DESIPRAMINE
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New therapeutic approaches and novel alternatives for organophosphate toxicity. | Toxicology letters 20180701 |
Application of a nonradioactive assay for high throughput screening for inhibition of thyroid hormone uptake via the transmembrane transporter MCT8. | Toxicology in vitro : an international journal published in association with BIBRA 20170401 |
Humanizing the zebrafish liver shifts drug metabolic profiles and improves pharmacokinetics of CYP3A4 substrates. | Archives of toxicology 20170301 |
The plasma membrane monoamine transporter (PMAT): Structure, function, and role in organic cation disposition. | Clinical pharmacology and therapeutics 20161101 |
Defining a role for acid sphingomyelinase in the p38/interleukin-6 pathway. | The Journal of biological chemistry 20140808 |
Selective inhibition of hepatitis C virus infection by hydroxyzine and benztropine. | Antimicrobial agents and chemotherapy 20140601 |
Refining the human iPSC-cardiomyocyte arrhythmic risk assessment model. | Toxicological sciences : an official journal of the Society of Toxicology 20131201 |
Inhibition of 2,4-dinitrofluorobenzene-induced contact hypersensitivity reaction by antidepressant drugs. | Pharmacological reports : PR 20130101 |
Analysis of region-specific changes in gene expression upon treatment with citalopram and desipramine reveals temporal dynamics in response to antidepressant drugs at the transcriptome level. | Psychopharmacology 20121001 |
The effects of isolated and enriched housing conditions on baseline and drug-induced behavioural responses in the male rat. | Behavioural brain research 20121001 |
Determination of desipramine in biological samples using liquid-liquid-liquid microextraction combined with in-syringe derivatization, gas chromatography, and nitrogen/phosphorus detection. | Journal of separation science 20121001 |
A reconstructed human epidermal keratinization culture model to characterize ceramide metabolism in the stratum corneum. | Archives of dermatological research 20120901 |
'Pre-cebo': an unrecognized issue in the interpretation of adequate relief during irritable bowel syndrome drug trials. | Journal of clinical gastroenterology 20120901 |
Comparative evaluation of the effect of tricyclic antidepressants on inducible nitric oxide synthase expression in neuropathic pain model. | Nitric oxide : biology and chemistry 20120815 |
Adrenergic stimulation-released 5-HT stored in adrenergic nerves inhibits CGRPergic nerve-mediated vasodilatation in rat mesenteric resistance arteries. | British journal of pharmacology 20120801 |
Effect of long-term caffeine administration on depressive-like behavior in rats exposed to chronic unpredictable stress. | Behavioural pharmacology 20120801 |
Depressive and cardiovascular disease comorbidity in a rat model of social stress: a putative role for corticotropin-releasing factor. | Psychopharmacology 20120701 |
Reduced tissue levels of noradrenaline are associated with behavioral phenotypes of the TgCRND8 mouse model of Alzheimer's disease. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20120701 |
Sildenafil, a phosphodiesterase type 5 inhibitor, enhances the antidepressant activity of amitriptyline but not desipramine, in the forced swim test in mice. | Journal of neural transmission (Vienna, Austria : 1996) 20120601 |
Inhibition of P-glycoprotein enhances transport of imipramine across the blood-brain barrier: microdialysis studies in conscious freely moving rats. | British journal of pharmacology 20120601 |
Sex differences in baseline and drug-induced behavioural responses in classical behavioural tests. | Progress in neuro-psychopharmacology & biological psychiatry 20120601 |
Noradrenergic antidepressant responses to desipramine in vivo are reciprocally regulated by arrestin3 and spinophilin. | Neuropharmacology 20120601 |
Effect of early life housing manipulation on baseline and drug-induced behavioural responses on neurochemistry in the male rat. | Progress in neuro-psychopharmacology & biological psychiatry 20120601 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. | Journal of medicinal chemistry 20120524 |
Thiamine is a substrate of organic cation transporters in Caco-2 cells. | European journal of pharmacology 20120505 |
The function of alpha-2-adrenoceptors in the rat locus coeruleus is preserved in the chronic constriction injury model of neuropathic pain. | Psychopharmacology 20120501 |
Comparison of ΔFosB immunoreactivity induced by vagal nerve stimulation with that caused by pharmacologically diverse antidepressants. | The Journal of pharmacology and experimental therapeutics 20120501 |
In vitro-to-in vivo predictions of drug-drug interactions involving multiple reversible inhibitors. | Expert opinion on drug metabolism & toxicology 20120401 |
Desipramine selectively potentiates norepinephrine-elicited ERK1/2 activation through the α2A adrenergic receptor. | Biochemical and biophysical research communications 20120330 |
The effects of nigrostriatal dopamine depletion on the thalamic parafascicular nucleus. | Brain research 20120329 |
Novel oxoisoaporphine-based inhibitors of acetyl- and butyrylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation. | Bioorganic & medicinal chemistry letters 20120315 |
Morris water maze performance deficit produced by intermittent swim stress is partially mediated by norepinephrine. | Pharmacology, biochemistry, and behavior 20120301 |
Reversed chloroquine molecules as a strategy to overcome resistance in malaria. | Current topics in medicinal chemistry 20120301 |
Difficulties in dopamine transporter radioligand PET analysis: the example of LBT-999 using [18F] and [11C] labelling Part I: PET studies. | Nuclear medicine and biology 20120201 |
A small chemical library of 2-aminoimidazole derivatives as BACE-1 inhibitors: Structure-based design, synthesis, and biological evaluation. | European journal of medicinal chemistry 20120201 |
On the improvement of inhibitory response control and visuospatial attention by indirect and direct adrenoceptor agonists. | Psychopharmacology 20120101 |
Magnesium deficiency induces anxiety and HPA axis dysregulation: modulation by therapeutic drug treatment. | Neuropharmacology 20120101 |
Platinum anticancer agents and antidepressants: desipramine enhances platinum-based cytotoxicity in human colon cancer cells. | Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20120101 |
Effects of noradrenergic denervation on L-DOPA-induced dyskinesia and its treatment by α- and β-adrenergic receptor antagonists in hemiparkinsonian rats. | Pharmacology, biochemistry, and behavior 20120101 |
Neuroprotective efficacy of quinazoline type phosphodiesterase 7 inhibitors in cellular cultures and experimental stroke model. | European journal of medicinal chemistry 20120101 |
Reactive metabolites of desipramine and clomipramine: The kinetics of formation and reactivity with DNA. | Bioorganic & medicinal chemistry 20120101 |
Neuroimmune endocrine effects of antidepressants. | Neuropsychiatric disease and treatment 20120101 |
Accumulation of an antidepressant in vesiculogenic membranes of yeast cells triggers autophagy. | PloS one 20120101 |
Primum non nocere: an evolutionary analysis of whether antidepressants do more harm than good. | Frontiers in psychology 20120101 |
Desipramine inhibits histamine H1 receptor-induced Ca2+ signaling in rat hypothalamic cells. | PloS one 20120101 |
Vagal nerve stimulation rapidly activates brain-derived neurotrophic factor receptor TrkB in rat brain. | PloS one 20120101 |
High dose methylphenidate treatment in adult attention deficit hyperactivity disorder: a case report. | Journal of medical case reports 20120101 |
Neonatal serotonin (5-HT) depletion does not affect spatial learning and memory in rats. | Pharmacological reports : PR 20120101 |
Role of AC-cAMP-PKA Cascade in Antidepressant Action of Electroacupuncture Treatment in Rats. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
Milnacipran inhibits glutamatergic N-methyl-D-aspartate receptor activity in spinal dorsal horn neurons. | Molecular pain 20120101 |
Inhibitory effect of antidepressant drugs on contact hypersensitivity reaction. | Pharmacological reports : PR 20120101 |
Desipramine pretreatment improves sympathetic remodeling and ventricular fibrillation threshold after myocardial ischemia. | Journal of biomedicine & biotechnology 20120101 |
Stimulatory effect of antidepressant drug pretreatment on progression of B16F10 melanoma in high-active male and female C57BL/6J mice. | Journal of neuroimmunology 20111215 |
Essential role for orbitofrontal serotonin 1B receptors in obsessive-compulsive disorder-like behavior and serotonin reuptake inhibitor response in mice. | Biological psychiatry 20111201 |
Case scenario: opioid association with serotonin syndrome: implications to the practitioners. | Anesthesiology 20111201 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). | PLoS computational biology 20111201 |
Regulation of CCL2/MCP-1 production in astrocytes by desipramine and atomoxetine: involvement of α2 adrenergic receptors. | Brain research bulletin 20111125 |
Serotonergic and noradrenergic pathways are required for the anxiolytic-like and antidepressant-like behavioral effects of repeated vagal nerve stimulation in rats. | Biological psychiatry 20111115 |
Antidepressants elevate GDNF expression and release from C₆ glioma cells in a β-arrestin1-dependent, CREB interactive pathway. | The international journal of neuropsychopharmacology 20111101 |
The antidepressant desipramine is an arrestin-biased ligand at the α(2A)-adrenergic receptor driving receptor down-regulation in vitro and in vivo. | The Journal of biological chemistry 20111014 |
Discovery of novel selective norepinephrine inhibitors: 1-(2-morpholin-2-ylethyl)-3-aryl-1,3-dihydro-2,1,3-benzothiadiazole 2,2-dioxides (WYE-114152). | Journal of medicinal chemistry 20111013 |
The triple reuptake inhibitor DOV216,303 exhibits limited antidepressant-like properties in the differential reinforcement of low-rate 72-second responding assay, likely due to dopamine reuptake inhibition. | Journal of psychopharmacology (Oxford, England) 20111001 |
Chronic desipramine treatment alters tyrosine hydroxylase but not norepinephrine transporter immunoreactivity in norepinephrine axons in the rat prefrontal cortex. | The international journal of neuropsychopharmacology 20111001 |
Desipramine treatment has minimal effects on the brain accumulation of glucocorticoids in P-gp-deficient and wild-type mice. | Psychoneuroendocrinology 20111001 |
Hybrids of oxoisoaporphine-tacrine congeners: novel acetylcholinesterase and acetylcholinesterase-induced β-amyloid aggregation inhibitors. | European journal of medicinal chemistry 20111001 |
Long-term ovariectomy modulates the antidepressant-like action of estrogens, but not of antidepressants. | Journal of psychopharmacology (Oxford, England) 20111001 |
Impact of chronic cyanosis and reoxygenation on the microheterogeneity of the myocardial blood flow: digital radiographic study in neonatal rats. | General thoracic and cardiovascular surgery 20111001 |
Rapid target-specific remodeling of fast-spiking inhibitory circuits after loss of dopamine. | Neuron 20110908 |
The disruption of central CO2 chemosensitivity in a mouse model of Rett syndrome. | American journal of physiology. Cell physiology 20110901 |
Stress modulation of cognitive and affective processes. | Stress (Amsterdam, Netherlands) 20110901 |
Ontogenetic serotoninergic lesioning alters histaminergic activity in rats in adulthood. | Neurotoxicity research 20110801 |
Behavioural effects of antidepressants are dependent and independent on the integrity of the dentate gyrus. | The international journal of neuropsychopharmacology 20110801 |
Predictive validity of a non-induced mouse model of compulsive-like behavior. | Behavioural brain research 20110801 |
Development of a highly sensitive cytotoxicity assay system for CYP3A4-mediated metabolic activation. | Drug metabolism and disposition: the biological fate of chemicals 20110801 |
Selective serotonin reuptake inhibitors attenuate the antigen presentation from dendritic cells to effector T lymphocytes. | FEMS immunology and medical microbiology 20110801 |
Citalopram versus desipramine in treatment resistant depression: effect of continuation or switching strategies: a randomized open study. | The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20110801 |
Intra-neuronal vesicular uptake of catecholamines is decreased in patients with Lewy body diseases. | The Journal of clinical investigation 20110801 |
Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2. | Journal of medicinal chemistry 20110714 |
Chronic unpredictable stress induces a reversible change of PER2 rhythm in the suprachiasmatic nucleus. | Brain research 20110705 |
Adoptive transfer of macrophage from mice with depression-like behavior enhances susceptibility to colitis. | Inflammatory bowel diseases 20110701 |
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk. | Cardiovascular research 20110701 |
Lipid raft-dependent activation of dual oxidase 1/H2O2/NF-κB pathway in bronchial epithelial cells. | American journal of physiology. Cell physiology 20110701 |
Species independence in brain tissue binding using brain homogenates. | Drug metabolism and disposition: the biological fate of chemicals 20110701 |
N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease. | European journal of medicinal chemistry 20110601 |
Fluoxetine, desipramine, and the dual antidepressant milnacipran reduce alcohol self-administration and/or relapse in dependent rats. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20110601 |
Importance of physicochemical properties for the design of new pesticides. | Journal of agricultural and food chemistry 20110413 |
Antidepressant-like action of intracerebral 6-fluoronorepinephrine, a selective full α-adrenoceptor agonist. | The international journal of neuropsychopharmacology 20110401 |
Electrospray ionization-ion mobility spectrometry as a detection system for three-phase hollow fiber microextraction technique and simultaneous determination of trimipramine and desipramine in urine and plasma samples. | Analytical and bioanalytical chemistry 20110401 |
Long-term body weight outcomes of antidepressant-environment interactions. | Molecular psychiatry 20110301 |
Treatment of depressive symptoms in Parkinson's disease. | European journal of neurology 20110301 |
Discovery of N-methyl-1-(1-phenylcyclohexyl)methanamine, a novel triple serotonin, norepinephrine, and dopamine reuptake inhibitor. | Bioorganic & medicinal chemistry letters 20110301 |
Automated experimental system capturing three behavioral components during murine forced swim test. | Life sciences 20110227 |
Pharmacologic treatment of depression in multiple sclerosis. | The Cochrane database of systematic reviews 20110216 |
Slow and incomplete sympathetic reinnervation of rat tail artery restores the amplitude of nerve-evoked contractions provided a perivascular plexus is present. | American journal of physiology. Heart and circulatory physiology 20110201 |
The effects of antidepressants on mitochondrial function in a model cell system and isolated mitochondria. | Neurochemical research 20110201 |
Effects of atomoxetine, desipramine, d-amphetamine and methylphenidate on impulsivity in juvenile rats, measured in a T-maze procedure. | Neuroscience letters 20110201 |
5,7,3'-Trihydroxy-3,4'-dimethoxyflavone inhibits the tubulin polymerization and activates the sphingomyelin pathway. | Molecular carcinogenesis 20110201 |
PET of (R)-11C-rolipram binding to phosphodiesterase-4 is reproducible and sensitive to increased norepinephrine in the rat heart. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20110201 |
[The delayed sensitization of CRH response developed after chronic variable stress on the acoustic startle reflex]. | Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20110201 |
Insulin modulates cocaine-sensitive monoamine transporter function and impulsive behavior. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20110126 |
Gilenya (FTY720) inhibits acid sphingomyelinase by a mechanism similar to tricyclic antidepressants. | Biochemical and biophysical research communications 20110107 |
Desipramine induces apoptosis in rat glioma cells via endoplasmic reticulum stress-dependent CHOP pathway. | Journal of neuro-oncology 20110101 |
Long-lasting cognitive deficit induced by stress is alleviated by acute administration of antidepressants. | Psychoneuroendocrinology 20110101 |
Synthesis and pharmacological evaluation of 4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalenyl amines as triple reuptake inhibitors. | Bioorganic & medicinal chemistry 20110101 |
Propionibacterium acnes CAMP factor and host acid sphingomyelinase contribute to bacterial virulence: potential targets for inflammatory acne treatment. | PloS one 20110101 |
Role of Striatum in the Pause and Burst Generation in the Globus Pallidus of 6-OHDA-Treated Rats. | Frontiers in systems neuroscience 20110101 |
Narcolepsy: a review. | Neuropsychiatric disease and treatment 20110101 |
Effects of Hypericum perforatum extract on rat irritable bowel syndrome. | Pharmacognosy magazine 20110101 |
Identification of bilateral changes in TID1 expression in the 6-OHDA rat model of Parkinson's disease. | PloS one 20110101 |
Lithium monotherapy increases ACTH and cortisol response in the DEX/CRH test in unipolar depressed subjects. A study with 30 treatment-naive patients. | PloS one 20110101 |
Neonatal serotonin (5-HT) depletion does not disrupt prepulse inhibition of the startle response in rats. | Pharmacological reports : PR 20110101 |
Reversal of myo-inositol metabolic level in the left dorsolateral prefrontal cortex of rats exposed to forced swimming test following desipramine treatment: an in vivo localized (1)H-MRS study at 4.7 T. | Magnetic resonance imaging 20101201 |
A predictive ligand-based Bayesian model for human drug-induced liver injury. | Drug metabolism and disposition: the biological fate of chemicals 20101201 |
Astrocytes in the retrotrapezoid nucleus sense H+ by inhibition of a Kir4.1-Kir5.1-like current and may contribute to chemoreception by a purinergic mechanism. | Journal of neurophysiology 20101201 |
Inhibition of norepinephrine reuptake and size of myocardial infarction during focal ischemia and after preconditioning. | Bulletin of experimental biology and medicine 20101201 |
Diaryldiamines with dual inhibition of the histamine H(3) receptor and the norepinephrine transporter and the efficacy of 4-(3-(methylamino)-1-phenylpropyl)-6-(2-(pyrrolidin-1-yl)ethoxy)naphthalen-1-ol in pain. | Journal of medicinal chemistry 20101111 |
Rigid analogues of the α2-adrenergic blocker atipamezole: small changes, big consequences. | Journal of medicinal chemistry 20101014 |
Forced swim test behavior in postpartum rats. | Pharmacology, biochemistry, and behavior 20101001 |
Involvement of threonine 258 and serine 259 motif in amphetamine-induced norepinephrine transporter endocytosis. | Journal of neurochemistry 20101001 |
Protective effect of desipramine, venlafaxine and trazodone against experimental animal model of transient global ischemia: possible involvement of NO-cGMP pathway. | Brain research 20100924 |
gamma-Aminobutyric acid-type A receptor deficits cause hypothalamic-pituitary-adrenal axis hyperactivity and antidepressant drug sensitivity reminiscent of melancholic forms of depression. | Biological psychiatry 20100915 |
Effects of antidepressants on the performance in the forced swim test of two psychogenetically selected lines of rats that differ in coping strategies to aversive conditions. | Psychopharmacology 20100901 |
Dexamethasone enhances the norepinephrine-induced ERK/MAPK intracellular pathway possibly via dysregulation of the alpha2-adrenergic receptor: implications for antidepressant drug mechanism of action. | European journal of cell biology 20100901 |
Intermittent and continuous swim stress-induced behavioral depression: sensitivity to norepinephrine- and serotonin-selective antidepressants. | Psychopharmacology 20100901 |
Beneficial effects of desipramine on cognitive function of chronically stressed rats are mediated by alpha1-adrenergic receptors in medial prefrontal cortex. | Progress in neuro-psychopharmacology & biological psychiatry 20100816 |
Desipramine attenuates forced swim test-induced behavioral and neurochemical alterations in mice: an in vivo(1)H-MRS study at 9.4T. | Brain research 20100812 |
In vivo voltammetric monitoring of catecholamine release in subterritories of the nucleus accumbens shell. | Neuroscience 20100811 |
HPC-1/syntaxin 1A gene knockout mice show abnormal behavior possibly related to a disruption in 5-HTergic systems. | The European journal of neuroscience 20100701 |
The tricyclic antidepressant desipramine inhibits T3 import into primary neurons. | Neuroscience letters 20100630 |
Discovery of novel selective norepinephrine reuptake inhibitors: 4-[3-aryl-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-1-(methylamino)butan-2-ols (WYE-103231). | Journal of medicinal chemistry 20100610 |
Sequential metabolism of secondary alkyl amines to metabolic-intermediate complexes: opposing roles for the secondary hydroxylamine and primary amine metabolites of desipramine, (s)-fluoxetine, and N-desmethyldiltiazem. | Drug metabolism and disposition: the biological fate of chemicals 20100601 |
Impact of lipid raft integrity on 5-HT3 receptor function and its modulation by antidepressants. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100601 |
Antidepressant-like or anxiolytic-like actions of topiramate alone or co-administered with intra-lateral septal infusions of neuropeptide Y in male Wistar rats. | Peptides 20100601 |
Effects of single and simultaneous lesions of serotonergic and noradrenergic pathways on open-space and bright-space anxiety-like behavior in two animal models. | Behavioural brain research 20100501 |
Heterocyclic cycloalkanol ethylamines as norepinephrine reuptake inhibitors. | Bioorganic & medicinal chemistry letters 20100501 |
Block of the human ether-a-go-go-related gene (hERG) K+ channel by the antidepressant desipramine. | Biochemical and biophysical research communications 20100409 |
Psychotropic drugs have contrasting skeletal effects that are independent of their effects on physical activity levels. | Bone 20100401 |
Vulnerability of peripheral catecholaminergic neurons to MPTP is not regulated by alpha-synuclein. | Neurobiology of disease 20100401 |
Regulation of MCP-1 production in brain by stress and noradrenaline-modulating drugs. | Journal of neurochemistry 20100401 |
1-(Indolin-1-yl)-1-phenyl-3-propan-2-olamines as potent and selective norepinephrine reuptake inhibitors. | Journal of medicinal chemistry 20100311 |
Treatment of resistant depression in patients with cancer with low doses of ketamine and desipramine. | Journal of palliative medicine 20100301 |
Nerve growth factor (NGF) has novel antidepressant-like properties in rats. | Pharmacology, biochemistry, and behavior 20100201 |
Dynamic monitoring of NET activity in mature murine sympathetic terminals using a fluorescent substrate. | British journal of pharmacology 20100201 |
[Uptake1 inibition in reperfusion: noradrenalin dynamic and myocardiola infraction size]. | Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20100201 |
Effects of extracellular pH reductions on [(3)H]D-aspartate and [(3)H]noradrenaline release by presynaptic nerve terminals isolated from rat cerebral cortex. | Journal of neural transmission (Vienna, Austria : 1996) 20100101 |
Transient supersensitivity to alpha-adrenoceptor agonists, and distinct hyper-reactivity to vasopressin and angiotensin II after denervation of rat tail artery. | British journal of pharmacology 20100101 |
Psychopharmacological neuroprotection in neurodegenerative disease: assessing the preclinical data. | The Journal of neuropsychiatry and clinical neurosciences 20100101 |
Functional Inhibitors of Acid Sphingomyelinase (FIASMAs): a novel pharmacological group of drugs with broad clinical applications. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101 |
Pharmacological interventions for antisocial personality disorder. | The Cochrane database of systematic reviews 20100101 |
Tetrabenazine: the first approved drug for the treatment of chorea in US patients with Huntington disease. | Neuropsychiatric disease and treatment 20100101 |
A new strategy for antidepressant prescription. | Frontiers in neuroscience 20100101 |
Antidepressant/anxiolytic and anti-nociceptive effects of novel 2-substituted 1,4-benzodiazepine-2-ones. | Scientia pharmaceutica 20100101 |
Inhibition of monoamine oxidase activity by antidepressants and mood stabilizers. | Neuro endocrinology letters 20100101 |
IFN-gamma reduction by tricyclic antidepressants. | International journal of psychiatry in medicine 20100101 |
Tryptophan, Neurodegeneration and HIV-Associated Neurocognitive Disorder. | International journal of tryptophan research : IJTR 20100101 |
Desipramine induced changes in the norepinephrine transporter, alpha- and gamma-synuclein in the hippocampus, amygdala and striatum. | Neuroscience letters 20091225 |
In vivo voltammetric monitoring of norepinephrine release in the rat ventral bed nucleus of the stria terminalis and anteroventral thalamic nucleus. | The European journal of neuroscience 20091203 |
The P2Y(1) and P2Y(12) receptors mediate autoinhibition of transmitter release in sympathetic innervated tissues. | Neurochemistry international 20091201 |
Desipramine inhibits the growth of a mouse skin squamous cell carcinoma cell line and affects glucocorticoid receptor-mediated transcription. | Molecular carcinogenesis 20091201 |
Effect of acute and repeated treatment with desipramine or methylphenidate on serial reversal learning in rats. | Neuropharmacology 20091201 |
Perisurgical amitriptyline produces a preventive effect on afferent hypersensitivity following spared nerve injury. | Pain 20091201 |
Neuroprotective and cholinergic properties of multifunctional glutamic acid derivatives for the treatment of Alzheimer's disease. | Journal of medicinal chemistry 20091126 |
Dual acting norepinephrine reuptake inhibitors and 5-HT(2A) receptor antagonists: Identification, synthesis and activity of novel 4-aminoethyl-3-(phenylsulfonyl)-1H-indoles. | Bioorganic & medicinal chemistry 20091115 |
Inhibitory effect of antidepressants on the NMDA-evoked [(3)H]noradrenaline release from rat hippocampal slices. | Neurochemistry international 20091101 |
MPTP-induced neuroblast apoptosis in the subventricular zone is not regulated by dopamine or other monoamine transporters. | Neurotoxicology 20091101 |
Tricyclic antidepressant toxicity treated with massive sodium bicarbonate. | The American journal of emergency medicine 20091101 |
Comparison of fused-core and conventional particle size columns by LC-MS/MS and UV: application to pharmacokinetic study. | Journal of pharmaceutical and biomedical analysis 20091015 |
Synthesis of 1,1-[1-naphthyloxy-2-thiophenyl]-2-methylaminomethylcyclopropanes and their evaluation as inhibitors of serotonin, norepinephrine, and dopamine transporters. | Journal of medicinal chemistry 20091008 |
Prefrontal cortical D1 dopamine receptors modulate subcortical D2 dopamine receptor-mediated stress responsiveness. | The international journal of neuropsychopharmacology 20091001 |
Structure-activity relationships of the 1-amino-3-(1H-indol-1-yl)-3-phenylpropan-2-ol series of monoamine reuptake inhibitors. | Bioorganic & medicinal chemistry letters 20091001 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. | Bioorganic & medicinal chemistry 20091001 |
1- or 3-(3-Amino-2-hydroxy-1-phenyl propyl)-1,3-dihydro-2H-benzimidazol-2-ones: potent, selective, and orally efficacious norepinephrine reuptake inhibitors. | Journal of medicinal chemistry 20090924 |
Desipramine induces disorder in cholesterol-rich membranes: implications for viral trafficking. | Physical biology 20090910 |
Early prediction of the effectiveness of antidepressants: inputs from an animal model. | Journal of molecular neuroscience : MN 20090901 |
Cooperative opioid and serotonergic mechanisms generate superior antidepressant-like effects in a mice model of depression. | The international journal of neuropsychopharmacology 20090901 |
Discovery of a new series of monoamine reuptake inhibitors, the 1-amino-3-(1H-indol-1-yl)-3-phenylpropan-2-ols. | Bioorganic & medicinal chemistry letters 20090901 |
Neuronal damage and protection in the pathophysiology and treatment of psychiatric illness: stress and depression. | Dialogues in clinical neuroscience 20090901 |
Behavioral effects of four antidepressants on an ischemic rat model of emotional disturbances. | Behavioural brain research 20090812 |
Protracted cannabinoid administration elicits antidepressant behavioral responses in rats: role of gender and noradrenergic transmission. | Physiology & behavior 20090804 |
Treatment with escitalopram but not desipramine decreases escape latency times in a learned helplessness model using juvenile rats. | Psychopharmacology 20090801 |
Side chain flexibilities in the human ether-a-go-go related gene potassium channel (hERG) together with matched-pair binding studies suggest a new binding mode for channel blockers. | Journal of medicinal chemistry 20090723 |
Disposition of desipramine, a sensitive cytochrome P450 2D6 substrate, when coadministered with intravenous temsirolimus. | Cancer chemotherapy and pharmacology 20090701 |
Behavioral sensitization to cocaine: cooperation between glucocorticoids and epinephrine. | Psychopharmacology 20090701 |
Effects of the histone deacetylase inhibitor sodium butyrate in models of depression and anxiety. | Neuropharmacology 20090701 |
Effects of antidepressants on GluR2 Q/R site-RNA editing in modified HeLa cell line. | Neuroscience research 20090701 |
Molecular properties of psychopharmacological drugs determining non-competitive inhibition of 5-HT3A receptors. | European journal of medicinal chemistry 20090601 |
Toluene has antidepressant-like actions in two animal models used for the screening of antidepressant drugs. | Psychopharmacology 20090601 |
Enhanced sensitivity of the MRL/MpJ mouse to the neuroplastic and behavioral effects of chronic antidepressant treatments. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090601 |
Reactivation of inflammatory bowel disease in a mouse model of depression. | Gastroenterology 20090601 |
Jugular venous overflow of noradrenaline from the brain: a neurochemical indicator of cerebrovascular sympathetic nerve activity in humans. | The Journal of physiology 20090601 |
Tacripyrines, the first tacrine-dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer's disease. | Journal of medicinal chemistry 20090514 |
Association of changes in norepinephrine and serotonin transporter expression with the long-term behavioral effects of antidepressant drugs. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090501 |
Strategies for a reliable biostatistical analysis of differentially expressed spots from two-dimensional electrophoresis gels. | Journal of proteome research 20090501 |
3-(Arylamino)-3-phenylpropan-2-olamines as a new series of dual norepinephrine and serotonin reuptake inhibitors. | Bioorganic & medicinal chemistry letters 20090501 |
Melatonin reduces induction of Bax, caspase and cell death in methamphetamine-treated human neuroblastoma SH-SY5Y cultured cells. | Journal of pineal research 20090501 |
Novel sequence variations in the brain-derived neurotrophic factor gene and association with major depression and antidepressant treatment response. | Archives of general psychiatry 20090501 |
Specificity of direct transition from wake to REM sleep in orexin/ataxin-3 transgenic narcoleptic mice. | Experimental neurology 20090501 |
Time-dependent alterations of peripheral immune parameters after nigrostriatal dopamine depletion in a rat model of Parkinson's disease. | Brain, behavior, and immunity 20090501 |
Abstinence following alcohol drinking produces depression-like behavior and reduced hippocampal neurogenesis in mice. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090401 |
Uptake of mIBG and catecholamines in noradrenaline- and organic cation transporter-expressing cells: potential use of corticosterone for a preferred uptake in neuroblastoma- and pheochromocytoma cells. | Nuclear medicine and biology 20090401 |
Will tricyclic antidepressants make a comeback for depressed Parkinson disease patients? | Neurology 20090310 |
Antidepressants influence somatostatin levels and receptor pharmacology in brain. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090301 |
Desipramine modulation of alpha-, gamma-synuclein, and the norepinephrine transporter in an animal model of depression. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090301 |
Postsynaptic alpha-2 adrenergic receptors are critical for the antidepressant-like effects of desipramine on behavior. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090301 |
Desipramine-induced Ca-independent apoptosis in Mg63 human osteosarcoma cells: dependence on P38 mitogen-activated protein kinase-regulated activation of caspase 3. | Clinical and experimental pharmacology & physiology 20090301 |
Remodeling of hippocampal spine synapses in the rat learned helplessness model of depression. | Biological psychiatry 20090301 |
Possible role of norepinephrine in cocaine-induced conditioned taste aversions. | Pharmacology, biochemistry, and behavior 20090301 |
Beta2-adrenoceptors are essential for desipramine, venlafaxine or reboxetine action in neuropathic pain. | Neurobiology of disease 20090301 |
Desipramine reduces stress-activated dynorphin expression and CREB phosphorylation in NAc tissue. | Molecular pharmacology 20090301 |
Reduced in vivo phosphodiesterase-4 response to acute noradrenaline challenge in diet-induced obese rats. | Canadian journal of physiology and pharmacology 20090301 |
The effects of desvenlafaxine and paroxetine on the pharmacokinetics of the cytochrome P450 2D6 substrate desipramine in healthy adults. | Journal of clinical pharmacology 20090201 |
Protective effects of antidepressants against chronic fatigue syndrome-induced behavioral changes and biochemical alterations. | Fundamental & clinical pharmacology 20090201 |
Antidepressants in the treatment of adult attention-deficit hyperactivity disorder: a systematic review. | Advances in therapy 20090201 |
Anti-ceramidase LCL385 acutely reduces BCL-2 expression in the hippocampus but is not associated with an increase of learned helplessness in rats. | Behavioural brain research 20090130 |
Pharmacotherapy and psychotherapy for body dysmorphic disorder. | The Cochrane database of systematic reviews 20090121 |
Protection against cell death and sustained tyrosine hydroxylase phosphorylation in hydrogen peroxide- and MPP-treated human neuroblastoma cells with melatonin. | Journal of pineal research 20090101 |
Inhibition of the norepinephrine transporter improves behavioral flexibility in rats and monkeys. | Psychopharmacology 20090101 |
Antidepressants alleviate the impact of reinforcer downshift. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20090101 |
Expression and functional characterization of choline transporter in human keratinocytes. | Journal of pharmacological sciences 20090101 |
Serotoninergic and non-serotoninergic effects of two tricyclic antidepressants on visceral nociception in a rat model. | Scandinavian journal of gastroenterology 20090101 |
Time course and dose response of alpha tocopherol on oxidative stress in haemodialysis patients. | BMC nephrology 20090101 |
Tetrabenazine as anti-chorea therapy in Huntington disease: an open-label continuation study. Huntington Study Group/TETRA-HD Investigators. | BMC neurology 20090101 |
Alcohol reverses depressive and pronociceptive effects of chronic stress in mice with enhanced activity of the opioid system. | Acta neurobiologiae experimentalis 20090101 |
Age-dependent stimulatory effect of desipramine and fluoxetine pretreatment on metastasis formation by B16F10 melanoma in male C57BL/6 mice. | Pharmacological reports : PR 20090101 |
Potentiation of the antidepressant-like effect of desipramine or reboxetine by metyrapone in the forced swimming test in rats. | Pharmacological reports : PR 20090101 |
Spectroscopic and electrochemical analysis of psychotropic drugs. | Indian journal of pharmaceutical sciences 20090101 |
Comparison of the behavioural pharmacology of the Lister-Hooded with 2 commonly utilised albino rat strains. | Progress in neuro-psychopharmacology & biological psychiatry 20081212 |
Norepinephrine transporter regulation mediates the long-term behavioral effects of the antidepressant desipramine. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20081201 |
Chronic antidepressant treatments increase basic fibroblast growth factor and fibroblast growth factor-binding protein in neurons. | Neuropharmacology 20081201 |
The 5-hydroxytryptamine2A receptor antagonist R-(+)-alpha-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl-4-piperidinemethanol (M100907) attenuates impulsivity after both drug-induced disruption (dizocilpine) and enhancement (antidepressant drugs) of differential-reinforcement-of-low-rate 72-s behavior in the rat. | The Journal of pharmacology and experimental therapeutics 20081201 |
Do desipramine [10,11-dihydro-5-[3-(methylamino) propyl]-5H-dibenz[b,f]azepine monohydrochloride] and fluoxetine [N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]-propan-1-amine] ameliorate the extent of colonic damage induced by acetic acid in rats? | The Journal of pharmacology and experimental therapeutics 20081201 |
Reduction in the latency of action of antidepressants by 17 beta-estradiol in the forced swimming test. | Psychopharmacology 20081201 |
An assessment of drug-drug interactions: the effect of desvenlafaxine and duloxetine on the pharmacokinetics of the CYP2D6 probe desipramine in healthy subjects. | Drug metabolism and disposition: the biological fate of chemicals 20081201 |
Striatal 5-HT1A receptor stimulation reduces D1 receptor-induced dyskinesia and improves movement in the hemiparkinsonian rat. | Neuropharmacology 20081201 |
Synthesis and activity of novel 1- or 3-(3-amino-1-phenyl propyl)-1,3-dihydro-2H-benzimidazol-2-ones as selective norepinephrine reuptake inhibitors. | Bioorganic & medicinal chemistry letters 20081201 |
Reinforcement magnitude modulation of rate-dependent effects of fluvoxamine and desipramine in the rat. | Behavioural pharmacology 20081201 |
Mouse strain differences in the unpredictable chronic mild stress: a four-antidepressant survey. | Behavioural brain research 20081103 |
Differential effects of chronic antidepressant treatment on shuttle box escape deficits induced by uncontrollable stress. | Psychopharmacology 20081101 |
Desipramine blocks alcohol-induced anxiety- and depressive-like behaviors in two rat strains. | Pharmacology, biochemistry, and behavior 20081101 |
Evaluation of the repeated open-space swim model of depression in the mouse. | Pharmacology, biochemistry, and behavior 20081101 |
Effect of desvenlafaxine on the cytochrome P450 2D6 enzyme system. | Journal of psychiatric practice 20081101 |
Possible role of citalopram and desipramine against sleep deprivation-induced anxiety like-behavior alterations and oxidative damage in mice. | Indian journal of experimental biology 20081101 |
Antidepressant-like effects of echo-planar magnetic resonance imaging in mice determined using the forced swimming test. | Brain research 20081021 |
Antidepressant-like behavioral effects of IGF-I produced by enhanced serotonin transmission. | European journal of pharmacology 20081010 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. | Journal of medicinal chemistry 20081009 |
Desipramine potentiation of the acute depressant effects of ethanol: modulation by alpha2-adrenoreceptors and stress. | Neuropharmacology 20081001 |
Desipramine or glutamate antagonists synergized the antidepressant-like actions of intra-nucleus accumbens infusions of minocycline in male Wistar rats. | Progress in neuro-psychopharmacology & biological psychiatry 20081001 |
Synthesis and activity of 1-(3-amino-1-phenylpropyl)indolin-2-ones: a new class of selective norepinephrine reuptake inhibitors. | Bioorganic & medicinal chemistry letters 20080915 |
Chronic unpredictable stress promotes neuronal apoptosis in the cerebral cortex. | Neuroscience letters 20080912 |
Mouse strain differences in immobility and sensitivity to fluvoxamine and desipramine in the forced swimming test: analysis of serotonin and noradrenaline transporter binding. | European journal of pharmacology 20080911 |
Mouse models of Rett syndrome: from behavioural phenotyping to preclinical evaluation of new therapeutic approaches. | Behavioural pharmacology 20080901 |
Animal models of depression in dopamine, serotonin, and norepinephrine transporter knockout mice: prominent effects of dopamine transporter deletions. | Behavioural pharmacology 20080901 |
Neurotoxic catecholamine metabolite in nociceptors contributes to painful peripheral neuropathy. | The European journal of neuroscience 20080901 |
Assessing the neuronal serotonergic target-based antidepressant stratagem: impact of in vivo interaction studies and knockout models. | Current neuropharmacology 20080901 |
Desipramine-induced apoptosis in human PC3 prostate cancer cells: activation of JNK kinase and caspase-3 pathways and a protective role of [Ca2+]i elevation. | Toxicology 20080819 |
Antidepressant treatments regulate matrix metalloproteinases-2 and -9 (MMP-2/MMP-9) and tissue inhibitors of the metalloproteinases (TIMPS 1-4) in the adult rat hippocampus. | Synapse (New York, N.Y.) 20080801 |
Reuptake of L-DOPA-derived extracellular DA in the striatum of a rodent model of Parkinson's disease via norepinephrine transporter. | Synapse (New York, N.Y.) 20080801 |
Phenotypic analysis of GalR2 knockout mice in anxiety- and depression-related behavioral tests. | Neuropeptides 20080801 |
D-161, a novel pyran-based triple monoamine transporter blocker: behavioral pharmacological evidence for antidepressant-like action. | European journal of pharmacology 20080728 |
Discovery of a potent, selective, and less flexible selective norepinephrine reuptake inhibitor (sNRI). | Bioorganic & medicinal chemistry letters 20080715 |
Structure-activity relationships of the cycloalkanol ethylamine scaffold: discovery of selective norepinephrine reuptake inhibitors. | Journal of medicinal chemistry 20080710 |
Toward prediction of alkane/water partition coefficients. | Journal of medicinal chemistry 20080710 |
Enhanced norepinephrine output during long-term desipramine treatment: a possible role for the extraneuronal monoamine transporter (SLC22A3). | Journal of psychiatric research 20080701 |
An in vitro mechanistic study to elucidate the desipramine/bupropion clinical drug-drug interaction. | Drug metabolism and disposition: the biological fate of chemicals 20080701 |
Selective anterograde tracing of nonserotonergic projections from dorsal raphe nucleus to the basal forebrain and extended amygdala. | Journal of chemical neuroanatomy 20080701 |
Pharmacokinetic and pharmacodynamic studies of drug interaction following oral administration of imipramine and sodium alginate in rats. | Naunyn-Schmiedeberg's archives of pharmacology 20080701 |
In vivo PET imaging of cardiac presynaptic sympathoneuronal mechanisms in the rat. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20080701 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). | Journal of medicinal chemistry 20080612 |
Impaired parasympathetic function increases susceptibility to inflammatory bowel disease in a mouse model of depression. | The Journal of clinical investigation 20080602 |
Impaired cannabinoid receptor type 1 signaling interferes with stress-coping behavior in mice. | The pharmacogenomics journal 20080601 |
Inter-individual differences in novelty-seeking behavior in rats predict differential responses to desipramine in the forced swim test. | Psychopharmacology 20080601 |
The effects of chronic versus acute desipramine on nicotine withdrawal and nicotine self-administration in the rat. | Psychopharmacology 20080601 |
Lack of persistent effects of ketamine in rodent models of depression. | Psychopharmacology 20080601 |
Cardiac sympathetic hypo-innervation in familial dysautonomia. | Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20080601 |
Synergistic effects of stress and omega-3 fatty acid deprivation on emotional response and brain lipid composition in adult rats. | Prostaglandins, leukotrienes, and essential fatty acids 20080601 |
Narcolepsy: current treatment options and future approaches. | Neuropsychiatric disease and treatment 20080601 |
Cholecystokinin antagonists (part 1): Antinociceptive, anxiolytic and antidepressant effects of N-(5-methyl-3-oxo-1,2-diphenyl-2,3-dihydro-1H-pyrazol-4-yl)-N'-phenylureas and carboxamides. | Drug discoveries & therapeutics 20080601 |
Increased dopaminergic signaling impairs aversive olfactory memory retention in Drosophila. | Biochemical and biophysical research communications 20080523 |
Differential regulation of central BDNF protein levels by antidepressant and non-antidepressant drug treatments. | Brain research 20080523 |
Antidepressant-like effects of the delta-opioid receptor agonist SNC80 ([(+)-4-[(alphaR)-alpha-[(2S,5R)-2,5-dimethyl-4-(2-propenyl)-1-piperazinyl]-(3-methoxyphenyl)methyl]-N,N-diethylbenzamide) in an olfactory bulbectomized rat model. | Brain research 20080507 |
Determination of fluoxetine in plasma by gas chromatography-mass spectrometry using stir bar sorptive extraction. | Analytica chimica acta 20080505 |
The role of the arginine vasopressin Avp1b receptor in the acute neuroendocrine action of antidepressants. | Psychoneuroendocrinology 20080501 |
Abuse liability assessment of atomoxetine in a drug-abusing population. | Drug and alcohol dependence 20080501 |
Comparison of desipramine and citalopram treatments for depression in Parkinson's disease: a double-blind, randomized, placebo-controlled study. | Movement disorders : official journal of the Movement Disorder Society 20080430 |
The role of NMDA receptor antagonists in nicotine tolerance, sensitization, and physical dependence: a preclinical review. | Yonsei medical journal 20080430 |
Clinical practice. Irritable bowel syndrome. | The New England journal of medicine 20080417 |
Juvenile rats in the forced-swim test model the human response to antidepressant treatment for pediatric depression. | Psychopharmacology 20080401 |
Efficacy of imipramine in psychotic versus nonpsychotic depression. | Journal of clinical psychopharmacology 20080401 |
Biphasic effects of Morus alba leaves green tea extract on mice in chronic forced swimming model. | Phytotherapy research : PTR 20080401 |
Identification of antidepressant drug leads through the evaluation of marine natural products with neuropsychiatric pharmacophores. | Pharmacology, biochemistry, and behavior 20080301 |
VTA dopamine neuron bursting is altered in an animal model of depression and corrected by desipramine. | Journal of molecular neuroscience : MN 20080301 |
MDMA-induced impairment in primates: antagonism by a selective norepinephrine or serotonin, but not by a dopamine/norepinephrine transport inhibitor. | Journal of psychopharmacology (Oxford, England) 20080301 |
Stereotypic behaviour in the deer mouse: pharmacological validation and relevance for obsessive compulsive disorder. | Progress in neuro-psychopharmacology & biological psychiatry 20080215 |
Increased water temperature renders single-housed C57BL/6J mice susceptible to antidepressant treatment in the forced swim test. | Behavioural brain research 20080211 |
An anti-immobility effect of exogenous corticosterone in mice. | European journal of pharmacology 20080202 |
In vitro biotransformation of amitriptyline and imipramine with rat hepatic S9 fraction: evaluation of the toxicity with Spirotox and Thamnotoxkit F Tests. | Archives of environmental contamination and toxicology 20080201 |
The differential regulation of BDNF and TrkB levels in juvenile rats after four days of escitalopram and desipramine treatment. | Neuropharmacology 20080201 |
Noninvasive quantitation of drug concentration in prostate and seminal vesicles: improvement and validation with desipramine and aspirin. | Journal of clinical pharmacology 20080201 |
Antidepressant-like effects of serotonin type-3 antagonist, ondansetron: an investigation in behaviour-based rodent models. | Behavioural pharmacology 20080201 |
Reinforcement magnitude modulates the rate-dependent effects of fluvoxamine and desipramine on fixed-interval responding in the pigeon. | Behavioural pharmacology 20080201 |
Comparison of the effects of desmethylimipramine on behavior in the forced swim test in peripubertal and adult rats. | Behavioural pharmacology 20080201 |
Evaluation of radioiodinated (2S,alphaS)-2-(alpha-(2-iodophenoxy)benzyl)morpholine as a radioligand for imaging of norepinephrine transporter in the heart. | Nuclear medicine and biology 20080201 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. | Journal of medicinal chemistry 20080124 |
Tyrosine depletion lowers dopamine synthesis and desipramine-induced prefrontal cortex catecholamine levels. | Brain research 20080123 |
Photophysics and photochemistry of imipramine, desimipramine, and clomipramine in several solvents: a fluorescence, 266 nm laser flash, and theoretical study. | The journal of physical chemistry. B 20080110 |
Platelet imidazoline receptors as state marker of depressive symptomatology. | Journal of psychiatric research 20080101 |
A novel approach for predicting antidepressant-induced sexual dysfunction in rats. | Psychopharmacology 20080101 |
Oral treatment with desipramine improves breathing and life span in Rett syndrome mouse model. | Respiratory physiology & neurobiology 20080101 |
Estrogens participate in the antidepressant-like effect of desipramine and fluoxetine in male rats. | Pharmacology, biochemistry, and behavior 20080101 |
Antidepressant-like behavioral effects of impaired cannabinoid receptor type 1 signaling coincide with exaggerated corticosterone secretion in mice. | Psychoneuroendocrinology 20080101 |
Down-regulation of norepinephrine transporter expression on membrane surface induced by chronic administration of desipramine and the antagonism by co-administration of local anesthetics in mice. | Neurochemistry international 20080101 |
Desipramine induces apoptotic cell death through nonmitochondrial and mitochondrial pathways in different types of human colon carcinoma cells. | Pharmacology 20080101 |
Automated classification of the behavior of rats in the forced swimming test with support vector machines. | Neural networks : the official journal of the International Neural Network Society 20080101 |
Involvement of ROS/ASMase/JNK signalling pathway in inhibiting UVA-induced apoptosis of HaCaT cells by polypeptide from Chlamys farreri. | Free radical research 20080101 |
Histamine uptake into human vascular endothelial cells and influence of three different antidepressant drugs. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20080101 |
Glucagon-like peptide 1 receptor stimulation reverses key deficits in distinct rodent models of Parkinson's disease. | Journal of neuroinflammation 20080101 |
The role of the entorhinal cortex in extinction: influences of aging. | Neural plasticity 20080101 |
Time-dependent biphasic modulation of human BDNF by antidepressants in neuroblastoma cells. | BMC neuroscience 20080101 |
Alpha-2 adrenergic-induced changes in rectal temperature in adult and 13-day old rats following acute and repeated desipramine administration. | BMC pharmacology 20080101 |
A novel approach to the prediction of drug-drug interactions in humans based on the serum incubation method. | Drug metabolism and pharmacokinetics 20080101 |
Community-based randomised controlled trial evaluating falls and osteoporosis risk management strategies. | Trials 20080101 |
A cost-utility comparison of four first-line medications in painful diabetic neuropathy. | PharmacoEconomics 20080101 |
[Two cases of suspected Munchausen by proxy syndrome: the importance of forensic toxicological analyses in handling suspicions and producing evidence]. | Archiv fur Kriminologie 20080101 |
Pharmacological properties of the active metabolites of the antidepressants desipramine and citalopram. | European journal of pharmacology 20071208 |
The antidepressant desipramine requires the ABCB1 (Mdr1)-type p-glycoprotein to upregulate the glucocorticoid receptor in mice. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20071201 |
Direct inhibitory effect of fluoxetine on N-methyl-D-aspartate receptors in the central nervous system. | Biological psychiatry 20071201 |
Blockade of autoreceptor-mediated inhibition of norepinephrine release by atipamezole is maintained after chronic reuptake inhibition. | The international journal of neuropsychopharmacology 20071201 |
Potential antidepressants: pharmacology of 2-(4-methyl piperazin-1-yl)-1,8-naphthyridine-3-carbonitrile in rodent behavioural models. | Die Pharmazie 20071201 |
[Multivariate study of the Open Field Drink Test using undernourished rats and desipramine as an antipanic drug]. | Investigacion clinica 20071201 |
An antidepressant that extends lifespan in adult Caenorhabditis elegans. | Nature 20071122 |
The guinea pig forced swim test as a new behavioral despair model to characterize potential antidepressants. | Psychopharmacology 20071101 |
Antidepressant-like effect of tramadol in the unpredictable chronic mild stress procedure: possible involvement of the noradrenergic system. | Behavioural pharmacology 20071101 |
Analysis of tricyclic antidepressant drugs in plasma by means of solid-phase microextraction-liquid chromatography-mass spectrometry. | Journal of mass spectrometry : JMS 20071001 |
[Pharmacological treatment of Rett syndrome improves breathing and survival in a mouse model]. | Medecine sciences : M/S 20071001 |
Sensitivity of the five-choice serial reaction time task to the effects of various psychotropic drugs in Sprague-Dawley rats. | Biological psychiatry 20070915 |
LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake. | Science (New York, N.Y.) 20070907 |
Distinct electrophysiological effects of paliperidone and risperidone on the firing activity of rat serotonin and norepinephrine neurons. | Psychopharmacology 20070901 |
[(3)H] citalopram binding to serotonin transporter sites in minnow brains. | Basic & clinical pharmacology & toxicology 20070901 |
Dopamine and depression. | Archives of general psychiatry 20070901 |
Antidepressant-like effect of Cordyceps sinensis in the mouse tail suspension test. | Biological & pharmaceutical bulletin 20070901 |
The effect of beta-cyclodextrin on liquid chromatography/electrospray-mass spectrometry analysis of hydrophobic drug molecules. | Journal of chromatography. A 20070817 |
Reduced evoked fos expression in activity-related brain regions in animal models of behavioral depression. | Progress in neuro-psychopharmacology & biological psychiatry 20070815 |
The effects of serotoninergic, noradrenergic, cholinergic and dopaminergic drugs on vigilance states in MPTP-treated mice. | Brain research 20070803 |
Interstitial norepinephrine concentrations in skeletal muscle of ischemic heart failure. | American journal of physiology. Heart and circulatory physiology 20070801 |
A cost-effectiveness comparison of desipramine, gabapentin, and pregabalin for treating postherpetic neuralgia. | Journal of the American Geriatrics Society 20070801 |
cAMP response element-binding protein deficiency allows for increased neurogenesis and a rapid onset of antidepressant response. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20070718 |
Attenuation of estrous cycle-dependent marble burying in female rats by acute treatment with progesterone and antidepressants. | Psychoneuroendocrinology 20070701 |
Brain Na+, K+-ATPase isoforms: different hypothalamus and mesencephalon response to acute desipramine treatment. | Life sciences 20070627 |
The effects of antidepressants on cyclic AMP-response element-driven gene transcription in a model cell system. | Biochemical pharmacology 20070615 |
chi-Conotoxin and tricyclic antidepressant interactions at the norepinephrine transporter define a new transporter model. | The Journal of biological chemistry 20070615 |
Depletion of serotonin and catecholamines block the acute behavioral response to different classes of antidepressant drugs in the mouse tail suspension test. | Psychopharmacology 20070601 |
Characterization of the antinociceptive actions of bicifadine in models of acute, persistent, and chronic pain. | The Journal of pharmacology and experimental therapeutics 20070601 |
QSAR study on permeability of hydrophobic compounds with artificial membranes. | Bioorganic & medicinal chemistry 20070601 |
Cardiac epinephrine synthesis and ischemia-induced myocardial epinephrine release. | Cardiovascular research 20070601 |
Acidic extracellular pH increases calcium influx-triggered phospholipase D activity along with acidic sphingomyelinase activation to induce matrix metalloproteinase-9 expression in mouse metastatic melanoma. | The FEBS journal 20070601 |
Chronic treatment with desipramine improves cognitive performance of rats in an attentional set-shifting test. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070501 |
Extinction-induced 'despair' in the water maze, exploratory behavior and fear: effects of chronic antidepressant treatment. | Neurobiology of learning and memory 20070501 |
Reduction of high-affinity beta2-adrenergic receptor binding by hyperforin and hyperoside on rat C6 glioblastoma cells measured by fluorescence correlation spectroscopy. | Biochemistry 20070501 |
Desipramine activated Bcl-2 expression and inhibited lipopolysaccharide-induced apoptosis in hippocampus-derived adult neural stem cells. | Journal of pharmacological sciences 20070501 |
Coadministration of nefazodone and desipramine: a pharmacokinetic interaction study. | JPMA. The Journal of the Pakistan Medical Association 20070501 |
Rhesus monkey trace amine-associated receptor 1 signaling: enhancement by monoamine transporters and attenuation by the D2 autoreceptor in vitro. | The Journal of pharmacology and experimental therapeutics 20070401 |
Desipramine-induced Ca2+ movement and cytotoxicity in PC3 human prostate cancer cells. | Toxicology in vitro : an international journal published in association with BIBRA 20070401 |
Efficacy of noradrenergic and serotonergic antidepressants in chronic back pain: a preliminary concentration-controlled trial. | Journal of clinical psychopharmacology 20070401 |
Treatment with desipramine improves breathing and survival in a mouse model for Rett syndrome. | The European journal of neuroscience 20070401 |
Noradrenergic facilitation of shock-probe defensive burying in lateral septum of rats, and modulation by chronic treatment with desipramine. | Progress in neuro-psychopharmacology & biological psychiatry 20070330 |
Localization of cocaine analog [125I]RTI 82 irreversible binding to transmembrane domain 6 of the dopamine transporter. | The Journal of biological chemistry 20070323 |
Abnormal involuntary movements (AIMs) following pulsatile dopaminergic stimulation: severe deterioration and morphological correlates following the loss of locus coeruleus neurons. | Brain research 20070302 |
Sympathetic and hyperthermic reactions by orexin A: role of cerebral catecholaminergic neurons. | Regulatory peptides 20070301 |
Pharmacological characterization of the beta-adrenoceptor that mediates the relaxant response to noradrenaline in guinea-pig tracheal smooth muscle. | Naunyn-Schmiedeberg's archives of pharmacology 20070301 |
Calcineurin (protein phosphatase 2B) is involved in the mechanisms of action of antidepressants. | Neuroscience 20070223 |
Neuronal proteins involved in synaptic targeting of AMPA receptors in rat hippocampus by antidepressant drugs. | Biochemical and biophysical research communications 20070216 |
Sphingosine-1-phosphate protects proliferating endothelial cells from ceramide-induced apoptosis but not from DNA damage-induced mitotic death. | Cancer research 20070215 |
Pharmacokinetics of desipramine HCl when administered with cinacalcet HCl. | European journal of clinical pharmacology 20070201 |
Effects of different doses of venlafaxine on serotonin and norepinephrine reuptake in healthy volunteers. | The international journal of neuropsychopharmacology 20070201 |
Effect of antidepressant drugs on 6-OHDA-treated mice in the FST. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20070201 |
The role of noradrenergic tone in the dorsal raphe nucleus of the mouse in the acute behavioral effects of antidepressant drugs. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20070201 |
Role of atypical opiates in OCD. Experimental approach through the study of 5-HT(2A/C) receptor-mediated behavior. | Psychopharmacology 20070201 |
Suicidality scores during double-blind fluoxetine and desipramine treatment in Mexican Americans. | Journal of clinical psychopharmacology 20070201 |
Disruption of noradrenergic transmission and the behavioural response to a novel environment in NK1R-/- mice. | The European journal of neuroscience 20070201 |
Effects of acute fluoxetine, paroxetine and desipramine on rats tested on the elevated plus-maze. | Behavioural brain research 20070125 |
Enhancement of the anti-immobility action of antidepressants by a selective 5-HT7 receptor antagonist in the forced swimming test in mice. | European journal of pharmacology 20070119 |
Effect of chronic administration of duloxetine on serotonin and norepinephrine transporter binding sites in rat brain. | Biological psychiatry 20070115 |
Synthesis of 11C-labelled (R)-OHDMI and CFMME and their evaluation as candidate radioligands for imaging central norepinephrine transporters with PET. | Bioorganic & medicinal chemistry 20070115 |
Antidepressant-induced undesirable weight gain: prevention with rimonabant without interference with behavioral effectiveness. | European journal of pharmacology 20070112 |
Vulnerability for apoptosis in the limbic system after myocardial infarction in rats: a possible model for human postinfarct major depression. | Journal of psychiatry & neuroscience : JPN 20070101 |
Anti-inflammatory properties of desipramine and fluoxetine. | Respiratory research 20070101 |
CRE/CREB-driven up-regulation of gene expression by chronic social stress in CRE-luciferase transgenic mice: reversal by antidepressant treatment. | PloS one 20070101 |
A possible role for the endocannabinoid system in the neurobiology of depression. | Clinical practice and epidemiology in mental health : CP & EMH 20070101 |
Effect of citalopram in the modified forced swim test in rats. | Pharmacological reports : PR 20070101 |
Nocturnal enuresis. | BMJ clinical evidence 20070101 |
Functional interaction between alpha2-adrenoceptors, mu- and kappa-opioid receptors in the guinea pig myenteric plexus: effect of chronic desipramine treatment. | European journal of pharmacology 20061228 |
Involvement of the endocannabinoid system in the ability of long-term tricyclic antidepressant treatment to suppress stress-induced activation of the hypothalamic-pituitary-adrenal axis. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20061201 |
The mechanism of activity-dependent sodium channel inhibition by the antidepressants fluoxetine and desipramine. | Molecular pharmacology 20061201 |
Analgesic effects of serotonergic, noradrenergic or dual reuptake inhibitors in the carrageenan test in rats: evidence for synergism between serotonergic and noradrenergic reuptake inhibition. | Neuropharmacology 20061201 |
Delayed effects of antidepressant drugs in rats. | Behavioural pharmacology 20061201 |
Resolving the onset of antidepressants' clinical actions: critical for clinical practice and new drug development. | Journal of clinical psychopharmacology 20061201 |
Involvement of sphingolipids in apoptin-induced cell killing. | Molecular therapy : the journal of the American Society of Gene Therapy 20061101 |
Desipramine prevents the sustained increase in corticotropin-releasing hormone-like immunoreactivity induced by repeated immobilization stress in the rat central extended amygdala. | Journal of neuroscience research 20061101 |
Inhibition of nonexocytotic norepinephrine release by desipramine reduces myocardial infarction size. | Canadian journal of physiology and pharmacology 20061101 |
Antidepressant treatment reduces Fos-like immunoreactivity induced by swim stress in different columns of the periaqueductal gray matter. | Brain research bulletin 20061016 |
The effects of alpha1-acid glycoprotein on the reversal of chloroquine resistance in Plasmodium falciparum. | Annals of tropical medicine and parasitology 20061001 |
Ang II and Ang III modulate PTZ seizure threshold in non-stressed and stressed mice: possible involvement of noradrenergic mechanism. | Neuropeptides 20061001 |
Effects of pregnanolone in rats discriminating cocaine. | Pharmacology, biochemistry, and behavior 20061001 |
The comparison of immobility time in experimental rat swimming models. | Life sciences 20060927 |
Antidepressant-like activity of selective serotonin reuptake inhibitors combined with a NK1 receptor antagonist in the mouse forced swimming test. | Behavioural brain research 20060925 |
Inhibition of N-methyl-D-aspartate receptor function appears to be one of the common actions for antidepressants. | Journal of psychopharmacology (Oxford, England) 20060901 |
Optimization of solid-phase microextraction procedures for the determination of tricyclic antidepressants and anticonvulsants in plasma samples by liquid chromatography. | Analytical and bioanalytical chemistry 20060901 |
Ceramide is the key mediator of oxidative stress-induced apoptosis in retinal photoreceptor cells. | Journal of neurochemistry 20060901 |
Desipramine inhibits Na+/H+ exchanger in human submandibular cells. | Journal of dental research 20060901 |
Pharmacological and genetic influences on hole-board behaviors in mice. | Pharmacology, biochemistry, and behavior 20060901 |
Antidepressant principles of the roots of Polygala tenuifolia. | Journal of natural products 20060901 |
Antidepressant-like and anxiolytic-like actions of the mGlu5 receptor antagonist MTEP, microinjected into lateral septal nuclei of male Wistar rats. | Progress in neuro-psychopharmacology & biological psychiatry 20060830 |
Biphasic change in BDNF gene expression following antidepressant drug treatment explained by differential transcript regulation. | Brain research 20060823 |
New insights on the use of desipramine as an inhibitor for acid ceramidase. | FEBS letters 20060821 |
Effects of acute and subchronic treatments with fluoxetine and desipramine on the memory of fear in moderate and high-intensity contextual conditioning. | European journal of pharmacology 20060807 |
Nigrostriatal damage with 6-OHDA: validation of routinely applied procedures. | Annals of the New York Academy of Sciences 20060801 |
Characterization of cytotoxic actions of tricyclic antidepressants on human HT29 colon carcinoma cells. | European journal of pharmacology 20060710 |
Critical involvement of dopaminergic neurotransmission in impulsive decision making. | Biological psychiatry 20060701 |
Behavioral disinhibition requires dopamine receptor activation. | Psychopharmacology 20060701 |
Monoamine uptake inhibitors block alpha7-nAChR-mediated cerebral nitrergic neurogenic vasodilation. | American journal of physiology. Heart and circulatory physiology 20060701 |
Brugada electrocardiographic pattern due to tricyclic antidepressant overdose. | Journal of electrocardiology 20060701 |
Differential alpha-mediated inhibition of dopamine and noradrenaline release in the parietal and occipital cortex following noradrenaline transporter blockade. | Journal of neurochemistry 20060701 |
Hippocampal cell proliferation regulation by repeated stress and antidepressants. | Neuroreport 20060626 |
Down-regulation of norepinephrine transporter function induced by chronic administration of desipramine linking to the alteration of sensitivity of local-anesthetics-induced convulsions and the counteraction by co-administration with local anesthetics. | Brain research 20060622 |
Frequency of high-risk use of QT-prolonging medications. | Pharmacoepidemiology and drug safety 20060601 |
Pharmacological treatment of attention-deficit/hyperactivity disorder in adults. | Expert opinion on investigational drugs 20060601 |
[Trazodone for the treatment of behavioral and psychological symptoms of dementia (BPSD) in Alzheimer's disease: a retrospective study focused on the aggression and negativism in caregiving situations]. | No to shinkei = Brain and nerve 20060601 |
Post-stress facilitation of serotonergic, but not noradrenergic, neurotransmission in the dorsal hippocampus prevents learned helplessness development in rats. | Brain research 20060504 |
Anandamide-induced apoptosis in Chang liver cells involves ceramide and JNK/AP-1 pathway. | International journal of molecular medicine 20060501 |
The involvement of norepinephrine and microglia in hypothalamic and splenic IL-1beta responses to stress. | Journal of neuroimmunology 20060401 |
Rates of in vivo methylation of desipramine and nortriptyline. | Pharmacotherapy 20060401 |
The involvement of endogenous opioid mechanisms in the antinociceptive effects induced by antidepressant drugs, desipramine and trimipramine. | Pharmacology, biochemistry, and behavior 20060401 |
A comparison of the chronic treatment effects of venlafaxine and other antidepressants on serotonin and norepinephrine transporters. | Biological psychiatry 20060301 |
Cardiac sympathetic neuroprotective effect of desipramine in tachycardia-induced cardiomyopathy. | American journal of physiology. Heart and circulatory physiology 20060301 |
Effects of venlafaxine and desipramine on heroin-induced conditioned place preference in the rat. | Addiction biology 20060301 |
Social isolation alters the effect of desipramine in the rat forced swimming test. | Behavioural brain research 20060227 |
Chronic antidepressant treatment modulates the release of somatostatin in the rat nucleus accumbens. | Neuroscience letters 20060227 |
Saw palmetto is an indirectly acting sympathomimetic in the rat-isolated prostate gland. | The Prostate 20060201 |
G protein-activated inwardly rectifying K+ channel inhibition and rescue of weaver mouse motor functions by antidepressants. | Neuroscience research 20060201 |
Response to SSRI-induced enuresis: a case report. | Journal of clinical psychopharmacology 20060201 |
Nonstimulant medications for the treatment of ADHD. | Journal of child and adolescent psychiatric nursing : official publication of the Association of Child and Adolescent Psychiatric Nurses, Inc 20060201 |
Prediction of drug-drug interactions for AUCoral of high clearance drug from in vitro data: utilization of a microtiter plate assay and a dispersion model. | Current drug metabolism 20060201 |
Dopamine efflux in the rat striatum evoked by electrical stimulation of the subthalamic nucleus: potential mechanism of action in Parkinson's disease. | The European journal of neuroscience 20060201 |
A double-blind, multicenter, parallel-group study of paroxetine, desipramine, or placebo in breast cancer patients (stages I, II, III, and IV) with major depression. | The Journal of clinical psychiatry 20060201 |
Direct involvement of orexinergic systems in the activation of the mesolimbic dopamine pathway and related behaviors induced by morphine. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20060111 |
Enhanced neurally evoked responses and inhibition of norepinephrine reuptake in rat mesenteric arteries after spinal transection. | American journal of physiology. Heart and circulatory physiology 20060101 |
Evidence that serotonin reuptake modulators increase the density of serotonin innervation in the forebrain. | Journal of neurochemistry 20060101 |
Desipramine attenuates working memory impairments induced by partial loss of catecholamines in the rat medial prefrontal cortex. | Psychopharmacology 20060101 |
Synthesis and positron emission tomography evaluation of three norepinephrine transporter radioligands: [C-11]desipramine, [C-11]talopram and [C-11]talsupram. | Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20060101 |
Excess fatality from desipramine in children and adolescents. | Journal of the American Academy of Child and Adolescent Psychiatry 20060101 |
Antidepressants reverse corticosterone-mediated decrease in brain-derived neurotrophic factor expression: differential regulation of specific exons by antidepressants and corticosterone. | Neuroscience 20060101 |
Effect of MPEP treatment on brain-derived neurotrophic factor gene expression. | Pharmacological reports : PR 20060101 |
Pharmacological enhancement of cannabinoid CB1 receptor activity elicits an antidepressant-like response in the rat forced swim test. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20051201 |
Sequential changes in BDNF mRNA expression and synaptic levels of AMPA receptor subunits in rat hippocampus after chronic antidepressant treatment. | Neuropharmacology 20051201 |
The human norepinephrine transporter in combination with 11C-m-hydroxyephedrine as a reporter gene/reporter probe for PET of gene therapy. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20051201 |
Effect of low-dose ritonavir (100 mg twice daily) on the activity of cytochrome P450 2D6 in healthy volunteers. | Clinical pharmacology and therapeutics 20051201 |
Antidepressants and prolonged stress in rats modulate CAM-L1, laminin, and pCREB, implicated in neuronal plasticity. | Neurobiology of disease 20051101 |
Desipramine treatment of cocaine-dependent patients with depression: a placebo-controlled trial. | Drug and alcohol dependence 20051101 |
Interaction of organic cations with a newly identified plasma membrane monoamine transporter. | Molecular pharmacology 20051101 |
Selective cortical VGLUT1 increase as a marker for antidepressant activity. | Neuropharmacology 20051101 |
Effect of prolonged exposure to milnacipran on norepinephrine transporter in cultured bovine adrenal medullary cells. | Biochemical pharmacology 20051101 |
Fluvoxamine and desipramine on fixed-ratio responding: effects of reinforcement magnitude. | Behavioural pharmacology 20051101 |
Chronic administration of the delta opioid receptor agonist (+)BW373U86 and antidepressants on behavior in the forced swim test and BDNF mRNA expression in rats. | Psychopharmacology 20051101 |
Cardiac and extracardiac sympathetic denervation in Parkinson's disease with orthostatic hypotension and in pure autonomic failure. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20051101 |
Treatment response in antidepressant-naïve postherpetic neuralgia patients: double-blind, randomized trial. | The journal of pain : official journal of the American Pain Society 20051101 |
Antidepressants and REM sleep in Wistar-Kyoto and Sprague-Dawley rats. | European journal of pharmacology 20051017 |
A selective test for antidepressant treatments using rats bred for stress-induced reduction of motor activity in the swim test. | Psychopharmacology 20051001 |
Role of increased sphingomyelinase activity in apoptosis and organ failure of patients with severe sepsis. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20051001 |
Post-mortem human brain autoradiography of the norepinephrine transporter using (S,S)-[18F]FMeNER-D2. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20051001 |
Effects of zotepine and olanzapine on noradrenaline transporter in cultured bovine adrenal medullary cells. | Human psychopharmacology 20051001 |
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity. | Current drug metabolism 20051001 |
Antidepressants differentially affect expression of complexin I and II RNA in rat hippocampus. | Psychopharmacology 20050901 |
The effects of desmethylimipramine on cyclic AMP-stimulated gene transcription in a model cell system. | Biochemical pharmacology 20050901 |
Tyrosine administration does not affect desipramine-induced dopamine levels as measured in vivo in prefrontal cortex. | Brain research 20050830 |
Evidence for increased expression of the vesicular glutamate transporter, VGLUT1, by a course of antidepressant treatment. | Journal of neurochemistry 20050801 |
Cocaine-induced modulation of long-term potentiation in the CA1 region of rat hippocampus. | Neuropharmacology 20050801 |
Ethanol-induced changes in the content of triglycerides, ceramides, and glucosylceramides in cultured neurons. | Alcoholism, clinical and experimental research 20050801 |
Deliberate misuse of tricyclic antidepressants by intravenous drug users--case studies and report. | Scottish medical journal 20050801 |
An index of local sensitivity to nonignorable drop-out in longitudinal modelling. | Statistics in medicine 20050730 |
Linking tricyclic antidepressants to ionotropic glutamate receptors. | Biochemical and biophysical research communications 20050729 |
Effect of desipramine on Ca2+ levels and growth in renal tubular cells. | Cellular signalling 20050701 |
Antidepressant action of agomelatine (S 20098) in a transgenic mouse model. | Progress in neuro-psychopharmacology & biological psychiatry 20050701 |
Therapeutic monitoring of imipramine and desipramine by micellar liquid chromatography with direct injection and electrochemical detection. | Biomedical chromatography : BMC 20050601 |
Interferon-alpha-induced modulation of glucocorticoid and serotonin receptors as a mechanism of depression. | Journal of hepatology 20050601 |
Regulation of activin mRNA and Smad2 phosphorylation by antidepressant treatment in the rat brain: effects in behavioral models. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20050518 |
Discovery of novel conformationally constrained tropane-based biaryl and arylacetylene ligands as potent and selective norepinephrine transporter inhibitors and potential antidepressants. | Bioorganic & medicinal chemistry letters 20050516 |
Reinforced spatial alternation as an animal model of obsessive-compulsive disorder (OCD): investigation of 5-HT2C and 5-HT1D receptor involvement in OCD pathophysiology. | Biological psychiatry 20050515 |
Effects of desipramine and tramadol in a chronic mild stress model in mice are altered by yohimbine but not by pindolol. | European journal of pharmacology 20050509 |
Behavioral responses during the forced swim test are not affected by anti-inflammatory agents or acute illness induced by lipopolysaccharide. | Behavioural brain research 20050507 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). | Journal of medicinal chemistry 20050505 |
Aging and cardiac responses to epinephrine in humans: role of neuronal uptake. | American journal of physiology. Heart and circulatory physiology 20050501 |
Brugada syndrome precipitated by a tricyclic antidepressant. | Heart (British Cardiac Society) 20050501 |
Norepinephrine transporter function and desipramine: residual drug effects versus short-term regulation. | Journal of neuroscience methods 20050430 |
Variability of the mesolimbic neuronal activity in a rat model of depression. | Neuroreport 20050404 |
Evaluation of the reinforcing effects of monoamine reuptake inhibitors under a concurrent schedule of food and i.v. drug delivery in rhesus monkeys. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050401 |
Reboxetine for the treatment of patients with Cocaine Dependence Disorder. | Human psychopharmacology 20050401 |
Different effects of desipramine on bufuralol 1''-hydroxylation by rat and human CYP2D enzymes. | Biological & pharmaceutical bulletin 20050401 |
Cognitive therapy vs medications in the treatment of moderate to severe depression. | Archives of general psychiatry 20050401 |
A comparison of neurokinin 1 receptor knock-out (NK1-/-) and wildtype mice: exploratory behaviour and extracellular noradrenaline concentration in the cerebral cortex of anaesthetised subjects. | Neuropharmacology 20050401 |
Antidepressant-like effects of cranial stimulation within a low-energy magnetic field in rats. | Biological psychiatry 20050315 |
Coadministration of histone deacetylase inhibitors and perifosine synergistically induces apoptosis in human leukemia cells through Akt and ERK1/2 inactivation and the generation of ceramide and reactive oxygen species. | Cancer research 20050315 |
Obesity among outpatients with major depressive disorder. | The international journal of neuropsychopharmacology 20050301 |
Phenotypic assessment of galanin overexpressing and galanin receptor R1 knockout mice in the tail suspension test for depression-related behavior. | Psychopharmacology 20050301 |
The safety of non-stimulant agents for the treatment of attention-deficit hyperactivity disorder. | Expert opinion on drug safety 20050301 |
Protection of LLC-PK1 cells against hydrogen peroxide-induced cell death by modulation of ceramide level. | Archives of pharmacal research 20050301 |
Effects of desipramine treatment on tyrosine hydroxylase gene expression in cultured neuroblastoma cells and rat brain tissue. | Brain research. Molecular brain research 20050218 |
Comparative effects of duloxetine and desipramine on sleep EEG in healthy subjects. | Psychopharmacology 20050201 |
Effects of acute treatment with antidepressant drugs on sensorimotor gating deficits in rats. | Psychopharmacology 20050201 |
Effects of repeated cocaine on the release and clearance of dopamine within the rat medial prefrontal cortex. | Synapse (New York, N.Y.) 20050201 |
Blood pressure changes associated with medication treatment of adults with attention-deficit/hyperactivity disorder. | The Journal of clinical psychiatry 20050201 |
Quantitative in vitro phosphor imaging using [3H] and [18F] radioligands: the effects of chronic desipramine treatment on serotonin 5-HT2 receptors. | Journal of neuroscience methods 20050130 |
GABAB receptor antagonist-mediated antidepressant-like behavior is serotonin-dependent. | The Journal of pharmacology and experimental therapeutics 20050101 |
Antidepressants attenuate both the enhanced ethanol intake and ethanol-induced anxiolytic effects in diazepam withdrawn rats. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20050101 |
Hyperfunctionality of serotonin-2C receptor-mediated inhibition of accumbal dopamine release in an animal model of depression is reversed by antidepressant treatment. | Neuropharmacology 20050101 |
Amygdala-dependent mechanisms underlying memory retrieval of conditioned taste aversion. | Chemical senses 20050101 |
Chronic treatment with clomipramine and desipramine induces deficit in long-term visuo-spatial memory of rats. | The International journal of neuroscience 20050101 |
Desipramine treatment for cocaine dependence in buprenorphine- or methadone-treated patients: baseline urine results as predictor of response. | The American journal on addictions 20050101 |
An antidepressant mechanism of desipramine is to decrease tumor necrosis factor-alpha production culminating in increases in noradrenergic neurotransmission. | Neuroscience 20050101 |
Effect of long-lasting serotonin depletion on environmental enrichment-induced neurogenesis in adult rat hippocampus and spatial learning. | Neuroscience 20050101 |
Effects of desipramine and escitalopram on postprandial symptoms induced by the nutrient drink test in healthy volunteers: a randomized, double-blind, placebo-controlled study. | Digestion 20050101 |
Voltammetric assessment of dopamine clearance in the absence of the dopamine transporter: no contribution of other transporters in core or shell of nucleus accumbens. | Journal of neuroscience methods 20041230 |
Association of a corticotropin-releasing hormone receptor 1 haplotype and antidepressant treatment response in Mexican-Americans. | Molecular psychiatry 20041201 |
Chronic treatment with desipramine and fluoxetine modulate BDNF, CaMKKalpha and CaMKKbeta mRNA levels in the hippocampus of transgenic mice expressing antisense RNA against the glucocorticoid receptor. | Neuropharmacology 20041201 |
5,7-dihydroxytryptamine lesions of the dorsal and median raphe nuclei interfere with lithium-induced conditioned gaping, but not conditioned taste avoidance, in rats. | Behavioral neuroscience 20041201 |
Effects of chronic stress on methamphetamine-induced dopamine depletions in the striatum. | Annals of the New York Academy of Sciences 20041201 |
Depressive symptoms and alcohol consumption among nonalcoholic depression patients treated with desipramine. | Canadian journal of psychiatry. Revue canadienne de psychiatrie 20041201 |
Evaluation of fresh and cryopreserved hepatocytes as in vitro drug metabolism tools for the prediction of metabolic clearance. | Drug metabolism and disposition: the biological fate of chemicals 20041101 |
Autoreceptor-mediated inhibition of norepinephrine release in rat medial prefrontal cortex is maintained after chronic desipramine treatment. | Journal of neurochemistry 20041101 |
Beta-arrestin-1 levels: reduced in leukocytes of patients with depression and elevated by antidepressants in rat brain. | The American journal of psychiatry 20041101 |
Nogo-66 receptor prevents raphespinal and rubrospinal axon regeneration and limits functional recovery from spinal cord injury. | Neuron 20041028 |
Antidepressants activate CaMKII in neuron cell body by Thr286 phosphorylation. | Neuroreport 20041025 |
The effect of escitalopram, desipramine, electroconvulsive seizures and lithium on brain-derived neurotrophic factor mRNA and protein expression in the rat brain and the correlation to 5-HT and 5-HIAA levels. | Brain research 20041022 |
Effect of antidepressants on GABA(B) receptor function and subunit expression in rat hippocampus. | Biochemical pharmacology 20041015 |
Inhibition of G protein-activated inwardly rectifying K+ channels by various antidepressant drugs. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20041001 |
Psychosocial functioning during the treatment of major depressive disorder with fluoxetine. | Journal of clinical psychopharmacology 20041001 |
Excess fatality from desipramine and dosage recommendations. | Therapeutic drug monitoring 20041001 |
Antidepressant-like activity of corticotropin-releasing factor type-1 receptor antagonists in mice. | European journal of pharmacology 20040919 |
Evaluation of the reinforcing effects of atomoxetine in monkeys: comparison to methylphenidate and desipramine. | Drug and alcohol dependence 20040906 |
Antidepressant-like effects of a novel pentapeptide, nemifitide, in an animal model of depression. | Psychopharmacology 20040901 |
Brain-derived tumor necrosis factor-alpha and its involvement in noradrenergic neuron functioning involved in the mechanism of action of an antidepressant. | The Journal of pharmacology and experimental therapeutics 20040901 |
Chronic antidepressant treatment causes a selective reduction of mu-opioid receptor binding and functional coupling to G Proteins in the amygdala of fawn-hooded rats. | The Journal of pharmacology and experimental therapeutics 20040901 |
Reduction of vascular noradrenaline sensitivity by AT1 antagonists depends on functional sympathetic innervation. | Hypertension (Dallas, Tex. : 1979) 20040901 |
Gangliosides link the acidic sphingomyelinase-mediated induction of ceramide to 12-lipoxygenase-dependent apoptosis of neuroblastoma in response to fenretinide. | Journal of the National Cancer Institute 20040901 |
Antidepressant-like effect of tramadol and its enantiomers in reserpinized mice: comparative study with desipramine, fluvoxamine, venlafaxine and opiates. | Journal of psychopharmacology (Oxford, England) 20040901 |
Antidepressant-like effects of CRF1 receptor antagonist SSR125543 in an animal model of depression. | European journal of pharmacology 20040816 |
The cytoprotective effect of inulin-type hexasaccharide extracted from Morinda officinalis on PC12 cells against the lesion induced by corticosterone. | Life sciences 20040813 |
27-Hydroxycholesterol inhibits neutral sphingomyelinase in cultured human endothelial cells. | Life sciences 20040813 |
Ceramide triggers Weibel-Palade body exocytosis. | Circulation research 20040806 |
Antianxiety and antidepressant-like effects of AC-5216, a novel mitochondrial benzodiazepine receptor ligand. | British journal of pharmacology 20040801 |
The induction of splenic suppressor T cells through an immune-privileged site requires an intact sympathetic nervous system. | Journal of neuroimmunology 20040801 |
Testosterone-dependent antidepressant-like effect of noradrenergic but not of serotonergic drugs. | Pharmacology, biochemistry, and behavior 20040801 |
Serum folate, vitamin B12, and homocysteine in major depressive disorder, Part 1: predictors of clinical response in fluoxetine-resistant depression. | The Journal of clinical psychiatry 20040801 |
Modulating sensorimotor gating in healthy volunteers: the effects of desipramine and haloperidol. | Psychiatry research 20040715 |
Differential interactions of desipramine with amphetamine and methamphetamine: evidence that amphetamine releases dopamine from noradrenergic neurons in the medial prefrontal cortex. | Neurochemical research 20040701 |
Microautoradiography of [123I]ADAM in mice treated with fluoxetine and serotonin reuptake inhibitors. | Nuclear medicine and biology 20040701 |
Effects of neuronal norepinephrine uptake blockade on baroreflex neural and peripheral arc transfer characteristics. | American journal of physiology. Regulatory, integrative and comparative physiology 20040601 |
Total sleep deprivation decreases immobility in the forced-swim test. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040601 |
Clinical implications of genetic polymorphism of CYP2D6 in Mexican Americans. | Annals of internal medicine 20040601 |
Neuropharmacological treatment of refractory idiopathic thrombocytopenic purpura: roles of circulating catecholamines and serotonin. | Thrombosis and haemostasis 20040601 |
Involvement of ceramide in the mechanism of Cr(VI)-induced apoptosis of CHO cells. | Free radical research 20040601 |
Cellular consequences of stress and depression. | Dialogues in clinical neuroscience 20040601 |
Norepinephrine-deficient mice lack responses to antidepressant drugs, including selective serotonin reuptake inhibitors. | Proceedings of the National Academy of Sciences of the United States of America 20040525 |
Probing the mechanism of drug/lipid membrane interactions using Biacore. | Analytical biochemistry 20040515 |
Serotonin reuptake inhibitors do not prevent 5,7-dihydroxytryptamine-induced depletion of serotonin in rat brain. | Brain research 20040508 |
Comparative study of the effects of desipramine and reboxetine on locus coeruleus neurons in rat brain slices. | Neuropharmacology 20040501 |
NO induced apoptosis of vascular smooth muscle cells accompanied by ceramide increase. | Journal of cellular physiology 20040501 |
Role of ceramide in ischemic preconditioning. | Journal of the American College of Surgeons 20040501 |
PAMPA--a drug absorption in vitro model 8. Apparent filter porosity and the unstirred water layer. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20040501 |
Toward a rapidly acting antidepressant: the normetanephrine and extraneuronal monoamine transporter (uptake 2) hypothesis. | The American journal of psychiatry 20040501 |
'Compulsive' lever-pressing in rats is attenuated by the serotonin re-uptake inhibitors paroxetine and fluvoxamine but not by the tricyclic antidepressant desipramine or the anxiolytic diazepam. | Behavioural pharmacology 20040501 |
Inhibition of cytochrome P450 enzymes participating in p-nitrophenol hydroxylation by drugs known as CYP2E1 inhibitors. | Chemico-biological interactions 20040415 |
The delta-opioid receptor agonist (+)BW373U86 regulates BDNF mRNA expression in rats. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040401 |
Addictive and non-addictive drugs induce distinct and specific patterns of ERK activation in mouse brain. | The European journal of neuroscience 20040401 |
[Effects of neurotensin microinjected into ventral tegmental area on spontaneous motor activity in neonatal 6-hydroxydopamine-treated rats]. | Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20040401 |
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies. | Biochemical and biophysical research communications 20040319 |
Enzymatic tissue digestion as an alternative sample preparation approach for quantitative analysis using liquid chromatography-tandem mass spectrometry. | Analytical chemistry 20040315 |
Mirtazapine-induced corelease of dopamine and noradrenaline from noradrenergic neurons in the medial prefrontal and occipital cortex. | European journal of pharmacology 20040308 |
Effect of combined administration of 5-HT1A or 5-HT1B/1D receptor antagonists and antidepressants in the forced swimming test. | European journal of pharmacology 20040308 |
Onset and early behavioral effects of pharmacologically different antidepressants and placebo in depression. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040301 |
Role of histamine H3 receptors during ischemia/reperfusion in isolated rat hearts. | Journal of cardiovascular pharmacology 20040301 |
Different prejunctional and postjunctional responses to angiotensin II and AT1-receptor inhibition: influence of maturation. | Journal of cardiovascular pharmacology 20040301 |
Inducible cAMP early repressor regulates corticosterone suppression after tricyclic antidepressant treatment. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20040225 |
Relationship between the antinociceptive response to desipramine and changes in GABAB receptor function and subunit expression in the dorsal horn of the rat spinal cord. | Biochemical pharmacology 20040215 |
Interactions of acid sphingomyelinase and lipid bilayers in the presence of the tricyclic antidepressant desipramine. | FEBS letters 20040213 |
Sympathetic augmentation in hypertension: role of nerve firing, norepinephrine reuptake, and Angiotensin neuromodulation. | Hypertension (Dallas, Tex. : 1979) 20040201 |
Effect of the novel anxiolytic drug deramciclane on cytochrome P(450) 2D6 activity as measured by desipramine pharmacokinetics. | European journal of clinical pharmacology 20040201 |
Combining norepinephrine and serotonin reuptake inhibition mechanisms for treatment of depression: a double-blind, randomized study. | Biological psychiatry 20040201 |
Regulation of the norepinephrine transporter by chronic administration of antidepressants. | Biological psychiatry 20040201 |
Effects of antidepressants on the conformation of phospholipid headgroups studied by solid-state NMR. | Magnetic resonance in chemistry : MRC 20040201 |
Antidepressant-like effect of nicotinamide adenine dinucleotide in the forced swim test in rats. | Pharmacology, biochemistry, and behavior 20040201 |
Noradrenaline transporter blockers raise extracellular dopamine in medial prefrontal but not parietal and occipital cortex: differences with mianserin and clozapine. | Journal of neurochemistry 20040201 |
Alpha-tocopherol influences the lipid membrane affinity of desipramine in a pH-dependent manner. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20040201 |
Ethnic differences in substance abuse treatment retention, compliance, and outcome from two clinical trials. | Psychiatric services (Washington, D.C.) 20040201 |
The persistent membrane retention of desipramine causes lasting inhibition of norepinephrine transporter function. | Neurochemical research 20040201 |
Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes. | Cell 20040109 |
Dopamine in the medial prefrontal cortex controls genotype-dependent effects of amphetamine on mesoaccumbens dopamine release and locomotion. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040101 |
Modification by dopaminergic drugs of choice behavior under concurrent schedules of intravenous saline and food delivery in monkeys. | The Journal of pharmacology and experimental therapeutics 20040101 |
The serotonin-dopamine interaction is critical for fast-onset action of antidepressant treatment: in vivo studies in an animal model of depression. | Progress in neuro-psychopharmacology & biological psychiatry 20040101 |
Potential and practical adrenomedullary PET radiopharmaceuticals as an alternative to m-iodobenzylguanidine: m-(omega-[18F]fluoroalkyl)benzylguanidines. | Bioconjugate chemistry 20040101 |
Depression predicts higher rates of heroin use on desipramine with buprenorphine than with methadone. | The American journal on addictions 20040101 |
Influence of antidepressant drugs on macrophage cytotoxic activity in rats. | Polish journal of pharmacology 20040101 |
Evidence that the metabotropic glutamate receptor 5 antagonist MPEP may act as an inhibitor of the norepinephrine transporter in vitro and in vivo. | Synapse (New York, N.Y.) 20031215 |
Cortical alpha-adrenoceptor downregulation by tricyclic antidepressants in the rat brain. | Neurochemistry international 20031201 |
Effects of desipramine on regional serotonin synthesis in the rat brain: acute and chronic autoradiographic studies. | Neurochemistry international 20031201 |
Advances in the management of irritable bowel syndrome. | Current gastroenterology reports 20031201 |
Clinical and sociodemographic predictors of response to augmentation, or dose increase among depressed outpatients resistant to fluoxetine 20 mg/day. | Acta psychiatrica Scandinavica 20031201 |
Effect of the antidepressant desipramine on cytosolic Ca(2+) movement and proliferation in human osteosarcoma cells. | Pharmacology 20031201 |
In vivo monitoring of norepinephrine and its metabolites in skeletal muscle. | Neurochemistry international 20031101 |
Role of brain dopaminergic system in the adrenomedullin-induced diuresis and natriuresis. | Pharmacological research 20031101 |
Selectively bred Wistar-Kyoto rats: an animal model of depression and hyper-responsiveness to antidepressants. | Molecular psychiatry 20031101 |
Synthesis and pharmacological evaluation of (Z)-9-(heteroarylmethylene)-7-azatricyclo[4.3.1.0(3,7)]decanes: thiophene analogues as potent norepinephrine transporter inhibitors. | Bioorganic & medicinal chemistry letters 20031020 |
Effects of methylphenidate, desipramine, and L-dopa on attention and inhibition in children with Attention Deficit Hyperactivity Disorder. | Behavioural brain research 20031017 |
chi-Conopeptide MrIA partially overlaps desipramine and cocaine binding sites on the human norepinephrine transporter. | The Journal of biological chemistry 20031010 |
Antidepressant-induced increase in high-affinity rolipram binding sites in rat brain: dependence on noradrenergic and serotonergic function. | The Journal of pharmacology and experimental therapeutics 20031001 |
Functional reactivity of central cholinergic systems following desipramine treatments and sleep deprivation. | Naunyn-Schmiedeberg's archives of pharmacology 20031001 |
A new norepinephrine transporter imaging agent for cardiac sympathetic nervous function imaging: radioiodinated (R)-N-methyl-3-(2-iodophenoxy)-3-phenylpropanamine. | Nuclear medicine and biology 20031001 |
Pharmacological profile of the 5-HT-induced inhibition of cardioaccelerator sympathetic outflow in pithed rats: correlation with 5-HT1 and putative 5-ht5A/5B receptors. | British journal of pharmacology 20031001 |
Enhanced noradrenergic transmission in the spontaneously hypertensive rat anococcygeus muscle. | British journal of pharmacology 20031001 |
Effects of electroconvulsive seizures and antidepressant drugs on brain-derived neurotrophic factor protein in rat brain. | Biological psychiatry 20031001 |
Cytoprotective effect is one of common action pathways for antidepressants. | Acta pharmacologica Sinica 20031001 |
Mechanism-based inhibition of CYP activities in rat liver by fluoxetine and structurally similar alkylamines. | Xenobiotica; the fate of foreign compounds in biological systems 20031001 |
Phenylephrine induces endogenous noradrenaline release in the rat vas deferens through nitric oxide synthase pathway. | Pharmacology & toxicology 20031001 |
Effects of reboxetine on sympathetic neuroeffector transmission in rabbit carotid artery. | The Journal of pharmacology and experimental therapeutics 20030901 |
Duloxetine increases serotonin and norepinephrine availability in healthy subjects: a double-blind, controlled study. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030901 |
Validation of a simple, ethologically relevant paradigm for assessing anxiety in mice. | Biological psychiatry 20030901 |
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods. | Bioorganic & medicinal chemistry letters 20030818 |
Antidepressant-like effects in various mice strains in the tail suspension test. | Behavioural brain research 20030814 |
Intraaccumbens dopaminergic lesion suppresses desipramine effects in the forced swim test but not in the neuronal activity of lateral septal nucleus. | Progress in neuro-psychopharmacology & biological psychiatry 20030801 |
Comorbid major depressive disorder as a prognostic factor in cocaine-abusing buprenorphine-maintained patients treated with desipramine and contingency management. | The American journal of drug and alcohol abuse 20030801 |
Exaggerated effect of fluvoxamine in heterozygote serotonin transporter knockout mice. | Journal of neurochemistry 20030701 |
The effects of antidepressant treatment on serotonergic and dopaminergic systems in Fawn-Hooded rats: a quantitative autoradiography study. | Brain research 20030620 |
Regional brain metabolic correlates of alpha-methylparatyrosine-induced depressive symptoms: implications for the neural circuitry of depression. | JAMA 20030618 |
Inhibition of the norepinephrine transporter function in cultured bovine adrenal medullary cells by bisphenol A. | Biochemical pharmacology 20030615 |
Desipramine and contingency management for cocaine and opiate dependence in buprenorphine maintained patients. | Drug and alcohol dependence 20030605 |
Effects of 5-HT(6) receptor blockade on the neurochemical outcome of antidepressant treatment in the frontal cortex of the rat. | Journal of neural transmission (Vienna, Austria : 1996) 20030601 |
Tail-swing behavior: a novel animal model for anxiety. | Methods and findings in experimental and clinical pharmacology 20030601 |
Analysis of the effect of (-)-BPAP, a selective enhancer of the impulse propagation mediated release of catecholamines and serotonin in the brain. | Life sciences 20030509 |
Desipramine attenuates loss of cardiac sympathetic neurotransmitters produced by congestive heart failure and NE infusion. | American journal of physiology. Heart and circulatory physiology 20030501 |
Impact of maternal deprivation on brain corticotropin-releasing hormone circuits: prevention of CRH receptor-2 mRNA changes by desipramine treatment. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030501 |
Effects of reducing contingency management values on heroin and cocaine use for buprenorphine- and desipramine-treated patients. | Addiction (Abingdon, England) 20030501 |
Effects of selective serotonin reuptake inhibitors on immobility time in the tail suspension test in streptozotocin-induced diabetic mice. | Pharmacology, biochemistry, and behavior 20030501 |
Updates on attention deficit hyperactivity disorder, child abuse and neglect, and sudden infant death syndrome. | Current opinion in pediatrics 20030401 |
Uptake of 1-methyl-4-phenylpyridinium (MPP+) by the JAR human placental choriocarcinoma cell line: comparison with 5-hydroxytryptamine. | Placenta 20030401 |
1-Methyl-4-phenylpyridinium accumulates in cerebellar granule neurons via organic cation transporter 3. | Journal of neurochemistry 20030401 |
Sympathetic nerve destruction in spleen in murine AIDS. | Brain, behavior, and immunity 20030401 |
Regulation of GAP-43 expression by chronic desipramine treatment in rat cultured hippocampal cells. | Biological psychiatry 20030315 |
Binding and transport in norepinephrine transporters. Real-time, spatially resolved analysis in single cells using a fluorescent substrate. | The Journal of biological chemistry 20030314 |
Synthesis and characterization of iodine-123 labeled 2beta-carbomethoxy-3beta-(4'-((Z)-2-iodoethenyl)phenyl)nortropane. A ligand for in vivo imaging of serotonin transporters by single-photon-emission tomography. | Journal of medicinal chemistry 20030313 |
Age differences in the sensitivity to clomipramine in an animal model of obsessive-compulsive disorder. | Psychopharmacology 20030301 |
Duloxetine is both an inhibitor and a substrate of cytochrome P4502D6 in healthy volunteers. | Clinical pharmacology and therapeutics 20030301 |
Chronic inhibition of the norepinephrine transporter in the brain participates in seizure sensitization to cocaine and local anesthetics. | Brain research 20030221 |
Serotonin depletion in rat hippocampus attenuates L-NAME-induced spatial learning deficits. | Brain research 20030214 |
Affinity and specificity of N-methyl- D-aspartate channel blockers affect their ability to disrupt prepulse inhibition of acoustic startle in rats. | Psychopharmacology 20030201 |
Differential effects of K(ATP) channel blockers on [(3)H]-noradrenaline overflow after short- and long-term exposure to (+)-oxaprotiline or desipramine. | Naunyn-Schmiedeberg's archives of pharmacology 20030201 |
Antidepressant-induced switch of beta 1-adrenoceptor trafficking as a mechanism for drug action. | The Journal of biological chemistry 20030110 |
Inhibition of the oligosaccharides extracted from Morinda officinalis, a Chinese traditional herbal medicine, on the corticosterone induced apoptosis in PC12 cells. | Life sciences 20030110 |
Baseline prolactin and L-tryptophan availability predict response to antidepressant treatment in major depression. | Psychopharmacology 20030101 |
Comparison of desipramine or carbamazepine to placebo for crack cocaine-dependent patients. | The American journal on addictions 20030101 |
Prescribing cyclic antidepressants for vitiligo patients: which agents are superior, which are not? | Psychotherapy and psychosomatics 20030101 |
Antidepressant drug treatment induces Arc gene expression in the rat brain. | Neuroscience 20030101 |
[Attention deficit/hyperactivity disorder]. | Ryoikibetsu shokogun shirizu 20030101 |
Prediction of treatment outcome by baseline urine cocaine results and self-reported cocaine use for cocaine and opioid dependence. | The American journal of drug and alcohol abuse 20030101 |
Effects of combined treatment with imipramine and metyrapone in the forced swimming test in rats. Behavioral and pharmacokinetic studies. | Polish journal of pharmacology 20030101 |
Effects of classic and newer antidepressants on the oxidation pathways of caffeine in rat liver. In vitro study. | Polish journal of pharmacology 20030101 |
Treatment-related adverse events and outcome in a clinical trial of fluoxetine for major depressive disorder. | Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 20030101 |
Autonomic control after blockade of the norepinephrine transporter: a model of orthostatic intolerance. | Journal of applied physiology (Bethesda, Md. : 1985) 20021201 |
Alphaxalone, a neurosteroid anesthetic, inhibits norepinephrine transporter function in cultured bovine adrenal medullary cells. | Anesthesia and analgesia 20021201 |
The role of the conserved GXXXRXG motif in the expression and function of the human norepinephrine transporter. | Brain research. Molecular brain research 20021201 |
Comparison of the effects of antidepressants on norepinephrine and serotonin concentrations in the rat frontal cortex: an in-vivo microdialysis study. | Journal of psychopharmacology (Oxford, England) 20021201 |
Chronic antidepressant treatment increases the membrane expression of AMPA receptors in rat hippocampus. | Neuropharmacology 20021201 |
Acute treatment with the cyclic antidepressant desipramine, but not fluoxetine, increases membrane-associated G protein-coupled receptor kinases 2/3 in rat brain. | Neuropharmacology 20021201 |
Antidepressants reduce phosphoinositide-specific phospholipase C (PI-PLC) activity and the mRNA and protein expression of selective PLC beta 1 isozyme in rat brain. | Neuropharmacology 20021201 |
[Effect of local and systemic desipramine administration on extracellular noradrenaline in the myocardium of rats]. | Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20021201 |
In the rat forced swimming test, chronic but not subacute administration of dual 5-HT/NA antidepressant treatments may produce greater effects than selective drugs. | Behavioural brain research 20021115 |
Human variability in polymorphic CYP2D6 metabolism: is the kinetic default uncertainty factor adequate? | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20021101 |
Differential pre- and postsynaptic effects of desipramine on cardiac sympathetic nerve terminals in RHF. | American journal of physiology. Heart and circulatory physiology 20021101 |
Genotype- and experience-dependent susceptibility to depressive-like responses in the forced-swimming test. | Psychopharmacology 20021101 |
Effect of terbinafine on the pharmacokinetics and pharmacodynamics of desipramine in healthy volunteers identified as cytochrome P450 2D6 (CYP2D6) extensive metabolizers. | Journal of clinical pharmacology 20021101 |
Age-dependent changes of cardiac neuronal noradrenaline reuptake transporter (uptake1) in the human heart. | Journal of the American College of Cardiology 20021016 |
Relationship between alpha(1)-adrenergic receptor-induced contraction and extracellular signal-regulated kinase activation in the bovine inferior alveolar artery. | The Journal of pharmacology and experimental therapeutics 20021001 |
The effect of chronic oral desipramine on capsaicin-induced allodynia and hyperalgesia: a double-blinded, placebo-controlled, crossover study. | Anesthesia and analgesia 20021001 |
Allopregnanolone levels and symptom improvement in severe premenstrual syndrome. | Journal of clinical psychopharmacology 20021001 |
Inhibition of norepinephrine uptake in patients with major depression treated with paroxetine. | The American journal of psychiatry 20021001 |
The treatment of depression in patients maintained on dialysis. | Journal of psychosomatic research 20021001 |
Caspase 3 gene expression and [Ca2+]i homeostasis underlying desipramine-induced C6 glioma cell apoptosis. | Acta pharmacologica Sinica 20020901 |
Interaction of stress and noradrenergic drugs in the control of picrotoxin-induced seizures. | Epilepsy research 20020901 |
[Effects of antidepressants on the expression of rat brain dopamine receptors]. | [Hokkaido igaku zasshi] The Hokkaido journal of medical science 20020901 |
Enhanced antidepressant effect of sigma(1) (sigma(1)) receptor agonists in beta(25-35)-amyloid peptide-treated mice. | Behavioural brain research 20020821 |
Regulation of norepinephrine transporter abundance by catecholamines and desipramine in vivo. | Brain research 20020816 |
The SSRIs drug Fluoxetine, but not the noradrenergic tricyclic drug Desipramine, improves memory performance during acute major depression. | Brain research bulletin 20020815 |
Epinephrine in the heart: uptake and release, but no facilitation of norepinephrine release. | Circulation 20020813 |
Noradrenergic and serotonergic neuroendocrine responses in prepubertal, peripubertal, and postpubertal rats pretreated with desipramine and sertraline. | Journal of the American Academy of Child and Adolescent Psychiatry 20020801 |
Double-blind study of high-dose fluoxetine versus lithium or desipramine augmentation of fluoxetine in partial responders and nonresponders to fluoxetine. | Journal of clinical psychopharmacology 20020801 |
Tricyclic antidepressants and the Brugada syndrome: an example of Brugada waves appearing after the administration of desipramine. | Clinical cardiology 20020801 |
The antidepressant-like effect induced by the sigma(1) (sigma(1)) receptor agonist igmesine involves modulation of intracellular calcium mobilization. | Psychopharmacology 20020801 |
Gabapentin: new indication. In postherpetic neuralgia when amitriptyline fails. | Prescrire international 20020801 |
Inhibition of SK3 channels in the TE671 human medulloblastoma cell line by desipramine and imipramine. | European journal of pharmacology 20020719 |
Advanced glycation end-products induce apoptosis of bovine retinal pericytes in culture: involvement of diacylglycerol/ceramide production and oxidative stress induction. | Free radical biology & medicine 20020715 |
Effects of desipramine treatment on norepinephrine transporter gene expression in the cultured SK-N-BE(2)M17 cells and rat brain tissue. | Journal of neurochemistry 20020701 |
Sister chromatid exchanges produced by imipramine and desipramine in mouse bone marrow cells treated in vivo. | Toxicology letters 20020614 |
Antidepressant-like effects of cytidine in the forced swim test in rats. | Biological psychiatry 20020601 |
Inhibition of transport function and desipramine binding at the human noradrenaline transporter by N-ethylmaleimide and protection by substrate analogs. | Naunyn-Schmiedeberg's archives of pharmacology 20020601 |
Nicotinic acetylcholine receptor regulation of spinal norepinephrine release. | Anesthesiology 20020601 |
Reproductive hormonal treatments for mood disorders in women. | Dialogues in clinical neuroscience 20020601 |
Gonadal steroids, brain, and behavior: role of context. | Dialogues in clinical neuroscience 20020601 |
Modulatory effects of ketamine on catecholamine efflux from in vivo cardiac sympathetic nerve endings in cats. | Neuroscience letters 20020524 |
Effects of catecholamine uptake blockers in the caudate-putamen and subregions of the medial prefrontal cortex of the rat. | Brain research 20020517 |
Lack of cocaine effect on dopamine clearance in the core and shell of the nucleus accumbens of dopamine transporter knock-out mice. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20020515 |
Imipramine hydrochloride and desipramine hydrochloride as new reagents for detection of microamounts of blood in urine. | Journal of pharmaceutical and biomedical analysis 20020515 |
Characterization of nicotinic agonist-induced [(3)H]dopamine release from synaptosomes prepared from four mouse brain regions. | The Journal of pharmacology and experimental therapeutics 20020501 |
Orthostatic hypotension from sympathetic denervation in Parkinson's disease. | Neurology 20020423 |
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. | The Journal of biological chemistry 20020419 |
cAMP response element-binding protein is essential for the upregulation of brain-derived neurotrophic factor transcription, but not the behavioral or endocrine responses to antidepressant drugs. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20020415 |
Neuronal cell death induced by antidepressants: lack of correlation with Egr-1, NF-kappa B and extracellular signal-regulated protein kinase activation. | Biochemical pharmacology 20020415 |
Antidepressant reversal of interferon-alpha-induced anhedonia. | Physiology & behavior 20020415 |
Antidepressant activity of memory-enhancing drugs in the reduction of submissive behavior model. | European journal of pharmacology 20020405 |
Tramadol inhibits norepinephrine transporter function at desipramine-binding sites in cultured bovine adrenal medullary cells. | Anesthesia and analgesia 20020401 |
Desipramine antagonized corticosterone-induced apoptosis in cultured PC12 cells. | Acta pharmacologica Sinica 20020401 |
Sympathetic nervous system plays a major role in acute cold/restraint stress inhibition of host resistance to Listeria monocytogenes. | Journal of neuroimmunology 20020401 |
Functional significance of a highly conserved glutamate residue of the human noradrenaline transporter. | Journal of neurochemistry 20020401 |
Chronic behavioral disorders of human REM sleep: a new category of parasomnia. 1986 [classical article]. | Sleep 20020315 |
The effect of lofepramine and other related agents on the motility of Tetrahymena pyriformis. | Toxicology letters 20020310 |
Desipramine toxicity with terbinafine. | The American journal of psychiatry 20020301 |
Pharmacological properties of the naturally occurring Ala(457)Pro variant of the human norepinephrine transporter. | Pharmacogenetics 20020301 |
Leustroducsin B activates nuclear factor-kappaB via the acidic sphingomyelinase pathway in human bone marrow-derived stromal cell line KM-102. | Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20020301 |
Monoamine neurotoxins-induced apoptosis in lymphocytes by a common oxidative stress mechanism: involvement of hydrogen peroxide (H(2)O(2)), caspase-3, and nuclear factor kappa-B (NF-kappaB), p53, c-Jun transcription factors. | Biochemical pharmacology 20020215 |
Significant reduction of 125 I-meta-iodobenzylguanidine accumulation directly caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydroxypyridine, a toxic agent for inducing experimental Parkinson's disease. | Nuclear medicine communications 20020201 |
Brain 5-HT receptor system in the stressed infant rat: implications for vulnerability to substance abuse. | Psychoneuroendocrinology 20020101 |
Noradrenergic antidepressants: does chronic treatment increase or decrease nuclear CREB-P? | Journal of neural transmission (Vienna, Austria : 1996) 20020101 |
Falsely elevated imipramine levels in a patient taking quetiapine. | Journal of the American Academy of Child and Adolescent Psychiatry 20020101 |
Influence of ACTH on the effects of imipramine, desipramine and lithium on duration of immobility of rats in the forced swim test. | Pharmacology, biochemistry, and behavior 20020101 |
Norepinephrine metabolism in neuron: dissociation between 3,4-dihydroxyphenylglycol and 3,4-dihydroxymandelic acid pathways. | Acta pharmacologica Sinica 20020101 |
Seed finding in golden hamsters: a potential animal model for screening anxiolytic drugs. | Neuropsychobiology 20020101 |
Utility of crossover designs in clinical trials: efficacy of desipramine vs. placebo in opioid-dependent cocaine abusers. | The American journal on addictions 20020101 |
Treatment-resistant depression and Axis II comorbidity. | Psychotherapy and psychosomatics 20020101 |
Antidepressant-like effect of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist in the olfactory bulbectomized rats. | Amino acids 20020101 |
A 3D QSAR pharmacophore model and quantum chemical structure--activity analysis of chloroquine(CQ)-resistance reversal. | Journal of chemical information and computer sciences 20020101 |
Impact of criteria-based diagnosis of burning mouth syndrome on treatment outcome. | Journal of orofacial pain 20020101 |
Tyrosine residue 271 of the norepinephrine transporter is an important determinant of its pharmacology. | Brain research. Molecular brain research 20011216 |
Hyperactive phosphoinositide signaling pathway in platelets of depressed patients: effect of desipramine treatment. | Psychiatry research 20011215 |
Tricyclic antidepressants directly depress human myocardial mechanical function independent of effects on the conduction system. | Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20011201 |
Cerebral blood flow in obsessive-compulsive patients with major depression: effect of treatment with sertraline or desipramine on treatment responders and non-responders. | Psychiatry research 20011130 |
A new class of antiarrhythmic-defibrillatory agents. | Bioorganic & medicinal chemistry letters 20011119 |
Microheterogeneity of myocardial blood flow. | Basic research in cardiology 20011101 |
Increased neuronal activity in locus coeruleus from adult rats undernourished at perinatal age: its reversal by desipramine. | Life sciences 20011012 |
Concurrent use of oral contraceptives with antidepressants for premenstrual syndromes. | Journal of clinical psychopharmacology 20011001 |
Facilitation of Ca2+ store-dependent noradrenaline release after an N-methyl-D-aspartate receptor antagonist in the rat supraoptic nucleus. | Journal of neuroendocrinology 20011001 |
Sample preparation with fiber-in-tube solid-phase microextraction for capillary electrophoretic separation of tricyclic antidepressant drugs in human urine. | Electrophoresis 20011001 |
Lipopolysaccharide-mediated immobility in mice: reversal by cyclooxygenase enzyme inhibitors. | Methods and findings in experimental and clinical pharmacology 20011001 |
Differential time-course profiles of dopamine release and uptake changes induced by three dopamine uptake inhibitors. | Synapse (New York, N.Y.) 20010915 |
Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1. | American journal of physiology. Renal physiology 20010901 |
Antidepressant-like behavioral effects in 5-hydroxytryptamine(1A) and 5-hydroxytryptamine(1B) receptor mutant mice. | The Journal of pharmacology and experimental therapeutics 20010901 |
Noradrenergic modulation of serotonin release in rat dorsal and median raphé nuclei via alpha(1) and alpha(2A) adrenoceptors. | Neuropharmacology 20010901 |
Ischemic preconditioning attenuates cardiac sympathetic nerve injury via ATP-sensitive potassium channels during myocardial ischemia. | Circulation 20010828 |
Acute and chronic effects of desipramine and clorgyline on alpha(2)-adrenoceptors regulating noradrenergic transmission in the rat brain: a dual-probe microdialysis study. | British journal of pharmacology 20010801 |
Chronic desipramine treatment selectively potentiates somatostatin-induced dopamine release in the nucleus accumbens. | The European journal of neuroscience 20010801 |
A morpholinocatechol compound (UK42620) with clonidine- and tyramine-like actions. | Journal of autonomic pharmacology 20010801 |
A possible indirect sympathomimetic action of metformin in the arterial vessel wall of spontanously hypertensive rats. | Life sciences 20010720 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. | Journal of medicinal chemistry 20010719 |
Prejunctional actions of methylenedioxymethamphetamine in vas deferens from wild-type and alpha(2A/D)-adrenoceptor knockout mice. | European journal of pharmacology 20010706 |
Antidepressant-like actions of pregnancy, and progesterone in Wistar rats forced to swim. | Psychoneuroendocrinology 20010701 |
Cocaine or selective block of dopamine transporters influences multisecond oscillations in firing rate in the globus pallidus. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20010701 |
Involvement of GABAergic systems in manifestation of pharmacological activity of desipramine. | Japanese journal of pharmacology 20010701 |
Regional alterations of myocardial norepinephrine transporter density in streptozotocin-induced diabetic rats: implications for heterogeneous cardiac accumulation of MIBG in diabetes. | European journal of nuclear medicine 20010701 |
St. John's wort extract Ze 117 (Hypericum perforatum) inhibits norepinephrine and serotonin uptake into rat brain slices and reduces 3-adrenoceptor numbers on cultured rat brain cells. | Pharmacopsychiatry 20010701 |
Effects of Hypericum perforatum (St. John's wort) on passive avoidance in the rat: evaluation of potential neurochemical mechanisms underlying its antidepressant activity. | Pharmacopsychiatry 20010701 |
Effects of nociceptin on cardiac norepinephrine and acetylcholine release evoked by ouabain. | Brain research 20010615 |
Transcranial magnetic stimulation and antidepressive drugs share similar cellular effects in rat hippocampus. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20010601 |
Chronic treatment of C6 glioma cells with antidepressant drugs results in a redistribution of Gsalpha. | Molecular pharmacology 20010601 |
Relative bioavailability of imipramine (Tofranil) coated tablets in healthy volunteers. | International journal of clinical pharmacology and therapeutics 20010601 |
Association between depressive behavior and absence of serotonin-dopamine interaction in the nucleus accumbens. | Psychopharmacology 20010601 |
Uptake of the dopaminergic neurotoxin, norsalsolinol, into PC12 cells via dopamine transporter. | Archives of toxicology 20010601 |
Microdialysates of amines and metabolites from core nucleus accumbens of freely moving rats are altered by dizocilpine. | Brain research 20010525 |
Long-term impairment of anterograde axonal transport along fiber projections originating in the rostral raphe nuclei after treatment with fenfluramine or methylenedioxymethamphetamine. | Synapse (New York, N.Y.) 20010501 |
Antidepressant drug-induced alterations in neuron-localized tumor necrosis factor-alpha mRNA and alpha(2)-adrenergic receptor sensitivity. | The Journal of pharmacology and experimental therapeutics 20010501 |
Activity of phenothiazines against antibiotic-resistant Mycobacterium tuberculosis: a review supporting further studies that may elucidate the potential use of thioridazine as anti-tuberculosis therapy. | The Journal of antimicrobial chemotherapy 20010501 |
Dual phases of functional change in norepinephrine transporter in cultured bovine adrenal medullary cells by long-term treatment with clozapine. | Journal of neurochemistry 20010501 |
Sensitivity to the effects of pharmacologically selective antidepressants in different strains of mice. | Psychopharmacology 20010501 |
Lesion of the bulbospinal noradrenergic pathways blocks desipramine-induced inhibition of the C-fiber evoked nociceptive reflex in rats. | Neuroscience letters 20010413 |
Involvement of noradrenaline transporters in S-nitrosocysteine-stimulated noradrenaline release from rat brain slices: existence of functional Na(+)-independent transporter activity. | Neurochemistry international 20010401 |
Idazoxan and 8-OH-DPAT modify the behavioral effects induced by either NA, or 5-HT, or dual NA/5-HT reuptake inhibition in the rat forced swimming test. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20010401 |
Chip-based quantitative capillary electrophoresis/mass spectrometry determination of drugs in human plasma. | Analytical chemistry 20010401 |
Development of a depersonalization severity scale. | Journal of traumatic stress 20010401 |
Determination of residues in the norepinephrine transporter that are critical for tricyclic antidepressant affinity. | The Journal of biological chemistry 20010316 |
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes. | Journal of medicinal chemistry 20010315 |
Influence of chain length and N-alkylation on the selective serotonin receptor ligand 9-(aminomethyl)-9,10-dihydroanthracene. | Bioorganic & medicinal chemistry letters 20010312 |
Repeated electroconvulsive stimulation, but not antidepressant drugs, induces mossy fibre sprouting in the rat hippocampus. | Brain research 20010302 |
Low temperature prevents potentiation of norepinephrine release by phenylephrine. | Neurochemistry international 20010301 |
Dialysate dihydroxyphenylglycol as a window for in situ axoplasmic norepinephrine disposition. | Neurochemistry international 20010301 |
Determination of myocardial norepinephrine in freely moving rats using in vivo microdialysis sampling and liquid chromatography with dual-electrode amperometric detection. | Journal of pharmaceutical and biomedical analysis 20010301 |
Modulation of MK-801-induced behaviour by noradrenergic agents in mice. | Psychopharmacology 20010301 |
Comparison of noradrenergic and serotonergic antidepressants in reducing immobility time in the tail suspension test. | Japanese journal of pharmacology 20010301 |
Effect of hypothyroidism on pathways for iodothyronine and tryptophan uptake into rat adipocytes. | American journal of physiology. Endocrinology and metabolism 20010201 |
Release of amines from acidified stores following accumulation by Transport-P. | British journal of pharmacology 20010201 |
Norepinephrine reuptake is impaired in skeletal muscle of hypertensive rats in vivo. | Hypertension (Dallas, Tex. : 1979) 20010201 |
New reagents for detection of faecal occult blood. | Journal of pharmaceutical and biomedical analysis 20010201 |
Localization and characterization of a short isoform of the corticotropin-releasing factor receptor type 2alpha (CRF(2)alpha-tr) in the rat brain. | Biochemical and biophysical research communications 20010119 |
Antidepressants alter cell proliferation in the adult brain in vivo and in neural cultures in vitro. | European journal of pharmacology 20010105 |
Effects of chronic antidepressant treatments on 5-HT and NA transporters in rat brain: an autoradiographic study. | Neurochemistry international 20010101 |
Modifications in brain CaM kinase II after long-term treatment with desmethylimipramine. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20010101 |
Myocardial interstitial norepinephrine and dihydroxyphenylglycol levels during ischemia and reperfusion. | Cardiovascular research 20010101 |
Chronic treatment with desipramine facilitates its effect on extracellular noradrenaline in the rat hippocampus: studies on the role of presynaptic alpha2-adrenoceptors. | Naunyn-Schmiedeberg's archives of pharmacology 20010101 |
The effects of antidepressants on obstructed and unobstructed gait in healthy elderly people. | The journals of gerontology. Series A, Biological sciences and medical sciences 20010101 |
Vasopressin-dependent flank marking in golden hamsters is suppressed by drugs used in the treatment of obsessive-compulsive disorder. | BMC neuroscience 20010101 |
Antidepressants do not modulate estrogen receptor alpha-mediated gene expression. | Journal of neural transmission (Vienna, Austria : 1996) 20010101 |
National Patterns of Medication Treatment for Depression, 1987 to 2001. | Primary care companion to the Journal of clinical psychiatry 20010101 |
Clomipramine and related structures as inhibitors of the skeletal sarcoplasmic reticulum Ca2+ pump. | Journal of bioenergetics and biomembranes 20000401 |
Venlafaxine treatment of cocaine abusers with depressive disorders. | The American journal of drug and alcohol abuse 20000201 |
Antidepressant drugs appear to enhance cocaine-induced toxicity. | Experimental and clinical psychopharmacology 20000201 |
Effect of tolcapone on the haemodynamic effects and tolerability of desipramine. | European neurology 20000101 |
[Comparative study of hemodynamic effects of antidepressants (tetrindole and desipramine) during immobilization stress in hypertensive rats]. | Eksperimental'naia i klinicheskaia farmakologiia 20000101 |
Effects of chronic antidepressant treatments on serotonin transporter function, density, and mRNA level. | The Journal of neuroscience : the official journal of the Society for Neuroscience 19991201 |
Desipramine in opioid-dependent cocaine abusers maintained on buprenorphine vs methadone. | Archives of general psychiatry 19990901 |
The toxicity of 6-hydroxydopamine on PC12 and P19 cells. | Brain research. Molecular brain research 19990521 |
Functional characterization of an organic cation transporter (hOCT1) in a transiently transfected human cell line (HeLa). | The Journal of pharmacology and experimental therapeutics 19980701 |
The effect of antidepressants on rat aggressive behavior in the electric footshock and apomorphine-induced aggressiveness paradigms. | Methods and findings in experimental and clinical pharmacology 19980501 |
Apomorphine-induced aggressiveness and [3H]citalopram binding after antidepressant treatment in rats. | Pharmacology, biochemistry, and behavior 19980301 |
Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. | The Journal of pharmacology and experimental therapeutics 19971201 |
Haloperidol-induced catalepsy: a model for screening antidepressants effective in treatment of depression with Parkinson's disease. | Indian journal of experimental biology 19971201 |
Neuropathy associated with tricyclic antidepressants. | International journal of geriatric psychiatry 19970801 |
Cloning and characterization of two human polyspecific organic cation transporters. | DNA and cell biology 19970701 |
Withdrawal hypomania associated with paroxetine. | Journal of clinical psychopharmacology 19970201 |
Probable nefazodone-induced mania in a patient with unreported bipolar disorder. | Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 19961201 |
Reduction of substance P after chronic antidepressants treatment in the striatum, substantia nigra and amygdala of the rat. | Brain research 19961111 |
Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus. | The Journal of neuroscience : the official journal of the Society for Neuroscience 19960401 |
Nitric oxide contributes to desipramine-induced hypotension in rats. | Human & experimental toxicology 19960401 |
Effect of calcium chloride and 4-aminopyridine therapy on desipramine toxicity in rats. | Journal of toxicology. Clinical toxicology 19960101 |
Reduction of desipramine cardiotoxicity and prolongation of survival in rats with the use of polyclonal drug-specific antibody Fab fragments. | Annals of emergency medicine 19950901 |
Inhibition by antidepressant drugs of cyclic AMP response element-binding protein/cyclic AMP response element-directed gene transcription. | Molecular pharmacology 19950601 |
A new cytochrome P450 form belonging to the CYP2D in dog liver microsomes: purification, cDNA cloning, and enzyme characterization. | Archives of biochemistry and biophysics 19950601 |
Chronic antidepressant treatment down-regulates the induction of c-fos mRNA in response to acute stress in rat frontal cortex. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 19950501 |
Blood dyscrasias with carbamazepine and valproate: a pharmacoepidemiological study of 2,228 patients at risk. | The American journal of psychiatry 19950301 |
Beneficial effects of co-administration of catechol-O-methyltransferase inhibitors and L-dihydroxyphenylalanine in rat models of depression. | European journal of pharmacology 19950214 |
Mixed mania: apparent induction by a tricyclic antidepressant in five consecutively treated patients with bipolar depression. | Biological psychiatry 19950101 |
A double-blind trial of bupropion versus desipramine for bipolar depression. | The Journal of clinical psychiatry 19940901 |
Severe imipramine-induced myoclonus in a patient with psychotic bipolar depression, catatonia, and schizencephaly. | Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 19940301 |
Characteristics of desipramine-refractory depression. | The Journal of clinical psychiatry 19940101 |
The role of receptor binding in drug discovery. | Journal of natural products 19930401 |
Amphetamine and antidepressant drug effects on GABA- and NMDA-related seizures. | Brain research bulletin 19930101 |
Genetically determined drug-metabolizing activity and desipramine-associated cardiotoxicity: a case report. | Clinical pharmacology and therapeutics 19930101 |
Potential mechanism of desipramine-related sudden death in children. | Psychosomatics 19930101 |
Desipramine-induced oral-pharyngeal disturbances: stuttering and jaw myoclonus. | Journal of clinical psychopharmacology 19921201 |
Bupropion-induced carbohydrate craving and weight gain. | The American journal of psychiatry 19921001 |
Sudden self-harm while taking fluoxetine. | The American journal of psychiatry 19920801 |
Increased pulse and blood pressure associated with desipramine treatment of bulimia nervosa. | Journal of clinical psychopharmacology 19920601 |
Trazodone induction of migraine headache through mCPP. | The American journal of psychiatry 19920501 |
Effect of IAP and chronic antidepressant administration on the 5HT1A receptor in rat cortical membranes. | Progress in neuro-psychopharmacology & biological psychiatry 19920501 |
Oral contraceptives and panic disorder. | The Journal of clinical psychiatry 19920501 |
Reversal of desipramine toxicity in rats using drug-specific antibody Fab' fragment: effects on hypotension and interaction with sodium bicarbonate. | The Journal of pharmacology and experimental therapeutics 19920301 |
Control of depression with fluoxetine and antiseizure medication in a brain-injured patient. | The American journal of psychiatry 19920201 |
Low dose desipramine treatment of cocaine-related panic attacks. | The Journal of nervous and mental disease 19911201 |
Regulation of serotonin type 2 (5-HT2) and beta-adrenergic receptors in rat cerebral cortex following novel and classical antidepressant treatment. | Journal of psychiatry & neuroscience : JPN 19911101 |
Repeated administration of desmethylimipramine blocks the reserpine-induced increase in tyrosine hydroxylase mRNA in locus coeruleus neurons of the rat. | Brain research. Molecular brain research 19910701 |
Changes in convulsion susceptibility of lidocaine by alteration of brain catecholaminergic functions. | Japanese journal of pharmacology 19910501 |
2-Hydroxydesipramine and desipramine plasma levels and electrocardiographic effects in depressed younger adults. | Journal of clinical psychopharmacology 19910401 |
Symptoms of major depression: acute effect of withdrawing antidepressants. | Acta psychiatrica Scandinavica 19910301 |
Low dose tricyclic tachycardia. | Journal of the American Academy of Child and Adolescent Psychiatry 19910101 |
Pediatric cardiovascular effects of imipramine and desipramine. | Journal of the American Academy of Child and Adolescent Psychiatry 19910101 |
Sudden death in children receiving Norpramin: a review of three reported cases and commentary. | Journal of the American Academy of Child and Adolescent Psychiatry 19910101 |
Hyperprolactinemia and risk for relapse of cocaine abuse. | Biological psychiatry 19901101 |
The selective serotonin reuptake inhibitor paroxetine is effective in the treatment of diabetic neuropathy symptoms. | Pain 19900801 |
Serious adverse effects of combining fluoxetine and tricyclic antidepressants. | The American journal of psychiatry 19900401 |
Desipramine relieves postherpetic neuralgia. | Clinical pharmacology and therapeutics 19900301 |
Noradrenergic mechanisms appear not to be involved in cocaine-induced seizures and lethality. | Life sciences 19900101 |
Protracted ventricular arrhythmias occurring after abrupt tricyclic antidepressant withdrawal. | Psychosomatics 19900101 |
Ventricular tachycardia associated with desipramine and thioridazine. | Psychosomatics 19900101 |
A double-blind placebo controlled study of desipramine in the treatment ADD: II. Serum drug levels and cardiovascular findings. | Journal of the American Academy of Child and Adolescent Psychiatry 19891101 |
Hypersensitivity myocarditis and hepatitis associated with imipramine and its metabolite, desipramine. | Journal of forensic sciences 19890701 |
Effects of chronic antidepressant and benzodiazepine treatment on corticotropin-releasing-factor receptors in rat brain and pituitary. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 19890301 |
Use of yohimbine to counteract nortriptyline-induced orthostatic hypotension. | Journal of clinical psychopharmacology 19890201 |
Corticotropin-releasing factor: putative neurotransmitter in the noradrenergic nucleus locus ceruleus. | Psychopharmacology bulletin 19890101 |
Treatment-emergent depression with antidepressants in panic disorder. | Comprehensive psychiatry 19890101 |
Fluoxetine induces elevation of desipramine level and exacerbation of geriatric nonpsychotic depression. | Journal of clinical psychopharmacology 19881201 |
Relapse to cocaine abuse after initiating desipramine treatment. | JAMA 19881104 |
Episodic barrel rotations induced by intrastriatal injection of quinolinic acid in rats. Inhibition by anticonvulsants. | Pharmacology, biochemistry, and behavior 19880901 |
Desipramine-induced conduction disorder. | Postgraduate medicine 19880701 |
The jitteriness syndrome in panic disorder patients treated with antidepressants. | The Journal of clinical psychiatry 19880301 |
Anorgasmia associated with desipramine. | Canadian journal of psychiatry. Revue canadienne de psychiatrie 19880201 |
The effects of chronic antidepressant treatment in an animal model of anxiety. | Psychopharmacology 19880101 |
Desipramine and testicular swelling in two patients. | The Journal of clinical psychiatry 19880101 |
Transient mood elevation associated with antidepressant drug decrease. | Canadian journal of psychiatry. Revue canadienne de psychiatrie 19871201 |
Increased adult behavioral 'despair' in rats neonatally exposed to desipramine or zimeldine: an animal model of depression? | Pharmacology, biochemistry, and behavior 19871101 |
Response of tardive and L-dopa-induced dyskinesias to antidepressants. | The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 19871101 |
Possible toxic interaction between cyproheptadine and phenelzine. | The American journal of psychiatry 19870901 |
A grand mal seizure associated with desipramine and haloperidol. | Canadian journal of psychiatry. Revue canadienne de psychiatrie 19870801 |
Hypersensitivity reaction to desipramine. | The Journal of allergy and clinical immunology 19870701 |
Testicular swelling associated with desipramine. | The Journal of clinical psychiatry 19870601 |
Cardiac myonecrosis in hypertensive crisis associated with monoamine oxidase inhibitor therapy. | The American journal of medicine 19870501 |
Imipramine and tinnitus. | The Journal of clinical psychiatry 19870301 |
Occurrence of myoclonus in patients treated with cyclic antidepressants. | Archives of general psychiatry 19870301 |
Effects of antihypertensive drugs on sympathetic vascular control in relation to neuropeptide Y. | Journal of cardiovascular pharmacology 19870101 |
Noradrenergic involvement in catalepsy induced by delta 9-tetrahydrocannabinol. | Neuropharmacology 19870101 |
[Torsade de pointes caused by tricyclic antidepressive agents. Description of a clinical case]. | Giornale italiano di cardiologia 19861201 |
Nocturnal cataclysms with myoclonus: a new side effect of clomipramine. | The American journal of psychiatry 19861101 |
Profound behavioral toxicity due to tricyclic antidepressants. | The Journal of nervous and mental disease 19861001 |
Transient contralateral rotation following unilateral substantia nigra lesion reflects susceptibility of the nigrostriatal system to exhaustion by amphetamine. | Life sciences 19860707 |
Painful postcoital testicular retraction linked with desipramine. | The American journal of psychiatry 19860501 |
Speech blockage induced by maprotiline. | The American journal of psychiatry 19860301 |
Mechanism of the tachycardia following systemic alpha-methyldopa administration in conscious rats. | Journal of cardiovascular pharmacology 19860101 |
Central noradrenaline depletion antagonizes aspects of d-amphetamine-induced hyperactivity in the rat. | Psychopharmacology 19860101 |
Behavioral depression following clonidine withdrawal: a new animal model of long-lasting depression? | Psychopharmacology bulletin 19860101 |
Two cases of hypomania following the addition of L-tryptophan to a monoamine oxidase inhibitor. | The American journal of psychiatry 19851201 |
Chronic but not acute treatment with antidepressants enhances the electroconvulsive seizure response in rats. | Neuropharmacology 19851001 |
Desipramine-induced delirium at 'subtherapeutic' concentrations: a case report. | Canadian journal of psychiatry. Revue canadienne de psychiatrie 19850801 |
Trazodone-induced mania following desipramine-induced mania in major depressive disorders. | The American journal of psychiatry 19850301 |
Manic symptoms following addition of lithium to antidepressant treatment. | Journal of clinical psychopharmacology 19841201 |
Identifying depression secondary to lithium-induced hypothyroidism. | Psychosomatics 19841101 |
Use of desipramine in depressed inpatients. | The Journal of clinical psychiatry 19841001 |
Treatment of outpatients with desipramine. | The Journal of clinical psychiatry 19841001 |
Use of desipramine in the medically ill. | The Journal of clinical psychiatry 19841001 |
Carbamazepine-induced tics. | Developmental medicine and child neurology 19840801 |
Desipramine in the treatment of adolescents with attention deficit disorder. | The American journal of psychiatry 19840701 |
Changes in amphetamine-induced anorexia and stereotypy during chronic treatment with antidepressant drugs. | European journal of pharmacology 19840302 |
Antidepressant versus neuroleptic activities of sulpiride isomers on four animal models of depression. | Psychopharmacology 19840101 |
Comparison of the (pro)convulsive properties of fluvoxamine and clovoxamine with eight other antidepressants in an animal model. | Neuropsychobiology 19840101 |
Subjective complaints during desipramine treatment. Relative importance of plasma drug concentrations and the severity of depression. | Archives of general psychiatry 19840101 |
Evidence for a selective brain noradrenergic involvement in the locomotor stimulant effects of amphetamine in the rat. | Neuroscience letters 19831230 |
Desipramine in the treatment of hypersomnolence following abrupt cessation of cocaine use. | The American journal of psychiatry 19831101 |
Anorgasmia associated with imipramine but not desipramine: case report. | The Journal of clinical psychiatry 19830901 |
Desipramine-associated hepatitis. | Journal of clinical psychopharmacology 19830801 |
Hypomania after desipramine withdrawal. | The American journal of psychiatry 19830501 |
Desipramine-associated SIADH in an elderly woman: case report. | The Journal of clinical psychiatry 19830401 |
Q-T prolongation and torsades de pointes ventricular tachycardia produced by the tetracyclic antidepressant agent maprotiline. | The American journal of cardiology 19830301 |
Somatic symptoms in depression and antidepressants. | The Journal of clinical psychiatry 19830101 |
Major adverse reactions during desipramine treatment: relationship to plasma drug concentrations, concomitant antipsychotic treatment, and patient characteristics. | Archives of general psychiatry 19820901 |
Possible involvement of serotonergic neurons in the reduction of locomotor hyperactivity caused by amphetamine in neonatal rats depleted of brain dopamine. | Brain research 19820722 |
(+/-)-4-Aryl-4,5-dihydro-3H-1,3-benzodiazepines. 1. Synthesis and evaluation of (+/-)-4,5-dihydro-2,3-dimethyl-4-phenyl-3H-1,3-benzodiazepine and analogues as potential antidepressant agents. | Journal of medicinal chemistry 19820401 |
Sexual dysfunction and clomipramine. | Canadian journal of psychiatry. Revue canadienne de psychiatrie 19820401 |
Pupil studies in depressed patients: an investigation of the mechanism of action of desipramine. | The British journal of psychiatry : the journal of mental science 19820201 |
Variant ventricular tachycardia in desipramine toxicity. | Southern medical journal 19811001 |
Inappropriate ADH secretion: the role of drug re-challenge. | Psychosomatics 19800901 |
Hoarseness and tricyclic antidepressants. | The American journal of psychiatry 19800501 |
Effect of acute and chronic treatment of tandamine, a new heterocyclic antidepressant, on biogenic amine metabolism and related activities. | Naunyn-Schmiedeberg's archives of pharmacology 19790901 |
Chronic treatment with antidepressant drugs: potentiation of apomorphine-induced aggressive behaviour in rats. | Neuroscience letters 19790801 |
Rapid cycling in manic-depressives induced by tricyclic antidepressants. | Archives of general psychiatry 19790501 |
High dose desipramine, plasma drug levels and clinical response. | The Journal of clinical psychiatry 19790301 |
Inappropriate antidiuresis during desipramine therapy. | Archives of internal medicine 19781101 |
Cardiovascular responses to mianserin hydrochloride: a comparison with tricyclic antidepressant drugs. | British journal of clinical pharmacology 19780101 |
Clinical pharmacological studies of tandamine, a potential antidepressive drug. | Psychopharmacology 19770323 |
Effects of viloxazine, an antidepressant agent, on biogenic amine uptake mechanisms and related activities. | Canadian journal of physiology and pharmacology 19760801 |
On the anticataleptic action of cyproheptadine. | Pharmacology, biochemistry, and behavior 19760801 |
Peripherally and centrally mediated bradycardiac effects of clonidine in anesthetized or spinal rats. | The Tohoku journal of experimental medicine 19760701 |
Centrally mediated cardiovascular effects of intracisternal application of carbachol in anesthetized rats. | Japanese journal of pharmacology 19760601 |
Ascending catecholamine pathways and amphetamine-induced locomotor activity: importance of dopamine and apparent non-involvement of norepinephrine. | Brain research 19750815 |
Interaction between digoxin and tricyclic antidepressants in the rat. | European journal of pharmacology 19720801 |
Inhibition of extrapyramidal side effects of haloperidol through the joint use of imipramine-type drugs. | Psychosomatics 19720101 |
Tricyclic antidepressants and monoamine oxidase inhibitors. | Archives of general psychiatry 19710601 |
Haloperidol-desipramine interaction in mice, rats and man. | Chemico-biological interactions 19700801 |
[Mechanism of inversion by demethylimipramine of motor depression induced by tetrabenazine]. | Farmakologiia i toksikologiia 19690101 |