BERBAMINE
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In vitro and in vivo metabolic activation of berbamine to quinone methide intermediate. | Journal of biochemical and molecular toxicology 20170401 |
Novel synthetic derivatives of the natural product berbamine inhibit Jak2/Stat3 signaling and induce apoptosis of human melanoma cells. | Molecular oncology 20121001 |
Emerging role of berbamine as an anti-cancer agent in systemic malignancies besides chronic myeloid leukemia. | Journal of Zhejiang University. Science. B 20120901 |
Synthesis of berbamine acetyl glycosides and evaluation of antitumor activity. | European journal of medicinal chemistry 20120801 |
Cancer stem cells and the impact of Chinese herbs, isolates and other complementary medical botanicals: a review. | Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20120501 |
Berbamine protects the heart from ischemia/reperfusion injury by maintaining cytosolic Ca(2+) homeostasis and preventing calpain activation. | Circulation journal : official journal of the Japanese Circulation Society 20120101 |
The interaction of telomere DNA G-quadruplex with three bis-benzyltetrahydroisoquinoline alkaloids. | Nucleic acid therapeutics 20111201 |
[Inhibitory effect of 4-chlorobenzoyl berbamine on imatinib-resistant K562 cells in vitro and in vivo]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20111201 |
Berbamine overcomes imatinib-induced neutropenia and permits cytogenetic responses in Chinese patients with chronic-phase chronic myeloid leukemia. | International journal of hematology 20110801 |
Berbamine inhibits proliferation and induces apoptosis of KU812 cells by increasing Smad3 activity. | Journal of Zhejiang University. Science. B 20110701 |
Berbamine increases myocardial contractility via a Ca2+-independent mechanism. | Journal of cardiovascular pharmacology 20110701 |
Systematic review of herbals as potential anti-inflammatory agents: Recent advances, current clinical status and future perspectives. | Pharmacognosy reviews 20110101 |
Chronic inflammation in cancer development. | Frontiers in immunology 20110101 |
Suppression of human lung cancer cell growth and migration by berbamine. | Cytotechnology 20100801 |
A novel calmodulin antagonist O-(4-ethoxyl-butyl)-berbamine overcomes multidrug resistance in drug-resistant MCF-7/ADR breast carcinoma cells. | Journal of pharmaceutical sciences 20100701 |
4-Chlorobenzoyl berbamine induces apoptosis and G2/M cell cycle arrest through the PI3K/Akt and NF-kappaB signal pathway in lymphoma cells. | Oncology reports 20100301 |
Degradation of HER2/neu by ANT2 shRNA suppresses migration and invasiveness of breast cancer cells. | BMC cancer 20100101 |
Circumvention of multi-drug resistance of cancer cells by Chinese herbal medicines. | Chinese medicine 20100101 |
Tissue culture and generation of autotetraploid plants of Sophora flavescens Aiton. | Pharmacognosy magazine 20100101 |
Traditional herbal medicine in far-west Nepal: a pharmacological appraisal. | Journal of ethnobiology and ethnomedicine 20100101 |
Berbamine, a novel nuclear factor kappaB inhibitor, inhibits growth and induces apoptosis in human myeloma cells. | Acta pharmacologica Sinica 20091201 |
[Berbamine induces apoptosis of multiple myeloma RPMI 8226 cells by activating GADD45/JNK pathway]. | Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20090901 |
Berbamine derivatives: a novel class of compounds for anti-leukemia activity. | European journal of medicinal chemistry 20090801 |
The antiproliferation effect of berbamine on k562 resistant cells by inhibiting NF-kappaB pathway. | Anatomical record (Hoboken, N.J. : 2007) 20090701 |
[Mechanism related to inhibition of leukemia K562 cells by berbamine]. | Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20090701 |
Probing the binding sites and the effect of berbamine on the structure of bovine serum albumin. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20090601 |
Antihyperglycemic and antioxidant effect of Berberis aristata root extract and its role in regulating carbohydrate metabolism in diabetic rats. | Journal of ethnopharmacology 20090504 |
Berbamine exhibits potent antitumor effects on imatinib-resistant CML cells in vitro and in vivo. | Acta pharmacologica Sinica 20090401 |
Effects of theanine on growth of human lung cancer and leukemia cells as well as migration and invasion of human lung cancer cells. | Cytotechnology 20090401 |
A new dawn for the use of traditional Chinese medicine in cancer therapy. | Molecular cancer 20090101 |
Berbamine induces Fas-mediated apoptosis in human hepatocellular carcinoma HepG2 cells and inhibits its tumor growth in nude mice. | Journal of Asian natural products research 20090101 |
Suppression of growth, migration and invasion of highly-metastatic human breast cancer cells by berbamine and its molecular mechanisms of action. | Molecular cancer 20090101 |
Harnessing gene expression to identify the genetic basis of drug resistance. | Molecular systems biology 20090101 |
Pharmacological and therapeutic effects of Berberis vulgaris and its active constituent, berberine. | Phytotherapy research : PTR 20080801 |
Novel immunomodulatory properties of berbamine through selective down-regulation of STAT4 and action of IFN-gamma in experimental autoimmune encephalomyelitis. | Journal of immunology (Baltimore, Md. : 1950) 20080715 |
Studies on alkaloids binding to GC-rich human survivin promoter DNA using positive and negative ion electrospray ionization mass spectrometry. | Journal of mass spectrometry : JMS 20080301 |
Berbamine selectively induces apoptosis of human acute promyelocytic leukemia cells via survivin-mediated pathway. | Chinese medical journal 20070505 |
Berbamine induces apoptosis in human hepatoma cell line SMMC7721 by loss in mitochondrial transmembrane potential and caspase activation. | Journal of Zhejiang University. Science. B 20070401 |
Free radical scavenging activity and lipoxygenase inhibition of Mahonia aquifolium extract and isoquinoline alkaloids. | Journal of inflammation (London, England) 20070101 |
Regulatory T cells, a potent immunoregulatory target for CAM researchers: modulating tumor immunity, autoimmunity and alloreactive immunity (III). | Evidence-based complementary and alternative medicine : eCAM 20060901 |
[The mechanism of apoptosis of chronic myeloid leukemia cells induced by the novel p210 bcr/abl inhibitor berbamine]. | Zhonghua yi xue za zhi 20060829 |
[Effects of berbamine on growth of leukemia cell line NB4 and its mechanism]. | Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20060301 |
Berbamine: a novel inhibitor of bcr/abl fusion gene with potent anti-leukemia activity. | Leukemia research 20060101 |
[Progress of cardiovascular pharmacologic study on berbamine]. | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20050801 |
[Effects of berbamine on K562 cells and its mechanisms in vitro and in vivo]. | Zhongguo shi yan xue ye xue za zhi 20050601 |
[Study on effect of berbamine on multidrug resistance leukemia K562/Adr cells]. | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20040901 |
[Comparison of the anti-arrhythmic effects of matrine and berbamine with amiodarone and RP58866]. | Yao xue xue bao = Acta pharmaceutica Sinica 20040901 |
[Distribution of four alkaloids in plants of Berberis]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20040201 |
[Reversal effect of berbamine on multidrug resistance of K562/A02 cells and its mechanism]. | Zhongguo shi yan xue ye xue za zhi 20031201 |
[Determination of four alkaloids in Berberis plants by HPLC]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20031201 |
Effect of E6, a novel calmodulin inhibitor, on activity of P-glycoprotein in purified primary cultured rat brain microvessel endothelial cells. | Acta pharmacologica Sinica 20031101 |
Inhibition of Na(+),K(+)-ATPase by the extract of Stephania cephararantha HAYATA and bisbenzylisoquinoline alkaloid cycleanine, a major constituent. | Biochemical pharmacology 20030801 |
[Detection of P-170 and treatment with berbamine in primary acute leukemia]. | Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20030201 |
Integrity of actin-network is involved in uridine 5'-triphosphate evoked store-operated Ca2+ entry in bovine adrenocortical fasciculata cells. | Journal of pharmacological sciences 20030101 |
A comparative study on the anti-inflammatory, antinociceptive and antipyretic effects of isoquinoline alkaloids from the roots of Turkish Berberis species. | Life sciences 20021227 |
Effects of various principles from Chinese herbal medicine on rhodamine123 accumulation in brain capillary endothelial cells. | Acta pharmacologica Sinica 20020701 |
Inhibition of telomerase activity and bcl-2 expression in berbamine-induced apoptosis in HL-60 cells. | Planta medica 20020701 |
Interaction of multidrug resistance reversal agents with P-glycoprotein ATPase activity on blood-brain barrier. | Acta pharmacologica Sinica 20020501 |
The effect of calmodulin antagonist berbaminederivative-EBB on hepatoma in vitro and in vivo. | Chinese medical journal 20020501 |
Effect of Mahonia aquifolium active compounds on interleukin-8 production in the human monocytic cell line THP-1. | Planta medica 20020301 |
Potential antimutagenic activity of berberine, a constituent of Mahonia aquifolium. | BMC complementary and alternative medicine 20020101 |
Analytical approaches for traditional chinese medicines exhibiting antineoplastic activity. | Journal of chromatography. B, Biomedical sciences and applications 20011125 |
Protection of T cells from radiation-induced apoptosis by Cepharanthin. | International immunopharmacology 20011101 |
In vitro effect of alkaloids on bloodstream forms of Trypanosoma brucei and T. congolense. | Planta medica 20011001 |