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Ginkgetin

CAS No.:
481-46-9
Catalog Number:
AG00D9XO
Molecular Formula:
C32H22O10
Molecular Weight:
566.5111
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
99%
1 week
United States
$473
- +
10mg
99%
1 week
United States
$757
- +
Product Description
Catalog Number:
AG00D9XO
Chemical Name:
Ginkgetin
CAS Number:
481-46-9
Molecular Formula:
C32H22O10
Molecular Weight:
566.5111
MDL Number:
MFCD09970948
IUPAC Name:
5,7-dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxochromen-2-yl)-2-methoxyphenyl]-2-(4-hydroxyphenyl)chromen-4-one
InChI:
InChI=1S/C32H22O10/c1-39-18-10-20(34)30-23(37)13-27(41-28(30)11-18)16-5-8-25(40-2)19(9-16)29-21(35)12-22(36)31-24(38)14-26(42-32(29)31)15-3-6-17(33)7-4-15/h3-14,33-36H,1-2H3
InChI Key:
AIFCFBUSLAEIBR-UHFFFAOYSA-N
SMILES:
COc1ccc(cc1c1c(O)cc(c2c1oc(cc2=O)c1ccc(cc1)O)O)c1cc(=O)c2c(o1)cc(cc2O)OC
Properties
Complexity:
1080  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
566.121g/mol
Formal Charge:
0
Heavy Atom Count:
42  
Hydrogen Bond Acceptor Count:
10  
Hydrogen Bond Donor Count:
4  
Isotope Atom Count:
0
Molecular Weight:
566.518g/mol
Monoisotopic Mass:
566.121g/mol
Rotatable Bond Count:
5  
Topological Polar Surface Area:
152A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
5.7  
Literature
Title Journal
Neuroprotective effects of ginkgetin against neuroinjury in Parkinson's disease model induced by MPTP via chelating iron. Free radical research 20150101
Flavonoid dimers as novel, potent antileishmanial agents. Journal of medicinal chemistry 20121025
Antioxidant, antibacterial, cytotoxic, and apoptotic activity of stem bark extracts of Cephalotaxus griffithii Hook. f. BMC complementary and alternative medicine 20120101
Biflavonoids from Caper (Capparis spinosa L.) fruits and their effects in inhibiting NF-kappa B activation. Journal of agricultural and food chemistry 20110413
Target-guided isolation and purification of antioxidants from Selaginella sinensis by offline coupling of DPPH-HPLC and HSCCC experiments. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110115
The biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's disease. International journal of molecular sciences 20110101
Research strategies in the study of the pro-oxidant nature of polyphenol nutraceuticals. Journal of toxicology 20110101
Systematic review of herbals as potential anti-inflammatory agents: Recent advances, current clinical status and future perspectives. Pharmacognosy reviews 20110101
Biflavonoids from Torreya nucifera displaying SARS-CoV 3CL(pro) inhibition. Bioorganic & medicinal chemistry 20101115
A new dilactone from the seeds of Gaultheria yunnanensis. Fitoterapia 20100101
[Structrue identification of biflavones and determination of Taxol from Taxus Madia]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20081001
Biochemical pharmacology of biflavonoids: implications for anti-inflammatory action. Archives of pharmacal research 20080301
Seco-terpenoids and other constituents from Elateriospermum tapos. Journal of natural products 20080201
COX-2 inhibitor celecoxib prevents chronic morphine-induced promotion of angiogenesis, tumour growth, metastasis and mortality, without compromising analgesia. British journal of cancer 20071203
Anti-influenza virus activity of biflavonoids. Bioorganic & medicinal chemistry letters 20070201
Anti-inflammatory activity of the synthetic C-C biflavonoids. The Journal of pharmacy and pharmacology 20061201
Osteoblast differentiation stimulating activity of biflavonoids from Cephalotaxus koreana. Bioorganic & medicinal chemistry letters 20060601
Effects of anti-inflammatory biflavonoid, ginkgetin, on chronic skin inflammation. Biological & pharmaceutical bulletin 20060501
Inhibition of cGMP-phosphodiesterase-5 by biflavones of Ginkgo biloba. Planta medica 20060401
Biflavonoids inhibited phosphatase of regenerating liver-3 (PRL-3). Natural product research 20060401
Comparative antiplasmodial, leishmanicidal and antitrypanosomal activities of several biflavonoids. Phytomedicine : international journal of phytotherapy and phytopharmacology 20060201
Ginkgetin, a Biflavone from Ginko biloba leaves, inhibits cyclooxygenases-2 and 5-lipoxygenase in mouse bone marrow-derived mast cells. Biological & pharmaceutical bulletin 20051201
Biflavone glucosides from Ginkgo biloba yellow leaves. Chemical & pharmaceutical bulletin 20050901
Biflavonoids from Brazilian pine Araucaria angustifolia as potentials protective agents against DNA damage and lipoperoxidation. Phytochemistry 20050901
Neuroprotective effects of naturally occurring biflavonoids. Bioorganic & medicinal chemistry letters 20050801
Biflavones from Chamaecyparis obtusa. Zeitschrift fur Naturforschung. C, Journal of biosciences 20050101
Flavonoids from Metasequoia glyptostroboides. Acta poloniae pharmaceutica 20040101
[The effects of ginaton on cochlear microcirculation]. Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology 20030501
Antifungal activity of biflavones from Taxus baccata and Ginkgo biloba. Zeitschrift fur Naturforschung. C, Journal of biosciences 20030101
Effects of Ginkgetin from Ginkgo biloba Leaves on cyclooxygenases and in vivo skin inflammation. Planta medica 20020401
Biflavones of Ginkgo biloba stimulate lipolysis in 3T3-L1 adipocytes. Planta medica 20020101
Flavonoids differentially inhibit guinea pig epidermal cytosolic phospholipase A2. Prostaglandins, leukotrienes, and essential fatty acids 20010101
Studies on the cytotoxic mechanisms of ginkgetin in a human ovarian adenocarcinoma cell line. Naunyn-Schmiedeberg's archives of pharmacology 20000701
Mechanism of action of the antiherpesvirus biflavone ginkgetin. Antimicrobial agents and chemotherapy 19920901
Properties