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SUC-ALA-ALA-ALA-PNA

CAS No.:
52299-14-6
Catalog Number:
AG00D8ZJ
Molecular Formula:
C19H25N5O8
Molecular Weight:
451.4305
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Product Description
Catalog Number:
AG00D8ZJ
Chemical Name:
SUC-ALA-ALA-ALA-PNA
CAS Number:
52299-14-6
Molecular Formula:
C19H25N5O8
Molecular Weight:
451.4305
MDL Number:
MFCD00036774
IUPAC Name:
4-[[(2S)-1-[[(2S)-1-[[(2S)-1-(4-nitroanilino)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoic acid
InChI:
InChI=1S/C19H25N5O8/c1-10(20-15(25)8-9-16(26)27)17(28)21-11(2)18(29)22-12(3)19(30)23-13-4-6-14(7-5-13)24(31)32/h4-7,10-12H,8-9H2,1-3H3,(H,20,25)(H,21,28)(H,22,29)(H,23,30)(H,26,27)/t10-,11-,12-/m0/s1
InChI Key:
GVUGADOWXGKRAE-SRVKXCTJSA-N
SMILES:
O=C(N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)Nc1ccc(cc1)[N+](=O)[O-])C)C)C)CCC(=O)O
EC Number:
257-823-5
UNII:
9MJ6NSX3KJ
Properties
Complexity:
730  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
3  
Defined Bond Stereocenter Count:
0
Exact Mass:
451.17g/mol
Formal Charge:
0
Heavy Atom Count:
32  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
5  
Isotope Atom Count:
0
Molecular Weight:
451.436g/mol
Monoisotopic Mass:
451.17g/mol
Rotatable Bond Count:
10  
Topological Polar Surface Area:
200A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.4  
Literature
Title Journal
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Isolation and biochemical characterization of rubelase, a non-hemorrhagic elastase from Crotalus ruber ruber (Red Rattlesnake) venom. Toxins 20110701
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In situ and multisubstrate detection of elastase enzymatic activity external to microdialysis sampling probes using LC-ESI-MS. Analytical chemistry 20080315
In vitro characterization of an in situ microdialysis sampling assay for elastase activity detection. Journal of pharmaceutical and biomedical analysis 20060318
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Enhancement of apparent substrate selectivity of proteinase K encapsulated in liposomes through a cholate-induced alteration of the bilayer permeability. Biotechnology and bioengineering 20040120
Procerain, a stable cysteine protease from the latex of Calotropis procera. Phytochemistry 20030401
Anti-inflammatory effect of rutin on rat paw oedema, and on neutrophils chemotaxis and degranulation. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20030301
The third serine proteinase with chymotrypsin specificity isolated from Atlantic cod (Gadus morhua) is a type-II elastase. European journal of biochemistry 19980801
Purification and characterization of ovine pancreatic elastase. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 19980701
Development and in vitro evaluation of a drug delivery system based on chitosan-EDTA BBI conjugate. Journal of drug targeting 19980101
Cleavage specificity of cucumisin, a plant serine protease. Journal of biochemistry 19950501
Purification and characterization of a neutral zinc endopeptidase secreted by Flavobacterium meningosepticum. Archives of biochemistry and biophysics 19940515
A kinetic comparison of the homologous proteases astacin and meprin A. Archives of biochemistry and biophysics 19940401
Catalytic activity of elastase in reverse micelles. Biochemistry and molecular biology international 19931101
Properties of elastase from Atlantic cod, a cold-adapted proteinase. Biochimica et biophysica acta 19930624
Thiol containing compounds and amino acid hydroxamates as reversible synthetic inhibitors of Astacus protease. Archives of biochemistry and biophysics 19900901
Long-range structural changes in proteinase K triggered by calcium ion removal. Nature 19890202
Purification and characterization of aqualysin I (a thermophilic alkaline serine protease) produced by Thermus aquaticus YT-1. European journal of biochemistry 19880201
Interference of cartilage surface with interaction of granulocyte elastase with alpha 1-proteinase inhibitor. An in vitro model of enzyme inhibition in the joint space. Rheumatology international 19870101
Characterization of elastase associated with granulomatous tissue remodeling. Journal of cellular biochemistry 19860101
Properties