Home Other Building Blocks 2-PHENYLAMINOADENOSINE

2-PHENYLAMINOADENOSINE

CAS No.:
53296-10-9
Catalog Number:
AG00D9QO
Molecular Formula:
C16H18N6O4
Molecular Weight:
358.3519
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Product Description
Catalog Number:
AG00D9QO
Chemical Name:
2-PHENYLAMINOADENOSINE
CAS Number:
53296-10-9
Molecular Formula:
C16H18N6O4
Molecular Weight:
358.3519
MDL Number:
MFCD00055119
IUPAC Name:
(2R,3R,4S,5R)-2-(6-amino-2-anilinopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
InChI:
InChI=1S/C16H18N6O4/c17-13-10-14(21-16(20-13)19-8-4-2-1-3-5-8)22(7-18-10)15-12(25)11(24)9(6-23)26-15/h1-5,7,9,11-12,15,23-25H,6H2,(H3,17,19,20,21)/t9-,11-,12-,15-/m1/s1
InChI Key:
SCNILGOVBBRMBK-SDBHATRESA-N
SMILES:
OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1nc(Nc1ccccc1)nc2N
UNII:
K40I59G1EF
Properties
Complexity:
482  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Defined Bond Stereocenter Count:
0
Exact Mass:
358.139g/mol
Formal Charge:
0
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
5  
Isotope Atom Count:
0
Molecular Weight:
358.358g/mol
Monoisotopic Mass:
358.139g/mol
Rotatable Bond Count:
4  
Topological Polar Surface Area:
152A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.8  
Literature
Title Journal
Adenosine A2A receptor as a drug discovery target. Journal of medicinal chemistry 20140508
Afferent arteriolar vasodilator effect of adenosine predominantly involves adenosine A2B receptor activation. American journal of physiology. Renal physiology 20100801
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nature chemical biology 20091001
Determination of adenosine effects and adenosine receptors in murine corpus cavernosum. The Journal of pharmacology and experimental therapeutics 20070801
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. The Journal of biological chemistry 20020419
Differences in the order of potency for agonists but not antagonists at human and rat adenosine A2A receptors. Biochemical pharmacology 19990101
Characterization of human A2A adenosine receptors with the antagonist radioligand [3H]-SCH 58261. British journal of pharmacology 19970501
Further confirmation of the role of adenyl cyclase and of cAMP-dependent protein kinase in primary afferent hyperalgesia. Neuroscience 19910101
Hemodynamic effects of adenosine agonists in the conscious spontaneously hypertensive rat. The Journal of pharmacology and experimental therapeutics 19900901
Comparison of the behavioral effects of adenosine agonists and dopamine antagonists in mice. Psychopharmacology 19890101
Effect of 2-phenylaminoadenosine (CV-1808) on ischemic ST-segment elevation in anesthetized dogs. Journal of cardiovascular pharmacology 19810101
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