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ZERANOL

CAS No.:
55331-29-8
Catalog Number:
AG00D92A
Molecular Formula:
Molecular Weight:
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Purity
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Product Description
Catalog Number:
AG00D92A
Chemical Name:
ZERANOL
CAS Number:
55331-29-8
MDL Number:
MFCD00864182
IUPAC Name:
8,16,18-trihydroxy-4-methyl-3-oxabicyclo[12.4.0]octadeca-1(14),15,17-trien-2-one
InChI:
InChI=1S/C18H26O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h10-12,14,19-21H,2-9H2,1H3
InChI Key:
DWTTZBARDOXEAM-UHFFFAOYSA-N
EC Number:
247-769-0
RTECS Number:
DM2520000
Properties
Complexity:
372  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
322.178g/mol
Formal Charge:
0
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
322.401g/mol
Monoisotopic Mass:
322.178g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
87A^2
Undefined Atom Stereocenter Count:
2  
Undefined Bond Stereocenter Count:
0
XLogP3:
4.3  
Literature
Title Journal
Zeranol induces COX-2 expression through TRPC-3 activation in the placental cells JEG-3. Toxicology in vitro : an international journal published in association with BIBRA 20160901
Activation of ER stress and apoptosis by α- and β-zearalenol in HCT116 cells, protective role of Quercetin. Neurotoxicology 20160301
Effect of zeranol on expression of apoptotic and cell cycle proteins in murine placentae. Toxicology 20131206
Zeranol upregulates corticotropin releasing hormone expression in the placental cell line JEG-3. Toxicology letters 20130607
Cellular mechanisms of the cytotoxic effects of the zearalenone metabolites α-zearalenol and β-zearalenol on RAW264.7 macrophages. Toxicology in vitro : an international journal published in association with BIBRA 20130401
Changes in intramuscular fat, fatty acid profile and cholesterol content induced by zeranol implantation strategy in hair lambs. Journal of the science of food and agriculture 20120501
Catechol metabolites of zeranol and 17β-estradiol: a comparative in vitro study on the induction of oxidative DNA damage and methylation by catechol-O-methyltransferase. Toxicology letters 20120405
In vitro effects of some anabolic compounds on erythrocyte carbonic anhydrase I and II. Journal of enzyme inhibition and medicinal chemistry 20120401
Liquid chromatography incorporating ultraviolet and electrochemical analyses for dual detection of zeranol and zearalenone metabolites in mouldy grains. Journal of the science of food and agriculture 20120401
A fungal ketoreductase domain that displays substrate-dependent stereospecificity. Nature chemical biology 20120401
In vitro toxicological effects of estrogenic mycotoxins on human placental cells: structure activity relationships. Toxicology and applied pharmacology 20120315
The role of α-zearalanol in reversing bone loss induced by ovarian hormone deficiency in rats. Journal of bone and mineral metabolism 20120301
Prediction and experimental evaluation of soil sorption by natural hormones and hormone mimics. Journal of agricultural and food chemistry 20120215
Effect of growth promotants on the occurrence of endogenous and synthetic steroid hormones on feedlot soils and in runoff from beef cattle feeding operations. Environmental science & technology 20120207
Preparation of highly specific anti-zearalenone antibodies by using the cationic protein conjugate and development of an indirect competitive enzyme-linked immunosorbent assay. The Analyst 20120107
Cytosol protein regulation in H295R steroidogenesis model induced by the zearalenone metabolites, α- and β-zearalenol. Toxicon : official journal of the International Society on Toxinology 20120101
ZEN and the art of breast health maintenance. International journal of clinical practice 20120101
Prediction of ligand binding affinity using a multiple-conformations-multiple-protonation scheme: application to estrogen receptor α. Chemical & pharmaceutical bulletin 20120101
Mycotoxin alpha-zearalenol impairs the quality of preimplantation porcine embryos. The Journal of reproduction and development 20120101
The neuroprotective effects of phytoestrogen α-zearalanol on β-amyloid-induced toxicity in differentiated PC-12 cells. European journal of pharmacology 20111130
In vitro and in vivo induction of chromosome aberrations by alpha- and beta-zearalenols: comparison with zearalenone. Mutation research 20111127
Urinary mycoestrogens, body size and breast development in New Jersey girls. The Science of the total environment 20111115
Simultaneous LC-MS/MS determination of aflatoxin M1, ochratoxin A, deoxynivalenol, de-epoxydeoxynivalenol, α and β-zearalenols and fumonisin B1 in urine as a multi-biomarker method to assess exposure to mycotoxins. Analytical and bioanalytical chemistry 20111101
Endocrine disrupting effects of zearalenone, alpha- and beta-zearalenol at the level of nuclear receptor binding and steroidogenesis. Toxicology letters 20111010
Determination of zearalenone and its metabolites in endometrial cancer by coupled separation techniques. Analytical and bioanalytical chemistry 20111001
Zeranol induces cell proliferation and protein disulfide isomerase expression in mammary gland of ACI rat. Anticancer research 20110501
Detection of zearalenone and its metabolites in naturally contaminated porcine follicular fluid by using liquid chromatography-tandem mass spectrometry. The Journal of reproduction and development 20110401
Phytoestrogen α-zearalanol improves vascular function in ovariectomized hyperhomocysteinemic rats. Atherosclerosis 20110401
In vitro transformation of MCF-10A cells by sera harvested from heifers two months post-Zeranol implantation. International journal of oncology 20110401
Absorption and metabolism of the mycotoxin zearalenone and the growth promotor zeranol in Caco-2 cells in vitro. Molecular nutrition & food research 20110401
A rapid method for simultaneous determination of zearalenone, α-zearalenol, β-zearalenol, zearalanone, α-zearalanol and β-zearalanol in traditional Chinese medicines by ultra-high-performance liquid chromatography-tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110215
Serum derived from zeranol-implanted ACI rats promotes the growth of human breast cancer cells in vitro. Anticancer research 20110201
Application of cytochrome P450 BM3 mutants as biocatalysts for the profiling of estrogen receptor binding metabolites of the mycotoxin zearalenone. Xenobiotica; the fate of foreign compounds in biological systems 20110101
Zeranol down-regulates p53 expression in primary cultured human breast cancer epithelial cells through epigenetic modification. International journal of molecular sciences 20110101
Hapten-antibody recognition studies in competitive immunoassay of α-zearalanol analogs by computational chemistry and Pearson Correlation analysis. Journal of molecular recognition : JMR 20110101
Dose-response effects of estrogenic mycotoxins (zearalenone, alpha- and beta-zearalenol) on motility, hyperactivation and the acrosome reaction of stallion sperm. Reproductive biology and endocrinology : RB&E 20110101
Zeranol: doping offence or mycotoxin? A case-related study. Drug testing and analysis 20110101
Insights into radicicol biosynthesis via heterologous synthesis of intermediates and analogs. The Journal of biological chemistry 20101231
Aromatase expression in leptin-pretreated human breast pre-adipocytes is enhanced by zeranol and suppressed by (-)-gossypol. Anticancer research 20101201
Effects of oral exposure of pigs to deoxynivalenol (DON) sulfonate (DONS) as the non-toxic derivative of DON on tissue residues of DON and de-epoxy-DON and on DONS blood levels. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20101101
[Effect of zeranol on spermary and spermigenesis function of male mice]. Wei sheng yan jiu = Journal of hygiene research 20101101
Glucuronidation of zearalenone, zeranol and four metabolites in vitro: formation of glucuronides by various microsomes and human UDP-glucuronosyltransferase isoforms. Molecular nutrition & food research 20101001
Zearalenone is bioactivated in the river Buffalo (Bubalus bubalis): hepatic biotransformation. Tropical animal health and production 20100801
Oestrogenic mycotoxin exposures and precocious pubertal development. International journal of andrology 20100401
Metabolic conversion of zearalenone to alpha-zearalenol by goat tissues. The Journal of veterinary medical science 20100301
Aromatic hydroxylation and catechol formation: a novel metabolic pathway of the growth promotor zeranol. Toxicology letters 20100215
The effects of α-zearalanol and estradiol benzoate on expression of c-myc, c-fos and epidermal growth factor receptor mRNAs in breast tissues implanted into nude mice. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20100201
[Effect of alpha-zearalanol upon the expression of HO-1 gene and the cytosolic free calcium level in tumor necrosis factor alpha-stimulated human endothelial cell]. Zhonghua yi xue za zhi 20091215
A stable fish reporter cell line to study estrogen receptor transactivation by environmental (xeno)estrogens. Toxicology in vitro : an international journal published in association with BIBRA 20091201
Zeranol enhances the proliferation of pre-adipocytes in beef heifers. Anticancer research 20091201
Mitogenic activity of zeranol in human breast cancer cells is enhanced by leptin and suppressed by gossypol. Anticancer research 20091101
Comparison of chemical binding to recombinant fathead minnow and human estrogen receptors alpha in whole cell and cell-free binding assays. Environmental toxicology and chemistry 20091001
Quantitative screening of stilbenes and zeranol and its related residues and natural precursors in veal liver by gas chromatography-mass spectrometry. Journal of agricultural and food chemistry 20090812
Relaxing effects of phytoestrogen alpha-zearalanol on rat thoracic aorta rings in vitro. The Chinese journal of physiology 20090430
Confirmatory method for the determination of resorcylic acid lactones in urine sample using immunoaffinity cleanup and liquid chromatography-tandem mass spectrometry. Analytica chimica acta 20090401
Ultra-high-pressure liquid chromatography-tandem mass spectrometry for the analysis of six resorcylic acid lactones in bovine milk. Journal of chromatography. A 20090320
Effects of zearalenone and alpha-Zearalenol in comparison with Raloxifene on T47D cells. Toxicology mechanisms and methods 20090301
[Effect of alpha-zearalanol on the generation of reactive oxygen species (ROS) and ROS-activated signal transduction in tumor necrosis factor alpha-stimulated human endothelial cells]. Zhonghua yi xue za zhi 20090203
Screening and confirmatory methods for the analysis of macrocyclic lactone mycotoxins by CE with amperometric detection. Electrophoresis 20090201
Preparation and characterization of the conjugated Fusarium mycotoxins zearalenone-4O-beta-D-glucopyranoside, alpha-zearalenol-4O-beta-D-glucopyranoside and beta-zearalenol-4O-beta-D-glucopyranoside by MS/MS and two-dimensional NMR. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20090201
Comparative study of toxic effects of zearalenone and its two major metabolites alpha-zearalenol and beta-zearalenol on cultured human Caco-2 cells. Journal of biochemical and molecular toxicology 20090101
Cytotoxicity effects induced by Zearalenone metabolites, alpha Zearalenol and beta Zearalenol, on cultured Vero cells. Toxicology 20081030
Immune effects of four Fusarium-toxins (FB1, ZEA, NIV, DON) on the proliferation of Jurkat cells and porcine lymphocytes: in vitro study. Veterinary research communications 20080901
Direct determination of the estrogenic compounds 8-prenylnaringenin, zearalenone, alpha- and beta-zearalenol in beer by liquid chromatography-mass spectrometry. Journal of chromatography. A 20080815
Effects of Fusarium mycotoxins on steroid production by porcine granulosa cells. Animal reproduction science 20080801
Influence of in vitro exposure to mycotoxin zearalenone and its derivatives on swine sperm quality. Reproductive toxicology (Elmsford, N.Y.) 20080801
alpha-Zearalanol attenuates oxLDL-induced ET-1 gene expression, ET-1 secretion and redox-sensitive intracellular signaling activation in human umbilical vein endothelial cells. Toxicology letters 20080710
Evaluation of zearalenone and alpha-zearalenol toxicity on boar sperm DNA integrity. Journal of applied toxicology : JAT 20080701
Effects of four Fusarium toxins (fumonisin B(1), alpha-zearalenol, nivalenol and deoxynivalenol) on porcine whole-blood cellular proliferation. Toxicon : official journal of the International Society on Toxinology 20080701
High growth rate of girls with precocious puberty exposed to estrogenic mycotoxins. The Journal of pediatrics 20080501
Phytoestrogen alpha-zearalanol inhibits homocysteine-induced endothelin-1 expression and oxidative stress in human umbilical vein endothelial cells. Atherosclerosis 20080401
The environmental impact of growth-promoting compounds employed by the United States beef cattle industry: history, current knowledge, and future directions. Reviews of environmental contamination and toxicology 20080101
Development and evaluation of immunoassay for zeranol in bovine urine. Journal of Zhejiang University. Science. B 20071201
Protective effects of phytoestrogen alpha-zearalanol on beta amyloid25-35 induced oxidative damage in cultured rat hippocampal neurons. Endocrine 20071001
Survey of maize from south-western Nigeria for zearalenone, alpha- and beta-zearalenols, fumonisin B1 and enniatins produced by Fusarium species. Food additives and contaminants 20070901
Novel oxidative metabolites of the mycoestrogen zearalenone in vitro. Molecular nutrition & food research 20070701
Effects of Zeranol upon luteal maintenance and fetal development in peripubertal gilts. Animal reproduction science 20070601
Toxic effects of zearalenone and alpha-zearalenol on the regulation of steroidogenesis and testosterone production in mouse Leydig cells. Toxicology in vitro : an international journal published in association with BIBRA 20070601
Analytical methods for the determination of zeranol residues in animal products: a review. Food additives and contaminants 20070601
Modification of mRNA expression after treatment with anabolic agents and the usefulness for gene expression-biomarkers. Analytica chimica acta 20070314
Comparison of the molecular effects of the mycotoxins beta-zearalenol and deoxynivalenol in porcine endometrial cells--a review. Acta veterinaria Hungarica 20070301
Determination of trichothecenes, zearalenone and zearalenols in commercially available corn-based foods in Spain. Revista iberoamericana de micologia 20070301
Characterization of the estrogenic activities of zearalenone and zeranol in vivo and in vitro. The Journal of steroid biochemistry and molecular biology 20070201
Quantification of estrogenic mycotoxins at the ng/L level in aqueous environmental samples using deuterated internal standards. Journal of chromatography. A 20070105
[Preparation and preliminary application of monoclonal antibody against alpha-zearalanol]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20070101
Visual documentation of ovine pituitary gland development with magnetic resonance imaging following zeranol treatment. Laboratory animals 20070101
Primary cultured human breast epithelial cells up-regulate protein disulfide isomerase in response to zeranol. Anticancer research 20070101
Study on the in vitro effect of zearalenone and alpha-zearalenol on boar sperm-zona pellucida interaction by hemizona assay application. Journal of applied toxicology : JAT 20070101
Toxic effects of zearalenone and its derivatives alpha-zearalenol on male reproductive system in mice. Reproductive toxicology (Elmsford, N.Y.) 20070101
Determination of the cross-reactivities for alpha-zearalenol, beta-zearalenol, zearalanone, alpha-zearalanol, and beta-zearalanol on three commercial immunoaffinity columns targeting zearalenone. Journal of AOAC International 20070101
Interactive effects of fumonisin B1 and alpha-zearalenol on proliferation and cytokine expression in Jurkat T cells. Toxicology in vitro : an international journal published in association with BIBRA 20061201
Biphasic effects of zeranol on the growth of estrogen receptor-positive human breast carcinoma cells. Oncology reports 20061201
Treatment with phytoestrogen alpha-zearalanol might protect neurons of hippocampus in ovariectomized rats. Endocrine 20061201
In vitro effect of zearalenone and alpha-zearalenol on boar sperm characteristics and acrosome reaction. Reproduction in domestic animals = Zuchthygiene 20061001
Molecularly imprinted polymers applied to the clean-up of zearalenone and alpha-zearalenol from cereal and swine feed sample extracts. Analytical and bioanalytical chemistry 20060801
Hydroxysteroid dehydrogenases in bovine and porcine granulosa cells convert zearalenone into its hydroxylated metabolites alpha-zearalenol and beta-zearalenol. Veterinary research communications 20060501
Determination of resorcylic acid lactones in biological samples by GC-MS. Discrimination between illegal use and contamination with fusarium toxins. Analytical and bioanalytical chemistry 20060301
Phytoestrogen alpha-zearalanol antagonizes homocysteine-induced imbalance of nitric oxide/endothelin-1 and apoptosis in human umbilical vein endothelial cells. Cell biochemistry and biophysics 20060101
Influence of mycotoxin zearalenone and its derivatives (alpha and beta zearalenol) on apoptosis and proliferation of cultured granulosa cells from equine ovaries. Reproductive biology and endocrinology : RB&E 20060101
Multiresidue determination of zeranol and related compounds in bovine muscle by gas chromatography/mass spectrometry with immunoaffinity cleanup. Journal of AOAC International 20060101
Enzyme kinetics of zearalenone biotransformation: pH and cofactor effects. Archives of toxicology 20051001
Assessment of proliferative activity by AgNOR and PCNA in prostatic tissues of ram lambs implanted with zeranol. Reproduction in domestic animals = Zuchthygiene 20051001
Inhibitory effects of alpha-zearalenol on angiotensin II-induced integrin beta3 mRNA via suppression of nuclear factor-kappaB. Biomedical and environmental sciences : BES 20051001
Kinetics and metabolism of zearalenone in young female pigs. Journal of animal physiology and animal nutrition 20050801
Efficient decontamination of zearalenone, the mycotoxin of cereal pathogen, by transgenic yeasts through the expression of a synthetic lactonohydrolase gene. Applied microbiology and biotechnology 20050601
Degradation of estradiol and ethinyl estradiol by activated sludge and by a defined mixed culture. Applied microbiology and biotechnology 20050401
Effects of prepubertal exposure to xenoestrogen on development of estrogen target organs in female CD-1 mice. In vivo (Athens, Greece) 20050101
Level of zearalenone in blood serum and lesions in ovarian follicles of sexually immature gilts in the course of zearalenone micotoxicosis. Polish journal of veterinary sciences 20050101
Influence of the mycotoxins alpha- and beta-zearalenol (ZOL) on regulators of cap-dependent translation control in pig endometrial cells. Reproductive toxicology (Elmsford, N.Y.) 20041201
Phytoestrogen alpha-zearalanol antagonizes oxidized LDL-induced inhibition of nitric oxide production and stimulation of endothelin-1 release in human umbilical vein endothelial cells. Endocrine 20041201
Modeling correlated main-chain motions in proteins for flexible molecular recognition. Proteins 20041101
Alpha-Zearalanol, a phytoestrogen for cardiovascular therapy. Endocrine 20041101
Phytoestrogen alpha-zearalanol inhibits atherogenesis and improves lipid profile in ovariectomized cholesterol-fed rabbits. Endocrine 20041101
[Effects of phytoestrogen alpha-zearalanol on normal human breast]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20041001
Prevalence of zeranol, taleranol and Fusarium spp. toxins in urine: implications for the control of zeranol abuse in the European Union. Food additives and contaminants 20040901
Cytotoxicity, inhibition of DNA and protein syntheses and oxidative damage in cultured cells exposed to zearalenone. Toxicology in vitro : an international journal published in association with BIBRA 20040801
Effects of 17beta-estradiol and phytoestrogen alpha-zearalanol on tissue factor in plasma of ovariectomized rats and HUVECs. The Chinese journal of physiology 20040630
Comparison of cardiac contractile and intracellular Ca2+ response between estrogen and phytoestrogen alpha-zearalanol in ventricular myocytes. Endocrine 20040601
Function analysis of estrogenically regulated protein tyrosine phosphatase gamma (PTPgamma) in human breast cancer cell line MCF-7. Oncogene 20040212
Confirmatory assay for zeranol, taleranol and the Fusarium spp. toxins in bovine urine using liquid chromatography-tandem mass spectrometry. Food additives and contaminants 20040101
Transformation of MCF-10A human breast epithelial cells by zeranol and estradiol-17beta. The breast journal 20040101
Effects of prepubertal zeranol exposure on estrogen target organs and N-methyl-N-nitrosourea-induced mammary tumorigenesis in female Sprague-Dawley rats. In vivo (Athens, Greece) 20040101
The immune system of geriatric mice is modulated by estrogenic endocrine disruptors (diethylstilbestrol, alpha-zearalanol, and genistein): effects on interferon-gamma. Toxicology 20031215
Interlaboratory ring test of time-resolved fluoroimmunoassays for zeranol and alpha-zearalenol and comparison with zeranol test kits. Food additives and contaminants 20030901
Effect of some mycotoxins on superoxide anion production of isolated human neutrophils and in whole blood. Immunopharmacology and immunotoxicology 20030801
The influence of alpha-zearalenol on magnesium concentration in cellular subfractions of certain tissues of female rats and their progeny. Magnesium research 20030601
Body composition, leptin, and the leptin receptor and their relationship to the growth hormone (GH) axis in growing wethers treated with zeranol. Domestic animal endocrinology 20030401
[Determination of zearalenone and its metabolites in grains by capillary electrophoresis]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20030401
Phytoestrogens inhibit aromatase but not 17beta-hydroxysteroid dehydrogenase (HSD) type 1 in human granulosa-luteal cells: evidence for FSH induction of 17beta-HSD. Human reproduction (Oxford, England) 20030301
Effects of graded levels of Fusarium toxin-contaminated wheat and of a detoxifying agent in broiler diets on performance, nutrient digestibility and blood chemical parameters. British poultry science 20030301
The gastrointestinal tract as target of steroid hormone action: quantification of steroid receptor mRNA expression (AR, ERalpha, ERbeta and PR) in 10 bovine gastrointestinal tract compartments by kinetic RT-PCR. The Journal of steroid biochemistry and molecular biology 20030201
Effects of implant regimens (trenbolone acetate-estradiol administered alone or in combination with zeranol) and vitamin D3 on fresh beef color and quality. Journal of animal science 20030101
Influence of the mycotoxins alpha- and beta-zearalenol and deoxynivalenol on the cell cycle of cultured porcine endometrial cells. Reproductive toxicology (Elmsford, N.Y.) 20030101
Validation of screening method for residues of diethylstilbestrol, dienestrol, hexestrol, and zeranol in bovine urine using immunoaffinity chromatography and gas chromatography/mass spectrometry. Journal of AOAC International 20030101
Sample preparation for determination of macrocyclic lactone mycotoxins in fish tissue, based on on-line matrix solid-phase dispersion and solid-phase extraction cleanup followed by liquid chromatography/tandem mass spectrometry. Journal of AOAC International 20030101
Effects of the mycotoxins alpha- and beta-zearalenol on regulation of progesterone synthesis in cultured granulosa cells from porcine ovaries. Reproductive toxicology (Elmsford, N.Y.) 20030101
Influence of zearalenone on reproductive system cell proliferation in gilts. Polish journal of veterinary sciences 20030101
The influence of the mycotoxins deoxynivalenol and zearalenol on in vitro maturation of pig oocytes and in vitro culture of pig zygotes. Toxicology in vitro : an international journal published in association with BIBRA 20021201
Development and validation of dry reagent time-resolved fluoroimmunoassays for zeranol and alpha-zearalenol to assist in distinguishing zeranol abuse from Fusarium spp. toxin contamination in bovine urine. Food additives and contaminants 20021201
Metabolic profiles of the mycotoxin zearalenone and of the growth promoter zeranol in urine, liver, and muscle of heifers. Journal of agricultural and food chemistry 20020814
Quantitative assessment of foetal exposure to trenbolone acetate, zeranol and melengestrol acetate, following maternal dosing in rabbits. Xenobiotica; the fate of foreign compounds in biological systems 20020801
Effect of zeranol or melengestrol acetate (MGA) on testicular and antler development and aggression in farmed fallow bucks. Journal of animal science 20020601
Concentration levels of zearalenone and its metabolites in urine, muscle tissue, and liver samples of pigs fed with mycotoxin-contaminated oats. Journal of agricultural and food chemistry 20020424
Fusarium toxins in wheat flour collected in an area in southwest Germany. International journal of food microbiology 20020130
A specificity-enhanced time-resolved fluoroimmunoassay for zeranol employing the dry reagent all-in-one-well principle. The Analyst 20020101
Involvement of breast epithelial-stromal interactions in the regulation of protein tyrosine phosphatase-gamma (PTPgamma) mRNA expression by estrogenically active agents. Breast cancer research and treatment 20020101
Detection and identification of zeranol in chicken or rabbit liver by liquid chromatography-electrospray tandem mass spectrometry. Journal of AOAC International 20020101
Estrogenic down-regulation of protein tyrosine phosphatase gamma (PTP gamma) in human breast is associated with estrogen receptor alpha. Anticancer research 20020101
Reciprocal mutagenesis between human alpha(L349, M528) and rainbow trout (M317, I496) estrogen receptor residues demonstrates their importance in ligand binding and gene expression at different temperatures. Molecular and cellular endocrinology 20011025
[Simple and rapid analysis of trenbolone and zeranol residues in cattle muscle and liver by stack-cartridge solid-phase extraction and HPLC using on-line clean-up with EC and UV detection]. Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20010801
Assessment of oestrogenic potency of chemicals used as growth promoter by in-vitro methods. Human reproduction (Oxford, England) 20010501
Oestrogenic potencies of Zeranol, oestradiol, diethylstilboestrol, Bisphenol-A and genistein: implications for exposure assessment of potential endocrine disrupters. Human reproduction (Oxford, England) 20010501
Tissue-specific expression pattern of estrogen receptors (ER): quantification of ER alpha and ER beta mRNA with real-time RT-PCR. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20010501
Impact of doramectin treatment at the time of feedlot entry on the productivity of yearling steers with natural nematode infections. American journal of veterinary research 20010401
Agonistic and antagonistic effects of zearalenone, an etrogenic mycotoxin, on SKN, HHUA, and HepG2 human cancer cell lines. Veterinary and human toxicology 20010201
The phytoestrogen alpha-zearalenol reverses endothelial dysfunction induced by oophorectomy in rats. Laboratory investigation; a journal of technical methods and pathology 20010201
Genotoxic potential of xenobiotic growth promoters and their metabolites. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20010201
Development of an analytical system for the simultaneous determination of anabolic macrocyclic lactones in aquatic environmental samples. Rapid communications in mass spectrometry : RCM 20010101
Hormone contents in peripheral tissues after correct and off-label use of growth promoting hormones in cattle: effect of the implant preparations Filaplix-H, Raglo, Synovex-H and Synovex Plus. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20010101
Toxic effects of the mycotoxin zearalenone and its derivatives on in vitro maturation of bovine oocytes and 17 beta-estradiol levels in mural granulosa cell cultures. Toxicology in vitro : an international journal published in association with BIBRA 20010101
Excretion kinetics and metabolism of zearalenone in broilers in dependence on a detoxifying agent. Archiv fur Tierernahrung 20010101
Inhibitory effect of natural and environmental estrogens on thymic hormone production in thymus epithelial cell culture. International journal of immunopharmacology 19991201
Rapid inhibition of rat brain mitochondrial proton F0F1-ATPase activity by estrogens: comparison with Na+, K+ -ATPase of porcine cortex. European journal of pharmacology 19990226
Estrogen-induced hepatic toxicity and hepatic cancer: differences between two closely related hamster species. Liver 19981001
Epidemiological studies related to the use of hormonal agents in animal production. Environmental quality and safety. Supplement 19760101
Properties