Home Other Building Blocks 1-(2-Hydroxy-4-morpholinophenyl)ethanone

1-(2-Hydroxy-4-morpholinophenyl)ethanone

CAS No.:
404009-40-1
Catalog Number:
AG00CKSK
Molecular Formula:
Molecular Weight:
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
25mg
≥ 98% (HPLC)
1 week
United States
$155
- +
100mg
≥ 98% (HPLC)
1 week
United States
$243
- +
250mg
≥ 98% (HPLC)
1 week
United States
$447
- +
1g
≥ 98% (HPLC)
1 week
United States
$1266
- +
Product Description
Catalog Number:
AG00CKSK
Chemical Name:
1-(2-Hydroxy-4-morpholinophenyl)ethanone
CAS Number:
404009-40-1
MDL Number:
MFCD07370140
IUPAC Name:
1-(2-hydroxy-4-morpholin-4-ylphenyl)ethanone
InChI:
InChI=1S/C12H15NO3/c1-9(14)11-3-2-10(8-12(11)15)13-4-6-16-7-5-13/h2-3,8,15H,4-7H2,1H3
InChI Key:
YHKSBKQXCWHTQL-UHFFFAOYSA-N
Properties
Complexity:
251  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
221.105g/mol
Formal Charge:
0
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
221.256g/mol
Monoisotopic Mass:
221.105g/mol
Rotatable Bond Count:
2  
Topological Polar Surface Area:
49.8A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.8  
Literature
Title Journal
A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery. The Biochemical journal 20130415
Modulation of DNA repair by pharmacological inhibitors of the PIKK protein kinase family. Bioorganic & medicinal chemistry letters 20120901
Improved synthesis of a DNA-dependent protein kinase inhibitor IC86621. Archives of pharmacal research 20120301
Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity. Nature biotechnology 20111101
DNA-PKcs deficiency leads to persistence of oxidatively induced clustered DNA lesions in human tumor cells. Free radical biology & medicine 20100515
Lithium-mediated protection of hippocampal cells involves enhancement of DNA-PK-dependent repair in mice. The Journal of clinical investigation 20090501
The kinase activity of DNA-PK is required to protect mammalian telomeres. DNA repair 20040304
DNA-dependent protein kinase inhibitors as drug candidates for the treatment of cancer. Molecular cancer therapeutics 20031201
Interactive competition between homologous recombination and non-homologous end joining. Molecular cancer research : MCR 20031001
Properties