Bay 60-7550
| Title | Journal |
|---|---|
| Cyclic GMP-mediated memory enhancement in the object recognition test by inhibitors of phosphodiesterase-2 in mice. | Psychopharmacology 20160201 |
| Inhibition of phosphodiesterase 2 augments cGMP and cAMP signaling to ameliorate pulmonary hypertension. | Circulation 20140805 |
| Phosphodiesterase 2A localized in the spinal cord contributes to inflammatory pain processing. | Anesthesiology 20140801 |
| X-ray crystal structure of phosphodiesterase 2 in complex with a highly selective, nanomolar inhibitor reveals a binding-induced pocket important for selectivity. | Journal of the American Chemical Society 20130814 |
| Phosphodiesterase-2 inhibitor reverses corticosterone-induced neurotoxicity and related behavioural changes via cGMP/PKG dependent pathway. | The international journal of neuropsychopharmacology 20130501 |
| Phosphodiesterase 2 inhibitors promote axonal outgrowth in organotypic slice co-cultures. | Neuro-Signals 20130101 |
| Inhibition of phoshodiesterase type 2 or type 10 reverses object memory deficits induced by scopolamine or MK-801. | Behavioural brain research 20130101 |
| Pendrin protein abundance in the kidney is regulated by nitric oxide and cAMP. | American journal of physiology. Renal physiology 20120915 |
| Mechanisms of carbon monoxide attenuation of tubuloglomerular feedback. | Hypertension (Dallas, Tex. : 1979) 20120601 |
| PDE5A suppression of acute beta-adrenergic activation requires modulation of myocyte beta-3 signaling coupled to PKG-mediated troponin I phosphorylation. | Basic research in cardiology 20100501 |
| Anxiolytic effects of phosphodiesterase-2 inhibitors associated with increased cGMP signaling. | The Journal of pharmacology and experimental therapeutics 20091101 |
| A novel PDE2A reporter cell line: characterization of the cellular activity of PDE inhibitors. | Molecular pharmaceutics 20090101 |
| Phosphodiesterase 2 and 5 inhibition attenuates the object memory deficit induced by acute tryptophan depletion. | European journal of pharmacology 20081214 |
| ANP-mediated cGMP signaling and phosphodiesterase inhibition in the rat cervical spinal cord. | Journal of chemical neuroanatomy 20060601 |
| Inhibition of phosphodiesterase 2 increases neuronal cGMP, synaptic plasticity and memory performance. | Neuropharmacology 20041201 |