Home Other Building Blocks 8-HYDROXYGUANINE

8-HYDROXYGUANINE

CAS No.:
5614-64-2
Catalog Number:
AG00D7YF
Molecular Formula:
C5H5N5O2
Molecular Weight:
167.1255
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Product Description
Catalog Number:
AG00D7YF
Chemical Name:
8-HYDROXYGUANINE
CAS Number:
5614-64-2
Molecular Formula:
C5H5N5O2
Molecular Weight:
167.1255
MDL Number:
MFCD00039991
IUPAC Name:
2-amino-7,9-dihydro-1H-purine-6,8-dione
InChI:
InChI=1S/C5H5N5O2/c6-4-8-2-1(3(11)10-4)7-5(12)9-2/h(H5,6,7,8,9,10,11,12)
InChI Key:
CLGFIVUFZRGQRP-UHFFFAOYSA-N
SMILES:
NC1NC(=O)C2=NC(=NC2=N1)O
EC Number:
227-035-6
NSC Number:
22720
Properties
Complexity:
342  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
167.044g/mol
Formal Charge:
0
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
4  
Isotope Atom Count:
0
Molecular Weight:
167.128g/mol
Monoisotopic Mass:
167.044g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
109A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-2.2  
Literature
Title Journal
Experimental evidence of oxidative stress in patients with l-2-hydroxyglutaric aciduria and that l-carnitine attenuates in vitro DNA damage caused by d-2-hydroxyglutaric and l-2-hydroxyglutaric acids. Toxicology in vitro : an international journal published in association with BIBRA 20170801
Action-at-a-distance mutagenesis induced by oxidized guanine in Werner syndrome protein-reduced human cells. Chemical research in toxicology 20150420
A functional Ser326Cys polymorphism in hOGG1 is associated with noise-induced hearing loss in a Chinese population. PloS one 20140101
Silver nanoparticles induce premutagenic DNA oxidation that can be prevented by phytochemicals from Gentiana asclepiadea. Mutagenesis 20121101
DNA sequence context effects on the glycosylase activity of human 8-oxoguanine DNA glycosylase. The Journal of biological chemistry 20121026
Radiation-induced formation of 2',3'-dideoxyribonucleosides in DNA: a potential signature of low-energy electrons. Journal of the American Chemical Society 20121024
Lead(II)-catalyzed oxidation of guanine in solution studied with electrospray ionization mass spectrometry. The journal of physical chemistry. B 20121004
Profiling cytosine oxidation in DNA by LC-MS/MS. Chemical research in toxicology 20120917
Probing charge transport in oxidatively damaged DNA sequences under the influence of structural fluctuations. The journal of physical chemistry. B 20120913
Thermodynamic consequences of the hyperoxidized guanine lesion guanidinohydantoin in duplex DNA. Chemical research in toxicology 20120820
Mutagenic bypass of 8-oxo-7,8-dihydroguanine (8-hydroxyguanine) by DNA polymerase κ in human cells. Chemical research in toxicology 20120820
Integrated molecular analysis indicates undetectable change in DNA damage in mice after continuous irradiation at ~ 400-fold natural background radiation. Environmental health perspectives 20120801
Enforced presentation of an extrahelical guanine to the lesion recognition pocket of human 8-oxoguanine glycosylase, hOGG1. The Journal of biological chemistry 20120720
The DNA glycosylases OGG1 and NEIL3 influence differentiation potential, proliferation, and senescence-associated signs in neural stem cells. Biochemical and biophysical research communications 20120713
Unzipping kinetics of duplex DNA containing oxidized lesions in an α-hemolysin nanopore. Journal of the American Chemical Society 20120704
Dental methacrylates may exert genotoxic effects via the oxidative induction of DNA double strand breaks and the inhibition of their repair. Molecular biology reports 20120701
DNA damage induced by micro- and nanoparticles--interaction with FPG influences the detection of DNA oxidation in the comet assay. Mutagenesis 20120701
Formation of ring-opened and rearranged products of guanine: mechanisms and biological significance. Free radical biology & medicine 20120701
Activation of ras signaling pathway by 8-oxoguanine DNA glycosylase bound to its excision product, 8-oxoguanine. The Journal of biological chemistry 20120615
Distinct pattern of oxidative DNA damage and DNA repair in follicular thyroid tumours. Journal of molecular endocrinology 20120601
DNA polymerase beta from Trypanosoma cruzi is involved in kinetoplast DNA replication and repair of oxidative lesions. Molecular and biochemical parasitology 20120601
A DNA oligomer containing 2,2,4-triamino-5(2H)-oxazolone is incised by human NEIL1 and NTH1. Mutation research 20120601
Overexpression of AtOGG1, a DNA glycosylase/AP lyase, enhances seed longevity and abiotic stress tolerance in Arabidopsis. Journal of experimental botany 20120601
Greater nucleic acids oxidation in the temporal lobe than the frontal lobe in SAMP8. Neuroreport 20120530
Iron and genome stability: an update. Mutation research 20120501
Human 8-oxoguanine-DNA glycosylase-1 is downregulated in human basal cell carcinoma. Molecular genetics and metabolism 20120501
Recognition of damaged DNA: structure and dynamic markers. Medicinal research reviews 20120501
Oxidation of the guanine nucleotide pool underlies cell death by bactericidal antibiotics. Science (New York, N.Y.) 20120420
DNA lesion alters global conformational dynamics of Y-family DNA polymerase during catalysis. The Journal of biological chemistry 20120413
Lowered nudix type 5 (NUDT5) expression leads to cell cycle retardation in HeLa cells. Molecular and cellular biochemistry 20120401
The mutagenic potential of 8-oxoG/single strand break-containing clusters depends on their relative positions. Mutation research 20120401
Biologically relevant oxidants and terminology, classification and nomenclature of oxidatively generated damage to nucleobases and 2-deoxyribose in nucleic acids. Free radical research 20120401
Age-dependent decline of DNA base excision repair activity in rat cortical neurons. Mechanisms of ageing and development 20120401
Urinary 8-oxoguanine as a predictor of survival in patients undergoing radiotherapy. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20120401
Regulation of oxidative DNA damage repair: the adenine:8-oxo-guanine problem. Cell cycle (Georgetown, Tex.) 20120315
Photosensitization of DNA by β-carbolines: kinetic analysis and photoproduct characterization. Organic & biomolecular chemistry 20120307
8-Oxoguanine DNA glycosylase 1 (OGG1) from the copepod Tigriopus japonicus: molecular characterization and its expression in response to UV-B and heavy metals. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20120301
Catalytic contributions of key residues in the adenine glycosylase MutY revealed by pH-dependent kinetics and cellular repair assays. Chemistry & biology 20120224
Direct analysis of 5-methylcytosine and 5-methyl-2'-deoxycytidine in human urine by isotope dilution LC-MS/MS: correlations with N-methylated purines and oxidized DNA lesions. Chemical research in toxicology 20120220
Replication bypass of the trans-4-Hydroxynonenal-derived (6S,8R,11S)-1,N(2)-deoxyguanosine DNA adduct by the sulfolobus solfataricus DNA polymerase IV. Chemical research in toxicology 20120220
Biochemical identification of a hydroperoxide derivative of the free 8-oxo-7,8-dihydroguanine base. Free radical biology & medicine 20120215
Urinary excretion of 8-oxo-7,8-dihydroguanine as biomarker of oxidative damage to DNA. Archives of biochemistry and biophysics 20120215
Copper oxide nanoparticle mediated DNA damage in terrestrial plant models. Environmental science & technology 20120207
2-hydroxylethyl methacrylate (HEMA), a tooth restoration component, exerts its genotoxic effects in human gingival fibroblasts trough methacrylic acid, an immediate product of its degradation. Molecular biology reports 20120201
DNA glycosylases: in DNA repair and beyond. Chromosoma 20120201
Reduced expression of DNA repair genes (XRCC1, XPD, and OGG1) in squamous cell carcinoma of head and neck in North India. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20120201
Global analysis of RNA oxidation in Saccharomyces cerevisiae. BioTechniques 20120201
Interaction between the Cockayne syndrome B and p53 proteins: implications for aging. Aging 20120201
Surprising repair activities of nonpolar analogs of 8-oxoG expose features of recognition and catalysis by base excision repair glycosylases. Journal of the American Chemical Society 20120125
Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling. The Biochemical journal 20120115
A DNA aptamer sensor for 8-oxo-7,8-dihydroguanine. Bioorganic & medicinal chemistry letters 20120115
Trinucleotide repeat DNA alters structure to minimize the thermodynamic impact of 8-oxo-7,8-dihydroguanine. Biochemistry 20120110
Oxidative stress, mitochondrial dysfunction, and aging. Journal of signal transduction 20120101
The specificity of UVA-induced DNA damage in human melanocytes. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20120101
8-oxoguanine in a quadruplex of the human telomere DNA sequence. The FEBS journal 20120101
Influence of the OGG1 Ser326Cys polymorphism on oxidatively damaged DNA and repair activity. Free radical biology & medicine 20120101
Association between 8-oxo-7,8-dihydroguanine excretion and risk of lung cancer in a prospective study. Free radical biology & medicine 20120101
A new proofreading mechanism for lesion bypass by DNA polymerase-λ. EMBO reports 20120101
Mitochondria-ros crosstalk in the control of cell death and aging. Journal of signal transduction 20120101
Polychlorinated biphenyls-induced oxidative stress on rat hippocampus: a neuroprotective role of quercetin. TheScientificWorldJournal 20120101
Contribution of HOGG1 Ser³²⁶Cys polymorphism to the development of prostate cancer in smokers: meta-analysis of 2779 cases and 3484 controls. PloS one 20120101
Protein kinases and transcription factors activation in response to UV-radiation of skin: implications for carcinogenesis. International journal of molecular sciences 20120101
Effect of daily consumption of probiotic yogurt on oxidative stress in pregnant women: a randomized controlled clinical trial. Annals of nutrition & metabolism 20120101
Association of mitochondrial DNA variations with lung cancer risk in a Han Chinese population from southwestern China. PloS one 20120101
Instability of (CTG)n•(CAG)n trinucleotide repeats and DNA synthesis. Cell & bioscience 20120101
Polymorphisms in base-excision & nucleotide-excision repair genes & prostate cancer risk in north Indian population. The Indian journal of medical research 20120101
DNA repair in human pluripotent stem cells is distinct from that in non-pluripotent human cells. PloS one 20120101
Controlled human wood smoke exposure: oxidative stress, inflammation and microvascular function. Particle and fibre toxicology 20120101
Overexpression of DNA polymerase zeta reduces the mitochondrial mutability caused by pathological mutations in DNA polymerase gamma in yeast. PloS one 20120101
Aberrant expression of N-methylpurine-DNA glycosylase influences patient survival in malignant gliomas. Journal of biomedicine & biotechnology 20120101
Free radicals and extrinsic skin aging. Dermatology research and practice 20120101
The Escherichia coli SOS gene dinF protects against oxidative stress and bile salts. PloS one 20120101
The association between OGG1 Ser326Cys polymorphism and lung cancer susceptibility: a meta-analysis of 27 studies. PloS one 20120101
Molecular mechanisms for age-associated mitochondrial deficiency in skeletal muscle. Journal of aging research 20120101
Adult neurogenesis transiently generates oxidative stress. PloS one 20120101
Impact of treadmill running and sex on hippocampal neurogenesis in the mouse model of amyotrophic lateral sclerosis. PloS one 20120101
[Generation of reactive oxygen species in water under exposure of visible or infrared irradiation at absorption band of molecular oxygen]. Biofizika 20120101
Genetic aspects of gastric cancer instability. TheScientificWorldJournal 20120101
Cigarette smoking accelerated brain aging and induced pre-Alzheimer-like neuropathology in rats. PloS one 20120101
Modulation of Neuronal Survival Factor MEF2 by Kinases in Parkinson's Disease. Frontiers in physiology 20120101
Modulation of oxidative DNA damage by repair enzymes XRCC1 and hOGG1. Journal of toxicology and environmental health. Part A 20120101
Eckol inhibits ultraviolet B-induced cell damage in human keratinocytes via a decrease in oxidative stress. Biological & pharmaceutical bulletin 20120101
Mitochondrial- and endoplasmic reticulum-associated oxidative stress in Alzheimer's disease: from pathogenesis to biomarkers. International journal of cell biology 20120101
Association of base excision repair gene polymorphisms with ESRD risk in a Chinese population. Oxidative medicine and cellular longevity 20120101
8-oxoguanine DNA glycosylases: one lesion, three subfamilies. International journal of molecular sciences 20120101
Association between environmental exposure to benzene and oxidative damage to nucleic acids in children. La Medicina del lavoro 20120101
Role of OGG1 Ser326Cys polymorphism and 8-oxoguanine DNA damage in risk assessment of squamous cell carcinoma of head and neck in North Indian population. Mutation research 20111224
Induction of DNA damage in human urothelial cells by the brominated flame retardant 2,2-bis(bromomethyl)-1,3-propanediol: role of oxidative stress. Toxicology 20111218
Combined exercise and insulin-like growth factor-1 supplementation induces neurogenesis in old rats, but do not attenuate age-associated DNA damage. Rejuvenation research 20111201
Effects of DPP-4 inhibition on cardiac metabolism and function in mice. Journal of molecular and cellular cardiology 20111201
Increased expression of versican in the inflammatory response to UVB- and reactive oxygen species-induced skin tumorigenesis. The American journal of pathology 20111201
Concordance between Results of Medium-term Liver Carcinogenesis Bioassays and Long-term Findings for Carcinogenic 2-Nitropropane and Non-carcinogenic1-Nitropropane in F344 Rats. Journal of toxicologic pathology 20111201
Silver nanoparticles down-regulate Nrf2-mediated 8-oxoguanine DNA glycosylase 1 through inactivation of extracellular regulated kinase and protein kinase B in human Chang liver cells. Toxicology letters 20111130
Spectral characterization of guanine C4-OH adduct: a radiation and quantum chemical study. The journal of physical chemistry. B 20111124
Evidence for upregulated repair of oxidatively induced DNA damage in human colorectal cancer. DNA repair 20111110
8-Hydroxyguanine: a base for discovery. DNA repair 20111110
Bisphenol A-glycidyl methacrylate induces a broad spectrum of DNA damage in human lymphocytes. Archives of toxicology 20111101
Nickel exposure induces oxidative damage to mitochondrial DNA in Neuro2a cells: the neuroprotective roles of melatonin. Journal of pineal research 20111101
Reduced expression of MUTYH with suppressive activity against mutations caused by 8-hydroxyguanine is a novel predictor of a poor prognosis in human gastric cancer. The Journal of pathology 20111101
Cardiac overexpression of 8-oxoguanine DNA glycosylase 1 protects mitochondrial DNA and reduces cardiac fibrosis following transaortic constriction. American journal of physiology. Heart and circulatory physiology 20111101
Oxidative stress in women with perimenopausal symptoms. Menopause (New York, N.Y.) 20111101
Utilizing G-quadruplex formation to target 8-oxoguanine in telomeric sequences. Bioorganic & medicinal chemistry letters 20111101
Siderite (FeCO₃) and magnetite (Fe₃O₄) overload-dependent pulmonary toxicity is determined by the poorly soluble particle not the iron content. Inhalation toxicology 20111101
[Mechanistic insight into hydrolysis of oxidized nucleotide diphosphates by human NUDT5]. Fukuoka igaku zasshi = Hukuoka acta medica 20111101
Chromium in drinking water: sources, metabolism, and cancer risks. Chemical research in toxicology 20111017
Hidden in plain sight: subtle effects of the 8-oxoguanine lesion on the structure, dynamics, and thermodynamics of a 15-base pair oligodeoxynucleotide duplex. Biochemistry 20111004
DNA replication and repair bypass machines. Current opinion in chemical biology 20111001
Nitrative and oxidative DNA damage caused by K-ras mutation in mice. Biochemical and biophysical research communications 20110923
Energetic preference of 8-oxoG eversion pathways in a DNA glycosylase. Journal of the American Chemical Society 20110921
Sequence-specific single-molecule analysis of 8-oxo-7,8-dihydroguanine lesions in DNA based on unzipping kinetics of complementary probes in ion channel recordings. Journal of the American Chemical Society 20110921
A prebiotic role for 8-oxoguanosine as a flavin mimic in pyrimidine dimer photorepair. Journal of the American Chemical Society 20110921
New insights on the barrel medic MtOGG1 and MtFPG functions in relation to oxidative stress response in planta and during seed imbibition. Plant physiology and biochemistry : PPB 20110901
Mutagenicity of secondary oxidation products of 8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate (8-hydroxy-2'- deoxyguanosine 5'-triphosphate). Mutation research 20110901
Effect of sodium and acetate ions on 8-hydroxyguanine formation in irradiated aqueous solutions of DNA and 2'-deoxyguanosine 5'-monophosphate. International journal of radiation biology 20110901
Genetic and epigenetic alterations of lysophosphatidic Acid receptor genes in rodent tumors by experimental models. Journal of toxicologic pathology 20110901
First Steps Towards an Understanding of a Mode ofCarcinogenic Action for Vanadium Pentoxide. Journal of toxicologic pathology 20110901
Turn-on DNA damage sensors for the direct detection of 8-oxoguanine and photoproducts in native DNA. Journal of the American Chemical Society 20110817
Incidence and persistence of 8-oxo-7,8-dihydroguanine within a hairpin intermediate exacerbates a toxic oxidation cycle associated with trinucleotide repeat expansion. DNA repair 20110815
Oxidative damage to RNA and expression patterns of MTH1 in the hippocampi of senescence-accelerated SAMP8 mice and Alzheimer's disease patients. Neurochemical research 20110801
Oxidatively modified nucleic acids in preclinical Alzheimer's disease (PCAD) brain. Mechanisms of ageing and development 20110801
Age-associated neurodegeneration and oxidative damage to lipids, proteins and DNA. Molecular aspects of medicine 20110801
Computational study of the deamination of 8-oxoguanine. The journal of physical chemistry. B 20110728
Generation of guanine-thymidine cross-links in DNA by peroxynitrite/carbon dioxide. Chemical research in toxicology 20110718
Age-dependent changes in 8-oxoguanine-DNA glycosylase activity are modulated by adaptive responses to physical exercise in human skeletal muscle. Free radical biology & medicine 20110715
Recent progress toward hydrogen medicine: potential of molecular hydrogen for preventive and therapeutic applications. Current pharmaceutical design 20110701
Alcohol consumption and oxidative DNA damage. International journal of environmental research and public health 20110701
Rescue of the orphan enzyme isoguanine deaminase. Biochemistry 20110628
Delayed repair of radiation induced clustered DNA damage: friend or foe? Mutation research 20110603
hOGG1 Ser326Cys polymorphism and risk of childhood acute lymphoblastic leukemia in a Chinese population. Cancer science 20110601
Vitamin E ameliorates iodine-induced cytotoxicity in thyroid. The Journal of endocrinology 20110601
DNA polymerases provide a canon of strategies for translesion synthesis past oxidatively generated lesions. Current opinion in structural biology 20110601
Porphyromonas gingivalis mutY is involved in the repair of oxidative stress-induced DNA mispairing. Molecular oral microbiology 20110601
Association of gene polymorphisms with development of cancer risk or their protective role associated with some mutant alleles. The Indian journal of medical research 20110601
Protective association exhibited by the single nucleotide polymorphism (SNP) rs1052133 in the gene human 8-oxoguanine DNA glycosylase (hOGG1) with the risk of squamous cell carcinomas of the head & neck (SCCHN) among north Indians. The Indian journal of medical research 20110601
8-Oxoguanine incision activity is impaired in lung tissues of NSCLC patients with the polymorphism of OGG1 and XRCC1 genes. Mutation research 20110510
The DNA glycosylase Ogg1 defends against oxidant-induced mtDNA damage and apoptosis in pulmonary artery endothelial cells. Free radical biology & medicine 20110501
Seed imbibition in Medicago truncatula Gaertn.: Expression profiles of DNA repair genes in relation to PEG-mediated stress. Journal of plant physiology 20110501
First evidence for digenic inheritance in hereditary colorectal cancer by mutations in the base excision repair genes. European journal of cancer (Oxford, England : 1990) 20110501
8-Hydroxyguanine levels and repair capacity during mouse embryonic stem cell differentiation. Free radical research 20110501
Oxidatively generated damage to DNA by UVA radiation in cells and human skin. The Journal of investigative dermatology 20110501
Cockayne syndrome B protein antagonizes OGG1 in modulating CAG repeat length in vivo. Aging 20110501
The impact of OGG1, MTH1 and MnSOD gene polymorphisms on 8-hydroxy-2'-deoxyguanosine and cellular superoxide dismutase activity in myocardial ischemia-reperfusion. Molecular biology reports 20110401
In vitro functional effects of XPC gene rare variants from bladder cancer patients. Carcinogenesis 20110401
Aflatoxin genotoxicity is associated with a defective DNA damage response bypassing p53 activation. Liver international : official journal of the International Association for the Study of the Liver 20110401
The 8-oxoguanine DNA N-glycosylase 1 (hOGG1) Ser326Cys variant affects the susceptibility to Graves' disease. Cell biochemistry and function 20110401
Alkylation base damage is converted into repairable double-strand breaks and complex intermediates in G2 cells lacking AP endonuclease. PLoS genetics 20110401
Interactions between catalysts and amphiphilic structures and their implications for a protocell model. Chemphyschem : a European journal of chemical physics and physical chemistry 20110314
Early host cell reactivation of an oxidatively damaged adenovirus-encoded reporter gene requires the Cockayne syndrome proteins CSA and CSB. Mutagenesis 20110301
Trypanosoma cruzi MSH2: Functional analyses on different parasite strains provide evidences for a role on the oxidative stress response. Molecular and biochemical parasitology 20110301
Mineralocorticoid receptor-mediated DNA damage in kidneys of DOCA-salt hypertensive rats. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110301
Parallel high-throughput RNA interference screens identify PINK1 as a potential therapeutic target for the treatment of DNA mismatch repair-deficient cancers. Cancer research 20110301
Combined toxic exposures and human health: biomarkers of exposure and effect. International journal of environmental research and public health 20110301
DNA damage and repair in endometrial cancer in correlation with the hOGG1 and RAD51 genes polymorphism. Molecular biology reports 20110201
Aldosterone induces oxidative stress, oxidative DNA damage and NF-κB-activation in kidney tubule cells. Molecular carcinogenesis 20110201
Oxidative DNA damage bypass in Arabidopsis thaliana requires DNA polymerase λ and proliferating cell nuclear antigen 2. The Plant cell 20110201
Reference ranges of urinary biomarkers of oxidized guanine in (2'-deoxy)ribonucleotides and nucleic acids. Free radical biology & medicine 20110115
8-Oxoguanine DNA-glycosylase repair activity and expression: a comparison between cryopreserved isolated lymphocytes and EBV-derived lymphoblastoid cell lines. Mutation research 20110110
Spontaneous mutagenesis in Csb(m/m)Ogg1⁻(/)⁻ mice is attenuated by dietary resveratrol. Carcinogenesis 20110101
Quantitative assessment of DNA damage directly in lens epithelial cells from senile cataract patients. Molecular vision 20110101
Gallbladder cancer predisposition: a multigenic approach to DNA-repair, apoptotic and inflammatory pathway genes. PloS one 20110101
Mysterious link between iron overload and CDKN2A/2B. Journal of clinical biochemistry and nutrition 20110101
Phytic Acid Protects against 6-Hydroxydopamine-Induced Dopaminergic Neuron Apoptosis in Normal and Iron Excess Conditions in a Cell Culture Model. Parkinson's disease 20110101
Analysis of the ArcA regulon in anaerobically grown Salmonella enterica sv. Typhimurium. BMC microbiology 20110101
Mitochondrial DNA damage and animal longevity: insights from comparative studies. Journal of aging research 20110101
The base excision repair pathway is required for efficient lentivirus integration. PloS one 20110101
Chronic occupational exposure to hexavalent chromium causes DNA damage in electroplating workers. BMC public health 20110101
Role of mutagenicity in asbestos fiber-induced carcinogenicity and other diseases. Journal of toxicology and environmental health. Part B, Critical reviews 20110101
Inactivation of the DNA repair genes mutS, mutL or the anti-recombination gene mutS2 leads to activation of vitamin B1 biosynthesis genes. PloS one 20110101
Dose-dependent onset of regenerative program in neutron irradiated mouse skin. PloS one 20110101
Metabolism, genomics, and DNA repair in the mouse aging liver. Current gerontology and geriatrics research 20110101
NNK-Induced Lung Tumors: A Review of Animal Model. Journal of oncology 20110101
Salivary 8-OHdG Induction by Physical Exercise Training Under Food Restriction. The open dentistry journal 20110101
Mechanism of recognition and repair of damaged DNA by human 8-oxoguanine DNA glycosylase hOGG1. Biochemistry. Biokhimiia 20110101
Reduction in oxidatively generated DNA damage following smoking cessation. Tobacco induced diseases 20110101
Oxidative damage DNA: 8-oxoGua and 8-oxodG as molecular markers of cancer. Medical science monitor : international medical journal of experimental and clinical research 20110101
Assessment of the genetic risks of a metallic alloy used in medical implants. Genetics and molecular biology 20110101
Synchronization of cytoplasmic and transferred mitochondrial ribosomal protein gene expression in land plants is linked to Telo-box motif enrichment. BMC evolutionary biology 20110101
Association between urinary excretion of cortisol and markers of oxidatively damaged DNA and RNA in humans. PloS one 20110101
Therapeutic effects of hydrogen in animal models of Parkinson's disease. Parkinson's disease 20110101
Adenylate kinase 3 sensitizes cells to cigarette smoke condensate vapor induced cisplatin resistance. PloS one 20110101
Mitochondrial therapeutics in Alzheimer's disease and Parkinson's disease. Alzheimer's research & therapy 20110101
Alterations in DNA repair gene expression and their possible regulation in rat-liver regeneration. Genetics and molecular biology 20110101
Is the GSTM1 null polymorphism a risk factor in primary open angle glaucoma? Molecular vision 20110101
Ribosomal protein s3: a multifunctional target of attaching/effacing bacterial pathogens. Frontiers in microbiology 20110101
Molecular and cellular pathways associated with chromosome 1p deletions during colon carcinogenesis. Clinical and experimental gastroenterology 20110101
Oxidative DNA Damage in Blood of CVD Patients Taking Detralex. The open cardiovascular medicine journal 20110101
The hOGG1 Ser326Cys polymorphism and prostate cancer risk: a meta-analysis of 2584 cases and 3234 controls. BMC cancer 20110101
RNA oxidation adducts 8-OHG and 8-OHA change with Aβ42 levels in late-stage Alzheimer's disease. PloS one 20110101
Unique Properties of Hepatocarcinogenesis-Resistant DRH Rat Hepatocytes Linked or Not Linked to the Drh1 Locus on Rat Chromosome 1. International journal of hepatology 20110101
Characterization of a Mycobacterium smegmatis uvrA mutant impaired in dormancy induced by hypoxia and low carbon concentration. BMC microbiology 20110101
Pharmaceutical and nutraceutical effects of Pinus pinaster bark extract. Research in pharmaceutical sciences 20110101
Anti-inflammatory drugs reduce the risk of hepatocellular carcinoma development. ISRN oncology 20110101
The effect of hOGG1 Ser326Cys polymorphism on cancer risk: evidence from a meta-analysis. PloS one 20110101
Biological sensors for solar ultraviolet radiation. Sensors (Basel, Switzerland) 20110101
Visible light may directly induce nuclear DNA damage triggering the death pathway in RGC-5 cells. Molecular vision 20110101
Earthworms and soil pollutants. Sensors (Basel, Switzerland) 20110101
Fernblock, a nutriceutical with photoprotective properties and potential preventive agent for skin photoaging and photoinduced skin cancers. International journal of molecular sciences 20110101
Nanopore detection of 8-oxo-7,8-dihydro-2'-deoxyguanosine in immobilized single-stranded DNA via adduct formation to the DNA damage site. Journal of the American Chemical Society 20101229
Human proteins that specifically bind to 8-oxoguanine-containing RNA and their responses to oxidative stress. Biochemical and biophysical research communications 20101210
Programmed cell death triggered by nucleotide pool damage and its prevention by MutT homolog-1 (MTH1) with oxidized purine nucleoside triphosphatase. Mutation research 20101128
DNA polymerase structure-based insight on the mutagenic properties of 8-oxoguanine. Mutation research 20101128
Salvage of oxidized guanine derivatives in the (2'-deoxy)ribonucleotide pool as source of mutations in DNA. Mutation research 20101128
The Friedreich's ataxia protein frataxin modulates DNA base excision repair in prokaryotes and mammals. The Biochemical journal 20101115
Structural basis for error-free replication of oxidatively damaged DNA by yeast DNA polymerase η. Structure (London, England : 1993) 20101110
Non-additive interactions of nucleobases in model dinucleotide steps occurring in B-DNA crystals. Journal of molecular modeling 20101101
Impact of histone deacetylase inhibitors SAHA and MS-275 on DNA repair pathways in human mesenchymal stem cells. Journal of cellular physiology 20101101
Adenine DNA glycosylase activity of 14 human MutY homolog (MUTYH) variant proteins found in patients with colorectal polyposis and cancer. Human mutation 20101101
Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examples. Archives of toxicology 20101101
Asian dust and titanium dioxide particles-induced inflammation and oxidative DNA damage in C57BL/6 mice. Inhalation toxicology 20101101
Sensitive voltammetric sensor for the determination of oxidative DNA damage in calf thymus DNA. Biosensors & bioelectronics 20101015
Photosensitization induced by the antibacterial fluoroquinolone Rufloxacin leads to mutagenesis in yeast. Mutation research 20101013
Mechanism of genotoxicity induced by targeted cytoplasmic irradiation. British journal of cancer 20101012
Ser 524 is a phosphorylation site in MUTYH and Ser 524 mutations alter 8-oxoguanine (OG): a mismatch recognition. DNA repair 20101005
Substitution of Ala for Tyr567 in RB69 DNA polymerase allows dAMP and dGMP to be inserted opposite Guanidinohydantoin . Biochemistry 20101005
regT can modulate gingipain activity and response to oxidative stress in Porphyromonas gingivalis. Microbiology (Reading, England) 20101001
Age-related motor neuron degeneration in DNA repair-deficient Ercc1 mice. Acta neuropathologica 20101001
Structure of a putative NTP pyrophosphohydrolase: YP_001813558.1 from Exiguobacterium sibiricum 255-15. Acta crystallographica. Section F, Structural biology and crystallization communications 20101001
Genomic damage in endstage renal disease-contribution of uremic toxins. Toxins 20101001
UVA activation of N-dialkylnitrosamines releasing nitric oxide, producing strand breaks as well as oxidative damages in DNA, and inducing mutations in the Ames test. Mutation research 20100910
Epithelial ablation of Bcl-XL increases sensitivity to oxygen without disrupting lung development. American journal of respiratory cell and molecular biology 20100901
Oxidative stress and 8-oxoguanine repair are enhanced in colon adenoma and carcinoma patients. Mutagenesis 20100901
Genome-scale approaches to investigate oxidative DNA damage. Journal of clinical biochemistry and nutrition 20100901
8-Oxo-7,8-dihydroguanine: links to gene expression, aging, and defense against oxidative stress. Free radical biology & medicine 20100815
Oxidative damage to DNA and lipids as biomarkers of exposure to air pollution. Environmental health perspectives 20100801
Effect of 8-oxoguanine and abasic site DNA lesions on in vitro elongation by human DNA polymerase in the presence of replication protein A and proliferating-cell nuclear antigen. The Biochemical journal 20100801
Saccharomyces cerevisiae-based system for studying clustered DNA damages. Radiation and environmental biophysics 20100801
Cockayne syndrome group B protein promotes mitochondrial DNA stability by supporting the DNA repair association with the mitochondrial membrane. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20100701
Role of vimA in cell surface biogenesis in Porphyromonas gingivalis. Microbiology (Reading, England) 20100701
Spectrum of HNF1A somatic mutations in hepatocellular adenoma differs from that in patients with MODY3 and suggests genotoxic damage. Diabetes 20100701
The tyrosyl-DNA phosphodiesterase gene family in Medicago truncatula Gaertn.: bioinformatic investigation and expression profiles in response to copper- and PEG-mediated stress. Planta 20100701
Dynamic flexibility of DNA repair pathways in growth arrested Escherichia coli. DNA repair 20100701
Detection of damaged DNA bases by DNA glycosylase enzymes. Biochemistry 20100622
The oxidation of 8-oxo-7,8-dihydroguanine by iodine. Bioorganic & medicinal chemistry letters 20100615
Oxygen as a friend and enemy: How to combat the mutational potential of 8-oxo-guanine. DNA repair 20100604
Functional analysis of MUTYH mutated proteins associated with familial adenomatous polyposis. DNA repair 20100604
Electrochemical oxidation of guanine: electrode reaction mechanism and tailoring carbon electrode surfaces to switch between adsorptive and diffusional responses. The journal of physical chemistry. B 20100603
Exposure to metal-rich particulate matter modifies the expression of candidate microRNAs in peripheral blood leukocytes. Environmental health perspectives 20100601
Biomarkers of lead exposure and DNA methylation within retrotransposons. Environmental health perspectives 20100601
Enzymatic recognition of DNA damage induced by UVB-photosensitized titanium dioxide and biological consequences in Saccharomyces cerevisiae: evidence for oxidatively DNA damage generation. Mutation research 20100601
Measurement of oxidatively generated base damage in cellular DNA and urine. Free radical biology & medicine 20100601
Oxidative DNA damage and repair in teratogenesis and neurodevelopmental deficits. Birth defects research. Part C, Embryo today : reviews 20100601
Substitution of Ala for Tyr567 in RB69 DNA polymerase allows dAMP to be inserted opposite 7,8-dihydro-8-oxoguanine . Biochemistry 20100518
Oxidation of 8-oxo-7,8-dihydro-2'-deoxyguanosine by oxyl radicals produced by photolysis of azo compounds. Chemical research in toxicology 20100517
Aging and oxidatively damaged nuclear DNA in animal organs. Free radical biology & medicine 20100515
Effects of base excision repair proteins on mutagenesis by 8-oxo-7,8-dihydroguanine (8-hydroxyguanine) paired with cytosine and adenine. DNA repair 20100504
Quantitative determination of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine, 8-oxo-7,8-dihydroguanine, 8-oxo-7,8-dihydroguanosine, and their non-oxidized forms: daily concentration profile in healthy volunteers. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20100501
A MATE-family efflux pump rescues the Escherichia coli 8-oxoguanine-repair-deficient mutator phenotype and protects against H(2)O(2) killing. PLoS genetics 20100501
Characterization of oxidative guanine damage and repair in mammalian telomeres. PLoS genetics 20100501
Effects of valproate, carbamazepine, and levetiracetam on the antioxidant and oxidant systems in epileptic patients and their clinical importance. Clinical neuropharmacology 20100501
Molecular dynamics simulation of 8-oxoguanine containing DNA fragments reveals altered hydration and ion binding patterns. The journal of physical chemistry. B 20100415
Trypanosoma cruzi induces the reactive oxygen species-PARP-1-RelA pathway for up-regulation of cytokine expression in cardiomyocytes. The Journal of biological chemistry 20100409
SECIS-binding protein 2 promotes cell survival by protecting against oxidative stress. Antioxidants & redox signaling 20100401
OGG1 is a novel prognostic indicator in acute myeloid leukaemia. Oncogene 20100401
Octyl methoxycinnamate modulates gene expression and prevents cyclobutane pyrimidine dimer formation but not oxidative DNA damage in UV-exposed human cell lines. Toxicological sciences : an official journal of the Society of Toxicology 20100401
Occupational exposure to low levels of benzene: Biomarkers of exposure and nucleic acid oxidation and their modulation by polymorphic xenobiotic metabolizing enzymes. Toxicology letters 20100401
Roles of specialized DNA polymerases in mutagenesis by 8-hydroxyguanine in human cells. Mutation research 20100401
[The influence of oxidized DNA on mammalian genome]. Fukuoka igaku zasshi = Hukuoka acta medica 20100401
Kinetics of mismatch formation opposite lesions by the replicative DNA polymerase from bacteriophage RB69. Biochemistry 20100323
Crystal structure of a replicative DNA polymerase bound to the oxidized guanine lesion guanidinohydantoin. Biochemistry 20100323
The C-terminal lysine of Ogg2 DNA glycosylases is a major molecular determinant for guanine/8-oxoguanine distinction. Journal of molecular biology 20100319
Spontaneous and radiation-induced chromosomal instability and persistence of chromosome aberrations after radiotherapy in lymphocytes from prostate cancer patients. Radiation and environmental biophysics 20100301
An ECVAG trial on assessment of oxidative damage to DNA measured by the comet assay. Mutagenesis 20100301
Hierarchy of lesion processing governs the repair, double-strand break formation and mutability of three-lesion clustered DNA damage. Nucleic acids research 20100301
Atm-deficient mice exhibit increased sensitivity to dextran sulfate sodium-induced colitis characterized by elevated DNA damage and persistent immune activation. Cancer research 20100301
A two-tiered compensatory response to loss of DNA repair modulates aging and stress response pathways. Aging 20100301
The hunt for 8-oxoguanine deaminase. Journal of the American Chemical Society 20100217
Oxidation of DNA: damage to nucleobases. Accounts of chemical research 20100216
Evidence for the involvement of DNA repair enzyme NEIL1 in nucleotide excision repair of (5'R)- and (5'S)-8,5'-cyclo-2'-deoxyadenosines. Biochemistry 20100216
Influence of substrate complexity on the diastereoselective formation of spiroiminodihydantoin and guanidinohydantoin from chromate oxidation. Chemical research in toxicology 20100215
The oxidative DNA glycosylases of Mycobacterium tuberculosis exhibit different substrate preferences from their Escherichia coli counterparts. DNA repair 20100204
Use of a molecular beacon to track the activity of base excision repair protein OGG1 in live cells. DNA repair 20100204
MUTYH mutations associated with familial adenomatous polyposis: functional characterization by a mammalian cell-based assay. Human mutation 20100201
Metallothionein-I + II and receptor megalin are altered in relation to oxidative stress in cerebral lymphomas. Leukemia & lymphoma 20100201
Novel molecular insights into the mechanism of GO removal by MutM. Cell research 20100201
Exposure to 1800 MHz radiofrequency radiation induces oxidative damage to mitochondrial DNA in primary cultured neurons. Brain research 20100122
Deletion of Ogg1 DNA glycosylase results in telomere base damage and length alteration in yeast. The EMBO journal 20100120
A liquid chromatography-mass spectrometric assay for measuring activity of human 8-oxoguanine-DNA glycosylase. Analytical biochemistry 20100115
Entrapment and structure of an extrahelical guanine attempting to enter the active site of a bacterial DNA glycosylase, MutM. The Journal of biological chemistry 20100108
Effects of cryopreservation on human sperm deoxyribonucleic acid integrity. Fertility and sterility 20100101
Simultaneous determination in situ of DNA fragmentation and 8-oxoguanine in human sperm. Fertility and sterility 20100101
A distinct physiological role of MutY in mutation prevention in mycobacteria. Microbiology (Reading, England) 20100101
Urinary analysis of 8-oxo-7,8-dihydroguanine and 8-oxo-7,8-dihydro-2'-deoxyguanosine by isotope-dilution LC-MS/MS with automated solid-phase extraction: Study of 8-oxo-7,8-dihydroguanine stability. Free radical biology & medicine 20100101
Structural and dynamic features of the MutT protein in the recognition of nucleotides with the mutagenic 8-oxoguanine base. The Journal of biological chemistry 20100101
Exposure assessment of PM2.5 and urinary 8-OHdG for diesel exhaust emission inspector. The Science of the total environment 20100101
The effect of oxidative stress on nucleotide-excision repair in colon tissue of newborn piglets. Mutation research 20100101
Analysis of the contribution of charge transport in iodine-125-induced DNA damage. Radiation research 20100101
Effect of quadruplex conformation on radiation-induced formation of 8-hydroxyguanine and unaltered base release in polyguanylic acid. Radiation research 20100101
Folate deficiency alters hepatic and colon MGMT and OGG-1 DNA repair protein expression in rats but has no effect on genome-wide DNA methylation. Cancer prevention research (Philadelphia, Pa.) 20100101
Endonuclease IV is the main base excision repair enzyme involved in DNA damage induced by UVA radiation and stannous chloride. Journal of biomedicine & biotechnology 20100101
Selenoprotein P controls oxidative stress in cornea. PloS one 20100101
Adenine oxidation by pyrite-generated hydroxyl radicals. Geochemical transactions 20100101
Long-term progestin contraceptives (LTPOC) induce aberrant angiogenesis, oxidative stress and apoptosis in the guinea pig uterus: A model for abnormal uterine bleeding in humans. Journal of angiogenesis research 20100101
Targeting EGFR induced oxidative stress by PARP1 inhibition in glioblastoma therapy. PloS one 20100101
Oxidative stress mediates the pathogenic effect of different Alzheimer's disease risk factors. Frontiers in aging neuroscience 20100101
XRCC1, but not APE1 and hOGG1 gene polymorphisms is a risk factor for pterygium. Molecular vision 20100101
Oxidative stress and DNA methylation in prostate cancer. Obstetrics and gynecology international 20100101
The Mutyh base excision repair gene influences the inflammatory response in a mouse model of ulcerative colitis. PloS one 20100101
Redox regulation in cancer: a double-edged sword with therapeutic potential. Oxidative medicine and cellular longevity 20100101
Rapid method for determination of DNA repair capacity in human peripheral blood lymphocytes amongst smokers. BMC cancer 20100101
Selective Incision of the alpha-N-Methyl-Formamidopyrimidine Anomer by Escherichia coli Endonuclease IV. Journal of nucleic acids 20100101
Pre-Steady-State Kinetic Analysis of Truncated and Full-Length Saccharomyces cerevisiae DNA Polymerase Eta. Journal of nucleic acids 20100101
Evolutionary loss of 8-oxo-G repair components among eukaryotes. Genome integrity 20100101
New evidence on iron, copper accumulation and zinc depletion and its correlation with DNA integrity in aging human brain regions. Indian journal of psychiatry 20100101
A study of association between expression of hOGG1, VDAC1, HK-2 and cervical carcinoma. Journal of experimental & clinical cancer research : CR 20100101
Age-associated modifications of Base Excision Repair activities in human skin fibroblast extracts. Mechanisms of ageing and development 20100101
Mechanistic Studies with DNA Polymerases Reveal Complex Outcomes following Bypass of DNA Damage. Journal of nucleic acids 20100101
Elevated Levels of DNA Strand Breaks Induced by a Base Analog in the Human Cell Line with the P32T ITPA Variant. Journal of nucleic acids 20100101
Early Steps in the DNA Base Excision Repair Pathway of a Fission Yeast Schizosaccharomyces pombe. Journal of nucleic acids 20100101
Characterization of a Y-Family DNA Polymerase eta from the Eukaryotic Thermophile Alvinella pompejana. Journal of nucleic acids 20100101
Architecture of y-family DNA polymerases relevant to translesion DNA synthesis as revealed in structural and molecular modeling studies. Journal of nucleic acids 20100101
Error-Prone Translesion DNA Synthesis by Escherichia coli DNA Polymerase IV (DinB) on Templates Containing 1,2-dihydro-2-oxoadenine. Journal of nucleic acids 20100101
Overview of DNA Repair in Trypanosoma cruzi, Trypanosoma brucei, and Leishmania major. Journal of nucleic acids 20100101
Molecular mechanisms of the whole DNA repair system: a comparison of bacterial and eukaryotic systems. Journal of nucleic acids 20100101
Lung cancer risk and genetic polymorphisms in DNA repair pathways: a meta-analysis. Journal of nucleic acids 20100101
Cu,Zn-superoxide dismutase deficiency in mice leads to organ-specific increase in oxidatively damaged DNA and NF-κB1 protein activity. Acta biochimica Polonica 20100101
The ERCC6 gene and age-related macular degeneration. PloS one 20100101
8-oxo-7,8-dihydro-2'-deoxyguanosine as a biomarker of oxidative damage in oesophageal cancer patients: lack of association with antioxidant vitamins and polymorphism of hOGG1 and GST. Journal of experimental & clinical cancer research : CR 20100101
α-Synuclein and DJ-1 as potential biological fluid biomarkers for Parkinson's Disease. International journal of molecular sciences 20100101
Evidence of altered DNA integrity in the brain regions of suicidal victims of Bipolar Depression. Indian journal of psychiatry 20100101
How does pycnogenol® influence oxidative damage to DNA and its repair ability in elderly people? Prague medical report 20100101
Kinetic approaches to understanding the mechanisms of fidelity of the herpes simplex virus type 1 DNA polymerase. Journal of nucleic acids 20100101
Molecular mechanisms of ultraviolet radiation-induced DNA damage and repair. Journal of nucleic acids 20100101
The biological and metabolic fates of endogenous DNA damage products. Journal of nucleic acids 20100101
What can surrogate tissues tell us about the oxidative stress status of the prostate? A hypothesis-generating in-vivo study. PloS one 20100101
Genotoxic effect induced by hydrogen peroxide in human hepatoma cells using comet assay. The Libyan journal of medicine 20100101
Non-homologous DNA end joining in normal and cancer cells and its dependence on break structures. Genetics and molecular biology 20100101
Radiation-induced biomarkers for the detection and assessment of absorbed radiation doses. Journal of pharmacy & bioallied sciences 20100101
Analysis of an anomalous mutant of MutM DNA glycosylase leads to new insights into the catalytic mechanism. Journal of the American Chemical Society 20091230
Solvent effects on ionization potentials of guanine runs and chemically modified guanine in duplex DNA: effect of electrostatic interaction and its reduction due to solvent. The journal of physical chemistry. B 20091224
Age-related alterations in the expression of MTH2 in the hippocampus of the SAMP8 mouse with learning and memory deterioration. Journal of the neurological sciences 20091215
Encounter and extrusion of an intrahelical lesion by a DNA repair enzyme. Nature 20091210
Reversible chemical step and rate-limiting enzyme regeneration in the reaction catalyzed by formamidopyrimidine-DNA glycosylase. Biochemistry 20091208
Apex1 can cleave complex clustered DNA lesions in cells. DNA repair 20091203
alpha-MSH activates immediate defense responses to UV-induced oxidative stress in human melanocytes. Pigment cell & melanoma research 20091201
Effects of 7,8-dihydro-8-oxo-deoxyguanosine on antigen challenge in ovalbumin-sensitized mice may be mediated by suppression of Rac. British journal of pharmacology 20091201
hOGG1 Ser326Cys polymorphism and risk of lung cancer by histological type. Journal of human genetics 20091201
Do mtDNA Mutations Participate in the Pathogenesis of Sporadic Parkinson's Disease? Current genomics 20091201
No Modifying Effect of Antioxidant N-Acetyl-L-Cysteine on Fenofibrate-induced Hepatocarcinogenesis in Rats. Journal of toxicologic pathology 20091201
Molecular basis of transcriptional mutagenesis at 8-oxoguanine. The Journal of biological chemistry 20091113
Comparison of isoelectronic 8-HO-G and 8-NH2-G derivatives in redox processes. Journal of the American Chemical Society 20091104
Structural basis for the lack of opposite base specificity of Clostridium acetobutylicum 8-oxoguanine DNA glycosylase. DNA repair 20091102
Accumulation of 8-oxoguanine in liver DNA during hyperoxic resuscitation of newborn mice. Pediatric research 20091101
Sources of extracellular, oxidatively-modified DNA lesions: implications for their measurement in urine. Journal of clinical biochemistry and nutrition 20091101
Stochastic drift in mitochondrial DNA point mutations: a novel perspective ex silico. PLoS computational biology 20091101
Contribution of glutathione status to oxidant-induced mitochondrial DNA damage in colonic epithelial cells. Free radical biology & medicine 20091015
Urinary excretion of biomarkers of oxidatively damaged DNA and RNA in hereditary hemochromatosis. Free radical biology & medicine 20091015
Coordination between polymerase beta and FEN1 can modulate CAG repeat expansion. The Journal of biological chemistry 20091009
Biomarkers of nucleic acid oxidation, polymorphism in, and expression of, hOGG1 gene in styrene-exposed workers. Toxicology letters 20091008
Biological consequences of potential repair intermediates of clustered base damage site in Escherichia coli. Mutation research 20091002
Repair activities of human 8-oxoguanine DNA glycosylase are stimulated by the interaction with human checkpoint sensor Rad9-Rad1-Hus1 complex. DNA repair 20091002
Ribosomal protein S3: A multi-functional protein that interacts with both p53 and MDM2 through its KH domain. DNA repair 20091002
Chronic alcohol consumption prevents 8-hydroxyguanine accumulation in 3'-methyl-4-dimethylaminoazobenzene-treated mouse liver. Biochemical and biophysical research communications 20090918
Peculiarities of the antioxidant and radioprotective effects of hydrated C60 fullerene nanostuctures in vitro and in vivo. Free radical biology & medicine 20090915
Direct and indirect roles of RECQL4 in modulating base excision repair capacity. Human molecular genetics 20090915
Modulation of DNA glycosylase activities in mesenchymal stem cells. Experimental cell research 20090910
Interaction of human DNA polymerase alpha and DNA polymerase I from Bacillus stearothermophilus with hypoxanthine and 8-oxoguanine nucleotides. Biochemistry 20090901
Formation of spiroiminodihydantoin nucleoside from 8-oxo-7,8-dihydro-2'-deoxyguanosine by nitric oxide under aerobic conditions. Bioorganic & medicinal chemistry letters 20090901
Substrate specificity and excision kinetics of natural polymorphic variants and phosphomimetic mutants of human 8-oxoguanine-DNA glycosylase. The FEBS journal 20090901
Structural and functional analysis of Sulfolobus solfataricus Y-family DNA polymerase Dpo4-catalyzed bypass of the malondialdehyde-deoxyguanosine adduct. Biochemistry 20090804
A study of pyrimidine base damage in relation to oxidative stress and cancer. British journal of cancer 20090804
Investigation of effects of Lacidipine, Ramipril and Valsartan on DNA damage and oxidative stress occurred in acute and chronic periods following isoproterenol-induced myocardial infarct in rats. Molecular and cellular biochemistry 20090801
Blackcurrant seed press residue increases tocopherol concentrations in serum and stool whilst biomarkers in stool and urine indicate increased oxidative stress in human subjects. The British journal of nutrition 20090801
Structure-dependent DNA damage and repair in a trinucleotide repeat sequence. Biochemistry 20090721
Explorative study to identify novel candidate genes related to oxaliplatin efficacy and toxicity using a DNA repair array. British journal of cancer 20090721
African swine fever virus AP endonuclease is a redox-sensitive enzyme that repairs alkylating and oxidative damage to DNA. Virology 20090720
Targeted deletion of the genes encoding NTH1 and NEIL1 DNA N-glycosylases reveals the existence of novel carcinogenic oxidative damage to DNA. DNA repair 20090704
Mutational studies of Pa-AGOG DNA glycosylase from the hyperthermophilic crenarchaeon Pyrobaculum aerophilum. DNA repair 20090704
FANCJ helicase uniquely senses oxidative base damage in either strand of duplex DNA and is stimulated by replication protein A to unwind the damaged DNA substrate in a strand-specific manner. The Journal of biological chemistry 20090703
Electrostatic potential maps of damaged DNA studied by image analysis tools. 8-Oxoguanine and abasic site lesions. Journal of molecular modeling 20090701
Impact of radiotherapy and chemotherapy on biomarkers of oxidative DNA damage in lung cancer patients. Clinical biochemistry 20090701
Catalytically impaired hMYH and NEIL1 mutant proteins identified in patients with primary sclerosing cholangitis and cholangiocarcinoma. Carcinogenesis 20090701
Local and systemic oxidant/antioxidant status before and during lung cancer radiotherapy. Free radical research 20090701
Processing of thymine glycol in a clustered DNA damage site: mutagenic or cytotoxic. Nucleic acids research 20090701
Characterization of the major formamidopyrimidine-DNA glycosylase homolog in Mycobacterium tuberculosis and its linkage to variable tandem repeats. FEMS immunology and medical microbiology 20090701
Sensitized formation of oxidatively generated damage to cellular DNA by UVA radiation. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20090701
Origin of an alternative genetic code in the extremely small and GC-rich genome of a bacterial symbiont. PLoS genetics 20090701
Transcriptional mutagenesis induced by 8-oxoguanine in mammalian cells. PLoS genetics 20090701
DNA repair efficiency in transgenic mice over expressing ribosomal protein S3. Mutation research 20090618
Up-regulation of myocardial DNA base excision repair activities in experimental heart failure. Mutation research 20090618
Glutathione depletion by buthionine sulfoximine induces oxidative damage to DNA in organs of rabbits in vivo. Biochemistry 20090609
Structural and energetic heterogeneities of canonical and oxidized central guanine triad of B-DNA telomeric fragments. Journal of molecular modeling 20090601
Absolute configurations of spiroiminodihydantoin and allantoin stereoisomers: comparison of computed and measured electronic circular dichroism spectra. Chemical research in toxicology 20090601
Analysis of 7,8-dihydro-8-oxo-2'-deoxyguanosine in cellular DNA during oxidative stress. Chemical research in toxicology 20090518
Role of MUTYH and MSH2 in the control of oxidative DNA damage, genetic instability, and tumorigenesis. Cancer research 20090515
Flexibility promotes fidelity. Structure (London, England : 1993) 20090513
Crystal structures of two archaeal 8-oxoguanine DNA glycosylases provide structural insight into guanine/8-oxoguanine distinction. Structure (London, England : 1993) 20090513
Impact of conformational heterogeneity of OxoG lesions and their pairing partners on bypass fidelity by Y family polymerases. Structure (London, England : 1993) 20090513
Plant and fungal Fpg homologs are formamidopyrimidine DNA glycosylases but not 8-oxoguanine DNA glycosylases. DNA repair 20090501
Globular adiponectin-induced RAW 264 apoptosis is regulated by a reactive oxygen species-dependent pathway involving Bcl-2. Free radical biology & medicine 20090501
Serendipitous findings while researching oxygen free radicals. Free radical biology & medicine 20090415
Cockayne syndrome group B protein stimulates repair of formamidopyrimidines by NEIL1 DNA glycosylase. The Journal of biological chemistry 20090403
Peroxiredoxin 4 knockout results in elevated spermatogenic cell death via oxidative stress. The Biochemical journal 20090401
TEGDMA-induced oxidative DNA damage and activation of ATM and MAP kinases. Biomaterials 20090401
Enhancement of lung carcinogenesis initiated with 4-(N-hydroxymethylnitrosamino)-1-(3-pyridyl)-1-butanone by Ogg1 gene deficiency in female, but not male, mice. The Journal of toxicological sciences 20090401
DNA oxidation: investigating its key role in environmental mutagenesis with the comet assay. Mutation research 20090331
Polynucleotide phosphorylase protects Escherichia coli against oxidative stress. Biochemistry 20090310
An emissive C analog distinguishes between G, 8-oxoG, and T. Organic letters 20090305
Toward a molecular equivalent dose: use of the medaka model in comparative risk assessment. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20090301
Msh1p counteracts oxidative lesion-induced instability of mtDNA and stimulates mitochondrial recombination in Saccharomyces cerevisiae. DNA repair 20090301
8-Oxoguanine DNA glycosylase (Ogg1) causes a transcriptional inactivation of damaged DNA in the absence of functional Cockayne syndrome B (Csb) protein. DNA repair 20090301
The DNA repair protein NBS1 influences the base excision repair pathway. Carcinogenesis 20090301
The oxidative stress response is region specific in organogenesis stage mouse embryos exposed to 5-bromo-2'-deoxyuridine. Birth defects research. Part A, Clinical and molecular teratology 20090301
In vitro replication and repair studies of tandem lesions containing neighboring thymidine glycol and 8-oxo-7,8-dihydro-2'-deoxyguanosine. Chemical research in toxicology 20090301
Polymorphisms of the DNA base excision repair gene MUTYH in head and neck cancer. Experimental oncology 20090301
Oxidative stress biomarkers and lifestyles in Japanese healthy people. Journal of clinical biochemistry and nutrition 20090301
Activated toxicity of diesel particulate extract by ultraviolet a radiation in mammalian cells: role of singlet oxygen. Environmental health perspectives 20090301
Targeting the progression of Parkinson's disease. Current neuropharmacology 20090301
Sod2 haploinsufficiency does not accelerate aging of telomere dysfunctional mice. Aging 20090301
Biological Basis of Differential Susceptibility to Hepatocarcinogenesis among Mouse Strains. Journal of toxicologic pathology 20090301
Impact of 7,8-dihydro-8-oxoguanine on methylation of the CpG site by Dnmt3a. Biochemistry 20090217
The carotenoid beta-cryptoxanthin stimulates the repair of DNA oxidation damage in addition to acting as an antioxidant in human cells. Carcinogenesis 20090201
Selective fluorescence quenching of the 8-oxoG-clamp by 8-oxodeoxyguanosine in ODN. Bioorganic & medicinal chemistry letters 20090201
Translesion DNA synthesis by human DNA polymerase eta on templates containing a pyrimidopurinone deoxyguanosine adduct, 3-(2'-deoxy-beta-d-erythro-pentofuranosyl)pyrimido-[1,2-a]purin-10(3H)-one. Biochemistry 20090120
UV-inducible base excision repair of oxidative damaged DNA in human cells. Mutagenesis 20090101
Base excision repair of oxidative DNA damage and association with cancer and aging. Carcinogenesis 20090101
Excision of the oxidatively formed 5-hydroxyhydantoin and 5-hydroxy-5-methylhydantoin pyrimidine lesions by Escherichia coli and Saccharomyces cerevisiae DNA N-glycosylases. Biochimica et biophysica acta 20090101
DNA polymerase kappa from Trypanosoma cruzi localizes to the mitochondria, bypasses 8-oxoguanine lesions and performs DNA synthesis in a recombination intermediate. Molecular microbiology 20090101
Postmortem miscoding lesions in sequence analysis of human ancient mitochondrial DNA. Journal of molecular evolution 20090101
Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases. BMC medical genomics 20090101
Characterization of the meningococcal DNA glycosylase Fpg involved in base excision repair. BMC microbiology 20090101
Acute exercise and oxidative stress: a 30 year history. Dynamic medicine : DM 20090101
Requirement for abasic endonuclease gene homologues in Arabidopsis seed development. PloS one 20090101
8-Oxo-7,8-dihydro-2'-deoxyguanosine Forms a Relatively Unstable Tetrameric Structure Compared with 2'-Deoxyguanosine. Journal of clinical biochemistry and nutrition 20090101
ATM localization and gene expression in the adult mouse eye. Molecular vision 20090101
Alveolar epithelial and endothelial cell apoptosis in emphysema: what we know and what we need to know. International journal of chronic obstructive pulmonary disease 20090101
Apoptosis and telomeres shortening related to HIV-1 induced oxidative stress in an astrocytoma cell line. BMC neuroscience 20090101
Structure of human DNA polymerase kappa inserting dATP opposite an 8-OxoG DNA lesion. PloS one 20090101
Expression of 8-oxoguanine DNA glycosylase (Ogg1) in mouse retina. Molecular vision 20090101
Quantitative analysis of oxidized guanine, 8-oxoguanine, in mitochondrial DNA by immunofluorescence method. Methods in molecular biology (Clifton, N.J.) 20090101
Construction and characterization of a cell line deficient in repair of mitochondrial, but not nuclear, oxidative DNA damage. Methods in molecular biology (Clifton, N.J.) 20090101
Preventive effect of the flavonoid, quercetin, on hepatic cancer in rats via oxidant/antioxidant activity: molecular and histological evidences. Journal of experimental & clinical cancer research : CR 20090101
Insights into the role of Val45 and Gln182 of Escherichia coli MutY in DNA substrate binding and specificity. BMC biochemistry 20090101
Molecular analysis of the APC and MUTYH genes in Galician and Catalonian FAP families: a different spectrum of mutations? BMC medical genetics 20090101
DNA damage induces nuclear translocation of parkin. Journal of biomedical science 20090101
Mutation analysis of Rad18 in human cancer cell lines and non small cell lung cancer tissues. Journal of experimental & clinical cancer research : CR 20090101
Genotoxicity of nano/microparticles in in vitro micronuclei, in vivo comet and mutation assay systems. Particle and fibre toxicology 20090101
One-electron oxidation of DNA: mechanism and consequences. Nucleic acids symposium series (2004) 20090101
Parkinson's disease brain mitochondria have impaired respirasome assembly, age-related increases in distribution of oxidative damage to mtDNA and no differences in heteroplasmic mtDNA mutation abundance. Molecular neurodegeneration 20090101
Familial adenomatous polyposis. Orphanet journal of rare diseases 20090101
Endogenous melatonin and oxidatively damaged guanine in DNA. BMC endocrine disorders 20090101
DNA damage/repair and polymorphism of the hOGG1 gene in lymphocytes of AMD patients. Journal of biomedicine & biotechnology 20090101
Effect of hyperoxidized guanine on DNA primer-template structures: spiroiminodihydantoin leads to strand slippage. FEBS letters 20081224
Formamidopyrimidines in DNA: mechanisms of formation, repair, and biological effects. Free radical biology & medicine 20081215
The association of OGG1 Ser326Cys polymorphism and urinary 8-OHdG levels with lung cancer susceptibility: a hospital-based case-control study in Turkey. Arhiv za higijenu rada i toksikologiju 20081201
Angiotensin II induces DNA damage in the kidney. Cancer research 20081115
Deficient repair of 8-hydroxyguanine in the BxPC-3 pancreatic cancer cell line. Biochemical and biophysical research communications 20081114
Influence of neighbouring base sequences on the mutagenesis induced by 7,8-dihydro-8-oxoguanine in yeast. Mutagenesis 20081101
Enhancement of apoptotic damage of squamous cell carcinoma cells by inhibition of the mitochondrial DNA repairing system. Cancer science 20081101
A role for oxidized DNA precursors in Huntington's disease-like striatal neurodegeneration. PLoS genetics 20081101
Small field radiotherapy of head and neck cancer patients is responsible for oxidatively damaged DNA/oxidative stress on the level of a whole organism. International journal of cancer 20081015
Effects of the bacterial transcription-repair coupling factor during transcription of DNA containing non-bulky lesions. DNA repair 20081001
Extremely low frequency magnetic fields cause oxidative DNA damage in rats. International journal of radiation biology 20081001
The tumor suppressor homolog in fission yeast, myh1(+), displays a strong interaction with the checkpoint gene rad1(+). Mutation research 20080926
Oxoguanine glycosylase 1 protects against methamphetamine-enhanced fetal brain oxidative DNA damage and neurodevelopmental deficits. The Journal of neuroscience : the official journal of the Society for Neuroscience 20080903
MUTYH Associated Polyposis (MAP). Current genomics 20080901
Lipoic acid rescues DBA mice from early-onset age-related hearing impairment. Neuroreport 20080827
Correlated cleavage of damaged DNA by bacterial and human 8-oxoguanine-DNA glycosylases. Biochemistry 20080826
Interplay of two major repair pathways in the processing of complex double-strand DNA breaks. DNA repair 20080802
Carcinogenic risk of copper gluconate evaluated by a rat medium-term liver carcinogenicity bioassay protocol. Archives of toxicology 20080801
Ionic strength and magnesium affect the specificity of Escherichia coli and human 8-oxoguanine-DNA glycosylases. The FEBS journal 20080801
SPR imaging for label-free multiplexed analyses of DNA N-glycosylase interactions with damaged DNA duplexes. The Analyst 20080801
Repair system of 7, 8-dihydro-8-oxoguanine as a defense line against carcinogenesis. Journal of radiation research 20080701
Inhibition of the 5' to 3' exonuclease activity of hEXO1 by 8-oxoguanine. Environmental and molecular mutagenesis 20080601
Oxidative stress impairs the repair of oxidative DNA base modifications in human skin fibroblasts and melanoma cells. DNA repair 20080601
DNA polymerases and oxidative damage: friends or foes? Current molecular pharmacology 20080601
Effect of oxidatively damaged DNA on the active site preorganization during nucleotide incorporation in a high fidelity polymerase from Bacillus stearothermophilus. Proteins 20080515
Lesion processing: high-fidelity versus lesion-bypass DNA polymerases. Trends in biochemical sciences 20080501
Antioxidant vitamins and cancer risk: is oxidative damage to DNA a relevant biomarker? European journal of nutrition 20080501
Catalytic involvement of CO2 in the mutagenesis caused by reactions of ONOO(-) with guanine. The journal of physical chemistry. B 20080417
An exploration of mechanisms for the transformation of 8-oxoguanine to guanidinohydantoin and spiroiminodihydantoin by density functional theory. Journal of the American Chemical Society 20080416
The relationship between 8-oxo-7,8-dihydro-2'-deoxyguanosine level and extent of cytosine methylation in leukocytes DNA of healthy subjects and in patients with colon adenomas and carcinomas. Mutation research 20080402
Aminoflavone induces oxidative DNA damage and reactive oxidative species-mediated apoptosis in breast cancer cells. International journal of cancer 20080401
Cells deficient in oxidative DNA damage repair genes Myh and Ogg1 are sensitive to oxidants with increased G2/M arrest and multinucleation. Carcinogenesis 20080401
Effect of amino acids on X-ray-induced hydrogen peroxide and hydroxyl radical formation in water and 8-oxoguanine in DNA. Biochemistry. Biokhimiia 20080401
Base excision repair dysfunction in a subgroup of patients with myelodysplastic syndrome. Leukemia 20080301
An abundant evolutionarily conserved CSB-PiggyBac fusion protein expressed in Cockayne syndrome. PLoS genetics 20080301
The genomics of colorectal cancer: state of the art. Current genomics 20080301
Separation of oxidatively damaged DNA nucleobases and nucleosides on packed and monolith C18 columns by HPLC-UV-EC. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080215
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Larger yield of cyclobutane dimers than 8-oxo-7,8-dihydroguanine in the DNA of UVA-irradiated human skin cells. Mutation research 20041122
Human ribosomal protein S3 interacts with DNA base excision repair proteins hAPE/Ref-1 and hOGG1. Biochemistry 20041109
Reaction intermediates in the catalytic mechanism of Escherichia coli MutY DNA glycosylase. The Journal of biological chemistry 20041105
Comparison of the effects of L-carnitine and acetyl-L-carnitine on carnitine levels, ambulatory activity, and oxidative stress biomarkers in the brain of old rats. Annals of the New York Academy of Sciences 20041101
Diet is not responsible for the presence of several oxidatively damaged DNA lesions in mouse urine. Free radical research 20041101
Structural basis for the recognition of the FapydG lesion (2,6-diamino-4-hydroxy-5-formamidopyrimidine) by formamidopyrimidine-DNA glycosylase. The Journal of biological chemistry 20041015
Suppression of chemically induced and spontaneously occurring oxidative mutagenesis by three alleles of human OGG1 gene encoding 8-hydroxyguanine DNA glycosylase. Mutation research 20041004
A novel splice-site variant of the base excision repair gene MYH is associated with production of an aberrant mRNA transcript encoding a truncated MYH protein not localized in the nucleus. Carcinogenesis 20041001
An oligonucleotide microarray for the monitoring of repair enzyme activity toward different DNA base damage. Analytical biochemistry 20041001
Spirodihydantoin is a minor product of 5-hydroxyisourate in urate oxidation. Organic letters 20040916
Stimulation of DNA glycosylase activity of OGG1 by NEIL1: functional collaboration between two human DNA glycosylases. Biochemistry 20040914
Differential ability of polymorphic OGG1 proteins to suppress mutagenesis induced by 8-hydroxyguanine in human cell in vivo. Carcinogenesis 20040901
Electrochemical study of quercetin-DNA interactions: part I. Analysis in incubated solutions. Bioelectrochemistry (Amsterdam, Netherlands) 20040901
Electrochemical study of quercetin-DNA interactions: part II. In situ sensing with DNA biosensors. Bioelectrochemistry (Amsterdam, Netherlands) 20040901
Analysis of 8-hydroxyguanine (8-OH-Gua) released from DNA by the formamidopyrimidine DNA glycosylase (Fpg) protein: a reliable method to estimate cellular oxidative stress. Journal of radiation research 20040901
Biology of Parkinson's disease: pathogenesis and pathophysiology of a multisystem neurodegenerative disorder. Dialogues in clinical neuroscience 20040901
Metallothionein-III prevents gamma-ray-induced 8-oxoguanine accumulation in normal and hOGG1-depleted cells. The Journal of biological chemistry 20040813
Cellular repair of oxidatively induced DNA base lesions is defective in prostate cancer cell lines, PC-3 and DU-145. Carcinogenesis 20040801
Oxidative DNA damage associated with combination of guanine and superoxide radicals and repair mechanisms via radical trapping. The Journal of biological chemistry 20040730
Accumulation of the oxidative base lesion 8-hydroxyguanine in DNA of tumor-prone mice defective in both the Myh and Ogg1 DNA glycosylases. Cancer research 20040701
Single extraction protocol for the analysis of 8-hydroxy-2'-deoxyguanosine (oxo8dG) and the associated activity of 8-oxoguanine DNA glycosylase. Journal of neuroscience methods 20040615
Aflatoxin B1 formamidopyrimidine adducts are preferentially repaired by the nucleotide excision repair pathway in vivo. Carcinogenesis 20040601
A high-throughput and sensitive methodology for the quantification of urinary 8-hydroxy-2'-deoxyguanosine: measurement with gas chromatography-mass spectrometry after single solid-phase extraction. The Biochemical journal 20040601
Electrochemical determination of 8-oxoguanine in the presence of uric acid. Bioelectrochemistry (Amsterdam, Netherlands) 20040601
Role of reactive oxygen species in skin carcinogenesis. Antioxidants & redox signaling 20040601
Oxidative damage to DNA of ovarian surface epithelial cells affected by ovulation: carcinogenic implication and chemoprevention. Experimental biology and medicine (Maywood, N.J.) 20040601
Development of an HPLC method with electrochemical detection of femtomoles of 8-oxo-7,8-dihydroguanine and 8-oxo-7,8-dihydro-2'-deoxyguanosine in the presence of uric acid. Talanta 20040528
Effect of 8-oxoguanine on transcription elongation by T7 RNA polymerase and mammalian RNA polymerase II. DNA repair 20040504
In vivo exposure to hyperoxia induces DNA damage in a population of alveolar type II epithelial cells. American journal of physiology. Lung cellular and molecular physiology 20040501
Role of inherited defects of MYH in the development of sporadic colorectal cancer. Genes, chromosomes & cancer 20040501
Oxygen tension regulates reactive oxygen generation and mutation of Helicobacter pylori. Free radical biology & medicine 20040501
Effects of melanin and manganese on DNA damage and repair in PC12-derived neurons. Free radical biology & medicine 20040501
Single-stranded breaks in DNA but not oxidative DNA base damages block transcriptional elongation by RNA polymerase II in HeLa cell nuclear extracts. The Journal of biological chemistry 20040430
Hydrogen peroxide induces topoisomerase I-mediated DNA damage and cell death. The Journal of biological chemistry 20040409
Mutagenicities of 8-hydroxyguanine and 2-hydroxyadenine produced by reactive oxygen species. Biological & pharmaceutical bulletin 20040401
Reactive oxygen species derived from the mitochondrial respiratory chain are not responsible for the basal levels of oxidative base modifications observed in nuclear DNA of Mammalian cells. Free radical biology & medicine 20040315
8-OxoG retards the activity of the ligase III/XRCC1 complex during the repair of a single-strand break, when present within a clustered DNA damage site. DNA repair 20040304
Overexpression and rapid purification of Escherichia coli formamidopyrimidine-DNA glycosylase. Protein expression and purification 20040301
Are we sure we know how to measure 8-oxo-7,8-dihydroguanine in DNA from human cells? Archives of biochemistry and biophysics 20040301
Molecular biology: ensuring error-free DNA repair. Nature 20040212
Structural basis for removal of adenine mispaired with 8-oxoguanine by MutY adenine DNA glycosylase. Nature 20040212
Characterization of human ribosomal protein S3 binding to 7,8-dihydro-8-oxoguanine and abasic sites by surface plasmon resonance. DNA repair 20040203
Hyperoxia-induced DNA damage causes decreased DNA methylation in human lung epithelial-like A549 cells. Antioxidants & redox signaling 20040201
Expression of base excision DNA repair genes is a sensitive biomarker for in vivo detection of chemical-induced chronic oxidative stress: identification of the molecular source of radicals responsible for DNA damage by peroxisome proliferators. Cancer research 20040201
Detection of a smaller, 32-kDa 8-oxoguanine DNA glycosylase 1 in 3'-methyl-4-dimethylamino-azobenzene-treated mouse liver. Cancer science 20040201
Cadmium-induced apoptosis in C6 glioma cells: influence of oxidative stress. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20040201
Different toxic, fibrogenic and mutagenic effects of four commercial quartz flours in the rat lung. International journal of hygiene and environmental health 20040201
DNA glycosylase recognition and catalysis. Current opinion in structural biology 20040201
Orchestration of base excision repair by controlling the rates of enzymatic activities. DNA repair 20040105
8-Oxoguanine induces intramolecular DNA damage but free 8-oxoguanine protects intermolecular DNA from oxidative stress. FEBS letters 20040102
Excision by the human methylpurine DNA N-glycosylase of cyanuric acid, a stable and mutagenic oxidation product of 8-oxo-7,8-dihydroguanine. International journal of radiation biology 20040101
Radiation-induced DNA damage: formation, measurement, and biochemical features. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20040101
Effects of 'second-hand' smoke on structure and function of fibroblasts, cells that are critical for tissue repair and remodeling. BMC cell biology 20040101
Potassium bromate but not X-rays cause unexpectedly elevated levels of DNA breakage similar to those induced by ultraviolet light in Cockayne syndrome (CS-B) fibroblasts. Cytogenetic and genome research 20040101
Protection of pulmonary epithelial cells from oxidative stress by hMYH adenine glycosylase. Respiratory research 20040101
[New non-hydrolyzable substrate analogs for 8-oxoguanine-DNA glycosylases]. Molekuliarnaia biologiia 20040101
Expression of the Drosophila melanogaster S3 ribosomal/repair protein in T24 human bladder cells. Anticancer research 20040101
UVA-induced degradation of 8-hydroxyguanine in oligonucleotide and the effect on its activities in yeast oligonucleotide transformation assay. Nucleic acids symposium series (2004) 20040101
DNA lesion recognition by the bacterial repair enzyme MutM. The Journal of biological chemistry 20031219
Detection of attomole quantities [correction of quantitites] of DNA targets on gold microelectrodes by electrocatalytic nucleobase oxidation. Analytical chemistry 20031201
DNA lesions derived from the site selective oxidation of Guanine by carbonate radical anions. Chemical research in toxicology 20031201
Strand-specific processing of 8-oxoguanine by the human mismatch repair pathway: inefficient removal of 8-oxoguanine paired with adenine or cytosine. DNA repair 20031121
Effect of the oxidized guanosine lesions spiroiminodihydantoin and guanidinohydantoin on proofreading by Escherichia coli DNA polymerase I (Klenow fragment) in different sequence contexts. Biochemistry 20031111
Role of XRCC1 in the coordination and stimulation of oxidative DNA damage repair initiated by the DNA glycosylase hOGG1. The Journal of biological chemistry 20031107
Oxidative DNA damage induced by benz[a]anthracene metabolites via redox cycles of quinone and unique non-quinone. Chemical research in toxicology 20031101
Oxidative DNA damage and glioma cell death induced by tetrahydropapaveroline. Mutation research 20031101
Transcription-coupled repair of 8-oxoguanine in human cells and its deficiency in some DNA repair diseases. Biochimie 20031101
Oxidative damage to DNA: formation, measurement and biochemical features. Mutation research 20031029
8-Oxoguanine DNA damage: at the crossroad of alternative repair pathways. Mutation research 20031029
Oxidative DNA damage in cancer patients: a cause or a consequence of the disease development? Mutation research 20031029
The two main DNA lesions 8-Oxo-7,8-dihydroguanine and 2,6-diamino-5-formamido-4-hydroxypyrimidine exhibit strongly different pairing properties. Angewandte Chemie (International ed. in English) 20031020
Oxidative DNA damage in peripheral leukocytes and its association with expression and polymorphisms of hOGG1: a study of adolescents in a high risk region for hepatocellular carcinoma in China. World journal of gastroenterology 20031015
Intramolecular electrocatalysis of 8-oxo-guanine oxidation: secondary structure control of electron transfer in osmium-labeled oligonucleotides. Inorganic chemistry 20031006
Better late than never for repair of miscoding lesions within a transcribed template. Molecular cell 20031001
Transcriptional mutagenesis induced by uracil and 8-oxoguanine in Escherichia coli. Molecular cell 20031001
Human MutY: gene structure, protein functions and interactions, and role in carcinogenesis. Cellular and molecular life sciences : CMLS 20031001
Age-dependent deficiency in import of mitochondrial DNA glycosylases required for repair of oxidatively damaged bases. Proceedings of the National Academy of Sciences of the United States of America 20030916
Evaluation of genotoxic risk and oxidative DNA damage in mammalian cells exposed to mycotoxins, patulin and citrinin. Toxicology and applied pharmacology 20030915
The molecular epidemiology of oxidative damage to DNA and cancer. Journal of the National Cancer Institute 20030903
DNA repair activity for oxidative damage and risk of lung cancer. Journal of the National Cancer Institute 20030903
Oxidized guanine lesions as modulators of gene transcription. Altered p50 binding affinity and repair shielding by 7,8-dihydro-8-oxo-2'-deoxyguanosine lesions in the NF-kappaB promoter element. Biochemistry 20030819
Products of oxidative DNA damage and repair as possible biomarkers of susceptibility to lung cancer. Cancer research 20030815
The hydantoin lesions formed from oxidation of 7,8-dihydro-8-oxoguanine are potent sources of replication errors in vivo. Biochemistry 20030812
Bipyrimidine photoproducts rather than oxidative lesions are the main type of DNA damage involved in the genotoxic effect of solar UVA radiation. Biochemistry 20030805
Urinary 8-hydroxydeoxyguanosine and its analogs as DNA marker of oxidative stress: development of an ELISA and measurement in both bladder and prostate cancers. Clinica chimica acta; international journal of clinical chemistry 20030801
Cell proliferation in liver of Mmh/Ogg1-deficient mice enhances mutation frequency because of the presence of 8-hydroxyguanine in DNA. Cancer research 20030715
Chemical restriction: strand cleavage by ammonia treatment at 8-oxoguanine yields biologically active DNA. Chembiochem : a European journal of chemical biology 20030707
High concentrations of excised oxidative DNA lesions in human cerebrospinal fluid. Clinical chemistry 20030701
Photochemical cross-linking of Escherichia coli Fpg protein to DNA duplexes containing phenyl(trifluoromethyl)diazirine groups. European journal of biochemistry 20030701
Electrostatic energy analysis of 8-oxoguanine DNA lesion-molecular dynamics study. Computational biology and chemistry 20030701
The mutation frequency of 8-oxo-7,8-dihydroguanine (8-oxodG) situated in a multiply damaged site: comparison of a single and two closely opposed 8-oxodG in Escherichia coli. DNA repair 20030611
Comparative analysis of 8-oxoG:C, 8-oxoG:A, A:C and C:C DNA repair in extracts from wild type or 8-oxoG DNA glycosylase deficient mammalian and bacterial cells. DNA repair 20030611
Oscillating formation of 8-oxoguanine during DNA oxidation. Journal of the American Chemical Society 20030604
Oxidative stress and predominant Abeta42(43) deposition in myopathies with rimmed vacuoles. Acta neuropathologica 20030601
Normal somatic hypermutation of Ig genes in the absence of 8-hydroxyguanine-DNA glycosylase. Journal of immunology (Baltimore, Md. : 1950) 20030601
Investigations on the inflammatory and genotoxic lung effects of two types of titanium dioxide: untreated and surface treated. Toxicology and applied pharmacology 20030601
Aldehydic DNA lesions induced by catechol estrogens in calf thymus DNA. Carcinogenesis 20030601
Suppressive activities of OGG1 and MYH proteins against G:C to T:A mutations caused by 8-hydroxyguanine but not by benzo[a]pyrene diol epoxide in human cells in vivo. Carcinogenesis 20030601
8-Oxoguanine enhances bending of DNA that favors binding to glycosylases. Journal of the American Chemical Society 20030521
Poly(ADP-ribose) polymerase-1 (PARP-1) is required in murine cell lines for base excision repair of oxidative DNA damage in the absence of DNA polymerase beta. The Journal of biological chemistry 20030516
Endonuclease IV enhances base excision repair of endonuclease III from Methanobacterium thermoautotrophicum. DNA repair 20030513
8-oxoguanine lesioned B-DNA molecule complexed with repair enzyme hOGG1: a molecular dynamics study. Journal of computational chemistry 20030501
A novel mechanism for preventing mutations caused by oxidation of guanine nucleotides. EMBO reports 20030501
Use of crosslinking for revealing the DNA phosphate groups forming specific contacts with the E. coli Fpg protein. Biochimie 20030501
hOGG1 Ser326Cys polymorphism and breast cancer risk among Asian women. Breast cancer research and treatment 20030501
Expression of hOGG1 protein during differentiation of HL-60 cells. Experimental & molecular medicine 20030430
Base excision repair synthesis of DNA containing 8-oxoguanine in Escherichia coli. Experimental & molecular medicine 20030430
Evidence for preferential mismatch repair of lagging strand DNA replication errors in yeast. Current biology : CB 20030429
Measurement of DNA oxidation in human cells by chromatographic and enzymic methods. Free radical biology & medicine 20030415
Characterization of an Escherichia coli mutant MutY with a cysteine to alanine mutation at the iron-sulfur cluster domain. Biochemistry 20030408
Primary fibroblasts of Cockayne syndrome patients are defective in cellular repair of 8-hydroxyguanine and 8-hydroxyadenine resulting from oxidative stress. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030401
Long-patch DNA repair synthesis during base excision repair in mammalian cells. EMBO reports 20030401
Arabidopsis thaliana Ogg1 protein excises 8-hydroxyguanine and 2,6-diamino-4-hydroxy-5-formamidopyrimidine from oxidatively damaged DNA containing multiple lesions. Biochemistry 20030318
Cadmium exposure down-regulates 8-oxoguanine DNA glycosylase expression in rat lung and alveolar epithelial cells. Toxicology 20030303
Product-assisted catalysis in base-excision DNA repair. Nature structural biology 20030301
Electron and hole transfer from DNA base radicals to oxidized products of guanine in DNA. Radiation research 20030301
Ogg1 knockout-associated lung tumorigenesis and its suppression by Mth1 gene disruption. Cancer research 20030301
Nutritional modulation of DNA repair in a human intervention study. Carcinogenesis 20030301
Oxidative DNA base modifications and polycyclic aromatic hydrocarbon DNA adducts in squamous cell carcinoma of larynx. Free radical research 20030301
Metaplastic potential of p53 down-regulation in ovarian surface epithelial cells affected by ovulation. Cancer letters 20030227
Marathon running alters the DNA base excision repair in human skeletal muscle. Life sciences 20030221
Accumulation of 8-oxoguanine in the cellular DNA and the alteration of the OGG1 expression during ischemia-reperfusion injury in the rat kidney. DNA repair 20030203
Hydroxyl radical is not the main reactive species involved in the degradation of DNA bases by copper in the presence of hydrogen peroxide. Chemical research in toxicology 20030201
8-hydroxydeoxyguanosine causes death of human leukemia cells deficient in 8-oxoguanine glycosylase 1 activity by inducing apoptosis. Molecular cancer research : MCR 20030201
Escherichia coli MutY and Fpg utilize a processive mechanism for target location. Biochemistry 20030128
An improved liquid chromatography/tandem mass spectrometry method for the determination of 8-oxo-7,8-dihydro-2'-deoxyguanosine in DNA samples using immunoaffinity column purification. Rapid communications in mass spectrometry : RCM 20030101
Hold tight (but not too tight) to get it right: accurate bypass of an 8-oxoguanine lesion by DNA polymerase beta. Structure (London, England : 1993) 20030101
Occupational exposure to heavy metals: DNA damage induction and DNA repair inhibition prove co-exposures to cadmium, cobalt and lead as more dangerous than hitherto expected. Carcinogenesis 20030101
Age-dependent increase of 8-oxoguanine-, hypoxanthine-, and uracil- DNA glycosylase activities in liver extracts from OXYS rats with inherited overgeneration of free radicals and Wistar rats. Medical science monitor : international medical journal of experimental and clinical research 20030101
Measurement of oxidative damage at individual gene levels by quantitative PCR using 8-hydroxyguanine glycosylase (OGG1). Mutation research 20030101
Ovarian responses to undernutrition in pregnant ewes, USA. Reproductive biology and endocrinology : RB&E 20030101
Preparation of DNA-protein complexes suitable for spectroscopic analysis. Methods in molecular medicine 20030101
Analysis of 8-hydroxydeoxyguanosine 5'-monophosphate (8-OH-dGMP) as a reliable marker of cellular oxidative DNA damage after gamma-irradiation. Environmental and molecular mutagenesis 20030101
Drosophila S3 ribosomal protein accelerates repair of 8-oxoguanine performed by human and mouse cell extracts. Environmental and molecular mutagenesis 20030101
Effect of S. cerevisiae APN1 protein on mammalian DNA base excision repair. Anticancer research 20030101
[Study of formation and elimination of 8-oxoguanine in DNA of the liver and brain of mice after gamma-irradiation]. Radiatsionnaia biologiia, radioecologiia 20030101
Efficiency, specificity and DNA polymerase-dependence of translesion replication across the oxidative DNA lesion 8-oxoguanine in human cells. Mutation research 20021229
In vitro nucleotide misinsertion opposite the oxidized guanosine lesions spiroiminodihydantoin and guanidinohydantoin and DNA synthesis past the lesions using Escherichia coli DNA polymerase I (Klenow fragment). Biochemistry 20021224
Oxidative nucleotide damage: consequences and prevention. Oncogene 20021216
8-Hydroxyguanosine repair is defective in some microsatellite stable colorectal cancer cells. Cancer research 20021215
Mitochondrial repair of 8-oxoguanine is deficient in Cockayne syndrome group B. Oncogene 20021212
Sorting the consequences of ionizing radiation: processing of 8-oxoguanine/abasic site lesions. DNA repair 20021205
High accumulation of oxidative DNA damage, 8-hydroxyguanine, in Mmh/Ogg1 deficient mice by chronic oxidative stress. Carcinogenesis 20021201
Comparative analysis of baseline 8-oxo-7,8-dihydroguanine in mammalian cell DNA, by different methods in different laboratories: an approach to consensus. Carcinogenesis 20021201
Ultraviolet-B-induced inactivation of human OGG1, the repair enzyme for removal of 8-oxoguanine in DNA. Photochemistry and photobiology 20021201
A global DNA repair mechanism involving the Cockayne syndrome B (CSB) gene product can prevent the in vivo accumulation of endogenous oxidative DNA base damage. Oncogene 20021128
The role of oxidative stress in the ochratoxin A-mediated toxicity in proximal tubular cells. Biochimica et biophysica acta 20021120
Functional crosstalk between hOgg1 and the helicase domain of Cockayne syndrome group B protein. DNA repair 20021103
Binding capacity of human YB-1 protein for RNA containing 8-oxoguanine. Biochemistry 20021022
Temperature-dependence of UV laser one-electron oxidative guanine modifications as a probe of local stacking fluctuations and conformational transitions. Journal of molecular biology 20021011
Acute arsenite-induced 8-hydroxyguanine is associated with inhibition of repair activity in cultured human cells. Biochemical and biophysical research communications 20021004
The level of 8-hydroxyguanine, a possible repair product of oxidative DNA damage, is higher in urine of cancer patients than in control subjects. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20021001
Structure and potential mutagenicity of new hydantoin products from guanosine and 8-oxo-7,8-dihydroguanine oxidation by transition metals. Environmental health perspectives 20021001
Guanine and 7,8-dihydro-8-oxo-guanine-specific oxidation in DNA by chromium(V). Environmental health perspectives 20021001
Oxidative stress in humans: validation of biomarkers of DNA damage. Carcinogenesis 20020901
Loss of oxidized and chlorinated bases in DNA treated with reactive oxygen species: implications for assessment of oxidative damage in vivo. Biochemical and biophysical research communications 20020830
The cockayne syndrome group B gene product is involved in cellular repair of 8-hydroxyadenine in DNA. The Journal of biological chemistry 20020823
Base excision repair of adenine/8-oxoguanine mispairs by an aphidicolin-sensitive DNA polymerase in human cell extracts. Oncogene 20020808
First principles calculations of the tautomers and pK(a) values of 8-oxoguanine: implications for mutagenicity and repair. Chemical research in toxicology 20020801
NTA and Fe(III)NTA: differential patterns of renal toxicity in subchronic studies. Human & experimental toxicology 20020801
Establishment and characterisation of six human biliary tract cancer cell lines. British journal of cancer 20020715
Yeast origins establish a strand bias for replicational mutagenesis. Molecular cell 20020701
Thermodynamic, kinetic, and structural basis for recognition and repair of 8-oxoguanine in DNA by Fpg protein from Escherichia coli. Biochemistry 20020618
Repair of clustered DNA lesions. Sequence-specific inhibition of long-patch base excision repair be 8-oxoguanine. The Journal of biological chemistry 20020614
Gene-specific oxidative DNA damage in Helicobacter pylori-infected human gastric mucosa. International journal of cancer 20020601
hOGG1 Ser(326)Cys polymorphism and modification by environmental factors of stomach cancer risk in Chinese. International journal of cancer 20020601
Mutagenic target for hydroxyl radicals generated in Escherichia coli mutant deficient in Mn- and Fe- superoxide dismutases and Fur, a repressor for iron-uptake systems. DNA repair 20020530
Global genome repair of 8-oxoG in hamster cells requires a functional CSB gene product. Oncogene 20020516
Translesion synthesis by human DNA polymerase eta across thymine glycol lesions. Biochemistry 20020514
Vitamin C prevents DNA mutation induced by oxidative stress. The Journal of biological chemistry 20020510
Repair of oxidative DNA damage in nuclear and mitochondrial DNA, and some changes with aging in mammalian cells. Free radical biology & medicine 20020501
Involvement of mammalian OGG1(MMH) in excision of the 8-hydroxyguanine residue in DNA. Free radical biology & medicine 20020501
A single nucleotide polymorphism at the splice donor site of the human MYH base excision repair genes results in reduced translation efficiency of its transcripts. Genes to cells : devoted to molecular & cellular mechanisms 20020501
A limited association of OGG1 Ser326Cys polymorphism for adenocarcinoma of the lung. Journal of epidemiology 20020501
Repair of 8-oxoG is slower in endogenous nuclear genes than in mitochondrial DNA and is without strand bias. DNA repair 20020429
Effects of a guanine-derived formamidopyrimidine lesion on DNA replication: translesion DNA synthesis, nucleotide insertion, and extension kinetics. The Journal of biological chemistry 20020426
The effect of DNA damage on the formation of protein/DNA complexes. Mutation research 20020425
Associations between hOGG1 sequence variants and prostate cancer susceptibility. Cancer research 20020415
Regulation of one-electron oxidation rate of guanine by base pairing with cytosine derivatives. Journal of the American Chemical Society 20020410
Functional interaction of MutY homolog with proliferating cell nuclear antigen in fission yeast, Schizosaccharomyces pombe. The Journal of biological chemistry 20020405
Impairment of mitochondrial DNA repair enzymes against accumulation of 8-oxo-guanine in the spinal motor neurons of amyotrophic lateral sclerosis. Acta neuropathologica 20020401
Molecular dynamics simulation of 7, 8-dihydro-8-oxoguanine DNA. Journal of biomolecular structure & dynamics 20020401
Association of the hOGG1 Ser326Cys polymorphism with lung cancer risk. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20020401
Reciprocal 'flipping' underlies substrate recognition and catalytic activation by the human 8-oxo-guanine DNA glycosylase. Journal of molecular biology 20020322
Activation of human MutS homologs by 8-oxo-guanine DNA damage. The Journal of biological chemistry 20020308
Relations between clusters of oxidatively damaged nucleotides and active or open nucleosomes in the rat Nth 1 gene. Oncogene 20020307
Defective repair of 8-hydroxyguanine in mitochondria of MCF-7 and MDA-MB-468 human breast cancer cell lines. Cancer research 20020301
DNA tandem lesions containing 8-oxo-7,8-dihydroguanine and formamido residues arise from intramolecular addition of thymine peroxyl radical to guanine. Chemical research in toxicology 20020301
Hypoxia induces mitochondrial DNA damage and stimulates expression of a DNA repair enzyme, the Escherichia coli MutY DNA glycosylase homolog (MYH), in vivo, in the rat brain. Journal of neurochemistry 20020301
Inter-laboratory validation of procedures for measuring 8-oxo-7,8-dihydroguanine/8-oxo-7,8-dihydro-2'-deoxyguanosine in DNA. Free radical research 20020301
Site-specific probing of oxidative reactivity and telomerase function using 7,8-dihydro-8-oxoguanine in telomeric DNA. Journal of the American Chemical Society 20020227
Replication-associated repair of adenine:8-oxoguanine mispairs by MYH. Current biology : CB 20020219
Stopped-flow kinetic studies of the interaction between Escherichia coli Fpg protein and DNA substrates. Biochemistry 20020205
Radiation sensitivity depends on OGG1 activity status in human leukemia cell lines. Free radical biology & medicine 20020201
Gender differences in steady-state levels of oxidative damage to DNA in healthy individuals. Free radical research 20020201
Oxidation of 7,8-dihydro-8-oxoguanine affords lesions that are potent sources of replication errors in vivo. Biochemistry 20020122
Repair of oxidized purines and damaged pyrimidines by E. coli Fpg protein: different roles of proline 2 and lysine 57 residues. Environmental and molecular mutagenesis 20020101
[18O]-labeled singlet oxygen as a tool for mechanistic studies of 8-oxo-7,8-dihydroguanine oxidative damage: detection of spiroiminodihydantoin, imidazolone and oxazolone derivatives. Biological chemistry 20020101
Transcription-coupled repair of 8-oxoguanine in human cells. Methods in enzymology 20020101
Effects of bile acids on base hydroxylation in a model of human colonic mucosal DNA. Cancer detection and prevention 20020101
Asymmetric directional mutation pressures in bacteria. Genome biology 20020101
Mitochondrial repair of 8-oxoguanine and changes with aging. Experimental gerontology 20020101
Backbone dynamics of DNA containing 8-oxoguanine: importance for substrate recognition by base excision repair glycosylases. Mutation research 20011219
Effect of overexpression of BCL-2 on cellular oxidative damage, nitric oxide production, antioxidant defenses, and the proteasome. Free radical biology & medicine 20011215
The Cockayne Syndrome group B gene product is involved in general genome base excision repair of 8-hydroxyguanine in DNA. The Journal of biological chemistry 20011207
DNA polymerase beta is the major dRP lyase involved in repair of oxidative base lesions in DNA by mammalian cell extracts. The EMBO journal 20011203
Effects of insulin and antioxidant on plasma 8-hydroxyguanine and tissue 8-hydroxydeoxyguanosine in streptozotocin-induced diabetic rats. Diabetes 20011201
An OGG1 orthologue encoding a functional 8-oxoguanine DNA glycosylase/lyase in Arabidopsis thaliana. Plant molecular biology 20011201
8-Oxo-7,8-dihydroguanine and 8-oxo-7,8-dihydro-2'-deoxyguanosine levels in human urine do not depend on diet. Free radical research 20011201
Increased base change mutations at G:C pairs in Escherichia coli deficient in endonuclease III and VIII. Journal of radiation research 20011201
UV laser photolysis of DNA: effect of duplex stability on charge-transfer efficiency. Journal of the American Chemical Society 20011121
Unique misinsertion specificity of poliota may decrease the mutagenic potential of deaminated cytosines. The EMBO journal 20011115
Ovulation-induced DNA damage in ovarian surface epithelial cells of ewes: prospective regulatory mechanisms of repair/survival and apoptosis. Biology of reproduction 20011101
A platinum(IV) complex oxidizes guanine to 8-oxo-guanine in DNA and RNA. Inorganic chemistry 20011022
Efficiency of excision of 8-oxo-guanine within DNA clustered damage by XRS5 nuclear extracts and purified human OGG1 protein. Biochemistry 20011002
Fission yeast (Schizosaccharomyces pombe) cells defective in the MutY-homologous glycosylase activity have a mutator phenotype and are sensitive to hydrogen peroxide. Molecular genetics and genomics : MGG 20011001
Direct photocleavage of HIV-DNA by quinacridine derivatives triggered by triplex formation. Journal of the American Chemical Society 20010926
Effect of single mutations on the specificity of Escherichia coli FPG protein for excision of purine lesions from DNA damaged by free radicals. Free radical biology & medicine 20010915
Human Ogg1, a protein involved in the repair of 8-oxoguanine, is inhibited by nitric oxide. Cancer research 20010901
Imaging techniques used for the detection of 8-oxoguanine adducts and DNA repair proteins in cells and tissues. Experimental gerontology 20010901
OGG1 protein suppresses G:C-->T:A mutation in a shuttle vector containing 8-hydroxyguanine in human cells. Carcinogenesis 20010901
Age-related and tissue-specific accumulation of oxidative DNA base damage in 7,8-dihydro-8-oxoguanine-DNA glycosylase (Ogg1) deficient mice. Carcinogenesis 20010901
Direct oxidation of guanine and 7,8-dihydro-8-oxoguanine in DNA by a high-valent chromium complex: a possible mechanism for chromate genotoxicity. Chemical research in toxicology 20010901
Sequence specificity of the 8-hydroxyguanine repair activity in rat organs. Journal of radiation research 20010901
Specific binding of 8-oxoguanine-containing RNA to polynucleotide phosphorylase protein. Biochemistry 20010821
Age-related radical-induced DNA damage is linked to prostate cancer. Cancer research 20010815
DNA repair activity of 8-oxoguanine DNA glycosylase 1 (OGG1) in human lymphocytes is not dependent on genetic polymorphism Ser326/Cys326. Mutation research 20010809
Ntg2 of Saccharomyces cerevisiae repairs the oxidation products of 8-hydroxyguanine. Biochemical and biophysical research communications 20010803
The OGG1 gene encodes a repair enzyme for oxidatively damaged DNA and is involved in human carcinogenesis. Antioxidants & redox signaling 20010801
[Repair mechanism of oxidative DNA damages]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20010801
Polyploidy associated with oxidative injury attenuates proliferative potential of cells. Journal of cell science 20010801
Conversion of the bifunctional 8-oxoguanine/beta-delta apurinic/apyrimidinic DNA repair activities of Drosophila ribosomal protein S3 into the human S3 monofunctional beta-elimination catalyst through a single amino acid change. The Journal of biological chemistry 20010720
Repair of 8-oxodeoxyguanosine lesions in mitochondrial dna depends on the oxoguanine dna glycosylase (OGG1) gene and 8-oxoguanine accumulates in the mitochondrial dna of OGG1-defective mice. Cancer research 20010715
Cellular effects of 5-formyluracil in DNA. Mutation research 20010712
DNA repair excision nuclease attacks undamaged DNA. A potential source of spontaneous mutations. The Journal of biological chemistry 20010706
Inter-individual differences in repair of DNA base oxidation, measured in vitro with the comet assay. Mutagenesis 20010701
Effect of proteasome inhibition on cellular oxidative damage, antioxidant defences and nitric oxide production. Journal of neurochemistry 20010701
hMYH cell cycle-dependent expression, subcellular localization and association with replication foci: evidence suggesting replication-coupled repair of adenine:8-oxoguanine mispairs. Nucleic acids research 20010701
Effect of overexpression of wild-type and mutant Cu/Zn-superoxide dismutases on oxidative stress and cell death induced by hydrogen peroxide, 4-hydroxynonenal or serum deprivation: potentiation of injury by ALS-related mutant superoxide dismutases and protection by Bcl-2. Journal of neurochemistry 20010701
The pyrimidine ring-opened derivative of 1,N6-ethenoadenine is excised from DNA by the Escherichia coli Fpg and Nth proteins. The Journal of biological chemistry 20010615
Determination of 8-oxoguanine in individual cell nucleus of gamma-irradiated mammalian cells. Radiation research 20010601
An in vivo approach to identifying sequence context of 8-oxoguanine mutagenesis. Biochemical and biophysical research communications 20010601
[Biological significance of base damage and its repair in brain and neurons]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20010601
[Repair networks for base damage and single-strand breaks]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20010601
Oxidative cellular damage and the reduction of APE/Ref-1 expression after experimental traumatic brain injury. Neurobiology of disease 20010601
Ser326Cys polymorphism in hOGG1 gene and risk of esophageal cancer in a Chinese population. International journal of cancer 20010520
Recognition and kinetics for excision of a base lesion within clustered DNA damage by the Escherichia coli proteins Fpg and Nth. Biochemistry 20010515
Spontaneous loss-of-function mutations of the 8-oxoguanine DNA glycosylase gene in mice and exploration of the possible implication of the gene in senescence. Free radical biology & medicine 20010515
Somatic mutations and single nucleotide polymorphisms of base excision repair genes involved in the repair of 8-hydroxyguanine in damaged DNA. Cancer letters 20010510
Biomonitoring on carcinogenic metals and oxidative DNA damage in a cross-sectional study. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20010501
Oxidative DNA damage, antioxidants and DNA repair: applications of the comet assay. Biochemical Society transactions 20010501
Base excision and DNA binding activities of human alkyladenine DNA glycosylase are sensitive to the base paired with a lesion. The Journal of biological chemistry 20010420
Oxidative DNA damage and repair in experimental atherosclerosis are reversed by dietary lipid lowering. Circulation research 20010413
Quartz exposure of the rat lung leads to a linear dose response in inflammation but not in oxidative DNA damage and mutagenicity. American journal of respiratory cell and molecular biology 20010401
Serum 8-hydroxy-guanine levels are increased in diabetic patients. Diabetes care 20010401
Possible cause of G-C-->C-G transversion mutation by guanine oxidation product, imidazolone. Chemistry & biology 20010401
GTP cyclohydrolase I feedback regulatory protein-dependent and -independent inhibitors of GTP cyclohydrolase I. Archives of biochemistry and biophysics 20010401
A functional OGG1 homologue from Arabidopsis thaliana. Molecular genetics and genomics : MGG 20010401
Debenzylation of O(6)-benzyl-8-oxoguanine in human liver: implications for O(6)-benzylguanine metabolism. Biochemical pharmacology 20010315
The Drosophila S3 multifunctional DNA repair/ribosomal protein protects Fanconi anemia cells against oxidative DNA damaging agents. Mutation research 20010307
Rates of base excision repair are not solely dependent on levels of initiating enzymes. Carcinogenesis 20010301
New biochemical markers in Alzheimer disease. Archives of neurology 20010301
Ratio of 8-hydroxyguanine in intact DNA to free 8-hydroxyguanine is increased in Alzheimer disease ventricular cerebrospinal fluid. Archives of neurology 20010301
Fidelity of nucleotide insertion at 8-oxo-7,8-dihydroguanine by mammalian DNA polymerase delta. Steady-state and pre-steady-state kinetic analysis. The Journal of biological chemistry 20010209
Significant differences in the cellular and molecular reactions of rat and hamster lung after quartz exposure. Toxicology letters 20010203
Changes in DNA 8-hydroxyguanine levels, 8-hydroxyguanine repair activity, and hOGG1 and hMTH1 mRNA expression in human lung alveolar epithelial cells induced by crocidolite asbestos. Carcinogenesis 20010201
Effect of overexpression of wild-type and mutant Cu/Zn-superoxide dismutases on oxidative damage and antioxidant defences: relevance to Down's syndrome and familial amyotrophic lateral sclerosis. Journal of neurochemistry 20010201
Effect of the overexpression of wild-type or mutant alpha-synuclein on cell susceptibility to insult. Journal of neurochemistry 20010201
Genetic changes of hOGG1 and the activity of oh8Gua glycosylase in colon cancer. European journal of cancer (Oxford, England : 1990) 20010201
Miscoding and misincorporation of 8-oxo-guanine during leading and lagging strand synthesis in Escherichia coli. Molecular & general genetics : MGG 20010201
Effect of endogenous carotenoids on 'adaptive' mutation in Escherichia coli FC40. Mutation research 20010125
tert-Butoxyl radicals generate mainly 7,8-dihydro-8-oxoguanine in DNA. Mutation research 20010105
Repair and mutagenic potential of oxaluric acid, a major product of singlet oxygen-mediated oxidation of 8-oxo-7,8-dihydroguanine. Chemical research in toxicology 20010101
Evidence of a no-effect level in silica-induced rat lung mutagenicity but not in fibrogenicity. Archives of toxicology 20010101
Mammalian Ogg1/Mmh gene plays a major role in repair of the 8-hydroxyguanine lesion in DNA. Progress in nucleic acid research and molecular biology 20010101
Multiple DNA glycosylases for repair of 8-oxoguanine and their potential in vivo functions. Progress in nucleic acid research and molecular biology 20010101
DNA substrates containing defined oxidative base lesions and their application to study substrate specificities of base excision repair enzymes. Progress in nucleic acid research and molecular biology 20010101
Base excision repair in nuclear and mitochondrial DNA. Progress in nucleic acid research and molecular biology 20010101
The mechanism of switching among multiple BER pathways. Progress in nucleic acid research and molecular biology 20010101
Potential double-flipping mechanism by E. coli MutY. Progress in nucleic acid research and molecular biology 20010101
Regulation of intracellular localization of human MTH1, OGG1, and MYH proteins for repair of oxidative DNA damage. Progress in nucleic acid research and molecular biology 20010101
Repair of 8-oxoguanine and Ogg1-incised apurinic sites in a CHO cell line. Progress in nucleic acid research and molecular biology 20010101
Consequences of haemolysis without haptoglobin. Redox report : communications in free radical research 20010101
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