Home Aminos N,N'-bis(salicylideneamino)ethane-manganese(II)

N,N'-bis(salicylideneamino)ethane-manganese(II)

CAS No.:
53177-12-1
Catalog Number:
AG00DBVU
Molecular Formula:
C16H14ClMnN2O2
Molecular Weight:
356.6856
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Product Description
Catalog Number:
AG00DBVU
Chemical Name:
N,N'-bis(salicylideneamino)ethane-manganese(II)
CAS Number:
53177-12-1
Molecular Formula:
C16H14ClMnN2O2
Molecular Weight:
356.6856
MDL Number:
MFCD00933789
IUPAC Name:
manganese(3+);2-[2-[(2-oxidophenyl)methylideneamino]ethyliminomethyl]phenolate;chloride
InChI:
InChI=1S/C16H16N2O2.ClH.Mn/c19-15-7-3-1-5-13(15)11-17-9-10-18-12-14-6-2-4-8-16(14)20;;/h1-8,11-12,19-20H,9-10H2;1H;/q;;+3/p-3
InChI Key:
HBQGFROGWOHBAG-UHFFFAOYSA-K
SMILES:
[O-]c1ccccc1/C=[N-]/CC/[N-]=C\c1ccccc1[O-].[Cl-].[Mn+5]
Properties
Complexity:
298  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
3  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
356.012g/mol
Formal Charge:
0
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
356.688g/mol
Monoisotopic Mass:
356.012g/mol
Rotatable Bond Count:
5  
Topological Polar Surface Area:
70.8A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
Inhibition of human islet amyloid polypeptide or amylin aggregation by two manganese-salen derivatives. European journal of pharmacology 20130505
Biomimetic in vitro oxidation of lapachol: a model to predict and analyse the in vivo phase I metabolism of bioactive compounds. European journal of medicinal chemistry 20120801
Amelioration of diet-induced nonalcoholic steatohepatitis in rats by Mn-salen complexes via reduction of oxidative stress. Journal of biomedical science 20120101
Antioxidant therapy attenuates myocardial telomerase activity reduction in superoxide dismutase-deficient mice. Journal of molecular and cellular cardiology 20110401
Apoptosis-inducing factor regulates skeletal muscle progenitor cell number and muscle phenotype. PloS one 20110101
Salen-manganese complexes: sophisticated tools for the analysis of intercellular ROS signaling pathways. Anticancer research 20101001
Restraint stress up-regulates lectin-like oxidized low-density lipoprotein receptor-1 in aorta of apolipoprotein E-deficient mice. Stress (Amsterdam, Netherlands) 20100901
Asymmetric epoxidation of unfunctionalized alkenes catalyzed by sugar moiety-modified chiral salen-Mn(III) complexes. Carbohydrate research 20090105
Fluorimetric study of the pro-oxidant activity of EUK8 in the presence of hydrogen peroxide. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20080801
Role of superoxide dismutase enzymes and ascorbate in protection of nitrergic relaxation against superoxide anions in mouse duodenum. Acta pharmacologica Sinica 20080601
Catalase and epoxidation activity of manganese salen complexes bearing two xanthene scaffolds. Journal of the American Chemical Society 20070704
alpha-Lipoic acid and glutathione protect against the prooxidant activity of SOD/catalase mimetic manganese salen derivatives. Journal of inorganic biochemistry 20070201
Enhanced catalase-like activity of manganese salen complexes in water: effect of a three-dimensionally fixed auxiliary. Chemical communications (Cambridge, England) 20061221
Mechanisms of cell death of neural progenitor cells caused by trophic support deprivation. European journal of pharmacology 20061024
Pharmacology of delayed aging and extended lifespan of Caenorhabditis elegans. Experimental gerontology 20061001
Albumin-bound fatty acids induce mitochondrial oxidant stress and impair antioxidant responses in proximal tubular cells. Kidney international 20060801
Differential effects of salen and manganese-salen complex (EUK-8) on the regulation of cellular cadmium uptake and toxicity. Toxicological sciences : an official journal of the Society of Toxicology 20050501
A site-selective dual anchoring strategy for artificial metalloprotein design. Journal of the American Chemical Society 20040908
Superoxide dismutase mimetics elevate superoxide dismutase activity in vivo but do not retard aging in the nematode Caenorhabditis elegans. Free radical biology & medicine 20040715
Cardioprotection by chronic estrogen or superoxide dismutase mimetic treatment in the aged female rat. American journal of physiology. Heart and circulatory physiology 20040701
Bioconjugates of cyclodextrins of manganese salen-type ligand with superoxide dismutase activity. Journal of inorganic biochemistry 20040601
(Salen)Mn-catalyzed epoxidation of alkenes: a two-zone process with different spin-state channels as suggested by DFT study. Organic letters 20040108
Free radical production by hydroxy-salen manganese complexes studied by ESR and XANES. Journal of inorganic biochemistry 20021125
Reactive oxygen species scavengers attenuate endotoxin-induced impairment of hypoxic pulmonary vasoconstriction in mice. Anesthesiology 20021101
Oxidation of nitric oxide by oxomanganese-salen complexes: a new mechanism for cellular protection by superoxide dismutase/catalase mimetics. The Biochemical journal 20020815
Synthesis and structure of poly(binaphthyl salen manganese complex) and its application to asymmetric epoxidation. Chirality 20020701
Asymmetric epoxidation using a singly-bound supported Katsuki-type (salen)Mn complex. Chemical communications (Cambridge, England) 20020421
Role of reactive oxygen species and NAD(P)H oxidase in alpha(1)-adrenoceptor signaling in adult rat cardiac myocytes. American journal of physiology. Cell physiology 20020401
Reactive oxygen species mediate amplitude-dependent hypertrophic and apoptotic responses to mechanical stretch in cardiac myocytes. Circulation research 20010831
Reduced sarco/endoplasmic reticulum Ca(2+) uptake activity can account for the reduced response to NO, but not sodium nitroprusside, in hypercholesterolemic rabbit aorta. Circulation 20010828
(Salen)Mn(III)-catalyzed epoxidation reaction as a multichannel process with different spin states. Electronic tuning of asymmetric catalysis: a theoretical study. Inorganic chemistry 20010730
Salen complexes with bulky substituents as useful tools for biomimetic phenol oxidation research. Bioorganic & medicinal chemistry 20010601
Antioxidant treatment induces transcription and expression of transforming growth factor beta in cultured renal proximal tubular cells. FEBS letters 20010119
Reactive oxygen species mediate alpha-adrenergic receptor-stimulated hypertrophy in adult rat ventricular myocytes. Journal of molecular and cellular cardiology 20010101
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