Home Other Building Blocks 2-(1,3-Dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)acetic acid

2-(1,3-Dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)acetic acid

CAS No.:
51411-04-2
Catalog Number:
AG00D9WS
Molecular Formula:
C14H9NO4
Molecular Weight:
255.2256
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
98+%
1 week
United States
$127
- +
10mg
98+%
1 week
United States
$164
- +
50mg
99%
1 week
United States
$404
- +
100mg
99%
1 week
United States
$682
- +
500mg
99%
1 week
United States
$2210
- +
Product Description
Catalog Number:
AG00D9WS
Chemical Name:
2-(1,3-Dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)acetic acid
CAS Number:
51411-04-2
Molecular Formula:
C14H9NO4
Molecular Weight:
255.2256
MDL Number:
MFCD00181399
IUPAC Name:
2-(1,3-dioxobenzo[de]isoquinolin-2-yl)acetic acid
InChI:
InChI=1S/C14H9NO4/c16-11(17)7-15-13(18)9-5-1-3-8-4-2-6-10(12(8)9)14(15)19/h1-6H,7H2,(H,16,17)
InChI Key:
GCUCIFQCGJIRNT-UHFFFAOYSA-N
SMILES:
OC(=O)Cn1c(=O)c2cccc3c2c(c1=O)ccc3
UNII:
515DHK15LG
Properties
Complexity:
403  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
255.053g/mol
Formal Charge:
0
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
255.229g/mol
Monoisotopic Mass:
255.053g/mol
Rotatable Bond Count:
2  
Topological Polar Surface Area:
74.7A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.7  
Literature
Title Journal
Copper(II) carboxylate dimers prepared from ligands designed to form a robust π···π stacking synthon: supramolecular structures and molecular properties. Inorganic chemistry 20120116
The Prostaglandin F Synthase Activity of the Human Aldose Reductase AKR1B1 Brings New Lenses to Look at Pathologic Conditions. Frontiers in pharmacology 20120101
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. Bioorganic & medicinal chemistry letters 20101101
Diabetic cataract-pathogenesis, epidemiology and treatment. Journal of ophthalmology 20100101
Advances in pharmacological strategies for the prevention of cataract development. Indian journal of ophthalmology 20090101
Mechanism of high glucose induced angiotensin II production in rat vascular smooth muscle cells. Circulation research 20070831
Upregulation of aldose reductase by homocysteine in type II alveolar epithelial cells. Biochemical and biophysical research communications 20051202
Proteomic analysis of oxidative stress-resistant cells: a specific role for aldose reductase overexpression in cytoprotection. Molecular & cellular proteomics : MCP 20040201
Neonicotinoid insecticides: reduction and cleavage of imidacloprid nitroimine substituent by liver microsomal and cytosolic enzymes. Chemical research in toxicology 20020901
Impairment of type III group B Streptococcus-stimulated superoxide production and opsonophagocytosis by neutrophils in diabetes. Molecular genetics and metabolism 20010701
Aldose reductase inhibitors: a potential new class of agents for the pharmacological control of certain diabetic complications. Journal of medicinal chemistry 19850701
N-[5-(trifluoromethyl)-6-methoxy-1-naphthalenyl]thioxomethyl]- N-methylglycine (Tolrestat), a potent, orally active aldose reductase inhibitor. Journal of medicinal chemistry 19840301
Properties