Home Other Building Blocks AMCINONIDE

AMCINONIDE

CAS No.:
51022-69-6
Catalog Number:
AG00DA2D
Molecular Formula:
C28H35FO7
Molecular Weight:
502.5717
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
50mg
≥98%
1 week
United States
$91
- +
100mg
≥98%
1 week
United States
$119
- +
250mg
≥98%
1 week
United States
$187
- +
500mg
≥98%
1 week
United States
$300
- +
Product Description
Catalog Number:
AG00DA2D
Chemical Name:
AMCINONIDE
CAS Number:
51022-69-6
Molecular Formula:
C28H35FO7
Molecular Weight:
502.5717
MDL Number:
MFCD00213379
IUPAC Name:
[2-[(1S,2S,4R,8S,9S,11S,12R,13S)-12-fluoro-11-hydroxy-9,13-dimethyl-16-oxospiro[5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-diene-6,1'-cyclopentane]-8-yl]-2-oxoethyl] acetate
InChI:
InChI=1S/C28H35FO7/c1-16(30)34-15-22(33)28-23(35-26(36-28)9-4-5-10-26)13-20-19-7-6-17-12-18(31)8-11-24(17,2)27(19,29)21(32)14-25(20,28)3/h8,11-12,19-21,23,32H,4-7,9-10,13-15H2,1-3H3/t19-,20-,21-,23+,24-,25-,27-,28+/m0/s1
InChI Key:
ILKJAFIWWBXGDU-MOGDOJJUSA-N
SMILES:
CC(=O)OCC(=O)[C@@]12OC3(O[C@@H]1C[C@@H]1[C@]2(C)C[C@H](O)[C@]2([C@H]1CCC1=CC(=O)C=C[C@]21C)F)CCCC3
EC Number:
256-915-2
UNII:
423W026MA9
Properties
Complexity:
1090  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
8  
Defined Bond Stereocenter Count:
0
Exact Mass:
502.237g/mol
Formal Charge:
0
Heavy Atom Count:
36  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
502.579g/mol
Monoisotopic Mass:
502.237g/mol
Rotatable Bond Count:
4  
Topological Polar Surface Area:
99.1A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
3.6  
Literature
Title Journal
Identification and characterization of triamcinolone acetonide, a microglial-activation inhibitor. Immunopharmacology and immunotoxicology 20121201
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). PLoS computational biology 20111201
Atopic dermatitis. Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 20110101
Contact allergy to topical corticosteroids--results from the IVDK and epidemiological risk assessment. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20090101
Allergic contact dermatitis to topical drugs--epidemiological risk assessment. Pharmacoepidemiology and drug safety 20080801
Human receptor kinetics and lung tissue retention of the enhanced-affinity glucocorticoid fluticasone furoate. Respiratory research 20070101
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Angioedema and dysphagia caused by contact allergy to inhaled budesonide. Contact dermatitis 20030801
Selective corticosteroid injection into the extensor pollicis brevis tenosynovium for de Quervain's disease. Orthopedics 20020101
Exacerbation of allergic contact dermatitis from amcinonide triggered by patch testing. Contact dermatitis 20011001
Patch testing with serial dilutions of budesonide, its R and S diastereomers, and potentially cross-reacting substances. American journal of contact dermatitis : official journal of the American Contact Dermatitis Society 20010901
Tixocortol pivalate contact allergy in the GPMT: frequency and cross-reactivity. Contact dermatitis 20010101
Delayed generalized allergic reactions to corticosteroids. Dermatology (Basel, Switzerland) 20000101
Studies in patients with corticosteroid contact allergy. Understanding cross-reactivity among different steroids. Archives of dermatology 19950101
Contact sensitivity and cross-reactivity of budesonide. Contact dermatitis 19930401
Contact allergies to topical corticosteroids. Contact dermatitis 19930301
[Contact allergy to topical glucocorticoids]. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 19930201
Contact allergies to topical corticosteroids: 10 cases of contact dermatitis. Contact dermatitis 19910801
Influence of depigmenting chemical agents on hair and skin color in yellow (pheomelanic) and black (eumelanic) mice. Pigment cell research 19900101
Allergic contact dermatitis from topical corticosteroids. Contact dermatitis 19890801
Investigations on the development and regression of corticosteroid-induced thinning of the skin in various parts of the human body during and after topical application of amcinonide. Dermatologica 19890101
Amcinonide vs. betamethasone dipropionate ointments in the treatment of psoriasis. Cutis 19850501
Allergic contact dermatitis from amcinonide. Contact dermatitis 19850401
A comparative study of amcinonide and halcinonide in the treatment of eczematous dermatitis. Cutis 19840801
Allergy to 2 new corticoid molecules. Contact dermatitis 19840801
Contact sensitivity to topical corticosteroids. Journal of the American Academy of Dermatology 19840501
Comparison of amcinonide ointment 0.1 percent twice daily and fluocinonide ointment 0.05 percent three times daily in the treatment of psoriasis. Cutis 19830501
Treatment of psoriasis with amcinonide 0.1 percent and fluocinonide 0.05 percent ointments. A comparative double-blind study. Cutis 19820601
A controlled comparison of amcinonide cream 0.1 percent and halcinonide cream 0.1 percent in the treatment of eczematous dermatitis. Cutis 19811001
[Comparative pharmacological activity of triamcinolone acetonide and of a new topical steroid: amcinonide, after percutaneous or oral administration (author's transl)]. Journal de pharmacologie 19800101
Management of eczematous dermatitis with amcinonide or betamethasone valerate. A double-blind comparative study. Cutis 19791201
Properties