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R(+)-iaa-94

CAS No.:
54197-31-8
Catalog Number:
AG00D7ZB
Molecular Formula:
C17H18Cl2O4
Molecular Weight:
357.2284
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1mg
≥95%
1 week
United States
$97
- +
5mg
≥95%
1 week
United States
$147
- +
10mg
99%
1 week
United States
$210
- +
25mg
≥95%
1 week
United States
$410
- +
50mg
99%
1 week
United States
$571
- +
Product Description
Catalog Number:
AG00D7ZB
Chemical Name:
R(+)-iaa-94
CAS Number:
54197-31-8
Molecular Formula:
C17H18Cl2O4
Molecular Weight:
357.2284
MDL Number:
MFCD28133534
IUPAC Name:
2-[[(2S)-6,7-dichloro-2-cyclopentyl-2-methyl-1-oxo-3H-inden-5-yl]oxy]acetic acid
InChI:
InChI=1S/C17H18Cl2O4/c1-17(10-4-2-3-5-10)7-9-6-11(23-8-12(20)21)14(18)15(19)13(9)16(17)22/h6,10H,2-5,7-8H2,1H3,(H,20,21)/t17-/m0/s1
InChI Key:
RNOJGTHBMJBOSP-KRWDZBQOSA-N
SMILES:
OC(=O)COc1cc2C[C@](C(=O)c2c(c1Cl)Cl)(C)C1CCCC1
Properties
Complexity:
491  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0
Exact Mass:
356.058g/mol
Formal Charge:
0
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
357.227g/mol
Monoisotopic Mass:
356.058g/mol
Rotatable Bond Count:
4  
Topological Polar Surface Area:
63.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
5.1  
Literature
Title Journal
Regulation of colon cancer cell migration and invasion by CLIC1-mediated RVD. Molecular and cellular biochemistry 20120601
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. Bioorganic & medicinal chemistry letters 20101101
Direct evidence of chloride ion efflux in ischaemic and pharmacological preconditioning of cultured cardiomyocytes. Cardiovascular research 20100801
Chloride channel blockers inhibit iNOS expression and NO production in IFNgamma-stimulated microglial BV2 cells. Brain research 20090724
Toxicity and disruption of midgut physiology in larvae of the European corn borer, Ostrinia nubilalis, by anion transporter blockers. Archives of insect biochemistry and physiology 20090301
CLIC1 function is required for beta-amyloid-induced generation of reactive oxygen species by microglia. The Journal of neuroscience : the official journal of the Society for Neuroscience 20081105
Vasomotion has chloride-dependency in rat mesenteric small arteries. Pflugers Archiv : European journal of physiology 20081101
Functional characteristics and molecular identification of swelling-activated chloride conductance in adult rabbit heart ventricles. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20080201
The volume-sensitive chloride channel inhibitors prevent both contractile dysfunction and apoptosis induced by doxorubicin through PI3kinase, Akt and Erk 1/2. European journal of heart failure 20080101
Intracellular signalling pathways in the vasoconstrictor response of mouse afferent arterioles to adenosine. Acta physiologica (Oxford, England) 20071001
Roles of volume-sensitive chloride channel in excitotoxic neuronal injury. The Journal of neuroscience : the official journal of the Society for Neuroscience 20070207
[Role of calcium-activated chloride channels in the regulation of pulmonary vascular tone in rats]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20060501
Relationship of intracellular free Ca2+ concentration and calcium-activated chloride channels of pulmonary artery smooth muscle cells in rats under hypoxic conditions. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20060101
Cl- channels are expressed in human normal monocytes: a functional role in migration, adhesion and volume change. Clinical and experimental immunology 20041201
Chloride efflux is involved in ET-1 and 5-HT-induced contraction in rabbit basilar artery. Journal of cardiovascular pharmacology 20041101
Effects of chloride channel blockers on rat renal vascular responses to angiotensin II and norepinephrine. American journal of physiology. Renal physiology 20040201
Role of Cl- currents in rat aortic smooth muscle activation by prostaglandin F2 alpha. European journal of pharmacology 20031128
Inhibitors of swelling-activated chloride channels increase infarct size and apoptosis in rabbit myocardium. Fundamental & clinical pharmacology 20031001
Regulatory volume decrease in human esophageal epithelial cells. American journal of physiology. Gastrointestinal and liver physiology 20021001
Pharmacological preconditioning in rabbit myocardium is blocked by chloride channel inhibition. Cardiovascular research 20020815
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. The Journal of biological chemistry 20020419
Loading of nitrate into the xylem: apoplastic nitrate controls the voltage dependence of X-QUAC, the main anion conductance in xylem-parenchyma cells of barley roots. The Plant journal : for cell and molecular biology 20020401
Sensitivity of the plant vacuolar malate channel to pH, Ca2+ and anion-channel blockers. The Journal of membrane biology 20020301
Role of Cl- current in endothelin-1-induced contraction in rabbit basilar artery. American journal of physiology. Heart and circulatory physiology 20011101
Chloride channel inhibition does block the protection of ischemic preconditioning in myocardium. Journal of molecular and cellular cardiology 20011001
[(Dihydroindenyl)oxy]alkonic acid inhibits the cystic fibrosis transmembrane conductance regulator. European journal of pharmacology 20010831
Measurement of chloride flux associated with the myogenic response in rat cerebral arteries. The Journal of physiology 20010801
Role of chloride in constriction of descending vasa recta by angiotensin II. American journal of physiology. Regulatory, integrative and comparative physiology 20010601
Properties