MOTILIN (HUMAN, PORCINE)
Title | Journal |
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The antibiotic azithromycin is a motilin receptor agonist in human stomach: comparison with erythromycin. | British journal of pharmacology 20130401 |
Can small non-peptide motilin agonists force a breakthrough as gastroprokinetic drugs? | British journal of pharmacology 20121001 |
Acute effects of different glycemic index diets on serum motilin, orexin and neuropeptide Y concentrations in healthy individuals. | Neuropeptides 20120601 |
Gastrointestinal hormone concentrations associated with gastric feeding in critically ill patients. | JPEN. Journal of parenteral and enteral nutrition 20120301 |
A new strategy for metabolic stabilization of motilin using the C-terminal part of ghrelin. | Peptides 20120201 |
Transcription factor binding site polymorphism in the motilin gene associated with left-sided displacement of the abomasum in German Holstein cattle. | PloS one 20120101 |
Influence of acute exposure to high altitude on basal and postprandial plasma levels of gastroenteropancreatic peptides. | PloS one 20120101 |
Myenteric neural network activated by motilin in the stomach of Suncus murinus (house musk shrew). | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20111201 |
[Long-term efficacy and safety research on functional dyspepsia treated with electroacupuncture and Zhizhu Kuanzhong capsule]. | Zhongguo zhen jiu = Chinese acupuncture & moxibustion 20111201 |
[Effects of transcutaneous electrical acupoint stimulation combined with general anesthesia on changes of gastric dynamics in controlled hypotension dogs]. | Zhen ci yan jiu = Acupuncture research 20111201 |
Motilin stimulates preadipocyte proliferation and differentiation and adipocyte lipid storage. | American journal of physiology. Endocrinology and metabolism 20111101 |
The paraventricular nucleus modulates thyroidal motilin release and rat gastric motility. | Journal of neuroendocrinology 20110901 |
Lactulose in fat-free milk, rather than increased ghrelin and motilin level, might help for solving constipation: author update. | Nutrition (Burbank, Los Angeles County, Calif.) 20110601 |
Simotang enhances gastrointestinal motility, motilin and cholecystokinin expression in chronically stressed mice. | World journal of gastroenterology 20110328 |
Effect of ginger on gastric motility and symptoms of functional dyspepsia. | World journal of gastroenterology 20110107 |
Effect of ω-3 fatty acid on gastrointestinal motility after abdominal operation in rats. | Mediators of inflammation 20110101 |
Comparison of the effects of pantethine and fursultiamine on plasma gastrointestinal peptide levels in healthy volunteers. | Biological & pharmaceutical bulletin 20110101 |
9-Dihydroerythromycin ethers as motilin agonists--developing structure-activity relationships for potency and safety. | Bioorganic & medicinal chemistry 20101101 |
Physiological characteristics of gastric contractions and circadian gastric motility in the free-moving conscious house musk shrew (Suncus murinus). | American journal of physiology. Regulatory, integrative and comparative physiology 20101001 |
Pharmacologic management of chronic constipation. | Gastroenterology clinics of North America 20100901 |
Endogenous gastric mediators: patho-physiological role and measurements. | Current protocols in toxicology 20100801 |
Mechanism of interdigestive migrating motor complex in conscious dogs. | Journal of gastroenterology 20100501 |
Effects of motilin on intracellular free calcium in cultured smooth muscle cells from the antrum of neonatal rats. | Acta physiologica (Oxford, England) 20100501 |
Colitis affects the smooth muscle and neural response to motilin in the rabbit antrum. | British journal of pharmacology 20100101 |
Structure-activity relationships of 9-substituted-9-dihydroerythromycin-based motilin agonists: optimizing for potency and safety. | Journal of medicinal chemistry 20091112 |
[Promotility drugs use in critical care: indications and limits?]. | Annales francaises d'anesthesie et de reanimation 20091101 |
Emerging drugs for chronic constipation. | Expert opinion on emerging drugs 20090901 |
An orally active motilin receptor antagonist, MA-2029, inhibits motilin-induced gastrointestinal motility, increase in fundic tone, and diarrhea in conscious dogs without affecting gastric emptying. | European journal of pharmacology 20090801 |
Berberine against gastrointestinal peptides elevation and mucous secretion in hyperthyroid diarrheic rats. | Regulatory peptides 20090605 |
GSK962040: a small molecule, selective motilin receptor agonist, effective as a stimulant of human and rabbit gastrointestinal motility. | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20090601 |
Prokinetic drugs for feed intolerance in critical illness: current and potential therapies. | Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine 20090601 |
[Clinical observation on transcutaneous electrical acupoint stimulation for treatment of functional dyspepsia]. | Zhongguo zhen jiu = Chinese acupuncture & moxibustion 20090601 |
Effect of TZP-201, a novel motilin receptor antagonist, in the colon of the musk shrew (Suncus murinus). | The Journal of pharmacy and pharmacology 20090301 |
Discovery of N-(3-fluorophenyl)-1-[(4-([(3S)-3-methyl-1-piperazinyl]methyl)phenyl)acetyl]-4-piperidinamine (GSK962040), the first small molecule motilin receptor agonist clinical candidate. | Journal of medicinal chemistry 20090226 |
An immunocytochemical study of the endocrine cells in the stomach and duodenum of Zonotrichia capensis subtorquata (Passeriformes, Emberizidae). | Acta histochemica 20090101 |
Current treatment of nausea and vomiting associated with gastroparesis: antiemetics, prokinetics, tricyclics. | Gastrointestinal endoscopy clinics of North America 20090101 |
Predictors of gastric myoelectrical activity in type 2 diabetes mellitus. | Journal of clinical gastroenterology 20090101 |
Renzapride: a new drug for the treatment of constipation in the irritable bowel syndrome. | Expert opinion on investigational drugs 20081101 |
A single-blinded, randomized pilot study evaluating effects of electroacupuncture in diabetic patients with symptoms suggestive of gastroparesis. | Journal of alternative and complementary medicine (New York, N.Y.) 20080901 |
Effect of ileal infusion of short-chain fatty acids on pancreatic prandial secretion and gastrointestinal hormones in pigs. | Pancreas 20080801 |
Effect of motilin on the discharge of rat hippocampal neurons responding to gastric distension and its potential mechanism. | Peptides 20080401 |
Oral administration of MA-2029, a novel selective and competitive motilin receptor antagonist, inhibits motilin-induced intestinal contractions and visceral pain in rabbits. | European journal of pharmacology 20080310 |
Mutational analysis of predicted intracellular loop domains of human motilin receptor. | American journal of physiology. Gastrointestinal and liver physiology 20080201 |
Identification of genes for the ghrelin and motilin receptors and a novel related gene in fish, and stimulation of intestinal motility in zebrafish (Danio rerio) by ghrelin and motilin. | General and comparative endocrinology 20080101 |
Effects of motilin and mitemcinal (GM-611) on gastrointestinal contractile activity in rhesus monkeys in vivo and in vitro. | Digestive diseases and sciences 20071101 |
Emerging drugs for postoperative ileus. | Expert opinion on emerging drugs 20071101 |
Effects and probable mechanisms of electroacupuncture at the Zusanli point on upper gastrointestinal motility in rabbits. | Journal of gastroenterology and hepatology 20071001 |
A comparison study between early enteral nutrition and parenteral nutrition in severe burn patients. | Burns : journal of the International Society for Burn Injuries 20070901 |
Distribution and electrophysiological effects of motilin in Purkinje cells. | Neuroreport 20070827 |
[Physiological effects of cold and cool Chinese herbal medicine of channel tropism of stomach on rats with stomach-heat syndrome]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070601 |
Effect of acupuncture at Foot-Yangming Meridian on gastric mucosal blood flow, gastric motility and brain-gut peptide. | World journal of gastroenterology 20070421 |
Mitemcinal (GM-611), an orally active motilin agonist, facilitates defecation in rabbits and dogs without causing loose stools. | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20070401 |
Differences between the abilities of tegaserod and motilin receptor agonists to stimulate gastric motility in vitro. | British journal of pharmacology 20070201 |
Mitemcinal (GM-611), an orally active motilin receptor agonist, accelerates colonic motility and bowel movement in conscious dogs. | Inflammopharmacology 20070201 |
Therapeutic strategies for the management of delayed gastric emptying after pancreatic resection. | Langenbeck's archives of surgery 20070101 |
Effects of mitemcinal (GM-611), an acid-resistant nonpeptide motilin receptor agonist, on the gastrointestinal contractile activity in conscious dogs. | Pharmacology 20070101 |
Nonsteroidal anti-inflammatory drugs induce hypermotilinemia and disturbance of interdigestive migrating contractions in instrumented dogs. | Journal of veterinary pharmacology and therapeutics 20061201 |
[Effects of acute hypobaric hypoxia on gastric emptying and intestinal propulsion: experiment with rats]. | Zhonghua yi xue za zhi 20060912 |
[Clinicopharmacological study of gastrointestinal drugs from the viewpoint of postmarketing development]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20060901 |
[Evidence for the presence of motilin receptor and a study on the mechanism of motilin induced Ca2+ signaling in rat myenteric neurons]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20060901 |
[Regulative effect of leptin on gastric motility: experiment with conscious rats]. | Zhonghua yi xue za zhi 20060829 |
Intragastric acidification inhibits motilin-induced phase III activity in humans. | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20060801 |
Preproghrelin Leu72Met polymorphism predicts a lower rate of developing renal dysfunction in type 2 diabetic nephropathy. | European journal of endocrinology 20060701 |
Circulating ghrelin levels after food intake during different phases of the migrating motor complex in man. | European journal of clinical investigation 20060701 |
[Effects of intra-amygdaloid injection of motilin on the interdigestive migrating myoelectrical complex in rat]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20060701 |
Differential contributions of motilin receptor extracellular domains for peptide and non-peptidyl agonist binding and activity. | The Journal of biological chemistry 20060505 |
Clinical application of an enzyme immunoassay for cholecystokinin-like immunoreactive substance for determination of the human plasma levels: the effect of metoclopramide on gastrointestinal peptides and stress-related hormones. | Journal of peptide science : an official publication of the European Peptide Society 20060501 |
[Effect of motilin on intracellular free calcium of antral smooth muscle cells and its mechanisms]. | Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20060501 |
Influence of motilin on gastric fundus tone and on meal-induced satiety in man: role of cholinergic pathways. | The American journal of gastroenterology 20060401 |
Preproghrelin Leu72Met polymorphism is not associated with type 2 diabetes mellitus. | Metabolism: clinical and experimental 20060301 |
Effects of pirenzepine on Dai-kenchu-to-induced elevation of the plasma neuropeptide levels in humans. | Biological & pharmaceutical bulletin 20060101 |
Effects of itopride hydrochloride on plasma gut-regulatory peptide and stress-related hormone levels in healthy human subjects. | Pharmacology 20060101 |
A motilin agonist, erythromycin, decreases circulating growth hormone levels in normal subjects but not in diabetic subjects. | Journal of diabetes and its complications 20060101 |
Ghrelin precursor gene polymorphism and methamphetamine dependence in the Korean population. | Neuroscience research 20051201 |
Prokineticin-2, motilin, ghrelin and metoclopramide: prokinetic utility in mouse stomach and colon. | European journal of pharmacology 20051107 |
Small intestinal manometry in patients with systemic sclerosis. | European journal of gastroenterology & hepatology 20051101 |
Preproghrelin Leu72Met polymorphism in obese Korean children. | Journal of pediatric endocrinology & metabolism : JPEM 20051101 |
Basic and clinical pharmacology of new motility promoting agents. | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20051001 |
[Effects of acupuncture on the gastric motivity in patients with functional dyspepsia]. | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20051001 |
Regulation of vascular reactivity by established and emerging GPCRs. | Trends in pharmacological sciences 20050901 |
Effects of domperidone on human plasma levels of motilin, somatostatin, gastrin, adrenocorticotropic hormone and cortisol. | Biological & pharmaceutical bulletin 20050901 |
[Distribution and role of motilin receptor in the amygdala of rats]. | Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20050901 |
Effect of erythromycin on gastric dysmotility and neuroendocrine peptides in rats with diabetes mellitus. | Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih 20050901 |
[Effects of intrahippocampal microinjection of motilin on interdigestive migrating myoelectrical complexes of rat duodenum]. | Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20050801 |
Demonstration of a specific site of covalent labeling of the human motilin receptor using a biologically active photolabile motilin analog. | The Journal of pharmacology and experimental therapeutics 20050601 |
Ecabet sodium raises plasma levels of calcitonin generelated peptide and substance P in healthy humans. | The Journal of pharmacy and pharmacology 20050601 |
[Measurements and significance of serum gastrin, plasma motilin and serum beta-endorphin in patients with severe burns]. | Zhonghua wai ke za zhi [Chinese journal of surgery] 20050601 |
Comparison of the gastroprokinetic effects of ghrelin, GHRP-6 and motilin in rats in vivo and in vitro. | European journal of pharmacology 20050516 |
Mutation analysis of the preproghrelin gene: no association with obesity and type 2 diabetes. | Clinical biochemistry 20050501 |
Excitatory actions of motilin on myenteric neurons of the guinea-pig small intestine. | Autonomic neuroscience : basic & clinical 20050331 |
Omeprazole raises somatostatin and motilin in human plasma. | Biological & pharmaceutical bulletin 20050201 |
Evidence for the presence of motilin, ghrelin, and the motilin and ghrelin receptor in neurons of the myenteric plexus. | Regulatory peptides 20050115 |
Signaling pathways mediating gastrointestinal smooth muscle contraction and MLC20 phosphorylation by motilin receptors. | American journal of physiology. Gastrointestinal and liver physiology 20050101 |
Delayed gastric emptying and intestinal hormones following pancreatoduodenectomy. | Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20050101 |
Effect of environmental hyperthermia on gastrin, somatostatin and motilin in rat ulcerated antral mucosa. | World journal of gastroenterology 20041201 |
Effects of motilin and ursodeoxycholic acid on gastrointestinal myoelectric activity of different origins in fasted rats. | World journal of gastroenterology 20040901 |
Effect of the motilin agonist KC 11458 on gastric emptying in diabetic gastroparesis. | Alimentary pharmacology & therapeutics 20040801 |
Relationship between intraduodenal 5-hydroxytryptamine release and interdigestive contractions in dogs. | Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20040601 |
Discovery of a potent and novel motilin agonist. | Journal of medicinal chemistry 20040325 |
Neuromodulation of experimental Shigella infection reduces damage to the gut mucosa. | Microbes and infection 20040301 |
Screening of a large panel of gastrointestinal peptide plasma levels is not adapted for the evaluation of digestive damage following irradiation. | Canadian journal of physiology and pharmacology 20040201 |
Autonomic neuropathy and gastrointestinal motility disorders in children and adolescents with type 1 diabetes mellitus. | Journal of pediatric gastroenterology and nutrition 20040101 |
Quantitative determination of the polypeptide motilin in rat plasma by externally calibrated liquid chromatography/electrospray ionization mass spectrometry. | Rapid communications in mass spectrometry : RCM 20040101 |
[Clinical observation on treatment of gastro-esophageal reflux with modified zhizhu pill]. | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20040101 |
Effect of motilin on endogenous release of insulin in conscious dogs in the fed state. | Digestive diseases and sciences 20031201 |
Excitatory effects of motilin in the hippocampus on gastric motility in rats. | Brain research 20030912 |
Gastrointestinal motility disorders and gastrointestinal prokinetic therapy. | The Veterinary clinics of North America. Small animal practice 20030901 |
[Effect of motilin on gastric smooth contraction induced by interstitial cells of Cajal]. | Zhonghua yi xue za zhi 20030825 |
Intestinal aspects of cholesterol gallstone formation. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20030701 |
Motilin-bicelle interactions: membrane position and translational diffusion. | FEBS letters 20030619 |
Differential effects of motilin on interdigestive motility of the human gastric antrum, pylorus, small intestine and gallbladder. | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20030401 |
[Synthetic studies of microbial natural products from microorganisms]. | The Japanese journal of antibiotics 20030201 |
The effects of duodenal peptides on glucagon-like peptide-1 secretion from the ileum. A duodeno--ileal loop? | Regulatory peptides 20021231 |
Motilin regulates interdigestive gastric blood flow in dogs. | Gastroenterology 20021101 |
(13)C-(1)H NMR relaxation and fluorescence anisotropy decay study of tyrosine dynamics in motilin. | Biophysical journal 20021101 |
Atropine-induced gastric dysrhythmia is not normalized by electroacupuncture. | Digestive diseases and sciences 20021101 |
The structure of erythromycin enol ether as a model for its activity as a motilide. | Journal of medicinal chemistry 20021024 |
Intraduodenal capsaicin inhibits gastric migrating motor complex via an extrinsic neural reflex in conscious dogs. | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20021001 |
A variation in the ghrelin gene increases weight and decreases insulin secretion in tall, obese children. | The Journal of clinical endocrinology and metabolism 20020801 |
[Effect of jianpi wenshen decoction on serum gastrin, plasma motilin and somatostatin in patients of diabetic diarrhea]. | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20020801 |
[The other gastrointestinal hormones in diabetes mellitus]. | Nihon rinsho. Japanese journal of clinical medicine 20020701 |
Effect of high temperature on gastrin, somatostatin and motilin production in ulcerous gastric antral mucosa of rats. | Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20020701 |
Design and synthesis of novel tetra-peptide motilin agonists. | Bioorganic & medicinal chemistry 20020601 |
In vitro evaluation of motilin agonism by macrolide immunosuppressive drugs. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20020601 |
The motilin pharmacophore in CHO cells expressing the human motilin receptor. | Biochemical and biophysical research communications 20020517 |
Effects of motilin on human interdigestive gastrointestinal and gallbladder motility, and involvement of 5HT3 receptors. | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20020401 |
Differential determinants for peptide and non-peptidyl ligand binding to the motilin receptor. Critical role of second extracellular loop for peptide binding and action. | The Journal of biological chemistry 20020322 |
Potentiation of motilin-induced contraction by nitric oxide synthase inhibition in the isolated chicken gastrointestinal tract. | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20020201 |
Design and synthesis of motilin antagonists derived from the [1-4] fragment of porcine motilin. | Journal of medicinal chemistry 20020131 |
Effect of erythromycin on gastroduodenal contractile activity in developing neonates. | Journal of pediatric gastroenterology and nutrition 20020101 |
Effects of adjustable gastric banding on altered gut neuropeptide levels in morbidly obese patients. | Obesity surgery 20011201 |
Pressure-geometry relationship in the antroduodenal region in humans. | American journal of physiology. Gastrointestinal and liver physiology 20011101 |
Identification of peptide ligand-binding domains within the human motilin receptor using photoaffinity labeling. | The Journal of biological chemistry 20010921 |
Effects of a motilin receptor agonist (ABT-229) on upper gastrointestinal symptoms in type 1 diabetes mellitus: a randomised, double blind, placebo controlled trial. | Gut 20010901 |
Effects of mosapride citrate on human plasma levels of motilin, gastrin, somatostatin, and secretin. | Biological & pharmaceutical bulletin 20010901 |
Gastric myoelectrical activity and gut hormone secretion in myotonic dystrophy. | European journal of gastroenterology & hepatology 20010701 |
The in vitro pharmacological profile of prucalopride, a novel enterokinetic compound. | European journal of pharmacology 20010629 |
Intraduodenal and intrajejunal administration of the herbal medicine, dai-kenchu-tou, stimulates small intestinal motility via cholinergic receptors in conscious dogs. | Digestive diseases and sciences 20010601 |
Interdigestive gallbladder emptying, antroduodenal motility, and motilin release patterns are altered in cholesterol gallstone patients. | Digestive diseases and sciences 20010601 |
Demonstration of a functional motilin receptor in TE671 cells from human cerebellum. | Brain research 20010323 |
Effect of duodenectomy on gastric motility and gastric hormones in dogs. | Annals of surgery 20010301 |
Contractile effects and intracellular Ca2+ signalling induced by motilin and erythromycin in the circular smooth muscle of human colon. | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20010201 |
Immunohistochemical study of the distribution of endocrine cells in the gastrointestinal tract of the camel (Camelus bactrianus). | European journal of morphology 20010201 |
Growth hormone secretagogue receptor family members and ligands. | Endocrine 20010201 |
Design and synthesis of N-terminal cyclic motilin partial peptides: a novel pure motilin antagonist. | Chemical & pharmaceutical bulletin 20010101 |
Effects of intraduodenal bile on interdigestive gastrointestinal and gallbladder motility in healthy subjects. | Digestion 20010101 |
Discovery of the first non-peptide antagonist of the motilin receptor. | Drug design and discovery 20010101 |
Gastroprokinetic effect and mechanism of SK-896, a new motilin analogue, during the interdigestive period in conscious dogs. | Pharmacology 20010101 |
Effect of electrical stimulation on acupuncture points in diabetic patients with gastric dysrhythmia: a pilot study. | Digestion 20010101 |
Motilin and motilin receptors: characterization and functional significance. | Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie 20010101 |
An unusual metastatic motilin-secreting neuroendocrine tumour with a 20-year survival. Pathological, biochemical and motility features. | Digestion 20010101 |
Receptor for motilin identified in the human gastrointestinal system. | Science (New York, N.Y.) 19990625 |
Erythromycin derivatives ABT 229 and GM 611 act on motilin receptors in the rabbit duodenum. | Clinical and experimental pharmacology & physiology 19990301 |
GM-109: a novel, selective motilin receptor antagonist in the smooth muscle of the rabbit small intestine. | The Journal of pharmacology and experimental therapeutics 19950501 |
Effect of pinaverium and other calcium channel blockers on contraction of isolated gastric antral smooth muscle cells caused by gastrointestinal hormones. | Life sciences 19940101 |