TOFA
| Title | Journal |
|---|---|
| The relationship of thioredoxin-1 and cisplatin resistance: its impact on ROS and oxidative metabolism in lung cancer cells. | Molecular cancer therapeutics 20120301 |
| Inhibition of p53 expression modifies the specificity of chromatin binding by the androgen receptor. | Oncotarget 20120201 |
| Metabolic regulation of invadopodia and invasion by acetyl-CoA carboxylase 1 and de novo lipogenesis. | PloS one 20120101 |
| SCD1 inhibition causes cancer cell death by depleting mono-unsaturated fatty acids. | PloS one 20120101 |
| Supplementation of pyruvate prevents palmitate-induced impairment of glucose uptake in C2 myotubes. | Molecular and cellular endocrinology 20111015 |
| The lipogenesis pathway as a cancer target. | Journal of medicinal chemistry 20110825 |
| TOFA (5-tetradecyl-oxy-2-furoic acid) reduces fatty acid synthesis, inhibits expression of AR, neuropilin-1 and Mcl-1 and kills prostate cancer cells independent of p53 status. | Cancer biology & therapy 20110701 |
| Divergent effects of human cytomegalovirus and herpes simplex virus-1 on cellular metabolism. | PLoS pathogens 20110701 |
| Hypothalamic Angptl4/Fiaf is a novel regulator of food intake and body weight. | Diabetes 20101101 |
| Ethanol enhances hepatitis C virus replication through lipid metabolism and elevated NADH/NAD+. | The Journal of biological chemistry 20100108 |
| Acetyl-CoA carboxylase-alpha inhibitor TOFA induces human cancer cell apoptosis. | Biochemical and biophysical research communications 20090731 |
| De novo fatty-acid synthesis and related pathways as molecular targets for cancer therapy. | British journal of cancer 20090505 |
| Legionella pneumophila couples fatty acid flux to microbial differentiation and virulence. | Molecular microbiology 20090301 |
| Effect of centrally administered C75, a fatty acid synthase inhibitor, on gastric emptying and gastrointestinal transit in mice. | European journal of pharmacology 20081024 |
| Chronic suppression of acetyl-CoA carboxylase 1 in beta-cells impairs insulin secretion via inhibition of glucose rather than lipid metabolism. | The Journal of biological chemistry 20080523 |
| 1-11C-acetate as a PET radiopharmaceutical for imaging fatty acid synthase expression in prostate cancer. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20080201 |
| Expression, purification, and characterization of human acetyl-CoA carboxylase 2. | Protein expression and purification 20070501 |
| Fatty acid synthase inhibition activates AMP-activated protein kinase in SKOV3 human ovarian cancer cells. | Cancer research 20070401 |
| Fatty acid synthase: a novel target for antiglioma therapy. | British journal of cancer 20061009 |
| Sterol regulatory element-binding protein 1 mediates liver X receptor-beta-induced increases in insulin secretion and insulin messenger ribonucleic acid levels. | Endocrinology 20060801 |
| Nutritional status influences socially regulated foraging ontogeny in honey bees. | The Journal of experimental biology 20051201 |
| Cross-talk between an activator of nuclear receptors-mediated transcription and the D1 dopamine receptor signaling pathway. | Pharmacology, biochemistry, and behavior 20050301 |
| Fatty acid synthase inhibition triggers apoptosis during S phase in human cancer cells. | Cancer research 20031101 |
| Leptin receptor-deficient obese Zucker rats reduce their food intake in response to a systemic supply of calories from glucose. | Diabetes 20030201 |
| Fatty acid synthase inhibition in human breast cancer cells leads to malonyl-CoA-induced inhibition of fatty acid oxidation and cytotoxicity. | Biochemical and biophysical research communications 20010713 |