1,3-Dichloro-2-propanone
Title | Journal |
---|---|
A novel structural rearrangement reaction of dialkylated derivatives of [Pt2(μ-S)2(PPh3)4] involving Pt-C bond formation. | Dalton transactions (Cambridge, England : 2003) 20121107 |
Autoproteolytic activation of ThnT results in structural reorganization necessary for substrate binding and catalysis. | Journal of molecular biology 20120928 |
TPCK inhibits AGC kinases by direct activation loop adduction at phenylalanine-directed cysteine residues. | FEBS letters 20120921 |
A 'Link-Psi' strategy using crosslinking indicates that the folding transition state of ubiquitin is not very malleable. | Protein science : a publication of the Protein Society 20120601 |
Pathogen-mediated proteolysis of the cell death regulator RIPK1 and the host defense modulator RIPK2 in human aortic endothelial cells. | PLoS pathogens 20120601 |
Investigation of the proteolytic functions of an expanded cercarial elastase gene family in Schistosoma mansoni. | PLoS neglected tropical diseases 20120401 |
Direct NMR observation and pKa determination of the Asp102 side chain in a serine protease. | Journal of the American Chemical Society 20120201 |
A P-loop mutation in Gα subunits prevents transition to the active state: implications for G-protein signaling in fungal pathogenesis. | PLoS pathogens 20120201 |
Novel marine phenazines as potential cancer chemopreventive and anti-inflammatory agents. | Marine drugs 20120201 |
Selenium-containing amino acids are targets for myeloperoxidase-derived hypothiocyanous acid: determination of absolute rate constants and implications for biological damage. | The Biochemical journal 20120101 |
Interleukin-1 participates in the classical and alternative activation of microglia/macrophages after spinal cord injury. | Journal of neuroinflammation 20120101 |
Mutational analysis of Cvab, an ABC transporter involved in the secretion of active colicin V. | PloS one 20120101 |
Mechanisms of intramolecular communication in a hyperthermophilic acylaminoacyl peptidase: a molecular dynamics investigation. | PloS one 20120101 |
Live imaging of mitosomes and hydrogenosomes by HaloTag technology. | PloS one 20120101 |
A novel sLRP6E1E2 inhibits canonical Wnt signaling, epithelial-to-mesenchymal transition, and induces mitochondria-dependent apoptosis in lung cancer. | PloS one 20120101 |
Biochemical aspects of a serine protease from Caesalpinia echinata Lam. (Brazilwood) seeds: a potential tool to access the mobilization of seed storage proteins. | TheScientificWorldJournal 20120101 |
Cysteine peptidases, secreted by Trichomonas gallinae, are involved in the cytopathogenic effects on a permanent chicken liver cell culture. | PloS one 20120101 |
Prenatal hyperandrogenization induces metabolic and endocrine alterations which depend on the levels of testosterone exposure. | PloS one 20120101 |
A coevolutionary residue network at the site of a functionally important conformational change in a phosphohexomutase enzyme family. | PloS one 20120101 |
Formation of nitrogenous disinfection by-products from pre-chloramination. | Chemosphere 20111101 |
Labdane diterpenes protect against anoxia/reperfusion injury in cardiomyocytes: involvement of AKT activation. | Cell death & disease 20111101 |
Regulation of osteoarthritis by omega-3 (n-3) polyunsaturated fatty acids in a naturally occurring model of disease. | Osteoarthritis and cartilage 20110901 |
In vivo detection of Staphylococcus aureus endocarditis by targeting pathogen-specific prothrombin activation. | Nature medicine 20110901 |
1,3-Bis{[5-(pyridin-2-yl)-1,3,4-oxadiazol-2-yl]sulfan-yl}propan-2-one. | Acta crystallographica. Section E, Structure reports online 20110201 |
HSV neutralization by the microbicidal candidate C5A. | PloS one 20110101 |
The nucleosome (histone-DNA complex) is the TLR9-specific immunostimulatory component of Plasmodium falciparum that activates DCs. | PloS one 20110101 |
The Differential Effect of Toxoplasma Gondii Infection on the Stability of BCL2-Family Members Involves Multiple Activities. | Frontiers in microbiology 20110101 |
Por secretion system-dependent secretion and glycosylation of Porphyromonas gingivalis hemin-binding protein 35. | PloS one 20110101 |
The nucleotide exchange factor Ric-8A is a chaperone for the conformationally dynamic nucleotide-free state of Gαi1. | PloS one 20110101 |
Lipopolysaccharide and tumor necrosis factor regulate Parkin expression via nuclear factor-kappa B. | PloS one 20110101 |
Protein kinases and phosphatases in the control of cell fate. | Enzyme research 20110101 |
3D QSAR pharmacophore modeling, in silico screening, and density functional theory (DFT) approaches for identification of human chymase inhibitors. | International journal of molecular sciences 20110101 |
Mackerel trypsin purified from defatted viscera by supercritical carbon dioxide. | Journal of amino acids 20110101 |
Elevated levels of activated and inactivated thrombin-activatable fibrinolysis inhibitor in patients with sepsis. | The Korean journal of hematology 20101201 |
Natural and synthetic inhibitors of kallikrein-related peptidases (KLKs). | Biochimie 20101101 |
A general scheme for synthesis of substrate-based polyketide labels for acyl carrier proteins. | Bioorganic & medicinal chemistry letters 20101001 |
Functional divergence of platelet protein kinase C (PKC) isoforms in thrombus formation on collagen. | The Journal of biological chemistry 20100723 |
Role of vimA in cell surface biogenesis in Porphyromonas gingivalis. | Microbiology (Reading, England) 20100701 |
Effects of acute insulin-induced hypoglycemia on indices of inflammation: putative mechanism for aggravating vascular disease in diabetes. | Diabetes care 20100701 |
Inositol hexakisphosphate-induced autoprocessing of large bacterial protein toxins. | PLoS pathogens 20100701 |
The PB2-E627K mutation attenuates viruses containing the 2009 H1N1 influenza pandemic polymerase. | mBio 20100401 |
Annexin-II, DNA, and histones serve as factor H ligands on the surface of apoptotic cells. | The Journal of biological chemistry 20100205 |
Spatial distribution of factor Xa, thrombin, and fibrin(ogen) on thrombi at venous shear. | PloS one 20100101 |
Characterization of hemin-binding protein 35 (HBP35) in Porphyromonas gingivalis: its cellular distribution, thioredoxin activity and role in heme utilization. | BMC microbiology 20100101 |
Bacterial and human peptidylarginine deiminases: targets for inhibiting the autoimmune response in rheumatoid arthritis? | Arthritis research & therapy 20100101 |
Chloroquine potentiates the anti-cancer effect of 5-fluorouracil on colon cancer cells. | BMC cancer 20100101 |
Alkylating HIV-1 Nef - a potential way of HIV intervention. | AIDS research and therapy 20100101 |
A critical tryptophan and Ca2+ in activation and catalysis of TPPI, the enzyme deficient in classic late-infantile neuronal ceroid lipofuscinosis. | PloS one 20100101 |
Expression of a novel chimeric truncated t-PA in CHO cells based on in silico experiments. | Journal of biomedicine & biotechnology 20100101 |
Bovipain-2, the falcipain-2 ortholog, is expressed in intraerythrocytic stages of the tick-transmitted hemoparasite Babesia bovis. | Parasites & vectors 20100101 |
Cucurbitacin I inhibits cell motility by indirectly interfering with actin dynamics. | PloS one 20100101 |
An evaluation of the chick cardiomyocyte micromass system for identification of teratogens in a blind trial. | Reproductive toxicology (Elmsford, N.Y.) 20091201 |
Quantitative assessment of DNA replication to monitor microgametogenesis in Plasmodium berghei. | Molecular and biochemical parasitology 20091201 |
N-tosyl-L-phenylalanine chloromethyl ketone inhibits NF-kappaB activation by blocking specific cysteine residues of IkappaB kinase beta and p65/RelA. | Biochemistry 20090804 |
Mechanical and kinetic effects of shortened tropomyosin reconstituted into myofibrils. | Pflugers Archiv : European journal of physiology 20090801 |
Catalytic activity and inhibition of wegener antigen proteinase 3 on the cell surface of human polymorphonuclear neutrophils. | The Journal of biological chemistry 20090724 |
Mechanisms of growth inhibition in human papillomavirus positive and negative cervical cancer cells by the chloromethyl ketone protease inhibitor, succinyl-alanine-alanine-proline-phenylalanine chloromethyl ketone. | The Journal of pharmacology and experimental therapeutics 20090701 |
The role of Bcl-xL and nuclear factor-kappaB in the effect of taxol on the viability of dendritic cells. | Journal of veterinary science 20090601 |
The Stimulation of CD147 Induces MMP-9 Expression through ERK and NF-kappaB in Macrophages: Implication for Atherosclerosis. | Immune network 20090601 |
Nicastrin is dispensable for gamma-secretase protease activity in the presence of specific presenilin mutations. | The Journal of biological chemistry 20090508 |
Selectivity profiling of DegP substrates and inhibitors. | Bioorganic & medicinal chemistry 20090401 |
NtCP56, a new cysteine protease in Nicotiana tabacum L., involved in pollen grain development. | Journal of experimental botany 20090401 |
Protoporphyrin IX enhancement by 5-aminolaevulinic acid peptide derivatives and the effect of RNA silencing on intracellular metabolism. | British journal of cancer 20090310 |
Insect chymotrypsins: chloromethyl ketone inactivation and substrate specificity relative to possible coevolutional adaptation of insects and plants. | Archives of insect biochemistry and physiology 20090301 |
Metabolic acidosis increases intracellular calcium in bone cells through activation of the proton receptor OGR1. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20090201 |
Synthesis and biological evaluation of a chitobiose-based peptide N-glycanase inhibitor library. | The Journal of organic chemistry 20090116 |
Regulation of chemerin bioactivity by plasma carboxypeptidase N, carboxypeptidase B (activated thrombin-activable fibrinolysis inhibitor), and platelets. | The Journal of biological chemistry 20090109 |
Distinct roles of Plasmodium rhomboid 1 in parasite development and malaria pathogenesis. | PLoS pathogens 20090101 |
Purification and characterization of a serine protease (CESP) from mature coconut endosperm. | BMC research notes 20090101 |
HIV-1 Tat co-operates with IFN-gamma and TNF-alpha to increase CXCL10 in human astrocytes. | PloS one 20090101 |
IgG autoantibody to brain beta tubulin III associated with cytokine cluster-II discriminate cerebral malaria in central India. | PloS one 20090101 |
Digestive proteolytic activity in the Sunn pest, Eurygaster integriceps. | Journal of insect science (Online) 20090101 |
Eptifibatide: The evidence for its role in the management of acute coronary syndromes. | Core evidence 20090101 |
Treatment with N-tosyl-l-phenylalanine chloromethyl ketone after the onset of collagen-induced arthritis reduces joint erosion and NF-kappaB activation. | European journal of pharmacology 20081024 |
Bone-derived SDF-1 stimulates IL-6 release via CXCR4, ERK and NF-kappaB pathways and promotes osteoclastogenesis in human oral cancer cells. | Carcinogenesis 20080801 |
Protective effects of recombinant kunitz-domain 1 of human tissue factor pathway inhibitor-2 against 2-chloroethyl ethyl sulfide toxicity in vitro. | Eplasty 20080101 |
A prevalent variant in PPP1R3A impairs glycogen synthesis and reduces muscle glycogen content in humans and mice. | PLoS medicine 20080101 |
Anti-chaperone betaA3/A1(102-117) peptide interacting sites in human alphaB-crystallin. | Molecular vision 20080101 |
Neutrophil elastase reduces secretion of secretory leukoproteinase inhibitor (SLPI) by lung epithelial cells: role of charge of the proteinase-inhibitor complex. | Respiratory research 20080101 |
A novel bioluminescent protease assay using engineered firefly luciferase. | Current chemical genomics 20080101 |
Intramolecular cross-linking evaluated as a structural probe of the protein folding transition state. | Biochemistry 20071204 |
Photochemical degradation of 1,3-dichloro-2-propanol aqueous solutions. | Journal of hazardous materials 20070731 |
Mesangial cells of lupus-prone mice are sensitive to chemokine production. | Arthritis research & therapy 20070101 |
Protective effects of recombinant kunitz-domain 1 of human tissue factor pathway inhibitor-2 against 2-chloroethyl ethyl sulfide toxicity in vitro. | Journal of burns and wounds 20070101 |
The oncolytic effect in vivo of reovirus on tumour cells that have survived reovirus cell killing in vitro. | British journal of cancer 20061023 |
Photocatalytical degradation of 1,3-dichloro-2-propanol aqueous solutions by using an immobilized TiO2 photoreactor. | Journal of hazardous materials 20060921 |
A protease inhibitor specifically inhibits growth of HPV-infected keratinocytes. | Molecular therapy : the journal of the American Society of Gene Therapy 20060601 |
A novel surface protein of Trichomonas vaginalis is regulated independently by low iron and contact with vaginal epithelial cells. | BMC microbiology 20060101 |
New insight into CCN3 interactions--nuclear CCN3 : fact or fantasy? | Cell communication and signaling : CCS 20060101 |
Natural and derivative brevetoxins: historical background, multiplicity, and effects. | Environmental health perspectives 20050501 |
Increased heat shock protein 70 expression following toxicant-mediated cytotoxicity: a ubiquitous marker of toxicant exposure? | Alternatives to laboratory animals : ATLA 20050401 |
Synthesis of classical, three-carbon-bridged 5-substituted furo[2,3-d]pyrimidine and 6-substituted pyrrolo[2,3-d]pyrimidine analogues as antifolates. | Journal of medicinal chemistry 20041230 |
Do alkylating agents modify the histidine residue of the desensitized butyrylcholinesterase? | The protein journal 20041101 |
Killing of schistosomes by elastase and hydrogen peroxide: implications for leukocyte-mediated schistosome killing. | The Journal of parasitology 20031201 |
Chemo-enzymatic synthesis of levodropropizine. | Farmaco (Societa chimica italiana : 1989) 20031001 |
The envelopes of amphibian oocytes: physiological modifications in Bufo arenarum. | Reproductive biology and endocrinology : RB&E 20030101 |
Mass spectrometric analysis of electrophoretically separated allergens and proteases in grass pollen diffusates. | Respiratory research 20030101 |
A model of tripeptidyl-peptidase I (CLN2), a ubiquitous and highly conserved member of the sedolisin family of serine-carboxyl peptidases. | BMC structural biology 20030101 |
The relative embryotoxicity of 1,3-dichloro-2-propanol on primary chick embryonic cells. | Toxicology in vitro : an international journal published in association with BIBRA 20020801 |
Modulation of hepatocyte thiol content by medium composition: implications for toxicity studies. | Toxicology in vitro : an international journal published in association with BIBRA 20020601 |
Investigation of the behaviour of haloketones in water samples. | Chemosphere 20010801 |
Effect of serine protease inhibitors on posttraumatic brain injury and neuronal apoptosis. | Experimental neurology 20010201 |
Linear competitive inhibition of human tissue kallikrein by 4-aminobenzamidine and benzamidine and linear mixed inhibition by 4-nitroaniline and aniline. | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20010101 |
Involvement of cytochrome P4502E1 in the toxicity of dichloropropanol to rat hepatocyte cultures. | Toxicology 19970328 |