5-HYDROXY-2'-DEOXYCYTIDINE
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In vivo treatment with aflatoxin B1 increases DNA oxidation, base excision repair activity and 8-oxoguanine DNA glycosylase 1 levels in mouse lung. | Toxicology 20140703 |
Mutagen-mediated enhancement of HIV-1 replication in persistently infected cells. | Virology 20120315 |
Thermodynamic signature of DNA damage: characterization of DNA with a 5-hydroxy-2'-deoxycytidine·2'-deoxyguanosine base pair. | Biochemistry 20120306 |
Mutation of HIV-1 genomes in a clinical population treated with the mutagenic nucleoside KP1461. | PloS one 20110101 |
Defective repair of 5-hydroxy-2'-deoxycytidine in Cockayne syndrome cells and its complementation by Escherichia coli formamidopyrimidine DNA glycosylase and endonuclease III. | Free radical biology & medicine 20100301 |
Antimicrobial strategies: inhibition of viral polymerases by 3'-hydroxyl nucleosides. | Drugs 20090101 |
Reaction of 2'-deoxycytidine with peroxynitrite in the presence of ammonium bromide. | Bioorganic & medicinal chemistry 20080501 |
Major oxidative products of cytosine are substrates for the nucleotide incision repair pathway. | DNA repair 20070104 |
Synthesis and antiviral activity of 5-substituted cytidine analogues: identification of a potent inhibitor of viral RNA-dependent RNA polymerases. | Journal of medicinal chemistry 20061019 |
Ascorbate and H2O2 induced oxidative DNA damage in Jurkat cells. | Free radical biology & medicine 20060615 |
Oxidation of 5-hydroxypyrimidine nucleosides to 5-hydroxyhydantoin and its alpha-hydroxy-ketone isomer. | Chemical research in toxicology 20050801 |
Combination of a mutagenic agent with a reverse transcriptase inhibitor results in systematic inhibition of HIV-1 infection. | Virology 20050720 |
Effect of chemical modifications of cytosine and guanine in a CpG-motif of oligonucleotides: structure-immunostimulatory activity relationships. | Bioorganic & medicinal chemistry 20010301 |
The role of duck hepatitis B virus and aflatoxin B1 in the induction of oxidative stress in the liver. | Cancer detection and prevention 20010101 |
Lethal mutagenesis of HIV with mutagenic nucleoside analogs. | Proceedings of the National Academy of Sciences of the United States of America 19990216 |
New substrates for old enzymes. 5-Hydroxy-2'-deoxycytidine and 5-hydroxy-2'-deoxyuridine are substrates for Escherichia coli endonuclease III and formamidopyrimidine DNA N-glycosylase, while 5-hydroxy-2'-deoxyuridine is a substrate for uracil DNA N-glycosylase. | The Journal of biological chemistry 19940722 |