Home Other Building Blocks Edonerpic maleate

Edonerpic maleate

CAS No.:
519187-97-4
Catalog Number:
AG00DKD5
Molecular Formula:
C20H25NO6S
Molecular Weight:
407.4806
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1mg
98%
1 week
United States
$140
- +
5mg
98%
1 week
United States
$196
- +
10mg
98%
1 week
United States
$265
- +
50mg
98%
1 week
United States
$737
- +
100mg
98%
1 week
United States
$1237
- +
Product Description
Catalog Number:
AG00DKD5
Chemical Name:
Edonerpic maleate
CAS Number:
519187-97-4
Molecular Formula:
C20H25NO6S
Molecular Weight:
407.4806
MDL Number:
MFCD13152397
IUPAC Name:
1-[3-[2-(1-benzothiophen-5-yl)ethoxy]propyl]azetidin-3-ol;(Z)-but-2-enedioic acid
InChI:
InChI=1S/C16H21NO2S.C4H4O4/c18-15-11-17(12-15)6-1-7-19-8-4-13-2-3-16-14(10-13)5-9-20-16;5-3(6)1-2-4(7)8/h2-3,5,9-10,15,18H,1,4,6-8,11-12H2;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChI Key:
RLUCYBFCLXANSO-BTJKTKAUSA-N
SMILES:
OC(=O)/C=C\C(=O)O.OC1CN(C1)CCCOCCc1ccc2c(c1)ccs2
UNII:
0LB9F7I5P3
Properties
Complexity:
415  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
1  
Exact Mass:
407.14g/mol
Formal Charge:
0
Heavy Atom Count:
28  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
407.481g/mol
Monoisotopic Mass:
407.14g/mol
Rotatable Bond Count:
9  
Topological Polar Surface Area:
136A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
T-817MA, a novel neurotrophic agent, ameliorates loss of GABAergic parvalbumin-positive neurons and sensorimotor gating deficits in rats transiently exposed to MK-801 in the neonatal period. Journal of psychiatric research 20120501
T-817MA, a neuroprotective agent, attenuates the motor and cognitive impairments associated with neuronal degeneration in P301L tau transgenic mice. Biochemical and biophysical research communications 20110422
[Pharmacological properties of T-817MA, a novel neurotrophic agent, for treatment of Alzheimer's disease.]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20100701
T-817MA, a neurotrophic agent, ameliorates the deficits in adult neurogenesis and spatial memory in rats infused i.c.v. with amyloid-beta peptide. British journal of pharmacology 20090601
A neuroprotective agent, T-817MA (1-{3-[2-(1-benzothiophen-5-yl)ethoxy]propyl} azetidin-3-ol maleate), prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in mice. Neuropharmacology 20081001
Neuroprotective effects of T-817MA against noise-induced hearing loss. Neuroscience research 20080501
T-817MA, a novel neurotrophic compound, ameliorates phencyclidine-induced disruption of sensorimotor gating. Psychopharmacology 20080401
Ameliorative effects of a neuroprotective agent, T-817MA, on place learning deficits induced by continuous infusion of amyloid-beta peptide (1-40) in rats. Hippocampus 20070101
T-817MA, a novel neurotrophic agent, improves sodium nitroprusside-induced mitochondrial dysfunction in cortical neurons. Neurochemistry international 20060101
A novel neurotrophic agent, T-817MA [1-{3-[2-(1-benzothiophen-5-yl) ethoxy] propyl}-3-azetidinol maleate], attenuates amyloid-beta-induced neurotoxicity and promotes neurite outgrowth in rat cultured central nervous system neurons. The Journal of pharmacology and experimental therapeutics 20050701
Properties