiority of adreno-cortico-trophic hormone (ACTH) over oral corticosteroids in management of infantile spasms (West syndrome). | Medical hypotheses 20060101 |
| Glial modulation of GABAergic and glutamat ergic neurotransmission. | Current topics in medicinal chemistry 20060101 |
| Pharmacokinetic variability of newer antiepileptic drugs: when is monitoring needed? | Clinical pharmacokinetics 20060101 |
| Pragmatic difficulties in children with autism associated with childhood epilepsy. | Pediatric rehabilitation 20060101 |
| Prolonged nicotine exposure does not alter GABA(B) receptor-mediated regulation of brain reward function. | Neuropharmacology 20051201 |
| [Infantile spasms as the first manifestation of propionic acidemia]. | Anales de pediatria (Barcelona, Spain : 2003) 20051201 |
| Pharmacokinetic variability of new antiepileptic drugs at different ages. | Therapeutic drug monitoring 20051201 |
| Valproic acid reduces enhanced vesicular glutamate transporter immunoreactivities in the dentate gyrus of the seizure prone gerbil. | Neuropharmacology 20051101 |
| The United Kingdom Infantile Spasms Study (UKISS) comparing hormone treatment with vigabatrin on developmental and epilepsy outcomes to age 14 months: a multicentre randomised trial. | The Lancet. Neurology 20051101 |
| Visual defects associated with vigabatrin: a study of epileptic argentine patients. | The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20051101 |
| Induction of endogenous pathways by antiepileptics and clinical implications. | Fundamental & clinical pharmacology 20051001 |
| Differential effects of vigabatrin and zonisamide on the neuropeptide Y system in the hippocampus of seizure prone gerbil. | Neuropeptides 20051001 |
| Visual function in epilepsy patients treated with initial valproate monotherapy. | Seizure 20050901 |
| Effect of neurosteroids on the retinal gabaergic system and electroretinographic activity in the golden hamster. | Journal of neurochemistry 20050901 |
| Preclinical profiling and safety studies of ABT-769: a compound with potential for broad-spectrum antiepileptic activity. | Epilepsia 20050901 |
| Towards a synthesis of vigabatrin using glycal chemistry. | Molecules (Basel, Switzerland) 20050831 |
| [Infantile spasms]. | Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20050825 |
| [Infantile spasms]. | Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20050811 |
| Application of capillary zone electrophoresis with indirect UV detection to the determination of a model drug, vigabatrin, in dosage forms. | Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20050803 |
| Ocular complications of neurological therapy. | European journal of neurology 20050701 |
| Vigabatrin toxicity in children. | Ophthalmology 20050701 |
| Ophthalmologic and neurologic findings in two children exposed to vigabatrin in utero. | Epilepsy research 20050601 |
| Vigabatrin in low doses selectively suppresses the clonic component of audiogenically kindled seizures in rats. | Epilepsia 20050601 |
| Maternal exposure to the antiepileptic drug vigabatrin affects postnatal development in the rat. | Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20050601 |
| [Efficacy and tolerability of vigabatrin in West syndrome]. | Arquivos de neuro-psiquiatria 20050601 |
| Cross Hypersensitivity Syndrome between Phenytoin and Carbamazepine. | Pharmacy world & science : PWS 20050601 |
| [Electrophysiological monitoring of epileptic patients treated with Vigabatrin]. | Journal francais d'ophtalmologie 20050601 |
| Pharmacological and behavioral characteristics of interactions between vigabatrin and conventional antiepileptic drugs in pentylenetetrazole-induced seizures in mice: an isobolographic analysis. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050501 |
| Beneficial interaction between vigabatrin and valproate against seizures induced by pentylenetetrazole in mice. | Pharmacological research 20050501 |
| GABAergic modulation of the expression of genes involved in GABA synaptic transmission and stress in the hypothalamus and telencephalon of the female goldfish (Carassius auratus). | Journal of neuroendocrinology 20050501 |
| Selective GABAergic treatment for panic? Investigations in experimental panic induction and panic disorder. | Journal of psychiatry & neuroscience : JPN 20050501 |
| Evaluation of health status in epilepsy using the EQ-5D questionnaire: a prospective, observational, 6-month study of adjunctive therapy with anti-epileptic drugs. | Current medical research and opinion 20050501 |
| Quantitative determination of vigabatrin and gabapentin in human serum by gas chromatography-mass spectrometry. | Clinica chimica acta; international journal of clinical chemistry 20050401 |
| The safety and effectiveness of newer antiepileptics: a comparative postmarketing cohort study. | Journal of clinical pharmacology 20050401 |
| The latest on infantile spasms. | Current opinion in neurology 20050401 |
| Clinical effectiveness, tolerability and cost-effectiveness of newer drugs for epilepsy in adults: a systematic review and economic evaluation. | Health technology assessment (Winchester, England) 20050401 |
| Novel anticonvulsants in the treatment of alcoholism. | Expert opinion on investigational drugs 20050401 |
| Nitric oxide stimulates gamma-aminobutyric acid release and inhibits glycine release in retina. | The Journal of comparative neurology 20050314 |
| Profile of West syndrome in North Indian children. | Brain & development 20050301 |
| The use of lamotrigine, vigabatrin and gabapentin as add-on therapy in intractable epilepsy of childhood. | Seizure 20050301 |
| [Linear nevus sebaceous syndrome with hemimegalencephaly diagnosed in child in neonatal period]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20050301 |
| Safety and efficacy of gamma-vinyl GABA (GVG) for the treatment of methamphetamine and/or cocaine addiction. | Synapse (New York, N.Y.) 20050201 |
| Elevated endogenous GABA level correlates with decreased fMRI signals in the rat brain during acute inhibition of GABA transaminase. | Journal of neuroscience research 20050201 |
| Catecholamine depletion modulates serum LH levels, GAD67 mRNA, and GABA synthesis in the goldfish. | General and comparative endocrinology 20050201 |
| Reduced visual function associated with infantile spasms in children on vigabatrin therapy. | Investigative ophthalmology & visual science 20050201 |
| Analysis of antiepileptic drugs in biological fluids by means of electrokinetic chromatography. | Electrophoresis 20050201 |
| The relationship between hippocampal EEG theta activity and locomotor behaviour in freely moving rats: effects of vigabatrin. | Brain research bulletin 20050130 |
| GABA shunt deficiencies and accumulation of reactive oxygen intermediates: insight from Arabidopsis mutants. | FEBS letters 20050117 |
| The natural history of Vigabatrin associated visual field defects in patients electing to continue their medication. | Eye (London, England) 20050101 |
| Mechanisms of action of antiepileptic drugs. | Current topics in medicinal chemistry 20050101 |
| Antiepileptic action induced by a combination of vigabatrin and tiagabine. | Neuroscience 20050101 |
| [Treatment of West syndrome]. | Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti 20050101 |
| [Electroencephalography in status epilepticus in sleep (ESES) in various clinical pictures]. | Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti 20050101 |
| Effect of levetiracetam on the pharmacokinetics of adjunctive antiepileptic drugs: a pooled analysis of data from randomized clinical trials. | Epilepsy research 20050101 |
| Effect of maternal administration of vigabatrin during late gestation on fetoplacental amino acid profile in the mouse. | Reproductive toxicology (Elmsford, N.Y.) 20050101 |
| Antiepileptic drugs in mood-disordered patients. | Epilepsia 20050101 |
| Ion channels and epilepsy. | Current pharmaceutical design 20050101 |
| Pharmacokinetic interactions of carbamazepine with some antiepileptic drugs during epilepsy treatment in children and adolescents. | Roczniki Akademii Medycznej w Bialymstoku (1995) 20050101 |
| New antiepileptic drugs--an overview. | Roczniki Akademii Medycznej w Bialymstoku (1995) 20050101 |
| A comparative study of vigabatrin vs. carbamazepine in monotherapy of newly diagnosed partial seizures in children. | Pharmacological reports : PR 20050101 |
| [The efficacy of topiramate (topamax) in the treatment of resistant epilepsy in children]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20050101 |
| The effects of vigabatrin on rat liver antioxidant status. | Drug metabolism and drug interactions 20050101 |
| Management of Landau-Kleffner syndrome. | Paediatric drugs 20050101 |
| Role of opioidergic mechanisms and GABA uptake inhibition in the heroin-induced discriminative stimulus effects in rats. | Pharmacological reports : PR 20050101 |
| Comprehensive analysis of pyrimidine metabolism in 450 children with unspecific neurological symptoms using high-pressure liquid chromatography-electrospray ionization tandem mass spectrometry. | Journal of inherited metabolic disease 20050101 |
| [Epilepsy with polymorphic seizures in hospitalized children]. | Przeglad lekarski 20050101 |
| [The function of eye and vision system in children and youth treated with vigabatrin--our own experiences]. | Klinika oczna 20050101 |
| [Current pharmacotherapy of epilepsy in adults]. | Bulletin de la Societe des sciences medicales du Grand-Duche de Luxembourg 20050101 |
| Gamma-vinyl GABA (vigabatrin) blocks the expression of toluene-induced conditioned place preference (CPP). | Synapse (New York, N.Y.) 20041201 |
| Effect of Vigabatrin on motor responses to transcranial magnetic stimulation: an effective tool to investigate in vivo GABAergic cortical inhibition in humans. | Brain research 20041126 |
| Early treatment of Aicardi syndrome with vigabatrin can improve outcome. | Neurology 20041109 |
| Conformationally-restricted vigabatrin analogs as irreversible and reversible inhibitors of gamma-aminobutyric acid aminotransferase. | Bioorganic & medicinal chemistry 20041101 |
| The United Kingdom Infantile Spasms Study comparing vigabatrin with prednisolone or tetracosactide at 14 days: a multicentre, randomised controlled trial. | Lancet (London, England) 20041101 |
| Simultaneous high-performance liquid chromatographic analysis of pregabalin, gabapentin and vigabatrin in human serum by precolumn derivatization with o-phtaldialdehyde and fluorescence detection. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041025 |
| Visual field constriction associated with vigabatrin: retinal nerve fiber layer photographic correlation. | Journal of neurology, neurosurgery, and psychiatry 20041001 |
| Efficacy and tolerability of the new antiepileptic drugs: comparison of two recent guidelines. | The Lancet. Neurology 20041001 |
| A new strategy for in vivo spectral editing. Application to GABA editing using selective homonuclear polarization transfer spectroscopy. | Journal of magnetic resonance (San Diego, Calif. : 1997) 20041001 |
| Characteristic retinal atrophy with secondary 'inverse' optic atrophy identifies vigabatrin toxicity in children. | Ophthalmology 20041001 |
| Anticonvulsant drugs in primary headaches prophylaxis. | Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20041001 |
| Increased GAD67 mRNA levels are correlated with in vivo GABA synthesis in the MPTP-treated catecholamine-depleted goldfish brain. | Brain research. Molecular brain research 20040928 |
| Alpha 5 subunit-containing GABAA receptors affect the dynamic range of mouse hippocampal kainate-induced gamma frequency oscillations in vitro. | The Journal of physiology 20040915 |
| The effect of GABA and the GABA-uptake-blocker NO-711 on the b-wave of the ERG and the responses of horizontal cells to light. | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20040901 |
| Acute vigabatrin retinotoxicity in albino rats depends on light but not GABA. | Epilepsia 20040901 |
| Vigabatrin and tiagabine might have antipanic properties. | Journal of psychopharmacology (Oxford, England) 20040901 |
| Drug selection for the newly diagnosed patient: when is a new generation antiepileptic drug indicated? | Journal of neurology 20040901 |
| Managing epilepsy in tuberous sclerosis complex. | Journal of child neurology 20040901 |
| Crystal structures of unbound and aminooxyacetate-bound Escherichia coli gamma-aminobutyrate aminotransferase. | Biochemistry 20040831 |
| Altered GABAB receptor immunoreactivity in the gerbil hippocampus induced by baclofen and phaclofen, not seizure activity. | Neuroscience research 20040801 |
| Synthesis of cyclopropane isosteres of the antiepilepsy drug vigabatrin and evaluation of their inhibition of GABA aminotransferase. | Journal of enzyme inhibition and medicinal chemistry 20040801 |
| The interaction between vigabatrin and diazepam on the electroencephalogram during active behaviour in rats: an isobolic analysis. | European journal of pharmacology 20040714 |
| Simultaneous determination of vigabatrin and amino acid neurotransmitters in brain microdialysates by capillary electrophoresis with laser-induced fluorescence detection. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040705 |
| Altered Na+-K+ ATPase immunoreactivity within GABAergic neurons in the gerbil hippocampal complex induced by spontaneous seizure and vigabatrin treatment. | Neurochemistry international 20040701 |
| Development of vigabatrin-induced lesions in the rat brain studied by magnetic resonance imaging, histology, and immunocytochemistry. | Synapse (New York, N.Y.) 20040701 |
| The activity of antiepileptic drugs as histone deacetylase inhibitors. | Epilepsia 20040701 |
| Subacute sclerosing panencephalitis: a case with fulminant course after ACTH. | Pediatric neurology 20040701 |
| Are vigabatrin-associated visual field constrictions asymptomatic? | Journal of neurology 20040701 |
| Transcranial magnetic stimulation: applications for neuropsychopharmacology. | Journal of psychopharmacology (Oxford, England) 20040601 |
| Spectrum of epilepsy in tuberous sclerosis. | Neurology India 20040601 |
| [Treatment protocol for long-term anti-epilepsy drugs in adults with refractory partial epilepsy]. | Revue neurologique 20040601 |
| The effect of Vigabatrin, Lamotrigine and Gabapentin on the fertility, weights, sex hormones and biochemical profiles of male rats. | Neuro endocrinology letters 20040601 |
| Infantile spasms: therapy and outcome. | Journal of child neurology 20040601 |
| New pharmacotherapies for pediatric seizures. | Pediatric annals 20040601 |
| Practice parameter: medical treatment of infantile spasms: report of the American Academy of Neurology and the Child Neurology Society. | Neurology 20040525 |
| Design, synthesis and anticonvulsive activity of analogs of gamma-vinyl GABA. | Farmaco (Societa chimica italiana : 1989) 20040501 |
| Vigabatrin, the GABA-transaminase inhibitor, damages cone photoreceptors in rats. | Annals of neurology 20040501 |
| Perinatal exposure to GABA-transaminase inhibitor impaired psychomotor function in the developing and adult mouse. | International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20040501 |
| Drugs and the retina. | Expert opinion on drug safety 20040501 |
| Combined treatment with vigabatrin and topiramate in West syndrome. | Journal of child neurology 20040501 |
| Brain GABA editing by localized in vivo (1)H magnetic resonance spectroscopy. | NMR in biomedicine 20040401 |
| Scotopic threshold response changes after vigabatrin therapy in a child without visual field defects: a new electroretinographic marker of early damage? | Neurobiology of disease 20040401 |
| Adverse effects of new antiepileptic drugs. | Drugs of today (Barcelona, Spain : 1998) 20040401 |
| Determination of vigabatrin in human plasma and urine by high-performance liquid chromatography with UV-Vis detection. | Journal of chromatography. A 20040326 |
| Biphasic action of vigabatrin on cortical epileptic after-discharges in rats. | Naunyn-Schmiedeberg's archives of pharmacology 20040301 |
| Interaction between anticonvulsants and human placental carnitine transporter. | Epilepsia 20040301 |
| The effect of antiepileptic drugs on visual performance. | Seizure 20040301 |
| Alterations in electroretinograms and retinal morphology in rabbits treated with vigabatrin. | Documenta ophthalmologica. Advances in ophthalmology 20040301 |
| Vigabatrin inhibits pyridoxine-5'-phosphate oxidase, not pyridoxal kinase in the hippocampus of seizure prone gerbils. | Neurochemistry international 20040201 |
| Vigabatrin-induced modification of Ki-67 expression in gingival epithelium: immunohistochemical study of a short series. | Journal of periodontal research 20040201 |
| Coactivation of GABA(A) and GABA(B) receptor results in neuroprotection during in vitro ischemia. | Stroke 20040201 |
| Vigabatrin-associated loss of vision: rarebit perimetry illuminates the dose-damage relationship. | Acta ophthalmologica Scandinavica 20040201 |
| Structures of gamma-aminobutyric acid (GABA) aminotransferase, a pyridoxal 5'-phosphate, and [2Fe-2S] cluster-containing enzyme, complexed with gamma-ethynyl-GABA and with the antiepilepsy drug vigabatrin. | The Journal of biological chemistry 20040102 |
| Behavioural effects of the newer antiepileptic drugs: an update. | Expert opinion on drug safety 20040101 |
| Treatment of partial seizures in childhood : an overview. | CNS drugs 20040101 |
| New antiepileptic agents. | Pediatric dentistry 20040101 |
| The central piriform cortex: anatomical connections and anticonvulsant effect of GABA elevation in the kindling model. | Neuroscience 20040101 |
| Agents in development for the management of cocaine abuse. | Drugs 20040101 |
| Role of the GABA transporter in epilepsy. | Advances in experimental medicine and biology 20040101 |
| Pharmacologic treatment of the catastrophic epilepsies. | Epilepsia 20040101 |
| Succinic semialdehyde dehydrogenase deficiency (SSADH) (4-hydroxybutyric aciduria, gamma-hydroxybutyric aciduria). | European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20040101 |
| The time-frequency structure of the spike-wave discharges in genetic absence epilepsy. | Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20040101 |
| Bilateral microinjections of vigabatrin in the central piriform cortex retard amygdala kindling in rats. | Neuroscience 20040101 |
| Progress report on new antiepileptic drugs: a summary of the Seventh Eilat Conference (EILAT VII). | Epilepsy research 20040101 |
| Therapeutic drug monitoring of old and newer anti-epileptic drugs. | Clinical chemistry and laboratory medicine 20040101 |
| [Neuroprotective activity of antiepileptic drugs]. | Przeglad lekarski 20040101 |
| Peripheral retinal dysfunction in patients taking vigabatrin. | Neurology 20031223 |
| Design, synthesis, and biological activity of a difluoro-substituted, conformationally rigid vigabatrin analogue as a potent gamma-aminobutyric acid aminotransferase inhibitor. | Journal of medicinal chemistry 20031204 |
| Positron emission tomography studies of potential mechanisms underlying phencyclidine-induced alterations in striatal dopamine. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20031201 |
| Treating cocaine addiction: from preclinical to clinical trial experience with gamma-vinyl GABA. | Synapse (New York, N.Y.) 20031201 |
| [Vigabatrin in the treatment of epilepsy in patients with West syndrome and tuberous sclerosis]. | Arquivos de neuro-psiquiatria 20031201 |
| Monitoring of 4-hydroxybutyric acid levels in body fluids during vigabatrin treatment in succinic semialdehyde dehydrogenase deficiency. | Annals of neurology 20031101 |
| Infantile spasms. | Expert opinion on pharmacotherapy 20031101 |
| Effects of antiepileptic drugs on refractory seizures in the intact immature corticohippocampal formation in vitro. | Epilepsia 20031101 |
| Examining visual field defects in the paediatric population exposed to vigabatrin. | Documenta ophthalmologica. Advances in ophthalmology 20031101 |
| Longitudinal changes in photopic OPs occurring with vigabatrin treatment. | Documenta ophthalmologica. Advances in ophthalmology 20031101 |
| Changes in the electroretinogram resulting from discontinuation of vigabatrin in children. | Documenta ophthalmologica. Advances in ophthalmology 20031101 |
| Sensorineural hearing loss: a reversible effect of vigabatrin. | Neurology 20031014 |
| Boosting GABA improves impaired auditory temporal resolution in the gerbil. | Neuroreport 20031006 |
| Vigabatrin: longterm follow-up of electrophysiology and visual field examinations. | Acta ophthalmologica Scandinavica 20031001 |
| Characterization of vigabatrin-associated optic atrophy. | Acta ophthalmologica Scandinavica 20031001 |
| Design, synthesis and anticonvulsive activities of potential prodrugs linked by two-carbon chain. | Archives of pharmacal research 20031001 |
| Visual field defects in pediatric patients on vigabatrin monotherapy. | Documenta ophthalmologica. Advances in ophthalmology 20030901 |
| Determination of vigabatrin by capillary electrophoresis with laser-induced fluorescence detection. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030825 |
| P2X2 and P2X4 receptor expression is regulated by a GABA(A) receptor-mediated mechanism in the gerbil hippocampus. | Brain research. Molecular brain research 20030819 |
| GABA transporters and GABA-transaminase as drug targets. | Current drug targets. CNS and neurological disorders 20030801 |
| Serum concentrations and effects of gabapentin and vigabatrin: observations from a dose titration study. | Therapeutic drug monitoring 20030801 |
| Treatment of infantile spasms: the ideal and the mundane. | Epilepsia 20030801 |
| Short-term nonhormonal and nonsteroid treatment in West syndrome. | Epilepsia 20030801 |
| The importance of being seizure free: topiramate and psychopathology in epilepsy. | Epilepsy & behavior : E&B 20030801 |
| Kinetic studies on the inhibition of GABA-T by gamma-vinyl GABA and taurine. | Journal of enzyme inhibition and medicinal chemistry 20030801 |
| Analgesia and hyperalgesia from GABA-mediated modulation of the cerebral cortex. | Nature 20030717 |
| Sub-chronic low dose gamma-vinyl GABA (vigabatrin) inhibits cocaine-induced increases in nucleus accumbens dopamine. | Psychopharmacology 20030701 |
| Acute effects of gabapentin and pregabalin on rat forebrain cellular GABA, glutamate, and glutamine concentrations. | Seizure 20030701 |
| Vigabatrin, but not gabapentin or topiramate, produces concentration-related effects on enzymes and intermediates of the GABA shunt in rat brain and retina. | Epilepsia 20030701 |
| [Significance of GABAA receptors for the pathophysiology and therapy of panic disorders]. | Der Nervenarzt 20030701 |
| Successful pregnancy in a patient with hyperoxaluria and combined liver and renal transplant. | Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 20030701 |
| Clinical trials of antiepileptic medications in newly diagnosed patients with epilepsy. | Neurology 20030610 |
| Effect of vigabatrin on contractile response to arachidonic acid and prostaglandins in smooth muscle preparations and platelet aggregation in experimental laboratory animals. | Pharmacological research 20030601 |
| Therapeutic drug monitoring of the newer antiepileptic drugs. | Therapeutic drug monitoring 20030601 |
| Simultaneous isocratic HPLC determination of vigabatrin and gabapentin in human plasma by dansyl derivatization. | Therapeutic drug monitoring 20030601 |
| Retinal function abnormalities in patients treated with vigabatrin. | Archives of ophthalmology (Chicago, Ill. : 1960) 20030601 |
| Clinically important drug interactions in epilepsy: general features and interactions between antiepileptic drugs. | The Lancet. Neurology 20030601 |
| GABA-ergic drugs: exit stage left, enter stage right. | Journal of psychopharmacology (Oxford, England) 20030601 |
| Glutaryl-CoA dehydrogenase deficiency: region-specific analysis of organic acids and acylcarnitines in post mortem brain predicts vulnerability of the putamen. | Neuropediatrics 20030601 |
| Infantile spasms with basal ganglia MRI hypersignal may reveal mitochondrial disorder due to T8993G MT DNA mutation. | Neuropediatrics 20030601 |
| The evidence for GABAB receptor-mediated regulation of acid-base balance: involvement of Na+/H+ exchanger and Na+/HCO3- cotransporter. | Brain research. Molecular brain research 20030526 |
| Effects of alprazolam on cholecystokinin-tetrapeptide-induced panic and hypothalamic-pituitary-adrenal-axis activity: a placebo-controlled study. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030501 |
| [Vigabatrin-associated bilateral simple optic nerve atrophy with visual field constriction. A case report and a survey of the literature]. | Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20030501 |
| Experimental anxiety and antiepileptics: the effects of valproate and vigabatrin in the mirrored chamber test. | Methods and findings in experimental and clinical pharmacology 20030501 |
| Antiepileptic drugs and apoptosis in the developing brain. | Annals of the New York Academy of Sciences 20030501 |
| The ideal pharmacokinetic properties of an antiepileptic drug: how close does levetiracetam come? | Epileptic disorders : international epilepsy journal with videotape 20030501 |
| Effect of vigabatrin on glutamate dehydrogenase in the hippocampus of seizure prone gerbils. | Neuroscience letters 20030410 |
| Vigabatrin induces tonic inhibition via GABA transporter reversal without increasing vesicular GABA release. | Journal of neurophysiology 20030401 |
| Failure of ischemic neuroprotection by potentiators of gamma-aminobutyric acid. | Clinical medicine & research 20030401 |
| [New epileptic treatments. Current modalities and their utilization]. | Presse medicale (Paris, France : 1983) 20030308 |
| The effects of vigabatrin on type II spike wave discharges in rats. | Neuroscience letters 20030306 |
| [Vigabatrin and visual field defects. A Danish material with evaluation of different screening methods]. | Ugeskrift for laeger 20030303 |
| Vigabatrin, tiagabine, and visual fields. | Journal of neurology, neurosurgery, and psychiatry 20030301 |
| A controlled study comparing visual function in patients treated with vigabatrin and tiagabine. | Journal of neurology, neurosurgery, and psychiatry 20030301 |
| Responsiveness of the quality of life in epilepsy inventory (QOLIE-89) in an antiepileptic drug trial. | Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation 20030301 |
| Prospective preliminary analysis of the development of autism and epilepsy in children with infantile spasms. | Journal of child neurology 20030301 |
| Pre-clinical studies with the GABAergic compounds vigabatrin and tiagabine. | Epileptic disorders : international epilepsy journal with videotape 20030301 |
| Protein 4.1N is required for translocation of inositol 1,4,5-trisphosphate receptor type 1 to the basolateral membrane domain in polarized Madin-Darby canine kidney cells. | The Journal of biological chemistry 20030207 |
| Immunohistochemistry as a tool for topographical semi-quantification of neurotransmitters in the brain. | Brain research. Brain research protocols 20030201 |
| Effects of antiepileptic comedication on levetiracetam pharmacokinetics: a pooled analysis of data from randomized adjunctive therapy trials. | Epilepsy research 20030201 |
| In vivo monitoring of rat brain metabolites during vigabatrin treatment using localized 2D-COSY. | NMR in biomedicine 20030201 |
| Novel mechanisms of action of three antiepileptic drugs, vigabatrin, tiagabine, and topiramate. | Neurochemical research 20030201 |
| Vigabatrin-associated visual field constriction in a longitudinal series. Reversibility suggested after drug withdrawal. | Acta ophthalmologica Scandinavica 20030201 |
| Changed vesicular GABA transporter immunoreactivity in the gerbil hippocampus following spontaneous seizure and vigabatrin administration. | Neuroscience letters 20030102 |
| Epilepsy patients treated with vigabatrin exhibit reduced ocular blood flow. | The British journal of ophthalmology 20030101 |
| The absorption of gabapentin following high dose escalation. | Seizure 20030101 |
| Effects of vigabatrin on brain GABA+/Cr signals in focus-distant and focus-near brain regions monitored by 1H-NMR spectroscopy. | European journal of neurology 20030101 |
| Anti-epileptic drugs-induced de novo absence seizures. | Brain & development 20030101 |
| Interlaboratory variability in the quantification of new generation antiepileptic drugs based on external quality assessment data. | Epilepsia 20030101 |
| Selection criteria for the clinical use of the newer antiepileptic drugs. | CNS drugs 20030101 |
| Vigabatrin and newer interventions in succinic semialdehyde dehydrogenase deficiency. | Annals of neurology 20030101 |
| Treatment of infantile spasms. | The Cochrane database of systematic reviews 20030101 |
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| Angelman syndrome: etiology, clinical features, diagnosis, and management of symptoms. | Paediatric drugs 20030101 |
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| Modulation of the in vivo effects of gabapentin by vigabatrin and SKF89976A. | Epilepsy research 20021201 |
| Pre- rather than co-application of vigabatrin increases the efficacy of tiagabine in hippocampal slices. | Epilepsia 20021201 |
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| The promise of new antiepileptic drugs. | British journal of clinical pharmacology 20020201 |
| The effect of water temperature on the GABAergic and reproductive systems in female and male goldfish (Carassius auratus). | General and comparative endocrinology 20020201 |
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| Pd asymmetric allylic alkylation (AAA). A powerful synthetic tool. | Chemical & pharmaceutical bulletin 20020101 |
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| Newer antiepileptic drugs: advantages and disadvantages. | Brain & development 20010801 |
| Is hyperprolinemia type I actually a benign trait? Report of a case with severe neurologic involvement and vigabatrin intolerance. | Journal of child neurology 20010801 |
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| Gabapentin but not vigabatrin is effective in the treatment of acquired nystagmus in multiple sclerosis: How valid is the GABAergic hypothesis? | Journal of neurology, neurosurgery, and psychiatry 20010701 |
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| Development of a stable-isotope dilution assay for gamma-aminobutyric acid (GABA) transaminase in isolated leukocytes and evidence that GABA and beta-alanine transaminases are identical. | Clinical chemistry 20010301 |
| Chronic elevation of brain GABA levels beginning two days after status epilepticus does not prevent epileptogenesis in rats. | Neuropharmacology 20010301 |
| Placental transfer of vigabatrin (gamma-vinyl GABA) and its effect on concentration of amino acids in the embryo of TO mice. | Teratology 20010301 |
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| Determination of the antiepileptics vigabatrin and gabapentin in dosage forms and biological fluids using Hantzsch reaction. | Arzneimittel-Forschung 20010201 |
| The effect of gamma-vinyl-GABA on the consumption of concurrently available oral cocaine and ethanol in the rat. | Pharmacology, biochemistry, and behavior 20010201 |
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| New developments in the pharmacotherapy of alcohol dependence. | The American journal on addictions 20010101 |
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| Bodyweight gain and anticonvulsants: a comparative review. | Drug safety 20010101 |
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