Home Other Building Blocks (1,2-DIAMINOCYCLOHEXANE)PLATINUM(II) CHLORIDE

(1,2-DIAMINOCYCLOHEXANE)PLATINUM(II) CHLORIDE

CAS No.:
52691-24-4
Catalog Number:
AG00DJ70
Molecular Formula:
C6H14Cl2N2Pt
Molecular Weight:
380.1728
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Product Description
Catalog Number:
AG00DJ70
Chemical Name:
(1,2-DIAMINOCYCLOHEXANE)PLATINUM(II) CHLORIDE
CAS Number:
52691-24-4
Molecular Formula:
C6H14Cl2N2Pt
Molecular Weight:
380.1728
MDL Number:
MFCD00058826
IUPAC Name:
cyclohexane-1,2-diamine;dichloroplatinum
InChI:
InChI=1S/C6H14N2.2ClH.Pt/c7-5-3-1-2-4-6(5)8;;;/h5-6H,1-4,7-8H2;2*1H;/q;;;+2/p-2
InChI Key:
PNNCIXRVXCLADM-UHFFFAOYSA-L
SMILES:
NC1CCCCC1N.[Cl-].[Cl-].[Pt+2]
Properties
Complexity:
65.7  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
379.018g/mol
Formal Charge:
0
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
380.176g/mol
Monoisotopic Mass:
379.018g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
52A^2
Undefined Atom Stereocenter Count:
2  
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
Bioactive polymeric metallosomes self-assembled through block copolymer-metal complexation. Journal of the American Chemical Society 20120815
Polymeric micelles incorporating (1,2-diaminocyclohexane)platinum (II) suppress the growth of orthotopic scirrhous gastric tumors and their lymph node metastasis. Journal of controlled release : official journal of the Controlled Release Society 20120430
Visible drug delivery by supramolecular nanocarriers directing to single-platformed diagnosis and therapy of pancreatic tumor model. Cancer research 20100915
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Cross-links of quadruplex structures from human telomeric DNA by dinuclear platinum complexes show the flexibility of both structures. Biochemistry 20050809
Preparation and biological properties of dichloro(1,2-diaminocyclohexane)platinum(II) (DACHPt)-loaded polymeric micelles. Journal of controlled release : official journal of the Controlled Release Society 20050103
Tamoxifen derivatives for delivery of the antitumoral (DACH)Pt group: selective synthesis by McMurry coupling, and biochemical behaviour. Chembiochem : a European journal of chemical biology 20030804
A platinum(IV) complex oxidizes guanine to 8-oxo-guanine in DNA and RNA. Inorganic chemistry 20011022
A possible explanation for a neurotoxic effect of the anticancer agent oxaliplatin on neuronal voltage-gated sodium channels. Journal of neurophysiology 20010501
Properties