Home Aminos Cyclohexanepropanoic acid, a-amino-

Cyclohexanepropanoic acid, a-amino-

CAS No.:
4441-50-3
Catalog Number:
AG00D8IN
Molecular Formula:
C9H17NO2
Molecular Weight:
171.2368
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
Product Description
Catalog Number:
AG00D8IN
Chemical Name:
Cyclohexanepropanoic acid, a-amino-
CAS Number:
4441-50-3
Molecular Formula:
C9H17NO2
Molecular Weight:
171.2368
MDL Number:
MFCD01104092
IUPAC Name:
2-amino-3-cyclohexylpropanoic acid
InChI:
InChI=1S/C9H17NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h7-8H,1-6,10H2,(H,11,12)
InChI Key:
ORQXBVXKBGUSBA-UHFFFAOYSA-N
SMILES:
OC(=O)CCNC1CCCCC1
NSC Number:
12794
Properties
Complexity:
153  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
171.126g/mol
Formal Charge:
0
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
171.24g/mol
Monoisotopic Mass:
171.126g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
63.3A^2
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.3  
Literature
Title Journal
Creation of a thermostable NADP⁺-dependent D-amino acid dehydrogenase from Ureibacillus thermosphaericus strain A1 meso-diaminopimelate dehydrogenase by site-directed mutagenesis. Biotechnology letters 20120901
Experimental evaluation of CH-π interactions in a protein core. Chemistry (Weinheim an der Bergstrasse, Germany) 20120507
Role of amino acid hydrophobicity, aromaticity, and molecular volume on IAPP(20-29) amyloid self-assembly. Proteins 20120401
Characterization of new stable ghrelin analogs with prolonged orexigenic potency. The Journal of pharmacology and experimental therapeutics 20120301
Bifunctional μ/δ opioid peptides: variation of the type and length of the linker connecting the two components. Chemical biology & drug design 20120201
Radiolabelled peptides for oncological diagnosis. European journal of nuclear medicine and molecular imaging 20120201
Tuning β-sheet peptide self-assembly and hydrogelation behavior by modification of sequence hydrophobicity and aromaticity. Biomacromolecules 20110711
Probing phenylalanine environments in oligomeric structures with pentafluorophenylalanine and cyclohexylalanine. Biopolymers 20110601
Probing aromatic, hydrophobic, and steric effects on the self-assembly of an amyloid-β fragment peptide. Molecular bioSystems 20110201
Deletion of Ac-NMePhe(1) from [NMePhe(1) ]arodyn under acidic conditions, part 2: effects of substitutions on pharmacological activity. Biopolymers 20110101
Design of glycopeptides used to investigate class II MHC binding and T-cell responses associated with autoimmune arthritis. PloS one 20110101
A comparative study of the pharmacokinetics of traditional and automated dosing/blood sampling systems using gabapentin. Indian journal of pharmacology 20110101
The potential of antimicrobial peptides as biocides. International journal of molecular sciences 20110101
In vitro selection of a DNA-templated small-molecule library reveals a class of macrocyclic kinase inhibitors. Journal of the American Chemical Society 20100825
Cyanobacterial cyclopeptides as lead compounds to novel targeted cancer drugs. Marine drugs 20100101
Grifonin-1: a small HIV-1 entry inhibitor derived from the algal lectin, Griffithsin. PloS one 20100101
The effect of increasing hydrophobicity on the self-assembly of amphipathic beta-sheet peptides. Molecular bioSystems 20090901
Development of inhibitors against lipase and alpha-glucosidase from derivatives of monascus pigment. FEMS microbiology letters 20071101
Expression levels of adenosine receptors in hippocampus and frontal cortex in argyrophilic grain disease. Neuroscience letters 20070823
4-aminophenylalanine and 4-aminocyclohexylalanine derivatives as potent, selective, and orally bioavailable inhibitors of dipeptidyl peptidase IV. Bioorganic & medicinal chemistry letters 20070515
Beta-methyl substitution of cyclohexylalanine in Dmt-Tic-Cha-Phe peptides results in highly potent delta opioid antagonists. Journal of medicinal chemistry 20070125
Chemical and biological characterization of new Re(CO)3/[99mTc](CO)3 bombesin analogues. Nuclear medicine and biology 20070101
Therapy of established B16-F10 melanoma tumors by a single vaccination of CTL/T helper peptides in VacciMax. Journal of translational medicine 20070101
Tuning wasp toxin structure for nicotinic receptor antagonism: cyclohexylalanine-containing analogues as potent and voltage-dependent blockers. ChemMedChem 20060301
Comparative agonist/antagonist responses in mutant human C5a receptors define the ligand binding site. The Journal of biological chemistry 20050506
Ferrioxamine B analogues: targeting the FoxA uptake system in the pathogenic Yersinia enterocolitica. Journal of the American Chemical Society 20050202
Up-regulation of adenosine A1 receptor binding in pentylenetetrazol kindling in mice: effects of angiotensin IV. Brain research 20050125
Tuning stability of coiled-coil heterotrimers by selection of steric matching partners. Organic letters 20041111
Strand orientation by steric matching: a designed antiparallel coiled-coil trimer. Journal of the American Chemical Society 20041110
Investigation of the nature of the methionine-pi interaction in beta-hairpin peptide model systems. Protein science : a publication of the Protein Society 20040901
Comparison of C-H...pi and hydrophobic interactions in a beta-hairpin peptide: impact on stability and specificity. Journal of the American Chemical Society 20040225
Sample preparation and determination of gabapentin in venous and capillary blood using liquid chromatography-tandem mass spectrometry. Journal of pharmaceutical and biomedical analysis 20040204
Sequential and specific exchange of multiple coiled-coil components. Journal of the American Chemical Society 20031029
Modifications to the N-terminus but not the C-terminus of calcitonin gene-related peptide(8-37) produce antagonists with increased affinity. Journal of medicinal chemistry 20030605
Inhibition of human napsin A. Protein and peptide letters 20030201
Specific control of peptide assembly with combined hydrophilic and hydrophobic interfaces. Journal of the American Chemical Society 20030122
Peptide tic-tac-toe: heterotrimeric coiled-coil specificity from steric matching of multiple hydrophobic side chains. Journal of the American Chemical Society 20020821
Selective aromatic interactions in beta-hairpin peptides. Journal of the American Chemical Society 20020814
The methyl group of N(alpha)(Me)Arg-containing peptides disturbs the active-site geometry of thrombin, impairing efficient cleavage. Journal of molecular biology 20020301
Mapping the ligand-binding site on the C5a receptor: arginine74 of C5a contacts aspartate282 of the C5a receptor. Biochemistry 20011120
Coiled-coil formation governed by unnatural hydrophobic core side chains. Journal of the American Chemical Society 20011107
Physicochemical determinants of passive membrane permeability: role of solute hydrogen-bonding potential and volume. Journal of medicinal chemistry 20011025
Subsite specificity of trypanosomal cathepsin L-like cysteine proteases. Probing the S2 pocket with phenylalanine-derived amino acids. European journal of biochemistry 20010501
An activation switch in the ligand binding pocket of the C5a receptor. The Journal of biological chemistry 20010202
Properties