1-piperideine
| Title | Journal |
|---|---|
| One-pot catalytic enantioselective synthesis of tetrahydropyridines via a nitro-Mannich/hydroamination cascade. | Organic letters 20121019 |
| Discovery and SAR of orally efficacious tetrahydropyridopyridazinone PARP inhibitors for the treatment of cancer. | Bioorganic & medicinal chemistry 20120801 |
| Methyl 2,6-diphenyl-1-p-tolyl-4-(p-tolyl-amino)-1,2,5,6-tetra-hydro-pyridine-3-carboxyl-ate. | Acta crystallographica. Section E, Structure reports online 20120801 |
| Modulating the reactivity of functionalized N,S-ketene acetal in MCR: selective synthesis of tetrahydropyridines and thiochromeno[2,3-b]pyridines via DABCO-catalyzed tandem annulation. | The Journal of organic chemistry 20120504 |
| 2-(4-Amino-phen-yl)-3,4,5,6-tetra-hydro-pyrimidin-1-ium chloride. | Acta crystallographica. Section E, Structure reports online 20120501 |
| 6-Meth-oxy-1-(4-meth-oxy-phen-yl)-1,2,3,4-tetra-hydro-9H-β-carbolin-2-ium acetate. | Acta crystallographica. Section E, Structure reports online 20120501 |
| Bis(6-meth-oxy-1-methyl-2,3,4,9-tetra-hydro-1H-β-carbolin-2-ium) tetra-chloridozincate(II) dihydrate. | Acta crystallographica. Section E, Structure reports online 20120401 |
| 5-(2-Chloro-benz-yl)-4,5,6,7-tetra-hydro-thieno[3,2-c]pyridin-2-yl acetate. | Acta crystallographica. Section E, Structure reports online 20120401 |
| Initial hydrogenations of pyridine on MoP(001): a density functional study. | Langmuir : the ACS journal of surfaces and colloids 20120214 |
| Discovery of 7-arylsulfonyl-1,2,3,4, 4a,9a-hexahydro-benzo[4,5]furo[2,3-c]pyridines: identification of a potent and selective 5-HT₆ receptor antagonist showing activity in rat social recognition test. | Bioorganic & medicinal chemistry letters 20120201 |
| Relevance of animal models to human tardive dyskinesia. | Behavioral and brain functions : BBF 20120101 |
| Cholesteryl ester transfer-protein modulator and inhibitors and their potential for the treatment of cardiovascular diseases. | Vascular health and risk management 20120101 |
| Lobelia siphilitica plants that escape herbivory in time also have reduced latex production. | PloS one 20120101 |
| Time-dependent slowly-reversible inhibition of monoamine oxidase A by N-substituted 1,2,3,6-tetrahydropyridines. | Bioorganic & medicinal chemistry 20111215 |
| Lose weight with traditional chinese medicine? Potential suppression of fat mass and obesity-associated protein. | Journal of biomolecular structure & dynamics 20111201 |
| 2-(5-Bromo-pyridin-3-yl)-5-[3-(4,5,6,7-tetra-hydro-thieno[3,2-c]pyridine-5-ylsulfon-yl)thio-phen-2-yl]-1,3,4-oxa-diazole. | Acta crystallographica. Section E, Structure reports online 20111001 |
| 2-(Biphenyl-4-yl)-5-[3-(4,5,6,7-tetra-hydro-thieno[3,2-c]pyridine-5-ylsulfon-yl)thio-phen-2-yl]-1,3,4-oxa-diazole. | Acta crystallographica. Section E, Structure reports online 20111001 |
| Parkinson's disease mouse models in translational research. | Mammalian genome : official journal of the International Mammalian Genome Society 20110801 |
| 2-[4-(4-Methylphenylsulfonyl)piperazin-1-yl]-1-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)ethanone. | Acta crystallographica. Section E, Structure reports online 20110801 |
| The styrene metabolite, phenylglyoxylic acid, induces striatal-motor toxicity in the rat: influence of dose escalation/reduction over time. | Neurotoxicity research 20110701 |
| Ethyl 1-[2-(1H-benzotriazol-1-yl)acet-yl]-4-hy-droxy-2,6-diphenyl-1,2,5,6-tetra-hydro-pyridine-3-carboxyl-ate. | Acta crystallographica. Section E, Structure reports online 20110701 |
| Ethyl 1-[2-(1,3-benzoxazol-2-ylsulfan-yl)acet-yl]-4-hy-droxy-2,6-diphenyl-1,2,5,6-tetra-hydro-pyridine-3-carboxyl-ate. | Acta crystallographica. Section E, Structure reports online 20110701 |
| Hyperbolic mixed-type inhibition of acetylcholinesterase by tetracyclic thienopyrimidines. | Journal of enzyme inhibition and medicinal chemistry 20110601 |
| N-(5-Ethylsulfanyl-1,3,4-thiadiazol-2-yl)-2-(4,5,6,7-tetrahydrothieno[3,2-c]pyri-din-5-yl)acetamide. | Acta crystallographica. Section E, Structure reports online 20110601 |
| Neuroprotection: the emerging concept of restorative neural stem cell biology for the treatment of neurodegenerative diseases. | Current neuropharmacology 20110601 |
| 3-Indolylacyl radical cyclizations upon pyridines and tetrahydropyridines: access to ergoline-related indole [cd]-fused isoquinolines. | The Journal of organic chemistry 20110520 |
| Facile and unified approach to skeletally diverse, privileged scaffolds. | Organic letters 20110520 |
| 3-(5-Chloro-naphthalene-1-sulfonamido)-2-(2-hy-droxy-eth-yl)-4,5,6,7-tetra-hydro-2H-pyrazolo-[4,3-c]pyridin-5-ium chloride. | Acta crystallographica. Section E, Structure reports online 20110501 |
| Biotin tethered homotryptamine derivatives: high affinity probes of the human serotonin transporter (hSERT). | Bioorganic & medicinal chemistry letters 20110315 |
| Ethyl 1-benzoyl-4-hy-droxy-2,6-diphenyl-1,2,5,6-tetra-hydro-pyridine-3-carboxyl-ate. | Acta crystallographica. Section E, Structure reports online 20110301 |
| Preclinical pharmacokinetics and metabolism of MNP001, a piperidine analog of 3-carbamyl compounds. | Biopharmaceutics & drug disposition 20110101 |
| Synthesis of some nucleosides derivatives from L- rhamnose with expected biological activity. | Chemistry Central journal 20110101 |
| The biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's disease. | International journal of molecular sciences 20110101 |
| Ethyl 2-amino-6-benzyl-4,5,6,7-tetra-hydro-thieno[2,3-c]pyridine-3-carboxyl-ate. | Acta crystallographica. Section E, Structure reports online 20110101 |
| Conformationally constrained histidines in the design of peptidomimetics: strategies for the χ-space control. | International journal of molecular sciences 20110101 |
| Identification and characterization of mechanism of action of P61-E7, a novel phosphine catalysis-based inhibitor of geranylgeranyltransferase-I. | PloS one 20110101 |
| 2-Chloro-1-(4,5,6,7-tetrahydro-thieno[3,2-c]pyridin-5-yl)ethanone. | Acta crystallographica. Section E, Structure reports online 20101201 |
| 1-Acetyl-2-r,6-c-bis-(4-chloro-phen-yl)-3-methyl-1,2,5,6-tetra-hydro-pyridin-4-yl acetate. | Acta crystallographica. Section E, Structure reports online 20101201 |
| Aminopyrazine inhibitors binding to an unusual inactive conformation of the mitotic kinase Nek2: SAR and structural characterization. | Journal of medicinal chemistry 20101111 |
| 1-(2,2-Dimeth-oxy-eth-yl)-8-nitro-1,2,3,5,6,7-hexa-hydro-imidazo[1,2-a]pyridin-5-ol. | Acta crystallographica. Section E, Structure reports online 20100901 |
| Tetrahydropyridine derivatives with inhibitory activity on the production of proinflammatory cytokines: part 3. | Bioorganic & medicinal chemistry letters 20100815 |
| Ethyl 4-hy-droxy-2,6-diphenyl-1-(2-thio-morpholino-acet-yl)-1,2,5,6-tetra-hydro-pyridine-3-carboxyl-ate. | Acta crystallographica. Section E, Structure reports online 20100801 |
| Ethyl 4-hy-droxy-2,6-diphenyl-1-[2-(piperidin-1-yl)acet-yl]-1,2,5,6-tetra-hydro-pyridine-3-carboxyl-ate. | Acta crystallographica. Section E, Structure reports online 20100801 |
| A computational study of the binding of 3-(arylidene) anabaseines to two major brain nicotinic acetylcholine receptors and to the acetylcholine binding protein. | European journal of medicinal chemistry 20100601 |
| Prasugrel, a new medicine for preventing blockages in the arteries. | Acta crystallographica. Section E, Structure reports online 20100601 |
| 8a-Methyl-5,6,8,8a,9,10-hexa-hydro-10,12a-epoxy-isoindolo[1,2-a]isoquinolinium iodide. | Acta crystallographica. Section E, Structure reports online 20100601 |
| Tetrahydropyridine derivatives with inhibitory activity on the production of proinflammatory cytokines: part 2. | Bioorganic & medicinal chemistry letters 20100415 |
| 2'-Methyl-3,5-diphenyl-spiro-[4,6-dioxa-2-aza-bicyclo-[3.2.0]hept-2-ene-7,4'-iso-quinoline]-1',3'(2'H,4'H)-dione. | Acta crystallographica. Section E, Structure reports online 20100401 |
| 9-Furfuryl-idene-2,3-dimethyl-6,7,8,9-tetrahydro-4H--thieno[2',3':4,5]pyrimidino[1,2-a]pyridin-4-one. | Acta crystallographica. Section E, Structure reports online 20100301 |
| 2-Ethyl-6-(2-pyrid-yl)-5,6,6a,11b-tetra-hydro-7H-indeno[2,1-c]quinoline. | Acta crystallographica. Section E, Structure reports online 20100301 |
| A versatile enantioselective synthesis of barrenazines. | Organic letters 20100219 |
| Molecular modeling study of 4-phenylpiperazine and 4-phenyl-1,2,3,6-tetrahydropyridine derivatives: a new step towards the design of high-affinity 5-HT1A ligands. | Bioorganic & medicinal chemistry letters 20100201 |
| Synthesis of 3-alkyl pyridinium alkaloids from the arctic sponge Haliclona viscosa. | Marine drugs 20100101 |
| The S100B/RAGE Axis in Alzheimer's Disease. | Cardiovascular psychiatry and neurology 20100101 |
| Lead expansion and virtual screening of Indinavir derivate HIV-1 protease inhibitors using pharmacophoric - shape similarity scoring function. | Bioinformation 20100101 |
| α7 Nicotinic Receptor Agonists: Potential Therapeutic Drugs for Treatment of Cognitive Impairments in Schizophrenia and Alzheimer's Disease. | The open medicinal chemistry journal 20100101 |
| Methyl 7,8-diacet-oxy-11-oxo-5-(2-oxo-pyrrolidin-1-yl)-7,9-epoxy-cyclo-penta-[4,5]pyrido[1,2-a]quinoline-10-carboxyl-ate sesquihydrate. | Acta crystallographica. Section E, Structure reports online 20100101 |
| 3-Benzyl-7-chloro-9-phenyl-2-tosyl-2,3,3a,4,9,9a-hexa-hydro-1H-pyrrolo[3,4-b]quinoline. | Acta crystallographica. Section E, Structure reports online 20091201 |
| 3-Benzyl-7-bromo-9-phenyl-2-tosyl-2,3,3a,4,9,9a-hexa-hydro-1H-pyrrolo[3,4-b]quinoline. | Acta crystallographica. Section E, Structure reports online 20091201 |
| Ethyl 4-hydr-oxy-2,6-diphenyl-1-(2-thio-morpholinopropano-yl)-1,2,5,6-tetra-hydro-pyridine-3-carboxyl-ate. | Acta crystallographica. Section E, Structure reports online 20091201 |
| Ethyl 4-hydr-oxy-1-(2-morpholinopro-pano-yl)-2,6-diphenyl-1,2,5,6-tetra-hydro-pyridin-3-carboxyl-ate. | Acta crystallographica. Section E, Structure reports online 20091201 |
| Pyrazole-based cathepsin S inhibitors with arylalkynes as P1 binding elements. | Bioorganic & medicinal chemistry letters 20091101 |
| 3-Benzyl-9-phenyl-2-tosyl-2,3,3a,4,9,9a-hexa-hydro-1H-pyrrolo[3,4-b]quinoline. | Acta crystallographica. Section E, Structure reports online 20091101 |
| 3-Benzyl-7-methyl-9-phenyl-2-tosyl-2,3,3a,4,9,9a-hexa-hydro-1H-pyrrolo[3,4-b]quinoline. | Acta crystallographica. Section E, Structure reports online 20091101 |
| 3-Benzyl-7-meth-oxy-9-phenyl-2-tosyl-2,3,3a,4,9,9a-hexa-hydro-1H-pyrrolo[3,4-b]quinoline. | Acta crystallographica. Section E, Structure reports online 20091101 |
| (E)-5-Bromo-3-(2,6-dichloro-benzyl-idene)indolin-2-one. | Acta crystallographica. Section E, Structure reports online 20090901 |
| Tetrahydropyridine derivatives with inhibitory activity on the production of proinflammatory cytokines: part 1. | Bioorganic & medicinal chemistry letters 20090815 |
| 4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-[2-(2-methyl-4-oxo-6,7,8,9-tetra-hydro-4H-pyrido[1,2-a]pyrimidin-3-yl)eth-yl]piperidinium nitrate. | Acta crystallographica. Section E, Structure reports online 20090701 |
| Ethyl 1-(2-bromo-propano-yl)-4-hydr-oxy-2,6-diphenyl-1,2,5,6-tetra-hydro-pyridine-3-carboxylate. | Acta crystallographica. Section E, Structure reports online 20090701 |
| Piperidine and tetrahydropyridine alkaloids from Lobelia siphilitica and Hippobroma longiflora. | Journal of natural products 20090227 |
| A facile synthesis, antibacterial, and antitubercular studies of some piperidin-4-one and tetrahydropyridine derivatives. | Bioorganic & medicinal chemistry letters 20081215 |
| Deuterium isotope effects for the oxidation of 1-methyl-3-phenyl-3-pyrrolinyl analogues by monoamine oxidase B. | Bioorganic & medicinal chemistry 20081001 |
| Tetrahydropyridine-4-carboxamides as novel, potent transient receptor potential vanilloid 1 (TRPV1) antagonists. | Bioorganic & medicinal chemistry 20080915 |
| 3-Ethyl 5-methyl 2-hydr-oxy-6-methyl-4-(4-nitro-phen-yl)-2-trifluoro-methyl-1,2,3,4-tetra-hydro-pyridine-3,5-dicarboxyl-ate. | Acta crystallographica. Section E, Structure reports online 20080901 |
| Natural products as an inspiration in the diversity-oriented synthesis of bioactive compound libraries. | Natural product reports 20080801 |
| [4 + 2] cycloadditions of N-alkenyl iminium ions: structurally complex heterocycles from a three-component Diels-Alder reaction sequence. | Journal of the American Chemical Society 20080723 |
| Effect of dopaminergic neurotoxin MPTP/MPP+ on coenzyme Q content. | Life sciences 20080718 |
| 3-(4-Chloro-phenyl-diazen-yl)-1-methyl-1,4,5,6-tetra-hydro-pyridine. | Acta crystallographica. Section E, Structure reports online 20080701 |
| New building block for polyhydroxylated piperidine: total synthesis of 1,6-dideoxynojirimycin. | The Journal of organic chemistry 20080404 |
| 7-Chloro-4-(2,5-dichloro-phen-yl)-1-phenyl-1H-thio-chromeno[2,3-b]pyridine-2,5(3H,4H)-dione. | Acta crystallographica. Section E, Structure reports online 20080401 |
| 3-Ethyl-9-phenyl-2-tosyl-2,3,3a,4,9,9a-hexahydro-1H-pyrrolo[3,4-b]quinoline. | Acta crystallographica. Section E, Structure reports online 20080201 |
| 7-Bromo-3-ethyl-9-phenyl-2-tosyl-pyrrolo[3,4-b]quinoline. | Acta crystallographica. Section E, Structure reports online 20080101 |
| Skeletal diversity through radical cyclization of tetrahydropyridine scaffolds. | Organic letters 20070913 |
| 4,6-Dimethyl-2-[(4-phenylpiperidin-1-yl)methyl]isothiazolo[5,4-b]pyridin-3(2H)-one and 4,6-dimethyl-2-[(4-phenyl-1,2,3,6-tetrahydropyridin-1-yl)methyl]isothiazolo[5,4-b]pyridin-3(2H)-one. | Acta crystallographica. Section C, Crystal structure communications 20070801 |
| Synthesis, insecticidal activity, and QSAR of novel nitromethylene neonicotinoids with tetrahydropyridine fixed cis configuration and exo-ring ether modification. | Journal of agricultural and food chemistry 20070321 |
| Synthesis of Novel 3-Aryl-N-Methyl-1,2,5,6-Tetrahydropyridine Derivatives by Suzuki coupling: As Acetyl Cholinesterase Inhibitors. | The open medicinal chemistry journal 20070101 |
| Reactivity of 4-tert-butyldimethylsiloxy-1,2,3,6-tetrahydropyridines with hydrazines. | Molecules (Basel, Switzerland) 20061130 |
| Golden times for allenes: Gold-catalyzed cycloisomerization of beta-hydroxyallenes to dihydropyrans. | Organic letters 20060928 |
| Regioselective 6-endo cyclizations of 2-indolylacyl radicals: total synthesis of the pyrido[4,3-b]carbazole alkaloid guatambuine. | The Journal of organic chemistry 20060217 |
| Diastereoselective synthesis of some novel benzopyranopyridine derivatives. | Beilstein journal of organic chemistry 20060101 |
| Synthesis of tricyclic 1,3-oxazin-4-ones and kinetic analysis of cholesterol esterase and acetylcholinesterase inhibition. | Journal of medicinal chemistry 20051229 |
| A new route to diverse 1-azasugars from N-Boc-5-hydroxy-3-piperidene as a common building block. | The Journal of organic chemistry 20050624 |
| Synthesis and structure-activity relationships of 4-alkynyloxy phenyl sulfanyl, sulfinyl, and sulfonyl alkyl hydroxamates as tumor necrosis factor-alpha converting enzyme and matrix metalloproteinase inhibitors. | Journal of medicinal chemistry 20041202 |
| Asymmetric total synthesis of (+)-cannabisativine. | The Journal of organic chemistry 20040806 |
| Estrogen and neuroprotection: higher constitutive expression of glutaredoxin in female mice offers protection against MPTP-mediated neurodegeneration. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040701 |
| Rearrangement of pyrrolines derived from the Birch reduction of electron-deficient pyrroles: radical ring-expansion to substituted tetrahydropyridines. | Chemical communications (Cambridge, England) 20040621 |
| New piperidine scaffolds via nucleophilic reactivity of (-)-phenyloxazolopiperidine. | The Journal of organic chemistry 20040528 |
| Endogenous and dietary indoles: a class of antioxidants and radical scavengers in the ABTS assay. | Free radical research 20040301 |
| Differing response to antipsychotic therapy in schizophrenia: pharmacogenomic aspects. | Dialogues in clinical neuroscience 20040301 |
| An aza-steroidal [17,16-c]pyrazole derivative: 2'-(p-fluorophenyl)-17a-aza-2'H-pyrazolo[4',3':16,17]-D-homoandrost-4-en-3-one. | Acta crystallographica. Section C, Crystal structure communications 20040201 |
| Characterization of novel dihydrothienopyridinium and thienopyridinium metabolites of ticlopidine in vitro: role of peroxidases, cytochromes p450, and monoamine oxidases. | Drug metabolism and disposition: the biological fate of chemicals 20040101 |
| Two azasteroidal [3,2-c]pyrazole derivatives: 2'-(p-fluorophenyl)-4-azapyrazolo[4',3':2,3]-5alpha-androstan-17beta-yl acetate and 2'-(p-fluorophenyl)-4-azapyrazolo[4',3':2,3]-5alpha-androstan-17beta-ol. | Acta crystallographica. Section C, Crystal structure communications 20031201 |
| Synthesis and in vitro biological evaluation of fluoro-substituted-4-phenyl-1,2,3,6-tetrahydropyridines as monoamine oxidase B substrates. | Bioorganic & medicinal chemistry 20031117 |
| Stereoselective aza-Diels-Alder reactions with 2H-azirines as dienophiles furnishing highly functionalized tetrahydropyridines. | Chemical communications (Cambridge, England) 20030521 |
| Aryl tetrahydropyridine inhibitors of farnesyltransferase: glycine, phenylalanine and histidine derivatives. | Bioorganic & medicinal chemistry letters 20030407 |
| Aryl tetrahydropyridine inhibitors of farnesyltransferase: bioavailable analogues with improved cellular potency. | Bioorganic & medicinal chemistry letters 20030407 |
| 2-nitroso-1,3-diphenyl-1,2,3,4-tetrahydrobenzo[b][1,6]naphthyridine. | Acta crystallographica. Section C, Crystal structure communications 20030301 |
| Highly enantioenriched tetrahydropyridines from chiral organosilanes: application to the synthesis of quinolizidine alkaloid (-)-217A. | Journal of the American Chemical Society 20030122 |
| Synthesis and anti-inflammatory activities of N-benzoylamino-1,2,3,6-tetrahydropyridine analogs. | Drugs under experimental and clinical research 20030101 |
| 2-Hydroxy-3-(4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridin-5-ium-4-yl)benzoate monohydrate. | Acta crystallographica. Section C, Crystal structure communications 20021201 |
| Cycloaddition reaction of 2-azadienes derived from beta-amino acids with electron-rich and electron-deficient alkenes and carbonyl compounds. Synthesis of pyridine and 1,3-oxazine derivatives. | The Journal of organic chemistry 20020405 |
| 1,3-Dimethyl-2-oxo-4,6-diphenyl-1,2,3,4-tetrahydropyridine-3-carbonitrile. | Acta crystallographica. Section C, Crystal structure communications 20020301 |
| Endogenous alkaloids in man. XXXVIII. 'Chiral' and 'achiral' determination of the neurotoxin TaClo (1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline) from blood and urine samples by high-performance liquid chromatography--electrospray ionization tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020215 |
| Pyridophens: binary pyridostigmine-aprophen prodrugs with differential inhibition of acetylcholinesterase, butyrylcholinesterase, and muscarinic receptors. | Journal of medicinal chemistry 20020214 |
| Identification of metabolites of fluorine-18-labeled M2 muscarinic receptor agonist, 3-(3-[(3-fluoropropyl)thio]-1,2,5-thiadiazol-4-yl)-1,2,5,6-tetrahydro-1-methylpyridine, produced by human and rat hepatocytes. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020125 |
| In vitro characterization of the metabolism of haloperidol using recombinant cytochrome p450 enzymes and human liver microsomes. | Drug metabolism and disposition: the biological fate of chemicals 20011201 |
| Incorporation of a molecular hinge into molecular tweezers by using tandem cycloadditions onto 5,6-dimethylenenorbornene. | Chemistry (Weinheim an der Bergstrasse, Germany) 20010803 |
| Catabolism of L-lysine by Pseudomonas aeruginosa. | Journal of general microbiology 19770301 |